Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_049769939.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049774963.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049782748.1	14	Reactome: R-HSA-2565942;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-428890;Reactome: R-HSA-380259;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Role of ABL in ROBO-SLIT signaling";"Loss of Nlp from mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049785613.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_049788040.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049787596.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049768899.1	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453	"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Meiotic recombination";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response"
XP_049774397.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049781418.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049763059.1	4	MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism"
XP_049775623.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049762287.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049773694.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049764976.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049780812.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_049772863.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049778533.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049782901.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781792.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049773385.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_049773640.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_049779806.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895	"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis"
XP_049783916.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_049765477.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_049786190.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049768241.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_049784855.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049775180.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_049770948.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781821.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51	"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_049771396.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049777666.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049787245.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049765981.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049783029.1	6	MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317	"Stachyose degradation";"Galactose metabolism";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_049787252.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049777026.1	18	Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-8953750;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;MetaCyc: PWY-7511;Reactome: R-HSA-6796648;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Protein ubiquitination";"TP53 Regulates Transcription of DNA Repair Genes";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_049775179.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_049784471.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049767763.1	21	Reactome: R-HSA-168927;Reactome: R-HSA-5603027;Reactome: R-HSA-937039;Reactome: R-HSA-1810476;Reactome: R-HSA-5684264;Reactome: R-HSA-933542;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5602636;Reactome: R-HSA-9020702;Reactome: R-HSA-5357905;Reactome: R-HSA-1236974;Reactome: R-HSA-937041;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-933543;Reactome: R-HSA-5603029;Reactome: R-HSA-202424	"TICAM1, RIP1-mediated IKK complex recruitment";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"IRAK1 recruits IKK complex";"RIP-mediated NFkB activation via ZBP1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TRAF6 mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"IKBKB deficiency causes SCID";"Interleukin-1 signaling";"Regulation of TNFR1 signaling";"ER-Phagosome pathway";"IKK complex recruitment mediated by RIP1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"IkBA variant leads to EDA-ID";"Downstream TCR signaling"
XP_049767838.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049788004.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049768773.1	28	Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-3371511;Reactome: R-HSA-110314;Reactome: R-HSA-5696397	"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Meiotic recombination";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"HSF1 activation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049779327.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049786573.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049762325.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049775317.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049784519.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049781359.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_049783437.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049765583.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049784809.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049781824.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51	"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism"
XP_049787482.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049768586.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049765470.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333	"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049782355.1	7	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_049788105.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049785675.1	9	Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-1362277;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-176187	"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress"
XP_049776829.1	12	KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-5744;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7118;MetaCyc: PWY-6969;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-6728;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294	"Glyoxylate and dicarboxylate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Methylaspartate cycle";"Pyruvate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV"
XP_049763130.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049783341.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_049770403.1	7	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-166208	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling"
XP_049783611.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins"
XP_049782781.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049766352.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049780930.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049781062.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049780822.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049770979.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049785660.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Kinesins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy"
XP_049765227.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_049766466.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049782403.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049785002.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049776081.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049780358.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049782791.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049762698.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049767670.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-110362	"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair"
XP_049787043.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049784820.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049770317.1	11	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779	"Ub-specific processing proteases";"HATs acetylate histones";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049768920.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756	"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Synthesis of PC";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation"
XP_049787385.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049787673.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049777325.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049762610.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049780670.1	14	MetaCyc: PWY-8055;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_049781354.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049762983.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049776035.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049767233.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049772528.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049774952.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049773951.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049780355.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049768149.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049786297.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049776046.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383	"EGFR downregulation";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion"
XP_049765798.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049764653.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_049787041.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049762683.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049764325.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-400253	"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock"
XP_049764291.1	26	Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-1445148	"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049772239.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049787767.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049778414.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751	"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Regulation of PTEN stability and activity"
XP_049785039.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049765476.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049782861.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049776273.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049763957.1	24	Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878	"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport"
XP_049779558.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049767036.1	7	KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism"
XP_049771775.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049787882.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049767788.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049766445.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-8853884	"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX"
XP_049784212.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049784071.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049781340.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049774844.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049778612.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_049770836.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049766334.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049783989.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049787164.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049765292.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049787649.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049765228.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049782414.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049773939.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_049764717.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049781071.1	26	Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840	"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_049766062.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_049777394.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049773855.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049781344.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049766622.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway"
XP_049769159.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049763675.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_049775664.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049774805.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049785891.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049776169.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749	"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated"
XP_049788154.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049773362.1	8	Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001	"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade"
XP_049784679.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049782669.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049775371.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049786655.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049765840.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049763256.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049775840.1	22	MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-7724;MetaCyc: PWY-7728;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_049778074.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049763811.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049775919.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049777370.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049767053.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049783377.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049762569.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049778725.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049778545.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049788192.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_049775455.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049773770.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049785582.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_049787289.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049779791.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049785450.1	12	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"NRAGE signals death through JNK";"Relaxin signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049764808.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049785542.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049767674.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-110357	"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1"
XP_049765839.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression";"ESR-mediated signaling"
XP_049764116.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712	"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling"
XP_049766509.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049762202.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_049777807.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049767355.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_049762224.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049775104.1	1	Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049769229.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049770550.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_049772914.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049787989.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049782093.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049782873.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049772223.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049785795.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049775828.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049788203.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049781952.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_049787225.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_049787329.1	34	Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-170822	"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_049766026.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_049784330.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway"
XP_049771665.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049765259.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049786587.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049773751.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049768302.1	17	KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7115	"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049779615.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049781573.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_049785327.1	8	KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism"
XP_049784552.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049777561.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049778110.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049766283.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049782993.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049770442.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049774774.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049784937.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-735	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis"
XP_049787185.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774995.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049771198.1	17	Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-202424	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ca2+ pathway";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling"
XP_049775836.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049783957.1	7	Reactome: R-HSA-4086400;Reactome: R-HSA-4641258;Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598	"PCP/CE pathway";"Degradation of DVL";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins"
XP_049767799.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51	"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism"
XP_049774990.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049772999.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049769731.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049783870.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049773953.1	9	MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901	"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_049769094.1	9	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection"
XP_049784170.1	5	MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_049778096.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049768870.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049771600.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049784771.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7279	"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_049764949.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049766124.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049778897.1	3	KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741	"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049786528.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049786470.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_049774472.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049772390.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049774533.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049781477.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression"
XP_049775394.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049786306.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049777553.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049784337.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049778071.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049788417.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049767469.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_049777321.1	6	KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)"
XP_049765770.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049784752.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049764850.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049783244.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint"
XP_049769907.1	10	KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1	"Fructose and mannose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism"
XP_049777404.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049786071.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049788423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049768589.1	10	KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855204;MetaCyc: PWY-6554;MetaCyc: PWY-6365;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;Reactome: R-HSA-983231;MetaCyc: PWY-6366	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"
XP_049783877.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049786237.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049787529.1	11	KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9	"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis"
XP_049785756.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828	"VLDLR internalisation and degradation";"LDL clearance";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis"
XP_049776370.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049780915.1	10	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"RSK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049779724.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049768811.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049778100.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049782157.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049787112.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049765223.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049763706.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_049774062.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049776571.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049775997.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049776949.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049787560.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049787429.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049781391.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049785202.1	7	Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352	"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis"
XP_049778083.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049762216.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049767649.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049767037.1	7	KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22	"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_049775254.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049783122.1	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_049767261.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049783181.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049787693.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis"
XP_049777177.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049774007.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049782121.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049768163.1	12	KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25	"Monobactam biosynthesis";"Selenate reduction";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Purine metabolism";"Selenocompound metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism"
XP_049783219.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049767794.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049783362.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049765946.1	4	MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072	"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization"
XP_049770743.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049765298.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I"
XP_049767183.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049784961.1	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_049775626.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049774887.1	6	KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403	"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)"
XP_049779787.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049778109.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15	"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism"
XP_049788357.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_049779034.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_049783303.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049774535.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049785192.1	9	Reactome: R-HSA-446193;Reactome: R-HSA-5633231;KEGG: 00513+2.4.1.141;MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6385;MetaCyc: PWY-6470	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
XP_049775395.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049773413.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_049780983.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049778500.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049784605.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049787386.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049768050.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049779925.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049777800.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049778502.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049774417.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049766344.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049781667.1	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004	"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I"
XP_049785031.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049768480.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049784211.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_049774430.1	10	MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-1722;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-5030	"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III"
XP_049763078.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049763224.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049785337.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049781265.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_049780932.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381070	"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones"
XP_049779476.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049762634.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_049779053.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049765399.1	14	MetaCyc: PWY-5076;MetaCyc: PWY-7767;MetaCyc: PWY-5101;Reactome: R-HSA-70895;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5108;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5104;KEGG: 00270+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42	"L-leucine degradation III";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis V";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II";"L-isoleucine biosynthesis IV";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis"
XP_049774393.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049784724.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049785516.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049767665.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049767019.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049776828.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049765814.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049783707.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-6724;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;Reactome: R-HSA-6798695	"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch degradation II";"Glycogen degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Neutrophil degranulation"
XP_049773702.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_049785032.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049786661.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049778985.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049762653.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049787001.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_049769630.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780878.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049782751.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049778297.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049778490.1	5	Reactome: R-HSA-1234176;Reactome: R-HSA-1234174;Reactome: R-HSA-8849473;Reactome: R-HSA-1234158;Reactome: R-HSA-8951664	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cellular response to hypoxia";"PTK6 Expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Neddylation"
XP_049781353.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049786337.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049779491.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049787310.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049787224.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_049770661.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049784381.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049783579.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049774359.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy"
XP_049785462.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049779596.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049772934.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049777477.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049774210.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_049766670.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049765557.1	3	Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Ub-specific processing proteases";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778537.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049766967.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049785493.1	11	MetaCyc: PWY-6549;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675	"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)"
XP_049770245.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049786882.1	6	KEGG: 00670+2.1.2.5;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030;Reactome: R-HSA-70921;MetaCyc: PWY-5497;KEGG: 00340+2.1.2.5	"One carbon pool by folate";"One carbon pool by folate";"L-histidine degradation III";"Histidine catabolism";"Purine nucleobases degradation II (anaerobic)";"Histidine metabolism"
XP_049767656.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787674.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049775832.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049786804.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049765922.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049780719.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049773537.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049783595.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049776270.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049784638.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049787350.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049787006.1	13	Reactome: R-HSA-5362768;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-9646399;Reactome: R-HSA-8866654;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-110320	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"HSF1 activation";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"Protein methylation";"Aggrephagy";"E3 ubiquitin ligases ubiquitinate target proteins";"Neutrophil degranulation";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Translesion Synthesis by POLH"
XP_049773615.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_049781326.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_049764667.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389977	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway"
XP_049785993.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049776979.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049788141.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049774390.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049762732.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049777048.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049787842.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049773741.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049766853.1	19	KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;Reactome: R-HSA-71403	"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Methane metabolism";"Citric acid cycle (TCA cycle)"
XP_049786260.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049774778.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049772032.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783984.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049785251.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5689880	"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Ub-specific processing proteases"
XP_049776974.1	11	Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170	"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions"
XP_049777522.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049774106.1	5	MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2	"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism"
XP_049769708.1	3	KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_049786027.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049774031.1	18	KEGG: 00970+6.1.1.1;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-379726;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Aminoacyl-tRNA biosynthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial tRNA aminoacylation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049780431.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049780076.1	10	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-3108214;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"SUMOylation of DNA damage response and repair proteins";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_049771629.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049788118.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049776877.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049781390.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049768500.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367	"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism"
XP_049784421.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049766735.1	7	KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22	"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_049768195.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049765129.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049784038.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049786593.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER"
XP_049773695.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_049762358.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049786755.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_049775315.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049783893.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_049775827.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049768496.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049781467.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049771097.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049766741.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Degradation of the extracellular matrix";"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049784777.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049785249.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049763297.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049785499.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049787244.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049773783.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_049769977.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049769208.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049774769.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049766823.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049784594.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_049777060.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049773152.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049762984.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049785823.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_049777806.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763233.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049775266.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049779054.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049783193.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777886.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884	"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX"
XP_049777338.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049772253.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049779912.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775224.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049782641.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_049770525.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049787904.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049775101.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049778787.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049765065.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049764650.1	33	MetaCyc: PWY-5079;MetaCyc: PWY-6587;KEGG: 00071+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-7013;MetaCyc: PWY-7396;Reactome: R-HSA-71384;MetaCyc: PWY-3162;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-7118;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6313;MetaCyc: PWY-5082;MetaCyc: PWY-6802;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5076;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-5078;MetaCyc: PWY-6333;KEGG: 00680+1.1.1.284;KEGG: 00350+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6871;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5751	"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol III";"Fatty acid degradation";"Formaldehyde oxidation II (glutathione-dependent)";"(S)-propane-1,2-diol degradation";"Butanol and isobutanol biosynthesis (engineered)";"Ethanol oxidation";"L-tryptophan degradation V (side chain pathway)";"alpha-Linolenic acid metabolism";"L-valine degradation II";"Chitin degradation to ethanol";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Serotonin degradation";"L-methionine degradation III";"Salidroside biosynthesis";"Glycolysis / Gluconeogenesis";"Noradrenaline and adrenaline degradation";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol I";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol II";"L-leucine degradation III";"Naphthalene degradation";"Protein S-nitrosylation and denitrosylation";"L-isoleucine degradation II";"Acetaldehyde biosynthesis I";"Methane metabolism";"Tyrosine metabolism";"Chloroalkane and chloroalkene degradation";"3-methylbutanol biosynthesis (engineered)";"Retinol metabolism";"Phenylethanol biosynthesis"
XP_049787668.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049778405.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110328	"Meiotic synapsis";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049785775.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049774527.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049765942.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049786722.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049784425.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049786450.1	6	KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66	"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_049763252.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049767035.1	7	KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22	"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_049785135.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859	"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly"
XP_049770367.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049777334.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049786743.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049783679.1	11	Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972	"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049763834.1	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
XP_049774026.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049772058.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049776904.1	33	Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159236	"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049767836.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049773785.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049772735.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049767244.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049771323.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway"
XP_049784123.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049764107.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049777528.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049774407.1	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049768160.1	12	KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-5278;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340	"Selenocompound metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Sulfite oxidation III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Selenate reduction";"Monobactam biosynthesis";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfate activation for sulfonation"
XP_049773837.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049783900.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049767470.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_049784411.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_049766515.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049782915.1	7	MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204	"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol"
XP_049782173.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049763239.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_049785705.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049771590.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049779915.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049779226.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049768178.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes"
XP_049786963.1	8	MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533	"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis"
XP_049774787.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049764635.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049769272.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049766505.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049781345.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049773046.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049771666.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049786509.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049767579.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049778291.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049768161.1	12	KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683	"Sulfur metabolism";"Monobactam biosynthesis";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III"
XP_049783371.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049769729.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049764179.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049775794.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049767608.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_049781582.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049786576.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049765766.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049778246.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049765585.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049776077.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_049778120.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049776072.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049785704.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049769067.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049766792.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049762777.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_049777330.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049781963.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049763614.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049768421.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049777329.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049783902.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049780356.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049763399.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049776253.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049775415.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049763821.1	17	Reactome: R-HSA-6796648;Reactome: R-HSA-75035;Reactome: R-HSA-1433557;Reactome: R-HSA-69601;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8953750	"TP53 Regulates Transcription of DNA Repair Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Signaling by SCF-KIT";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Transcriptional Regulation by E2F6"
XP_049767156.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049784072.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049781393.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049786270.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
XP_049765225.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049780588.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049762150.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775334.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049783658.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049774714.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049780199.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human immunodeficiency virus 1 infection"
XP_049785502.1	11	MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-210455	"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism"
XP_049774906.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049767184.1	4	Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049779229.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049767275.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049774810.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049769256.1	16	Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-9018519;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"Estrogen-dependent gene expression";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049784567.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049767663.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049762311.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049766669.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5628897	"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes"
XP_049775418.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049783080.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049776361.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049784035.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049783085.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049775103.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049785626.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049778907.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049766439.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049782974.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_049775380.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049782139.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape"
XP_049778380.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049787039.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049766996.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049767017.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049784595.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049776781.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049767238.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049782525.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049786821.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049767807.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825	"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis"
XP_049775465.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049785329.1	8	KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_049785596.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049770714.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049768167.1	12	KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-5278;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340	"Purine metabolism";"Selenocompound metabolism";"Transport and synthesis of PAPS";"Sulfite oxidation III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Monobactam biosynthesis";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation"
XP_049781843.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534	"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4"
XP_049763608.1	35	Reactome: R-HSA-512988;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-5578775;Reactome: R-HSA-380284;Reactome: R-HSA-422356;Reactome: R-HSA-442720;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610787;Reactome: R-HSA-9634600;Reactome: R-HSA-5610780;Reactome: R-HSA-180024;Reactome: R-HSA-8853659;Reactome: R-HSA-2565942;Reactome: R-HSA-163358;Reactome: R-HSA-8963896;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-381676;Reactome: R-HSA-4420097;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-9022692;Reactome: R-HSA-9022535;Reactome: R-HSA-380259;Reactome: R-HSA-163560;Reactome: R-HSA-380320;Reactome: R-HSA-9010642;Reactome: R-HSA-8854518;Reactome: R-HSA-5610783	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Ion homeostasis";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"mTOR signaling pathway";"Hedgehog 'off' state";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Degradation of GLI1 by the proteasome";"DARPP-32 events";"RET signaling";"Regulation of PLK1 Activity at G2/M Transition";"PKA-mediated phosphorylation of key metabolic factors";"HDL assembly";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFA-VEGFR2 Pathway";"Rap1 signalling";"PKA activation";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of MECP2 expression and activity";"Loss of phosphorylation of MECP2 at T308";"Loss of Nlp from mitotic centrosomes";"Triglyceride catabolism";"Recruitment of NuMA to mitotic centrosomes";"ROBO receptors bind AKAP5";"AURKA Activation by TPX2";"Degradation of GLI2 by the proteasome"
XP_049778959.1	12	Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"Biotin transport and metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049771366.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049764923.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049787633.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049772947.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049785323.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism"
XP_049786044.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049768041.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049774561.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049762429.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049771193.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049780688.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049780933.1	7	Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381183	"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_049775860.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_049763108.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049787478.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049787181.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_049786603.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049775441.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_049776551.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049765811.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049785688.1	8	MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049766951.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049781763.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049784527.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7337	"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_049773412.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049786829.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049786579.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049780513.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049773208.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049763388.1	10	Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Neddylation"
XP_049780124.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_049767619.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049786665.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_049778369.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_049778252.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049763336.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049788279.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049781342.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049765554.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049773129.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049776121.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049762940.1	9	MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049767295.1	17	KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;KEGG: 00061+6.4.1.2	"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis"
XP_049778039.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049771924.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049762587.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049773874.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049786251.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049787933.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_049766965.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049778203.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049788123.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049778800.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049772196.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049767203.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049777599.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049784470.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049776117.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049774974.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049784713.1	10	Reactome: R-HSA-977225;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;MetaCyc: PWY-7394;Reactome: R-HSA-3000171	"Amyloid fiber formation";"Retinoid metabolism and transport";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions"
XP_049783480.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049763241.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_049762982.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049778736.1	11	Reactome: R-HSA-68827;Reactome: R-HSA-1362277;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_049779816.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049780887.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049781347.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049764782.1	22	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7592;MetaCyc: PWY-7726;MetaCyc: PWY-7053;MetaCyc: PWY-7728;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6958	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_049765270.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_049771066.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049777654.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049784446.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049784473.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049769686.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049786497.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049767487.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049775077.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049779792.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049774475.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049776924.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_049763703.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_049766767.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049780875.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049773788.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049768063.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049767048.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049783342.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049778675.1	6	KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_049765326.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049778729.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049784147.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049785294.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2691232;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948	"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Growth hormone receptor signaling";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049778621.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049766072.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049766354.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049783969.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_049763664.1	10	KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-7328	"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_049778870.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049779056.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049781322.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049767717.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049785703.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049763396.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_049787349.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049778484.1	4	MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049775378.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049784254.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049785853.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049775273.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049763097.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049780874.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049765676.1	34	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-69231;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-69273;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"HIV Transcription Initiation"
XP_049787477.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049782338.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049788337.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049775789.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049784720.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049780877.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049767791.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049783730.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049775413.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049780548.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049786069.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781121.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049775921.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049766749.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049776402.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049780900.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049786712.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049777452.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_049788394.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049765677.1	34	Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-69656;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-69202;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Cyclin E associated events during G1/S transition";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049771131.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049763111.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049777501.1	33	Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464	"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of RNA binding proteins"
XP_049763499.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049778999.1	19	Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-72706;Reactome: R-HSA-3214858;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RMTs methylate histone arginines";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation"
XP_049784274.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049784357.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
XP_049783580.1	3	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification"
XP_049766399.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_049783168.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_049779093.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787170.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049785922.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049788080.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049769643.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049766493.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049768493.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
XP_049764012.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049767471.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_049782779.1	4	Reactome: R-HSA-4755609;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87	"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis"
XP_049785078.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049776807.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049777482.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_049766914.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783623.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049778987.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049775700.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_049768294.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_049778737.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049765548.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Protein ubiquitination"
XP_049781338.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049780736.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049777627.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_049784027.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049771855.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049765571.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049777459.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049769039.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049764854.1	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_049780720.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049783830.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049787772.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766821.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049779063.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049767826.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_049763094.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049767047.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049767272.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049765485.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049777441.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049786811.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049785500.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049786574.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049787092.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049771172.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049772908.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_049778913.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_049767511.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049783182.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049786699.1	12	Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73762	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation"
XP_049775561.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049782821.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049778172.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049766928.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049773583.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_049778567.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049777504.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049775391.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_049777714.1	16	MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049779104.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049778275.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049783918.1	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Biotin transport and metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049765934.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_049786140.1	15	MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-7383	"Rubisco shunt";"Purine metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049767664.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049776251.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049783359.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049766428.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049780633.1	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049783260.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049777659.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_049780920.1	10	Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1	"RSK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Thermogenesis"
XP_049781713.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049777913.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049786981.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049773917.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049780487.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-203927	"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis"
XP_049767539.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049763084.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049778803.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049776446.1	18	KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"Ether lipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_049775579.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049785221.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774528.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049787398.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049788297.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049782992.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_049768775.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049783982.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049787603.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_049765682.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049785400.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049773786.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049764514.1	1	Reactome: R-HSA-193670	"p75NTR negatively regulates cell cycle via SC1"
XP_049773720.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049766620.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_049775947.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049778111.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049777879.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_049784764.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation"
XP_049763553.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049763354.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-2565942	"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition"
XP_049781608.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049766495.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049774917.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049764760.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049787410.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049768749.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049768844.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756	"Regulation of HSF1-mediated heat shock response";"Meiotic recombination";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation"
XP_049783034.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661	"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation"
XP_049782559.1	6	Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-418597	"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"G alpha (z) signalling events"
XP_049781481.1	12	KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756	"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation"
XP_049774134.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_049784040.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049780745.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"Neutrophil degranulation";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_049771975.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049781543.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual incision in TC-NER"
XP_049764669.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049762455.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049774295.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049762904.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049778069.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763316.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049770391.1	9	MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94	"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_049767851.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049766834.1	12	KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042	"Carbon fixation in photosynthetic organisms";"Glycolysis";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)"
XP_049779589.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049763135.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049783215.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049777324.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049787947.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_049778521.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase"
XP_049788157.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049784124.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049778790.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049786870.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710	"Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy"
XP_049767531.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690	"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"HCMV Early Events"
XP_049763028.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-6811436	"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049784852.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049786526.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049785629.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049787916.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049780006.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049784014.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049785360.1	11	KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Role of phospholipids in phagocytosis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism"
XP_049762841.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049780737.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_049773918.1	11	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049784311.1	13	MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Folate polyglutamylation";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_049771678.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049776723.1	7	MetaCyc: PWY-5514;Reactome: R-HSA-71336;MetaCyc: PWY-6906;MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_049776406.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049767074.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049787801.1	31	Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-7388;MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-6799;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-6519;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"";"Oleate biosynthesis I (plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Pederin biosynthesis";"Mupirocin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis"
XP_049775657.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049783966.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049776153.1	21	MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222	"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_049782948.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049779984.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049787192.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049783712.1	7	Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049787584.1	3	KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_049782412.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism"
XP_049785792.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
XP_049774834.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049776915.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049762498.1	24	Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190840	"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_049783464.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_049769856.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049766015.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_049769937.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049764898.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_049783917.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-3371599	"Biotin metabolism";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency"
XP_049788006.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049787607.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049779581.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049776960.1	20	KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6	"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation"
XP_049767837.1	6	Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253	"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock"
XP_049766783.1	3	KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_049779619.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049783421.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_049779003.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778887.1	6	MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165	"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049775262.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049763169.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_049771659.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049774097.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"MAP2K and MAPK activation";"Neutrophil degranulation";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049784410.1	6	KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980	"Photosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"ATP biosynthesis"
XP_049764948.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049781043.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049787473.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049787750.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049767985.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049784468.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049780879.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049765656.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049771109.1	18	KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7226	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_049777320.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049763809.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049787928.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049763517.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049776073.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049762915.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773502.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049762654.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049786670.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049777220.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049788041.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049787548.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049773015.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"MAP2K and MAPK activation";"Neutrophil degranulation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049787838.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049779445.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049779232.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049787094.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_049767010.1	15	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Processing of DNA double-strand break ends"
XP_049764977.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049787526.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049783985.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049768858.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049765879.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_049771939.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049785600.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049762298.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787631.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049770316.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Ub-specific processing proteases";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_049764924.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049769271.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049785788.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_049777480.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_049765119.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049781513.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049766980.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049765522.1	8	Reactome: R-HSA-6791462;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;MetaCyc: PWY-1861;Reactome: R-HSA-8950505	"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049784288.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418594	"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (i) signalling events"
XP_049773728.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_049777288.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049767107.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_049767707.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049767090.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049772340.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049771598.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049762643.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049783177.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049786826.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049773729.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049777485.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049785082.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049767795.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049781349.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049777312.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974	"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway"
XP_049765859.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049781307.1	12	Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-7343;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9	"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycogen synthesis";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_049767354.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049772418.1	15	MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Purine metabolism";"Rubisco shunt"
XP_049785382.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_049785769.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049762639.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_049769210.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049766454.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-141430	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_049774454.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049779006.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049775411.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049775344.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049768177.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-426496	"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs"
XP_049769367.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049775471.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049787444.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_049765390.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049764712.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049784573.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049775354.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049783448.1	4	MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049779847.1	18	MetaCyc: PWY-5913;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1	"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Arginine biosynthesis"
XP_049767177.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049774794.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049765012.1	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_049769633.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049766981.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049763531.1	4	MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049769297.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40	"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Glycolysis";"Purine metabolism";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
XP_049765124.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049787911.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049768499.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049778367.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049769547.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049770718.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049776039.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049787792.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049765921.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049787606.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049767699.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049786753.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049771239.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049778450.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049767267.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049778236.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049777300.1	8	KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_049781710.1	2	Reactome: R-HSA-499943;KEGG: 00450+1.8.1.9	"Interconversion of nucleotide di- and triphosphates";"Selenocompound metabolism"
XP_049781512.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049762750.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049766607.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049778131.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049785655.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049777059.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763490.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
XP_049779062.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049780318.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049769120.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-2173796;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6807505	"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes"
XP_049778482.1	5	Reactome: R-HSA-1234176;Reactome: R-HSA-1234174;Reactome: R-HSA-8951664;Reactome: R-HSA-8849473;Reactome: R-HSA-1234158	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cellular response to hypoxia";"Neddylation";"PTK6 Expression";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_049787646.1	7	Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69231	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1"
XP_049783216.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049770390.1	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I"
XP_049763086.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049771208.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049776678.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7340	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_049764194.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049768537.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049776778.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049774542.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy"
XP_049765761.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049772279.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_049787881.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049783818.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049777309.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Gap junction assembly";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049785515.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049778962.1	12	KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.2	"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate"
XP_049771922.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049786747.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-5685938	"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"HDR through Single Strand Annealing (SSA)"
XP_049786760.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049777505.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049782155.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049764004.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;Reactome: R-HSA-983168	"Protein ubiquitination";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049784921.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049775766.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049780668.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_049777965.1	2	KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5	"Pentose and glucuronate interconversions";"Fructose and mannose metabolism"
XP_049768305.1	30	Reactome: R-HSA-198693;KEGG: 04714+2.7.11.1;Reactome: R-HSA-389513;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614399;KEGG: 04150+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-211163;Reactome: R-HSA-8941332;Reactome: R-HSA-69202;Reactome: R-HSA-198323;Reactome: R-HSA-111447;Reactome: R-HSA-8876198;Reactome: R-HSA-1358803;Reactome: R-HSA-6804758;Reactome: R-HSA-8948751;Reactome: R-HSA-389357;Reactome: R-HSA-199418;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-9634638;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"AKT phosphorylates targets in the nucleus";"Thermogenesis";"CTLA4 inhibitory signaling";"Human immunodeficiency virus 1 infection";"Regulation of localization of FOXO transcription factors";"mTOR signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"AKT-mediated inactivation of FOXO1A";"RUNX2 regulates genes involved in cell migration";"Cyclin E associated events during G1/S transition";"AKT phosphorylates targets in the cytosol";"Activation of BAD and translocation to mitochondria";"RAB GEFs exchange GTP for GDP on RABs";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN stability and activity";"CD28 dependent PI3K/Akt signaling";"Negative regulation of the PI3K/AKT network";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_049777671.1	24	Reactome: R-HSA-202424;Reactome: R-HSA-5625740;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920	"Downstream TCR signaling";"RHO GTPases activate PKNs";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"RSK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"VEGFR2 mediated cell proliferation";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"Regulation of TP53 Degradation";"mTOR signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability"
XP_049783739.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049783587.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_049785320.1	8	KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049780911.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049788365.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049773529.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049774059.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
XP_049780944.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049782254.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049762575.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049780974.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049776263.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049775624.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049766617.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049764764.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778685.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049778607.1	7	KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Citric acid cycle (TCA cycle)";"Lysine degradation"
XP_049766580.1	7	Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625	"Synthesis of PI";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049769002.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049784444.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049788431.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049766757.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049777739.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049776982.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049770508.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049777536.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049763705.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049763975.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049784268.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049770922.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_049780498.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049763069.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049765992.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049787756.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049787270.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049767793.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049762284.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_049785459.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049769092.1	9	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection"
XP_049771938.1	4	MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662	"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049770622.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049783688.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_049767052.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049784427.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778456.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049769098.1	5	Reactome: R-HSA-111457;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-9627069	"Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity"
XP_049781411.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049787000.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889	"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes"
XP_049766020.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049782112.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049778785.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_049777892.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049780361.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15	"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism"
XP_049781761.1	3	MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway"
XP_049782894.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_049776178.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049784592.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049777368.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787309.1	10	MetaCyc: PWY-6527;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2	"Stachyose degradation";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_049766271.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_049768332.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049784550.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695	"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation"
XP_049778449.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049771619.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049781461.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049787168.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_049773596.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050	"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_049777803.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763151.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049764222.1	17	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049764316.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_049769095.1	27	Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-198323;Reactome: R-HSA-5467340;Reactome: R-HSA-75815;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5358751;Reactome: R-HSA-3371453;Reactome: R-HSA-399956;Reactome: R-HSA-196299	"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AKT phosphorylates targets in the cytosol";"AXIN missense mutants destabilize the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"mTOR signaling pathway";"B-WICH complex positively regulates rRNA expression";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"Human cytomegalovirus infection";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Thermogenesis";"Human immunodeficiency virus 1 infection";"GLI3 is processed to GLI3R by the proteasome";"S45 mutants of beta-catenin aren't phosphorylated";"Regulation of HSF1-mediated heat shock response";"CRMPs in Sema3A signaling";"Beta-catenin phosphorylation cascade"
XP_049781616.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049775376.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049787264.1	32	Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-113418	"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"FGFR2 alternative splicing";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex"
XP_049787995.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049765768.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049770761.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049788399.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049782212.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049774882.1	2	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049788392.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049784130.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049780336.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
YP_010401630.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049786714.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049763786.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049771397.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049785686.1	8	Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7187	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049773838.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049773661.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049780946.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049779385.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049764692.1	44	Reactome: R-HSA-5674135;Reactome: R-HSA-112409;Reactome: R-HSA-450341;Reactome: R-HSA-8939211;Reactome: R-HSA-5663213;Reactome: R-HSA-198753;Reactome: R-HSA-879415;Reactome: R-HSA-6802952;Reactome: R-HSA-1295596;Reactome: R-HSA-170968;Reactome: R-HSA-375165;Reactome: R-HSA-5654727;Reactome: R-HSA-881907;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-74749;Reactome: R-HSA-5673001;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2029482;Reactome: R-HSA-5654733;Reactome: R-HSA-6811558;Reactome: R-HSA-8943724;Reactome: R-HSA-456926;Reactome: R-HSA-2871796;Reactome: R-HSA-5654726;Reactome: R-HSA-445144;Reactome: R-HSA-982772;Reactome: R-HSA-5674499;Reactome: R-HSA-2559585;Reactome: R-HSA-3371453;Reactome: R-HSA-6802946;Reactome: R-HSA-8940973;Reactome: R-HSA-5668599;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-9627069;Reactome: R-HSA-5654732;Reactome: R-HSA-202670;Reactome: R-HSA-6802955;Reactome: R-HSA-9635465;Reactome: R-HSA-5675221;Reactome: R-HSA-162658;Reactome: R-HSA-9634638;Reactome: R-HSA-444257	"MAP2K and MAPK activation";"RAF-independent MAPK1/3 activation";"Activation of the AP-1 family of transcription factors";"ESR-mediated signaling";"RHO GTPases Activate WASPs and WAVEs";"ERK/MAPK targets";"Advanced glycosylation endproduct receptor signaling";"Signaling by BRAF and RAF fusions";"Spry regulation of FGF signaling";"Frs2-mediated activation";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR2 signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signal attenuation";"RAF/MAP kinase cascade";"mTOR signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of FGFR4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of PTEN gene transcription";"Thrombin signalling through proteinase activated receptors (PARs)";"FCERI mediated MAPK activation";"Negative regulation of FGFR1 signaling";"Signal transduction by L1";"Growth hormone receptor signaling";"Negative feedback regulation of MAPK pathway";"Oncogene Induced Senescence";"Regulation of HSF1-mediated heat shock response";"Signaling by moderate kinase activity BRAF mutants";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate NADPH Oxidases";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of the apoptosome activity";"Negative regulation of FGFR3 signaling";"ERKs are inactivated";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Suppression of apoptosis";"Negative regulation of MAPK pathway";"Golgi Cisternae Pericentriolar Stack Reorganization";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RSK activation"
XP_049776549.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049781793.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049779399.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049777210.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049763444.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049781228.1	19	MetaCyc: PWY-5392;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-163765;MetaCyc: PWY-5538	"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI"
XP_049787146.1	18	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7184;Reactome: R-HSA-5624138;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7226	"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Trafficking of myristoylated proteins to the cilium";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_049781392.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049786461.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049768108.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049768655.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049763159.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049786807.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049786958.1	9	KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18	"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_049784126.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049770413.1	18	MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism"
XP_049773175.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049776123.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049763770.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049784657.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_049784622.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049782151.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049777331.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049766798.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_049787771.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774804.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_049770674.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor"
XP_049776475.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049768849.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049777492.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;MetaCyc: PWY-7511	"Regulation of PTEN stability and activity";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Protein ubiquitination"
XP_049783838.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049765036.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049779013.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_049787670.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049777172.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049778378.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049766297.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049767652.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049775105.1	1	Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049777475.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049776520.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049768851.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049776681.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism"
XP_049776269.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-72163	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Protein ubiquitination";"mRNA Splicing - Major Pathway"
XP_049776896.1	8	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_049764594.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049777450.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049772132.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295	"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"MHC class II antigen presentation"
XP_049774760.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049781825.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781846.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049784599.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049775076.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049775112.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_049778108.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049775837.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049787894.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763792.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775835.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049767589.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_049764765.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049785662.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Gap junction assembly";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy"
XP_049776390.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049763258.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049775017.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049776259.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049775085.1	17	Reactome: R-HSA-69473;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648	"G2/M DNA damage checkpoint";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"Thermogenesis";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Meiotic synapsis";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049776819.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery"
XP_049777476.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049764239.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049774241.1	7	Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression"
XP_049779332.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049764689.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_049766496.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049775564.1	9	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-69183	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand"
XP_049768411.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049779064.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049777374.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049763515.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_049778830.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049777149.1	11	Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-1268020;Reactome: R-HSA-9627069	"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Mitochondrial protein import";"Regulation of the apoptosome activity"
XP_049785861.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049786303.1	6	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049778075.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049786925.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049776168.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221	"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway"
XP_049780303.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049777773.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049779393.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_049775821.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049774473.1	5	Reactome: R-HSA-446388;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-193648	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G alpha (12/13) signalling events";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"NRAGE signals death through JNK"
XP_049786022.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_049768168.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049787777.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049787159.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049780360.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15	"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism"
XP_049783445.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049777811.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763017.1	3	KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_049768072.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049776436.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049762674.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049767762.1	21	Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-975144;Reactome: R-HSA-937041;Reactome: R-HSA-1236974;Reactome: R-HSA-5357905;Reactome: R-HSA-202424;Reactome: R-HSA-5603029;Reactome: R-HSA-933543;Reactome: R-HSA-933542;Reactome: R-HSA-5684264;Reactome: R-HSA-5603027;Reactome: R-HSA-937039;Reactome: R-HSA-1810476;Reactome: R-HSA-168927;Reactome: R-HSA-9020702;Reactome: R-HSA-5602636;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091	"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IKK complex recruitment mediated by RIP1";"ER-Phagosome pathway";"Regulation of TNFR1 signaling";"Downstream TCR signaling";"IkBA variant leads to EDA-ID";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TRAF6 mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"IRAK1 recruits IKK complex";"RIP-mediated NFkB activation via ZBP1";"TICAM1, RIP1-mediated IKK complex recruitment";"Interleukin-1 signaling";"IKBKB deficiency causes SCID";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells"
XP_049785330.1	8	KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis"
XP_049775833.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Dual incision in TC-NER"
XP_049772002.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049787941.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049767288.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049763030.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049776160.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade"
XP_049765526.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_049781266.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_049773539.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049785050.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049770452.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049777471.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system"
XP_049781154.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049771708.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049787935.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_049770745.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049785029.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049773847.1	20	KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Macroautophagy";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"Relaxin signaling pathway"
XP_049779971.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049765011.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049775282.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049775964.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049774711.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049774452.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049775108.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049784317.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049787065.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_049769121.1	56	Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091	"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells"
XP_049764776.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398	"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway"
XP_049775080.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68827	"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex"
XP_049785322.1	8	KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171	"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Glycolysis"
XP_049775343.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049785892.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049770013.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events"
XP_049787930.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-5855	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_049784718.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049766494.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049768996.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049774314.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049762467.1	4	MetaCyc: PWY-5028;MetaCyc: PWY-5030;KEGG: 00340+4.2.1.49;Reactome: R-HSA-70921	"L-histidine degradation II";"L-histidine degradation III";"Histidine metabolism";"Histidine catabolism"
XP_049770843.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_049785754.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783051.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049774024.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049767195.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049786910.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049770708.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049779076.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049775786.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049767410.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049781268.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781330.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049785625.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049778604.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2	"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism"
XP_049787627.1	4	Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_049765910.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049768259.1	7	Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-983231	"HDMs demethylate histones";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production"
XP_049781504.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049768845.1	29	Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-3371511	"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Meiotic recombination";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation"
XP_049773598.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway"
XP_049778642.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049767456.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049785746.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049780671.1	14	KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4	"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PE";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism"
XP_049787602.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049784864.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049781232.1	19	Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-5172	"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)"
XP_049765911.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787618.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049765127.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049786654.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049779417.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049770919.1	6	MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3	"Guanosine nucleotides degradation III";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism"
XP_049775784.1	14	MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism"
XP_049787595.1	20	Reactome: R-HSA-499943;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380320;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7226;Reactome: R-HSA-380270;MetaCyc: PWY-7205	"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"CMP phosphorylation"
XP_049783850.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049781288.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-202433;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs"
XP_049768709.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049785045.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049775770.1	11	KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42	"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes"
XP_049765289.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514	"Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049771844.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096	"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation"
XP_049776120.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049779387.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049778807.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049764729.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049771620.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049782976.1	5	MetaCyc: PWY-7766;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7159	"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049768847.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049770960.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049770366.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049779587.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_049778988.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049788471.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049774598.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_049784369.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049785254.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-111465	"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins"
XP_049778551.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049784758.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049763208.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049778742.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER"
XP_049767310.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049764233.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_049774504.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049775965.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049777521.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Glutathione metabolism"
XP_049783567.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049763114.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049774104.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049786304.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049785344.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049785054.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049773585.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_049766223.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049776568.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049785182.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049780321.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049768052.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049784756.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049786705.1	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049772955.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049777909.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_049781538.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049786771.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049782270.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049776275.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049768029.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049764674.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049769548.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049787220.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049787943.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049765226.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049786594.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5362768	"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049783114.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049773711.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_049763774.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049766978.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394	"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER"
XP_049763268.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_049765015.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_049788191.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049777434.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_049774534.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049762985.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049787780.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049773840.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049778362.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049785413.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049764532.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049781457.1	5	KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049773111.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_049763292.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049786930.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490	"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation"
XP_049780752.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_049771389.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434	"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049786077.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049780813.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049767803.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049765207.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049769206.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049773607.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049764041.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049764238.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049772994.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049777523.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049768349.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049786462.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049787461.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049768001.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787050.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049775281.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_049773457.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049766703.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049787798.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049765279.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-8873719	"TBC/RABGAPs";"RAB geranylgeranylation"
XP_049764862.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049776991.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_049769207.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049785134.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_049785791.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049768843.1	12	KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-173599;MetaCyc: PWY-7343;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817	"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049778652.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049784184.1	11	KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-7456;MetaCyc: PWY-882;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;MetaCyc: PWY-7586	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"GDP-mannose biosynthesis";"Mannitol degradation II";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_049776856.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049767865.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389977	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway"
XP_049769571.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049787588.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049762199.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_049773772.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049784158.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_049766742.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Degradation of the extracellular matrix";"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049784790.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049782711.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049785355.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_049786653.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049774476.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049774194.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049774070.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
XP_049775984.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049772416.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049781386.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049765409.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049779375.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774446.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049781327.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049776491.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268	"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_049774101.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_049788039.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049787031.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049784537.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049773408.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049779895.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049773867.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049788324.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049783702.1	8	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6783310;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049779894.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049783202.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632	"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis"
XP_049774913.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049768164.1	12	KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-174362	"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Selenate reduction";"Sulfur metabolism";"Purine metabolism";"Selenocompound metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS"
XP_049786240.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049768257.1	7	Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-983231;Reactome: R-HSA-3214842	"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones"
XP_049767274.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049767237.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049775183.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_049786717.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049782886.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_049783488.1	7	MetaCyc: PWY-6614;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757	"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"One carbon pool by folate";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_049765507.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049777281.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049787247.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049766859.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049781289.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_049768255.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049787023.1	4	Reactome: R-HSA-204626;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Hypusine synthesis from eIF5A-lysine";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049763315.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049777516.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049783695.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049783109.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049773507.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_049787923.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049786463.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778561.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049780757.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049769254.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_049785104.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049774665.1	6	MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_049767375.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049765523.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049774096.1	9	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Neutrophil degranulation";"MAP2K and MAPK activation"
XP_049780818.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049777611.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_049772959.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202	"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition"
XP_049783378.1	10	KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6554	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_049780377.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049783383.1	12	KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7118;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1	"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Methane metabolism"
XP_049776997.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049786957.1	9	Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18	"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes"
XP_049773415.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049774118.1	29	Reactome: R-HSA-3371453;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-69541;Reactome: R-HSA-5693607;Reactome: R-HSA-6804760;KEGG: 04714+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-6803204;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-6796648;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6803207;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756	"Regulation of HSF1-mediated heat shock response";"Human immunodeficiency virus 1 infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Stabilization of p53";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Methylation";"Thermogenesis";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Human papillomavirus infection";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"mTOR signaling pathway";"Regulation of TP53 Degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_049770841.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049763368.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_049763074.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142	"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins"
XP_049763511.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785	"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome"
XP_049778360.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_049776593.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049774119.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049777228.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049782056.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_049788075.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049777043.1	16	Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-164939;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-177504	"LDL clearance";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Gap junction degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling"
XP_049776413.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049777525.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049783837.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049773156.1	17	Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-202424;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-5689880	"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ca2+ pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases"
XP_049788098.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049778366.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049777963.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049778358.1	13	MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation"
XP_049787187.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049763290.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049766491.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049786626.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049778019.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049775680.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049777055.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777489.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049785016.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049780883.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049786808.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049788045.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049765861.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049786652.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049766501.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049787221.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_049763347.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049781187.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049783131.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049775767.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049778583.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049780971.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_049787591.1	8	MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-1989781;Reactome: R-HSA-191273	"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"PPARA activates gene expression";"Cholesterol biosynthesis"
XP_049784069.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049767120.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049782222.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049764245.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049777044.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_049784725.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049784442.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049773141.1	8	Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467	"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification"
XP_049776144.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049782291.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_049786992.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049765176.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049786946.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049780912.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049787927.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049766685.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049775416.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049763021.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049780919.1	10	KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"RSK activation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Thermogenesis"
XP_049763118.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049780612.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049783528.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_049769673.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049786529.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049783052.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
YP_010401619.1	7	MetaCyc: PWY-5083;MetaCyc: PWY-3781;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105	"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Complex I biogenesis";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Respiratory electron transport"
XP_049786656.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049767467.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_049787105.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972	"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)"
XP_049776838.1	12	KEGG: 00660+4.1.3.25;MetaCyc: PWY-7118;MetaCyc: PWY-6969;MetaCyc: PWY-7854;MetaCyc: PWY-5744;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-6728;MetaCyc: PWY-5749	"C5-Branched dibasic acid metabolism";"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"Pyruvate metabolism";"L-arabinose degradation IV";"Methylaspartate cycle";"Itaconate degradation"
XP_049767276.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049780016.1	7	MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485	"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Role of phospholipids in phagocytosis"
XP_049787773.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049766560.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049785767.1	5	MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_049775923.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_049764687.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049786039.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049784142.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049779886.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049781397.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049784414.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_049787251.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049788110.1	5	Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936964	"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049769156.1	29	Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400	"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER"
XP_049772316.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049784080.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049765614.1	14	Reactome: R-HSA-72706;Reactome: R-HSA-2022377;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049787234.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049777695.1	6	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_049778498.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-1369062;Reactome: R-HSA-9029569	"HDL remodeling";"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049773112.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049783195.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex"
XP_049779096.1	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
XP_049775113.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_049774455.1	42	MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00903+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-1361;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-6883;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7778;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00360+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5789;MetaCyc: PWY-7656;MetaCyc: PWY-5109;MetaCyc: PWY-5177;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7726	"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"Androstenedione degradation";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Fatty acid salvage";"Limonene and pinene degradation";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to butanol II (engineered)";"Tryptophan metabolism";"Toluene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"2-methylpropene degradation";"Geraniol degradation";"Fatty acid degradation";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Butanoate metabolism";"Caprolactam degradation";"Pyruvate fermentation to hexanol (engineered)";"Phenylalanine metabolism";"Propanoate metabolism";"Fatty acid elongation";"alpha-Linolenic acid metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Spodoptera littoralis pheromone biosynthesis";"Fermentation to 2-methylbutanoate";"Glutaryl-coa degradation";"Fatty acid degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_049781620.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049788021.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049768166.1	12	KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4	"Purine metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Purine metabolism"
XP_049775302.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049784614.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049766784.1	6	MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174	"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
XP_049787165.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049780297.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049778735.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049780711.1	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_049779804.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_049763459.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049775412.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049773854.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049770812.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049776494.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36	"3-phosphoinositide degradation";"Rho GTPase cycle";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism"
XP_049778773.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049785513.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049781403.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049781116.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)"
XP_049783777.1	6	MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165	"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049766877.1	14	Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049779768.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049782968.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049781785.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049766908.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049777367.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774131.1	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
XP_049763172.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049762417.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049774800.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049777449.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-4615885	"HCMV Late Events";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins"
XP_049765678.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049768155.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_049777336.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049782361.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049783817.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049782336.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049763016.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049785061.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049787929.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_049767714.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049783851.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049787190.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_049774255.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049763486.1	5	KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-532668;MetaCyc: PWY-7918;Reactome: R-HSA-4793954	"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_049785534.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049773077.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049766962.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049784602.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_049779057.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049786471.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_049787418.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049773927.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049764043.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049763367.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_049765949.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049772259.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049780052.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049783709.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen degradation II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
XP_049775212.1	5	MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Stachyose degradation";"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_049775912.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_049787273.1	13	MetaCyc: PWY-6370;MetaCyc: PWY-6842;MetaCyc: PWY-2261;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00053+1.8.5.1	"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate and aldarate metabolism"
XP_049780945.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049776184.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
XP_049780786.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_049762768.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049788300.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4	"Ether lipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism"
XP_049782111.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049777337.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049767754.1	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
YP_010401620.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049773701.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_049778427.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049762706.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049780928.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049772969.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-171319	"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"UCH proteinases";"Ub-specific processing proteases";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_049764090.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_049788111.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774973.1	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
XP_049763890.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2"
XP_049780434.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049762329.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049787766.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049788009.1	7	Reactome: R-HSA-9023661;Reactome: R-HSA-9018896;Reactome: R-HSA-9018676;Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9020265	"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of D-series resolvins";"Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of aspirin-triggered D-series resolvins"
XP_049764538.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049776845.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049764649.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049763998.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049766058.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049774609.1	5	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;MetaCyc: PWY-7782;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism"
XP_049773749.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049768647.1	6	Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Rubisco shunt"
XP_049775331.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049785789.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_049784934.1	20	KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136	"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049784377.1	8	KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27	"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism"
XP_049783955.1	7	Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400	"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Degradation of DVL";"PCP/CE pathway"
XP_049764587.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049786615.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049781341.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049775976.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049776082.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049779618.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5362768	"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Neddylation";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049764880.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_049778579.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
XP_049773041.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_049774843.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049762663.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049766510.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049786891.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049778900.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_049764805.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049776825.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049766013.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049779010.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049783463.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049786715.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049763090.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049780327.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049782838.1	6	MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-4381	"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_049781452.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049778505.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049768654.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_049776360.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049776876.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049782566.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196	"G alpha (z) signalling events";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling"
XP_049776167.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-432142	"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL"
XP_049766677.1	12	MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-173599;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9	"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Galactose metabolism";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_049787546.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049782057.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049775739.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_049779002.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774530.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049767829.1	4	KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621	"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism"
XP_049784332.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049770538.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
XP_049762672.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049767590.1	3	KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism"
XP_049777493.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;MetaCyc: PWY-7511	"Regulation of PTEN stability and activity";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Protein ubiquitination"
XP_049762745.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049780386.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049785159.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049783685.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_049767059.1	12	Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049774514.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049777619.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_049784829.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_049782400.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Gap junction assembly";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049773994.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049766066.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049785027.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049762637.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_049781921.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049777056.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783869.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049784802.1	6	MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004	"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I"
XP_049775811.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049763213.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_049769214.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049767031.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049781643.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974	"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway"
XP_049787140.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049771607.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_049770844.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049788342.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049780654.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049765566.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049786153.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049784474.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_049762753.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049785107.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049784514.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049778497.1	5	Reactome: R-HSA-1234158;Reactome: R-HSA-8849473;Reactome: R-HSA-8951664;Reactome: R-HSA-1234174;Reactome: R-HSA-1234176	"Regulation of gene expression by Hypoxia-inducible Factor";"PTK6 Expression";"Neddylation";"Cellular response to hypoxia";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049771078.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049785453.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049777169.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049782611.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049780485.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049770675.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_049766990.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049774389.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049784335.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049769853.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049787139.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780433.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049783565.1	6	MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_049777878.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_049777376.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049771737.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049766571.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049778802.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049766498.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049786249.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049774941.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049765052.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049782902.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777656.1	7	KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897	"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes"
XP_049770848.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion"
XP_049766014.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049784185.1	11	MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-5659;MetaCyc: PWY-3881;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8	"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_049764261.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049773625.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_049764075.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049774562.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049767015.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049765001.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_049786984.1	10	KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23	"Galactose metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Sphingolipid metabolism"
XP_049782973.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_049767745.1	7	MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483191	"Plasmalogen biosynthesis";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC"
XP_049777643.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049779092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780949.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049770564.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049784623.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049773937.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837	"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation"
XP_049771429.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049785112.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049787610.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049777458.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049773794.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049784696.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-6790901	"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol"
XP_049765126.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049781029.1	8	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-912446	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination"
XP_049778403.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_049774160.1	7	Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659	"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-mannose biosynthesis"
XP_049774857.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049763742.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049785799.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049771361.1	56	Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895	"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis"
XP_049785547.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049788146.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049779746.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049774790.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049783715.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_049787922.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049786986.1	10	KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Sphingolipid metabolism";"Other glycan degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_049766582.1	7	Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625	"Synthesis of PI";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049778509.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049770625.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049787428.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049766989.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049774664.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049788100.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049788158.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049787857.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049764224.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049764223.1	17	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049780673.1	14	KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-7782	"Sphingolipid metabolism";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Glycerolipid metabolism";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PE";"Plasmalogen biosynthesis"
XP_049785728.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781987.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049766916.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049780040.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049782695.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049773863.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049787163.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049765809.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_049777894.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_049766581.1	7	MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226	"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI"
XP_049783987.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774835.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049766016.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049785103.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049776546.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049787454.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049783027.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049773404.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766903.1	5	KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-6798695	"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation"
XP_049787186.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049782750.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049783553.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA"
XP_049781855.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780862.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049763497.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049783190.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049783108.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049781489.1	14	MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049781399.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049786831.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049763446.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049767845.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049777291.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049765527.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_049766751.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049774695.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049766933.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049783836.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049766982.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787987.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049784356.1	3	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism"
XP_049776613.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049774951.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049783045.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049785777.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049776078.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_049787280.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049777356.1	4	MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_049786387.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049783845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049787430.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049768405.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049773610.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_049786994.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_049780302.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049771452.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783865.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049787942.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_049784286.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-392451	"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"G-protein activation";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma"
XP_049778555.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_049773212.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049777513.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049783280.1	7	MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-5695	"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation"
XP_049776996.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049784299.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049767028.1	31	MetaCyc: PWY-6519;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-8012;MetaCyc: PWY-5994;MetaCyc: PWY-5966-1;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-5989;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-5147;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-8047;MetaCyc: PWY-7746	"8-amino-7-oxononanoate biosynthesis I";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Mupirocin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Pederin biosynthesis";"";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis"
XP_049775237.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049783622.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_049777469.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation"
YP_010401631.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049773885.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_049769894.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049777509.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049779588.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
XP_049778573.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049786473.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_049775730.1	11	Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-9013695	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_049762642.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049776293.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049771799.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049763813.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049783265.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049780968.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049788314.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049785099.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_049776990.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049781231.1	19	Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5172;MetaCyc: PWY-5392;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00660+6.2.1.5	"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"C5-Branched dibasic acid metabolism"
XP_049764826.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049784148.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049785015.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049771806.1	6	MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165	"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049775668.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049773520.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049778726.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049777327.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049781055.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049763085.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049784619.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049776656.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049775645.1	17	Reactome: R-HSA-1912408;Reactome: R-HSA-113501;Reactome: R-HSA-6804114;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-1538133;Reactome: R-HSA-2559580;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-9616222;Reactome: R-HSA-111448;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-69205	"Pre-NOTCH Transcription and Translation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"G0 and Early G1";"Oxidative Stress Induced Senescence";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional regulation of granulopoiesis";"Activation of NOXA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"G1/S-Specific Transcription"
XP_049764787.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_049786806.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049783179.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049775900.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049773516.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049778564.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049764806.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-8001	"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_049767123.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049786667.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049785706.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049766879.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049788097.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781537.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049768900.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5358565	"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Meiotic recombination";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049763571.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049783358.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049766539.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77588;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-9010553;Reactome: R-HSA-8851708;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-975956;Reactome: R-HSA-6803529;Reactome: R-HSA-159236;Reactome: R-HSA-72086	"Transport of the SLBP independent Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Regulation of expression of SLITs and ROBOs";"Signaling by FGFR2 IIIa TM";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"FGFR2 alternative splicing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Capping"
XP_049781709.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049772388.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049787484.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774786.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_049765765.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049783212.1	8	Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049774809.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049775732.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049774883.1	6	Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Mitochondrial protein import"
XP_049765144.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends"
XP_049782050.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049765498.1	10	MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;Reactome: R-HSA-1989781	"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"PPARA activates gene expression"
XP_049787764.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049778448.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049777891.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_049786535.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049774328.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049762993.1	14	Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_049784763.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161	"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation"
XP_049786935.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_049786757.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Intraflagellar transport";"MHC class II antigen presentation"
XP_049764604.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049788273.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049767755.1	4	MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922	"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_049779334.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049777362.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049784326.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049787992.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049778210.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5339716	"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_049774099.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049781680.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049777968.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_049787986.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049780577.1	5	KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_049775808.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049785391.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049774536.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049767672.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-73933	"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)"
XP_049764078.1	13	MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049767339.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049787294.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049778697.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049787567.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049767293.1	17	KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1	"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_049786659.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049786247.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049764350.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_049765596.1	12	MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5872;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-6708	"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_049782707.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049781534.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-174430	"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation"
XP_049773945.1	4	MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_049780794.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049766453.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_049773978.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049773184.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049764298.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190861	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Gap junction assembly"
XP_049778129.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049766854.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049771011.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049782224.1	5	Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
XP_049763096.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049769647.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-429947	"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_049782872.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049763234.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049779598.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049763735.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049770811.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049783191.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-7587;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA"
XP_049783035.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049784606.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049784740.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_049785110.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049773944.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049773456.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049767002.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049785168.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531	"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus"
XP_049763116.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049780174.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049765794.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049773721.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049783998.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049779320.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049785025.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049783776.1	6	MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_049774745.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049776080.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049763054.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-9648025;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion"
XP_049762615.1	5	Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-901042	"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle"
XP_049785514.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049785178.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049767642.1	18	KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4	"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Ether lipid metabolism"
XP_049788174.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_049777189.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049767445.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049766746.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049768588.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049766224.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049787118.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049775236.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049785661.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Kinesins";"Separation of Sister Chromatids";"MHC class II antigen presentation"
XP_049781258.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_049776389.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049778073.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049768750.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049783819.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049767483.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049788384.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049777378.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781035.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049764287.1	10	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049771188.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049764234.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049782017.1	4	KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate"
XP_049782298.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_049777698.1	6	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression"
XP_049777140.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049778868.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049772457.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049786692.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049773455.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_049777053.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049773400.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049788312.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049764740.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_049779394.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049766456.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049771007.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049764112.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049775822.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049780323.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049763665.1	16	Reactome: R-HSA-75955;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-8951664	"RNA Polymerase II Transcription Elongation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation"
XP_049782988.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049785860.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049777702.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049782148.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049782114.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049783758.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_049784598.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049784097.1	18	MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7224;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049785753.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049776349.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway"
XP_049772972.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049767595.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049778933.1	30	Reactome: R-HSA-2644607;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-69231;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702	"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Cyclin D associated events in G1";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Neddylation";"Prolactin receptor signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling"
XP_049777442.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049781964.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049781060.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049776407.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049784539.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049767286.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049770618.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049783629.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049766674.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049779975.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049786506.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049772271.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049769896.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049784138.1	15	Reactome: R-HSA-8863795;Reactome: R-HSA-9665247;Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665233;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246	"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib"
XP_049764911.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049771616.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049780002.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049769273.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049766461.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702	"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Neddylation";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Interleukin-1 signaling"
XP_049777543.1	29	Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6781827	"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"mRNA Capping";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049782395.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775480.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049783540.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling"
XP_049783898.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import"
XP_049768258.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"HDMs demethylate histones"
XP_049784919.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049783361.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049787994.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049778076.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049775443.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_049776205.1	13	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of TP53 Degradation";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_049784093.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_049784851.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007	"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)"
XP_049786233.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049773950.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049778640.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049765381.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108	"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis"
XP_049781679.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049779228.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049788338.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049780991.1	5	Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049777670.1	24	Reactome: R-HSA-165158;Reactome: R-HSA-6804757;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-5625740	"Activation of AKT2";"Regulation of TP53 Degradation";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"G beta:gamma signalling through PI3Kgamma";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Integrin signaling";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"RSK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"RHO GTPases activate PKNs"
XP_049783046.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049763365.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_049784068.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049784428.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049783716.1	6	MetaCyc: PWY-6123;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism"
XP_049780518.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049781787.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049784213.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049784861.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Insulin receptor recycling";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_049762590.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling"
XP_049766442.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_049771484.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775268.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049788438.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781420.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049776249.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049766755.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049779225.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049775962.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049773712.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049784135.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049788374.1	52	Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-76066;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-73762;Reactome: R-HSA-5601884;Reactome: R-HSA-72163	"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"FGFR2 alternative splicing";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway"
XP_049781531.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049788250.1	13	Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-1442490	"Integrin cell surface interactions";"Extracellular matrix organization";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"ECM proteoglycans";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Collagen degradation"
XP_049768585.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_049769266.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049777649.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049768587.1	5	Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210	"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049785010.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049780017.1	7	Reactome: R-HSA-1483148;MetaCyc: PWY-7039;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166	"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA"
XP_049783839.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049762829.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049783659.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049783355.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049780582.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-5673001	"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade"
XP_049766653.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049773158.1	17	Reactome: R-HSA-9014325;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956	"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Ca2+ pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049783507.1	18	KEGG: 00020+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;Reactome: R-HSA-6783984;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00260+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00310+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Glycine degradation";"Propanoate metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Glycine, serine and threonine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Lysine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)"
XP_049780896.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049775991.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
YP_010401624.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049781385.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049784925.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049770921.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)"
XP_049786680.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049765841.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049776261.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049776260.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049770861.1	6	Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"MET activates PTK2 signaling";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049771547.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049769108.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049782197.1	6	Reactome: R-HSA-9640463;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Wax biosynthesis";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
XP_049781460.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049768146.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049775621.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049767604.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049778418.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049764260.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049774532.1	3	MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049776036.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049787119.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049784742.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049775375.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049770633.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049764005.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling"
XP_049779354.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049777205.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049784726.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049785555.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049762870.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049778952.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049766083.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049787828.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049766739.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049785093.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049783763.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964038	"Chylomicron assembly";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"LDL remodeling";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"LDL clearance"
XP_049772429.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049763500.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049777310.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049762820.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049773422.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2206305	"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D"
XP_049765881.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049773209.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049783082.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049779324.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_049763194.1	14	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-434316;MetaCyc: PWY-7039;Reactome: R-HSA-418217;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-500657;Reactome: R-HSA-4086398	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"G beta:gamma signalling through PLC beta";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"Ca2+ pathway"
XP_049776412.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049775761.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049763646.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049766517.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049779770.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_049783245.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049764464.1	8	MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;Reactome: R-HSA-73614;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199	"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage"
XP_049770846.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-606279	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049779260.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049786908.1	4	KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;Reactome: R-HSA-917937;MetaCyc: PWY-5874	"Porphyrin and chlorophyll metabolism";"Heme degradation";"Iron uptake and transport";"Heme degradation I"
XP_049763525.1	4	MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049773216.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_049787892.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-6859	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis"
XP_049785673.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049784404.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049771718.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049784053.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_049767308.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049769324.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049774912.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049767501.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress"
XP_049768034.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_049767008.1	26	Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-6804114;Reactome: R-HSA-8866654;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-4615885;Reactome: R-HSA-69183;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-6782135;Reactome: R-HSA-174417	"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA replication proteins";"Processive synthesis on the lagging strand";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis"
XP_049781570.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049775620.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Macroautophagy"
XP_049775377.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049762246.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049782305.1	3	MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099	"L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling"
XP_049784271.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049775119.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049778116.1	10	KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411	"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)"
XP_049773771.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049776408.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049781325.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_049787475.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785049.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049762437.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049787586.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049777812.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049786698.1	12	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049765842.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049762851.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695	"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation"
XP_049783589.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049782766.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049776822.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049765267.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049767900.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049784029.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049783684.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_049776854.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049784565.1	17	Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8951664	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation"
XP_049779238.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049782396.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483	"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Recycling pathway of L1";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs"
XP_049783741.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049787339.1	21	MetaCyc: PWY-7219;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198	"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049764268.1	6	MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731	"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III"
XP_049781380.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049786772.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria"
XP_049773864.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049780934.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-381042	"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression"
XP_049764779.1	22	Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-7592;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-8041;MetaCyc: PWY-6958	"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_049775110.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049763109.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049765988.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049780652.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049776034.1	9	KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902	"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)"
XP_049779005.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049777651.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049773954.1	9	MetaCyc: PWY-6901;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-7003;Reactome: R-HSA-70171	"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis"
XP_049784255.1	5	KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis"
XP_049784850.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007	"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)"
XP_049774700.1	9	KEGG: 00350+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00401+2.6.1.5	"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Novobiocin biosynthesis"
XP_049772231.1	7	MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2	"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049784621.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049769199.1	9	KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-196780;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1	"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes"
XP_049783264.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049782773.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049766671.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049775379.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049785357.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049787120.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049764676.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049772096.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049763845.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049764089.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257	"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN"
XP_049785796.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049773996.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049774032.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_049764490.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049779221.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049776832.1	12	KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7854;MetaCyc: PWY-5744;MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-6728;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Methylaspartate cycle";"Pyruvate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV"
XP_049785077.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049788478.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049784398.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049778677.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049784848.1	20	Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136	"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049775066.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049779095.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049782230.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-400206	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"Regulation of lipid metabolism by PPARalpha"
XP_049773796.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_049766448.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174184	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_049772415.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049777642.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049782564.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049780807.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049774797.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049786810.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049775691.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049763171.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049775086.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049766437.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_049777037.1	11	MetaCyc: PWY-6608;MetaCyc: PWY-5381;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5695	"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation"
XP_049778683.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049782136.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_049787614.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_049777294.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049774874.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189	"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recycling pathway of L1";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins"
XP_049770744.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049777028.1	18	MetaCyc: PWY-7511;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-69473	"Protein ubiquitination";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Processing of DNA double-strand break ends";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint"
XP_049770532.1	6	MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_049784440.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049787183.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783028.1	6	MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317	"Stachyose degradation";"Galactose metabolism";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_049787377.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049766298.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049773187.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049785003.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion"
XP_049784719.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049769046.1	17	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-3270619;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-1834949;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRF3-mediated induction of type I IFN";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Cytosolic sensors of pathogen-associated DNA";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks"
XP_049762799.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773131.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049764028.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774802.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_049768497.1	9	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis"
XP_049777379.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049786087.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049783261.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049787279.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049780176.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049764246.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049778739.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049771710.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049782798.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049773045.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049783773.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608	"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Platelet degranulation"
XP_049775111.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_049779368.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766025.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049781227.1	19	KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5392;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690	"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"C5-Branched dibasic acid metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)"
XP_049782097.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049766761.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049782089.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049766021.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049781535.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049765230.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049769257.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049766722.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049777167.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049765964.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766019.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049766793.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049783906.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import"
XP_049767494.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049769749.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_049784493.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049779865.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049774993.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049782208.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_049774914.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049765990.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049784516.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049785252.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5693607	"Ub-specific processing proteases";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends"
XP_049780735.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144	"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049780792.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049767588.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049780364.1	10	MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049776058.1	12	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-5250924	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"B-WICH complex positively regulates rRNA expression"
XP_049776079.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766023.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_049763474.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049785138.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049774525.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049785768.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049773542.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_049767229.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049779124.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049787520.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_049769215.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049787810.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049766944.1	18	KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"Ether lipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_049786776.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049768344.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049764705.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport"
XP_049765010.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049771817.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049773128.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049762217.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049764236.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049782376.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_049778749.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_049775551.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049763346.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049785554.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049787417.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049773173.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049783681.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection"
XP_049777292.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049764241.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_049785379.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049776272.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049767809.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049773718.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049787998.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050	"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_049778778.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049762200.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_049784669.1	9	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04151+2.7.11.1;Reactome: R-HSA-446353;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"PI3K-Akt signaling pathway";"Cell-extracellular matrix interactions";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049772273.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049779055.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049784574.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049775251.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049779103.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"mTOR signaling pathway"
XP_049783624.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049765943.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040	"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis"
XP_049767675.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-110357	"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1"
XP_049772178.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-975634	"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport"
XP_049769895.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049787880.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049775445.1	58	Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-5689901;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Metalloprotease DUBs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state"
XP_049769707.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049787648.1	7	Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69231	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1"
XP_049771445.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)"
XP_049776713.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049786402.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049778565.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049783144.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049787931.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5872	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_049772427.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049788265.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049762421.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049785164.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049765638.1	5	KEGG: 00983+2.4.2.4;Reactome: R-HSA-73621;MetaCyc: PWY-7181;KEGG: 00240+2.4.2.4;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_049772521.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049778101.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049778747.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049767294.1	17	KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;KEGG: 00061+6.4.1.2	"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Carnitine metabolism";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis"
XP_049782337.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049763132.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049763990.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049763313.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049773061.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049768348.1	9	KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049787587.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049776242.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049780565.1	10	MetaCyc: PWY-7510;MetaCyc: PWY-6322;MetaCyc: PWY-7769;MetaCyc: PWY-7419;MetaCyc: PWY-6839;MetaCyc: PWY-8067;MetaCyc: PWY-6682;KEGG: 00998+5.4.2.9;KEGG: 00440+5.4.2.9;MetaCyc: PWY-5757	"Rhizocticin A and B biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Phosalacine biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"2-aminoethylphosphonate biosynthesis";"Methylphosphonate biosynthesis";"Dehydrophos biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Phosphonate and phosphinate metabolism";"Fosfomycin biosynthesis"
XP_049763914.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049768649.1	29	Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-3371453	"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response"
XP_049773403.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049776631.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049768247.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049767825.1	6	Reactome: R-HSA-5083632;MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_049780583.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719	"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors"
XP_049775481.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049770623.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049776543.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049780750.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049786926.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049778206.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049773406.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766390.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049786469.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049766222.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049777906.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;MetaCyc: PWY-7980	"Photosynthesis";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"ATP biosynthesis"
XP_049778813.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049781044.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840	"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_049781664.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism"
XP_049776652.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049787131.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049773903.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049784091.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_049780483.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049766825.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation"
XP_049769258.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049786128.1	8	KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_049780947.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049771621.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049785611.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763	"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction"
XP_049787870.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049763833.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049776888.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049787932.1	12	MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5872;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-7230;MetaCyc: PWY-5857	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_049780950.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049766248.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049763491.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68827	"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex"
XP_049787087.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049783429.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049784441.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049785580.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_049780000.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049774859.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049764104.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049770629.1	3	Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049779748.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783727.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049769099.1	5	Reactome: R-HSA-111457;Reactome: R-HSA-111469;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111463	"Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs"
XP_049782686.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049777544.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049783514.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049787774.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778455.1	17	Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-69166	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate"
XP_049780501.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049785854.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049776391.1	15	Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167243	"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery"
XP_049783092.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577	"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21"
YP_010401623.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049785253.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-111465	"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins"
XP_049779625.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049781064.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049783686.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_049765645.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787592.1	8	MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-1989781;Reactome: R-HSA-191273	"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"PPARA activates gene expression";"Cholesterol biosynthesis"
XP_049779492.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049770715.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_049778606.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049780384.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049770785.1	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049777890.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049778983.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049770239.1	19	Reactome: R-HSA-8950505;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-5663220;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-3928662;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-428543;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"RHO GTPases Activate Formins";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"EPHB-mediated forward signaling";"Myogenesis";"EGFR downregulation";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1"
XP_049786913.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049779518.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049765123.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_049784402.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049771711.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049785385.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049785939.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-9616222	"Transcriptional regulation of white adipocyte differentiation";"Transcriptional regulation of granulopoiesis"
XP_049780748.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049762630.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049775970.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation"
XP_049782406.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049762726.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049768035.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049762609.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049767404.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049762950.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049780526.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049769641.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049764367.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049764235.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049781711.1	3	MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262	"L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis"
XP_049788109.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_049775818.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049786720.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049788267.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049785351.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049778004.1	7	KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049774841.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049763209.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049784355.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049763776.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049763960.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049784081.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049783197.1	2	KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19	"Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism"
XP_049788465.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049762390.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049766084.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049776639.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-167287	"Formation of RNA Pol II elongation complex";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery"
XP_049764098.1	5	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.21;MetaCyc: PWY-7199;Reactome: R-HSA-69205;KEGG: 00240+2.7.1.21	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine metabolism"
XP_049769270.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049777293.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049779970.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049763526.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_049762529.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049780970.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049772267.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases"
XP_049784810.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049771930.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_049778698.1	4	MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
XP_049780811.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049787830.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049786663.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049763144.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049780759.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049763808.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049779094.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049766525.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049776420.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049787313.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049785179.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049764292.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049779372.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778768.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049767051.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049763716.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_049764621.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_049785208.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049763255.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049767270.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049781324.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7036	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_049774770.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049787093.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049772244.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049775382.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049781387.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049775517.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6	"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Purine metabolism"
XP_049781473.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression"
XP_049786845.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis"
XP_049771089.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049782744.1	13	Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2029485	"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Regulation of insulin secretion";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis"
XP_049766063.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_049770292.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049788402.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049775972.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation"
XP_049763360.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049773137.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049781488.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_049781953.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_049763000.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II"
XP_049765276.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041	"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle"
XP_049763134.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049785163.1	6	Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049764341.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049773407.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049768276.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049780576.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049763676.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_049782943.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049775314.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049773215.1	4	MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_049773878.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049783848.1	5	Reactome: R-HSA-4420097;Reactome: R-HSA-5668599;Reactome: R-HSA-1222556;Reactome: R-HSA-1236973;Reactome: R-HSA-3299685	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate NADPH Oxidases";"ROS and RNS production in phagocytes";"Cross-presentation of particulate exogenous antigens (phagosomes)";"Detoxification of Reactive Oxygen Species"
XP_049773920.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_049787474.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774808.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049777635.1	17	MetaCyc: PWY-4202;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;MetaCyc: PWY-6609;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-5695	"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage III";"Purine catabolism";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation"
XP_049774839.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049780517.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049764240.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049773038.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049774960.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_049783047.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049777240.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049765917.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;Reactome: R-HSA-73817	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
XP_049785186.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049778149.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049767197.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773421.1	5	Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-432720;Reactome: R-HSA-2206305	"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D"
XP_049766053.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049779946.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049772258.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049782103.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-2129379	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres"
XP_049786708.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation"
XP_049781609.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049777650.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049774391.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049774840.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049774394.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049770401.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049785048.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049767066.1	10	KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)"
XP_049774467.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049784538.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049778967.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949	"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin"
XP_049782660.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049765248.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049782612.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049770091.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049764491.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049788095.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049764684.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049773654.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616	"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049785702.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049781776.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_049781663.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555	"Regulation of signaling by CBL";"MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1"
XP_049765591.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049765003.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation"
XP_049781466.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049766992.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049764722.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049786828.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049781352.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049780916.1	10	KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239	"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"RSK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1"
XP_049767997.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation"
XP_049787479.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049780042.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049777633.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-110314	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049765137.1	6	KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7077;KEGG: 00520+3.5.1.25	"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049768274.1	5	Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948	"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants"
XP_049787307.1	10	Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7328	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Stachyose degradation";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_049783255.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049769032.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778009.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_049784375.1	8	MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901	"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation"
XP_049779379.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408	"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation"
XP_049777332.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049774360.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation"
XP_049785692.1	6	Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;MetaCyc: PWY-7391	"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)"
XP_049777197.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049768597.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049774863.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049780749.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049778454.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049778356.1	13	MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation"
XP_049766807.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_049784989.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049788022.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049785012.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_049775809.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049765886.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049766054.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778425.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049786650.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049765158.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049766027.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_049778596.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_049763607.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049778571.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049780893.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049769096.1	9	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Thermogenesis"
XP_049786987.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_049779954.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049765280.1	4	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;KEGG: 00531+2.3.1.78;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation"
XP_049788167.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049764314.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049767046.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049776454.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_049786281.1	7	MetaCyc: PWY-7158;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1	"L-phenylalanine degradation V";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_049778306.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049772437.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049777051.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049786300.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049787343.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_049785518.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049780632.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis"
XP_049770495.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049767761.1	21	Reactome: R-HSA-5357905;Reactome: R-HSA-1236974;Reactome: R-HSA-937041;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-933543;Reactome: R-HSA-5603029;Reactome: R-HSA-202424;Reactome: R-HSA-168927;Reactome: R-HSA-5603027;Reactome: R-HSA-1810476;Reactome: R-HSA-937039;Reactome: R-HSA-5684264;Reactome: R-HSA-933542;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5602636	"Regulation of TNFR1 signaling";"ER-Phagosome pathway";"IKK complex recruitment mediated by RIP1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"IkBA variant leads to EDA-ID";"Downstream TCR signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"RIP-mediated NFkB activation via ZBP1";"IRAK1 recruits IKK complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TRAF6 mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"IKBKB deficiency causes SCID"
XP_049762518.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049765617.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049787636.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049762656.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049777840.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781230.1	19	KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;Reactome: R-HSA-163765;MetaCyc: PWY-5392;MetaCyc: PWY-5172;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105	"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis"
XP_049784420.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049764293.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049775853.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049786413.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049769640.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-166208	"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling"
XP_049771418.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049768618.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049778196.1	5	KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-193048;Reactome: R-HSA-446199;Reactome: R-HSA-4755579	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_049784620.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049773793.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049774288.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859	"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly"
XP_049783406.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_049768860.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_049786709.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049785856.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049782104.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049777977.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049767477.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049779405.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049775118.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_049766820.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_049773824.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159230	"HCMV Early Events";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_049777559.1	10	MetaCyc: PWY-3841;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7199;Reactome: R-HSA-69205;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184	"Folate transformations II (plants)";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049771544.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049777694.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_049768180.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049782735.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049768334.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049786664.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049779036.1	3	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_049776809.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049764665.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049780018.1	7	KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PA"
XP_049780559.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049787966.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049784333.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049784086.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049765380.1	4	KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate"
XP_049776682.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7858	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II"
XP_049785030.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049777380.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049785718.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049776091.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049768861.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins"
XP_049763361.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049785464.1	5	Reactome: R-HSA-6804756;Reactome: R-HSA-936440;Reactome: R-HSA-5668599;Reactome: R-HSA-1169408;Reactome: R-HSA-6811555	"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases";"ISG15 antiviral mechanism";"PI5P Regulates TP53 Acetylation"
XP_049787593.1	8	Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524	"Cholesterol biosynthesis";"Mevalonate pathway I";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)"
XP_049764652.1	4	Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_049788373.1	52	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-5601884;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-167243;Reactome: R-HSA-76066;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-72086	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"FGFR2 alternative splicing";"mRNA Capping"
XP_049787034.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049775269.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_049783483.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-500657	"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors"
XP_049773983.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049764714.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049766282.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049777499.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-193692	"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR"
XP_049765776.1	13	Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-437239	"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1"
XP_049780279.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049778649.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049769165.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695	"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Neutrophil degranulation"
XP_049766721.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_049787765.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049767338.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049770143.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-200425	"TP53 Regulates Metabolic Genes";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism"
XP_049763076.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049780587.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802952	"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions"
XP_049773833.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049765172.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049765083.1	4	Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping"
XP_049784463.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049779391.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049774920.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459	"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049772469.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_049784728.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049784403.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049766824.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049764412.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049776545.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049774871.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049786909.1	4	MetaCyc: PWY-5874;Reactome: R-HSA-917937;Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18	"Heme degradation I";"Iron uptake and transport";"Heme degradation";"Porphyrin and chlorophyll metabolism"
XP_049775856.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_049788179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049764155.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049777373.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049775117.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049762635.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_049781038.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049783422.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049780003.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049785744.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049786570.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049773414.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_049773832.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049787715.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049788494.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049763251.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_049765863.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049767718.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049777451.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049773928.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Neutrophil degranulation";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_049771166.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049783019.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_049777851.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049764596.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049766012.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049780005.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049763345.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049784320.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy"
XP_049766960.1	11	Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5693579	"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange"
XP_049779817.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_049763330.1	18	KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-561	"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Methane metabolism";"Methylaspartate cycle";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_049787532.1	11	KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9	"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine metabolism"
XP_049773792.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049777804.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049784496.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049766961.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050	"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_049782691.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049776901.1	8	KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;Reactome: R-HSA-6787639;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-5740;MetaCyc: PWY-7573	"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis"
XP_049762743.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049784129.1	7	Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750	"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Transcriptional Regulation by E2F6"
XP_049766451.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-176407	"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049784856.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049765834.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049775244.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049766819.1	3	MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17	"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism"
XP_049787997.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049776295.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049786014.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049774836.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049779007.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049762384.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation"
XP_049772966.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_049780471.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049784723.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049770936.1	1	Reactome: R-HSA-156581	"Methylation"
XP_049777360.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049763910.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049769642.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-9010553	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs"
XP_049783760.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049773029.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049784416.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049785303.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049764894.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049766511.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049778827.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780273.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049787416.1	18	KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049765947.1	4	MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072	"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization"
XP_049786296.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049768000.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049772172.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049763051.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049785038.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049786606.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049777624.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049784528.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6	"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism"
XP_049781425.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
XP_049770533.1	6	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I"
XP_049784554.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-499943;Reactome: R-HSA-6798695	"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation"
XP_049763663.1	10	MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism"
XP_049776926.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049783834.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049766586.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_049777486.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049788321.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049762398.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049776254.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049777897.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_049774772.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049762801.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049782215.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_049762604.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049768997.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049765288.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
XP_049763442.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049776450.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049780663.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049777478.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049777491.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049776550.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049763670.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049764429.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049784329.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049788042.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049784658.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression"
XP_049773829.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049767859.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049769948.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049767060.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"Neddylation";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049786802.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049766504.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049776840.1	12	MetaCyc: PWY-5749;MetaCyc: PWY-6728;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7854;MetaCyc: PWY-5744;MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25	"Itaconate degradation";"Methylaspartate cycle";"Pyruvate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism"
XP_049784048.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049774907.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_049785762.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049769852.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049777993.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_049767340.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049773914.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049766502.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049780918.1	10	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"RSK activation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049788099.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783074.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049774722.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049785566.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049785267.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049765637.1	5	KEGG: 00240+2.4.2.4;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.4;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_049782979.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049774939.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_049776870.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049773710.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049778844.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_049778457.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_049784057.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
XP_049767373.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049765037.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049781589.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049783457.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049786949.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049779848.1	18	KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1	"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_049784615.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049779830.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_049786983.1	10	KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23	"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Other glycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049778106.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049780886.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049785026.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_049786735.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049768560.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_049786492.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049778459.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049762158.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049777266.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_049781830.1	5	MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049763743.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049785627.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049766579.1	7	Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625	"Synthesis of PI";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049764592.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049770940.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049775946.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049776088.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_049768707.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_049766858.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049780510.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_049774238.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049786799.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049785313.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049782738.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638	"Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_049775099.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_049766720.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049766701.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253	"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock"
XP_049782137.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_049774162.1	7	MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8	"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_049784022.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938	"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Retinoid metabolism and transport";"LDL clearance";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"LDL remodeling";"Scavenging by Class F Receptors";"VLDL clearance";"VLDL assembly";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand"
XP_049766081.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_049783990.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049784151.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_049770732.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049763447.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049785175.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"Protein ubiquitination";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_049786962.1	9	MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590	"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation"
XP_049769253.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049782506.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049764431.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049775022.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049769001.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049778587.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049763435.1	4	Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-3232142	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"SUMOylation of ubiquitinylation proteins"
XP_049776176.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049782682.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049788346.1	13	Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Integrin cell surface interactions";"Extracellular matrix organization";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"ECM proteoglycans";"Laminin interactions";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_049766333.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049767290.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049762746.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049765829.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049770579.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049776883.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_049773174.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049782199.1	6	Reactome: R-HSA-9640463;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"Wax biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
XP_049779692.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049784775.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049778439.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049778263.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049776075.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049763170.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049781789.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049783606.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049782433.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049764160.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport"
XP_049784370.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_049784497.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049783086.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049775967.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049781603.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049787265.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049770978.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049784506.1	5	Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172	"VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions"
XP_049783554.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049774837.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049787314.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780594.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955	"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049778975.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049787512.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049784187.1	11	MetaCyc: PWY-6992;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-5659	"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis"
XP_049785102.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049776467.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949	"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA"
XP_049763722.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049764095.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049763175.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049785325.1	8	KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1	"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis"
XP_049779009.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049767232.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation"
XP_049763933.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049762995.1	14	Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism"
XP_049767316.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783583.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049780509.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Chromatin modifying enzymes";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049786580.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049786762.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049784415.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049784020.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964038	"Chylomicron assembly";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"VLDL assembly";"VLDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL remodeling";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"LDL clearance"
XP_049775760.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049783384.1	12	MetaCyc: PWY-7118;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133	"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Methane metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis"
XP_049768367.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049774158.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7586	"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_049779976.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-165054	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA"
XP_049772974.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049776553.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049786131.1	8	KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Pyruvate metabolism"
XP_049787823.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049762842.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690	"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Early Events"
XP_049777202.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_049775456.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049773172.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049780525.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049781172.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049787888.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049778204.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-141444	"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049770849.1	9	MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5789	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_049778614.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049764799.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049767113.1	25	Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736	"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
XP_049776442.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049764584.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049766759.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049774565.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049779611.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049780324.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049775757.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049767786.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049764856.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049776922.1	5	KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_049769685.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049765486.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_049783666.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049783639.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049784310.1	13	MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_049780363.1	10	MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)"
XP_049767548.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049764671.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049778235.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049784309.1	13	KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-2201	"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Folate transformations I"
XP_049774409.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049787973.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049785101.1	4	Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling"
XP_049780898.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049780809.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049763296.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049780502.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049778368.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049776003.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418594	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events"
XP_049781379.1	12	KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-601	"Cysteine and methionine metabolism";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan"
XP_049778114.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049780027.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049769140.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049783757.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049773865.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_049762994.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism"
XP_049788038.1	17	Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167246;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-75955;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167238;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200	"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Th1 and Th2 cell differentiation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"T cell receptor signaling pathway";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049777029.1	18	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;MetaCyc: PWY-7511	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Protein ubiquitination"
XP_049771126.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049778234.1	8	KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16	"Glycerophospholipid metabolism";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway"
XP_049768739.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049776089.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049775218.1	40	Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-5578749	"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"FGFR2 alternative splicing";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs"
XP_049777446.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783921.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15	"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism"
XP_049774795.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049762538.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049773153.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049784644.1	6	MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism"
XP_049785181.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049784649.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049771485.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049770405.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049776658.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049778253.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024	"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events"
XP_049787921.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049765640.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-2206291;Reactome: R-HSA-2024096	"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation"
XP_049769974.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of PTEN stability and activity"
XP_049788131.1	2	Reactome: R-HSA-901032;MetaCyc: PWY-7511	"ER Quality Control Compartment (ERQC)";"Protein ubiquitination"
XP_049781465.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049767846.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049765245.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049766876.1	14	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-6798695;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-1251985;Reactome: R-HSA-205043	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Neutrophil degranulation";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus"
XP_049768715.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049766681.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049764525.1	43	Reactome: R-HSA-9648025;Reactome: R-HSA-180024;Reactome: R-HSA-69273;Reactome: R-HSA-5358749;Reactome: R-HSA-2565942;Reactome: R-HSA-6811558;Reactome: R-HSA-9634600;Reactome: R-HSA-5339716;Reactome: R-HSA-198753;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-975957;Reactome: R-HSA-380284;Reactome: R-HSA-113501;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-1295596;Reactome: R-HSA-163685;Reactome: R-HSA-6804757;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-163767;Reactome: R-HSA-2995383;Reactome: R-HSA-202670;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-2465910;Reactome: R-HSA-5358752;Reactome: R-HSA-69231;Reactome: R-HSA-8854518;Reactome: R-HSA-5467348;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-5467340	"EML4 and NUDC in mitotic spindle formation";"DARPP-32 events";"Cyclin A/B1/B2 associated events during G2/M transition";"S37 mutants of beta-catenin aren't phosphorylated";"Regulation of PLK1 Activity at G2/M Transition";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Misspliced GSK3beta mutants stabilize beta-catenin";"ERK/MAPK targets";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Spry regulation of FGF signaling";"Integration of energy metabolism";"Regulation of TP53 Degradation";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"PP2A-mediated dephosphorylation of key metabolic factors";"Initiation of Nuclear Envelope Reformation";"ERKs are inactivated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"MASTL Facilitates Mitotic Progression";"T41 mutants of beta-catenin aren't phosphorylated";"Cyclin D associated events in G1";"AURKA Activation by TPX2";"Truncations of AMER1 destabilize the destruction complex";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AXIN missense mutants destabilize the destruction complex"
XP_049778097.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049780894.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049788272.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049784984.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049767398.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049768657.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980	"Ion channel transport";"Insulin receptor recycling";"Photosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis"
XP_049779514.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049765880.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049780967.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049769024.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049783924.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049784252.1	6	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_049787926.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049763734.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049763011.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049776569.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049780306.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049784834.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049776375.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049769748.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_049776959.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735	"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis"
XP_049776179.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049766500.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049776889.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-9603505;Reactome: R-HSA-113418;Reactome: R-HSA-167246	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"NTRK3 as a dependence receptor";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript"
XP_049774044.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis"
XP_049773411.1	5	Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors"
XP_049773997.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049766699.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049776373.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049781226.1	19	Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5172;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00660+6.2.1.5	"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"C5-Branched dibasic acid metabolism"
XP_049776241.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049765169.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049762458.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049787632.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049766778.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049784869.1	4	KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_049771094.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049783247.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_049780566.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049764011.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049785774.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668	"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049782717.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_049780793.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049780765.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_049788181.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049784571.1	7	Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381183	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_049774606.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049763397.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_049774955.1	3	Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269	"Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_049777809.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781082.1	5	MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis"
XP_049773211.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049770240.1	19	Reactome: R-HSA-114604;Reactome: R-HSA-5663220;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-428543	"GPVI-mediated activation cascade";"RHO GTPases Activate Formins";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"EGFR downregulation";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"Inactivation of CDC42 and RAC1"
XP_049787990.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049765890.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049763279.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049787952.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049762998.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_049785690.1	6	KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)"
XP_049778786.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049778379.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049781772.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049781687.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049784273.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation"
XP_049782248.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_049787219.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_049786689.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049776833.1	12	KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294;MetaCyc: PWY-5749;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7854;MetaCyc: PWY-5744	"Pyruvate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV";"Itaconate degradation";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation"
XP_049781617.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049776439.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049771597.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049771800.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049765401.1	14	KEGG: 00770+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5108;MetaCyc: PWY-5057;MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5076;MetaCyc: PWY-7767;MetaCyc: PWY-5101;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42	"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis V";"L-valine degradation II";"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism"
XP_049786009.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049785416.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_049777319.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049763745.1	33	Reactome: R-HSA-6781827;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-69202;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-75953	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"HIV Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation"
XP_049774916.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049778423.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049782402.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049774599.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_049763451.1	5	Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_049774888.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049774748.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049776887.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049763409.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049780841.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049763674.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049764093.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049782016.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049787936.1	12	MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5856	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_049767463.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_049763257.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049775067.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049777769.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049775291.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049770535.1	6	MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism"
XP_049778070.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775213.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6	"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_049766624.1	14	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852	"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Macroautophagy"
XP_049784873.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049774129.1	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
XP_049767372.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049780450.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049762611.1	56	Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091	"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells"
XP_049762945.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049780309.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049786822.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049784504.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_049773856.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049784039.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049762847.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049772282.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049774712.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049774739.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049778147.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"Purine metabolism";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_049777799.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049782721.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049765710.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049775690.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049787010.1	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation"
XP_049775999.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049780511.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_049788356.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_049785080.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049765047.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049782238.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049764804.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049773204.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049780449.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049782806.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049774737.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049782284.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_049764741.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Fanconi Anemia Pathway"
XP_049777589.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049780957.1	4	MetaCyc: PWY-5028;MetaCyc: PWY-5030;Reactome: R-HSA-70921;KEGG: 00340+4.3.1.3	"L-histidine degradation II";"L-histidine degradation III";"Histidine catabolism";"Histidine metabolism"
XP_049768495.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049762827.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049784576.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049771171.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049770243.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049767466.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation"
XP_049783991.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_049768644.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781893.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049783133.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859	"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly"
XP_049774135.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_049778377.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_049788332.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049777468.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_049787566.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049773989.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_049782724.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049771761.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049774503.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049776015.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049764688.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049764092.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin"
XP_049763018.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049765889.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation"
XP_049784737.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049770725.1	2	MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis"
XP_049768783.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049765231.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049771551.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_049766203.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049772954.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049784962.1	52	Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664	"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation"
XP_049777161.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-156581	"Ub-specific processing proteases";"Methylation"
XP_049775855.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049766460.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049773727.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_049767397.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling"
XP_049777598.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049777997.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049787841.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049775625.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049787462.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049769325.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049783912.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049764117.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706	"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling"
XP_049773205.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049767549.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049784143.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049774581.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_049785201.1	7	MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499	"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane"
XP_049763887.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049769930.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_049771489.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5872	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_049778350.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049775182.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_049765265.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049786960.1	9	KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18	"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450"
XP_049780440.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049776405.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049784660.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049775075.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_049776643.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049780819.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049777556.1	7	KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation"
XP_049768697.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049780988.1	5	Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049765769.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049762856.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049775319.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049769644.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-429947	"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_049777805.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049787770.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781705.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_049778007.1	2	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_049774910.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049775346.1	6	Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species"
XP_049768919.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695	"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Neutrophil degranulation"
XP_049765544.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049763699.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_049776047.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049767020.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049788269.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049773748.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049784935.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_049777911.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049774767.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049787619.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049774242.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049775922.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049784094.1	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_049776636.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049787993.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049774988.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049777414.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73863	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination"
XP_049770923.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049763380.1	10	Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264	"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_049787248.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049780990.1	5	Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049778602.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787035.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049771667.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049785332.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049763912.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_049778483.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049771604.1	10	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Ub-specific processing proteases";"Relaxin signaling pathway";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049781157.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049774418.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049781957.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049786721.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049785709.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049780258.1	7	MetaCyc: PWY-2941;MetaCyc: PWY-8088;KEGG: 00300+4.3.3.7;MetaCyc: PWY-5097;Reactome: R-HSA-389661;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2942	"L-lysine biosynthesis II";"Dipicolinate biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis VI";"Glyoxylate metabolism and glycine degradation";"Monobactam biosynthesis";"L-lysine biosynthesis III"
XP_049775466.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049781464.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049773991.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049769281.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049767122.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773759.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049767225.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783222.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049772413.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049778589.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049765206.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049780514.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049780365.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization"
XP_049780805.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049784318.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049771662.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049780418.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049777457.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049764166.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049766937.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049765590.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049780810.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049786510.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_049785707.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049781419.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049786508.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049782681.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049774791.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049766956.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_049765703.1	16	Reactome: R-HSA-5602680;Reactome: R-HSA-166058;Reactome: R-HSA-3134963;Reactome: R-HSA-1236974;Reactome: R-HSA-6811558;Reactome: R-HSA-5603041;Reactome: R-HSA-5603037;Reactome: R-HSA-5602498;Reactome: R-HSA-975155;Reactome: R-HSA-1257604;Reactome: R-HSA-975110;Reactome: R-HSA-1810476;Reactome: R-HSA-9020702;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-209543	"MyD88 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"ER-Phagosome pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"PIP3 activates AKT signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"RIP-mediated NFkB activation via ZBP1";"Interleukin-1 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"p75NTR recruits signalling complexes"
XP_049777358.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_049785734.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049765293.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049777711.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049779425.1	18	MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1	"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"(R)-cysteate degradation";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism"
XP_049780884.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049779926.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049780001.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049771129.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049765941.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049774705.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049775123.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Degradation of AXIN"
XP_049782043.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661	"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Folate polyglutamylation";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Metabolism of folate and pterines";"One carbon pool by folate";"Methane metabolism";"Glycine betaine degradation I"
XP_049765475.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049776083.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049777343.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_049765542.1	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis"
XP_049771797.1	6	KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17	"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation"
XP_049776884.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049771602.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049770615.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049766477.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049777280.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-983168;Reactome: R-HSA-977225	"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation"
XP_049772932.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049778053.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049765159.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049765862.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049786195.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_049775082.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_049768868.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049774029.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049765335.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049778532.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049768125.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049777510.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049766936.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049765987.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049762638.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_049780289.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049786111.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049776369.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049766906.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049787011.1	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;MetaCyc: PWY-7922	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049764168.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049762824.1	10	KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_049784301.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049765171.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049783491.1	5	MetaCyc: PWY-6614;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841	"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)"
XP_049772197.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049778592.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049762648.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049769816.1	12	Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-5250924	"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression"
XP_049774132.1	7	Reactome: R-HSA-171319;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-5696394	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER"
XP_049782899.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777364.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049765027.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism"
XP_049767198.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773609.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_049762790.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_049785770.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_049765835.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049762855.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049785787.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-174430	"DNA replication initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation"
XP_049763238.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_049777579.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049787032.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049771125.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049773538.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049767760.1	21	Reactome: R-HSA-933542;Reactome: R-HSA-5684264;Reactome: R-HSA-5603027;Reactome: R-HSA-937039;Reactome: R-HSA-1810476;Reactome: R-HSA-168927;Reactome: R-HSA-5602636;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-1236974;Reactome: R-HSA-5357905;Reactome: R-HSA-975144;Reactome: R-HSA-937041;Reactome: R-HSA-202424;Reactome: R-HSA-5603029;Reactome: R-HSA-933543	"TRAF6 mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"IRAK1 recruits IKK complex";"RIP-mediated NFkB activation via ZBP1";"TICAM1, RIP1-mediated IKK complex recruitment";"IKBKB deficiency causes SCID";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"ER-Phagosome pathway";"Regulation of TNFR1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IKK complex recruitment mediated by RIP1";"Downstream TCR signaling";"IkBA variant leads to EDA-ID";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10"
XP_049769687.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049768482.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049763631.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049771657.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049780755.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049775622.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049781614.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049784572.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_049783746.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049788081.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049783822.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049778724.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049775472.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049778696.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049772513.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049763682.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049766071.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049779213.1	3	Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049766855.1	14	MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis"
XP_049767473.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_049776824.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049768937.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049767374.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049772105.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5576890;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5576893;Reactome: R-HSA-6802952;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Phase 3 - rapid repolarisation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Phase 2 - plateau phase";"Signaling by BRAF and RAF fusions";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049783979.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049773233.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049765246.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049780160.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049769300.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049784578.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049779861.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049778986.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049786805.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis"
XP_049762997.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049773777.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049765487.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049776177.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049774670.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism"
XP_049774451.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049762237.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_049776204.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049763704.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_049773442.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049778550.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049779378.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049765655.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049775750.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049767230.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049780329.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049766529.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049777178.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049765379.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049773080.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_049774025.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049773860.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049763475.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049778984.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049785227.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783581.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049786767.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049786644.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049763976.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049764534.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049780322.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049778611.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18	"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049779074.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3371453	"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response"
XP_049787918.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049769070.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049774801.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_049763310.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049769081.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049782113.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049783983.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049763504.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780524.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049786588.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049780466.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_049774350.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049768737.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049786914.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049767923.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049773536.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049775252.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049778548.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049784617.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049775671.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049782377.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8866652	"Regulation of TNFR1 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_049766619.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049767671.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-5651801	"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049771845.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049781423.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_049785721.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049765749.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049772856.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_049776378.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695	"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation"
XP_049778508.1	5	Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397	"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049786275.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049770920.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism"
XP_049775393.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049778833.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049780965.1	19	Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8963901	"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"VLDL clearance";"VLDL assembly";"Chylomicron assembly";"Clathrin-mediated endocytosis";"LDL clearance";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling"
XP_049783541.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049784282.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_049767115.1	8	Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_049779613.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049776920.1	5	KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;Reactome: R-HSA-1368108	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049776181.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049766606.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049784024.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049785568.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049778364.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-400206;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock"
XP_049778397.1	7	Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049783997.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049780257.1	4	Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049767297.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049764156.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049785250.1	4	Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-176187	"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Activation of ATR in response to replication stress"
XP_049785587.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
XP_049773623.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049763242.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049779181.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049778421.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;Reactome: R-HSA-5083632	"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049778389.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-6799;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-6519;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;MetaCyc: PWY-5994	"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Pederin biosynthesis";"Mupirocin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)"
XP_049787388.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049782120.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049780504.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425	"Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049776687.1	20	MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241	"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import"
XP_049774580.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6728	"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle"
XP_049783816.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049764071.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049767606.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_049775102.1	1	Reactome: R-HSA-73943	"Reversal of alkylation damage by DNA dioxygenases"
XP_049783234.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049776892.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_049764072.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049775824.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049784647.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049783432.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049773206.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049779633.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049765944.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_049766780.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049767254.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049787078.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription"
XP_049777580.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049777697.1	6	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_049774706.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049783178.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049779012.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049768552.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049776811.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049768984.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II"
XP_049787403.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049784417.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049776537.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049764780.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle"
XP_049776823.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049787091.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049779985.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049784495.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049767285.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049776191.1	4	KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22	"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism"
XP_049778720.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_049783965.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_049763597.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_049778036.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049776175.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049777061.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049762775.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049770090.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049787652.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049783278.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049763150.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049779230.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049763888.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-912446	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination"
XP_049781267.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049780375.1	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049764807.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049785137.1	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-6703	"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis"
XP_049765122.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-432720	"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis"
XP_049767646.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049763661.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049788231.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049772270.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049782055.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling"
XP_049787340.1	21	MetaCyc: PWY-7227;MetaCyc: PWY-7219;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7176	"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis"
XP_049772985.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion"
XP_049770950.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049781678.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049783772.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants"
XP_049762707.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049770767.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049782981.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation"
XP_049763687.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049779122.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049769648.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"ISG15 antiviral mechanism";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049786273.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049765836.1	4	MetaCyc: PWY-7394;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849	"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin III"
XP_049787538.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049782246.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049778217.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049765068.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_049762999.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II"
XP_049785595.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049779612.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049764853.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049762276.1	3	KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691	"Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I"
XP_049784575.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049784903.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_049781708.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049781377.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13	"Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Tryptophan catabolism";"Cysteine and methionine metabolism"
XP_049765333.1	7	KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms"
XP_049788052.1	4	Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049768852.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049769634.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_049773389.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049782029.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049780895.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049763847.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049773627.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049770772.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_049772285.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049777022.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049775335.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049763136.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049774103.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049763473.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049783479.1	11	Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_049774881.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049771521.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049778386.1	31	MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5966-1;MetaCyc: PWY-5994;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;MetaCyc: PWY-5147;MetaCyc: PWYG-321;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-6799;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-6519;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;MetaCyc: PWY-6113	"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis"
XP_049773949.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049779087.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_049785173.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049781396.1	14	MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080	"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I"
XP_049778837.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049781675.1	13	KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Sphingolipid metabolism";"Other glycan degradation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Sialic acid metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_049787268.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780351.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049778772.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049785714.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049774911.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049763445.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049769639.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-9010553	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs"
XP_049766612.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_049774783.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049762645.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049777058.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785133.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049776237.1	66	Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-176407;Reactome: R-HSA-5689880;Reactome: R-HSA-176409;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-2559582;Reactome: R-HSA-1236974;Reactome: R-HSA-179409;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-176412;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-176408;Reactome: R-HSA-69481;Reactome: R-HSA-8853884;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-141430;Reactome: R-HSA-180534;Reactome: R-HSA-174048;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751	"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"Senescence-Associated Secretory Phenotype (SASP)";"ER-Phagosome pathway";"APC-Cdc20 mediated degradation of Nek2A";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Phosphorylation of the APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of APC/C activators between G1/S and early anaphase";"G2/M Checkpoints";"Transcriptional Regulation by VENTX";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Cyclin B";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity"
XP_049783243.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)"
XP_049787445.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_049779205.1	3	MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049787861.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049763622.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049785654.1	9	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-8853383;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23	"Glycosaminoglycan degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Sphingolipid metabolism";"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_049776421.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049775253.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049775442.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_049787572.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049782123.1	9	Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-9656255;Reactome: R-HSA-110330	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049764301.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_049780557.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049781974.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_049771957.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049783376.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049785083.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778351.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_049787708.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049767260.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049765706.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049763651.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_049773946.1	4	MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_049787311.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049787896.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049762566.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049787086.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049779376.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-381340	"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation"
XP_049780651.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049779828.1	9	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049772251.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049774904.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049788418.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_049787831.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049773164.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176409	"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_049785204.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_049782996.1	7	Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-983168	"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778084.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049776250.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049766475.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049774962.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246	"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049773876.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049783988.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049787362.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049777366.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049780268.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049782937.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_049774157.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_049766069.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049776493.1	6	KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"3-phosphoinositide degradation"
XP_049774445.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049766983.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774116.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6664	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis"
XP_049767554.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049782498.1	15	Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-9664565;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795;Reactome: R-HSA-9665247;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665233	"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab"
XP_049772245.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049765328.1	11	Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;Reactome: R-HSA-168138;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-5668599;Reactome: R-HSA-1632852	"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"3-phosphoinositide biosynthesis";"RHO GTPases Activate NADPH Oxidases";"Macroautophagy"
XP_049777794.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049764947.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049764120.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706	"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling"
XP_049774469.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049785482.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_049764781.1	22	MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-7726;MetaCyc: PWY-7592;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_049779616.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049775550.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049773519.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049764524.1	14	MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-7279;MetaCyc: PWY-3781	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)"
XP_049774671.1	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067	"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049784748.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-203754	"Protein ubiquitination";"NOSIP mediated eNOS trafficking"
XP_049781932.1	16	MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.4;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5749;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5	"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Itaconate degradation";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism"
XP_049765812.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049764118.1	6	Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001	"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade"
XP_049776116.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049782205.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_049776440.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049768894.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis"
XP_049763115.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049788196.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049773401.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774610.1	4	Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_049762319.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049764809.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049764767.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049768386.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_049783642.1	4	KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9	"Propanoate metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism"
XP_049769041.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049763820.1	17	Reactome: R-HSA-69601;Reactome: R-HSA-1433557;Reactome: R-HSA-75035;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Signaling by SCF-KIT";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049787287.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-209560	"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NF-kB is activated and signals survival"
XP_049772996.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049787102.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Neutrophil degranulation"
XP_049770688.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483	"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Gap junction assembly";"Kinesins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs"
XP_049763596.1	6	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism"
XP_049766060.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049774069.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049784773.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049776573.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_049767200.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049785601.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049779478.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049786582.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5628897	"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes"
XP_049779135.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049775336.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049773984.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049783952.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049776921.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108	"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049762954.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049782986.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049787527.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049784150.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049773207.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049773416.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049767844.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049783169.1	16	Reactome: R-HSA-1266695;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-912631;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391	"Interleukin-7 signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Rho GTPase cycle";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by SCF-KIT";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of signaling by CBL";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling"
XP_049769093.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection"
XP_049772462.1	13	Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325	"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_049764921.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049764920.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049773825.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3108214	"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins"
XP_049778843.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_049777532.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_049777335.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049778541.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049777524.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049776989.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148	"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049785632.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049763379.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398	"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway"
XP_049776110.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_049762996.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049787751.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049787250.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049778115.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049783061.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049780948.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049783894.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049777529.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049786657.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049780709.1	11	KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7400	"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)"
XP_049780655.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049775381.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049775829.1	18	Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167238	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049782206.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs"
XP_049763259.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505	"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049781930.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049779961.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049766744.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049784067.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049774736.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049775121.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049783849.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049766523.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049776521.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049770953.1	8	MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - cytochrome P450"
XP_049775666.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049776422.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049765778.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049775796.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049771739.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049764088.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN"
XP_049776377.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049767810.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049774511.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787562.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049783875.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049773987.1	3	Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90	"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049771092.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049781951.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_049772103.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_049784513.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049769231.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049774416.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049771936.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Neutrophil degranulation";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_049781058.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049764582.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049767812.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049779743.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_049774388.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049776963.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049775482.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049781400.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320	"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Anchoring fibril formation"
XP_049787893.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049784133.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by Hippo";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049785127.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049773827.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049777089.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_049775259.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049780015.1	7	MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485	"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Role of phospholipids in phagocytosis"
XP_049787033.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049774082.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_049763973.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049765576.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049773138.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049787095.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049787988.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049780914.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049782978.1	5	MetaCyc: PWY-5531;MetaCyc: PWY-7159;MetaCyc: PWY-7766;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049774732.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_049776907.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049787917.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049784041.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049774315.1	14	Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00670+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-1622;MetaCyc: PWY-2161;MetaCyc: PWY-181;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841	"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Glycine betaine degradation I";"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Folate polyglutamylation";"Photorespiration ";"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Folate transformations II (plants)"
XP_049785343.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049784529.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049766476.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049780316.1	11	Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway"
XP_049767995.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049772975.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049771618.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049765162.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783569.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049775124.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049763601.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_049762235.1	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_049771931.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_049780301.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049776341.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049783439.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049780657.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049781676.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4341670;KEGG: 00511+3.2.1.23;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23	"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Galactose metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Defective NEU1 causes sialidosis";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism"
XP_049774768.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049763532.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049763317.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049763751.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049763071.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049763364.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049786490.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049782814.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049774885.1	6	KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)"
XP_049781083.1	5	KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892	"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_049764280.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation"
XP_049778654.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_049783706.1	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-6798695	"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Glycogen degradation II";"Neutrophil degranulation"
XP_049764057.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049782807.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049767591.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049787402.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049781665.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism"
XP_049768590.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049774563.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049775546.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049776239.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049767344.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_049770813.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049788270.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049785200.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049762828.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049773143.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-182218	"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation"
XP_049775345.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049766490.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049787664.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049777796.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049778333.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049777995.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049767257.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049777063.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763503.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049767049.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049764645.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049766740.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049764822.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049777630.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049776040.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049766727.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049767801.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049766724.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049783972.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049763911.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049763102.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049764789.1	10	MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_049780814.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049784508.1	5	Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007	"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events"
XP_049776262.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_049768483.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049784127.1	7	Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"Transcriptional Regulation by E2F6";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_049784395.1	12	MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-7118	"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Methane metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol"
XP_049785602.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049782135.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"HIV Transcription Initiation"
XP_049779626.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_049782147.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049767012.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049777858.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049783506.1	18	KEGG: 00280+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403;MetaCyc: PWY-5046;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00260+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00310+1.8.1.4;KEGG: 00020+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;Reactome: R-HSA-6783984	"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Propanoate metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Glycine, serine and threonine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Glycine degradation"
XP_049786770.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049765838.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_049783438.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_049783729.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049768974.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049787312.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049784583.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049769797.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049776416.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_049772085.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049778639.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049785797.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785790.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69166	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate"
XP_049785773.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049783616.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_049786718.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049768277.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049766963.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049767223.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-71336;MetaCyc: PWY-8060;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4	"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway"
XP_049776240.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049770746.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049765960.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049766781.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049784805.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049776983.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049777637.1	13	KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101	"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation"
XP_049778463.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs"
XP_049779762.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049781644.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049780395.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049767337.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049782268.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049787979.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049766679.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_049776037.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049781771.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049763107.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049776085.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049764881.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049763143.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049779999.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049787200.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_049785106.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049786892.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049762605.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049765555.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049779850.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049781977.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972	"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)"
XP_049772180.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049773641.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_049773916.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Neutrophil degranulation";"COPII-mediated vesicle transport"
XP_049762201.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_049775134.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049785069.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049784379.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049780516.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049783683.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_049782134.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_049765945.1	4	MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040	"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis"
XP_049778888.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049786015.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049773836.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049785105.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049780385.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787719.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049783257.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049783235.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049778426.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049777625.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_049775607.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049788493.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049776897.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049781613.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049778123.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049783844.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785090.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049767068.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049780299.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049774957.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049786106.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049767112.1	25	Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049778355.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049775988.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049778339.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049777557.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism"
XP_049778995.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_049770404.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049767086.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049784806.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049774806.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049772038.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049778932.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780387.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049785424.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049781594.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049778357.1	13	KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049786545.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049784315.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049785193.1	9	KEGG: 00550+2.4.1.227;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6385;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-6471;Reactome: R-HSA-5633231;KEGG: 00513+2.4.1.141;MetaCyc: PWY-5265	"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)"
XP_049774453.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049786774.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049784985.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049774240.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-212436	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway"
XP_049763276.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049763062.1	182	Reactome: R-HSA-1295596;Reactome: R-HSA-5668541;Reactome: R-HSA-9033241;Reactome: R-HSA-8852276;Reactome: R-HSA-6783310;Reactome: R-HSA-9020702;Reactome: R-HSA-5656121;Reactome: R-HSA-382556;Reactome: R-HSA-6804756;Reactome: R-HSA-5610780;Reactome: R-HSA-937072;Reactome: R-HSA-72764;Reactome: R-HSA-5654727;Reactome: R-HSA-72689;Reactome: R-HSA-6781827;Reactome: R-HSA-9013973;Reactome: R-HSA-1358803;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-2122947;Reactome: R-HSA-8866652;Reactome: R-HSA-5655862;Reactome: R-HSA-5654726;Reactome: R-HSA-69541;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8866654;Reactome: R-HSA-69231;Reactome: R-HSA-174048;Reactome: R-HSA-5654732;Reactome: R-HSA-975163;Reactome: R-HSA-69601;Reactome: R-HSA-8856828;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-5693565;Reactome: R-HSA-2122948;Reactome: R-HSA-156827;Reactome: R-HSA-2644606;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-937041;Reactome: R-HSA-4641263;Reactome: R-HSA-983168;Reactome: R-HSA-2173791;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8876493;Reactome: R-HSA-9646399;Reactome: R-HSA-8854050;Reactome: R-HSA-3134975;Reactome: R-HSA-936440;Reactome: R-HSA-5696397;Reactome: R-HSA-2559580;Reactome: R-HSA-5656169;Reactome: R-HSA-450321;Reactome: R-HSA-5696395;Reactome: R-HSA-6804760;Reactome: R-HSA-917729;Reactome: R-HSA-2408557;Reactome: R-HSA-1253288;Reactome: R-HSA-174184;Reactome: R-HSA-9013507;Reactome: R-HSA-917937;Reactome: R-HSA-156902;Reactome: R-HSA-2691232;Reactome: R-HSA-936964;Reactome: R-HSA-5675221;Reactome: R-HSA-1236974;Reactome: R-HSA-6807004;Reactome: R-HSA-532668;Reactome: R-HSA-2559582;Reactome: R-HSA-2894862;Reactome: R-HSA-5685942;Reactome: R-HSA-5689901;Reactome: R-HSA-205043;Reactome: R-HSA-1799339;Reactome: R-HSA-6804757;Reactome: R-HSA-9613829;Reactome: R-HSA-8863795;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-975110;Reactome: R-HSA-8939236;Reactome: R-HSA-3769402;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-201681;Reactome: R-HSA-901032;Reactome: R-HSA-9014325;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-8849469;Reactome: R-HSA-4641258;Reactome: R-HSA-209560;Reactome: R-HSA-5689896;Reactome: R-HSA-9010553;Reactome: R-HSA-6782135;Reactome: R-HSA-5654733;Reactome: R-HSA-1234176;Reactome: R-HSA-3322077;Reactome: R-HSA-5696400;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2565942;Reactome: R-HSA-192823;Reactome: R-HSA-2979096;Reactome: R-HSA-110314;Reactome: R-HSA-69481;Reactome: R-HSA-5689877;Reactome: R-HSA-168927;Reactome: R-HSA-937039;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-8951664;Reactome: R-HSA-2559585;Reactome: R-HSA-8948751;Reactome: R-HSA-168638;Reactome: R-HSA-6791226;Reactome: R-HSA-450302;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-1236382;Reactome: R-HSA-9633012;Reactome: R-HSA-174490;Reactome: R-HSA-5696394;Reactome: R-HSA-975957;Reactome: R-HSA-2173796;Reactome: R-HSA-5607761;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-6781823;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-2173795;Reactome: R-HSA-182971;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5675482;Reactome: R-HSA-2672351;Reactome: R-HSA-400253;Reactome: R-HSA-110312;Reactome: R-HSA-9645460;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-975956;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-175474;Reactome: R-HSA-174084;Reactome: R-HSA-8948747;Reactome: R-HSA-9615710;Reactome: R-HSA-110320;Reactome: R-HSA-162588;Reactome: R-HSA-209543;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-179409;Reactome: R-HSA-912631;Reactome: R-HSA-9637628;Reactome: R-HSA-168928;Reactome: R-HSA-68949;Reactome: R-HSA-8875360;Reactome: R-HSA-3785653;Reactome: R-HSA-5205685;Reactome: R-HSA-72695	"Spry regulation of FGF signaling";"TNFR2 non-canonical NF-kB pathway";"Peroxisomal protein import";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Fanconi Anemia Pathway";"Interleukin-1 signaling";"Translesion synthesis by POLI";"ABC-family proteins mediated transport";"Regulation of TP53 Activity through Phosphorylation";"Degradation of GLI1 by the proteasome";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Eukaryotic Translation Termination";"Negative regulation of FGFR2 signaling";"Formation of a pool of free 40S subunits";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of ERBB2:ERBB3 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"NOTCH1 Intracellular Domain Regulates Transcription";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Translesion synthesis by POLK";"Negative regulation of FGFR1 signaling";"Stabilization of p53";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Cyclin D associated events in G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Negative regulation of FGFR3 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Clathrin-mediated endocytosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated NOTCH1 Transmits Signal to the Nucleus";"L13a-mediated translational silencing of Ceruloplasmin expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"IKK complex recruitment mediated by RIP1";"Regulation of FZD by ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"InlA-mediated entry of Listeria monocytogenes into host cells";"Aggrephagy";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of innate immune responses to cytosolic DNA";"Negative regulators of DDX58/IFIH1 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Oxidative Stress Induced Senescence";"Termination of translesion DNA synthesis";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Methylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Selenocysteine synthesis";"Downregulation of ERBB4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Iron uptake and transport";"Peptide chain elongation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulation of MAPK pathway";"ER-Phagosome pathway";"Negative regulation of MET activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Senescence-Associated Secretory Phenotype (SASP)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDR through Homologous Recombination (HRR)";"Metalloprotease DUBs";"NRIF signals cell death from the nucleus";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of TP53 Degradation";"Chaperone Mediated Autophagy";"Downregulation of ERBB2 signaling";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deactivation of the beta-catenin transactivating complex";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"TCF dependent signaling in response to WNT";"ER Quality Control Compartment (ERQC)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Degradation of DVL";"NF-kB is activated and signals survival";"Ovarian tumor domain proteases";"Regulation of expression of SLITs and ROBOs";"Dual incision in TC-NER";"Negative regulation of FGFR4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Glycogen synthesis";"Dual Incision in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of PLK1 Activity at G2/M Transition";"Viral mRNA Translation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M Checkpoints";"Josephin domain DUBs";"TICAM1, RIP1-mediated IKK complex recruitment";"IRAK1 recruits IKK complex";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Neddylation";"Oncogene Induced Senescence";"Regulation of PTEN stability and activity";"NOD1/2 Signaling Pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"activated TAK1 mediates p38 MAPK activation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Membrane binding and targetting of GAG proteins";"DNA Damage Recognition in GG-NER";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Formation of TC-NER Pre-Incision Complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"EGFR downregulation";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of necroptotic cell death";"Stimuli-sensing channels";"Circadian Clock";"Translesion synthesis by REV1";"Alpha-protein kinase 1 signaling pathway";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Assembly Of The HIV Virion";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN localization";"Late endosomal microautophagy";"Translesion Synthesis by POLH";"Budding and maturation of HIV virion";"p75NTR recruits signalling complexes";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of signaling by CBL";"Modulation by Mtb of host immune system";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Orc1 removal from chromatin";"InlB-mediated entry of Listeria monocytogenes into host cell";"Myoclonic epilepsy of Lafora";"Pink/Parkin Mediated Mitophagy";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049787353.1	13	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-416482	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"EPHA-mediated growth cone collapse";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"G alpha (12/13) signalling events"
XP_049785076.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049784062.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757	"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation"
XP_049765168.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049783756.1	4	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism"
XP_049783922.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049763692.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6798695;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Neutrophil degranulation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049779540.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049767623.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049780823.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049784547.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049780661.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049778734.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049781063.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049777484.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049762885.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049763815.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049778641.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049763736.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777419.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049781642.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049774072.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049775439.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049782354.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049770804.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049786571.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049766929.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049769213.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049768554.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049764876.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049772224.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049774828.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049765887.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049785802.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777045.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_049785579.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_049787540.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049773758.1	17	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049786412.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049783065.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049773146.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5635838	"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"Activation of SMO"
XP_049777242.1	2	KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_049768384.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049766673.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049773941.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Neutrophil degranulation";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_049785353.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_049787769.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787709.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_049782211.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049773506.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-975634	"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport"
XP_049768081.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049783484.1	24	Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-163359;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-418597	"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events"
XP_049779336.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049783352.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049778507.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049762708.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049783141.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168	"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Neddylation";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049786813.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049769205.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049767315.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049783104.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049769406.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049786459.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049780499.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049762964.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049775092.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049777838.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775628.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049787853.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049769365.1	3	Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807	"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling"
XP_049764288.1	10	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_049775759.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049767064.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049772878.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049766017.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_049781758.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049773753.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049766904.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049763434.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049777396.1	3	Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709	"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins"
XP_049766068.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049787141.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049783385.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_049784499.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049781997.1	5	Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853	"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)"
XP_049766623.1	14	Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"HCMV Early Events";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
XP_049781061.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049781040.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049784507.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049767706.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049776182.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049772951.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049775733.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049771162.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049786947.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049773846.1	20	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of TP53 Degradation";"Macroautophagy";"mTOR signaling pathway";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049787650.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049774922.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049784139.1	15	Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795;Reactome: R-HSA-9665247;Reactome: R-HSA-9665244;Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810	"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII"
XP_049765654.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049784030.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049788206.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049786472.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_049784589.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049770313.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049769638.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-9010553	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs"
XP_049768262.1	40	Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-75955	"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"HIV Transcription Initiation";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation"
XP_049766840.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049779646.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049777889.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II"
XP_049767863.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049770882.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049767160.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049769814.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408	"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation"
XP_049768103.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7411	"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_049769286.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049774793.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049783644.1	4	KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247	"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids"
XP_049786002.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049773821.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049775181.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_049784645.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate"
XP_049775960.1	4	KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_049767774.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049764003.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049786690.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049770877.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049786226.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049766762.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049785062.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049785324.1	8	KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis"
XP_049780871.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_049771941.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237	"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2"
XP_049787717.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049763093.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049763366.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_049776830.1	12	KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7854;MetaCyc: PWY-5744;MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-6728;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Methylaspartate cycle";"Pyruvate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV"
XP_049775295.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_049782630.1	19	Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-202733	"LDL remodeling";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"VLDL assembly";"VLDL clearance";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Chylomicron assembly";"LDL clearance";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Chylomicron clearance";"Cell surface interactions at the vascular wall"
XP_049779967.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049773136.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049780917.1	10	KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"RSK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection"
XP_049767465.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049787322.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049777888.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_049785708.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049774506.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049764810.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049778961.1	12	Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;MetaCyc: PWY-6121;MetaCyc: PWY-6277	"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_049786166.1	13	KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-2261;MetaCyc: PWY-6842;MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112	"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification"
XP_049780682.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049773106.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049777802.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049784418.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049765805.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049787919.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049778760.1	3	Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_049786578.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049778420.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632	"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049787288.1	5	Reactome: R-HSA-9020702;Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209543	"Interleukin-1 signaling";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes"
XP_049781993.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049767804.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049764299.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049767080.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049763421.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049765924.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049776499.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049773730.1	10	Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_049785859.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049766396.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049781478.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368108	"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049773130.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049767103.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049767132.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049776872.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049787233.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049782666.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049785147.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049770621.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049765028.1	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation";"Glycerolipid metabolism"
XP_049767522.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_049786590.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8948700	"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_049763547.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049776068.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049786733.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049773078.1	57	Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870	"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins"
XP_049762632.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049775889.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049776881.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_049767214.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049780674.1	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969	"Glycerolipid metabolism";"Synthesis of PC";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PE";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina"
XP_049785689.1	6	MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-2426168	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)"
XP_049779008.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049781618.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049775078.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_049766087.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049776424.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049776844.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049764912.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049770492.1	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"DNA methylation"
XP_049767273.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049780627.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049774788.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049766528.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049768917.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756	"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation"
XP_049787806.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049781611.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049784808.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049781490.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_049767546.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049785185.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049770895.1	15	MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6901	"Rubisco shunt";"Purine metabolism";"Glycolysis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation"
XP_049775176.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049781398.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049787337.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049775748.1	25	Reactome: R-HSA-8951936;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-8934593;Reactome: R-HSA-8931987;Reactome: R-HSA-8939245;Reactome: R-HSA-8877330;Reactome: R-HSA-8940973;Reactome: R-HSA-8936459;Reactome: R-HSA-8939246;Reactome: R-HSA-8939902;Reactome: R-HSA-8941333;Reactome: R-HSA-8941332;Reactome: R-HSA-9018519;Reactome: R-HSA-8935964;Reactome: R-HSA-8941326;Reactome: R-HSA-8941284;Reactome: R-HSA-9616222;Reactome: R-HSA-8878166;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8939256;Reactome: R-HSA-8951911;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247	"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX2 expression and activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration";"Estrogen-dependent gene expression";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates bone development";"RUNX2 regulates chondrocyte maturation";"Transcriptional regulation of granulopoiesis";"Transcriptional regulation by RUNX2";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling"
XP_049768410.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049765139.1	4	MetaCyc: PWY-6832;KEGG: 00440+2.6.1.37;Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"2-aminoethylphosphonate degradation II";"Phosphonate and phosphinate metabolism";"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049770766.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049786575.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049765691.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049763729.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport"
XP_049786379.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049786253.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049776882.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-375276	"G alpha (s) signalling events";"Peptide ligand-binding receptors"
XP_049785022.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049784947.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049783273.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049779968.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049787920.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049766782.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049787271.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049788211.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049784241.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049779923.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049786800.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049773170.1	5	MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;MetaCyc: PWY-5269	"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II"
XP_049778982.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049776800.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049763785.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049770364.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049772213.1	15	MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Purine metabolism";"Rubisco shunt"
XP_049773841.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049776931.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049764237.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049763294.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049763443.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049780127.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_049767125.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049784544.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049786177.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-6842;MetaCyc: PWY-7533;MetaCyc: PWY-4061	"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I"
XP_049763009.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049772255.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049763168.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_049780943.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781037.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049778118.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049783742.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_049787253.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049766682.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049784767.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049770842.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049782949.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049763469.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049787854.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049773834.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049767811.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049775392.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049774280.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049776686.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_049781690.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775043.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049768310.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_049762787.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049778132.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049762484.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049768249.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049769230.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049774061.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049772290.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049765699.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049778712.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049772240.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion"
XP_049786754.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167287	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery"
XP_049787460.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049780578.1	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049787222.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049762452.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049767673.1	6	Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-73933	"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)"
XP_049781604.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049777854.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049765329.1	11	MetaCyc: PWY-6352;Reactome: R-HSA-5668599;Reactome: R-HSA-1632852;Reactome: R-HSA-1660499;Reactome: R-HSA-168138;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517	"3-phosphoinositide biosynthesis";"RHO GTPases Activate NADPH Oxidases";"Macroautophagy";"Synthesis of PIPs at the plasma membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane"
XP_049783425.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049777377.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766734.1	7	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Glutathione metabolism"
XP_049770847.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion"
XP_049777792.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049765128.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049775221.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049767042.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049775367.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897	"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes"
XP_049774872.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_049776879.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_049774969.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049782380.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049773166.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176407	"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049776910.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049785326.1	8	KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1	"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049782410.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049763686.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_049766952.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049778547.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049768735.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049784648.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049764058.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049787427.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049767088.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049770363.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049787651.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049778503.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049786502.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion"
XP_049785948.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_049781435.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049782352.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049770386.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049780266.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049781955.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049787149.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049774905.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_049783218.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_049788403.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_049768568.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049768165.1	12	KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683	"Sulfur metabolism";"Monobactam biosynthesis";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfite oxidation III";"Selenocompound metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III"
XP_049762226.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049783954.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-6803207	"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049766675.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049781321.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049762786.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049780989.1	5	Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049785503.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049778485.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049765016.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Neutrophil degranulation";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_049773639.1	7	KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione metabolism";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_049788339.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773110.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_049783357.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049778834.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049786520.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049766953.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049776988.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148	"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049775548.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049788182.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049788145.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049780177.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049774884.1	6	KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)"
XP_049776358.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049786801.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049763844.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049780271.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049768232.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-9609690	"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events"
XP_049778067.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049767121.1	1	Reactome: R-HSA-156588	"Glucuronidation"
YP_010401625.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049765679.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_049778079.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049784267.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049778546.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049783277.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049778743.1	29	Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049769280.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049774992.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049780486.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049766082.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049788043.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049769200.1	9	KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;Reactome: R-HSA-3371599	"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_049777537.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501	"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049771482.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049782014.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049770829.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049766791.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049776820.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery"
XP_049785058.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049774924.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049771249.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049774667.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate"
XP_049775787.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049776644.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049776930.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049776758.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_049781668.1	11	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049775368.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049783192.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51	"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_049779979.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049776188.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049763691.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_049787188.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049785697.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049775689.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049783558.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049781355.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049781091.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049777021.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049781788.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049770821.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049777652.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049772386.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049762792.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049781854.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049788053.1	4	Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049776779.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049785931.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049772254.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049785071.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049782785.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049777721.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049775079.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_049783505.1	18	KEGG: 00620+1.8.1.4;KEGG: 00010+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-71403;Reactome: R-HSA-70895;KEGG: 00380+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-5362517;MetaCyc: PWY-5084;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00310+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00260+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00640+1.8.1.4	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citric acid cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Glycine degradation";"Signaling by Retinoic Acid";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Lysine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine, serine and threonine metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Propanoate metabolism"
XP_049767287.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_049779493.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_049787563.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049782637.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049767069.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049780591.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-9620244	"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Long-term potentiation"
XP_049762513.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_049785599.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766774.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049766349.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778125.1	10	KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7411	"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_049764945.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049780586.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066	"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049787585.1	20	MetaCyc: PWY-7227;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7205;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;Reactome: R-HSA-380320;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222	"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_049777790.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049786437.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_049772368.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_049782975.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism"
XP_049785701.1	8	KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336	"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049765349.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049769976.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049785456.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049781475.1	11	Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-3214858	"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RMTs methylate histone arginines"
XP_049780758.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049787762.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049782288.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049780726.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049784047.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049779450.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049774470.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049770156.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049767196.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049768539.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049780463.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049783366.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113	"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049774526.1	3	MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049776477.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049764345.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049787415.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049766278.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049784717.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049765506.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_049766022.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_049774392.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049775313.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049784596.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049778133.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049762599.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049775044.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049767457.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049770426.1	8	Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-8941284;Reactome: R-HSA-373080;Reactome: R-HSA-5658034	"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Activation of SMO";"RUNX2 regulates chondrocyte maturation";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np"
XP_049780683.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049770805.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049771557.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_049767787.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049762321.1	13	KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II"
XP_049768153.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049767271.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049780500.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049769420.1	14	MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00630+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-181;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;MetaCyc: PWY-1622;MetaCyc: PWY-5497;KEGG: 00260+2.1.2.1	"Glycine betaine degradation I";"Methane metabolism";"One carbon pool by folate";"Glyoxylate and dicarboxylate metabolism";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Folate polyglutamylation";"Photorespiration ";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Glycine, serine and threonine metabolism"
XP_049783458.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049768293.1	10	MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis"
XP_049782942.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049780764.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_049785757.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-3928665	"Nef Mediated CD4 Down-regulation";"LDL clearance";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells"
XP_049780564.1	10	MetaCyc: PWY-6839;MetaCyc: PWY-7419;MetaCyc: PWY-7769;MetaCyc: PWY-6322;MetaCyc: PWY-7510;MetaCyc: PWY-5757;KEGG: 00440+5.4.2.9;KEGG: 00998+5.4.2.9;MetaCyc: PWY-6682;MetaCyc: PWY-8067	"2-aminoethylphosphonate biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Phosalacine biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Rhizocticin A and B biosynthesis";"Fosfomycin biosynthesis";"Phosphonate and phosphinate metabolism";"Biosynthesis of various secondary metabolites - part 2";"Dehydrophos biosynthesis";"Methylphosphonate biosynthesis"
XP_049762647.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049787184.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787521.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends"
XP_049783568.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049767653.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049781350.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049769728.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049775230.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049786671.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049768481.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049784457.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049779406.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049787980.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049767862.1	16	Reactome: R-HSA-1227986;Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1251985;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1250342;Reactome: R-HSA-5673001	"Signaling by ERBB2";"GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Nuclear signaling by ERBB4";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB4 signaling";"RAF/MAP kinase cascade"
XP_049777699.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049785801.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049782845.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
XP_049769155.1	29	Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Meiotic recombination";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation"
XP_049763772.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport"
XP_049783427.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049784085.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049786173.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049785884.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049773134.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049770353.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049772257.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049784721.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049777884.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049775135.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049770673.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_049770400.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049763652.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049787363.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049773214.1	4	MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_049776992.1	10	MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism"
XP_049778382.1	6	Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049764868.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049777470.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_049776890.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049779283.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049766538.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049780873.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049774302.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049766809.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049767018.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049762779.1	1	Reactome: R-HSA-1234176	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049770840.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis of PC"
XP_049783852.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695	"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation"
XP_049785037.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049762678.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049786894.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049779933.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049767460.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation"
XP_049764860.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049775968.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049774081.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049774915.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049778387.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049766907.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049774948.1	9	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049778810.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049782228.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_049777286.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049767622.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049782163.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_049787781.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049782812.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049780579.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066	"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049763568.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049783542.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049781356.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049778391.1	31	MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;Reactome: R-HSA-163765;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-6799;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-7746;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-8012;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-5989	"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Pederin biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)"
XP_049762576.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_049778580.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_049784125.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_049783771.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049767124.1	10	KEGG: 00190+3.6.1.1;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7805;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-7807;Reactome: R-HSA-9640463;Reactome: R-HSA-71737;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Oxidative phosphorylation";"Cutin, suberine and wax biosynthesis";"(aminomethyl)phosphonate degradation";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Glyphosate degradation III";"Wax biosynthesis";"Pyrophosphate hydrolysis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_049766945.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049782175.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_049780581.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692	"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Regulation of MECP2 expression and activity"
XP_049786825.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049764728.1	3	KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_049775745.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778113.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408	"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism"
XP_049778797.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049781337.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049775606.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049777887.1	9	KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52	"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series"
XP_049775917.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_049780456.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_049782989.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049787180.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049782969.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049762850.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049780677.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049766723.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847	"UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones"
XP_049787254.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_049781999.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_049775963.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049767523.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_049769631.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049766441.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049787825.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049787925.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049775987.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_049785476.1	11	MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675	"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)"
XP_049787805.1	33	Reactome: R-HSA-73762;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167172	"RNA Polymerase I Transcription Initiation";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome"
XP_049780083.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049777328.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049771505.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049777065.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049768152.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049769674.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049766915.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049777895.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism"
XP_049785282.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-532668;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050	"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_049788007.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_049784438.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049777359.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049762233.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049762636.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049779024.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049784492.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049763295.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049763697.1	179	Reactome: R-HSA-450302;Reactome: R-HSA-6791226;Reactome: R-HSA-168638;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-937039;Reactome: R-HSA-5689877;Reactome: R-HSA-168927;Reactome: R-HSA-69481;Reactome: R-HSA-110314;Reactome: R-HSA-2979096;Reactome: R-HSA-192823;Reactome: R-HSA-2559585;Reactome: R-HSA-8951664;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5654733;Reactome: R-HSA-9010553;Reactome: R-HSA-6782135;Reactome: R-HSA-5689896;Reactome: R-HSA-209560;Reactome: R-HSA-4641258;Reactome: R-HSA-8849469;Reactome: R-HSA-180585;Reactome: R-HSA-2565942;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5696400;Reactome: R-HSA-3322077;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-975110;Reactome: R-HSA-8863795;Reactome: R-HSA-9613829;Reactome: R-HSA-6804757;Reactome: R-HSA-174178;Reactome: R-HSA-9014325;Reactome: R-HSA-201681;Reactome: R-HSA-901032;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-3769402;Reactome: R-HSA-8939236;Reactome: R-HSA-179409;Reactome: R-HSA-912631;Reactome: R-HSA-168928;Reactome: R-HSA-9637628;Reactome: R-HSA-5357905;Reactome: R-HSA-975144;Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-5205685;Reactome: R-HSA-3785653;Reactome: R-HSA-8875360;Reactome: R-HSA-68949;Reactome: R-HSA-175474;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-975956;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-209543;Reactome: R-HSA-110320;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-8948747;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-2173795;Reactome: R-HSA-182971;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-6781823;Reactome: R-HSA-5607761;Reactome: R-HSA-1169408;Reactome: R-HSA-9645460;Reactome: R-HSA-2672351;Reactome: R-HSA-110312;Reactome: R-HSA-400253;Reactome: R-HSA-5675482;Reactome: R-HSA-202424;Reactome: R-HSA-9633012;Reactome: R-HSA-174490;Reactome: R-HSA-1236382;Reactome: R-HSA-5689880;Reactome: R-HSA-2173796;Reactome: R-HSA-975957;Reactome: R-HSA-5696394;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-8856828;Reactome: R-HSA-69601;Reactome: R-HSA-975163;Reactome: R-HSA-174048;Reactome: R-HSA-5654732;Reactome: R-HSA-5655862;Reactome: R-HSA-8866652;Reactome: R-HSA-2122947;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-8866654;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-69541;Reactome: R-HSA-2173788;Reactome: R-HSA-5654726;Reactome: R-HSA-72764;Reactome: R-HSA-937072;Reactome: R-HSA-5610780;Reactome: R-HSA-6804756;Reactome: R-HSA-9013973;Reactome: R-HSA-1358803;Reactome: R-HSA-72706;Reactome: R-HSA-6781827;Reactome: R-HSA-72689;Reactome: R-HSA-5654727;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-9033241;Reactome: R-HSA-1295596;Reactome: R-HSA-5656121;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-6783310;Reactome: R-HSA-5675221;Reactome: R-HSA-936964;Reactome: R-HSA-1236974;Reactome: R-HSA-2691232;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-205043;Reactome: R-HSA-5689901;Reactome: R-HSA-5685942;Reactome: R-HSA-532668;Reactome: R-HSA-2894862;Reactome: R-HSA-2559582;Reactome: R-HSA-6807004;Reactome: R-HSA-5696395;Reactome: R-HSA-450321;Reactome: R-HSA-5656169;Reactome: R-HSA-2559580;Reactome: R-HSA-936440;Reactome: R-HSA-5696397;Reactome: R-HSA-3134975;Reactome: R-HSA-917937;Reactome: R-HSA-9013507;Reactome: R-HSA-174184;Reactome: R-HSA-2408557;Reactome: R-HSA-1253288;Reactome: R-HSA-6804760;Reactome: R-HSA-917729;Reactome: R-HSA-937041;Reactome: R-HSA-8854050;Reactome: R-HSA-8876493;Reactome: R-HSA-9646399;Reactome: R-HSA-2173791;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641263;Reactome: R-HSA-2644606;Reactome: R-HSA-156827;Reactome: R-HSA-2122948;Reactome: R-HSA-5693565;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-977225;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607	"activated TAK1 mediates p38 MAPK activation";"Major pathway of rRNA processing in the nucleolus and cytosol";"NOD1/2 Signaling Pathway";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"IRAK1 recruits IKK complex";"Josephin domain DUBs";"TICAM1, RIP1-mediated IKK complex recruitment";"G2/M Checkpoints";"Recognition of DNA damage by PCNA-containing replication complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Viral mRNA Translation";"Oncogene Induced Senescence";"Neddylation";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Negative regulation of FGFR4 signaling";"Regulation of expression of SLITs and ROBOs";"Dual incision in TC-NER";"Ovarian tumor domain proteases";"NF-kB is activated and signals survival";"Degradation of DVL";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Vif-mediated degradation of APOBEC3G";"Regulation of PLK1 Activity at G2/M Transition";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dual Incision in GG-NER";"Glycogen synthesis";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Downregulation of ERBB2 signaling";"Chaperone Mediated Autophagy";"Regulation of TP53 Degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TCF dependent signaling in response to WNT";"ER Quality Control Compartment (ERQC)";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of signaling by CBL";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Modulation by Mtb of host immune system";"Regulation of TNFR1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Pink/Parkin Mediated Mitophagy";"Myoclonic epilepsy of Lafora";"InlB-mediated entry of Listeria monocytogenes into host cell";"Orc1 removal from chromatin";"Assembly Of The HIV Virion";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"p75NTR recruits signalling complexes";"Translesion Synthesis by POLH";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Regulation of PTEN localization";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"EGFR downregulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Formation of TC-NER Pre-Incision Complex";"Dectin-1 mediated noncanonical NF-kB signaling";"ISG15 antiviral mechanism";"Alpha-protein kinase 1 signaling pathway";"Stimuli-sensing channels";"Translesion synthesis by REV1";"Circadian Clock";"Regulation of necroptotic cell death";"Downstream TCR signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Membrane binding and targetting of GAG proteins";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Ub-specific processing proteases";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"DNA Damage Recognition in GG-NER";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Clathrin-mediated endocytosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Negative regulation of FGFR3 signaling";"Translesion synthesis by POLK";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"NOTCH1 Intracellular Domain Regulates Transcription";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"E3 ubiquitin ligases ubiquitinate target proteins";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Stabilization of p53";"Downregulation of TGF-beta receptor signaling";"Negative regulation of FGFR1 signaling";"Eukaryotic Translation Termination";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Degradation of GLI1 by the proteasome";"Regulation of TP53 Activity through Phosphorylation";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of ERBB2:ERBB3 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of a pool of free 40S subunits";"Negative regulation of FGFR2 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Peroxisomal protein import";"Spry regulation of FGF signaling";"Translesion synthesis by POLI";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Fanconi Anemia Pathway";"Negative regulation of MAPK pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"ER-Phagosome pathway";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"NRIF signals cell death from the nucleus";"Metalloprotease DUBs";"HDR through Homologous Recombination (HRR)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of MET activity";"Formation of Incision Complex in GG-NER";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Termination of translesion DNA synthesis";"Oxidative Stress Induced Senescence";"Negative regulators of DDX58/IFIH1 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of innate immune responses to cytosolic DNA";"Iron uptake and transport";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Selenocysteine synthesis";"Downregulation of ERBB4 signaling";"Regulation of TP53 Activity through Methylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"IKK complex recruitment mediated by RIP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"InlA-mediated entry of Listeria monocytogenes into host cells";"Aggrephagy";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of FZD by ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activated NOTCH1 Transmits Signal to the Nucleus";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Amyloid fiber formation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends"
XP_049770547.1	7	KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;MetaCyc: PWY-7980	"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"ATP biosynthesis"
XP_049780118.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049772256.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049787194.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism"
XP_049766777.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049763101.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049777546.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-174430	"DNA replication initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation"
XP_049784287.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-418555	"G-protein activation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events"
XP_049787568.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049785458.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049768710.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049766878.1	14	Reactome: R-HSA-1474228;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-6798695;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Degradation of the extracellular matrix";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Neutrophil degranulation";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049764704.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049776542.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049782174.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049773830.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049783077.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049768918.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853	"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Synthesis of PC";"Condensation of Prometaphase Chromosomes"
XP_049781555.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049786713.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049783153.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049769299.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778501.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049785177.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049774751.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049768738.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049778335.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049763131.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049781666.1	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004	"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I"
XP_049788482.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783999.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049783840.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049763494.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049769474.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"Purine metabolism"
XP_049785356.1	7	KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_049777066.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049762602.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049767808.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049784776.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049769137.1	5	Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049782987.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049767764.1	21	Reactome: R-HSA-202424;Reactome: R-HSA-5603029;Reactome: R-HSA-933543;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-975144;Reactome: R-HSA-937041;Reactome: R-HSA-1236974;Reactome: R-HSA-5357905;Reactome: R-HSA-5602636;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-933542;Reactome: R-HSA-5684264;Reactome: R-HSA-5603027;Reactome: R-HSA-1810476;Reactome: R-HSA-937039;Reactome: R-HSA-168927	"Downstream TCR signaling";"IkBA variant leads to EDA-ID";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IKK complex recruitment mediated by RIP1";"ER-Phagosome pathway";"Regulation of TNFR1 signaling";"IKBKB deficiency causes SCID";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"TRAF6 mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"RIP-mediated NFkB activation via ZBP1";"IRAK1 recruits IKK complex";"TICAM1, RIP1-mediated IKK complex recruitment"
XP_049786023.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049780795.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049763092.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049763083.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049762436.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049778124.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049771738.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049778730.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049770392.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
XP_049774080.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049778489.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040	"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis"
XP_049769284.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049787597.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049765183.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049784215.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049787341.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049772910.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_049767105.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049770244.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049773213.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049778134.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055	"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_049783279.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049782836.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049765146.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049785863.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_049773171.1	5	Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668	"Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I"
XP_049787275.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_049772381.1	25	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049779052.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049782613.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049788400.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049766745.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049784458.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049767217.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049777162.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049774731.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_049777530.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049785640.1	37	Reactome: R-HSA-4615885;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-204005;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-2132295;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-983170;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531	"SUMOylation of DNA replication proteins";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"COPII-mediated vesicle transport";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"MHC class II antigen presentation";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus"
XP_049783747.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049785715.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049766683.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049778334.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049765774.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049785485.1	11	MetaCyc: PWY-381;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2	"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049766452.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884	"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX"
XP_049780333.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049764106.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049777372.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049777515.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049780754.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049770242.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049780622.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049765909.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049766657.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049785512.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049787097.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049776124.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_049769105.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation"
XP_049764103.1	6	Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3769402	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex"
XP_049765989.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880	"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases"
XP_049764832.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049785885.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049765480.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049762640.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_049762582.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049774886.1	6	Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)"
XP_049786395.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049774142.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049784914.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy"
XP_049770860.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049766447.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176408	"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase"
XP_049783231.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049773127.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049776683.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)"
XP_049783792.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049775515.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049775285.1	4	MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_049776841.1	12	KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-5744;MetaCyc: PWY-7854;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7118;MetaCyc: PWY-6969;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-6728;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294	"Glyoxylate and dicarboxylate metabolism";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Methylaspartate cycle";"Pyruvate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV"
XP_049781375.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049786961.1	9	Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18	"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes"
XP_049776423.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049787012.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110314	"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049787267.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049775820.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049773908.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Neutrophil degranulation";"COPII-mediated vesicle transport"
XP_049775961.1	4	KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_049777713.1	16	MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-5484	"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)"
XP_049774749.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049784144.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049767484.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin"
XP_049779265.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_049779978.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049773083.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation"
XP_049783740.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049777287.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049775116.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049769326.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049777075.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_049770428.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-4641262	"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_049784755.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049783899.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049773620.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049769688.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049783198.1	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_049785786.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_049762641.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_049784523.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049774869.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049779989.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049784128.1	7	Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-212300	"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA"
XP_049786494.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172	"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome"
XP_049763592.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049762496.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression"
XP_049762949.1	20	Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696397	"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049782677.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049770876.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049770536.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
XP_049786832.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049777558.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049785687.1	8	MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates"
XP_049784424.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049788202.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049784019.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-432142	"Chylomicron assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"LDL remodeling";"Scavenging by Class F Receptors";"VLDL assembly";"VLDL clearance";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"LDL clearance";"Scavenging by Class A Receptors";"Platelet sensitization by LDL"
XP_049770580.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049779868.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785784.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049767353.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation"
XP_049764572.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049763437.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049787178.1	14	Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049773784.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049787476.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049767266.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049781511.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049785111.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049771113.1	14	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism"
XP_049786530.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001	"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade"
XP_049767468.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_049775065.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049781633.1	5	Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism"
XP_049773151.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049763103.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049784918.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_049772436.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049768983.1	13	MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-7254;Reactome: R-HSA-71403	"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)"
XP_049786669.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_049783951.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049779527.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777487.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049788456.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049780523.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049767770.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049770241.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049780098.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049766516.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049779525.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785581.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_049785883.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049780448.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049771142.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_049769285.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049771950.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049762213.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049766508.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049770643.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049787432.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049770512.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049764114.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049781971.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049783256.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049788119.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049762296.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049778963.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049764971.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_049769813.1	12	Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-5250924	"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression"
XP_049776839.1	12	KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294;MetaCyc: PWY-5749;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-5744;MetaCyc: PWY-7854	"Pyruvate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV";"Itaconate degradation";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_049774027.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049782096.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049783354.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049773470.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049787138.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049773157.1	17	Reactome: R-HSA-937072;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-975163;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-9020702;Reactome: R-HSA-4086398	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Interleukin-1 signaling";"Ca2+ pathway"
XP_049771613.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049782704.1	5	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway"
XP_049777610.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049763077.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049780190.1	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049782824.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049776343.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049780269.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049764944.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049781712.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049780820.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049775699.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_049773626.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_049786700.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_049777764.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049786380.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049785971.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049785588.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049766070.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049776009.1	4	Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27	"Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation"
XP_049763599.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049765901.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884	"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX"
XP_049777696.1	6	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression"
XP_049785372.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049763058.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049773210.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049764777.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049777047.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049784503.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_049780123.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_049767813.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049784904.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_049783196.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049774410.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049775060.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049783678.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_049783962.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_049781451.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine"
XP_049787712.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050	"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_049783725.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049772862.1	12	Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9	"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_049780885.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049776409.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049786660.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049763584.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049784200.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049785457.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049781317.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049762778.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events"
XP_049764925.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049763832.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049783405.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_049779377.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049787826.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049784517.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049771663.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049786746.1	11	Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-69231	"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1"
XP_049778506.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049782153.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049762675.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049777828.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049775971.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation"
XP_049768751.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049766934.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state"
XP_049787481.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049769855.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049777126.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049785451.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049778646.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049783847.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049778801.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049783210.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049775810.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049784056.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport"
XP_049763055.1	14	Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049766272.1	5	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_049770624.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049780508.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049776798.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049766584.1	7	MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049763598.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism"
XP_049775838.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049763715.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049781306.1	12	KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-3801;MetaCyc: PWY-7343	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I"
XP_049784413.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629	"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_049777226.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049776248.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049779974.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049767050.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049787037.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049769803.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport"
XP_049786666.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049786544.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049778341.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049763228.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049766518.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049771563.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049767583.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049786999.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829	"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049772015.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049765064.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane"
XP_049780961.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_049767336.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049784604.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049763340.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Kinesins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_049786716.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049776812.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049785803.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785040.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049764849.1	14	MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049787945.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049769227.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049785842.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_049776498.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049778657.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049765689.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360	"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_049788103.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049784646.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049764775.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398	"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway"
XP_049762203.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_049785731.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049781829.1	5	MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049775115.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049776476.1	13	Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955	"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049783504.1	7	Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_049785328.1	8	KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_049762789.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_049764365.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors"
XP_049780669.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049777175.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049777311.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_049765004.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049774744.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049786546.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049776954.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049766406.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049765598.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049778586.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049780396.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049763685.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049786426.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_049780585.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300	"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling"
XP_049766835.1	12	KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142	"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049766049.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049774522.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049779271.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049784774.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049770733.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049776245.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049768814.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049787984.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049776342.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049763232.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049773779.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Iron uptake and transport";"UCH proteinases";"TGF-beta receptor signaling activates SMADs"
XP_049781895.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049782997.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049769549.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049769341.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049787472.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763137.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049777064.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781384.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049762471.1	20	KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726	"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_049783259.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049783539.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049782158.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049779495.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049780341.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049785132.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049781991.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049763817.1	10	Reactome: R-HSA-162699;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-913709;Reactome: R-HSA-4719377;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7661;MetaCyc: PWY-7921	"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"N-Glycan biosynthesis";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)"
XP_049785100.1	4	Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling"
XP_049783643.1	4	KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247	"Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids"
XP_049787443.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049779955.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049762234.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_049778417.1	6	Reactome: R-HSA-5083632;MetaCyc: PWY-7433;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_049762793.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_049765082.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049786488.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049781474.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression"
XP_049787189.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049787817.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049769275.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049787634.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049781841.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_049787483.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049766067.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049775312.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049784928.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049779061.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049784906.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159236	"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049778424.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049777239.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049777068.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049766287.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049778838.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049778511.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-2467813	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids"
XP_049784716.1	6	Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171	"Retinoid cycle disease events";"Amyloid fiber formation";"Retinoid metabolism and transport";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions"
XP_049782351.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049784817.1	7	MetaCyc: PWY-7185;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184	"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049779924.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049764144.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_049777229.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049786295.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049763610.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_049779972.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049783423.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049786833.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049777176.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049775516.1	17	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
XP_049779973.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049777511.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049763528.1	4	Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841	"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049766896.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049784384.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
XP_049778283.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049774523.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049786982.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_049771235.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_049776973.1	11	Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type"
XP_049766241.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049774789.1	33	Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464	"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of RNA binding proteins"
XP_049784376.1	8	MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate"
XP_049775270.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_049782154.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049771076.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049773703.1	6	MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_049777747.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049775791.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049781378.1	12	KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6309;MetaCyc: PWY-2821;MetaCyc: PWY-7901	"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine"
XP_049766719.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049781463.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049764701.1	7	Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-46	"Urea cycle";"Arginine biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Arginine and proline metabolism";"Urea cycle";"Putrescine biosynthesis III"
XP_049762655.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049765592.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049774143.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049784613.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049779116.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049771119.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049767822.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049780656.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049762422.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049764685.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism"
XP_049775090.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049787272.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049784590.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049775250.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049763666.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049786758.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049775839.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049786357.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049785248.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049773634.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049788153.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049779374.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049787939.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_049780952.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-167152;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery"
XP_049786489.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049768256.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049764670.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049769049.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870	"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins"
XP_049775046.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049777658.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049783559.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs"
XP_049775667.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049774239.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049784382.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)"
XP_049785603.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049776296.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049784994.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_049784052.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049788051.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_049776311.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049780901.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049787435.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049771864.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049766752.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049777754.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049780580.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-111932	"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB"
XP_049783105.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049787459.1	10	KEGG: 00410+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6537;Reactome: R-HSA-916853;MetaCyc: PWY-4321;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19;KEGG: 00250+2.6.1.19	"beta-Alanine metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II";"Degradation of GABA";"L-glutamate degradation IV";"4-aminobutanoate degradation I";"Butanoate metabolism";"4-aminobutanoate degradation V";"Propanoate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049777481.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_049768678.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049778381.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049773789.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_049787411.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049786766.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_049782001.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778613.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049763530.1	4	MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049774395.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049778385.1	31	MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-6799;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-6519;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;MetaCyc: PWY-6113	"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Pederin biosynthesis";"Mupirocin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"";"Oleate biosynthesis I (plants)";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis"
XP_049765681.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_049762598.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049773611.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_049779839.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049770947.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_049778372.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049785545.1	15	Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks"
XP_049783413.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049784272.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049777883.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049763105.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049762155.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049784412.1	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7922	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049777227.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049765244.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049787616.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049788372.1	52	Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV Transcription Initiation";"FGFR2 alternative splicing";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA"
XP_049774361.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-6811436	"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049766266.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_049782758.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049785565.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049782834.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_049775279.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049769967.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049787666.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049779888.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049773940.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK"
XP_049777795.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049775091.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049775529.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049776902.1	8	MetaCyc: PWY-5739;MetaCyc: PWY-5740;MetaCyc: PWY-7573;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47	"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism"
XP_049786706.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049774773.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049770666.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049787226.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_049788044.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049764405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049767476.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049777597.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049786143.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Gap junction assembly";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_049777847.1	6	Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;MetaCyc: PWY-7286	"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049763174.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049782945.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853	"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Synthesis of PC";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes"
XP_049763837.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation"
XP_049777893.1	4	MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism"
XP_049763749.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049787263.1	13	KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-6842;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112	"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification"
XP_049784872.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049778531.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049766221.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049774297.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049770762.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis"
XP_049781329.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049762845.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049778581.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_049780558.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049763419.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_049778777.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049771508.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049766018.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_049783886.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049780451.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049778018.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049779120.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049783137.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_049786830.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049778549.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049788296.1	7	KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-7805;MetaCyc: PWY-6605	"Purine metabolism";"Glyphosate degradation III";"Neutrophil degranulation";"Adenine salvage";"Purine salvage";"(aminomethyl)phosphonate degradation";"Adenine and adenosine salvage II"
XP_049783489.1	7	MetaCyc: PWY-6614;Reactome: R-HSA-1474151;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"Tetrahydrofolate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"One carbon pool by folate";"Folate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_049762567.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_049775479.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049780312.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049785612.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_049769211.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049775374.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049770587.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049774838.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049771951.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049778179.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049766438.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_049784545.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049776203.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049763319.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049776570.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049787845.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049787143.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-7182	"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I"
XP_049777581.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049783980.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049768124.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049787564.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049788245.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049776995.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171	"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis"
XP_049787981.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049780270.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049778738.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049768538.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049769166.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756	"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Synthesis of PC";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation"
XP_049781406.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049776115.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049773125.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_049778481.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049780388.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049762414.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049784392.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049778419.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_049773915.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049780660.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_049776880.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049767462.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_049768747.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049773666.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049763814.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_049765274.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049787768.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049770845.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049783317.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091	"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells"
XP_049776411.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049766985.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049775665.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation"
XP_049778723.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049767789.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049778655.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379	"ECM proteoglycans";"Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres"
XP_049768656.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049769947.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049778783.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_049765540.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Protein ubiquitination"
XP_049779001.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049784218.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049764878.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-168325	"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis"
XP_049784472.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049782684.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049763088.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049777808.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775998.1	11	MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42	"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism"
XP_049777221.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049781336.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049773101.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049785804.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049766011.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049778402.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_049772973.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049777225.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049778774.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049780037.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_049775283.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs"
XP_049775274.1	30	Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-2564830;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6781827	"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"mRNA Capping";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic iron-sulfur cluster assembly";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049780521.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_049763959.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049766618.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049784214.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049777050.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049772133.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049778340.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049768306.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049788397.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_049786893.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049785504.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049779987.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049773022.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8948751	"Protein ubiquitination";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity"
XP_049784715.1	10	Reactome: R-HSA-977225;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-3000171	"Amyloid fiber formation";"Retinoid metabolism and transport";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions"
XP_049769611.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049779851.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049786734.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049770084.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_049783920.1	6	Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15	"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Biotin metabolism"
XP_049782742.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049780653.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049780751.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_049768975.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695	"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation"
XP_049782149.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_049776893.1	8	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_049788491.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777742.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049763698.1	179	Reactome: R-HSA-2644606;Reactome: R-HSA-5693565;Reactome: R-HSA-5684264;Reactome: R-HSA-2122948;Reactome: R-HSA-156827;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-937041;Reactome: R-HSA-2173791;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8876493;Reactome: R-HSA-9646399;Reactome: R-HSA-8854050;Reactome: R-HSA-4641263;Reactome: R-HSA-983168;Reactome: R-HSA-2559580;Reactome: R-HSA-5656169;Reactome: R-HSA-450321;Reactome: R-HSA-5696395;Reactome: R-HSA-3134975;Reactome: R-HSA-936440;Reactome: R-HSA-5696397;Reactome: R-HSA-9013507;Reactome: R-HSA-917937;Reactome: R-HSA-917729;Reactome: R-HSA-6804760;Reactome: R-HSA-1253288;Reactome: R-HSA-2408557;Reactome: R-HSA-174184;Reactome: R-HSA-2691232;Reactome: R-HSA-5675221;Reactome: R-HSA-936964;Reactome: R-HSA-1236974;Reactome: R-HSA-156902;Reactome: R-HSA-5685942;Reactome: R-HSA-5689901;Reactome: R-HSA-205043;Reactome: R-HSA-1799339;Reactome: R-HSA-6807004;Reactome: R-HSA-2559582;Reactome: R-HSA-2894862;Reactome: R-HSA-532668;Reactome: R-HSA-8852276;Reactome: R-HSA-1295596;Reactome: R-HSA-9033241;Reactome: R-HSA-5668541;Reactome: R-HSA-6783310;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-5656121;Reactome: R-HSA-937072;Reactome: R-HSA-72764;Reactome: R-HSA-6804756;Reactome: R-HSA-5610780;Reactome: R-HSA-6781827;Reactome: R-HSA-9013973;Reactome: R-HSA-1358803;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-5654727;Reactome: R-HSA-8866652;Reactome: R-HSA-5655862;Reactome: R-HSA-75815;Reactome: R-HSA-2122947;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8866654;Reactome: R-HSA-5654726;Reactome: R-HSA-69541;Reactome: R-HSA-2173788;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-5654732;Reactome: R-HSA-174048;Reactome: R-HSA-975163;Reactome: R-HSA-8856828;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-1236382;Reactome: R-HSA-174490;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-2173796;Reactome: R-HSA-5696394;Reactome: R-HSA-182971;Reactome: R-HSA-2173795;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-6781823;Reactome: R-HSA-1169408;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-68827;Reactome: R-HSA-2672351;Reactome: R-HSA-110312;Reactome: R-HSA-400253;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-5675482;Reactome: R-HSA-5362768;Reactome: R-HSA-175474;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-975956;Reactome: R-HSA-209543;Reactome: R-HSA-174084;Reactome: R-HSA-8948747;Reactome: R-HSA-9615710;Reactome: R-HSA-110320;Reactome: R-HSA-162588;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-179409;Reactome: R-HSA-9637628;Reactome: R-HSA-168928;Reactome: R-HSA-912631;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-5205685;Reactome: R-HSA-68949;Reactome: R-HSA-8875360;Reactome: R-HSA-3785653;Reactome: R-HSA-8863795;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-975110;Reactome: R-HSA-6804757;Reactome: R-HSA-9613829;Reactome: R-HSA-1169091;Reactome: R-HSA-201681;Reactome: R-HSA-901032;Reactome: R-HSA-9014325;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-3769402;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-6782135;Reactome: R-HSA-9010553;Reactome: R-HSA-5654733;Reactome: R-HSA-180585;Reactome: R-HSA-8849469;Reactome: R-HSA-4641258;Reactome: R-HSA-209560;Reactome: R-HSA-5689896;Reactome: R-HSA-1234176;Reactome: R-HSA-5696400;Reactome: R-HSA-3322077;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2565942;Reactome: R-HSA-69481;Reactome: R-HSA-168927;Reactome: R-HSA-5689877;Reactome: R-HSA-937039;Reactome: R-HSA-192823;Reactome: R-HSA-2979096;Reactome: R-HSA-110314;Reactome: R-HSA-8856825;Reactome: R-HSA-5610785;Reactome: R-HSA-9636383;Reactome: R-HSA-8951664;Reactome: R-HSA-2559585;Reactome: R-HSA-9604323;Reactome: R-HSA-6791226;Reactome: R-HSA-450302;Reactome: R-HSA-8948751;Reactome: R-HSA-168638;Reactome: R-HSA-5610783	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activated NOTCH1 Transmits Signal to the Nucleus";"L13a-mediated translational silencing of Ceruloplasmin expression";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"IKK complex recruitment mediated by RIP1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"InlA-mediated entry of Listeria monocytogenes into host cells";"Aggrephagy";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of FZD by ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxidative Stress Induced Senescence";"Termination of translesion DNA synthesis";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Formation of Incision Complex in GG-NER";"Regulation of innate immune responses to cytosolic DNA";"Negative regulators of DDX58/IFIH1 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Iron uptake and transport";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of TP53 Activity through Methylation";"Downregulation of ERBB4 signaling";"Selenocysteine synthesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Negative regulation of MAPK pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"ER-Phagosome pathway";"Peptide chain elongation";"HDR through Homologous Recombination (HRR)";"Metalloprotease DUBs";"NRIF signals cell death from the nucleus";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of MET activity";"Senescence-Associated Secretory Phenotype (SASP)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Spry regulation of FGF signaling";"Peroxisomal protein import";"TNFR2 non-canonical NF-kB pathway";"Fanconi Anemia Pathway";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Translesion synthesis by POLI";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Eukaryotic Translation Termination";"Regulation of TP53 Activity through Phosphorylation";"Degradation of GLI1 by the proteasome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of ERBB2:ERBB3 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Negative regulation of FGFR2 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Translesion synthesis by POLK";"Ubiquitin-dependent degradation of Cyclin D";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Negative regulation of FGFR1 signaling";"Stabilization of p53";"Downregulation of TGF-beta receptor signaling";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Negative regulation of FGFR3 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Clathrin-mediated endocytosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Membrane binding and targetting of GAG proteins";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"DNA Damage Recognition in GG-NER";"EGFR downregulation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Formation of TC-NER Pre-Incision Complex";"ISG15 antiviral mechanism";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CDT1 association with the CDC6:ORC:origin complex";"Stimuli-sensing channels";"Translesion synthesis by REV1";"Circadian Clock";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"Regulation of necroptotic cell death";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Assembly Of The HIV Virion";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"p75NTR recruits signalling complexes";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN localization";"Late endosomal microautophagy";"Translesion Synthesis by POLH";"Budding and maturation of HIV virion";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"APC-Cdc20 mediated degradation of Nek2A";"Modulation by Mtb of host immune system";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of signaling by CBL";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"Pink/Parkin Mediated Mitophagy";"Orc1 removal from chromatin";"InlB-mediated entry of Listeria monocytogenes into host cell";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB2 signaling";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of TP53 Degradation";"Chaperone Mediated Autophagy";"Activation of NF-kappaB in B cells";"TCF dependent signaling in response to WNT";"ER Quality Control Compartment (ERQC)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Deactivation of the beta-catenin transactivating complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Dual incision in TC-NER";"Regulation of expression of SLITs and ROBOs";"Negative regulation of FGFR4 signaling";"Vif-mediated degradation of APOBEC3G";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Degradation of DVL";"NF-kB is activated and signals survival";"Ovarian tumor domain proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dual Incision in GG-NER";"Glycogen synthesis";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of PLK1 Activity at G2/M Transition";"G2/M Checkpoints";"TICAM1, RIP1-mediated IKK complex recruitment";"Josephin domain DUBs";"IRAK1 recruits IKK complex";"Viral mRNA Translation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Recognition of DNA damage by PCNA-containing replication complex";"Cargo recognition for clathrin-mediated endocytosis";"GLI3 is processed to GLI3R by the proteasome";"Prevention of phagosomal-lysosomal fusion";"Neddylation";"Oncogene Induced Senescence";"Negative regulation of NOTCH4 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"activated TAK1 mediates p38 MAPK activation";"Regulation of PTEN stability and activity";"NOD1/2 Signaling Pathway";"Degradation of GLI2 by the proteasome"
XP_049765026.1	5	KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527	"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation"
XP_049766837.1	12	MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism"
XP_049762677.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049762748.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049782021.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049766446.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-179409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A"
XP_049763229.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049767111.1	25	Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-437239	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recycling pathway of L1"
XP_049782585.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049765671.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_049786978.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049786491.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049773740.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_049784145.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049767034.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_049765161.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling"
XP_049765285.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-8001	"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_049763971.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049785331.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049773823.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4615885	"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins"
XP_049784548.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049773942.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049778363.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049775682.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049764998.1	18	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-166208;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTORC1-mediated signalling";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation"
XP_049762773.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_049784778.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049780592.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692	"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ion homeostasis";"Regulation of MECP2 expression and activity"
XP_049787266.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049782404.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049763457.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049785051.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049781769.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049783101.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049785755.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049779617.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049775303.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049762156.1	13	Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52	"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation"
XP_049781757.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049765822.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049763158.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049778271.1	6	KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52	"Methane metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism"
XP_049765287.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514	"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049785729.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049771454.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049780382.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049772895.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049768916.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8939243	"Signal transduction by L1";"Synthesis of PC";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049777827.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049765916.1	5	MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
XP_049773862.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_049786525.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049770951.1	6	KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52	"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Cysteine and methionine metabolism"
XP_049777636.1	17	KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6608;Reactome: R-HSA-6798695	"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Neutrophil degranulation"
XP_049767690.1	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
XP_049781689.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049786834.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049777230.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049777978.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049778326.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049775071.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049763110.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049778948.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049779459.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049771218.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049771079.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049780760.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049783213.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition"
XP_049781975.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001	"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_049776163.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049763207.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049773133.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049785990.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049778719.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_049777512.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049765247.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049782059.1	4	KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;KEGG: 00010+3.1.3.9;Reactome: R-HSA-70263	"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_049773534.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049784186.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049762941.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_049776797.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049780039.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049775440.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049762633.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049773822.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-168333	"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049774853.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049783714.1	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_049773381.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049764974.1	5	MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;MetaCyc: PWY-7391	"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)"
XP_049773165.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-176407	"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049764119.1	6	Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700	"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling"
XP_049784302.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049786763.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049785696.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049777276.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_049781896.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049764643.1	4	Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400	"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049781990.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049786941.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049767773.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049774199.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049767099.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049779870.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774981.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049774750.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049773364.1	8	Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066	"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049773717.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049781514.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049764973.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049783026.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049776784.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049785465.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049781610.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049784807.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049767891.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049768736.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049768134.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049786392.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049786827.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049787480.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049780732.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049780457.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049784007.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049784422.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-975871	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane"
XP_049763374.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049774161.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659	"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis"
XP_049783691.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_049763112.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049767131.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049779808.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541	"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway"
XP_049786912.1	2	Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049777998.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049764833.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049766492.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049784887.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-210747	"Regulation of gene expression in beta cells";"Regulation of gene expression in early pancreatic precursor cells"
XP_049766507.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049764798.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13	"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_049763603.1	14	MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6969	"Methylaspartate cycle";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049768340.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049773870.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049779155.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_049769801.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049764913.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049777994.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049764105.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049764706.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049765232.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049784591.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049787663.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049773947.1	4	KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221	"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis"
XP_049774860.1	13	MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-6370;MetaCyc: PWY-2261;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1	"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism"
XP_049766061.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_049773619.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049776190.1	4	MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_049782033.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049776159.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_049786129.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049787824.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_049775477.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049783896.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049782967.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049778158.1	18	MetaCyc: PWY-5913;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1	"Partial TCA cycle (obligate autotrophs)";"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism"
XP_049773517.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049769212.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049785009.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049777418.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049775478.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049784881.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049775558.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_049775220.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049776906.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_049779928.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049784399.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049788005.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049767668.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_049779703.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049787069.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049780126.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_049765680.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_049778615.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
YP_010401627.1	7	Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2;MetaCyc: PWY-4302;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;MetaCyc: PWY-5083;MetaCyc: PWY-3781	"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Fe(II) oxidation";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)"
XP_049778121.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049766506.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049774735.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049773230.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049778035.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049777720.1	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049766265.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049773409.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766574.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049767038.1	7	KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism"
XP_049767738.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_049763579.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049773933.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049763662.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049776076.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787530.1	11	KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9	"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine metabolism"
XP_049765262.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049762481.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049783345.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049763659.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049763746.1	33	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-69202;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-72086	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Cyclin E associated events during G1/S transition";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"mRNA Capping"
XP_049765940.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049768273.1	5	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway"
XP_049783562.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049782530.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049774833.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049770799.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049769048.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases"
XP_049788084.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049782593.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049766799.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_049780373.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049766708.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049767775.1	12	KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1861	"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_049774954.1	3	Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269	"Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_049776925.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)"
XP_049772363.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_049767256.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049773659.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_049762629.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049783199.1	6	MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_049770850.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049766668.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5628897	"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes"
XP_049781426.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_049764207.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049786694.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049786695.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049776735.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049787269.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049773055.1	5	MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4	"Mevalonate degradation";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism"
XP_049780913.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049766394.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049775932.1	7	Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790	"Pyrimidine biosynthesis";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II"
XP_049779078.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_049780464.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049779153.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_049778523.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049786241.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049775100.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049786959.1	9	KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842	"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_049785776.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049778429.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049785598.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778428.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049780897.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049786940.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049780890.1	9	MetaCyc: PWY-6322;MetaCyc: PWY-7769;KEGG: 00440+4.1.1.82;MetaCyc: PWY-6839;MetaCyc: PWY-7510;KEGG: 00998+4.1.1.82;MetaCyc: PWY-5757;MetaCyc: PWY-6682;MetaCyc: PWY-8067	"Phosphinothricin tripeptide biosynthesis";"Phosalacine biosynthesis";"Phosphonate and phosphinate metabolism";"2-aminoethylphosphonate biosynthesis";"Rhizocticin A and B biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Fosfomycin biosynthesis";"Dehydrophos biosynthesis";"Methylphosphonate biosynthesis"
XP_049780267.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049773186.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049766756.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049777248.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049768708.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049783855.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695	"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation"
XP_049785059.1	7	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_049785737.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049764094.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049766175.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_049766572.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049785422.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952	"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation"
XP_049783124.1	3	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_049764851.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972	"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)"
XP_049762646.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049765628.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049765048.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049764068.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049772468.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049786907.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_049763848.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049782725.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049763512.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049781900.1	5	KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;Reactome: R-HSA-389661;MetaCyc: PWY-5046	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA"
XP_049780051.1	5	MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_049771068.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049785805.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049776579.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_049784927.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049780359.1	10	KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7411	"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)"
XP_049783232.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049780623.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049786057.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25	"Neutrophil degranulation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049787782.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049763390.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049788283.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167246	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript"
XP_049774870.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049788046.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
XP_049787569.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049775692.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049769157.1	29	Reactome: R-HSA-3108214;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-912446	"SUMOylation of DNA damage response and repair proteins";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Meiotic recombination"
XP_049782335.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049783677.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049763527.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049787486.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783220.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049786507.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049778910.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049780304.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049781376.1	12	KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-6936;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187	"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine"
XP_049762821.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049777908.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049773787.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049776993.1	10	MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Glycolysis";"Pentose phosphate pathway"
XP_049777363.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049768714.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049787107.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049767532.1	52	Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-73762	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"FGFR2 alternative splicing";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation"
XP_049778656.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_049767500.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint"
XP_049782944.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Synthesis of PC";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes"
XP_049763010.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
XP_049764017.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
XP_049763214.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049766760.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049767472.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049785695.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418594	"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events"
XP_049782709.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049777194.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049776746.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783482.1	24	Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-9009391	"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling"
XP_049778303.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049774306.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_049781314.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_049785109.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049787038.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049773584.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_049780821.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049783211.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-171306	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends"
XP_049765155.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049765096.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049781876.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049778973.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049785257.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049763502.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049769059.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_049779614.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049766938.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049773913.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049767802.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049768859.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_049770671.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_049774098.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049783060.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049766763.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049778251.1	29	Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511	"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Meiotic recombination";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation"
XP_049769817.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-73762;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049781433.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049786495.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation"
XP_049784136.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049780452.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049763070.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049767823.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049771617.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049773790.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_049765044.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_049783903.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049785501.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049778480.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049774799.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049779667.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049773842.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049777710.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049766805.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049784131.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049773108.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_049764664.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049784983.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049774516.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049771504.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049766522.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049772252.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049776745.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049778689.1	4	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049787162.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049772060.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049763909.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049778814.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049777357.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049782152.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049783319.1	8	MetaCyc: PWY-5154;MetaCyc: PWY-4984;KEGG: 00220+6.3.4.5;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-5	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Canavanine biosynthesis"
XP_049777302.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049781823.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis"
XP_049783981.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049775064.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049777151.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049767853.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049781394.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049767087.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049777497.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)"
XP_049779771.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_049763750.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049769950.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049769938.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049772452.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049783901.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049780484.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049768132.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049784437.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049773948.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049770626.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049773995.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049767798.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51	"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_049763254.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049781365.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049774043.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049787615.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049787802.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_049781813.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049776977.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049776268.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049765224.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049785174.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-5358346	"Protein ubiquitination";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis"
XP_049771591.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049785452.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049766057.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_049775740.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_049785886.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049780419.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049776002.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_049786929.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490	"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation"
XP_049778784.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049778791.1	8	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"HCMV Early Events"
XP_049786710.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049780681.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049782698.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049774074.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049778740.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049782916.1	7	Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_049777030.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_049786076.1	10	Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505	"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049766440.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis"
XP_049776810.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049770949.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049780512.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509	"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Chromatin modifying enzymes"
XP_049763119.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049778474.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049767458.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_049779014.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049763375.1	22	MetaCyc: PWY-7238;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5384;KEGG: 00500+5.3.1.9;MetaCyc: PWY-621;Reactome: R-HSA-70263;MetaCyc: PWY-5659;MetaCyc: PWY-8013;KEGG: 00010+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-7385;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5514;Reactome: R-HSA-6798695;MetaCyc: PWY-622;Reactome: R-HSA-70171;MetaCyc: PWY-5054;MetaCyc: PWY-6992;MetaCyc: PWY-6142;MetaCyc: PWY-6981;Reactome: R-HSA-5628897	"Sucrose biosynthesis II";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation IV (sucrose phosphorylase)";"Starch and sucrose metabolism";"Sucrose degradation III (sucrose invertase)";"Gluconeogenesis";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis / Gluconeogenesis";"Sucrose degradation II (sucrose synthase)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neutrophil degranulation";"Starch biosynthesis";"Glycolysis";"D-sorbitol biosynthesis I";"1,5-anhydrofructose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Chitin biosynthesis";"TP53 Regulates Metabolic Genes"
XP_049767451.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049784626.1	11	MetaCyc: PWY-922;MetaCyc: PWY-7560;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-6174;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-7391;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7524	"Mevalonate pathway I";"Methylerythritol phosphate pathway II";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway III (archaea)"
XP_049777724.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_049763436.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-3232142	"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"SUMOylation of ubiquitinylation proteins"
XP_049773438.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049776401.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_049765400.1	14	KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5057;MetaCyc: PWY-7767;MetaCyc: PWY-5076;Reactome: R-HSA-70895;MetaCyc: PWY-5101	"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-leucine degradation III";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis II"
XP_049775744.1	57	Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs"
XP_049778575.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049777715.1	16	MetaCyc: PWY-5723;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11	"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis"
XP_049776760.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049774792.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049769636.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049783846.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049773745.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049766443.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_049762806.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_049775597.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049785798.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049767464.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_049784665.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049775793.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_049783919.1	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Biotin transport and metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049764680.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049769732.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049779515.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049785454.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049780357.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049781536.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049775523.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_049784757.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049764932.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049770534.1	6	MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124	"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II"
XP_049762747.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049778388.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-2559586	"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence"
XP_049767030.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049783258.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049772904.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049787630.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition"
XP_049783770.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049783396.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049779869.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775823.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049765306.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway"
XP_049763225.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049778756.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049788259.1	5	Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883	"Triglyceride biosynthesis";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG"
XP_049787319.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080	"Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)"
XP_049777701.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049768254.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049782597.1	52	Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-76066;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-76061;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-73762;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-75953;Reactome: R-HSA-112382	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"FGFR2 alternative splicing";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex"
XP_049787278.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049779370.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049777283.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049787431.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049766573.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049779266.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_049776074.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049774829.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049785180.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049779031.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049766621.1	10	MetaCyc: PWY-7996;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5839	"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis"
XP_049777456.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049774449.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049786067.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049767952.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049775985.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049780043.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049766024.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049781972.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049775669.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049767490.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049764690.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049781747.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049783490.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1474151;MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3	"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate biosynthesis"
XP_049777342.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_049765233.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049763359.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049783180.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049763977.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049774073.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049765675.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049773582.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_049781831.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049766672.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049782946.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes"
XP_049765090.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049767565.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049785807.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_049774089.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049784380.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049775372.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049783835.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049767291.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049774777.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_049785641.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049785036.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049777323.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049787561.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049786895.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049774287.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-159236	"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049776638.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049787829.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049768915.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Synthesis of PC";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL"
XP_049784277.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_049778943.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049772986.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049786769.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049766984.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049784736.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049780870.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis"
XP_049764673.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049787937.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5872;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_049781863.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049767269.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049765813.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049765057.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049767109.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049767756.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049782793.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_049786577.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049774117.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-2301;MetaCyc: PWY-6664	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis"
XP_049781840.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_049787604.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049781346.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049765545.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049783584.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049780328.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049784587.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049781339.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049773934.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049784443.1	7	Reactome: R-HSA-1989781;KEGG: 00071+1.3.8.7;Reactome: R-HSA-77288;KEGG: 00280+1.3.8.7;Reactome: R-HSA-77346;MetaCyc: PWY-7094;Reactome: R-HSA-77348	"PPARA activates gene expression";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Valine, leucine and isoleucine degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid salvage";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA"
XP_049771543.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049773139.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049779649.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_049783696.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049778530.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_049787940.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_049774512.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049773737.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049763733.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049778944.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049786711.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049771130.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049768895.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049770765.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
YP_010401621.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049774803.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_049776987.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_049765556.1	7	MetaCyc: PWY-7118;MetaCyc: PWY-6969;MetaCyc: PWY-7295;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7854;KEGG: 00630+2.3.3.9	"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV";"Pyruvate metabolism";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate and dicarboxylate metabolism"
XP_049768898.1	29	Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-3108214;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606	"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"Meiotic recombination";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"SUMOylation of DNA damage response and repair proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049763769.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049786948.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049768740.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049775693.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049787692.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049782832.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049762423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049773773.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049785258.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition"
XP_049774136.1	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
XP_049780611.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049785523.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049774868.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049778588.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_049780953.1	15	Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796	"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_049783102.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_049788156.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049783360.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049771984.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049783881.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049781269.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049768321.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049768774.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049779121.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049773366.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049787404.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049787042.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049763752.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049784253.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049771173.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049766028.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497	"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049771098.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049784436.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049778122.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049786881.1	8	MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-7400;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_049785505.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_049784536.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049785056.1	57	Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949	"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Neddylation";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin"
XP_049780650.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049783867.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049771614.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049784289.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-9009391	"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling"
XP_049784875.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049785115.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670	"MHC class II antigen presentation";"Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis"
XP_049768869.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049778750.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049778422.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110329	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine"
XP_049785392.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049764253.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_049770898.1	15	KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-6901	"Purine metabolism";"Glycolysis";"Rubisco shunt";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation"
XP_049785916.1	5	KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983	"Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)"
XP_049775503.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764	"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling"
XP_049775763.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049772506.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049782900.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049784727.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049765777.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049781956.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049782734.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_049764251.1	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;MetaCyc: PWY-5265;Reactome: R-HSA-446193;Reactome: R-HSA-4549356	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2"
XP_049765817.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049775605.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430	"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation"
XP_049762727.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049767605.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049774545.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049773346.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_049764778.1	22	Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7606;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6958;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_049777224.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049784270.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049777479.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049768948.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049768856.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049788057.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049768922.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049776114.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_049776685.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6	"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism"
XP_049775549.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049765789.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049775819.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049776958.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735	"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis"
XP_049769815.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-73762	"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation"
XP_049768949.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781041.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049763117.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049787669.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049766455.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176409	"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_049775559.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_049771529.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049770645.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049780505.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049762240.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_049781858.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing"
XP_049770897.1	15	MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-6901	"Rubisco shunt";"Purine metabolism";"Glycolysis";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation"
XP_049781595.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434	"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049777282.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049774619.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049763440.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049769629.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049779105.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049778254.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Factors involved in megakaryocyte development and platelet production";"PKA activation";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_049777560.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049775326.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049780326.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049777031.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-3108214	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"SUMOylation of DNA damage response and repair proteins"
XP_049764930.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049777986.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_049780383.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773082.1	32	Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75953	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"FGFR2 alternative splicing";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation"
XP_049774028.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049775765.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049785354.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_049782629.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041	"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"LDL clearance";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"VLDL clearance";"VLDL assembly";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL remodeling"
XP_049764943.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049779004.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049763962.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049773826.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159236	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049778648.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049782576.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049786823.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049787167.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049770998.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049779348.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049764698.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049784431.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049780806.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation"
XP_049773985.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049768368.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049773926.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049780684.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049770670.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_049783440.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_049778574.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049777665.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049778010.1	11	Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049764972.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_049776771.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049765551.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_049779544.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049780689.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049773889.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Cargo concentration in the ER";"Neutrophil degranulation";"COPII-mediated vesicle transport"
XP_049763305.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815	"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D"
XP_049763496.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_049767743.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_049767459.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049780649.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049764425.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049785483.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_049774130.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-0;MetaCyc: PWY-6117	"Arginine and proline metabolism";"Putrescine degradation III";"Spermine and spermidine degradation I"
XP_049767252.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049785743.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049774468.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049775795.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049775752.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049766514.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049778458.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_049783832.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049787145.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049783152.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049767085.1	57	Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5658442	"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs"
XP_049786238.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049782240.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049767547.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049775222.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049787763.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049786572.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049780522.1	13	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913	"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)"
XP_049774709.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049780125.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_049770238.1	19	Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-5663220;Reactome: R-HSA-114604;Reactome: R-HSA-5626467;Reactome: R-HSA-428543;Reactome: R-HSA-5625970;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-525793;Reactome: R-HSA-182971	"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"RHO GTPases Activate Formins";"GPVI-mediated activation cascade";"RHO GTPases activate IQGAPs";"Inactivation of CDC42 and RAC1";"RHO GTPases activate KTN1";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Myogenesis";"EGFR downregulation"
XP_049778006.1	2	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_049763858.1	1	Reactome: R-HSA-5673001	"RAF/MAP kinase cascade"
XP_049782933.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049773901.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"Neutrophil degranulation";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_049784140.1	15	Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9634285;Reactome: R-HSA-9664565;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9652282;Reactome: R-HSA-9665249;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795;Reactome: R-HSA-9665247	"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib"
XP_049782932.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049768023.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049770315.1	11	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172	"Ub-specific processing proteases";"HATs acetylate histones";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome"
XP_049785630.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049769198.1	9	KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-6146	"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_049767834.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049763216.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy"
XP_049784217.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049788409.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049777520.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Glutathione metabolism"
XP_049765134.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049764300.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049767199.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049768154.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_049763320.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049786456.1	5	MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527	"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation"
XP_049764583.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049768559.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-349425	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049775890.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049765053.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049785228.1	3	Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807	"Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling"
XP_049787193.1	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049781395.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049779697.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049786639.1	13	Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-2871796;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-202433;Reactome: R-HSA-2871809;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-2424491	"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated MAPK activation";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Generation of second messenger molecules";"FCERI mediated Ca+2 mobilization";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"DAP12 signaling"
XP_049786060.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_049783718.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049766444.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_049788170.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049787284.1	13	Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-4061	"Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I"
XP_049778099.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049776929.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049783874.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049775444.1	58	Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-5689901;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236	"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Metalloprotease DUBs";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049763632.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049781480.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049779165.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049770896.1	15	MetaCyc: PWY-5723;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-6901	"Rubisco shunt";"Glycolysis";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation"
XP_049768874.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049781335.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049783083.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049786761.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049782150.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049774858.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049768297.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049763771.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis"
XP_049772493.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049776875.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049783426.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049780984.1	4	Reactome: R-HSA-6807047;MetaCyc: PWY-8026;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis"
XP_049763748.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049785460.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049781770.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049775301.1	4	KEGG: 00340+3.5.2.7;MetaCyc: PWY-5028;MetaCyc: PWY-5030;Reactome: R-HSA-70921	"Histidine metabolism";"L-histidine degradation II";"L-histidine degradation III";"Histidine catabolism"
XP_049772399.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049786527.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049775887.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049779091.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049771854.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049766537.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_049780114.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049766743.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049785966.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes"
XP_049770777.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664	"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Neddylation"
XP_049768419.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049786934.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787397.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049787338.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049784023.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049770116.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049780838.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049773382.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_049787485.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049764336.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049763226.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049783682.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_049768896.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049777473.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system"
XP_049785812.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049786751.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049781790.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049777672.1	24	Reactome: R-HSA-114604;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5625740	"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Activation of AKT2";"Regulation of TP53 Degradation";"mTOR signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"Thermogenesis";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"RSK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"RHO GTPases activate PKNs"
XP_049775790.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_049782555.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049782009.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_049786924.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049779829.1	9	Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway"
XP_049787609.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049787261.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049785081.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049768060.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049766478.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049764555.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049785569.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049781405.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049776923.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism"
XP_049767765.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049774064.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_049773176.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049762406.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049766986.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049776680.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7574	"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II"
XP_049768746.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049765948.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049774222.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049785387.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049762673.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049777791.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049775599.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049773154.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049777967.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_049787570.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049764167.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy"
XP_049774738.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049778126.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049773633.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049769186.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049783022.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049787160.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049771263.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049776157.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade"
XP_049784037.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049780782.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_049782325.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)"
XP_049768313.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049770669.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_049786252.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049763231.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049765642.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_049776657.1	5	Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_049786144.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811436	"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"Mitotic Prometaphase";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049766530.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049781933.1	16	KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5749;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.4;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5537	"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Itaconate degradation";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V"
XP_049783572.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049782138.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_049767766.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049782903.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049780762.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_049775073.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049774053.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049768230.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049773521.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049788246.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049780593.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9620244	"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation"
XP_049782340.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049782737.1	5	Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
XP_049784400.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_049763784.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049770563.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049781845.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049784316.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049777500.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-159236	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049785092.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049778616.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049784564.1	17	Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)"
XP_049777859.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049777025.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049766048.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049786640.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049785421.1	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_049786635.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049769646.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-429947	"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_049787009.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049778332.1	5	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_049777770.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049762628.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049778462.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_049762774.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049787465.1	33	Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_049776744.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049778160.1	18	KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1	"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism"
XP_049766680.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049775916.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049778060.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049766927.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria"
XP_049767444.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049765402.1	14	KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5104;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5103;MetaCyc: PWY-5101;Reactome: R-HSA-70895;MetaCyc: PWY-5076;MetaCyc: PWY-7767	"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"Cysteine and methionine metabolism";"L-valine degradation II";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"L-leucine degradation III";"L-leucine degradation IV (Stickland reaction)"
XP_049766059.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049769812.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-73762;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049775327.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049778839.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049774753.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049777655.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049778832.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049783956.1	7	Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-4641258	"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"PCP/CE pathway";"Degradation of DVL"
XP_049787262.1	32	Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-6807505	"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"FGFR2 alternative splicing";"HIV Transcription Initiation";"mRNA Capping";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes"
XP_049779371.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049767607.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_049765629.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049769287.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049780347.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049766534.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049763057.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049785510.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049765795.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049786997.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049776238.1	66	Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-176408;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-8853884;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-176407;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-176409;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-1236974	"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Regulation of APC/C activators between G1/S and early anaphase";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Transcriptional Regulation by VENTX";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of mitotic proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"ER-Phagosome pathway"
XP_049765584.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049770959.1	10	KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_049782683.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049780992.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2"
XP_049776938.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049780432.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049763630.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049770537.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
XP_049782011.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049776980.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049771067.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
XP_049782000.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049774279.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049783582.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049764659.1	40	KEGG: 00360+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00640+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7726;MetaCyc: PWY-7401;MetaCyc: PWY-7216;MetaCyc: PWY-5789;MetaCyc: PWY-5109;MetaCyc: PWY-7656;KEGG: 00903+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-6435;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-1361;MetaCyc: PWY-6883;KEGG: 00380+4.2.1.17+1.1.1.35	"Phenylalanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"Propanoate metabolism";"Caprolactam degradation";"Fatty acid elongation";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Glutaryl-coa degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fermentation to 2-methylbutanoate";"Spodoptera littoralis pheromone biosynthesis";"Limonene and pinene degradation";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Lysine degradation";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid salvage";"Butanoate metabolism";"Geraniol degradation";"2-methylpropene degradation";"Toluene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to butanol II (engineered)";"Tryptophan metabolism"
XP_049776783.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049766616.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049778901.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
XP_049782871.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_049782938.1	5	Reactome: R-HSA-1237112;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109	"Methionine salvage pathway";"Formation of apoptosome";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049774618.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049784518.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049782935.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049763293.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049774540.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049777214.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049784597.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049784149.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049766684.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049788180.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049788377.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_049766395.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049774968.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049784929.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_049764008.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049773795.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_049783868.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049786662.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049788477.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_049784435.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049767296.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049763529.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049770457.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049764855.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049779490.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049787320.1	13	MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7182	"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I"
XP_049787760.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049781036.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049776827.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049777375.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049775764.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049775417.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049774989.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049772237.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049781575.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_049778776.1	3	KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_049778563.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049778595.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049781065.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049762185.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049770771.1	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_049788096.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049776522.1	12	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis"
XP_049773402.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049782680.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049776895.1	8	Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049775734.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049777135.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Caspase activation via Dependence Receptors in the absence of ligand";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049763714.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_049775238.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12	"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)"
XP_049777284.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049765979.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049777855.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049779227.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049777003.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049785772.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049773660.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049775265.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049765145.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049764526.1	43	Reactome: R-HSA-202670;Reactome: R-HSA-5358747;Reactome: R-HSA-163767;Reactome: R-HSA-2995383;Reactome: R-HSA-69231;Reactome: R-HSA-5358752;Reactome: R-HSA-8854518;Reactome: R-HSA-5467348;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-2465910;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-69273;Reactome: R-HSA-180024;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-9634600;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-113501;Reactome: R-HSA-198753;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-975957;Reactome: R-HSA-380284;Reactome: R-HSA-1295596;Reactome: R-HSA-6804757;Reactome: R-HSA-163685;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-195253	"ERKs are inactivated";"S33 mutants of beta-catenin aren't phosphorylated";"PP2A-mediated dephosphorylation of key metabolic factors";"Initiation of Nuclear Envelope Reformation";"Cyclin D associated events in G1";"T41 mutants of beta-catenin aren't phosphorylated";"AURKA Activation by TPX2";"Truncations of AMER1 destabilize the destruction complex";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"MASTL Facilitates Mitotic Progression";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin A/B1/B2 associated events during G2/M transition";"DARPP-32 events";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"ERK/MAPK targets";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Spry regulation of FGF signaling";"Regulation of TP53 Degradation";"Integration of energy metabolism";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex"
XP_049764074.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049775547.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049763831.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049779127.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049764827.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049786056.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049770925.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_049763376.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049782156.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049778068.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049764042.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049771194.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_049788474.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049772100.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049787667.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049784132.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by Hippo";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049776918.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049764861.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049777829.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459	"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049766449.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-179409	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A"
XP_049781786.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049773503.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049776874.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049782841.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_049766503.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049777219.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049788212.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049766513.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049783477.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I"
XP_049784426.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049780646.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
YP_010401626.1	7	MetaCyc: PWY-4302;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;MetaCyc: PWY-3781;MetaCyc: PWY-5083;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2	"Aerobic respiration III (alternative oxidase pathway)";"Fe(II) oxidation";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Oxidative phosphorylation"
XP_049777837.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049774252.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049765888.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_049787789.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049783146.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049773986.1	14	KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1	"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Oxidative phosphorylation";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)"
XP_049779927.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049785011.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_049768510.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049783950.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049777503.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049782708.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049774796.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049767824.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_049764002.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049767886.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049774721.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049764115.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049784152.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_049767014.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049778409.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049783961.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy"
XP_049776119.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049777308.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049775267.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors"
XP_049774873.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483	"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs"
XP_049780763.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049783854.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-445095	"Neutrophil degranulation";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins"
XP_049782965.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049777664.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049763277.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049782604.1	52	Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-77075;Reactome: R-HSA-167243	"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"FGFR2 alternative splicing";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery"
XP_049784251.1	6	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_049780584.1	19	Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants"
XP_049779628.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_049765199.1	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation";"Glycerolipid metabolism"
XP_049769168.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049786317.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049775261.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049766213.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049763192.1	14	MetaCyc: PWY-6538;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6596;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;Reactome: R-HSA-8851680;MetaCyc: PWY-6608;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-5497;KEGG: 00983+1.17.3.2	"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism";"Purine metabolism";"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine metabolism";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation III";"Caffeine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Drug metabolism - other enzymes"
XP_049775627.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049776835.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049784926.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049766836.1	12	MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171	"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis"
XP_049767489.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_049765166.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049765914.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049773363.1	8	Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049778207.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049778647.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049768921.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049767104.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049780058.1	5	KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_049779983.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049774746.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049780876.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049775751.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049780927.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049762595.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049783163.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049763629.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049771247.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049783680.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"mTOR signaling pathway"
XP_049784269.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049776837.1	12	MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7854;MetaCyc: PWY-5744;MetaCyc: PWY-7295;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-5749;MetaCyc: PWY-6728	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"L-arabinose degradation IV";"Pyruvate metabolism";"D-xylose degradation IV";"Itaconate degradation";"Methylaspartate cycle"
XP_049780308.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049788266.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_049781323.1	14	MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_049784543.1	8	KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905	"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis"
XP_049763121.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049766450.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884	"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX"
XP_049779537.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049769949.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049778504.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049775461.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049780676.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049782601.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_049771707.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049778562.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049766748.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049780346.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049769158.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-3371453;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-68962	"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Meiotic recombination";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Regulation of HSF1-mediated heat shock response";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex"
XP_049767757.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049781312.1	7	Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839	"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis"
XP_049774798.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049763133.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049778617.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049785852.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049776957.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049785131.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049763524.1	4	MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049762956.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049788280.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_049775849.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049785183.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049771536.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_049771077.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049781943.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_049771850.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049763830.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049763309.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049767784.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049788327.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_049774985.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049777472.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_049782379.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049776592.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049787132.1	58	MetaCyc: PWY-7094;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7007;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77350;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00380+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;Reactome: R-HSA-77310;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6946;KEGG: 00310+4.2.1.17;Reactome: R-HSA-77348;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;KEGG: 00280+4.2.1.17;Reactome: R-HSA-77288;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00640+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;KEGG: 00380+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7656;MetaCyc: PWY-5789;KEGG: 00720+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7726;MetaCyc: PWY-7401;MetaCyc: PWY-5177	"Fatty acid salvage";"Fatty acid elongation";"Butanoate metabolism";"Acyl chain remodeling of CL";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Lysine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Benzoate degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Limonene and pinene degradation";"Pyruvate fermentation to butanol II (engineered)";"Tryptophan metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Fatty acid degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Geraniol degradation";"Toluene degradation";"2-methylpropene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Lysine degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Benzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Carbon fixation pathways in prokaryotes";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Valine, leucine and isoleucine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid elongation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to hexanol (engineered)";"Propanoate metabolism";"Phenylalanine metabolism";"Caprolactam degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Tryptophan metabolism";"Fermentation to 2-methylbutanoate";"Spodoptera littoralis pheromone biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Glutaryl-coa degradation"
XP_049767512.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_049773444.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049775504.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049766499.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049776712.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049779154.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049768645.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049763548.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049779608.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049783993.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049781934.1	16	KEGG: 00640+6.2.1.4;MetaCyc: PWY-5392;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5749;MetaCyc: PWY-5538	"Propanoate metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Itaconate degradation";"Pyruvate fermentation to acetate VI"
XP_049784957.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049764859.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049777326.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049782723.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049787040.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049788358.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_049781271.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_049788060.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049775974.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049782004.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049786719.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049776552.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049784025.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049765051.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049769962.1	10	Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23	"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Other glycan degradation"
XP_049775069.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049765547.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049769916.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049784857.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049774055.1	8	MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_049768567.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock"
XP_049778559.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049783630.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049765324.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049788299.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049784021.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825	"VLDL clearance";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis"
XP_049775854.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049766678.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_049766775.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049784461.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049774747.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049784902.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_049785691.1	6	Reactome: R-HSA-446199;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273	"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis"
XP_049778336.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049765821.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049771596.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049785992.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049765049.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049787809.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049774668.1	6	MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_049765478.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049764863.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049785526.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049766583.1	7	Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625	"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049773081.1	32	Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-113418	"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"FGFR2 alternative splicing";"HIV Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex"
XP_049762445.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049781042.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049764063.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049773624.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_049779477.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049776103.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049785087.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049775063.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049764434.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049765342.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-165159	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling"
XP_049771483.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049775245.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049775762.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049780664.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049774950.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049778651.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_049771036.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_049772055.1	7	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_049775304.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins"
XP_049762916.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049768233.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781526.1	11	Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5685942	"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)"
XP_049775457.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049770672.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_049766364.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049783638.1	5	Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-6811555	"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"PI5P Regulates TP53 Acetylation"
XP_049779576.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049787534.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049768498.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis"
XP_049773179.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_049772324.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049774033.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1"
XP_049773746.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049773778.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049777841.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049777001.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131	"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR"
XP_049784050.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3"
XP_049788268.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049787608.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049773791.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049776183.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049773140.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049767243.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049776970.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049781648.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049765156.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049773054.1	5	KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074	"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Mevalonate degradation"
XP_049771976.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049782638.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049783478.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049787361.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049768246.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049775084.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049765043.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_049783866.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049779749.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049767759.1	21	Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-1236974;Reactome: R-HSA-5357905;Reactome: R-HSA-975144;Reactome: R-HSA-937041;Reactome: R-HSA-202424;Reactome: R-HSA-5603029;Reactome: R-HSA-933543;Reactome: R-HSA-933542;Reactome: R-HSA-5684264;Reactome: R-HSA-5603027;Reactome: R-HSA-1810476;Reactome: R-HSA-937039;Reactome: R-HSA-168927;Reactome: R-HSA-5602636;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091	"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"ER-Phagosome pathway";"Regulation of TNFR1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IKK complex recruitment mediated by RIP1";"Downstream TCR signaling";"IkBA variant leads to EDA-ID";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TRAF6 mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"RIP-mediated NFkB activation via ZBP1";"IRAK1 recruits IKK complex";"TICAM1, RIP1-mediated IKK complex recruitment";"IKBKB deficiency causes SCID";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells"
XP_049769322.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049776679.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)"
XP_049786493.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049779526.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049769789.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541	"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Neddylation";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway"
XP_049776831.1	12	KEGG: 00660+4.1.3.25;MetaCyc: PWY-7118;MetaCyc: PWY-6969;MetaCyc: PWY-7854;MetaCyc: PWY-5744;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7295;KEGG: 00620+2.3.3.9;MetaCyc: PWY-6728;MetaCyc: PWY-5749	"C5-Branched dibasic acid metabolism";"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"L-arabinose degradation IV";"Pyruvate metabolism";"Methylaspartate cycle";"Itaconate degradation"
XP_049785614.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_049774192.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049782198.1	6	Reactome: R-HSA-9640463;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"Wax biosynthesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_049765684.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition"
XP_049773871.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049777062.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049763191.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_049777987.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_049778572.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049763696.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049763713.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-5685939	"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)"
XP_049783110.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049777174.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049764091.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Regulation of PTEN stability and activity"
XP_049765771.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049778413.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-2559586	"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence"
XP_049773943.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049763522.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049767790.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049773752.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049782610.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049773839.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049765788.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049773066.1	6	MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-6908;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2	"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine metabolism"
XP_049776928.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049779362.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049777646.1	18	KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115	"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049774405.1	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049765633.1	6	MetaCyc: PWY-6367;MetaCyc: PWY-6580;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_049769570.1	5	KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201	"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations I"
XP_049770234.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_049783992.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049783853.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_049774329.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049776547.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049767379.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049769201.1	9	Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1	"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism"
XP_049784515.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049775959.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049775788.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049785954.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_049774054.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049777371.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783424.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_049783557.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049785245.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049785423.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049781559.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049770335.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_049783705.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-70221	"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen degradation II";"Starch degradation II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)"
XP_049785771.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049773835.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049775081.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
XP_049787169.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-381676	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049777542.1	29	Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression"
XP_049780208.1	8	Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Signaling by Hippo";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_049776548.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049778000.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049782833.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049780929.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049765923.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049778960.1	12	Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;MetaCyc: PWY-6121;MetaCyc: PWY-6277	"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_049764521.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_049776000.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049787044.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049781847.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049763314.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049780506.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425	"Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049784092.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_049787547.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049770924.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049784956.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773229.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049769107.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049787104.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049785404.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049787985.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049777042.1	16	Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828	"LDL clearance";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis"
XP_049783833.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049773747.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049769778.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-202040	"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G-protein activation"
XP_049777038.1	11	MetaCyc: PWY-5381;MetaCyc: PWY-6608;MetaCyc: PWY-6607;MetaCyc: PWY-6606;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5695	"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation"
XP_049764733.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049765135.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049782282.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049780004.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049769632.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049774337.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049776772.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049773443.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_049774666.1	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049766808.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049781632.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism"
XP_049776392.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_049788448.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049783769.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049780995.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049774983.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049785383.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049768248.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049782980.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049780090.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049780672.1	14	KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4	"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Synthesis of PE";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism"
XP_049783246.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049780784.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_049780362.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049769854.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049764969.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_049777057.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785511.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049774420.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049773079.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974	"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway"
XP_049786809.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_049785597.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049783042.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661	"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation"
XP_049772577.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049763843.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049775068.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049776372.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049762700.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_049778273.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-881907;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events"
XP_049781505.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049776785.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049770014.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-3214847	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"HATs acetylate histones"
XP_049762697.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER"
XP_049778119.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_049773658.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_049783136.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049777052.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049785674.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049765690.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_049778912.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_049774710.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049780507.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_049784088.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049785497.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049777669.1	24	Reactome: R-HSA-165158;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-5625740	"Activation of AKT2";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Integrin signaling";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway";"RSK activation";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"RHO GTPases activate PKNs"
XP_049762905.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049784936.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_049762543.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049781812.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049773831.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049782247.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_049787030.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049763673.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049773817.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049785024.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049766747.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049788415.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049774450.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049787335.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049780376.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049766750.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049775603.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049766264.1	6	Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3	"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism"
XP_049771155.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049784865.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_049787014.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408	"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049763826.1	8	KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-6556;Reactome: R-HSA-73614;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I"
XP_049773754.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049768190.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049781039.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049764060.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049774144.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-9630221	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing"
XP_049776853.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049779996.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049775373.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049766204.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049766512.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049778008.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_049782010.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_049781791.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049778799.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049784378.1	8	MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27	"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism"
XP_049769082.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466	"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis"
XP_049770387.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049764828.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049766578.1	7	Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625	"Synthesis of PI";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049763249.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_049775920.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049784643.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049788014.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049787471.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049767601.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049787775.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049764206.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049781045.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049766754.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049763372.1	10	Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-202424	"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling"
XP_049785745.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049780756.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049786996.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049783895.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_049767062.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049786950.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049778373.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049781066.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_049784396.1	12	MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132	"Cis-genanyl-coa degradation";"Methane metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis"
XP_049762596.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049786460.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049783214.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049772447.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049775973.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049786693.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049777527.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049764324.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049777632.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049786985.1	10	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916	"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation"
XP_049773036.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049786564.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_049784210.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049780787.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049775966.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049763835.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049766284.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049762236.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_049772995.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049781822.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411	"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)"
XP_049772487.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049774247.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049785334.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049781404.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049777138.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049779373.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049778337.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049776684.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735	"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis"
XP_049766924.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049773921.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_049774529.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049766587.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_049775120.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049786109.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049765014.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_049779294.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049770806.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049775260.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049774304.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049784593.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049766526.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049776780.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049780888.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_049786933.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049777831.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538	"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA"
XP_049768162.1	12	Reactome: R-HSA-174362;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25	"Transport and synthesis of PAPS";"Sulfite oxidation III";"Purine metabolism";"Selenocompound metabolism";"Monobactam biosynthesis";"Selenate reduction";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfate activation for sulfonation";"Purine metabolism"
XP_049776640.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648	"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049788133.1	13	KEGG: 00230+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184	"Purine metabolism";"Purine catabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049767744.1	7	MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7818	"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_049787090.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049767186.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_049779347.1	10	Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012	"PERK regulates gene expression";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049774362.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins"
XP_049763155.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_049768985.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7417	"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049787235.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
XP_049764877.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-168333	"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049774694.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049762257.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781030.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757	"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation"
XP_049777152.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049787533.1	11	KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_049780119.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049770874.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049776908.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049781305.1	12	MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_049773597.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974	"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Neddylation";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"ER-Phagosome pathway"
XP_049773988.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_049778081.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049765073.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049765229.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049782434.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049772933.1	8	Reactome: R-HSA-4608870;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-4641263;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-4086398;Reactome: R-HSA-373080	"Asymmetric localization of PCP proteins";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Ca2+ pathway";"Class B/2 (Secretin family receptors)"
XP_049782119.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049785813.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049767024.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049763223.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049786679.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"MET activates PTK2 signaling"
XP_049777071.1	7	MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-5698	"UMP biosynthesis II";"Pyrimidine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"Allantoin degradation to ureidoglycolate II (ammonia producing)"
XP_049774531.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049774448.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049776782.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049773452.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049780734.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049763516.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_049780951.1	24	Reactome: R-HSA-5610785;Reactome: R-HSA-442720;Reactome: R-HSA-5687128;Reactome: R-HSA-422356;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-111931;Reactome: R-HSA-381676;Reactome: R-HSA-5621575;Reactome: R-HSA-392517;Reactome: R-HSA-4420097;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-8963896;Reactome: R-HSA-163358;Reactome: R-HSA-8853659;Reactome: R-HSA-5610783;KEGG: 04150+2.7.11.11;Reactome: R-HSA-9010642;Reactome: R-HSA-163560;Reactome: R-HSA-5610780;Reactome: R-HSA-9634600;Reactome: R-HSA-5610787	"GLI3 is processed to GLI3R by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"MAPK6/MAPK4 signaling";"Regulation of insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA-mediated phosphorylation of CREB";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CD209 (DC-SIGN) signaling";"Rap1 signalling";"VEGFA-VEGFR2 Pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"HDL assembly";"PKA-mediated phosphorylation of key metabolic factors";"RET signaling";"Degradation of GLI2 by the proteasome";"mTOR signaling pathway";"ROBO receptors bind AKAP5";"Triglyceride catabolism";"Degradation of GLI1 by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Hedgehog 'off' state"
XP_049784986.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049766479.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049784876.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049767785.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049766779.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049780926.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
YP_010401622.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049775070.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049785028.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049764018.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_049787099.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049767005.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049770089.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network"
XP_049781612.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049769209.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049783139.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049776630.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049766064.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049770884.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049764073.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049787535.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049788416.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049788054.1	4	Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049781223.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049775122.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049769085.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049775292.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049787463.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049762682.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049762734.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_049783254.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049780613.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049788048.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049763139.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049763318.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049772171.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049768748.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049771430.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049784546.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049783728.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049785333.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049764852.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_049766966.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049765515.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049783713.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_049763829.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049775826.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049770117.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049779035.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_049776165.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025	"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation"
XP_049783237.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
XP_049778401.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049784498.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049779638.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049776156.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_049767058.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049763452.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_049769274.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049781607.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049764919.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049773990.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049785781.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801	"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049781369.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_049781343.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049775095.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049778384.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_049787059.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049773365.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049768494.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049782874.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049762454.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049763453.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_049775785.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049782405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049768857.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049779075.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_049767362.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049776786.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049777526.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049782116.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049762788.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049786691.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049778710.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049774466.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049778082.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049775464.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049779867.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049778395.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049777017.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049779328.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery"
XP_049776142.1	21	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7219;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6	"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_049773979.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049780675.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049788030.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049774140.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049783923.1	6	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Biotin transport and metabolism";"Lipoic acid metabolism"
XP_049765120.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-5099900	"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4"
XP_049765891.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049779610.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049767248.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049784759.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_049767212.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339	"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane"
XP_049774075.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines"
XP_049785364.1	6	Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-6309;MetaCyc: PWY-7717;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9	"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism"
XP_049767139.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049771220.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049773636.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049781348.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049776158.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade"
XP_049762305.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049763227.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049781584.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049779392.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049786068.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049781092.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049770837.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049776244.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049765626.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_049777660.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049774564.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049770293.1	7	Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049787161.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049779011.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049788271.1	4	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis"
XP_049779463.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049766385.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049781491.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049764150.1	18	MetaCyc: PWY-5046;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;Reactome: R-HSA-6783984;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00260+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00310+1.8.1.4	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Glycine degradation";"Propanoate metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Glycine, serine and threonine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Lysine degradation"
XP_049785970.1	4	Reactome: R-HSA-8964011;Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-3359462	"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_049764357.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_049767917.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049768630.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049767070.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049770827.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle"
XP_049762735.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049788056.1	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_049774474.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049763479.1	5	Reactome: R-HSA-4793954;MetaCyc: PWY-7918;Reactome: R-HSA-532668;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106	"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis"
XP_049762530.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049773053.1	5	KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4	"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism"
XP_049778947.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection"
XP_049783466.1	4	MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049767137.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049782209.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049780596.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-877300	"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Interferon gamma signaling"
XP_049764774.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049769040.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049786668.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049774471.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049777474.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_049787175.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_049786820.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049784588.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049764975.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049784026.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049786451.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049774079.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049783481.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049770578.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049774283.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049786911.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049766524.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049787308.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Stachyose degradation";"Galactose catabolism"
XP_049780595.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692	"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Regulation of MECP2 expression and activity"
XP_049774237.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049778148.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049763501.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049785363.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-7717;MetaCyc: PWY-7765	"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_049775083.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049786998.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-381033;Reactome: R-HSA-8957275	"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation"
XP_049786541.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049776189.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049786768.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049776799.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049788183.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049763215.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-350562	"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)"
XP_049783861.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition"
XP_049767063.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049777727.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049779279.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049785900.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049776594.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane"
XP_049773109.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_049769645.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-450408	"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049783095.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049770941.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049776898.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049785312.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049763013.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049763363.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761	"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049763012.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049786863.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049775318.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049766905.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049781216.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049779069.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_049784803.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049787100.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049774923.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049774296.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049768955.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049781034.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049775045.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049783044.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049776818.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049788295.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049769733.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049779902.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049785033.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049785319.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049769635.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049782306.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049786701.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression"
XP_049763157.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049775952.1	9	MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049779369.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049777964.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049781602.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049771599.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049777771.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049764936.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049778072.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049783006.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049770687.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049786051.1	6	Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25	"MPS VII - Sly syndrome";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049773535.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049778499.1	10	Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"mTOR signaling pathway"
XP_049784216.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049762776.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_049770946.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_049780497.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632	"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis"
XP_049765273.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049766065.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049783106.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049777365.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049773716.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049767461.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_049767106.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049784849.1	20	MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6	"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism"
XP_049784946.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049774961.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167287	"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery"
XP_049777882.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_049765121.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828	"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis"
XP_049777996.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049774193.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049781935.1	16	MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5392	"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Itaconate degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Reductive TCA cycle II"
XP_049763173.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049771960.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049777088.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049763658.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049778845.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination"
XP_049786745.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-525793	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Myogenesis"
XP_049784577.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049782985.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049780799.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049770524.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049786752.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation"
XP_049773861.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_049768939.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049762486.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling"
XP_049785517.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049783367.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state"
XP_049772084.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049784923.1	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
XP_049776118.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049787142.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049765184.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049767253.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"