Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_049812389.1	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049810795.1	7	Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-3561	"Synthesis of PG";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Choline biosynthesis III"
XP_049810000.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811558.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049797556.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-111465	"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins"
XP_049810325.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049794205.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807227.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049816470.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049809847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049804487.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049808382.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049814924.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049812051.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638	"p38MAPK events";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway"
XP_049788636.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049812992.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049813349.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049811559.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049814835.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049796244.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling"
XP_049793104.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049815670.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049808098.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049813209.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049789449.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_049814946.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-606279	"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049788907.1	4	Reactome: R-HSA-3232142;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-983168	"SUMOylation of ubiquitinylation proteins";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049804706.1	5	MetaCyc: PWY-7766;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-5531	"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_049813031.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049799778.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804600.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049808629.1	30	Reactome: R-HSA-2122947;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-400253;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-187577	"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Circadian Clock";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21"
XP_049811075.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049803141.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049806580.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046	"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Chylomicron remodeling";"Platelet sensitization by LDL";"LDL remodeling";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"LDL clearance";"Chylomicron clearance";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"VLDL clearance"
XP_049810002.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806305.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049809674.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049812662.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049813231.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049807914.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_049802817.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049805966.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049816314.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins"
XP_049792758.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_049798349.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049806635.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049801719.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049789678.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049791052.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049809756.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049792951.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110373	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
XP_049790993.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049792175.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049795202.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_049788898.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049795577.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049795951.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049799164.1	5	Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049794508.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049799430.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049801512.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049792904.1	7	MetaCyc: PWY-7625;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11	"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_049789958.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049815704.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049794101.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049811449.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049804021.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049793841.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_049790372.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049806568.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049812702.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049794405.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049808557.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049796775.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049810819.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049809353.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049803525.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049791185.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049796957.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049803234.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-5673001	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade"
XP_049816517.1	5	MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_049810465.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049804273.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049810468.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049812177.1	8	MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049794062.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049804869.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049814595.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049801392.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049803472.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049793110.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049816766.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049792706.1	57	Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128	"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling"
XP_049792213.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049808852.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049791764.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_049788657.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049793105.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049800998.1	4	KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_049802577.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049793151.1	21	Reactome: R-HSA-5603029;Reactome: R-HSA-168638;Reactome: R-HSA-937039;Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-168927;Reactome: R-HSA-1810476;Reactome: R-HSA-5603027;Reactome: R-HSA-1236974;Reactome: R-HSA-937041;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-5684264;Reactome: R-HSA-5357905;Reactome: R-HSA-5602636;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-933543;Reactome: R-HSA-933542;Reactome: R-HSA-1169091	"IkBA variant leads to EDA-ID";"NOD1/2 Signaling Pathway";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"RIP-mediated NFkB activation via ZBP1";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"ER-Phagosome pathway";"IKK complex recruitment mediated by RIP1";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of TNFR1 signaling";"IKBKB deficiency causes SCID";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TRAF6 mediated NF-kB activation";"Activation of NF-kappaB in B cells"
XP_049816746.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049802105.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049805093.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049799449.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_049805560.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049806012.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_049805635.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049793237.1	10	MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-1042	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)"
XP_049795361.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-3371511;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5696397	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"HSF1 activation";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049805157.1	7	MetaCyc: PWY-6614;Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-3841	"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)"
XP_049803948.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049813295.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049790086.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049810419.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5578749	"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs"
XP_049813632.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049811517.1	52	Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-73780;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Chain Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049801282.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_049797109.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_049796251.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049810184.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049795452.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049789597.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049806068.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049791222.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049815920.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049808242.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049797575.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_049792656.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049808466.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_049810421.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083	"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions"
XP_049802114.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_049801676.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049806552.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049811887.1	6	Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-5651	"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
XP_049791728.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792422.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_049795807.1	29	Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-3371453;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-3371511;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Regulation of HSF1-mediated heat shock response";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"HSF1 activation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Dual incision in TC-NER"
XP_049805926.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049793730.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049813021.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791394.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6	"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049789008.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049814336.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_049810644.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049789604.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049793141.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049814138.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049815736.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049815684.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049788568.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_049809182.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049813460.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049791296.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049807016.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049803986.1	10	MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-4041	"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle"
XP_049804373.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049788807.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_049791195.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049810665.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
YP_010401644.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049793486.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049801661.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049790881.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049807305.1	14	MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II"
XP_049793824.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049807502.1	9	KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842	"Drug metabolism - other enzymes";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II"
XP_049808414.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_049804104.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049812078.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049792263.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049801805.1	1	Reactome: R-HSA-8963684	"Tyrosine catabolism"
XP_049795953.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049788802.1	14	Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257	"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion"
XP_049791801.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049807754.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049793111.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049798333.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049814291.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049809266.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049792861.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5467340	"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"RAF activation";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex"
XP_049802246.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-381340	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation"
XP_049816795.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049792487.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049799367.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049790815.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049790661.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049790963.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-432720	"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis"
XP_049810367.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049798844.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049805636.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_049797113.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049792639.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049812864.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049809716.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Alanine racemization"
XP_049794694.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049804973.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049807616.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049806447.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_049809641.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815009.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049801235.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049795913.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049803847.1	17	KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;MetaCyc: PWY-6728;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Methane metabolism";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049810069.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049796211.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049808210.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049811833.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049803471.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049800563.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049799674.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049811990.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049790978.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-186763	"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Downstream signal transduction"
XP_049807428.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_049816706.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049804456.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091	"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells"
XP_049810929.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049800832.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049799116.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049804541.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs"
XP_049812848.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049793293.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049804556.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049815726.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_049791587.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049804878.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049812466.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049802904.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049812999.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049812743.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049797913.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049798996.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange"
XP_049814580.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049799077.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049809362.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049806587.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049811917.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789664.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049807770.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049814504.1	5	MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049803398.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_049793002.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade"
XP_049808268.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049810005.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793122.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049814505.1	5	MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049814253.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049815738.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801155.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049801738.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049815728.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_049814174.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049808796.1	26	Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"PPARA activates gene expression";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Attenuation phase";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049813018.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_049804889.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049813095.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049801568.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049810365.1	4	Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-499943	"Neutrophil degranulation";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates"
XP_049790837.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049811499.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049807447.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049805624.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Nephrin family interactions";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade"
XP_049811484.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049811396.1	4	MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049799246.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049806748.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049799845.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049802315.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_049797111.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-429947	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA"
XP_049815059.1	18	MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383	"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Sulfolactate degradation III";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049795242.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis"
XP_049795405.1	28	Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-3371453;Reactome: R-HSA-3371511;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110320	"G2/M DNA damage checkpoint";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of HSF1-mediated heat shock response";"HSF1 activation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH"
XP_049806715.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049813669.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049813536.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049802693.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815745.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049799079.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049814934.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_049815956.1	13	MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7736	"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis"
XP_049791506.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049800682.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049806183.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049795731.1	9	Reactome: R-HSA-3371599;MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263	"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Gluconeogenesis"
XP_049790469.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049803403.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049806449.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049789882.1	10	MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2	"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism"
XP_049788695.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049810709.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_049794040.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616	"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049800766.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049812883.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049788553.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049801367.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049803183.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors"
XP_049810208.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805899.1	19	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-163765;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049789169.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049815652.1	58	KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-6583;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-7216;MetaCyc: PWY-7778;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00360+4.2.1.17;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-5109;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00280+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-6945;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00362+4.2.1.17;KEGG: 00310+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77346;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00650+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5136;Reactome: R-HSA-1482798;MetaCyc: PWY-7779;MetaCyc: PWY-7726;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;MetaCyc: PWY-6863;MetaCyc: PWY-5138;Reactome: R-HSA-77288;MetaCyc: PWY-7401;MetaCyc: PWY-7656;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00640+4.2.1.17	"Geraniol degradation";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"Caprolactam degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"beta-Alanine metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"2-methylpropene degradation";"Androstenedione degradation";"Limonene and pinene degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Phenylalanine metabolism";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Toluene degradation";"Tryptophan metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Carbon fixation pathways in prokaryotes";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Benzoate degradation";"Lysine degradation";"Fatty acid elongation";"Caprolactam degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation II (plant peroxisome)";"Acyl chain remodeling of CL";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Spodoptera littoralis pheromone biosynthesis";"Benzoate degradation";"Fatty acid salvage";"Propanoate metabolism"
XP_049788508.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_049812661.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049810334.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6364;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049803409.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049809601.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049788977.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049791132.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049796843.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049807592.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049815693.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049805470.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049805541.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-445144	"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Synthesis of PC";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Signal transduction by L1"
XP_049788990.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049794833.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049802952.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049792119.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049791571.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049813533.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049795787.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049806593.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695	"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation"
XP_049792936.1	14	Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-1632852;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Macroautophagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049815499.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049815662.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_049811557.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_049793438.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049814018.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_049791669.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049793116.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049810298.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049814287.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049799572.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049790129.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049808261.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_049792791.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049813546.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-437239	"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recycling pathway of L1"
XP_049790196.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049815164.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049812424.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049802321.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049808772.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049807503.1	9	KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061	"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I"
XP_049812819.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049814456.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049807252.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling"
XP_049806679.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049799952.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-211733	"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_049801694.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049799987.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling"
XP_049815050.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049810226.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-156581	"Ub-specific processing proteases";"Methylation"
XP_049790636.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241	"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import"
XP_049790725.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_049800741.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049813884.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049789653.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049803490.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049812650.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049811700.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_049800603.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049795136.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049815768.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049793183.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049802898.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049799399.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808593.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049816247.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049796863.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049788897.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049804114.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_049800996.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049793587.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049814502.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_049791425.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049802685.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049813742.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_049806150.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049807945.1	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049801048.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_049795867.1	56	Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258	"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Degradation of DVL"
XP_049792889.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049799693.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049813056.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049792520.1	6	Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204	"Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol"
XP_049811616.1	11	Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-68952	"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"DNA replication initiation"
XP_049815546.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049811493.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049801042.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049795250.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049794976.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049795398.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049789794.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049806186.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_049810498.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049800922.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_049812125.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049802479.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_049794797.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049809102.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049804567.1	6	Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_049811769.1	5	MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781	"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)"
XP_049812943.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049793113.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049797973.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049804691.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_049812281.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-9609690	"Kinesins";"Recycling pathway of L1";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"HCMV Early Events"
XP_049807138.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049790035.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_049807860.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_049795450.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049805727.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049804715.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049806514.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_049791903.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049803528.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049816844.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049811970.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049789218.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049802477.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049807469.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049809700.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049793708.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_049812055.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049791800.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049808833.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812368.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049795742.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049791083.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049803750.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049803947.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049814378.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049801537.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200	"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049814824.1	13	MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049815942.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049810343.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049805548.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049790825.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049797968.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_049792233.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049793212.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807634.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis"
XP_049789611.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049794628.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049807715.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049797102.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-450408	"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049808363.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800528.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049801677.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049798308.1	9	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection"
XP_049795446.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_049788993.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049802312.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049805529.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I"
XP_049797104.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049802387.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049802945.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049791883.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049813024.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049788736.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049812654.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-177929;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-75893;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-5362798;Reactome: R-HSA-2894862	"Nuclear signaling by ERBB4";"Signaling by EGFR";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"TNF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Growth hormone receptor signaling";"Collagen degradation";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049801406.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049801715.1	10	Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942	"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)"
XP_049805988.1	16	KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5913;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_049810714.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049800276.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049798941.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049793037.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_049797628.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049805137.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049815627.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport"
XP_049801958.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049802043.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049795353.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122	"Synthesis of PC";"Signal transduction by L1";"Neutrophil degranulation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049804983.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049802394.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049814101.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049802710.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049810100.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport"
XP_049808773.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814318.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049805756.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049811505.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049802640.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism"
XP_049809741.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049810596.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis"
XP_049796615.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670	"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway"
XP_049795538.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049802605.1	4	Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204	"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_049805459.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049809634.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049812207.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049788909.1	4	Reactome: R-HSA-3232142;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"SUMOylation of ubiquitinylation proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049803481.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049793142.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049801049.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049811886.1	6	MetaCyc: PWY-5651;MetaCyc: PWY-7765;MetaCyc: PWY-6309;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;Reactome: R-HSA-71240	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism"
XP_049804342.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049799374.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049793140.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049805726.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049804751.1	11	Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"p38MAPK events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049795535.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism"
XP_049790812.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049793554.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842	"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"HDMs demethylate histones"
XP_049797908.1	29	Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-3371453;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110320	"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of HSF1-mediated heat shock response";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH"
XP_049804455.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091	"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells"
XP_049801178.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049815114.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049810664.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049801016.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049803482.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049801631.1	6	KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403	"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)"
XP_049802427.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049805772.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049807966.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667	"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I"
XP_049789761.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049792535.1	6	KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation"
XP_049795804.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-110312;Reactome: R-HSA-3371511;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310	"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by REV1";"HSF1 activation";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway"
XP_049798290.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049810627.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049809134.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049790982.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049806130.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049810722.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049807170.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049790960.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-196025	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions"
XP_049807850.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808783.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-210744	"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_049788527.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049800365.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049804082.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049814778.1	34	Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-9639288;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-191859	"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Amino acids regulate mTORC1";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly"
XP_049795191.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049788750.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049816588.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049806116.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049805757.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_049797999.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events"
XP_049793152.1	21	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-5603029;Reactome: R-HSA-168638;Reactome: R-HSA-168927;Reactome: R-HSA-9020702;Reactome: R-HSA-1810476;Reactome: R-HSA-5603027;Reactome: R-HSA-1236974;Reactome: R-HSA-937041;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-5357956;Reactome: R-HSA-5357905;Reactome: R-HSA-5607764;Reactome: R-HSA-5602636;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-933542;Reactome: R-HSA-933543;Reactome: R-HSA-1169091	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"IkBA variant leads to EDA-ID";"NOD1/2 Signaling Pathway";"TICAM1, RIP1-mediated IKK complex recruitment";"Interleukin-1 signaling";"RIP-mediated NFkB activation via ZBP1";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"ER-Phagosome pathway";"IKK complex recruitment mediated by RIP1";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling";"CLEC7A (Dectin-1) signaling";"IKBKB deficiency causes SCID";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"TRAF6 mediated NF-kB activation";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"Activation of NF-kappaB in B cells"
XP_049812498.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_049813625.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049815661.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7659;MetaCyc: PWY-7736;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7182	"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I"
XP_049815505.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049807061.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049799704.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049801390.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049805524.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049813393.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049816826.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049812606.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_049806099.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049809810.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049790114.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049803389.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049790637.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-6920	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)"
XP_049806611.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-5668599;Reactome: R-HSA-1236973;Reactome: R-HSA-4420097;Reactome: R-HSA-3299685	"ROS and RNS production in phagocytes";"RHO GTPases Activate NADPH Oxidases";"Cross-presentation of particulate exogenous antigens (phagosomes)";"VEGFA-VEGFR2 Pathway";"Detoxification of Reactive Oxygen Species"
XP_049801726.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049788738.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049803392.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)"
XP_049800564.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049792960.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049797669.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049788651.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049805835.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049801955.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049813459.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_049815796.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049810400.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049808624.1	13	MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1	"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism"
XP_049802255.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049815491.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049805601.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049804605.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049806919.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049816055.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049812492.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049799885.1	14	MetaCyc: PWY-7409;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049793403.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049801419.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049794109.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049799442.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14	"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_049790017.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049816767.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049791223.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049808837.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808951.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814699.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049792825.1	13	Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-389357	"Macroautophagy";"PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"mTOR signalling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling"
XP_049795708.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049810766.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049791104.1	14	KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5104;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5101;Reactome: R-HSA-70895;MetaCyc: PWY-5076;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103	"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine degradation II";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"L-leucine degradation III";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III"
XP_049814611.1	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_049798287.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695	"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation"
XP_049815949.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049808811.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805514.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_049807681.1	6	KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049789161.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049794710.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_049809272.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049804276.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815138.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174184	"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Neddylation";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_049788824.1	6	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_049791386.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049793851.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_049815919.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049807852.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049789341.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049815180.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049788822.1	6	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_049809133.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049794379.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049808492.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049790903.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049808432.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049806601.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049806640.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049790976.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_049793624.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049805760.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049797670.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049790056.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049791082.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049795352.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756	"Signal transduction by L1";"Neutrophil degranulation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation"
XP_049816615.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049790995.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049800817.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049812097.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049805710.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049790802.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_049799080.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049789654.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049816368.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049788773.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_049795230.1	27	Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-4641262;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358749;KEGG: 05165+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-8939902;Reactome: R-HSA-5250924;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5610785;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75815;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5358752;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5358747	"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human cytomegalovirus infection";"S37 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Regulation of RUNX2 expression and activity";"B-WICH complex positively regulates rRNA expression";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"GLI3 is processed to GLI3R by the proteasome";"Human immunodeficiency virus 1 infection";"Ubiquitin-dependent degradation of Cyclin D";"mTOR signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"T41 mutants of beta-catenin aren't phosphorylated";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"S33 mutants of beta-catenin aren't phosphorylated"
XP_049814470.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049803160.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049792108.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049801437.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049805676.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049802474.1	5	Reactome: R-HSA-446388;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049793971.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801198.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049807566.1	4	KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;Reactome: R-HSA-189483;MetaCyc: PWY-5874	"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation";"Heme degradation I"
XP_049810591.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_049803149.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049802503.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_049805225.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049801768.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_049808652.1	13	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049815862.1	3	MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3	"Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism"
XP_049790458.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_049803960.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001	"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_049805848.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049804389.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049797494.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804628.1	19	Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041	"Retinoid metabolism and transport";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class H Receptors";"Chylomicron clearance";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Chylomicron remodeling";"LDL remodeling"
XP_049793799.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049802141.1	7	KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7586	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_049796388.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049806506.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049793487.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049797648.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_049807383.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_049809909.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-174178	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Neddylation";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049802895.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049808335.1	9	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049810758.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049794058.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049800864.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_049802041.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049813474.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049808851.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800361.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811919.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793472.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
YP_010401633.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049789318.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recycling pathway of L1";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly"
XP_049803596.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049811064.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049793308.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049807087.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756;Reactome: R-HSA-936440	"ISG15 antiviral mechanism";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling"
XP_049813195.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends"
XP_049804489.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049811300.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049795354.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122	"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Neutrophil degranulation";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049814503.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_049815450.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804116.1	33	MetaCyc: PWY-5082;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-5480;MetaCyc: PWY-7013;MetaCyc: PWY-7118;MetaCyc: PWY-5751;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5076;Reactome: R-HSA-71384;KEGG: 00982+1.1.1.1;MetaCyc: PWY-1801;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6587;MetaCyc: PWY-3162;MetaCyc: PWY-6802;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-6333;KEGG: 00071+1.1.1.1;KEGG: 00830+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-7111;MetaCyc: PWY-6871;MetaCyc: PWY-6342;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-6313;KEGG: 00626+1.1.1.1	"L-methionine degradation III";"Chloroalkane and chloroalkene degradation";"Protein S-nitrosylation and denitrosylation";"Pyruvate fermentation to ethanol I";"(S)-propane-1,2-diol degradation";"Chitin degradation to ethanol";"Phenylethanol biosynthesis";"Methane metabolism";"L-leucine degradation III";"Ethanol oxidation";"Drug metabolism - cytochrome P450";"Formaldehyde oxidation II (glutathione-dependent)";"Metabolism of xenobiotics by cytochrome P450";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol III";"L-tryptophan degradation V (side chain pathway)";"Salidroside biosynthesis";"Glycine, serine and threonine metabolism";"L-isoleucine degradation II";"Tyrosine metabolism";"Pyruvate fermentation to ethanol II";"Acetaldehyde biosynthesis I";"Fatty acid degradation";"Retinol metabolism";"Glycolysis / Gluconeogenesis";"L-valine degradation II";"Pyruvate fermentation to isobutanol (engineered)";"3-methylbutanol biosynthesis (engineered)";"Noradrenaline and adrenaline degradation";"alpha-Linolenic acid metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"Naphthalene degradation"
XP_049816753.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049809410.1	11	Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrogen metabolism"
XP_049793091.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049809630.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049807262.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_049814493.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Long-term potentiation"
XP_049797960.1	1	Reactome: R-HSA-156581	"Methylation"
XP_049808421.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_049793339.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049788556.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822	"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_049801592.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049790423.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-8849471;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFA-VEGFR2 Pathway"
XP_049808377.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049815817.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049807674.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_049807269.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049799244.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049808302.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049809846.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049789635.1	8	MetaCyc: PWY-66;MetaCyc: PWY-5739;MetaCyc: PWY-7573;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740	"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis"
XP_049808430.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049790494.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049809749.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049803032.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049788989.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049806511.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049795672.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049814840.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049794339.1	7	KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16	"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_049810342.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049798014.1	5	Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532	"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)"
XP_049802072.1	9	Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTORC1-mediated signalling";"mTOR signalling"
XP_049802512.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049810355.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange"
XP_049802739.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049810611.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049802960.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049802907.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_049794457.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049798021.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049809628.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049800599.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049796067.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049792360.1	13	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049795013.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049804374.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049792600.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-430039	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_049793533.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049789166.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049802642.1	4	KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817	"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_049799099.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_049793137.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805715.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049800830.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049815504.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049800576.1	17	Reactome: R-HSA-69656;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-69202;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585;Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-1538133;Reactome: R-HSA-111448;Reactome: R-HSA-139915;Reactome: R-HSA-2173796;Reactome: R-HSA-8953750	"Cyclin A:Cdk2-associated events at S phase entry";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"Cyclin E associated events during G1/S transition";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"G0 and Early G1";"Activation of NOXA and translocation to mitochondria";"Activation of PUMA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6"
XP_049791784.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049815117.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049794863.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049789990.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049789286.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049802790.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049805952.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049799389.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_049800803.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049803532.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_049802901.1	6	Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795	"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling"
XP_049795111.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049805319.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_049800445.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049794988.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049801548.1	3	Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269	"Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_049790831.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377	"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins"
XP_049793940.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049808420.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
YP_010401635.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049801223.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049802707.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049811699.1	6	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"
XP_049815212.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049797840.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049809122.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049811194.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049809127.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049794245.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049794232.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049808824.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813524.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049789026.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049816057.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049802336.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-168179;Reactome: R-HSA-5686938;Reactome: R-HSA-166058;Reactome: R-HSA-5602498;Reactome: R-HSA-5603041;Reactome: R-HSA-1236974;Reactome: R-HSA-9637628;Reactome: R-HSA-1461957;Reactome: R-HSA-168188	"Neutrophil degranulation";"Toll Like Receptor TLR1:TLR2 Cascade";"Regulation of TLR by endogenous ligand";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR2/4)";"ER-Phagosome pathway";"Modulation by Mtb of host immune system";"Beta defensins";"Toll Like Receptor TLR6:TLR2 Cascade"
XP_049789702.1	6	Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001	"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade"
XP_049802653.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049811401.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049799120.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049797485.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_049791948.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049800905.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049810058.1	5	MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_049808258.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049811110.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049813105.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049809468.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805854.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049790585.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049805389.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049811249.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049811344.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049806944.1	20	Reactome: R-HSA-380320;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7227;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-499943	"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates"
XP_049794075.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049797801.1	2	MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis"
XP_049814850.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049794853.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049793937.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808916.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Neutrophil degranulation";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_049812988.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363	"Streptomycin biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_049806152.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049808369.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800802.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_049794172.1	7	MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7886	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_049807897.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049794083.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenoamino acid metabolism"
XP_049811342.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049800160.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049802801.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
YP_010401643.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049801146.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049789860.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049808769.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816796.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049804969.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049802465.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049797475.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826	"Signaling by EGFR";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049797596.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049795725.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049801731.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049788761.1	10	KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_049814849.1	21	MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7210;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6	"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes"
XP_049801076.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049812652.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049812185.1	37	Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-9639288;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-204005;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-983170;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-2132295;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-5619107	"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Separation of Sister Chromatids";"COPII-mediated vesicle transport";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"MHC class II antigen presentation";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_049800367.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815257.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_049811457.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049803878.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049792938.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049808364.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049790904.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049814003.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049815857.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049792190.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049791191.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049801651.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049802393.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049816117.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049796152.1	11	Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-210990;Reactome: R-HSA-877312;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-391160;Reactome: R-HSA-909733;Reactome: R-HSA-388841;Reactome: R-HSA-114604	"PD-1 signaling";"Platelet sensitization by LDL";"PECAM1 interactions";"Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"Interleukin-37 signaling";"Signal regulatory protein family interactions";"Interferon alpha/beta signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade"
XP_049808759.1	11	MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6608;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-6606;MetaCyc: PWY-5381;MetaCyc: PWY-7185	"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I"
XP_049794778.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants"
XP_049788511.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_049812422.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049798951.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049789165.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049798179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049793210.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807142.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049802808.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049800782.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049792034.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049789829.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049806107.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-5619078;Reactome: R-HSA-727802	"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars"
XP_049798157.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049806408.1	18	MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-5362517;KEGG: 00010+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-204174;MetaCyc: PWY-5046;KEGG: 00620+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403	"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Propanoate metabolism";"Glycine, serine and threonine metabolism";"Glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Pyruvate metabolism";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)"
XP_049806371.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049813027.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_049792746.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049803191.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807964.1	10	MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587	"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
XP_049810459.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049813871.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049816163.1	5	Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-9020702	"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"Interleukin-1 signaling"
XP_049793008.1	12	Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042	"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)"
XP_049800051.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049801052.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_049788978.1	11	Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253	"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_049811849.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049793086.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049814376.1	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049806494.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049791892.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049813303.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049802529.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049808827.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049809099.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_049811504.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049808208.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway"
XP_049791806.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049810796.1	7	KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485	"Glycerophospholipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PA";"Role of phospholipids in phagocytosis"
XP_049789357.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049804216.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049788539.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_049804245.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049810917.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_049810424.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049800683.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049811318.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049792532.1	10	Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-2197563	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription"
XP_049788557.1	5	Reactome: R-HSA-1234158;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-1234174;Reactome: R-HSA-8849473	"Regulation of gene expression by Hypoxia-inducible Factor";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cellular response to hypoxia";"PTK6 Expression"
XP_049793195.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806076.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049813261.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049790495.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049788916.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_049800461.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049792763.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049809466.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815171.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049792644.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049811975.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049809483.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049791199.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049816111.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_049809579.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049804841.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_049810396.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049803586.1	5	KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4	"Synthesis and degradation of ketone bodies";"Geraniol degradation";"Mevalonate degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_049798810.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539	"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism"
XP_049800834.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_049811247.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049802800.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049801457.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049815213.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049806597.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049811729.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049792882.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049793251.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049803227.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049815735.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049798275.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049799201.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_049815475.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_049789417.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049790665.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049801692.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049794846.1	5	Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049806507.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism"
XP_049802048.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
XP_049811958.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049793216.1	25	Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Cilium Assembly";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins"
XP_049815056.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_049802961.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_049805009.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049805864.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-450408	"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049816613.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789881.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049812645.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049798955.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590	"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Neddylation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling"
XP_049791020.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049793326.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801579.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049801425.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_049803756.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049788789.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_049810653.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049806334.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER"
XP_049815476.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_049795525.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation"
XP_049805767.1	9	MetaCyc: PWY-6682;MetaCyc: PWY-6322;KEGG: 00998+4.1.1.82;MetaCyc: PWY-7510;MetaCyc: PWY-8067;MetaCyc: PWY-7769;MetaCyc: PWY-6839;KEGG: 00440+4.1.1.82;MetaCyc: PWY-5757	"Dehydrophos biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Rhizocticin A and B biosynthesis";"Methylphosphonate biosynthesis";"Phosalacine biosynthesis";"2-aminoethylphosphonate biosynthesis";"Phosphonate and phosphinate metabolism";"Fosfomycin biosynthesis"
XP_049811425.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049789672.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049805040.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049812054.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049811371.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_049814553.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_049809902.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_049815367.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription"
XP_049804101.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483	"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs"
XP_049803830.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Neutrophil degranulation";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049804800.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451	"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049809818.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_049806918.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049797998.1	9	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-7385;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III"
XP_049814889.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049815586.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049816203.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049789601.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049806191.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049815712.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049809252.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_049801205.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049808918.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049805563.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_049812451.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049811106.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049789531.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049810053.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049800990.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_049816432.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049789293.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049804877.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049809669.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049808122.1	8	Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580	"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence"
XP_049796124.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049809121.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049803526.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049813716.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049790687.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049788661.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049793287.1	3	Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271	"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_049789803.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_049792065.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049810569.1	15	MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-8004	"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway I"
XP_049811495.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049802920.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_049806297.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049796343.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049802906.1	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_049788622.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049805005.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049814422.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_049816116.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049811952.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049800454.1	25	Reactome: R-HSA-9616222;Reactome: R-HSA-8877330;Reactome: R-HSA-8939246;Reactome: R-HSA-8951911;Reactome: R-HSA-8941333;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-8940973;Reactome: R-HSA-8936459;Reactome: R-HSA-8939245;Reactome: R-HSA-8939247;Reactome: R-HSA-8941284;Reactome: R-HSA-8941326;Reactome: R-HSA-8949275;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8939256;Reactome: R-HSA-8939242;Reactome: R-HSA-8931987;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-8951936;Reactome: R-HSA-8935964;Reactome: R-HSA-8941332	"Transcriptional regulation of granulopoiesis";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates bone development";"RUNX3 Regulates Immune Response and Cell Migration";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"RUNX3 regulates p14-ARF";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in cell migration"
XP_049792114.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049806683.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049805053.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049792764.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049809093.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668	"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049789494.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049793148.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792605.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049806727.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049802548.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049805088.1	8	Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6803207	"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049807923.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_049794537.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049803046.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049807984.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049809647.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802741.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049811525.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049811402.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy"
XP_049798022.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049791761.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation"
XP_049791313.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_049813148.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049794921.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049800999.1	4	Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_049797652.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II"
XP_049791039.1	34	Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-75955;Reactome: R-HSA-69273;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-6781823;Reactome: R-HSA-73863	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Elongation";"Cyclin A/B1/B2 associated events during G2/M transition";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination"
XP_049791211.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049815730.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_049795240.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049804972.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049788566.1	7	Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-171306	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends"
XP_049799946.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049802142.1	7	MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8	"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism"
XP_049805374.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17	"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism"
XP_049792138.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049812155.1	9	KEGG: 04151+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05165+2.7.11.1;Reactome: R-HSA-446343;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Cell-extracellular matrix interactions";"Human papillomavirus infection";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049811251.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049801843.1	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1	"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_049812450.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049789579.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_049809151.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_049795199.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_049804022.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049791030.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049811524.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509	"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling"
XP_049805419.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919	"Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils"
XP_049815194.1	11	MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049804275.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801409.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049805681.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049799898.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049815585.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049815202.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049788855.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049790900.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049815883.1	32	Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049811851.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049803989.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_049816177.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049816179.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_049809918.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049813041.1	8	MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;KEGG: 00950+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5394;MetaCyc: PWY-6133;Reactome: R-HSA-209905	"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"Folate biosynthesis";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis"
XP_049810052.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049793897.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049813251.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049803939.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826	"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis"
XP_049812885.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-532668;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895	"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Defective CFTR causes cystic fibrosis"
XP_049803210.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_049789384.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_049816303.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049814852.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049794171.1	7	MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7886	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_049813977.1	14	KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-75109;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053	"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II"
XP_049807540.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049801129.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049805680.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049790842.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049805928.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049815747.1	17	Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167246;KEGG: 04660+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Th1 and Th2 cell differentiation";"Tat-mediated elongation of the HIV-1 transcript";"T cell receptor signaling pathway";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049814887.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049805528.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_049811332.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049816877.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049800968.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049815263.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049793011.1	12	MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism"
XP_049803184.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_049805487.1	12	MetaCyc: PWY-601;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-6842	"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II"
XP_049801718.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049790805.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049811942.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049816813.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049814183.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049790712.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049800000.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049808282.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049814239.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049789700.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049801949.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049815732.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_049790747.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-8951664	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation"
XP_049814103.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049808205.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049799272.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049805076.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049800168.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049814156.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049805657.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049812331.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049793592.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049812234.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_049807612.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049797629.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049815648.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049794856.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049813016.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049800690.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049800554.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049810755.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808324.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis"
XP_049793178.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806015.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049810205.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049811252.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049793205.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804047.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_049800369.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815209.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049813775.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049807316.1	4	Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331	"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I"
XP_049805502.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049802245.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-381340	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation"
XP_049813126.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764	"rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination"
XP_049806704.1	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_049804001.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER"
XP_049802843.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049795146.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049803542.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049796823.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_049797347.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_049805140.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757	"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation"
XP_049796862.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis"
XP_049806606.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049810050.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049815035.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049816135.1	18	MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;Reactome: R-HSA-5624138;MetaCyc: PWY-6545;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227	"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Trafficking of myristoylated proteins to the cilium";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_049816106.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_049802426.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049795426.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049794784.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049799876.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237	"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2"
XP_049798477.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049807211.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049814163.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"Macroautophagy";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049801534.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049808388.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049791033.1	6	MetaCyc: PWY-7077;MetaCyc: PWY-7395;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25	"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049800041.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049806122.1	5	Reactome: R-HSA-70688;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88	"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049790190.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049799743.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049808494.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049809867.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_049797101.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-166208	"Deadenylation of mRNA";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling"
XP_049814241.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049791200.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_049804458.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091	"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells"
XP_049811171.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049816782.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049790880.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_049810675.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049792194.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049803059.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049801566.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049815188.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049807717.1	16	Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-164939;Reactome: R-HSA-196025;Reactome: R-HSA-177504	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"Nef mediated downregulation of CD28 cell surface expression";"Formation of annular gap junctions";"Retrograde neurotrophin signalling"
XP_049799741.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049800366.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_049807244.1	10	MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_049806078.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049788673.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091	"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching"
XP_049788891.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049800552.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049809906.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_049814394.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049815498.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049804857.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049795147.1	6	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation"
XP_049797992.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation"
XP_049795473.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_049792647.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049801383.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049805115.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049795461.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214	"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049816099.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049801047.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049814408.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049801011.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049789069.1	20	KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7726	"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_049812687.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741	"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049809895.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-606279	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049799647.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049807010.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049816340.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049812956.1	6	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"ESR-mediated signaling"
XP_049806536.1	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II"
XP_049811607.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049814106.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049815790.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049805648.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049802664.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049815898.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049791974.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049808842.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808657.1	13	Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662	"Keratan sulfate degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism"
XP_049791958.1	4	Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719377	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_049814631.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049792906.1	7	Reactome: R-HSA-1483226;MetaCyc: PWY-6352;MetaCyc: PWY-7625;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11	"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Inositol phosphate metabolism"
XP_049813449.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952	"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation"
XP_049811426.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049789587.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049794259.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049809964.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_049791785.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049811061.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049803027.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049814222.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049788562.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049788509.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_049797642.1	15	MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171	"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis"
XP_049810418.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049791622.1	15	Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Ca2+ pathway"
XP_049815716.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049804448.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049805346.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049791537.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049794257.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049816301.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049803696.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049815525.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049804975.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049811386.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049801119.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-380972	"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049792735.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291	"HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C"
XP_049802788.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049804695.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049813158.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049805616.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049807319.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049815664.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049807716.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049797459.1	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049808835.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812082.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049790700.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049807478.1	10	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Sphingolipid metabolism"
XP_049811125.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049797624.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049811235.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_049793476.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_049801368.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049814744.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events"
XP_049805833.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049816792.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049815646.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049808464.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049813638.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049792157.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049807854.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793724.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049812556.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049803201.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049802528.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049802573.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049791792.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049804124.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_049788597.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049797704.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049804647.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049814155.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049812820.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049800985.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049815151.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049810624.1	13	MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101	"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation"
XP_049791982.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049811803.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6807505	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes"
XP_049815107.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049800662.1	9	Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411	"Polymerase switching";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere"
XP_049808479.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049804385.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049808010.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049789957.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049800448.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800368.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049808380.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791975.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049801224.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049801709.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_049807084.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049791531.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_049808520.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049800729.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049815318.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049789695.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049811512.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_049811811.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049805729.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049809404.1	11	KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-5675;MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-6964;MetaCyc: PWY-381	"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)"
XP_049800514.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_049810912.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049804550.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049814255.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049806509.1	11	Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657	"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes"
XP_049810659.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049802736.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-3232142	"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins"
XP_049803946.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049816822.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049807419.1	8	Reactome: R-HSA-606279;Reactome: R-HSA-6783310;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049813288.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183	"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_049795670.1	5	Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702	"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049807740.1	18	KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642;MetaCyc: PWY-6638	"Cysteine and methionine metabolism";"Arginine biosynthesis";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Sulfolactate degradation III"
XP_049809413.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049793336.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049802866.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_049815468.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049816221.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668	"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049790890.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049801791.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049802767.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_049816684.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_049793993.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049815316.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049807611.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803912.1	10	MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7571;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10	"Mevalonate pathway I";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies"
XP_049812147.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049814393.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;Reactome: R-HSA-379716;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049805391.1	24	Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-392451	"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"G alpha (q) signalling events";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"G-protein activation";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma"
XP_049816775.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049808138.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
XP_049789316.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049790305.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049814486.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-442982	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049795194.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049812385.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049803044.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049803483.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049809999.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049803506.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049812123.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049794541.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049813338.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049812163.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049799216.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049789699.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049815948.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049814554.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_049796591.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049814853.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049804102.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins"
XP_049791679.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049793849.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049804849.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049790472.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049799619.1	13	Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764	"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling"
XP_049800831.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049807143.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049799340.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323	"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling"
XP_049791721.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049813468.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049797963.1	1	Reactome: R-HSA-3000484	"Scavenging by Class F Receptors"
XP_049815251.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049795109.1	4	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049788780.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_049789820.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_049813206.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049803028.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049812413.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_049807868.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy"
XP_049809092.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049807443.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049790511.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049810551.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049816808.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049807080.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049790634.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism"
XP_049789333.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049804856.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049808151.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049800526.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049796842.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049803914.1	10	MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-6174;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;Reactome: R-HSA-1989781	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression"
XP_049812013.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049801999.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049813240.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_049809119.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049794909.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049788896.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049815199.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049802737.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism"
XP_049805929.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049788737.1	10	KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_049791019.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_049804272.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807682.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049790639.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoate metabolism"
XP_049812238.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_049793366.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049814119.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807325.1	14	Reactome: R-HSA-380284;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-2467813;Reactome: R-HSA-5620912;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-9648025	"Loss of proteins required for interphase microtubule organization from the centrosome";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Separation of Sister Chromatids";"Anchoring of the basal body to the plasma membrane";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation"
XP_049805347.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619	"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis"
XP_049797576.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC";"Glycerophospholipid metabolism"
XP_049794175.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049813207.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049814897.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5870;KEGG: 00130+1.14.99.60	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049802332.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_049807578.1	10	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049807848.1	11	Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-1268020;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Mitochondrial protein import";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_049808504.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049793096.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049792547.1	7	Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_049807999.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049792416.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049791472.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049812938.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049802891.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049792209.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049789856.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049802778.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_049793707.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_049799511.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049800601.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049816524.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049808495.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049810707.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_049800350.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049791196.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049816687.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_049810354.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends"
XP_049815130.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation"
XP_049789894.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049790286.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_049803352.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049807794.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801708.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049815072.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049816164.1	5	Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-205043	"NF-kB is activated and signals survival";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus"
XP_049810639.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events"
XP_049815040.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049805466.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_049808793.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805785.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049807356.1	5	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049800075.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049801253.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049807157.1	6	MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370	"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism"
XP_049795743.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816769.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049807548.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049812573.1	6	Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66	"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049793734.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049792601.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-430039	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_049790576.1	7	MetaCyc: PWY-8004;MetaCyc: PWY-5514;Reactome: R-HSA-71336;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31	"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Pentose phosphate pathway"
XP_049803508.1	17	Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-1169091;Reactome: R-HSA-450302;Reactome: R-HSA-5689880;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-202424;Reactome: R-HSA-450321;Reactome: R-HSA-4086398;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-9645460;Reactome: R-HSA-937042	"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of NF-kappaB in B cells";"activated TAK1 mediates p38 MAPK activation";"Ub-specific processing proteases";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ca2+ pathway";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex"
XP_049789488.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049801403.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049789497.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_049792671.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049798374.1	1	Reactome: R-HSA-6805567	"Keratinization"
XP_049813354.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049795427.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049816601.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049805271.1	2	Reactome: R-HSA-2129379;Reactome: R-HSA-189085	"Molecules associated with elastic fibres";"Digestion of dietary carbohydrate"
XP_049807544.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049810643.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049800863.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049803597.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049788998.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049795026.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049800354.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049799699.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049805043.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines"
XP_049788742.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049799151.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_049815694.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"SUMOylation of DNA methylation proteins"
XP_049803556.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049808372.1	10	Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300	"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors"
XP_049795628.1	5	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_049793777.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049790871.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_049810715.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049799661.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_049791915.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase"
XP_049795046.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049812983.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049789634.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049801189.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049799720.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049800068.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049807646.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049804549.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049816573.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049802612.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049789168.1	14	MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7279	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_049789847.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049802295.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049806538.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_049793204.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049795853.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049813937.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049792002.1	5	Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049799255.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049815824.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049805771.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049805961.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049797411.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049811500.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049789323.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049813123.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049813014.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049813029.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049806415.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049809389.1	11	KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-6964;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-5675	"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)"
XP_049803572.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049791912.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049806794.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049799075.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049789751.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049807089.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049811129.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049808062.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049788729.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049805263.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_049812263.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049792768.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049793681.1	6	Reactome: R-HSA-8939211;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"ESR-mediated signaling";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049791080.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049788951.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049816305.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049809433.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801792.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049812246.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049816244.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049797103.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049802724.1	20	Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"mTORC1-mediated signalling";"mTOR signalling";"PIP3 activates AKT signaling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"Macroautophagy";"Thermogenesis";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049788987.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049812791.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049808598.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049800515.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049792139.1	27	Reactome: R-HSA-167242;Reactome: R-HSA-111367;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-159230;Reactome: R-HSA-975956;Reactome: R-HSA-159227;Reactome: R-HSA-77588;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-77595;Reactome: R-HSA-191859;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-9010553	"Abortive elongation of HIV-1 transcript in the absence of Tat";"SLBP independent Processing of Histone Pre-mRNAs";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of the SLBP independent Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Processing of Intronless Pre-mRNAs";"snRNP Assembly";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs"
XP_049794884.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049801630.1	6	Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import"
XP_049810489.1	7	Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation"
XP_049797449.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049805628.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049792045.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049798301.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049791072.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_049816856.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049791760.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events"
XP_049788656.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049805177.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049811200.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049806646.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_049814533.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049804572.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_049807551.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049805714.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049802835.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_049805472.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_049798898.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049792987.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1"
XP_049789612.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049808665.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049810655.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049792770.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049803475.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049800019.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049803988.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I"
XP_049795171.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049801226.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049794025.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049794733.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049810788.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049795451.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049805851.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049814073.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049801697.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049811629.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049812811.1	15	Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)"
XP_049801458.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049793061.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049789904.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049815609.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049800529.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049795449.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049804129.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049804911.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_049811701.1	6	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_049795922.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049805793.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
XP_049815226.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049812584.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049813538.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049811562.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_049794595.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049809614.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049804358.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_049803230.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_049806373.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049805411.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049791944.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049804380.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049812816.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049802910.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-110314	"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049812732.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049791667.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049801941.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049793406.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049810961.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049806151.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049805464.1	12	KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Sucrose biosynthesis II"
XP_049793905.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049802639.1	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_049791918.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase"
XP_049811661.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism"
XP_049799040.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_049816926.1	3	MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049800409.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049806594.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135	"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation"
XP_049815791.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049802486.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049793107.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049804318.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049796123.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_049794864.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049803935.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049799063.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049812235.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049811266.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049809110.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049793557.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049803180.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence"
XP_049790863.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1660499;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95	"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism"
XP_049791042.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723	"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation"
XP_049791154.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049809576.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049811417.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_049808345.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049801735.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049805024.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049809467.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793114.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049797703.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049802713.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049791742.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049810871.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049795343.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049807549.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049795921.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049811063.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049792542.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049810610.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_049795718.1	16	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-201722	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex"
XP_049815225.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049815185.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049792033.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049806689.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813879.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809850.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615	"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation"
XP_049797956.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen degradation"
XP_049791618.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049800841.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049815152.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049815049.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809255.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049788754.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049808267.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049789687.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049809482.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_049811521.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049806296.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049796995.1	5	Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20	"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes"
XP_049810480.1	29	Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167172	"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome"
XP_049793951.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_049811664.1	8	KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis"
XP_049802611.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049810496.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-191859;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation"
XP_049814249.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049793228.1	5	Reactome: R-HSA-964975;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_049789595.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049797982.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049815561.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049807762.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049814734.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-163615	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation"
XP_049812741.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049816120.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049789268.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex"
XP_049797856.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049797654.1	6	MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124	"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II"
XP_049804894.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049790729.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246	"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript"
XP_049794731.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049795268.1	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-3371511;Reactome: R-HSA-110312	"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"HSF1 activation";"Translesion synthesis by REV1"
XP_049788917.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_049790930.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425	"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049794865.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049789782.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049793270.1	3	KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_049789760.1	4	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270	"Glycerolipid metabolism";"Glycerol degradation I";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate"
XP_049807826.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049810016.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049802415.1	18	Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7210	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049808334.1	9	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049794092.1	8	MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049816328.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049812005.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049815310.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815957.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7736;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5122	"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Geranyl diphosphate biosynthesis"
XP_049794734.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049795284.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049810227.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049812575.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049796201.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049792161.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049795344.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049806577.1	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049802772.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049794389.1	6	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation"
XP_049805108.1	8	Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049799288.1	11	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_049804161.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events"
XP_049794287.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049811380.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049790250.1	12	KEGG: 00660+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-5744;MetaCyc: PWY-7295;MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7854;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-6728	"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Glyoxylate assimilation";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Methylaspartate cycle"
XP_049806638.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049815570.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049793209.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793945.1	14	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7589	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_049797758.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802388.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049800356.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792235.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049801459.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049793318.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049793415.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049812425.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049793976.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816750.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049814286.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049790879.1	3	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_049793850.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_049792886.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049813069.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049802101.1	8	MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301	"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis"
XP_049791060.1	8	KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-6791055;Reactome: R-HSA-71336;Reactome: R-HSA-163754;MetaCyc: PWY-1861	"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_049788817.1	7	MetaCyc: PWY-5265;MetaCyc: PWY-6470;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;Reactome: R-HSA-4549356	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2"
XP_049790840.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049806669.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_049788540.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049815792.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049805440.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_049797106.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049793292.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049815737.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids"
XP_049794832.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049812135.1	6	KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-446199;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I"
XP_049803377.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049792224.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049804119.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049802363.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434	"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"Gap junction assembly";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049801654.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049800119.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049807675.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_049800788.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049814748.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049814557.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553	"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs"
XP_049814659.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
XP_049813097.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049802073.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy"
XP_049805967.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049816215.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049794385.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049793241.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049790713.1	5	MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_049816748.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049792102.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049808355.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049794446.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049814245.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049811992.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049791532.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_049809795.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049793310.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049816882.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049808583.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049803469.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049807772.1	18	Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;MetaCyc: PWY-7511;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"Protein ubiquitination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049800145.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049792111.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049807539.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049801281.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_049803140.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_049816783.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049793214.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_049799514.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332	"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_049788551.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049790364.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049799747.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814669.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049806991.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049808246.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049806444.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049795355.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Signal transduction by L1";"Neutrophil degranulation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes"
XP_049816231.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049804614.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2"
XP_049797422.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049789113.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049797472.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III"
XP_049790473.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049793145.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806169.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049804645.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049810974.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049802398.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049812804.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049811304.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049811121.1	2	Reactome: R-HSA-210746;Reactome: R-HSA-210745	"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells"
XP_049797719.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049801037.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049814194.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049791851.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049803507.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049800628.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049813651.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049812787.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049809343.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049804016.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049814158.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049803579.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049816107.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049800882.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049812985.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049812452.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049807905.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829	"Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy"
XP_049812860.1	6	MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_049813359.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase"
XP_049816708.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049807344.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049804945.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
YP_010401640.1	7	Reactome: R-HSA-611105;MetaCyc: PWY-4302;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2	"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation"
XP_049809053.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049808506.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049795700.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049792451.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049811335.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049801583.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049812968.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288	"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_049792606.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_049806153.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049811665.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049802745.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049795650.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049806575.1	4	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_049801417.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049813344.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049798323.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049811814.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049806307.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829	"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049807928.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049808467.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049794252.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_049806395.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-901032	"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
XP_049812212.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events"
XP_049811602.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_049792728.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_049807444.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049800016.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813120.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049812612.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
YP_010401632.1	7	MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-6692;Reactome: R-HSA-6799198	"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Complex I biogenesis"
XP_049812105.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049791130.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049802675.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049806014.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_049814990.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049794727.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049804725.1	6	Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic"
XP_049788936.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049806763.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing"
XP_049811717.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049816235.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049801435.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049811518.1	52	Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-167290;Reactome: R-HSA-76071;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-72163	"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway"
XP_049808927.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049801935.1	5	KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241	"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import"
XP_049814409.1	3	KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17	"Purine metabolism";"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism"
XP_049796444.1	4	Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-432720	"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
XP_049815205.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049813030.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049811506.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049815917.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049807472.1	10	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome"
XP_049789697.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-9603505;Reactome: R-HSA-167242	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"NTRK3 as a dependence receptor";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049815048.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807577.1	10	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Sphingolipid metabolism"
XP_049801371.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049794808.1	10	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-71737;Reactome: R-HSA-9640463	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Pyrophosphate hydrolysis";"Wax biosynthesis"
XP_049816419.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049807933.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049814998.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815260.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049806651.1	6	KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049800182.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_049794217.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049810001.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049813579.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049803793.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049802389.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049804472.1	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780	"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome"
XP_049808839.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049797582.1	24	Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-437239	"Gap junction assembly";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1"
XP_049816246.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049789368.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049808695.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_049805340.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049811215.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049806530.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049807024.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049799675.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-4086398;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-4608870	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"Ca2+ pathway";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins"
XP_049812084.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049811199.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-882	"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_049815420.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049799143.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049811483.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049802780.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_049803194.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812075.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049804681.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_049812692.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049799433.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Purine metabolism"
XP_049802570.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049815806.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049803404.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_049793437.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049793009.1	12	Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13	"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis"
XP_049813406.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049788818.1	3	MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_049804851.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049802364.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833	"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly"
XP_049793179.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049797428.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049800575.1	17	Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-69202;Reactome: R-HSA-9616222;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-111448	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Cyclin E associated events during G1/S transition";"Transcriptional regulation of granulopoiesis";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Activation of NOXA and translocation to mitochondria"
XP_049815286.1	6	KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151	"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049798350.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049797900.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590	"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling"
XP_049792760.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049811263.1	7	Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472	"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049794424.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids"
XP_049810363.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049805463.1	12	MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9	"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Stachyose degradation";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism"
XP_049809197.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049795923.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049806343.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049815210.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049812203.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049803024.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049815659.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-7141	"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis"
XP_049811875.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049795733.1	9	KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1	"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes"
XP_049815006.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049804459.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664	"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Neddylation"
XP_049795806.1	29	Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-5358606;Reactome: R-HSA-176187;Reactome: R-HSA-110314	"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049815511.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049807767.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049796642.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_049815856.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049803815.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-975634;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Ether lipid metabolism";"alpha-Linolenic acid metabolism"
XP_049797452.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049811971.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049790869.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049801369.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049804613.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049793494.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049791783.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049795422.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049805308.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049790907.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049816017.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73780;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049804655.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049799512.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049802047.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines"
XP_049793297.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_049790964.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-5099900	"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4"
XP_049805940.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_049793711.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049792076.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049812587.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174154	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin"
XP_049810433.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049805659.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049789455.1	8	KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-6556;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_049797653.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_049807452.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049814248.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049811829.1	13	MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III"
XP_049801427.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049802139.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_049802783.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815291.1	8	Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
XP_049797961.1	1	Reactome: R-HSA-156581	"Methylation"
XP_049810479.1	29	Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_049809675.1	57	Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Regulation of RAS by GAPs"
XP_049795716.1	16	Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049808113.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049793108.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049788876.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049796996.1	5	MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;Reactome: R-HSA-196757	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines"
XP_049800829.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049790406.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049814499.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955	"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049788634.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049793661.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049812485.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049807064.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211981	"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"PPARA activates gene expression";"Xenobiotics"
XP_049805572.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_049792254.1	4	KEGG: 00440+2.6.1.37;Reactome: R-HSA-9033241;MetaCyc: PWY-6832;Reactome: R-HSA-389661	"Phosphonate and phosphinate metabolism";"Peroxisomal protein import";"2-aminoethylphosphonate degradation II";"Glyoxylate metabolism and glycine degradation"
XP_049815611.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049802395.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049798298.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049808091.1	6	MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049792955.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110373	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
XP_049801475.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049794737.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049788928.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049815845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805746.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049810402.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049793224.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049801001.1	17	MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-7115	"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Methane metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049805564.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049801519.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049805418.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919	"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils"
XP_049812237.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_049790905.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049813534.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049810286.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049808233.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049815201.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049810232.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049797419.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049814776.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_049803934.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049812544.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049802006.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049805698.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049802775.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049793189.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814280.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049803835.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049811330.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049809827.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049791081.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049805965.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049790506.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049801696.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_049794408.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049789101.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_049802417.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049811246.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049789046.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049811695.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049810356.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049807773.1	8	MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-7400;KEGG: 00250+4.3.2.1	"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Canavanine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism"
XP_049800820.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049808083.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_049803473.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049812437.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049802471.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049809390.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_049797640.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-8004	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway I"
XP_049808655.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Other glycan degradation"
XP_049792118.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049796436.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049798885.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049791134.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049802510.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049791714.1	7	KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_049794989.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049796204.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049791021.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049814490.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049792789.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049808544.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_049792646.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049790093.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049789530.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049815571.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049810310.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049791034.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049788520.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response"
XP_049791767.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049814179.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049811692.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049791782.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049803225.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049813448.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962	"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex"
XP_049788915.1	10	Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-72702	"ABC-family proteins mediated transport";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition"
XP_049802657.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049789937.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_049791888.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049803399.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_049790519.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049789229.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049811938.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_049809322.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049797714.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_049808537.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049803901.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049812023.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049805438.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049808034.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049807541.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049793372.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801	"Linoleic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PS"
XP_049797677.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049801682.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049809117.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049807973.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049791726.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049797626.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049808538.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_049814125.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049800975.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049802400.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049807145.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049808434.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_049814779.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049807372.1	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_049800527.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049813040.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049805055.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_049804698.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049804573.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049804009.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049813191.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049812456.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-381038	"Protein ubiquitination";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes"
XP_049800525.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049813176.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049809776.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049790694.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049811956.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808212.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049791016.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_049788692.1	8	KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism"
XP_049803442.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_049814556.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049806185.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_049800866.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049813407.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049797882.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049810185.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049792434.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049789096.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049799053.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049789991.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049800661.1	9	Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411	"Polymerase switching";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere"
XP_049792976.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049802804.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049794316.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049789610.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049793125.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049807774.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049790718.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049798475.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049810667.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_049789793.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813074.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049812494.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049788768.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049804870.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_049812828.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049789861.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049813250.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049791507.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049814891.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049814823.1	13	MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation"
XP_049810466.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049805761.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049801693.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049807002.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049807780.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049793530.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049814662.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275	"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation"
XP_049790811.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049806216.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049810674.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049790548.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809755.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049805633.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049788850.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049793033.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_049794210.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049795155.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_049804752.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049816385.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049793828.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049801110.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049791338.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_049789438.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049801130.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049809373.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049789052.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-110362	"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair"
XP_049789867.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_049789416.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049805979.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049814972.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049793722.1	26	Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-174417;Reactome: R-HSA-69205;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6804114;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-8866654;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565	"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"Telomere C-strand (Lagging Strand) Synthesis";"G1/S-Specific Transcription";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049810481.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049793034.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049791495.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_049811834.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-114608	"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation"
XP_049806478.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813060.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049790994.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049794830.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049802854.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049812205.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049804066.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049814473.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049807727.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049814819.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_049816059.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049791945.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049801269.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049803800.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049807256.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804987.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049793254.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049812772.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_049807775.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049804659.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049811662.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism"
XP_049813552.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_049794773.1	40	Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-76042	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049804718.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049808253.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049802899.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049795411.1	9	MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_049803827.1	14	KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I"
XP_049816874.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049789538.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049807449.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049807663.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049807887.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_049805748.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049795399.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049793529.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049813324.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049801247.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049795925.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049814446.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049807373.1	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_049792207.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049791663.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049805025.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049811894.1	5	Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049814450.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049812460.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049805990.1	16	MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.4;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Itaconate degradation";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle"
XP_049799546.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049813451.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_049810567.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049791490.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049800440.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049814254.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049814387.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049810287.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049803904.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049813472.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049802468.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049807805.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049810438.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049805045.1	10	KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"RSK activation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Thermogenesis"
XP_049800450.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049797329.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-9619483	"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Lipophagy";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs"
XP_049789222.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_049799145.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049790398.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049805305.1	14	MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7782	"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis"
XP_049789257.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049797413.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049792798.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049795156.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049808717.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_049811880.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049801380.1	1	Reactome: R-HSA-73943	"Reversal of alkylation damage by DNA dioxygenases"
XP_049802606.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049812493.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049789495.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events"
XP_049814373.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049801752.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049794258.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049800449.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793123.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049790379.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049794918.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_049803895.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291	"HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C"
XP_049815762.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049803049.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049815355.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049798026.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049811477.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA 3'-end processing"
XP_049792030.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049795560.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049808425.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049803852.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049804663.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049790610.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049792112.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049816791.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049816773.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_049808830.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049816056.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049804481.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756;Reactome: R-HSA-936440	"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling"
XP_049808481.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049794782.1	4	MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14	"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism"
XP_049815916.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049813346.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049801629.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049816268.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049793170.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049812291.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049788787.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT"
XP_049811735.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049793160.1	6	Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis"
XP_049806826.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049791635.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049816019.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049816855.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049800292.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2"
XP_049803797.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530	"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II"
XP_049808209.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex"
XP_049816283.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049810186.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049793176.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801408.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049805483.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049789483.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049811702.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_049814169.1	11	MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-6859;KEGG: 00900+5.3.3.2;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7102;MetaCyc: PWY-7391;MetaCyc: PWY-7560;MetaCyc: PWY-6174;MetaCyc: PWY-7524	"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)";"Isoprene biosynthesis II (engineered)";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)"
XP_049793180.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049810647.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049801280.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_049809823.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_049795423.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049805339.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049791937.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049792925.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049813930.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049812541.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049801399.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_049791400.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049815702.1	13	Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-216083	"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"NCAM1 interactions";"Signaling by PDGF";"Extracellular matrix organization";"Laminin interactions";"Collagen degradation";"Anchoring fibril formation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions"
XP_049816814.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049793191.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811983.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049809996.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049801507.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049812607.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling"
XP_049813139.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049814663.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049812897.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049792881.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049805516.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049812455.1	5	Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-381038	"Hedgehog ligand biogenesis";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes"
XP_049800246.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049792953.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110373	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
XP_049813403.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049795413.1	9	Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events"
XP_049811130.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049813957.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049812444.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049806474.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049788874.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049807688.1	12	KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6613;Reactome: R-HSA-196780	"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Biotin transport and metabolism"
XP_049799938.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049793324.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049808605.1	11	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2"
XP_049803402.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_049808207.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049794197.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049803173.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049815567.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_049793049.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_049793099.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049791646.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049811078.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049810571.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_049806438.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine"
XP_049803233.1	8	Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049805004.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049799076.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049793532.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049793328.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049816214.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049803391.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049793470.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_049808330.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049811354.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049792888.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049793076.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049803668.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049790014.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049807512.1	9	KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533	"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis"
XP_049805696.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049804723.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049816912.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation"
XP_049815160.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_049791662.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049804000.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway"
XP_049797590.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049797630.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049814385.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation"
XP_049801522.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049801376.1	1	Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049815034.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049810645.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049792063.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049815348.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_049808602.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049814104.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049789111.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_049793079.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049807264.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_049815849.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_049812134.1	6	Reactome: R-HSA-446199;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33	"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis"
XP_049807506.1	9	MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18	"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes"
XP_049802827.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049804535.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049793092.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049801787.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049801529.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049810487.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049793175.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816228.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049789745.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049806298.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049810101.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815568.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_049797756.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049789518.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049799398.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800828.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049807963.1	10	MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-6453	"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis"
XP_049800359.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049798095.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049793474.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049793309.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049808812.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791447.1	22	MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7727;MetaCyc: PWY-7601;MetaCyc: PWY-7049;MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049811458.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis"
XP_049792926.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049816709.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049807429.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_049789056.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049813646.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049808823.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813525.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049791678.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049804088.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049805834.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049805880.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049806128.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_049795195.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049810461.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049810583.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_049803832.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049811374.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049791272.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049816472.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049808076.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049812137.1	24	Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-418217	"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G-protein activation";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"G alpha (q) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta"
XP_049794380.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_049805158.1	7	KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3	"One carbon pool by folate";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_049794735.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049802958.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049812698.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049814691.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049815944.1	13	MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049812511.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049815729.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_049797726.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049813402.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049807268.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049807708.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700	"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_049795144.1	10	MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6366;MetaCyc: PWY-6362;MetaCyc: PWY-6365;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol"
XP_049812934.1	9	MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Preq0 biosynthesis"
XP_049788984.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049806430.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049808325.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis"
XP_049792113.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049791934.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049788962.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049798266.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320	"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Gap junction assembly";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Kinesins";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes"
XP_049801650.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049810359.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049802046.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049806795.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_049799983.1	9	MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484	"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)"
XP_049805425.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_049793508.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049809348.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049815908.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049791666.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049793360.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049792508.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792766.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049812782.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049815724.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
XP_049804048.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049802771.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049790908.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049806179.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_049815706.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination"
XP_049812730.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159230	"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA"
XP_049812997.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_049804213.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049808813.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049815865.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049813748.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049811946.1	4	KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030	"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_049804486.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049807604.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049815264.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049794396.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049802309.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049789133.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049788921.1	10	Reactome: R-HSA-913709;MetaCyc: PWY-7921;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;MetaCyc: PWY-7661;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922	"O-linked glycosylation of mucins";"Protein O-mannosylation I (yeast)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049810443.1	13	MetaCyc: PWY-6545;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_049791890.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049800619.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049793059.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049806639.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049802536.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049805416.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049811128.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049793697.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049810458.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049809843.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049792551.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049800804.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049812124.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049800892.1	18	Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_049808816.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803585.1	5	KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4	"Synthesis and degradation of ketone bodies";"Geraniol degradation";"Mevalonate degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_049800780.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049792887.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049790338.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049792918.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049793150.1	21	Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-5357956;Reactome: R-HSA-937041;Reactome: R-HSA-1810476;Reactome: R-HSA-5603027;Reactome: R-HSA-1236974;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-5603029;Reactome: R-HSA-937039;Reactome: R-HSA-168927;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-933542;Reactome: R-HSA-933543;Reactome: R-HSA-5607764;Reactome: R-HSA-5602636;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-5357905	"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR1-induced NFkappaB signaling pathway";"IKK complex recruitment mediated by RIP1";"RIP-mediated NFkB activation via ZBP1";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"ER-Phagosome pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"IkBA variant leads to EDA-ID";"IRAK1 recruits IKK complex";"TICAM1, RIP1-mediated IKK complex recruitment";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"TRAF6 mediated NF-kB activation";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"CLEC7A (Dectin-1) signaling";"IKBKB deficiency causes SCID";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"Regulation of TNFR1 signaling"
XP_049791426.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_049808427.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049798034.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049794785.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049805644.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_049814105.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049791713.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation"
XP_049815940.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049802848.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049812476.1	10	Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;MetaCyc: PWY-7394;Reactome: R-HSA-977225	"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Amyloid fiber formation"
XP_049803058.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332	"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_049797915.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049812784.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049792001.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049789594.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049809596.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049788584.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_049807107.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
YP_010401634.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049815289.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049809279.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049799346.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049805486.1	12	MetaCyc: PWY-6842;MetaCyc: PWY-1187;MetaCyc: PWY-7901;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-2821;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-601	"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan"
XP_049809132.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049789939.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049808597.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049801725.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049810791.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049816825.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049800798.1	58	Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5689901;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Metalloprotease DUBs";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints"
XP_049804680.1	8	MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5;KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-7400	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)"
XP_049813172.1	4	MetaCyc: PWY-6823;MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12	"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049811255.1	15	Reactome: R-HSA-9665244;Reactome: R-HSA-9665251;Reactome: R-HSA-9652282;Reactome: R-HSA-9665233;Reactome: R-HSA-9664565;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665247;Reactome: R-HSA-5637810;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285	"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2"
XP_049801706.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049788976.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049802799.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049788919.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049810213.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049801225.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049815813.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049815259.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049811485.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049805515.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049815146.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049800444.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049816054.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049793158.1	6	Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis"
XP_049802841.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049801578.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049793338.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049803640.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049799218.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049792672.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049811265.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049797841.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049814697.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_049807515.1	8	KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18	"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450"
XP_049799042.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049791752.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049811987.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049793082.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049793705.1	12	MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-6683;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25	"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenate reduction";"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Selenocompound metabolism";"Purine metabolism"
XP_049804988.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049806685.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049804468.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-532668;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_049806242.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_049805465.1	12	MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9	"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Stachyose degradation";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049788619.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053	"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis II"
XP_049812506.1	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
XP_049791220.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049798953.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_049794369.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049808204.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049801572.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944	"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2"
XP_049805161.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049792892.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049803505.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049812945.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049812893.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_049804984.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049812949.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049804736.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480	"Scavenging by Class H Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"VLDL assembly";"Retinoid metabolism and transport";"LDL clearance";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class B Receptors";"LDL remodeling";"Chylomicron remodeling";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors"
XP_049792420.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049788567.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_049791563.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049791588.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049816638.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049791339.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049789791.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049801937.1	4	KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049813297.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049790676.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049804569.1	6	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9640463	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis"
XP_049808389.1	7	KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097;MetaCyc: PWY-2942;MetaCyc: PWY-8088;MetaCyc: PWY-2941;KEGG: 00300+4.3.3.7;Reactome: R-HSA-389661	"Monobactam biosynthesis";"L-lysine biosynthesis VI";"L-lysine biosynthesis III";"Dipicolinate biosynthesis";"L-lysine biosynthesis II";"Lysine biosynthesis";"Glyoxylate metabolism and glycine degradation"
XP_049815162.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049798311.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_049810410.1	11	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_049811115.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049814489.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_049788829.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation"
XP_049795377.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049793093.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049807567.1	4	MetaCyc: PWY-5874;Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937	"Heme degradation I";"Heme degradation";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport"
XP_049810469.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049788986.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049791374.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049799943.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049793471.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049793067.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049807528.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049790909.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049812984.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049809582.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049800787.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049808781.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049795350.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-1483191	"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Synthesis of PC"
XP_049804311.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-176187	"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress"
XP_049798961.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049807636.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049809903.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_049797112.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049808846.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805067.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_049801840.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049813201.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049801743.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049801032.1	7	KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_049801520.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049808008.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049800686.1	4	Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049790425.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049802428.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049812486.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049794613.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049816534.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049816078.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049800114.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049811556.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_049814109.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049814369.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418	"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex"
XP_049791214.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049802240.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049807895.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049790832.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168333	"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049816903.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049810066.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049800768.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049790715.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049805452.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049816101.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_049793469.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049809979.1	31	MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-6113;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWY-5142;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;MetaCyc: PWY-6799;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5147;MetaCyc: PWY-8049	"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"Superpathway of mycolate biosynthesis";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Biotin metabolism";"Oleate biosynthesis I (plants)";"Pederin biosynthesis"
XP_049801396.1	17	KEGG: 05165+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-176187	"Human papillomavirus infection";"Fanconi Anemia Pathway";"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress"
XP_049793128.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-180746	"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein"
XP_049803441.1	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
XP_049814180.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049794091.1	8	KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7198	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049803400.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_049814666.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148	"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049790036.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049791133.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176407	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049804761.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-2173796;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6807505	"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes"
XP_049803226.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049805471.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049797880.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049794204.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049810925.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049801498.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy"
XP_049793992.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_049803836.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049806123.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049790635.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism"
XP_049790895.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049795164.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122	"Synthesis of PC";"Neutrophil degranulation";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049789945.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_049803274.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049799688.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049790160.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049802478.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049806634.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049794045.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049812653.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049791150.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049791981.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049806431.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049808266.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_049792725.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049812884.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049800816.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049808728.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049815172.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049815057.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049808203.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049806684.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049811498.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049804981.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049803154.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049791651.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)"
XP_049806045.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049802100.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis"
XP_049805792.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049791387.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049803363.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049808693.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049800657.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049791744.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049804734.1	19	Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888	"Scavenging by Class B Receptors";"Chylomicron remodeling";"Platelet sensitization by LDL";"LDL remodeling";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"VLDL clearance";"VLDL assembly";"Chylomicron clearance";"LDL clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly"
XP_049812392.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_049805226.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_049813063.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049802925.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_049809816.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049801040.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_049807263.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049796075.1	14	MetaCyc: PWY-1622;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00680+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;MetaCyc: PWY-5497	"Formaldehyde assimilation I (serine pathway)";"One carbon pool by folate";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Folate polyglutamylation";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Glycine betaine degradation I";"Photorespiration ";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)"
XP_049801423.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049793593.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049815899.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_049815193.1	11	MetaCyc: PWY-7206;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049807481.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049810660.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049792165.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4	"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism"
XP_049809215.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049793736.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049796641.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049791424.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_049807765.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049815290.1	8	MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway I";"Cholesterol biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_049801361.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_049789846.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049805171.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425	"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049811520.1	52	Reactome: R-HSA-73780;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-203927	"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"MicroRNA (miRNA) biogenesis"
XP_049800456.1	25	Reactome: R-HSA-8936459;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8939243;Reactome: R-HSA-8941333;Reactome: R-HSA-8951911;Reactome: R-HSA-8939246;Reactome: R-HSA-8877330;Reactome: R-HSA-9616222;Reactome: R-HSA-8935964;Reactome: R-HSA-8941332;Reactome: R-HSA-8951936;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-8931987;Reactome: R-HSA-8939242;Reactome: R-HSA-8939256;Reactome: R-HSA-8878166;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8949275;Reactome: R-HSA-8941326;Reactome: R-HSA-8939247;Reactome: R-HSA-8941284;Reactome: R-HSA-8939245	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in cell migration";"RUNX3 regulates p14-ARF";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation by RUNX2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in BCR signaling"
XP_049806535.1	7	MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-7238	"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Glycogen degradation II";"Sucrose biosynthesis II"
XP_049814371.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation"
XP_049798035.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049793223.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049810785.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049805553.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
XP_049789003.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049789936.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_049815532.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049789633.1	33	Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-69273;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-73776	"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Cyclin A/B1/B2 associated events during G2/M transition";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape"
XP_049806613.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049803211.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049807151.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049805439.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_049791298.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_049790356.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049794242.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049795791.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049792924.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049816567.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049812503.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049813913.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049811331.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049806127.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969	"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina"
XP_049791500.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_049808844.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049788777.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049797405.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049815147.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049794844.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049801974.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049801704.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049791430.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049816870.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049814290.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049807359.1	4	MetaCyc: PWY-8026;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72	"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis"
XP_049809123.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049794038.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_049791218.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049810366.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049805047.1	10	Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"RSK activation";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049793511.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049805250.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_049807851.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy"
XP_049806008.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049800921.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_049815266.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation"
XP_049806200.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-1489509	"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"Ion homeostasis";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"DAG and IP3 signaling"
XP_049810351.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049799710.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049801689.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049804997.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049797558.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-373080	"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Activation of SMO";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)"
XP_049789884.1	16	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-983168	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049793733.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049815564.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049793012.1	12	KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385	"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_049804488.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049815052.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049801214.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_049788559.1	5	Reactome: R-HSA-1234176;Reactome: R-HSA-1234174;Reactome: R-HSA-8849473;Reactome: R-HSA-8951664;Reactome: R-HSA-1234158	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cellular response to hypoxia";"PTK6 Expression";"Neddylation";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_049797451.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049815047.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801411.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049808716.1	5	Reactome: R-HSA-4755579;Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Androgen biosynthesis"
XP_049791004.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049789456.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049805149.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049795334.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049801039.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_049793103.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049816925.1	3	MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis"
XP_049813059.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049808491.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_049804615.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
XP_049811866.1	4	Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_049807486.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049804604.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812911.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813398.1	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_049788633.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049797412.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049791917.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_049808493.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049796203.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049806922.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049794102.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049791602.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049814207.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049811488.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049798809.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049811422.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110331	"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine"
XP_049791746.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049815512.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049790468.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049815583.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049798015.1	5	MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3	"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism"
XP_049792879.1	22	Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-389513	"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"RAF activation";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling"
XP_049806188.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049796640.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049808426.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049802781.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_049801379.1	1	Reactome: R-HSA-73943	"Reversal of alkylation damage by DNA dioxygenases"
XP_049811193.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049816622.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049815250.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049810051.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049790788.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049807904.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397	"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049804731.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049812419.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049806101.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049791050.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049791626.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049814161.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049788751.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049792090.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049813023.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049811826.1	13	KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-3841	"One carbon pool by folate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Folate transformations II (plants)"
XP_049804554.1	5	MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_049815477.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049801587.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049806264.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049793723.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049803570.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049807569.1	2	Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049795730.1	9	MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049804381.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049799376.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049789294.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049807480.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_049802081.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_049803388.1	4	MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049799104.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049789648.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049816348.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049807246.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-176187	"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress"
XP_049807656.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049804882.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049806496.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049789863.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049802232.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049815808.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049806222.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049815350.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_049811698.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_049810794.1	7	MetaCyc: PWY-3561;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148	"Choline biosynthesis III";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PG"
XP_049793702.1	12	MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683	"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Purine metabolism";"Selenocompound metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III"
XP_049809828.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049812473.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049806405.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-901032	"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
XP_049806246.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049801377.1	1	Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049794834.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049804733.1	19	Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938	"VLDL assembly";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Chylomicron assembly";"LDL clearance";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Chylomicron remodeling";"LDL remodeling";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand"
XP_049795660.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395	"Regulation of HSF1-mediated heat shock response";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER"
XP_049803801.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049811497.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049801716.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049804872.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049808820.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803477.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049804786.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357	"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling"
XP_049809817.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049789492.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049797581.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049789744.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049794714.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049812667.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049797473.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497	"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)"
XP_049813371.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540	"Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1"
XP_049807684.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049798334.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049804112.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_049799161.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_049801404.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049796249.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049790784.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049805788.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049808431.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049809364.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812431.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049794098.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049808542.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_049793668.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049802607.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_049808398.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_049791920.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049813699.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049813997.1	14	KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8052	"Ether lipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis"
XP_049803575.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049816787.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_049790834.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049794182.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049791524.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_049809257.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049798383.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049801536.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049810770.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049791429.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049792851.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049801785.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049797545.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049792996.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway"
XP_049816801.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049806427.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049811314.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049795418.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049813345.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049789423.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049805230.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049816292.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049791428.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049802300.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-6784531	"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus"
XP_049809486.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049811459.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661	"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation"
XP_049812794.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049804679.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049813441.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-9027277;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-2424491;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-2871796;Reactome: R-HSA-2029485	"FCERI mediated Ca+2 mobilization";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"DAP12 signaling";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated MAPK activation";"Role of phospholipids in phagocytosis"
XP_049804167.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-389960	"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049794156.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_049808418.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_049792103.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049802572.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049813304.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049811104.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_049800819.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049807796.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793660.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049797974.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862	"Signaling by EGFR";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049810107.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800405.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049812817.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791152.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049809229.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis"
XP_049806783.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049805832.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049792973.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049804719.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049807769.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803179.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_049810564.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049811496.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049804950.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_049793154.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_049794122.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049801754.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049814895.1	12	KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5857	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_049794019.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049807680.1	6	MetaCyc: PWY-5514;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049810657.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_049790686.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049813604.1	1	Reactome: R-HSA-6805567	"Keratinization"
XP_049815474.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_049802290.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049809791.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049809729.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049801075.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370	"Glutathione metabolism";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)"
XP_049802665.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049806117.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049808198.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049804568.1	6	Reactome: R-HSA-199220;Reactome: R-HSA-9640463;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765	"Vitamin B5 (pantothenate) metabolism";"Wax biosynthesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression"
XP_049815304.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049809391.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_049809315.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-6798695	"WNT ligand biogenesis and trafficking";"Neutrophil degranulation"
XP_049793201.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807853.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801664.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049811714.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049789696.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049810477.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049811716.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049806065.1	57	Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174178	"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Neddylation";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049810330.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049815822.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049789343.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049802779.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049790611.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049814269.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049800143.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049789708.1	18	KEGG: 00020+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-6783984;MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00620+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403;Reactome: R-HSA-5362517;Reactome: R-HSA-71064;KEGG: 00010+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-204174	"Citrate cycle (TCA cycle)";"Lysine degradation";"Propanoate metabolism";"Glycine, serine and threonine metabolism";"Glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Pyruvate metabolism";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"Signaling by Retinoic Acid";"Lysine catabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049802031.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_049805706.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049801514.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049807594.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-159231	"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049794180.1	4	KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_049805048.1	10	Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"RSK activation";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049807489.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049801742.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049798978.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049805725.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049790714.1	5	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_049800412.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049800799.1	58	Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5689901;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258	"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Metalloprotease DUBs";"Downstream TCR signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Degradation of DVL"
XP_049799472.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049791649.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176407	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049816379.1	4	MetaCyc: PWY-5028;MetaCyc: PWY-5030;KEGG: 00340+4.2.1.49;Reactome: R-HSA-70921	"L-histidine degradation II";"L-histidine degradation III";"Histidine metabolism";"Histidine catabolism"
XP_049793977.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814377.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049801510.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049789754.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049805936.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049813372.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763	"Nephrin family interactions";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction"
XP_049803488.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049793211.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792848.1	7	Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.28;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_049808365.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049807545.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049792637.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049810398.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049814851.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049789613.1	33	Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-191859	"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly"
XP_049802774.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049793217.1	25	Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"Gap junction assembly";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Kinesins"
XP_049805306.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049809694.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049814444.1	5	KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_049802930.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049789944.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_049789599.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049809293.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049799220.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049792140.1	11	KEGG: 04070+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-168138;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Phosphatidylinositol signaling system";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_049809831.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049799911.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40	"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Pyruvate metabolism"
XP_049808814.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808552.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049808099.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049790872.1	9	MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043	"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events"
XP_049805056.1	5	KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7	"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism"
XP_049790205.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049806410.1	7	KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system"
XP_049812487.1	12	Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840	"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Rho GTPase cycle"
XP_049809980.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-8049;MetaCyc: PWY-7746;MetaCyc: PWY-5971;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;MetaCyc: PWY-6799;Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-6113;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWY-5142;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-163765;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-6519	"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"Superpathway of mycolate biosynthesis";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I"
XP_049807072.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049808656.1	13	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049815105.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049808428.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049801675.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049791509.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049796246.1	12	Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049800438.1	11	MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7124	"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)"
XP_049795412.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_049813984.1	14	MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II"
XP_049804749.1	11	KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection"
XP_049792659.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049815858.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049800901.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049803779.1	18	MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7205	"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation"
XP_049812967.1	20	MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-5136	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049788672.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183	"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand"
XP_049790413.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049814758.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049803390.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_049809191.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049802924.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_049789589.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049798107.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_049810881.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049793789.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_049810289.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427359	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression"
XP_049805960.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049795448.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_049790062.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201	"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis"
XP_049800685.1	4	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation"
XP_049789596.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049807760.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812689.1	4	Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-196741;Reactome: R-HSA-3359463	"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_049788615.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049806155.1	4	KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9	"Starch and sucrose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_049788788.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049811633.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049801190.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049792700.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049812338.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049813914.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049813230.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049789082.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049788867.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049792638.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049809774.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806134.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049804470.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049799308.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049812871.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691	"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling"
XP_049799956.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_049799191.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049799165.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049791446.1	22	MetaCyc: PWY-7601;MetaCyc: PWY-7049;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-7726	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_049808135.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_049796250.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049804840.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049816899.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049801219.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049802709.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_049800539.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049811831.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049805270.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-2129379	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres"
XP_049815847.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049811561.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_049811319.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049813194.1	4	Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_049802816.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049815261.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049791518.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049803701.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_049812421.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049815612.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049798284.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804017.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049810335.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_049791906.1	4	MetaCyc: PWY-7849;MetaCyc: PWY-7394;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97	"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Purine metabolism"
XP_049801580.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049805530.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049805046.1	10	Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"RSK activation";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049815211.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049801279.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_049793382.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049793196.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049788820.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_049815906.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049811136.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_049793796.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049816690.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049811641.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049795524.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949	"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA"
XP_049793078.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049806887.1	27	Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358749;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-4641262;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5610785;Reactome: R-HSA-5250924;Reactome: R-HSA-8939902;Reactome: R-HSA-5358747;KEGG: 04151+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-198323;Reactome: R-HSA-5358752;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Human papillomavirus infection";"S37 mutants of beta-catenin aren't phosphorylated";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"GLI3 is processed to GLI3R by the proteasome";"B-WICH complex positively regulates rRNA expression";"Regulation of RUNX2 expression and activity";"S33 mutants of beta-catenin aren't phosphorylated";"PI3K-Akt signaling pathway";"CRMPs in Sema3A signaling";"AKT phosphorylates targets in the cytosol";"T41 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049793181.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816866.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049804744.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049810445.1	13	MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism"
XP_049789940.1	4	Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_049811548.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049803798.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17	"Pentose phosphate pathway";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation"
XP_049798811.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049808500.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049790813.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_049804256.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049804612.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049806446.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049811123.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-210746	"Regulation of gene expression in beta cells";"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"
XP_049795239.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049795948.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049807437.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049808840.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803584.1	5	KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074	"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Geraniol degradation";"Mevalonate degradation"
XP_049812942.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049790839.1	5	KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_049789947.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049792686.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049814251.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049805850.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049813876.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049808284.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049809623.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049792501.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049799794.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049814910.1	13	KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Human papillomavirus infection";"Human cytomegalovirus infection";"Sema4D induced cell migration and growth-cone collapse";"Relaxin signaling pathway";"mTOR signaling pathway";"RHO GTPases Activate ROCKs";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Thermogenesis"
XP_049790422.1	182	Reactome: R-HSA-5654733;Reactome: R-HSA-349425;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-69481;Reactome: R-HSA-937041;Reactome: R-HSA-9615710;Reactome: R-HSA-3134975;Reactome: R-HSA-192823;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-917729;Reactome: R-HSA-1169091;Reactome: R-HSA-5696395;Reactome: R-HSA-9604323;Reactome: R-HSA-6804760;Reactome: R-HSA-6804756;Reactome: R-HSA-9633012;Reactome: R-HSA-110320;Reactome: R-HSA-2672351;Reactome: R-HSA-3322077;Reactome: R-HSA-9014325;Reactome: R-HSA-5689901;Reactome: R-HSA-975957;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-5654727;Reactome: R-HSA-8852276;Reactome: R-HSA-8875360;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-168638;Reactome: R-HSA-72649;Reactome: R-HSA-69541;Reactome: R-HSA-5610783;Reactome: R-HSA-450302;Reactome: R-HSA-532668;Reactome: R-HSA-6807004;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-445989;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-6781827;Reactome: R-HSA-917937;Reactome: R-HSA-450321;Reactome: R-HSA-175474;Reactome: R-HSA-5656169;Reactome: R-HSA-936964;Reactome: R-HSA-5610785;Reactome: R-HSA-5675482;Reactome: R-HSA-5685942;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-168927;Reactome: R-HSA-382556;Reactome: R-HSA-2122947;Reactome: R-HSA-8863795;Reactome: R-HSA-936440;Reactome: R-HSA-72695;Reactome: R-HSA-3769402;Reactome: R-HSA-9013507;Reactome: R-HSA-5655862;Reactome: R-HSA-205043;Reactome: R-HSA-5693607;Reactome: R-HSA-2173796;Reactome: R-HSA-1236382;Reactome: R-HSA-8866652;Reactome: R-HSA-8939236;Reactome: R-HSA-2691232;Reactome: R-HSA-202424;Reactome: R-HSA-901032;Reactome: R-HSA-4641263;Reactome: R-HSA-6781823;Reactome: R-HSA-5654732;Reactome: R-HSA-2173795;Reactome: R-HSA-2467813;Reactome: R-HSA-168928;Reactome: R-HSA-3785653;Reactome: R-HSA-162588;Reactome: R-HSA-69231;Reactome: R-HSA-975163;Reactome: R-HSA-110312;Reactome: R-HSA-5358346;Reactome: R-HSA-2173788;Reactome: R-HSA-8866654;Reactome: R-HSA-156902;Reactome: R-HSA-5689877;Reactome: R-HSA-2979096;Reactome: R-HSA-2565942;Reactome: R-HSA-8941858;Reactome: R-HSA-5675221;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8948747;Reactome: R-HSA-2559582;Reactome: R-HSA-9645460;Reactome: R-HSA-5693565;Reactome: R-HSA-1253288;Reactome: R-HSA-2894862;Reactome: R-HSA-75815;Reactome: R-HSA-937072;Reactome: R-HSA-209560;Reactome: R-HSA-5689603;Reactome: R-HSA-975110;Reactome: R-HSA-174178;Reactome: R-HSA-1169408;Reactome: R-HSA-174490;Reactome: R-HSA-5676590;Reactome: R-HSA-9636383;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-5684264;Reactome: R-HSA-69601;Reactome: R-HSA-6804757;Reactome: R-HSA-8939902;Reactome: R-HSA-110314;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-5687128;Reactome: R-HSA-8856828;Reactome: R-HSA-1295596;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5357905;Reactome: R-HSA-6782135;Reactome: R-HSA-72702;Reactome: R-HSA-5654726;Reactome: R-HSA-5696397;Reactome: R-HSA-179409;Reactome: R-HSA-5696394;Reactome: R-HSA-174084;Reactome: R-HSA-201681;Reactome: R-HSA-5607761;Reactome: R-HSA-5689896;Reactome: R-HSA-9613829;Reactome: R-HSA-69017;Reactome: R-HSA-975144;Reactome: R-HSA-209543;Reactome: R-HSA-912631;Reactome: R-HSA-2408557;Reactome: R-HSA-8856825;Reactome: R-HSA-2122948;Reactome: R-HSA-5696400;Reactome: R-HSA-182971;Reactome: R-HSA-8876493;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-211733;Reactome: R-HSA-9637628;Reactome: R-HSA-5656121;Reactome: R-HSA-2173791;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-156827;Reactome: R-HSA-9033241;Reactome: R-HSA-5678895;Reactome: R-HSA-937039;Reactome: R-HSA-5205685;Reactome: R-HSA-9013973;Reactome: R-HSA-68827;Reactome: R-HSA-6783310;Reactome: R-HSA-5610780;Reactome: R-HSA-1358803;Reactome: R-HSA-9646399;Reactome: R-HSA-174048;Reactome: R-HSA-72706;Reactome: R-HSA-5607764;Reactome: R-HSA-6782210;Reactome: R-HSA-8849469	"Negative regulation of FGFR4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"G2/M Checkpoints";"IKK complex recruitment mediated by RIP1";"Late endosomal microautophagy";"Regulation of innate immune responses to cytosolic DNA";"Viral mRNA Translation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Activation of NF-kappaB in B cells";"Formation of Incision Complex in GG-NER";"Negative regulation of NOTCH4 signaling";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Activity through Phosphorylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translesion Synthesis by POLH";"Stimuli-sensing channels";"Glycogen synthesis";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Metalloprotease DUBs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Negative regulation of FGFR2 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"InlB-mediated entry of Listeria monocytogenes into host cell";"Neddylation";"Degradation of DVL";"NOD1/2 Signaling Pathway";"Translation initiation complex formation";"Stabilization of p53";"Degradation of GLI2 by the proteasome";"activated TAK1 mediates p38 MAPK activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of MET activity";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Iron uptake and transport";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Assembly Of The HIV Virion";"Termination of translesion DNA synthesis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"GLI3 is processed to GLI3R by the proteasome";"Regulation of necroptotic cell death";"HDR through Homologous Recombination (HRR)";"Vpu mediated degradation of CD4";"Circadian Clock";"TICAM1, RIP1-mediated IKK complex recruitment";"ABC-family proteins mediated transport";"NOTCH1 Intracellular Domain Regulates Transcription";"Downregulation of ERBB2 signaling";"Negative regulators of DDX58/IFIH1 signaling";"Formation of the ternary complex, and subsequently, the 43S complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Translesion synthesis by POLK";"NRIF signals cell death from the nucleus";"Processing of DNA double-strand break ends";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Downstream TCR signaling";"ER Quality Control Compartment (ERQC)";"Regulation of FZD by ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of FGFR3 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Separation of Sister Chromatids";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Myoclonic epilepsy of Lafora";"Budding and maturation of HIV virion";"Cyclin D associated events in G1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by REV1";"Hedgehog ligand biogenesis";"Downregulation of TGF-beta receptor signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Peptide chain elongation";"Josephin domain DUBs";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of RUNX3 expression and activity";"Negative regulation of MAPK pathway";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Regulation of PTEN localization";"Senescence-Associated Secretory Phenotype (SASP)";"Alpha-protein kinase 1 signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Downregulation of ERBB4 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Ubiquitin-dependent degradation of Cyclin D";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NF-kB is activated and signals survival";"UCH proteinases";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ISG15 antiviral mechanism";"Membrane binding and targetting of GAG proteins";"NIK-->noncanonical NF-kB signaling";"Prevention of phagosomal-lysosomal fusion";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Degradation";"Regulation of RUNX2 expression and activity";"Recognition of DNA damage by PCNA-containing replication complex";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"MAPK6/MAPK4 signaling";"Clathrin-mediated endocytosis";"Spry regulation of FGF signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of TNFR1 signaling";"Dual incision in TC-NER";"Ribosomal scanning and start codon recognition";"Negative regulation of FGFR1 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APC-Cdc20 mediated degradation of Nek2A";"DNA Damage Recognition in GG-NER";"Autodegradation of Cdh1 by Cdh1:APC/C";"TCF dependent signaling in response to WNT";"Dectin-1 mediated noncanonical NF-kB signaling";"Ovarian tumor domain proteases";"Chaperone Mediated Autophagy";"CDK-mediated phosphorylation and removal of Cdc6";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"p75NTR recruits signalling complexes";"Regulation of signaling by CBL";"Selenocysteine synthesis";"Cargo recognition for clathrin-mediated endocytosis";"Activated NOTCH1 Transmits Signal to the Nucleus";"Dual Incision in GG-NER";"EGFR downregulation";"InlA-mediated entry of Listeria monocytogenes into host cells";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Modulation by Mtb of host immune system";"Translesion synthesis by POLI";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peroxisomal protein import";"Defective CFTR causes cystic fibrosis";"IRAK1 recruits IKK complex";"Pink/Parkin Mediated Mitophagy";"TICAM1-dependent activation of IRF3/IRF7";"CDT1 association with the CDC6:ORC:origin complex";"Fanconi Anemia Pathway";"Degradation of GLI1 by the proteasome";"Downregulation of ERBB2:ERBB3 signaling";"Aggrephagy";"APC/C:Cdc20 mediated degradation of Cyclin B";"GTP hydrolysis and joining of the 60S ribosomal subunit";"CLEC7A (Dectin-1) signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"
XP_049808828.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049788786.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT"
XP_049802818.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049806591.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-114608	"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation"
XP_049805603.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049789943.1	4	KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049804086.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049804087.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049794188.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_049801284.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_049802802.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049801714.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049806270.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-159236	"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049809771.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049814948.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-606279	"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049801567.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049816798.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049805412.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049815914.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049804616.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
XP_049802399.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049798101.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049810768.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049811353.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049799217.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049816477.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049793776.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049797423.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049802712.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049810565.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049793213.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814375.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049802392.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049791913.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049806637.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049806196.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049791396.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_049810976.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"T cell receptor signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049802531.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049808913.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049816832.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_049805429.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049809622.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049790836.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049789381.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108	"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049807718.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049809908.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_049809742.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049803176.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence"
XP_049794968.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801644.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049806473.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_049802038.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049795444.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation"
XP_049805901.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049808636.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049808260.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_049790666.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_049807060.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049811660.1	8	KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1	"Galactose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis"
XP_049816016.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-73780;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-203927	"Formation of RNA Pol II elongation complex";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis"
XP_049791013.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049814038.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049789301.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049815405.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049812265.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049810426.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049793088.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049805964.1	12	MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1	"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Methane metabolism";"Lupulone and humulone biosynthesis";"Propanoate metabolism"
XP_049816879.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049804743.1	6	Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685	"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species"
XP_049795232.1	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049806282.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049809783.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049793537.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049814767.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_049805939.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049811828.1	13	MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III"
XP_049804067.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049792780.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_049814060.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049816233.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049813070.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049808056.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_049810793.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049816681.1	14	Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-174411	"Polymerase switching";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere"
XP_049806208.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049807530.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049811327.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049804977.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049816714.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049792050.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049814124.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808463.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049800991.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049813381.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809732.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049815196.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049799722.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049789379.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049814198.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049803838.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049802926.1	7	KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-174403;MetaCyc: PWY-6840;Reactome: R-HSA-5578999	"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_049811776.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049808694.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_049814496.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_049804122.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049809496.1	17	Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;MetaCyc: PWY-6627;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-6608	"Purine salvage";"Nicotinate and nicotinamide metabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Purine catabolism";"Guanosine nucleotides degradation III"
XP_049804085.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049809055.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049808259.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_049805229.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049790660.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049791585.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049791224.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049799045.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049808376.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049791564.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049793948.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049814705.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049790844.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049810362.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049816772.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_049792641.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049793260.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049805678.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049816799.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049806776.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049807162.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801577.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049808009.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049792651.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049810087.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049815674.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800818.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049810106.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049812002.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049810786.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049808792.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804705.1	5	MetaCyc: PWY-7766;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-5531	"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_049809975.1	2	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
XP_049795705.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_049809662.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049809621.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049790499.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815208.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049790493.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049813633.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049808556.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049789670.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049788979.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049793084.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049809136.1	31	MetaCyc: PWY-7388;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;Reactome: R-HSA-75105;MetaCyc: PWY-8047;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWYG-321;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-5973;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-6799;MetaCyc: PWY-5147;MetaCyc: PWY-8049;MetaCyc: PWY-7746;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971	"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_049798774.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049809730.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049792158.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049792537.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_049811874.1	8	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_049799603.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049812003.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049793374.1	6	Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Neddylation"
XP_049789132.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049805620.1	7	Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-381070	"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"IRE1alpha activates chaperones"
XP_049793619.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049811872.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049791747.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049789291.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049790961.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-190873	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation"
XP_049814285.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049805558.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049813962.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049799254.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049815121.1	7	Reactome: R-HSA-74217;MetaCyc: PWY-6610;MetaCyc: PWY-6605;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Purine salvage";"Adenine salvage";"Adenine and adenosine salvage II";"Neutrophil degranulation";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049799673.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049800742.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049811974.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049791454.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049805768.1	9	MetaCyc: PWY-5757;MetaCyc: PWY-6839;KEGG: 00440+4.1.1.82;MetaCyc: PWY-7769;MetaCyc: PWY-8067;MetaCyc: PWY-7510;KEGG: 00998+4.1.1.82;MetaCyc: PWY-6322;MetaCyc: PWY-6682	"Fosfomycin biosynthesis";"2-aminoethylphosphonate biosynthesis";"Phosphonate and phosphinate metabolism";"Phosalacine biosynthesis";"Methylphosphonate biosynthesis";"Rhizocticin A and B biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Phosphinothricin tripeptide biosynthesis";"Dehydrophos biosynthesis"
XP_049812928.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049792109.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049789261.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049808229.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049799918.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049800668.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_049810054.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049801111.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination"
XP_049805704.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049794181.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049809796.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049800879.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049814153.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049803440.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049805759.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_049814368.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex"
XP_049814293.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049803616.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-180534	"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4"
XP_049806970.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049813326.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049812423.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049800520.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_049808826.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049790709.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049806308.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829	"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049808676.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049789605.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049807764.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804482.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049803783.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049790667.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_049793197.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049794421.1	18	MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PE"
XP_049804728.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049788739.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049814240.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049816752.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049807216.1	13	MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18	"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes"
XP_049789716.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-165054	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA"
XP_049788805.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_049816075.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_049794378.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_049790680.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049808346.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049814925.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049809324.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049789219.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049816012.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors"
XP_049805538.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049805614.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049811340.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049806341.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049788982.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049794425.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049816087.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049792781.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176409	"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_049812691.1	4	Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011	"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance"
XP_049790408.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049814429.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Oxidative phosphorylation";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_049792270.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049789398.1	17	Reactome: R-HSA-75035;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-69601;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Relaxin signaling pathway";"G2/M DNA damage checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049815381.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049814885.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049793208.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049790270.1	12	KEGG: 00660+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-5744;MetaCyc: PWY-7295;MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-7294;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-6728	"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Glyoxylate assimilation";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"D-xylose degradation IV";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Methylaspartate cycle"
XP_049804603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801641.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-9609690	"Kinesins";"Recycling pathway of L1";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"HCMV Early Events"
XP_049801705.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049815191.1	11	KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184	"Purine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049803155.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049808958.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049804050.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049804672.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049809757.1	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_049803765.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049811973.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049809537.1	11	KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053	"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II"
XP_049799162.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_049807513.1	9	MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism"
XP_049801730.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049811346.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_049812380.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049797993.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049792162.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_049809228.1	4	Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781	"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis"
XP_049807152.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_049791161.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049792872.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049797116.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049790387.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049807989.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049793053.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049791464.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049789053.1	6	Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-69166	"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate"
XP_049795231.1	9	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049797744.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049796882.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049810178.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049793289.1	3	KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis"
XP_049803959.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-7559	"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway"
XP_049789338.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761	"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049801142.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049809888.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion"
XP_049793950.1	4	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription"
XP_049815200.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049815846.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049809670.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_049803232.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-5673001	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade"
XP_049811293.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_049802055.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049801755.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049805619.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-3371453	"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response"
XP_049802863.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049794793.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049792698.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049791593.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049806439.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_049798779.1	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
XP_049808075.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049801365.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049801698.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049816805.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_049790875.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049792673.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049809900.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis"
XP_049791718.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049800597.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049789883.1	10	Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-6527	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation"
XP_049808818.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049795257.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049789901.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-201722	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex"
XP_049815722.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049809604.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_049792528.1	6	Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Rho GTPase cycle"
XP_049809815.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_049808725.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049805743.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049799850.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_049802029.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049798190.1	11	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-8866654;Reactome: R-HSA-3270619;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA";"E3 ubiquitin ligases ubiquitinate target proteins";"IRF3-mediated induction of type I IFN";"Thermogenesis"
XP_049813822.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049794814.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_049797107.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049799940.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049798092.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049811754.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049809690.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_049807741.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049813221.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049798995.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
XP_049805320.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_049801702.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049814730.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049807529.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049810446.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049813896.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049811254.1	15	Reactome: R-HSA-9665233;Reactome: R-HSA-9665245;Reactome: R-HSA-9664565;Reactome: R-HSA-9665251;Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-8863795;Reactome: R-HSA-9665246;Reactome: R-HSA-9665250;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-5637810	"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by EGFRvIII"
XP_049798476.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049799927.1	7	MetaCyc: PWY-7219;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2	"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049797919.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049798304.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049796835.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049804720.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_049806523.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_049793077.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049804359.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049808303.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049791508.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049807930.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049802074.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_049812877.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_049803539.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049815496.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049804769.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049815353.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049802902.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049791753.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_049790181.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049797702.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049807029.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049816821.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049813057.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049801012.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049812615.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049795278.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049813581.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049811108.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049814695.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_049797911.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049810497.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049816730.1	1	Reactome: R-HSA-1234176	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049802537.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049814733.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049797981.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-7117	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_049809572.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049815866.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049805775.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049813113.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049814130.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049816707.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049788689.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049804312.1	20	Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049797868.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_049814431.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049788892.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049801353.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049808935.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049802846.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049808033.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049799345.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049796446.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_049797097.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-429947	"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA"
XP_049807939.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_049815223.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049806812.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497	"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Gap junction assembly";"HCMV Early Events";"Recycling pathway of L1";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049816911.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049789965.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_049811378.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049814250.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049792238.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049790801.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049810209.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049810978.1	18	MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115	"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049791297.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049808118.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049803698.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049789007.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049804504.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_049808347.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049793371.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PE"
XP_049801412.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049813450.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_049813457.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049807314.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049798267.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049816300.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_049804902.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049800813.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049812965.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049815708.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049808368.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049794314.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049811943.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049810621.1	17	KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-4202;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5695	"Nicotinate and nicotinamide metabolism";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Purine catabolism";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation"
XP_049803494.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9639288	"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1"
XP_049798269.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049808719.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049801591.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049811317.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049800360.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049813013.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049794018.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049801841.1	6	Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049789275.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049807768.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800845.1	11	KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6549;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42	"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Glutathione metabolism"
XP_049789830.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049816820.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_049789110.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049811728.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049800684.1	4	Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049790510.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049801366.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049812121.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049809635.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049811362.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049807983.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049810597.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049815807.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049808982.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049804848.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049810751.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049807798.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049797672.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049795462.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214	"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049808601.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049816614.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789100.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049807971.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization"
XP_049816662.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792237.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049800348.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049792743.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049795701.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049793738.1	17	KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780	"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Glyoxylate assimilation";"Propanoate metabolism";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Biotin transport and metabolism"
XP_049808281.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049799444.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049799115.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049792776.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_049812515.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808227.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_049807371.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049814752.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049804583.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049790512.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049811918.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805611.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049804313.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_049799242.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049802857.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_049813150.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA"
XP_049806304.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049814749.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049812289.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_049789217.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049795739.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049796243.1	12	Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-3214847	"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"HATs acetylate histones"
XP_049809216.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049794289.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_049805377.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049811192.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049814848.1	21	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7219;MetaCyc: PWY-7227;Reactome: R-HSA-499943	"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049811450.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049816757.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049805897.1	19	MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;Reactome: R-HSA-75105	"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis"
XP_049808001.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049816058.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049807568.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049794790.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049804629.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000471	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Retinoid metabolism and transport";"VLDL assembly";"Chylomicron clearance";"Scavenging by Class H Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class B Receptors"
XP_049797910.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049811219.1	5	Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_049793313.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_049802476.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049811696.1	52	Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_049796902.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764	"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling"
XP_049812646.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049806079.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049788877.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049805210.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049797980.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049793544.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049800730.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049816904.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049813147.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049807208.1	13	MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;Reactome: R-HSA-196836	"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism"
XP_049802638.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049789204.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049807761.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049789068.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049795805.1	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-3371511;Reactome: R-HSA-110312	"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"HSF1 activation";"Translesion synthesis by REV1"
XP_049804077.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049793942.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049814931.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049789476.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049797471.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)"
XP_049801732.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049791743.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049791463.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049790977.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049805618.1	7	Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-381033	"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones"
XP_049808817.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803480.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049796504.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258	"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Degradation of DVL"
XP_049814656.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049810462.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049788623.1	7	KEGG: 00970+6.1.1.15;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation"
XP_049803751.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049788691.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049807946.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049791158.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049811361.1	3	KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis"
XP_049793740.1	17	MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679	"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Jadomycin biosynthesis"
XP_049811634.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049807709.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585	"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence"
XP_049795151.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049801766.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_049810151.1	2	Reactome: R-HSA-192456;Reactome: R-HSA-975634	"Digestion of dietary lipid";"Retinoid metabolism and transport"
XP_049793198.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812442.1	13	Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-5099900	"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4"
XP_049814615.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049793288.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049803148.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_049812605.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling"
XP_049814815.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049788975.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049790505.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049814775.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049791448.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049813972.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4	"Plasmalogen biosynthesis";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_049794016.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5142;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-6113;MetaCyc: PWY-8012;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-5367	"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis"
XP_049789421.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049789679.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049816236.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049791700.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049802113.1	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
XP_049792917.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049804762.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript"
XP_049807679.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_049795624.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049801401.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_049806067.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049805638.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049804891.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049794796.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049816229.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_049814947.1	2	Reactome: R-HSA-606279;Reactome: R-HSA-6783310	"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway"
XP_049805673.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"HCMV Early Events";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins"
XP_049794288.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_049815769.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049791194.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049804357.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_049803516.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I"
XP_049792896.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049797115.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-450408	"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049791334.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049812792.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049791397.1	5	MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_049802217.1	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_049790883.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049816900.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049791274.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049810324.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049790504.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049808433.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7559	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway"
XP_049801209.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049805436.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_049794080.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049816891.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049816901.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049798096.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049800407.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049811569.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049812283.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport"
XP_049794972.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049810757.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806730.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049795911.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049810285.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049793903.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5632684	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state"
XP_049807614.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049793728.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049802125.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049815709.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049807975.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049792143.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Alanine racemization"
XP_049793185.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812812.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049791151.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049816051.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049805831.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049792144.1	4	MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040	"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis"
XP_049807186.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049812099.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049791535.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049797802.1	2	MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis"
XP_049793242.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049795719.1	16	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-201722	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex"
XP_049788883.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049789355.1	5	Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383	"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049808029.1	4	KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Selenocysteine synthesis"
XP_049815587.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049814518.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049804341.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049794037.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_049797421.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049791041.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459	"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049804589.1	4	MetaCyc: PWY-5030;MetaCyc: PWY-5028;KEGG: 00340+4.3.1.3;Reactome: R-HSA-70921	"L-histidine degradation III";"L-histidine degradation II";"Histidine metabolism";"Histidine catabolism"
XP_049792137.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049806184.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_049794907.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049814146.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049789976.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049791003.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049811547.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049805941.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049806206.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049808291.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion"
XP_049812962.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049791644.1	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049813298.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049801966.1	13	MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5	"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes"
XP_049812703.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_049816144.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049815195.1	11	KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism"
XP_049789373.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_049816853.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049789131.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049812929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049805747.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049801370.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_049810761.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807212.1	7	MetaCyc: PWY-7836;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_049791403.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049788555.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168333	"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049813414.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3	"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Glycerophospholipid metabolism"
XP_049805249.1	16	Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558	"G alpha (q) signalling events";"Interleukin-7 signaling";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Rho GTPase cycle";"Signaling by SCF-KIT";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"RET signaling";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_049790934.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049812353.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049788741.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049795868.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1"
XP_049789502.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049810333.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_049805233.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049793368.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049808547.1	29	Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6796648	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049796200.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049804859.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049805789.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049805612.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049815245.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_049811579.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_049814523.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049792188.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049812731.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049810401.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049791208.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792159.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049812785.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049814120.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807139.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049804457.1	10	Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764	"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling"
XP_049816208.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_049809751.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049803617.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_049805313.1	7	KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6121	"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049804862.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049808675.1	3	Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985	"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose"
XP_049803489.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049801678.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049798907.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049807102.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049797920.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049805527.1	10	MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-4041	"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle"
XP_049813168.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049810006.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049802464.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049812106.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049814457.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049800997.1	2	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049809218.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049809419.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049788548.1	7	KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61	"Citrate cycle (TCA cycle)";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism"
XP_049788832.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049805784.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049795652.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049808543.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_049802951.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807508.1	9	MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism"
XP_049806327.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049816878.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049813353.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Neutrophil degranulation"
YP_010401636.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049791549.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
XP_049794791.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_049806920.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049792107.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049800844.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049797737.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049802472.1	5	Reactome: R-HSA-416482;Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-446388	"G alpha (12/13) signalling events";"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"NRAGE signals death through JNK";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_049798196.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049801772.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049788784.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681	"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT"
XP_049789514.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049816218.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049811993.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049803619.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_049809907.1	6	MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709	"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins"
XP_049798979.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049813020.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813483.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049807615.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049793190.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809347.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049802058.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_049806108.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049814395.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_049815039.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049812512.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049793188.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808917.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049807511.1	9	KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18	"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450"
XP_049809333.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049800598.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049814999.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814122.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049794203.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049809535.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049815950.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049809943.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_049802034.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049799121.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049806767.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049792850.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049792950.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049794388.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049815770.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-918233	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway"
XP_049797388.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_049804542.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049790354.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049794178.1	4	MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism"
XP_049815804.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049793495.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049791580.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049803504.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049808668.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049814182.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049814841.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049816090.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049805800.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress"
XP_049805348.1	14	MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601	"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049808108.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049813337.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049792208.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049810434.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049795261.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049801210.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049808255.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049790020.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049805646.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049801159.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049803583.1	5	KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4	"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Geraniol degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies"
XP_049791101.1	14	KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5104;MetaCyc: PWY-5078;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5101;Reactome: R-HSA-70895;MetaCyc: PWY-7767;MetaCyc: PWY-5076	"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis IV";"L-isoleucine degradation II";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine biosynthesis";"L-valine degradation II";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"L-leucine degradation IV (Stickland reaction)";"L-leucine degradation III"
XP_049790507.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049799625.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049812813.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049790008.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159236	"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049788586.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049796510.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_049803467.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049814519.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049811109.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049813942.1	9	KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis"
XP_049808777.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049813453.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-6837	"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_049808555.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049800986.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049793311.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507	"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049797568.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049793430.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049802811.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049812427.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049801796.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049802666.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049792765.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049801373.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049793473.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049791395.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6	"Chitin degradation I (archaea)";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049805042.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049816906.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_049793957.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049805540.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122	"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Signal transduction by L1";"Neutrophil degranulation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049791136.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_049799093.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049810546.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049799219.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049803497.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-373080	"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO";"Class B/2 (Secretin family receptors)"
XP_049793615.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049808744.1	6	KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096	"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation"
XP_049796181.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049789989.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049804696.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049815907.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049794051.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049810503.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049789005.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_049809712.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814252.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049788589.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747	"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated"
XP_049802634.1	10	Reactome: R-HSA-5576893;Reactome: R-HSA-380284;Reactome: R-HSA-6802952;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5576890;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Phase 2 - plateau phase";"Loss of proteins required for interphase microtubule organization from the centrosome";"Signaling by BRAF and RAF fusions";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Phase 3 - rapid repolarisation";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049810229.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049793182.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049803712.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049807571.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049793973.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815721.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049792767.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049793700.1	12	KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25	"Purine metabolism";"Selenocompound metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Selenate reduction";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism"
XP_049793094.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049795534.1	14	MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7782	"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis"
XP_049809417.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_049812580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049793962.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
XP_049813484.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049805559.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049813415.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_049808241.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801670.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049813452.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6	"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism"
XP_049805197.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049794216.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049807625.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049803435.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049811989.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049807815.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049807543.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_049815801.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049810341.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049799944.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049812717.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049791102.1	14	MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-7767;MetaCyc: PWY-5101;MetaCyc: PWY-5076;Reactome: R-HSA-70895;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42	"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine biosynthesis";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"L-leucine degradation III";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"L-isoleucine degradation II";"Glucosinolate biosynthesis"
XP_049801405.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049794732.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049806344.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049798351.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049793344.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049792727.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049806189.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049814150.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049800621.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_049797881.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049800414.1	9	MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series"
XP_049808838.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791299.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049789118.1	5	KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_049814514.1	10	MetaCyc: PWY-6839;MetaCyc: PWY-7769;MetaCyc: PWY-5757;KEGG: 00440+5.4.2.9;MetaCyc: PWY-7510;MetaCyc: PWY-7419;MetaCyc: PWY-6322;MetaCyc: PWY-6682;KEGG: 00998+5.4.2.9;MetaCyc: PWY-8067	"2-aminoethylphosphonate biosynthesis";"Phosalacine biosynthesis";"Fosfomycin biosynthesis";"Phosphonate and phosphinate metabolism";"Rhizocticin A and B biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Dehydrophos biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Methylphosphonate biosynthesis"
XP_049810379.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049812969.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7337	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_049794280.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049816815.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049808603.1	29	Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-73863	"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination"
XP_049806699.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_049810710.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049809615.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049789600.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049790708.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049806513.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_049806145.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049812739.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049805309.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049809263.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049802608.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049815700.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049790302.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049792790.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049810464.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049812484.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049800825.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049795447.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1"
XP_049797021.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049797909.1	4	Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049804424.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049806493.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049792031.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_049812557.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049793706.1	12	MetaCyc: PWY-6683;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932	"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Selenocompound metabolism";"Purine metabolism";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenate reduction"
XP_049805627.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805621.1	9	Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097	"GPVI-mediated activation cascade";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway"
XP_049801632.1	6	Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citrate cycle (TCA cycle)"
XP_049815746.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049798977.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049809258.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049814892.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5870;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-6708	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_049815707.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049813455.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049809865.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-983168	"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049814773.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_049809096.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049804130.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049802840.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812267.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049802810.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049814468.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049800827.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049816018.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049814118.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808516.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049813192.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049793187.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811350.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination"
XP_049788554.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049789144.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049795153.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049811074.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049814698.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049792361.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049815481.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_049803395.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049798369.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049807763.1	8	MetaCyc: PWY-7400;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-4983	"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Canavanine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)"
XP_049804802.1	5	Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism"
XP_049815352.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049792952.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110357	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1"
XP_049799243.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049816363.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049793194.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049791494.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049807766.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807504.1	9	KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II"
XP_049811823.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049801954.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_049816725.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_049816243.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049810423.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans"
XP_049811245.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049802054.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049802032.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_049797470.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801179.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049789959.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049804703.1	5	MetaCyc: PWY-5531;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_049803890.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-5602680;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-5603037;Reactome: R-HSA-1236974;Reactome: R-HSA-3134963;Reactome: R-HSA-1810476;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-209543;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-5603041	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)";"ER-Phagosome pathway";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"RIP-mediated NFkB activation via ZBP1";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR2/4)"
XP_049805026.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049801790.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049808313.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805602.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049801402.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689	"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex"
XP_049791456.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis"
XP_049801020.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049796958.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049814660.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275	"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation"
XP_049800679.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049809661.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049809274.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049811792.1	17	Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids"
XP_049816132.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049805314.1	6	MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21	"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
XP_049815031.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049814512.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049791294.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049791443.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049813208.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049790711.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049804255.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049810417.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700	"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_049790992.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
XP_049801414.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049789942.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049806540.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-7238	"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II"
XP_049805000.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049810747.1	4	KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis"
XP_049806839.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049800676.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049791891.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049797382.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049815665.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049805550.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_049804580.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049789598.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049813193.1	4	Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_049795428.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049792797.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049807362.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049811160.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049789221.1	5	MetaCyc: PWY-7199;KEGG: 00240+2.7.1.21;KEGG: 00983+2.7.1.21;Reactome: R-HSA-69205;Reactome: R-HSA-73614	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"G1/S-Specific Transcription";"Pyrimidine salvage"
XP_049803667.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049806069.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049788800.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049800664.1	7	MetaCyc: PWY-3841;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;Reactome: R-HSA-196757;MetaCyc: PWY-6614	"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"One carbon pool by folate";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis"
XP_049801196.1	4	MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;MetaCyc: PWY-5188	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049796199.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049793737.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049808379.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049806263.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049801418.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049810007.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049807795.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049802746.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049799610.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049798242.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049793118.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049809022.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049789385.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807778.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049806742.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049809640.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811881.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833	"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly"
XP_049790089.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049792933.1	10	MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5844;MetaCyc: PWY-5892;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5895	"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis"
XP_049804985.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049797947.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049791423.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_049805307.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049806409.1	18	Reactome: R-HSA-6783984;KEGG: 00640+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00280+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00380+1.8.1.4;KEGG: 00620+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-70268	"Glycine degradation";"Propanoate metabolism";"Glycine, serine and threonine metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Lysine catabolism";"Pyruvate metabolism"
XP_049797450.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049791228.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049795201.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_049791392.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049806125.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049790951.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049790662.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049812740.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049807261.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_049793101.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049789372.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049791556.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049791855.1	5	MetaCyc: PWY-7181;KEGG: 00983+2.4.2.4;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.4;Reactome: R-HSA-73614	"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_049813015.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049789590.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049797715.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_049800627.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049807894.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049790342.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049800727.1	5	MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Purine metabolism"
YP_010401637.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049807345.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049788888.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049814577.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049816858.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049807040.1	10	MetaCyc: PWY-6535;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6537	"4-aminobutanoate degradation I";"Degradation of GABA";"Propanoate metabolism";"L-glutamate degradation IV";"Butanoate metabolism";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II"
XP_049801283.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_049812550.1	9	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049800962.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049788512.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049809097.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049795419.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049791153.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049793268.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_049811356.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination"
XP_049799439.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049808825.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049790870.1	9	MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043	"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events"
XP_049815771.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049816869.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049790950.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049806445.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049788798.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_049800665.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049804274.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801236.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049789231.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049790932.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_049791445.1	22	MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7606;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7049;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7727;Reactome: R-HSA-75876;MetaCyc: PWY-5353	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"
XP_049794704.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049789017.1	14	Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-500657;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-418217;KEGG: 00562+3.1.4.11;Reactome: R-HSA-4086398;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-112043	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G beta:gamma signalling through PLC beta";"Inositol phosphate metabolism";"Ca2+ pathway";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"PLC beta mediated events"
XP_049793359.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049791584.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049799224.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049811777.1	8	MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis"
XP_049800455.1	25	Reactome: R-HSA-8951936;Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-8931987;Reactome: R-HSA-8939242;Reactome: R-HSA-8878166;Reactome: R-HSA-8939256;Reactome: R-HSA-8949275;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8939245;Reactome: R-HSA-8939247;Reactome: R-HSA-8941284;Reactome: R-HSA-8941326;Reactome: R-HSA-8936459;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8939243;Reactome: R-HSA-8941333;Reactome: R-HSA-8951911;Reactome: R-HSA-8877330;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222	"RUNX3 regulates p14-ARF";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates bone development";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis"
XP_049792047.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049796508.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation"
XP_049796824.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049805987.1	16	KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5749;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.4	"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Itaconate degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism"
XP_049802123.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049799144.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049816845.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049789862.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049800767.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049790833.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049789097.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049813071.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049802488.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049806477.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049792260.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049790500.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801957.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049795200.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_049802540.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049802124.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049791766.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_049810003.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808810.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808780.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049790862.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791539.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049808831.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812721.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049812814.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049816204.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_049808677.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_049793812.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049794283.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793070.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049793098.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049793085.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049793358.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049806452.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049813788.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049811563.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049812579.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049792236.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049814445.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_049795226.1	5	Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111457	"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria"
XP_049793097.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049815100.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_049805779.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049810528.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049805938.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049794072.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049809299.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049789155.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_049796933.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049789233.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_049791040.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049808791.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049790189.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049807771.1	18	Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-1221632;MetaCyc: PWY-7511;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Meiotic synapsis";"Protein ubiquitination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6"
XP_049812909.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049814682.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049810239.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049812500.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049790727.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049806100.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049813473.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049791216.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049802953.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_049809091.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-180534	"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Neddylation";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4"
XP_049789977.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049807527.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049791931.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049794189.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_049794262.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049809196.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049798892.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812127.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812014.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049790038.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049798542.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_049812887.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049800218.1	10	MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_049808236.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049816190.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793497.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049808486.1	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049793453.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049810056.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049807931.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049808213.1	2	KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5	"Fructose and mannose metabolism";"Pentose and glucuronate interconversions"
XP_049793941.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049805021.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049792801.1	4	KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603	"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine"
XP_049789652.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049788823.1	6	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation"
XP_049813949.1	2	Reactome: R-HSA-210747;Reactome: R-HSA-210745	"Regulation of gene expression in early pancreatic precursor cells";"Regulation of gene expression in beta cells"
XP_049799221.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049794349.1	52	Reactome: R-HSA-167160;Reactome: R-HSA-73780;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-203927	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Chain Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis"
XP_049806372.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049808030.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_049807092.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs"
XP_049792252.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_049812053.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049814184.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049802291.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049805254.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049800995.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism"
XP_049793090.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049801438.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049801701.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049797488.1	4	Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_049804295.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle"
XP_049805007.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049806340.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_049805446.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049794800.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049811301.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049804890.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049813253.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049802075.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_049812387.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049814940.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049794041.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
XP_049788996.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_049811379.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_049805705.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049811668.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049802652.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049802396.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049806553.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049805555.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049795536.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8055	"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_049807301.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II"
XP_049806588.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049808761.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-5381;MetaCyc: PWY-6606	"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II"
XP_049813701.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049815183.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049803150.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049794801.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049802470.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049792908.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049802723.1	20	Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-165159;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972	"Macroautophagy";"Thermogenesis";"Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"mTOR signalling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049793186.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793935.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049792173.1	12	KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_049811326.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736	"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors"
XP_049805700.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-4641258;Reactome: R-HSA-201688	"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"Degradation of DVL";"WNT mediated activation of DVL"
XP_049812098.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049805898.1	19	MetaCyc: PWY-5392;Reactome: R-HSA-163765;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5537;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5	"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes"
XP_049815317.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049800781.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049800157.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049800917.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049800478.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Ether lipid metabolism"
XP_049805409.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049815173.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049802253.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_049804511.1	5	Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895	"Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism"
XP_049794912.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049812184.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049797883.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049812236.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206302	"HS-GAG degradation";"CS/DS degradation";"MPS I - Hurler syndrome"
XP_049808117.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049791946.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049793792.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049810764.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049792954.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-110362	"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair"
XP_049792916.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049801421.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049802466.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049789749.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049795474.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-156711	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events"
XP_049793826.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049816680.1	14	Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400	"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER"
XP_049792650.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049792214.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049815828.1	7	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends"
XP_049811972.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049801132.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049801244.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049810891.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049812982.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001	"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism"
XP_049810649.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049814452.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049793656.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049798016.1	5	Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3	"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine metabolism"
XP_049811810.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049800462.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049803513.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176409	"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_049795915.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049788521.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049795351.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751	"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity"
XP_049789434.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_049803833.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049789457.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy"
XP_049791568.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049813233.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049802414.1	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7221	"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis"
XP_049807298.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_049793552.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842	"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"HDMs demethylate histones"
XP_049790264.1	12	KEGG: 00620+2.3.3.9;MetaCyc: PWY-6969;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7294;MetaCyc: PWY-7854;MetaCyc: PWY-7118;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-6728;MetaCyc: PWY-5749;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5744;MetaCyc: PWY-7295	"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Itaconate degradation";"C5-Branched dibasic acid metabolism";"Glyoxylate assimilation";"L-arabinose degradation IV"
XP_049800812.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049812910.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049802708.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049801788.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049793370.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049814893.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_049801756.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049813306.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049812986.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049805345.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049813560.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049803918.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-180910	"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs"
XP_049797406.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049808760.1	11	MetaCyc: PWY-5381;MetaCyc: PWY-6606;MetaCyc: PWY-7185;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6607;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5	"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine metabolism"
XP_049809385.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049788809.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5358606	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049814023.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049815714.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553	"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Neddylation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs"
XP_049806590.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049809859.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)"
XP_049815977.1	13	MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049801246.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049793138.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809775.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049791923.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049801398.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_049810773.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049793282.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049813370.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753	"Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions"
XP_049811565.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049808276.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049814370.1	14	Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_049788727.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049816088.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049808553.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049791664.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049807871.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049802322.1	14	MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622	"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Glycine betaine degradation I";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Folate polyglutamylation";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)"
XP_049808077.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049791976.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049803796.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
XP_049814984.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049804660.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408	"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation"
XP_049816898.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049805176.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049812174.1	8	MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_049812107.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049808373.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049802140.1	7	KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-882	"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_049788922.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049812445.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049791756.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049792993.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1"
XP_049811302.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049809452.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049789636.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049807265.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049807901.1	5	Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939	"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)"
XP_049815645.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049793762.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049788868.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049811632.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049816052.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049805853.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049813698.1	11	MetaCyc: PWY-5154;Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7400;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049815580.1	7	Reactome: R-HSA-9018676;Reactome: R-HSA-9018681;Reactome: R-HSA-9023661;Reactome: R-HSA-6798695;Reactome: R-HSA-9018896;Reactome: R-HSA-9020265;Reactome: R-HSA-2142691	"Biosynthesis of D-series resolvins";"Biosynthesis of protectins";"Biosynthesis of E-series 18(R)-resolvins";"Neutrophil degranulation";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049789170.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049790288.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_049808729.1	16	MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-7124;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-7218;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11	"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism"
XP_049811631.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049802749.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049807891.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049801509.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049801397.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_049795238.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;MetaCyc: PWY-7980	"Ion channel transport";"Transferrin endocytosis and recycling";"Photosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ATP biosynthesis"
XP_049804724.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049800503.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049805622.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049809137.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
XP_049793443.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049789322.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049807743.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049816671.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049794261.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049793432.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049791641.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049793335.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807320.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049792895.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804853.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049798011.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049803709.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_049793555.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842	"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"HDMs demethylate histones"
XP_049804097.1	26	Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877	"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase"
XP_049789262.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796;Reactome: R-HSA-381426	"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049810353.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_049797729.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049794700.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049802199.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049793200.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816217.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049802534.1	3	MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049810098.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049807671.1	16	MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11	"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism"
XP_049790296.1	14	KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728	"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle"
XP_049788895.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049815479.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_049814903.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695	"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Neutrophil degranulation"
XP_049812415.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_049805304.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5981	"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III"
XP_049797627.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049793761.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049815831.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049802086.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7177	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II"
XP_049793536.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049791056.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049800291.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656237	"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2"
XP_049810557.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049791073.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041	"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_049810648.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049799711.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049804839.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049814172.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049804610.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049795262.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-68949	"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin"
XP_049793355.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049802610.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049793081.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049807485.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049813917.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049808869.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425	"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049802576.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049814681.1	13	Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725	"Aggrephagy";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"HSF1 activation";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation"
XP_049788564.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049810899.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049802533.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049814379.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_049791074.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049806475.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049806210.1	6	MetaCyc: PWY-5789;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5743	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate cycle"
XP_049816086.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_049789099.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049801204.1	30	Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-2564830;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"mRNA Capping";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Cytosolic iron-sulfur cluster assembly";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_049792782.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049793115.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049793665.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I"
XP_049809083.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049815666.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049812818.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049799522.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049805492.1	7	MetaCyc: PWY-7221;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695	"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine 5'-phosphate degradation"
XP_049815017.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69601	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_049810592.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_049811385.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049809330.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049797717.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049816396.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049798135.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049806476.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049801727.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049806195.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049811456.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049790508.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049810835.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049809607.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_049794850.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2"
XP_049807453.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_049800406.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049792543.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049814309.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049791916.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase"
XP_049789033.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049809403.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049814899.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_049788785.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT"
XP_049812586.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812454.1	5	Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-381038	"Hedgehog ligand biogenesis";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes"
XP_049794583.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049807414.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-204626;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Hypusine synthesis from eIF5A-lysine";"Th1 and Th2 cell differentiation"
XP_049811256.1	15	Reactome: R-HSA-5637810;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-9665250;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665244;Reactome: R-HSA-9665245;Reactome: R-HSA-9665233;Reactome: R-HSA-9664565;Reactome: R-HSA-9652282;Reactome: R-HSA-9665251	"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to AEE788";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2 KD Mutants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib"
XP_049789710.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049793281.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049791202.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049804090.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049790803.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_049795539.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049788825.1	6	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Galactose metabolism"
XP_049805010.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049806722.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049808279.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049795724.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation"
XP_049800602.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049788918.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049806129.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_049803200.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049788866.1	14	KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6538;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4;KEGG: 00983+1.17.3.2;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6596	"Purine metabolism";"Theophylline degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Drug metabolism - other enzymes";"Caffeine metabolism";"Adenosine nucleotides degradation I"
XP_049789422.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049816742.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049790980.1	5	Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662	"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling"
XP_049793974.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049788875.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049816850.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049789544.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049804842.1	3	MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway"
XP_049789083.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049799611.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049811315.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049813012.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049812179.1	8	MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_049798310.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049809325.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049810632.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174184	"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Neddylation";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_049800687.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049804996.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049816227.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049808357.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049793664.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049812497.1	4	Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049810678.1	24	Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;KEGG: 05163+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5674400;Reactome: R-HSA-2730905;Reactome: R-HSA-5625740;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764	"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"mTOR signaling pathway";"GPVI-mediated activation cascade";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"RSK activation";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"Human cytomegalovirus infection";"Integrin signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Role of LAT2/NTAL/LAB on calcium mobilization";"RHO GTPases activate PKNs";"Human papillomavirus infection";"FCERI mediated NF-kB activation";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling"
XP_049812648.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049807902.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049805473.1	14	MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_049801413.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049802748.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049803182.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049794201.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049790765.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049811190.1	11	MetaCyc: PWY-3861;Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-5659	"Mannitol degradation II";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis"
XP_049789880.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049799056.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049811984.1	6	KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346	"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_049803657.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724	"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Regulation of PTEN gene transcription"
XP_049812583.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049802645.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_049805758.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049815342.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049790018.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049802538.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049791741.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049800410.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049789975.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049793662.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049809633.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049803170.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049792105.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049793307.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049793628.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049799949.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049793117.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049790102.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049814943.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049805375.1	6	MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway"
XP_049807609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049806407.1	18	MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-5362517;KEGG: 00010+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-204174;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403	"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Propanoate metabolism";"Glycine, serine and threonine metabolism";"Glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Pyruvate metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)"
XP_049800170.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049811478.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_049798100.1	4	MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism"
XP_049809223.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049811490.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049812651.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049807109.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049790778.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049805707.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049794559.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049789228.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049808423.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_049802575.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049805238.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-202433	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules"
XP_049809285.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049791292.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049792877.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049805041.1	10	KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11+1.2.1.41	"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_049789234.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049812688.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049807997.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049811940.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049816205.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_049810275.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049810086.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_049798105.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049789420.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049809904.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis"
XP_049793915.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049809841.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049801569.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049790323.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049810161.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049797655.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_049811988.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049791765.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049804108.1	40	KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7216;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6944;KEGG: 00360+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5136;MetaCyc: PWY-7779;MetaCyc: PWY-7726;MetaCyc: PWY-6945;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7656;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-5138;MetaCyc: PWY-7401	"Caprolactam degradation";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Geraniol degradation";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Glutaryl-coa degradation";"Toluene degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Androstenedione degradation";"Phenylalanine metabolism";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Spodoptera littoralis pheromone biosynthesis";"Benzoate degradation";"Fatty acid salvage";"Propanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)"
XP_049815767.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049789104.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049803531.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_049799709.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049803672.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049815079.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049807510.1	9	MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18	"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione metabolism"
XP_049810204.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049792039.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049810815.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049793284.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049802045.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049810919.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049801744.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049808834.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049795280.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049811494.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049794447.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804215.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049794241.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049801407.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049802983.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_049806137.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049812178.1	8	MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049814822.1	13	Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;MetaCyc: PWY-7883	"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II"
XP_049811403.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049801700.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049789671.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049814871.1	33	Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-191859	"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly"
XP_049805252.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis"
XP_049793060.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049790889.1	18	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049812948.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049795728.1	9	KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_049794860.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049802044.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049814197.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049805286.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049811259.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049809830.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049813413.1	6	MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166	"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA"
XP_049800681.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049805236.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049804767.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049791650.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_049790641.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7574	"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II"
XP_049809998.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049810718.1	12	Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6811436	"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049788753.1	10	KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_049815366.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1362277	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049789516.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049798908.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049803177.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors"
XP_049790878.1	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049808808.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049809933.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049805946.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174154	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin"
XP_049805147.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049802743.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049788889.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_049808468.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049804329.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049806760.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049790640.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858	"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II"
XP_049788796.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049811868.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-532668	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049793989.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049805136.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049807570.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049801753.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049816659.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792362.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049796590.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049810070.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049805992.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049799965.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049815922.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049816682.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049803905.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Ub-specific processing proteases"
XP_049797755.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049804707.1	5	MetaCyc: PWY-5531;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_049790470.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049789388.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-197264	"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Nicotinamide salvaging"
XP_049809328.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049806011.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_049812675.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049806778.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049807322.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049789344.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049806126.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_049807633.1	10	KEGG: 05165+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"3-phosphoinositide biosynthesis"
XP_049812697.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049802504.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049789242.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_049798960.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049788954.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049797912.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049794113.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049805467.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049789776.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049788574.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049814107.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049810198.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049815705.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049811937.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_049808872.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_049809840.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049807665.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049813384.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Neutrophil degranulation";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049811985.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate"
XP_049809478.1	18	MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383	"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049794390.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049804702.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049803669.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049788635.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049813289.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049800826.1	4	KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642	"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation"
XP_049801844.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049803010.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049814632.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5	"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes"
XP_049789532.1	6	KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-6737	"Starch and sucrose metabolism";"Glycogen degradation II";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Starch degradation V"
XP_049789390.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049802971.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049809864.1	5	Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-983168	"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049812695.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049807474.1	10	Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Other glycan degradation"
XP_049802065.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049797414.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049814960.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049807292.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_049809778.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049789592.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation"
XP_049814751.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049801653.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049793429.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049803851.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049803527.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049809120.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049812786.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049799955.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049814559.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049813294.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049810336.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049794340.1	7	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22	"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_049793649.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049793119.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049794093.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049795263.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049813820.1	8	MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_049810676.1	24	Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-5218921;Reactome: R-HSA-165158;Reactome: R-HSA-2871837;Reactome: R-HSA-5674400;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1	"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated cell proliferation";"Activation of AKT2";"FCERI mediated NF-kB activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Integrin signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"RSK activation";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway"
XP_049816658.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049796956.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049800466.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411	"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere"
XP_049789054.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-162594	"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle"
XP_049814488.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955	"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Ion homeostasis";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049803476.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049808911.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049791517.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049788981.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049816728.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049812164.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049803744.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049815710.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049807585.1	7	MetaCyc: PWY-5698;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-5697;MetaCyc: PWY-7790;KEGG: 00230+3.5.2.5	"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis II";"Purine metabolism"
XP_049803192.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049800992.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_049789366.1	5	Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381	"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)"
XP_049806342.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049800404.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049812987.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049812491.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049805963.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049812637.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049790285.1	1	Reactome: R-HSA-193670	"p75NTR negatively regulates cell cycle via SC1"
XP_049810527.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_049792091.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049788655.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049789143.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049806858.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049808487.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049804611.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049810408.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049791819.1	12	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Rho GTPase cycle";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Thermogenesis"
XP_049789657.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049802735.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-180910	"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear import of Rev protein";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs"
XP_049802897.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049801634.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049791755.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049799527.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049795445.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049794736.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049815500.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049790766.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049812039.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049800480.1	11	Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-72163;Reactome: R-HSA-2173796	"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"mRNA Splicing - Major Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_049810381.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681	"Protein ubiquitination";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT"
XP_049814929.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049813072.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049801166.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049804514.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_049800468.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_049802769.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_049795154.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_049816761.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049802644.1	4	KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817	"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_049806178.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049806556.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_049807676.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_049805549.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_049801707.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049814221.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049810057.1	5	MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_049808584.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_049795717.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586	"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence"
XP_049808734.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811663.1	8	KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1	"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Streptomycin biosynthesis"
XP_049803050.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049815044.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049814043.1	5	KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983	"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)"
XP_049791182.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_049801539.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049813634.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049810420.1	33	Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464	"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins"
XP_049815680.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049800018.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049807889.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049806917.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049791921.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049803468.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049796182.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049804071.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340	"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_049797884.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049790471.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049801424.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_049792984.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-8060;Reactome: R-HSA-71336;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4	"Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway"
XP_049801188.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_049804544.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049800680.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049790739.1	16	Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-167238	"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049803051.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049792649.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049794158.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049788783.1	180	Reactome: R-HSA-8939236;Reactome: R-HSA-8866652;Reactome: R-HSA-2173796;Reactome: R-HSA-1236382;Reactome: R-HSA-205043;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-9013507;Reactome: R-HSA-3769402;Reactome: R-HSA-936440;Reactome: R-HSA-8863795;Reactome: R-HSA-2122947;Reactome: R-HSA-382556;Reactome: R-HSA-168927;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-5685942;Reactome: R-HSA-5675482;Reactome: R-HSA-5610785;Reactome: R-HSA-936964;Reactome: R-HSA-5656169;Reactome: R-HSA-175474;Reactome: R-HSA-2173789;Reactome: R-HSA-450321;Reactome: R-HSA-917937;Reactome: R-HSA-5675221;Reactome: R-HSA-8941858;Reactome: R-HSA-2565942;Reactome: R-HSA-2979096;Reactome: R-HSA-5689877;Reactome: R-HSA-156902;Reactome: R-HSA-8866654;Reactome: R-HSA-2173788;Reactome: R-HSA-5358346;Reactome: R-HSA-110312;Reactome: R-HSA-975163;Reactome: R-HSA-69231;Reactome: R-HSA-162588;Reactome: R-HSA-3785653;Reactome: R-HSA-168928;Reactome: R-HSA-2467813;Reactome: R-HSA-2173795;Reactome: R-HSA-5654732;Reactome: R-HSA-6781823;Reactome: R-HSA-4641263;Reactome: R-HSA-901032;Reactome: R-HSA-202424;Reactome: R-HSA-2691232;Reactome: R-HSA-110320;Reactome: R-HSA-9633012;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-9604323;Reactome: R-HSA-5696395;Reactome: R-HSA-1169091;Reactome: R-HSA-917729;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-192823;Reactome: R-HSA-3134975;Reactome: R-HSA-9615710;Reactome: R-HSA-937041;Reactome: R-HSA-69481;Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-349425;Reactome: R-HSA-5654733;Reactome: R-HSA-6781827;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-6807004;Reactome: R-HSA-450302;Reactome: R-HSA-532668;Reactome: R-HSA-5610783;Reactome: R-HSA-69541;Reactome: R-HSA-168638;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-8875360;Reactome: R-HSA-8852276;Reactome: R-HSA-5654727;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-975957;Reactome: R-HSA-5689901;Reactome: R-HSA-9014325;Reactome: R-HSA-3322077;Reactome: R-HSA-2672351;Reactome: R-HSA-2173791;Reactome: R-HSA-5656121;Reactome: R-HSA-9637628;Reactome: R-HSA-975956;Reactome: R-HSA-211733;Reactome: R-HSA-72764;Reactome: R-HSA-450408;Reactome: R-HSA-1799339;Reactome: R-HSA-8876493;Reactome: R-HSA-182971;Reactome: R-HSA-5696400;Reactome: R-HSA-2122948;Reactome: R-HSA-8856825;Reactome: R-HSA-2408557;Reactome: R-HSA-912631;Reactome: R-HSA-209543;Reactome: R-HSA-975144;Reactome: R-HSA-69017;Reactome: R-HSA-5689896;Reactome: R-HSA-9613829;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-201681;Reactome: R-HSA-5696394;Reactome: R-HSA-179409;Reactome: R-HSA-5696397;Reactome: R-HSA-8849469;Reactome: R-HSA-6782210;Reactome: R-HSA-5607764;Reactome: R-HSA-72706;Reactome: R-HSA-174048;Reactome: R-HSA-1358803;Reactome: R-HSA-6783310;Reactome: R-HSA-5610780;Reactome: R-HSA-9646399;Reactome: R-HSA-68827;Reactome: R-HSA-9013973;Reactome: R-HSA-937039;Reactome: R-HSA-5205685;Reactome: R-HSA-5678895;Reactome: R-HSA-9033241;Reactome: R-HSA-156827;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-977225;Reactome: R-HSA-9636383;Reactome: R-HSA-5676590;Reactome: R-HSA-174490;Reactome: R-HSA-1169408;Reactome: R-HSA-174178;Reactome: R-HSA-975110;Reactome: R-HSA-209560;Reactome: R-HSA-5689603;Reactome: R-HSA-937072;Reactome: R-HSA-75815;Reactome: R-HSA-2894862;Reactome: R-HSA-2559582;Reactome: R-HSA-1253288;Reactome: R-HSA-9645460;Reactome: R-HSA-5693565;Reactome: R-HSA-8948747;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5654726;Reactome: R-HSA-6782135;Reactome: R-HSA-5357905;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-8856828;Reactome: R-HSA-1295596;Reactome: R-HSA-5687128;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-110314;Reactome: R-HSA-8939902;Reactome: R-HSA-6804757;Reactome: R-HSA-69601;Reactome: R-HSA-5684264;Reactome: R-HSA-2644606	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NRIF signals cell death from the nucleus";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Deactivation of the beta-catenin transactivating complex";"Negative regulators of DDX58/IFIH1 signaling";"Downregulation of ERBB2 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"ABC-family proteins mediated transport";"TICAM1, RIP1-mediated IKK complex recruitment";"Vpu mediated degradation of CD4";"Circadian Clock";"HDR through Homologous Recombination (HRR)";"Regulation of necroptotic cell death";"GLI3 is processed to GLI3R by the proteasome";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Termination of translesion DNA synthesis";"Assembly Of The HIV Virion";"TGF-beta receptor signaling activates SMADs";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Iron uptake and transport";"Negative regulation of MAPK pathway";"Regulation of RUNX3 expression and activity";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Josephin domain DUBs";"Peptide chain elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Downregulation of TGF-beta receptor signaling";"Hedgehog ligand biogenesis";"Translesion synthesis by REV1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Cyclin D associated events in G1";"Budding and maturation of HIV virion";"Myoclonic epilepsy of Lafora";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Separation of Sister Chromatids";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Negative regulation of FGFR3 signaling";"Formation of TC-NER Pre-Incision Complex";"Regulation of FZD by ubiquitination";"ER Quality Control Compartment (ERQC)";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Translesion Synthesis by POLH";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Negative regulation of NOTCH4 signaling";"Formation of Incision Complex in GG-NER";"Activation of NF-kappaB in B cells";"Endosomal Sorting Complex Required For Transport (ESCRT)";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Viral mRNA Translation";"Regulation of innate immune responses to cytosolic DNA";"Late endosomal microautophagy";"IKK complex recruitment mediated by RIP1";"G2/M Checkpoints";"IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of FGFR4 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Negative regulation of MET activity";"activated TAK1 mediates p38 MAPK activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of GLI2 by the proteasome";"Stabilization of p53";"NOD1/2 Signaling Pathway";"Degradation of DVL";"Neddylation";"InlB-mediated entry of Listeria monocytogenes into host cell";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR2 signaling";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Metalloprotease DUBs";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Glycogen synthesis";"Stimuli-sensing channels";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Translesion synthesis by POLI";"Modulation by Mtb of host immune system";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Eukaryotic Translation Termination";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SRP-dependent cotranslational protein targeting to membrane";"InlA-mediated entry of Listeria monocytogenes into host cells";"EGFR downregulation";"Dual Incision in GG-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"Cargo recognition for clathrin-mediated endocytosis";"Selenocysteine synthesis";"Regulation of signaling by CBL";"p75NTR recruits signalling complexes";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"CDK-mediated phosphorylation and removal of Cdc6";"Ovarian tumor domain proteases";"Chaperone Mediated Autophagy";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TCF dependent signaling in response to WNT";"DNA Damage Recognition in GG-NER";"APC-Cdc20 mediated degradation of Nek2A";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"CLEC7A (Dectin-1) signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"APC/C:Cdc20 mediated degradation of Cyclin B";"Downregulation of ERBB2:ERBB3 signaling";"Fanconi Anemia Pathway";"Degradation of GLI1 by the proteasome";"Aggrephagy";"CDT1 association with the CDC6:ORC:origin complex";"TICAM1-dependent activation of IRF3/IRF7";"IRAK1 recruits IKK complex";"Pink/Parkin Mediated Mitophagy";"Defective CFTR causes cystic fibrosis";"Peroxisomal protein import";"L13a-mediated translational silencing of Ceruloplasmin expression";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Amyloid fiber formation";"Prevention of phagosomal-lysosomal fusion";"NIK-->noncanonical NF-kB signaling";"Membrane binding and targetting of GAG proteins";"ISG15 antiviral mechanism";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"NF-kB is activated and signals survival";"UCH proteinases";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Senescence-Associated Secretory Phenotype (SASP)";"Downregulation of ERBB4 signaling";"Alpha-protein kinase 1 signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of PTEN localization";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR1 signaling";"Dual incision in TC-NER";"Regulation of TNFR1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Clathrin-mediated endocytosis";"Spry regulation of FGF signaling";"MAPK6/MAPK4 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of RUNX2 expression and activity";"Regulation of TP53 Degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049791032.1	6	MetaCyc: PWY-7077;MetaCyc: PWY-7395;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25	"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049801378.1	1	Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049791431.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049815262.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049788758.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium"
XP_049804855.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049810004.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049800988.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049805557.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049802630.1	9	MetaCyc: PWY-7003;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-8004;Reactome: R-HSA-70171	"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycolysis"
XP_049793743.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049789731.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049809619.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049802704.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049805699.1	7	Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-201681	"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Degradation of DVL";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT"
XP_049797772.1	4	Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049806555.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049810228.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049808040.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049790892.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049806495.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049816184.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049811296.1	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437	"HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation"
XP_049794209.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805869.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049813467.1	6	Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_049789004.1	57	Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Degradation of DVL";"Defective CFTR causes cystic fibrosis"
XP_049804852.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049805420.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049810283.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049803726.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049809233.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049801081.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049792657.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049802120.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049808277.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049801000.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049808874.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049805905.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049805156.1	7	KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3	"One carbon pool by folate";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_049789216.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049805301.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_049805160.1	5	KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3	"One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Folate biosynthesis"
XP_049808496.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049807572.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049808305.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049807942.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049801428.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049810395.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049808525.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_049809571.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049811883.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436	"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Gap junction assembly";"HCMV Early Events";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049809581.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049806487.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805900.1	19	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-5537;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5392	"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Reductive TCA cycle II"
XP_049808891.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812367.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049795170.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049801846.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049799523.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049801786.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049793369.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049801544.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049810922.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807391.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049812475.1	10	Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;MetaCyc: PWY-7849;Reactome: R-HSA-977225;MetaCyc: PWY-7394;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17	"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Urate conversion to allantoin III";"Amyloid fiber formation";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Purine metabolism"
XP_049803487.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049800605.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation";"Macroautophagy"
XP_049797916.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049807136.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049795137.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049808606.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049793202.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049794426.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_049792884.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049811628.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049807849.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049799931.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049799141.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049815918.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049792642.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049815046.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812229.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-350562	"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)"
XP_049803602.1	6	MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907	"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)"
XP_049815149.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049811423.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine"
XP_049790726.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049801227.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049793834.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049803515.1	5	MetaCyc: PWY-5668;MetaCyc: PWY-7817;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5	"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Synthesis of PG";"Glycerophospholipid metabolism"
XP_049799772.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049793633.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049800862.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049811303.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049792899.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RAF activation";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_049801998.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049808898.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing"
XP_049802076.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049814900.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049805749.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049812077.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049808419.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_049811953.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049792092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049788588.1	8	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Synthesis of PG"
XP_049810873.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049814301.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049809494.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049802770.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
YP_010401639.1	7	MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;MetaCyc: PWY-3781;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2	"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Fe(II) oxidation";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation"
XP_049814469.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049810767.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049806003.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049810650.1	18	MetaCyc: PWY-6638;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1	"Sulfolactate degradation III";"(R)-cysteate degradation";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"Arginine biosynthesis";"Cysteine and methionine metabolism"
XP_049811986.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049793048.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049788914.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9648895;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049807350.1	5	Reactome: R-HSA-9627069;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome"
XP_049800025.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049793007.1	12	KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5484;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis"
XP_049804888.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049790164.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049813203.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049802204.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049802839.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813404.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049793134.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806755.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049789693.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049816797.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049791346.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049808295.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049810337.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049789591.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_049816727.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049804836.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168325	"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis"
XP_049807547.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-1592389	"Collagen degradation";"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases"
XP_049809923.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802296.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049802430.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049802809.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049801041.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049797580.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049810975.1	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"T cell receptor signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049801191.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049812414.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049802480.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049793763.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049796375.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049788884.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_049809849.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-180024	"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"DARPP-32 events"
XP_049792717.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049815478.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049795158.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_049791295.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049803178.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway"
XP_049815203.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049794131.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049804089.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049802000.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049811250.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049797283.1	19	Reactome: R-HSA-418885;Reactome: R-HSA-5663220;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-5626467;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-5625970;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-194840	"DCC mediated attractive signaling";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"RHO GTPases activate IQGAPs";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"RHO GTPases activate KTN1";"EGFR downregulation";"MAPK6/MAPK4 signaling";"Rho GTPase cycle"
XP_049791067.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049804536.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049811377.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049803614.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049801972.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049811268.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049801655.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049811734.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049801391.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049802194.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049815311.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049791971.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_049799756.1	25	Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"Gap junction assembly";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Kinesins"
XP_049805165.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_049790615.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049806650.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_049801211.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049810399.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049800439.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049797774.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049805969.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049814995.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049793718.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049792304.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049801433.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049790874.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049792890.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5467340	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"RAF activation";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex"
XP_049816191.1	13	MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation"
XP_049805066.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049807532.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049812899.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049805057.1	5	MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis"
XP_049808845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049808206.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049809792.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049816395.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049794792.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049805008.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049809901.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis"
XP_049791720.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049793255.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049815490.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049811062.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049815214.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049794215.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049803784.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049805637.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049815628.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049812337.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049809087.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_049816011.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria"
XP_049815805.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049805740.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049814121.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049798314.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049790492.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049789718.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049812388.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049802604.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049812204.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049793510.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049791680.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049795952.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049799816.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049808822.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049816683.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_049802024.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation"
XP_049812508.1	7	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Thiamine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049805272.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049806641.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049810789.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049793271.1	6	KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_049788882.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049808671.1	29	Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-3371511;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"HSF1 activation";"Translesion synthesis by REV1";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER"
XP_049792192.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049800889.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049799719.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-1042	"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)"
XP_049815535.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049816800.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049806243.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation"
XP_049793590.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049793156.1	6	Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"HCMV Early Events";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049800362.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809259.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793944.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049793072.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_049799521.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049812022.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049804046.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049810765.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049810750.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049808160.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049802057.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049805744.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049811167.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049811960.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049808158.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049803990.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001	"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_049800669.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_049798023.1	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049795659.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858	"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Neddylation";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity"
XP_049816679.1	14	Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400	"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER"
XP_049807473.1	10	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049802755.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049810282.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049810716.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049788854.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049812040.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049803436.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049799215.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049790981.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049807664.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049802292.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_049793080.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049788533.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049793124.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049814442.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049802391.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049801171.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049789992.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049807255.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453	"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis"
XP_049803172.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14	"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_049816670.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049795379.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049802823.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049812673.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553	"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs"
XP_049804236.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952	"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation"
XP_049793991.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism"
XP_049795286.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049815675.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049804968.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049789460.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049789324.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049794826.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049815000.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815720.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049790547.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049789466.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Lipophagy"
XP_049809505.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049797427.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049790257.1	12	MetaCyc: PWY-7295;MetaCyc: PWY-5744;MetaCyc: PWY-5749;KEGG: 00660+4.1.3.25;MetaCyc: PWY-6728;MetaCyc: PWY-7118;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7854;KEGG: 00720+4.1.3.25;MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9	"L-arabinose degradation IV";"Glyoxylate assimilation";"Itaconate degradation";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism"
XP_049811341.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-1268020	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial protein import"
XP_049799202.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049803785.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049789065.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049815097.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049806848.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049795229.1	9	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049808850.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049806450.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049793397.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049816793.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049802742.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049816404.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049797787.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049796825.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049813396.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Neutrophil degranulation";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049811813.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049793065.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049790509.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049792769.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049804782.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049807117.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049814774.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049789454.1	8	MetaCyc: PWY-7193;MetaCyc: PWY-6556;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5	"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism"
XP_049794381.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_049807603.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049814888.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_049795793.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049803228.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049799826.1	6	MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049811351.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination"
XP_049813526.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049789149.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049803517.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;Reactome: R-HSA-1483166	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Synthesis of PA"
XP_049802959.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049796959.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049791160.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_049792064.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049807389.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049791457.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108	"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_049812052.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049811124.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049810319.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049790689.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049801956.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049807728.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049797625.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049795224.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)"
XP_049795285.1	12	KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-3801	"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)"
XP_049802711.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049801729.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049814890.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_049807981.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049788732.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_049800815.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049790337.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery"
XP_049810772.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049807840.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049800833.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_049804658.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049802641.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_049795916.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049789365.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049813392.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_049811501.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049809167.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801212.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049794290.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049815610.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-165054	"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA"
XP_049794621.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049801021.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049814953.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049815515.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_049807260.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_049814310.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049793556.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842	"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"HDMs demethylate histones"
XP_049794795.1	19	KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6969;Reactome: R-HSA-70263	"Pyruvate metabolism";"Cysteine and methionine metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis"
XP_049789002.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049804384.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049803707.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_049807304.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_049812704.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049815566.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049809643.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811553.1	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
XP_049801168.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049801703.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049801973.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049796836.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049802853.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049805074.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049801434.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_049802812.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049815921.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049793051.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049802305.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049792038.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049792655.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049810892.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049805799.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049804068.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4041	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle"
XP_049804803.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451	"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis"
XP_049811413.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049814780.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049793946.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51	"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism"
XP_049808798.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049807445.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049812394.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049800859.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049809790.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049809704.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049806813.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049816713.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049802867.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049792645.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049809952.1	17	Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-5358606	"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049791444.1	22	MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7601;MetaCyc: PWY-7049;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7727;MetaCyc: PWY-5353	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"
XP_049789577.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049793030.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049798932.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049808920.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049814731.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049805937.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049814196.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes"
XP_049805410.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049812496.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049798975.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049800176.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-1971475	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049802965.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049806768.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049800670.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_049801660.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049790104.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049794715.1	14	Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-1474228;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665	"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells"
XP_049805794.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_049798460.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_049808829.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049809680.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_049812509.1	7	Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Thiamine metabolism";"Pyrimidine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049809335.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049804043.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802429.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049795924.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049788797.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049806804.1	2	Reactome: R-HSA-8866652;Reactome: R-HSA-5357905	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TNFR1 signaling"
XP_049814246.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196	"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling"
XP_049810656.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049800364.1	13	MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5	"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Propanoate metabolism"
XP_049800920.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049795658.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425	"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049801748.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049801582.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049794371.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049790719.1	13	Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-437239	"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1"
XP_049789632.1	33	Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8939236	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049804948.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049807985.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049799142.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049812312.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049801199.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049792822.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049802643.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049805235.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049814753.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049790896.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049815672.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049806749.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049796844.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049796252.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049807788.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049795034.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049809606.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_049811147.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation"
XP_049801115.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049804850.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049801043.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049798055.1	7	Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Cristae formation"
XP_049815285.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049802677.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049793364.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049794199.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800814.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049810364.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049815958.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049792928.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049816118.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049792929.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049807293.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049792191.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049815734.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_049811079.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049789475.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_049805461.1	12	KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9	"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049793972.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812453.1	5	Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;MetaCyc: PWY-7511;Reactome: R-HSA-5358346	"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination";"Hedgehog ligand biogenesis"
XP_049802635.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_049803474.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049789986.1	22	MetaCyc: PWY-6992;MetaCyc: PWY-7385;MetaCyc: PWY-8013;MetaCyc: PWY-7347;MetaCyc: PWY-3801;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-621;MetaCyc: PWY-5514;KEGG: 00010+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-5384;MetaCyc: PWY-622;Reactome: R-HSA-5628897;KEGG: 00500+5.3.1.9;Reactome: R-HSA-70171;MetaCyc: PWY-5054;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6981	"1,5-anhydrofructose degradation";"1,3-propanediol biosynthesis (engineered)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose biosynthesis III";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Sucrose degradation III (sucrose invertase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Sucrose degradation IV (sucrose phosphorylase)";"Starch biosynthesis";"TP53 Regulates Metabolic Genes";"Starch and sucrose metabolism";"Glycolysis";"D-sorbitol biosynthesis I";"Sucrose biosynthesis II";"Neutrophil degranulation";"Chitin biosynthesis"
XP_049805597.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049789127.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049809794.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049791510.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049805413.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049812793.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049814423.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_049802469.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049810652.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_049797453.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049789742.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049805981.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_049801531.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049802740.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049803193.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049791491.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_049788851.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_049807673.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049792974.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049813641.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049810288.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_049811780.1	8	KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481	"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate"
XP_049811373.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049808374.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230	"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA"
XP_049788763.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049789342.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049807141.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_049804565.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049789230.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049804053.1	7	Reactome: R-HSA-70635;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-31;MetaCyc: PWY-46	"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"Urea cycle";"Canavanine degradation";"Putrescine biosynthesis III"
XP_049811248.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049816774.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049810545.1	18	MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642	"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation"
XP_049789267.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_049801570.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049794137.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049816020.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049808710.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049810677.1	24	KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-165158;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-5218921;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-354192;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1	"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"RSK activation";"CD28 dependent PI3K/Akt signaling";"Activation of AKT2";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated cell proliferation";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Integrin signaling";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection"
XP_049800898.1	22	MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7049;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7727;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-5080	"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I"
XP_049815979.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_049788654.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049811355.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049805993.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049792512.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049816206.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049807865.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049812060.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049811114.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049805498.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049794404.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049809945.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_049793943.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049816464.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049803397.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_049805390.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-163359	"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation"
XP_049805039.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2151201	"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis"
XP_049804100.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467	"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Kinesins";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs"
XP_049810858.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049801518.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049814879.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049808849.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049794244.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049789614.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049799721.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049804305.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049797685.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_049811384.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049805554.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17	"Pentose phosphate pathway";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism"
XP_049800689.1	4	KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
XP_049806512.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049806124.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_049814092.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049795729.1	9	Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-196780;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1	"Gluconeogenesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)"
XP_049812747.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049803848.1	17	MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086	"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_049801213.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993	"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors"
XP_049803394.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)"
XP_049810575.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802285.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_049807133.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804079.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049814986.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049793949.1	4	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"G1/S-Specific Transcription"
XP_049793553.1	7	Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"HDMs demethylate histones";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription"
XP_049801102.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)"
XP_049810274.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049789752.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049809839.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049811161.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049797022.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049810816.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_049807176.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049801180.1	4	KEGG: 00340+3.5.2.7;MetaCyc: PWY-5028;MetaCyc: PWY-5030;Reactome: R-HSA-70921	"Histidine metabolism";"L-histidine degradation II";"L-histidine degradation III";"Histidine catabolism"
XP_049804128.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049792658.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049807363.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation"
XP_049799397.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049802873.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_049800144.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049809276.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807893.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049804581.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_049792043.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049804994.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049798906.1	2	Reactome: R-HSA-8866652;Reactome: R-HSA-5357905	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TNFR1 signaling"
XP_049794315.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049813542.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049812746.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049788590.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"RAF activation";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_049799976.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001	"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism"
XP_049790975.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_049806245.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049804986.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049791829.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049794133.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049816533.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049791455.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049791555.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049814596.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049814515.1	10	MetaCyc: PWY-5757;KEGG: 00440+5.4.2.9;MetaCyc: PWY-6839;MetaCyc: PWY-7769;KEGG: 00998+5.4.2.9;MetaCyc: PWY-8067;MetaCyc: PWY-7510;MetaCyc: PWY-7419;MetaCyc: PWY-6322;MetaCyc: PWY-6682	"Fosfomycin biosynthesis";"Phosphonate and phosphinate metabolism";"2-aminoethylphosphonate biosynthesis";"Phosalacine biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Methylphosphonate biosynthesis";"Rhizocticin A and B biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Dehydrophos biosynthesis"
XP_049802613.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049815346.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049808275.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_049803642.1	6	Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795	"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling"
XP_049808417.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049790412.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049806051.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049806272.1	33	Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion"
XP_049812974.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804592.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049816009.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors"
XP_049805372.1	14	MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049794179.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_049788542.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_049792402.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_049813343.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
XP_049790022.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049789119.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049793546.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_049792914.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049797114.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049795042.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049799873.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049789159.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049814108.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049789812.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_049799971.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049816790.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049802750.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049800470.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049802016.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049790699.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049810046.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049793283.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049806598.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049791566.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049790761.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination"
XP_049790728.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049791283.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_049796467.1	3	Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_049811959.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049803052.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-7233	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_049812519.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049807898.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049803618.1	32	Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-76042	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049808653.1	13	Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883	"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II"
XP_049802102.1	29	Reactome: R-HSA-912446;Reactome: R-HSA-69473;KEGG: 04926+2.7.11.1;Reactome: R-HSA-349425;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-69541;Reactome: R-HSA-5685942;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-6803204;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6803207;Reactome: R-HSA-5685938;Reactome: R-HSA-6804760;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607	"Meiotic recombination";"G2/M DNA damage checkpoint";"Relaxin signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"mTOR signaling pathway";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Stabilization of p53";"HDR through Homologous Recombination (HRR)";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human cytomegalovirus infection";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Methylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends"
XP_049815723.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049814256.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049796144.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049807074.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049800783.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049797716.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049813143.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_049789114.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049805605.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049808381.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804946.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049800442.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049791280.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049814391.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049794291.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049790804.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049812393.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049811736.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049804648.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_049792883.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049800899.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Regulation of PTEN localization"
XP_049814678.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049800335.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049789325.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049791362.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049805641.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049807337.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049794155.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_049793441.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049808715.1	5	MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_049791932.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049790891.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049808254.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049805285.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049813124.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816765.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049794071.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049808568.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049797718.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_049816755.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049815224.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049813426.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793523.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049802511.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_049790609.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049799222.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049795914.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049789396.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_049794063.1	11	Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-174437	"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand"
XP_049812755.1	11	Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-68952	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"DNA replication initiation"
XP_049802834.1	10	Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-3299685	"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species"
XP_049815945.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049801113.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049810129.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049804608.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049804558.1	2	Reactome: R-HSA-8875656;Reactome: R-HSA-8873719	"MET receptor recycling";"RAB geranylgeranylation"
XP_049801540.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049806670.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange"
XP_049808819.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807140.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049808919.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049793596.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049795152.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049811395.1	4	KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049807207.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049797599.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation"
XP_049813259.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049815192.1	11	KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Tunicamycin biosynthesis"
XP_049794260.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049800789.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049804382.1	3	KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_049792417.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_049794574.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Ether lipid metabolism"
XP_049798053.1	6	MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00680+2.6.1.52	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_049815692.1	31	MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-6113;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-5367;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7746;MetaCyc: PWY-5147;MetaCyc: PWY-8049;MetaCyc: PWY-6799;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;MetaCyc: PWY-4381	"";"Fatty acid biosynthesis";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Biotin metabolism";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_049804002.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_049788803.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049806636.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049797110.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-166208	"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling"
XP_049789432.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049801022.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049806517.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_049789250.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049808912.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049810327.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049789496.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_049799054.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049807281.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049789703.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693	"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling"
XP_049814491.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_049807689.1	12	Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;MetaCyc: PWY-6277	"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Biotin transport and metabolism";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_049816873.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049802502.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049793146.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049792894.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049802842.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_049799536.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_049811182.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049807787.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049802703.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049805370.1	13	Reactome: R-HSA-2024096;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206308;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695	"HS-GAG degradation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"MPS IV - Morquio syndrome B";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Neutrophil degranulation"
XP_049806602.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049788853.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049806429.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049808498.1	7	KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;MetaCyc: PWY-7158	"Phenylalanine metabolism";"Phenylketonuria";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V"
XP_049790409.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049813170.1	4	KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_049802715.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049794730.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049800523.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049809754.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049806569.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049792983.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049815578.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049798299.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049790218.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049812898.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049805376.1	6	MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway"
XP_049809637.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049815177.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049790015.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049801384.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049801422.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049789321.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-6798695;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"Neutrophil degranulation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049793383.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049794855.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049804646.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049805525.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_049805451.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049793631.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049810212.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049802815.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049794039.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress"
XP_049810918.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170660	"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase activating pathway"
XP_049801586.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049805625.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Nephrin family interactions";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049802126.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049797425.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049793192.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789345.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049806797.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049808928.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049795237.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049813498.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049792927.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049812426.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049794077.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049794036.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_049809882.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_049793162.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049809088.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049794403.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049814157.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049804867.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_049793657.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049799818.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049815802.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049810717.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_049793135.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049790841.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049813906.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049806888.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049810189.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049801501.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049799375.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049791620.1	15	Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700	"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_049789694.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049815671.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049806805.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049790013.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049807505.1	9	MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism"
XP_049813107.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049805162.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049811791.1	17	Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-174154	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin"
XP_049814199.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049808274.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049795653.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049808141.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_049792718.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049805836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049804064.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049802532.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049807784.1	6	KEGG: 00670+2.1.2.5;MetaCyc: PWY-5030;KEGG: 00670+4.3.1.4+2.1.2.5;Reactome: R-HSA-70921;MetaCyc: PWY-5497;KEGG: 00340+2.1.2.5	"One carbon pool by folate";"L-histidine degradation III";"One carbon pool by folate";"Histidine catabolism";"Purine nucleobases degradation II (anaerobic)";"Histidine metabolism"
XP_049811948.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_049814274.1	12	MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1	"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Methane metabolism";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes"
XP_049794086.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049802903.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049807591.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049814683.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049806929.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_049814602.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049815378.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049809769.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_049795714.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049806539.1	7	MetaCyc: PWY-6724;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-7238	"Starch degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Glycogen degradation II";"Sucrose biosynthesis II"
XP_049809879.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793121.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049809155.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049810646.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049811491.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049807434.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049796581.1	10	Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1	"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism";"Inositol phosphate metabolism"
XP_049794084.1	4	Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10	"Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049792992.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2"
XP_049811775.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049816749.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism"
XP_049793127.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049798088.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-375276	"G alpha (s) signalling events";"Peptide ligand-binding receptors"
XP_049790710.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049793620.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049804609.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049809147.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049800691.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049794350.1	52	Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-168325;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-167290;Reactome: R-HSA-76071;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-73780;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Viral Messenger RNA Synthesis";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049812886.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049809789.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049800893.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049795575.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049789160.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049806921.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049816884.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049801440.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049802452.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049814471.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049812713.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049794243.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049789536.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049816414.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791762.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049815267.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_049807476.1	10	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Sphingolipid metabolism"
XP_049813026.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049790410.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049791217.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049812895.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049803026.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049798754.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-1268020;Reactome: R-HSA-111459;Reactome: R-HSA-3299685	"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species"
XP_049801662.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049805497.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049794141.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049808926.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049789941.1	4	MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_049810187.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049801410.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049804360.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_049793161.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_049812638.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049807477.1	10	Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23	"MPS VII - Sly syndrome";"HS-GAG degradation";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation"
XP_049805402.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049791914.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049813055.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049794783.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049800843.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049797847.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049789951.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049816819.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-380994	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049793924.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049795486.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049791511.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049800524.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049811832.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049807471.1	10	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation"
XP_049801062.1	13	KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;Reactome: R-HSA-196836;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6842	"Drug metabolism - other enzymes";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification II"
XP_049815161.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049803987.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4041	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle"
XP_049804278.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049812908.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_049791212.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049808871.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_049793184.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049794743.1	12	KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385	"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)"
XP_049807470.1	10	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916	"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation"
XP_049793068.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049800890.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_049791092.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049809432.1	5	Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6804756	"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation"
XP_049793149.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789308.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049789220.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049790001.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049805932.1	6	MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_049814616.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049792640.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049791545.1	7	MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-7294	"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"D-xylose degradation IV"
XP_049815695.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"SUMOylation of DNA methylation proteins"
XP_049811375.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049797914.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049814902.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049816883.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049814746.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049804484.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049800349.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049804376.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049813654.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049801530.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049811487.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049815398.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049811462.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049793050.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_049805114.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049795927.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_049799245.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049806271.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism"
XP_049803954.1	10	Reactome: R-HSA-9637628;Reactome: R-HSA-1461957;Reactome: R-HSA-1236974;Reactome: R-HSA-168188;Reactome: R-HSA-5603041;Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-5686938;Reactome: R-HSA-168179;Reactome: R-HSA-6798695	"Modulation by Mtb of host immune system";"Beta defensins";"ER-Phagosome pathway";"Toll Like Receptor TLR6:TLR2 Cascade";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Regulation of TLR by endogenous ligand";"Toll Like Receptor TLR1:TLR2 Cascade";"Neutrophil degranulation"
XP_049813352.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049802571.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049804042.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049815531.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049808836.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049811163.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049815727.1	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_049797771.1	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049789482.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049807701.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049812738.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049812449.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049793987.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049807988.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049795128.1	30	Reactome: R-HSA-69656;Reactome: R-HSA-211163;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-111447;Reactome: R-HSA-6804758;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-5218920;Reactome: R-HSA-8876198;Reactome: R-HSA-198323;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-9634638;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-6804759;Reactome: R-HSA-1257604;Reactome: R-HSA-389513;Reactome: R-HSA-199418;Reactome: R-HSA-8941332;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-198693;KEGG: 05165+2.7.11.1	"Cyclin A:Cdk2-associated events at S phase entry";"AKT-mediated inactivation of FOXO1A";"Thermogenesis";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"Activation of BAD and translocation to mitochondria";"Regulation of TP53 Activity through Acetylation";"Relaxin signaling pathway";"mTOR signaling pathway";"Cyclin E associated events during G1/S transition";"VEGFR2 mediated vascular permeability";"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the cytosol";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"PI3K-Akt signaling pathway";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Association with Co-factors";"PIP3 activates AKT signaling";"CTLA4 inhibitory signaling";"Negative regulation of the PI3K/AKT network";"RUNX2 regulates genes involved in cell migration";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Downregulation of ERBB2:ERBB3 signaling";"AKT phosphorylates targets in the nucleus";"Human papillomavirus infection"
XP_049791759.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_049811945.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049808283.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049794815.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049790962.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-190873	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation"
XP_049792163.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049792166.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049805773.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049803529.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049802239.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049805531.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517	"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid"
XP_049792333.1	5	KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_049797997.1	9	MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I"
XP_049805513.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049812128.1	8	Reactome: R-HSA-6791461;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861	"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_049814492.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049791227.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049812282.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_049792234.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049798309.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_049803795.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165	"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049792909.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569	"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049789240.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049791691.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium"
XP_049793739.1	17	KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Propanoate metabolism";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_049812047.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049809629.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049789045.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049801517.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049810357.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049797100.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-429947	"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA"
XP_049809095.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049789981.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049814777.1	34	Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-9639288;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464	"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins"
XP_049813959.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049806479.1	4	KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241	"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Peroxisomal protein import"
XP_049816824.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_049808370.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049795279.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049798052.1	6	KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010	"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_049797948.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049806149.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen degradation"
XP_049800618.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049794729.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049812090.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Dual incision in TC-NER"
XP_049802527.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049788955.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049811910.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_049799327.1	5	Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825	"Iron uptake and transport";"Neddylation";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis"
XP_049811489.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049810625.1	12	Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange"
XP_049803393.1	4	MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049792212.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049814237.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049808931.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049802082.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_049791206.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049811827.1	13	MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2201	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Folate transformations II (plants)";"L-histidine degradation III";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I"
XP_049813019.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_049805927.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049810422.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178	"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans"
XP_049799276.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049789203.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049804171.1	3	Reactome: R-HSA-5173105;KEGG: 00515+2.7.1.183;MetaCyc: PWY-7979	"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_049807253.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8053	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II"
XP_049794214.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049810067.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049815088.1	182	Reactome: R-HSA-975144;Reactome: R-HSA-209543;Reactome: R-HSA-912631;Reactome: R-HSA-5607761;Reactome: R-HSA-9613829;Reactome: R-HSA-5689896;Reactome: R-HSA-69017;Reactome: R-HSA-5696394;Reactome: R-HSA-174084;Reactome: R-HSA-201681;Reactome: R-HSA-5696397;Reactome: R-HSA-179409;Reactome: R-HSA-5656121;Reactome: R-HSA-2173791;Reactome: R-HSA-8876493;Reactome: R-HSA-1799339;Reactome: R-HSA-450408;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-211733;Reactome: R-HSA-9637628;Reactome: R-HSA-8856825;Reactome: R-HSA-2122948;Reactome: R-HSA-5696400;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-5678895;Reactome: R-HSA-937039;Reactome: R-HSA-5205685;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-9033241;Reactome: R-HSA-156827;Reactome: R-HSA-174154;Reactome: R-HSA-8849469;Reactome: R-HSA-5607764;Reactome: R-HSA-6782210;Reactome: R-HSA-5610780;Reactome: R-HSA-9646399;Reactome: R-HSA-6783310;Reactome: R-HSA-1358803;Reactome: R-HSA-174048;Reactome: R-HSA-72706;Reactome: R-HSA-9013973;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2894862;Reactome: R-HSA-8948747;Reactome: R-HSA-1253288;Reactome: R-HSA-2559582;Reactome: R-HSA-9645460;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5676590;Reactome: R-HSA-9636383;Reactome: R-HSA-977225;Reactome: R-HSA-174490;Reactome: R-HSA-975110;Reactome: R-HSA-174178;Reactome: R-HSA-1169408;Reactome: R-HSA-937072;Reactome: R-HSA-209560;Reactome: R-HSA-5689603;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-8939902;Reactome: R-HSA-110314;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-6804757;Reactome: R-HSA-2644606;Reactome: R-HSA-5684264;Reactome: R-HSA-5357905;Reactome: R-HSA-5654726;Reactome: R-HSA-72702;Reactome: R-HSA-6782135;Reactome: R-HSA-174184;Reactome: R-HSA-8856828;Reactome: R-HSA-1295596;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5685942;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-168927;Reactome: R-HSA-936964;Reactome: R-HSA-5610785;Reactome: R-HSA-5675482;Reactome: R-HSA-175474;Reactome: R-HSA-5656169;Reactome: R-HSA-917937;Reactome: R-HSA-450321;Reactome: R-HSA-5655862;Reactome: R-HSA-205043;Reactome: R-HSA-5693607;Reactome: R-HSA-2173796;Reactome: R-HSA-1236382;Reactome: R-HSA-8939236;Reactome: R-HSA-8866652;Reactome: R-HSA-936440;Reactome: R-HSA-72695;Reactome: R-HSA-9013507;Reactome: R-HSA-3769402;Reactome: R-HSA-8863795;Reactome: R-HSA-2122947;Reactome: R-HSA-382556;Reactome: R-HSA-975163;Reactome: R-HSA-110312;Reactome: R-HSA-3785653;Reactome: R-HSA-162588;Reactome: R-HSA-69231;Reactome: R-HSA-2173795;Reactome: R-HSA-2467813;Reactome: R-HSA-168928;Reactome: R-HSA-202424;Reactome: R-HSA-2691232;Reactome: R-HSA-901032;Reactome: R-HSA-6781823;Reactome: R-HSA-4641263;Reactome: R-HSA-5654732;Reactome: R-HSA-156902;Reactome: R-HSA-5689877;Reactome: R-HSA-2979096;Reactome: R-HSA-8941858;Reactome: R-HSA-2565942;Reactome: R-HSA-5675221;Reactome: R-HSA-8866654;Reactome: R-HSA-2173788;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-192823;Reactome: R-HSA-3134975;Reactome: R-HSA-1234176;Reactome: R-HSA-937042;Reactome: R-HSA-69481;Reactome: R-HSA-9615710;Reactome: R-HSA-937041;Reactome: R-HSA-5654733;Reactome: R-HSA-349425;Reactome: R-HSA-5357956;Reactome: R-HSA-9633012;Reactome: R-HSA-110320;Reactome: R-HSA-6804760;Reactome: R-HSA-6804756;Reactome: R-HSA-5696395;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-917729;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-72649;Reactome: R-HSA-168638;Reactome: R-HSA-69541;Reactome: R-HSA-5654727;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-8875360;Reactome: R-HSA-975957;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2672351;Reactome: R-HSA-3322077;Reactome: R-HSA-9014325;Reactome: R-HSA-5689901;Reactome: R-HSA-6781827;Reactome: R-HSA-8948751;Reactome: R-HSA-445989;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-6807004;Reactome: R-HSA-5610783;Reactome: R-HSA-532668;Reactome: R-HSA-450302	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"p75NTR recruits signalling complexes";"Regulation of signaling by CBL";"Dectin-1 mediated noncanonical NF-kB signaling";"Chaperone Mediated Autophagy";"Ovarian tumor domain proteases";"CDK-mediated phosphorylation and removal of Cdc6";"DNA Damage Recognition in GG-NER";"Autodegradation of Cdh1 by Cdh1:APC/C";"TCF dependent signaling in response to WNT";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APC-Cdc20 mediated degradation of Nek2A";"Translesion synthesis by POLI";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"InlA-mediated entry of Listeria monocytogenes into host cells";"SRP-dependent cotranslational protein targeting to membrane";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Modulation by Mtb of host immune system";"Cargo recognition for clathrin-mediated endocytosis";"Activated NOTCH1 Transmits Signal to the Nucleus";"Dual Incision in GG-NER";"EGFR downregulation";"Selenocysteine synthesis";"Defective CFTR causes cystic fibrosis";"IRAK1 recruits IKK complex";"Pink/Parkin Mediated Mitophagy";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Peroxisomal protein import";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdc20 mediated degradation of Securin";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"CLEC7A (Dectin-1) signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of GLI1 by the proteasome";"Aggrephagy";"Fanconi Anemia Pathway";"Downregulation of ERBB2:ERBB3 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TICAM1-dependent activation of IRF3/IRF7";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PTEN localization";"Downregulation of ERBB4 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Alpha-protein kinase 1 signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"NIK-->noncanonical NF-kB signaling";"Prevention of phagosomal-lysosomal fusion";"Amyloid fiber formation";"Membrane binding and targetting of GAG proteins";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ISG15 antiviral mechanism";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NF-kB is activated and signals survival";"UCH proteinases";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of RUNX2 expression and activity";"Recognition of DNA damage by PCNA-containing replication complex";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of TNFR1 signaling";"Negative regulation of FGFR1 signaling";"Ribosomal scanning and start codon recognition";"Dual incision in TC-NER";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Clathrin-mediated endocytosis";"Spry regulation of FGF signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"HDR through Homologous Recombination (HRR)";"Vpu mediated degradation of CD4";"Circadian Clock";"TICAM1, RIP1-mediated IKK complex recruitment";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"GLI3 is processed to GLI3R by the proteasome";"Regulation of necroptotic cell death";"Assembly Of The HIV Virion";"Termination of translesion DNA synthesis";"Iron uptake and transport";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Translesion synthesis by POLK";"NRIF signals cell death from the nucleus";"Processing of DNA double-strand break ends";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Negative regulators of DDX58/IFIH1 signaling";"Formation of the ternary complex, and subsequently, the 43S complex";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Deactivation of the beta-catenin transactivating complex";"Downregulation of ERBB2 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"ABC-family proteins mediated transport";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by REV1";"Myoclonic epilepsy of Lafora";"Budding and maturation of HIV virion";"Cyclin D associated events in G1";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Separation of Sister Chromatids";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"ER Quality Control Compartment (ERQC)";"Formation of TC-NER Pre-Incision Complex";"Regulation of FZD by ubiquitination";"Negative regulation of FGFR3 signaling";"Peptide chain elongation";"Josephin domain DUBs";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of RUNX3 expression and activity";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of MAPK pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Downregulation of TGF-beta receptor signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Viral mRNA Translation";"Regulation of innate immune responses to cytosolic DNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"IRAK2 mediated activation of TAK1 complex";"G2/M Checkpoints";"Late endosomal microautophagy";"IKK complex recruitment mediated by RIP1";"Negative regulation of FGFR4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR1-induced NFkappaB signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Activity through Phosphorylation";"Formation of Incision Complex in GG-NER";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Translation initiation complex formation";"NOD1/2 Signaling Pathway";"Stabilization of p53";"Negative regulation of FGFR2 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Stimuli-sensing channels";"Glycogen synthesis";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Metalloprotease DUBs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN stability and activity";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Negative regulation of MET activity";"Degradation of GLI2 by the proteasome";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"activated TAK1 mediates p38 MAPK activation"
XP_049807321.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807085.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049815155.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049799942.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049798530.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_049809213.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791157.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049813232.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049807896.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_049799043.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_049809169.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049802734.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859	"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly"
XP_049801946.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049792849.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049802714.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049814181.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049789750.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049807947.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049806544.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049809253.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049790281.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049810167.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049811191.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049807793.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804049.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049797773.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049790289.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049791781.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049806946.1	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026	"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Platelet sensitization by LDL";"LDL remodeling";"LDL clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"VLDL clearance";"VLDL assembly";"Chylomicron clearance"
XP_049810039.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815051.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049788769.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049807859.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049795165.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756	"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Synthesis of PC";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation"
XP_049815364.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049814238.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049814166.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049794623.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_049808214.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049805414.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049803478.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049812303.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049790000.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049810135.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049788930.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049809800.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049790669.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_049800705.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049804970.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049797651.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_049794854.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049800547.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_049805287.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049808257.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049815053.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049789356.1	5	KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Pyruvate metabolism"
XP_049790638.1	20	MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-5136	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049797786.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049799148.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049807118.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049796092.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049802301.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4085377	"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of SUMOylation proteins"
XP_049810566.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049809226.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049803190.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805623.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"Neutrophil degranulation";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049797987.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049794798.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049810705.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis"
XP_049789095.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049811751.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049791131.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_049812136.1	24	Reactome: R-HSA-9009391;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-416476	"Extra-nuclear estrogen signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"G alpha (z) signalling events";"G alpha (q) signalling events"
XP_049803595.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049793252.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049804880.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049797602.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049803518.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_049806168.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049805626.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049802852.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049796247.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049792232.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049801505.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049810787.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049804665.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-9656256;Reactome: R-HSA-9656255;Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-5649702;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049807610.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049809165.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049794107.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049793245.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis"
XP_049788563.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends"
XP_049789001.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049788995.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049812935.1	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5664	"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_049804974.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049804607.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049812162.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049796774.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049789006.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049793655.1	14	MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055	"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis"
XP_049810340.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_049800352.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_049792110.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049805742.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049816415.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049792891.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049799273.1	1	Reactome: R-HSA-5673001	"RAF/MAP kinase cascade"
XP_049814067.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049788890.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049814935.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049802744.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049802782.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049801720.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049802441.1	10	MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722	"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_049800805.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049791569.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049789241.1	13	MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049808326.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
XP_049815332.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049806262.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049800307.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049790518.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049803401.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049816788.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049792977.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049797833.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049800467.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_049804092.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049791516.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049813062.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049802003.1	18	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-975957;KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049814281.1	9	MetaCyc: PWY-5265;KEGG: 00513+2.4.1.141;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Peptidoglycan biosynthesis II (staphylococci)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049810631.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858	"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity"
XP_049815032.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049800345.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049789979.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049806814.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833	"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly"
XP_049816220.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation"
XP_049806118.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049805482.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049793259.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049808807.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049789299.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802473.1	5	Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-446388	"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_049799445.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049810752.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049805388.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049789223.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049815855.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049809148.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049808666.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049805496.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049813319.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049813350.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049788799.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049788980.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049807132.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805587.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049792995.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8986944	"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2"
XP_049804649.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_049809356.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049796041.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_049791786.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049811159.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_049796248.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-73762	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"RNA Polymerase I Transcription Initiation"
XP_049810525.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049804721.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049804235.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411	"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere"
XP_049801272.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317	"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_049814801.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_049811328.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049791583.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_049816119.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049813142.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049815054.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049788505.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049811348.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049802551.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049812737.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049792893.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049807131.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049794789.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049816678.1	8	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_049815227.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049793177.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806510.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1	"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection"
XP_049815644.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049798952.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049807257.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800994.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049815909.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049794100.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049808667.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049793126.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049804640.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049814214.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-8964539	"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism"
XP_049808884.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_049789870.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049797995.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049789115.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis"
XP_049802049.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975	"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA"
XP_049789424.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049808060.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049804485.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049792847.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049803048.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049801936.1	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26	"Plasmalogen biosynthesis";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Ether lipid metabolism"
XP_049814292.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049794857.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049802847.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049815041.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049794417.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049808857.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049788808.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5358606	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049790814.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049803485.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049806576.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049804317.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049801243.1	7	KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation"
XP_049802789.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049811397.1	4	KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219	"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis"
XP_049798133.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049800886.1	9	Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69231	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1"
XP_049791938.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049815793.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049801156.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049800460.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017	"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Neddylation";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6"
XP_049794231.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049812465.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049808067.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049797967.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_049789116.1	5	MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Ophthalmate biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_049802407.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049790783.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049814448.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049801751.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049815853.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049811486.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049804206.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049800040.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049805393.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049805679.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049793206.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049806599.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049812946.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049789084.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049805489.1	12	MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6936	"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)"
XP_049789153.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049804873.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049799655.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049813553.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049802337.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049808264.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170	"ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions"
XP_049806649.1	6	Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049791219.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049809506.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049814084.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049813388.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Neutrophil degranulation";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049792793.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049812092.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049801502.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049807892.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049815829.1	7	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway"
XP_049814173.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049809124.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049793623.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049796509.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_049800353.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_049792193.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049808061.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049789505.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5696397	"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Polymerase switching";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049809905.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_049811295.1	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_049801099.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049816857.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049793083.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049791862.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801268.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049813405.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049814008.1	14	Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4	"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_049808185.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049794136.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049805170.1	57	Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-211733	"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_049793365.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049805730.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049802080.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_049791226.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049814498.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_049805490.1	12	MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-2821;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6842	"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II"
XP_049814555.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049809877.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049816108.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_049807965.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II"
XP_049805006.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049799639.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049803493.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-167590	"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation"
XP_049795996.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_049801749.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049788887.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049813458.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049791546.1	7	MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-7294;MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7295	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"D-xylose degradation IV";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV"
XP_049805991.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049794757.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049816152.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049804123.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399	"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors"
XP_049791038.1	34	Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-69202;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-69273;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-69656;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes"
XP_049790901.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049795043.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049805499.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049790021.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049790110.1	6	Reactome: R-HSA-186797;Reactome: R-HSA-8957275;Reactome: R-HSA-216083;Reactome: R-HSA-381426;Reactome: R-HSA-8949275;Reactome: R-HSA-1474228	"Signaling by PDGF";"Post-translational protein phosphorylation";"Integrin cell surface interactions";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RUNX3 Regulates Immune Response and Cell Migration";"Degradation of the extracellular matrix"
XP_049791919.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049801508.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049804901.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049795957.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049808733.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808654.1	13	KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52	"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049804893.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049808743.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049812146.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049810284.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049799945.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049799446.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815410.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049801549.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049810960.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049793975.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805044.1	10	Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"RSK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049789506.1	4	Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815322.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049811111.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049796376.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049800609.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049811267.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049791670.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049790785.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049797376.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049805488.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-2821;Reactome: R-HSA-71240;MetaCyc: PWY-6936	"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)"
XP_049814983.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049813990.1	14	KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4	"Ether lipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Glycerolipid metabolism";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_049804176.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_049814732.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049793813.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049798086.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049789619.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049816867.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049789626.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049812696.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049801521.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049793172.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789232.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_049807938.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049793507.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049789690.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049816812.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049789459.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049816196.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049813921.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049804949.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049812080.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049795247.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049792826.1	13	Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920	"mTORC1-mediated signalling";"HSF1-dependent transactivation";"mTOR signalling";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"Macroautophagy";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability"
XP_049790688.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049792160.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049805711.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049790411.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049816852.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049815613.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049809919.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049807879.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_049807813.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049810414.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_049815565.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049793136.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049809471.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway"
XP_049800861.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049795792.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049788983.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049789320.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6798695	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Neutrophil degranulation"
XP_049789983.1	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
XP_049813061.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049789202.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049794218.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049788893.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049805855.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049801585.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049801420.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049802663.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049812079.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049791804.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_049793414.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049788778.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_049813532.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049811264.1	7	Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690	"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events"
XP_049805484.1	12	MetaCyc: PWY-6936;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6309;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901	"Seleno-amino acid biosynthesis (plants)";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine"
XP_049791100.1	14	MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5101;MetaCyc: PWY-7767;MetaCyc: PWY-5076;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42	"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)";"L-leucine degradation III";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"L-isoleucine degradation II";"Glucosinolate biosynthesis"
XP_049791567.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049792215.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049815404.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049806294.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049813443.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411	"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere"
XP_049802549.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049800443.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049794885.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049813556.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049803574.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049810491.1	10	Reactome: R-HSA-69205;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-3841;MetaCyc: PWY-7199;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210	"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049795654.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049789746.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049801364.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049807052.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049812143.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049806077.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049792852.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049796638.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_049789271.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_049794847.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049805148.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049795112.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049789493.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049811218.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_049814152.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049801120.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs"
XP_049789875.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049804982.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049802805.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565	"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049790019.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049808804.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049793535.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049801273.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_049813442.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049807825.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049810231.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805453.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049813293.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049789036.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
XP_049816202.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_049804874.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049801971.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049810234.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049800918.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049792878.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049816307.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049813058.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049812104.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049808501.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049815651.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049815106.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049813125.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670	"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway"
XP_049792994.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8986944	"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2"
XP_049813022.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049806227.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049788795.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049791071.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_049798584.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049804866.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)"
XP_049805769.1	9	MetaCyc: PWY-5757;MetaCyc: PWY-7769;MetaCyc: PWY-6839;KEGG: 00440+4.1.1.82;MetaCyc: PWY-8067;MetaCyc: PWY-6682;KEGG: 00998+4.1.1.82;MetaCyc: PWY-6322;MetaCyc: PWY-7510	"Fosfomycin biosynthesis";"Phosalacine biosynthesis";"2-aminoethylphosphonate biosynthesis";"Phosphonate and phosphinate metabolism";"Methylphosphonate biosynthesis";"Dehydrophos biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Phosphinothricin tripeptide biosynthesis";"Rhizocticin A and B biosynthesis"
XP_049792897.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808390.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049803891.1	16	Reactome: R-HSA-166058;Reactome: R-HSA-6811558;Reactome: R-HSA-5602680;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-3134963;Reactome: R-HSA-1236974;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-5603041	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 deficiency (TLR5)";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"ER-Phagosome pathway";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR2/4)"
XP_049812379.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049814175.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049813174.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049805318.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_049812302.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049810470.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049805456.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049800774.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-141430	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_049802844.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049808323.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049815495.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049794177.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049792211.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049812233.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049812416.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins";"MHC class II antigen presentation"
XP_049800358.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815126.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049792104.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049801357.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_049811591.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049815361.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736	"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors"
XP_049791515.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049803794.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049789167.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049789877.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049816756.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049797635.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049800860.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049816580.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049792907.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049814374.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049801659.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049811523.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509	"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling"
XP_049815045.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793663.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049815351.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049792915.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049795814.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049812126.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789319.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6798695	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Neutrophil degranulation"
XP_049812292.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049792141.1	11	Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-109704;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;MetaCyc: PWY-6352	"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide biosynthesis"
XP_049815803.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049790790.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049813892.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_049795380.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049797381.1	11	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_049808551.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815007.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049809361.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812266.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049802972.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236	"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049793988.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601	"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049812950.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_049797713.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049808408.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_049802035.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049800993.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_049789164.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049802432.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049812930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049793509.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049811352.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049790716.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049804713.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_049804019.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049803643.1	6	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling"
XP_049813255.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_049793139.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049794862.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049804871.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049815713.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049812806.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049801633.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049810415.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049805656.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049791729.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049796639.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049808841.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049790351.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049799301.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049788740.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049801640.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins"
XP_049795414.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11	"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism"
XP_049793666.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049793748.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049793589.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049793699.1	12	Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4	"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Purine metabolism";"Selenocompound metabolism"
XP_049816015.1	52	Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-167290;Reactome: R-HSA-76071;Reactome: R-HSA-5578749;Reactome: R-HSA-76061;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-73780;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-6807505	"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes"
XP_049798478.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049802451.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049797454.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049814275.1	12	MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118	"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol"
XP_049801745.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049797799.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_049789773.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049802546.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049811950.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_049808462.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049804754.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-427413	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression"
XP_049804377.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049795673.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049794414.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049804375.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049800370.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049810196.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049805852.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049804454.1	10	Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-202424	"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Downstream TCR signaling"
XP_049805634.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049792066.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049806861.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049813411.1	6	Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952	"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation"
XP_049812581.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049803641.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049799163.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_049812563.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049795251.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049806761.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049802727.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049791340.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049800903.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049807034.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049806247.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049800858.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049789340.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049793218.1	25	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-380270;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276	"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"Gap junction assembly";"Cilium Assembly";"Recruitment of mitotic centrosome proteins and complexes";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_049812332.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049807514.1	9	KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18	"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450"
XP_049809946.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_049808110.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049799287.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_049792959.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049815489.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049812776.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049802747.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049788839.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049811977.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049801931.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049801528.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049790873.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049791051.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_049811818.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049788752.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049805891.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049793112.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049809139.1	31	Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-6113;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-8049;MetaCyc: PWY-5971;MetaCyc: PWY-7663;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7746;MetaCyc: PWY-5973;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1	"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"Superpathway of mycolate biosynthesis";"";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Bacterial bioluminescence";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_049795227.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_049790906.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049814451.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049793199.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049810375.1	3	MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_049792048.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049808950.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804735.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484	"Chylomicron clearance";"VLDL assembly";"Scavenging by Class H Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"LDL clearance";"LDL remodeling";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors"
XP_049804083.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049808867.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049808435.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_049814661.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829	"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049801741.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049804277.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049816365.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049810394.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049790174.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
YP_010401638.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049795404.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_049805253.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis"
XP_049792184.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049810162.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049788804.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049810136.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049811916.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049792210.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049808366.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807777.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049808779.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049801187.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571	"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)"
XP_049815584.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049791225.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049816872.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049807982.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049803573.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049804469.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049803492.1	8	Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049791977.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049804858.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049808938.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_049816010.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049791538.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049789236.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049812390.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_049795157.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_049801018.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049791552.1	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049793442.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049792885.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049790295.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049793203.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789134.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049793710.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049808240.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049804868.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_049803615.1	57	Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Neddylation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_049811343.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049804750.1	11	Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097	"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"p38MAPK events";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway"
XP_049798954.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049802112.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-0;MetaCyc: PWY-6117	"Arginine and proline metabolism";"Putrescine degradation III";"Spermine and spermidine degradation I"
XP_049807987.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049811554.1	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
XP_049816917.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049815265.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049795910.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049813412.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3	"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Glycerophospholipid metabolism"
XP_049815549.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049788526.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049815872.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_049789701.1	6	Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712	"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling"
XP_049792185.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049805582.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049816065.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049810753.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-180910	"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs"
XP_049801114.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049808732.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049794202.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049802401.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049804995.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049805126.1	12	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049789938.1	4	KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049814639.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049806207.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049812074.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049790659.1	5	KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983	"Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)"
XP_049814242.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049788985.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049797040.1	1	Reactome: R-HSA-6805567	"Keratinization"
XP_049805164.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049790400.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276	"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"Gap junction assembly";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Kinesins";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_049803962.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7559	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway"
XP_049793159.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049815597.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049802706.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049806524.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_049811292.1	18	MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6	"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism"
XP_049809763.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049797860.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049810706.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_049806955.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049813177.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049811349.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049813796.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049813549.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049796663.1	24	Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-420092	"G alpha (s) signalling events";"G alpha (z) signalling events";"G alpha (q) signalling events";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors"
XP_049792799.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049812081.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049813365.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Neutrophil degranulation";"COPII-mediated vesicle transport"
XP_049800553.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049805211.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049812690.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_049789715.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049814997.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049815880.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_049810435.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049809899.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049812636.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803521.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049802651.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049808843.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793703.1	12	MetaCyc: PWY-6683;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932	"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Selenocompound metabolism";"Purine metabolism";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenate reduction"
XP_049808847.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049813700.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049793010.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade"
XP_049811204.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049807687.1	12	KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Biotin transport and metabolism";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049795732.1	9	Reactome: R-HSA-3371599;MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1	"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Pyruvate metabolism"
XP_049790037.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049814195.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049803799.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049802979.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049796710.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049803342.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049804037.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049803804.1	14	KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416	"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_049790894.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049790465.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049812996.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049793595.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049789853.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049800408.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049811667.1	8	KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism"
XP_049789258.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049811920.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049789737.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_049791043.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression"
XP_049814494.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049802787.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049813286.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049809706.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257	"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Kinesins";"Recycling pathway of L1";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Gap junction assembly";"HCMV Early Events";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_049808762.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049809352.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049802431.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049809632.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049810713.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049790034.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049815380.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049789259.1	18	MetaCyc: PWY-6969;Reactome: R-HSA-70263;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-7383;MetaCyc: PWY-6728;MetaCyc: PWY-1622;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methane metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism"
XP_049790838.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;Reactome: R-HSA-73817	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
XP_049794246.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049806515.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049813200.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049816089.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049801170.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049792243.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049814147.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049812540.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049801245.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049805982.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049809141.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049812931.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_049806013.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049793811.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049792032.1	5	KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049815101.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_049790183.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049789235.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049791999.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978	"Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production"
XP_049804113.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_049788935.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049791739.1	12	Reactome: R-HSA-1268020;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-6978	"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II"
XP_049801109.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049800548.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049788541.1	3	Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_049810183.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049810448.1	7	KEGG: 00280+1.3.8.7;MetaCyc: PWY-7094;Reactome: R-HSA-1989781;KEGG: 00071+1.3.8.7;Reactome: R-HSA-77288;Reactome: R-HSA-77348;Reactome: R-HSA-77346	"Valine, leucine and isoleucine degradation";"Fatty acid salvage";"PPARA activates gene expression";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA"
XP_049804801.1	5	MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049810432.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049811381.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049805791.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049799510.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049791215.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049805631.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049788688.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148	"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Kinesins";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049812373.1	7	MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049812980.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_049809798.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1"
XP_049812391.1	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049789680.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049811666.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis"
XP_049801589.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_049794284.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811172.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049807144.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049788565.1	7	Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-2559586	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence"
XP_049816712.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049802547.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049801550.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_049805143.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_049802454.1	42	KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7401;MetaCyc: PWY-6863;MetaCyc: PWY-5138;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7779;MetaCyc: PWY-5136;KEGG: 00903+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-6435;MetaCyc: PWY-5109;MetaCyc: PWY-7606;KEGG: 00623+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-6883;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7778;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17	"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Benzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Propanoate metabolism";"Fatty acid salvage";"Fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Limonene and pinene degradation";"Phenylalanine metabolism";"Androstenedione degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Toluene degradation";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Glutaryl-coa degradation";"Fatty acid elongation";"Geraniol degradation";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"2-methylpropene degradation";"Butanoate metabolism";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism"
XP_049811316.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049795928.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_049790877.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049813351.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049800963.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049801218.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049793454.1	56	Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258	"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Degradation of DVL"
XP_049808806.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049791293.1	4	Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-210991	"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions"
XP_049793109.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049800888.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049813425.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049812333.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049794572.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049790467.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049789194.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049814204.1	7	Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2	"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis"
XP_049806936.1	20	MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7227;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7226	"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_049814410.1	3	KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17	"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism"
XP_049816854.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049811241.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_049813587.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049809172.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049815029.1	33	Reactome: R-HSA-69656;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-69202;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-77075	"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Cyclin E associated events during G1/S transition";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_049792205.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049796202.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049812959.1	12	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_049802299.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859	"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly"
XP_049793143.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049793765.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049806868.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049788885.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049809702.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049807368.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049805159.1	5	KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3	"Folate biosynthesis";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"One carbon pool by folate"
XP_049801930.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049792142.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Alanine racemization"
XP_049791498.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_049801177.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049790466.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049807507.1	9	MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18	"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione metabolism"
XP_049811503.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049788744.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049805392.1	24	Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-392851	"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G alpha (q) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor"
XP_049796932.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_049815129.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049805020.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049808187.1	4	MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_049803876.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049812206.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_049808870.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-349425	"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049799155.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049814487.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_049789117.1	5	KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3	"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism"
XP_049793069.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793498.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049795471.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049790698.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049811329.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049812545.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049805849.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049805613.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049808378.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800351.1	3	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_049809138.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
XP_049815725.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_049807254.1	14	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-7417	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049801683.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049812063.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007	"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)"
XP_049800989.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_049801573.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049799127.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049801845.1	6	Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049797404.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049792244.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049803530.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_049794135.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049816013.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria"
XP_049793496.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049806133.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049792187.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049811770.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049788988.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049816868.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049807998.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049799879.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049793020.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_049800357.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804160.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4"
XP_049805906.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049795166.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Neutrophil degranulation";"Signal transduction by L1";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes"
XP_049815127.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049801154.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049792800.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_049816859.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049809762.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049809470.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049798010.1	7	Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049815913.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049811608.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4"
XP_049808490.1	3	Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_049808952.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049813446.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091	"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching"
XP_049791910.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049809421.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049792823.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049805064.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049790767.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049809627.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049791499.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_049814453.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049807271.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049794029.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress"
XP_049803752.1	21	MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7219;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.3	"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism"
XP_049814603.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049810593.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_049809515.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_049810134.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049814063.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049813810.1	15	MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-8004	"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway I"
XP_049816053.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049801131.1	6	Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species"
XP_049793727.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049792905.1	7	KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-6351;MetaCyc: PWY-7625;Reactome: R-HSA-1483226	"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI"
XP_049812510.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049807388.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049792380.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_049812222.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049807048.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049802733.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859	"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly"
XP_049793689.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049805142.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049812532.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049800471.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049801839.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1	"Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_049814828.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049816242.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049796589.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049816527.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049793249.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049803139.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049791757.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_049792935.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5620924;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1632852	"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Intraflagellar transport";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Macroautophagy"
XP_049791203.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049799916.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049789317.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049814151.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049814200.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049801066.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049797108.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-9010553	"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs"
XP_049788525.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049812420.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049794076.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049792253.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049808422.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
XP_049812907.1	7	Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049792636.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049800452.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049801652.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049803055.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation"
XP_049815711.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049811876.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_049809636.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049808161.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_049809224.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049811817.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049788728.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049806295.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049800600.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049790182.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049807068.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049798880.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049801482.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049809620.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049808809.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049789978.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049795228.1	9	Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049792044.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049812995.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049793547.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176409	"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_049810760.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049796998.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049812783.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049797996.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049815119.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080	"Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)"
XP_049810628.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049812076.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049793852.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049812947.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049806841.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049808194.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049807672.1	16	Reactome: R-HSA-70263;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11	"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis"
XP_049804879.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049808658.1	19	Reactome: R-HSA-2408557;Reactome: R-HSA-3214858;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Selenocysteine synthesis";"RMTs methylate histone arginines";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Protein methylation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049815715.1	6	MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_049816764.1	3	KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism"
XP_049813085.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049805697.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049804166.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"HCMV Early Events";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins"
XP_049813445.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430	"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation"
XP_049793193.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816864.1	10	MetaCyc: PWY-3821;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-6317	"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)"
XP_049810230.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049806187.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049816335.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049801690.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049808300.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049800214.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049811819.1	4	Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane"
XP_049791300.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049792871.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"RAF activation";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated"
XP_049816109.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049803523.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049811197.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049811640.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049789845.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049800904.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049816213.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049814117.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049797689.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049802007.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049813488.1	9	Reactome: R-HSA-8853383;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00511+3.2.1.25	"Lysosomal oligosaccharide catabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Sphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Other glycan degradation"
XP_049809524.1	11	MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis II"
XP_049805050.1	10	KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742	"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Thermogenesis";"RSK activation";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"
XP_049808247.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049814149.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049815854.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049812839.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism"
XP_049795410.1	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events"
XP_049791184.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049804300.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_049807890.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049807550.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049808367.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807531.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049808815.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049812495.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049814930.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049796911.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049814372.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242	"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049813328.1	9	Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-69017;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049805930.1	2	KEGG: 00450+1.8.1.9;Reactome: R-HSA-499943	"Selenocompound metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049816230.1	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_049795110.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049791497.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_049801769.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_049807201.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_049804483.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049799904.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-975634	"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport"
XP_049809697.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049791547.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049801795.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049809349.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049810068.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049797641.1	15	MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Purine metabolism";"Entner-Doudoroff pathway I"
XP_049792106.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049807814.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049793064.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049811502.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049815673.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049811244.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722	"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis"
XP_049812993.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049809529.1	11	MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-2029485;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Anandamide biosynthesis II";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Role of phospholipids in phagocytosis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
XP_049791905.1	4	MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_049816677.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049810759.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049801045.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049803870.1	10	KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Ub-specific processing proteases";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_049792146.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism"
XP_049794134.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049811715.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049809642.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049799733.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049801169.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049799531.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049813178.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049790239.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049811146.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049801584.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049789064.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049805310.1	7	KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6121	"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049799764.1	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_049802636.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_049799694.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049792643.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049815145.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049799939.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049803296.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049808524.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Photosynthesis";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"ATP biosynthesis";"Insulin receptor recycling"
XP_049803484.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049816754.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049812008.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049801439.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049810909.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049805859.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049794370.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049809094.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049788764.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049816751.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049814495.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade"
XP_049807903.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-6782210;Reactome: R-HSA-110381;Reactome: R-HSA-5696397	"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049788942.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049794960.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049790586.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_049815080.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049793144.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049792189.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049802814.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049789098.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049791347.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049804011.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049814449.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049811258.1	15	Reactome: R-HSA-9652282;Reactome: R-HSA-9665251;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-9665245;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810	"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII"
XP_049793327.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049816711.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049813373.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-373753	"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Nephrin family interactions"
XP_049809631.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049815379.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049806326.1	29	Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-73772	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape"
XP_049812815.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049794981.1	9	MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049811261.1	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049812998.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_049807690.1	12	KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6613;Reactome: R-HSA-73817;Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism";"Purine metabolism"
XP_049793063.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049789588.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049799981.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049802773.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049794132.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049791011.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049791668.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049803189.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815551.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049799926.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049815401.1	4	Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_049797852.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049815941.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-2243919	"Laminin interactions";"Anchoring fibril formation";"Collagen degradation";"Extracellular matrix organization";"Integrin cell surface interactions";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"NCAM1 interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils"
XP_049802390.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049791418.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_049795578.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049798278.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481	"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints"
XP_049805299.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_049793340.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049813397.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049812049.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097	"DSCAM interactions";"p38MAPK events";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049802637.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5656169	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis"
XP_049811976.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049814565.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049788558.1	5	Reactome: R-HSA-1234158;Reactome: R-HSA-8951664;Reactome: R-HSA-1234174;Reactome: R-HSA-8849473;Reactome: R-HSA-1234176	"Regulation of gene expression by Hypoxia-inducible Factor";"Neddylation";"Cellular response to hypoxia";"PTK6 Expression";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049815480.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049798307.1	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Thermogenesis"
XP_049788618.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_049812516.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049813427.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049796245.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049810460.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049794200.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049810055.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049806143.1	14	MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-1622;KEGG: 00670+2.1.2.1	"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism";"Photorespiration ";"Glycine betaine degradation I";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Methane metabolism";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"One carbon pool by folate"
XP_049810666.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049794377.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_049802609.1	14	KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1	"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism"
XP_049799958.1	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation";"SUMOylation of DNA methylation proteins"
XP_049808794.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049804062.1	44	Reactome: R-HSA-450341;Reactome: R-HSA-375165;Reactome: R-HSA-2029482;Reactome: R-HSA-2559582;Reactome: R-HSA-445144;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9634638;Reactome: R-HSA-6802946;Reactome: R-HSA-982772;Reactome: R-HSA-2559580;Reactome: R-HSA-5654733;Reactome: R-HSA-6811558;Reactome: R-HSA-2559585;Reactome: R-HSA-6802948;Reactome: R-HSA-5674499;Reactome: R-HSA-6802955;Reactome: R-HSA-8939211;Reactome: R-HSA-2871796;Reactome: R-HSA-3371453;Reactome: R-HSA-879415;Reactome: R-HSA-1295596;Reactome: R-HSA-8943724;Reactome: R-HSA-112409;Reactome: R-HSA-198753;Reactome: R-HSA-9649948;Reactome: R-HSA-9627069;Reactome: R-HSA-5654726;Reactome: R-HSA-74749;Reactome: R-HSA-5675221;Reactome: R-HSA-6802952;Reactome: R-HSA-881907;Reactome: R-HSA-444257;Reactome: R-HSA-5663213;Reactome: R-HSA-170968;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-202670;Reactome: R-HSA-5674135;Reactome: R-HSA-162658;Reactome: R-HSA-8940973;Reactome: R-HSA-5673001;Reactome: R-HSA-5668599;Reactome: R-HSA-5654727;Reactome: R-HSA-9635465	"Activation of the AP-1 family of transcription factors";"NCAM signaling for neurite out-growth";"Regulation of actin dynamics for phagocytic cup formation";"Senescence-Associated Secretory Phenotype (SASP)";"Signal transduction by L1";"mTOR signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by moderate kinase activity BRAF mutants";"Growth hormone receptor signaling";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Oncogene Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ESR-mediated signaling";"FCERI mediated MAPK activation";"Regulation of HSF1-mediated heat shock response";"Advanced glycosylation endproduct receptor signaling";"Spry regulation of FGF signaling";"Regulation of PTEN gene transcription";"RAF-independent MAPK1/3 activation";"ERK/MAPK targets";"Signaling downstream of RAS mutants";"Regulation of the apoptosome activity";"Negative regulation of FGFR1 signaling";"Signal attenuation";"Negative regulation of MAPK pathway";"Signaling by BRAF and RAF fusions";"Gastrin-CREB signalling pathway via PKC and MAPK";"RSK activation";"RHO GTPases Activate WASPs and WAVEs";"Frs2-mediated activation";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"ERKs are inactivated";"MAP2K and MAPK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"RUNX2 regulates osteoblast differentiation";"RAF/MAP kinase cascade";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR2 signaling";"Suppression of apoptosis"
XP_049792898.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049803195.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049808215.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049809168.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049807160.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049800982.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049797994.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049808140.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
XP_049812024.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_049797776.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049805798.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_049789378.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049806226.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049791408.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049814057.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049792569.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049792787.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049790420.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049814896.1	12	KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_049808596.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049813042.1	8	MetaCyc: PWY-6133;MetaCyc: PWY-5394;Reactome: R-HSA-209905;MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2;KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049	"(S)-reticuline biosynthesis II";"Betalamic acid biosynthesis";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis";"Folate biosynthesis";"Tyrosine metabolism";"Rosmarinic acid biosynthesis II"
XP_049801285.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_049793095.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049807047.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049793588.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049792095.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049812927.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049800245.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049814594.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049813847.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2	"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway"
XP_049796890.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_049811262.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by Hippo"
XP_049809140.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049796709.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049801108.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049801101.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049806589.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049813523.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049789450.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049802485.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049794728.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049806578.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049807753.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_049805023.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049810590.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_049793531.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049802696.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049803174.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049805745.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049813489.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
XP_049801504.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049815363.1	7	Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796	"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_049801019.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049814970.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049809797.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049801220.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049808429.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049808549.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049816133.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049805312.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_049809150.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_049804041.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049812960.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049808560.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049791935.1	14	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2022377;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049788873.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049813175.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049800469.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049811107.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049797105.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism"
XP_049792771.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049802984.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_049812138.1	24	Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"G alpha (q) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049796889.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049804343.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049791621.1	15	Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes"
XP_049789753.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049813229.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049793087.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049805049.1	10	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Relaxin signaling pathway";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"RSK activation";"PI3K-Akt signaling pathway"
XP_049791213.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049814894.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5873;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_049792276.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049808097.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049810651.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_049815190.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049790459.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_049791911.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049797099.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649	"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation"
XP_049815329.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049813001.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049794353.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049815288.1	8	MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway I";"Cholesterol biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_049798846.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049809750.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049813376.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Neutrophil degranulation";"COPII-mediated vesicle transport"
XP_049797957.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049801535.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049813422.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049807509.1	9	KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II"
XP_049815825.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049816781.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_049811779.1	8	KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27	"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism"
XP_049812805.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_049791849.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049793542.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049802056.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049812478.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049815277.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_049801141.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049793501.1	15	Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends"
XP_049790835.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049788522.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049814443.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049795159.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_049801747.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049815098.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049805610.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049813382.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049799937.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049801140.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049803961.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4041	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle"
XP_049812665.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049788671.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049814112.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049811882.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049816209.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_049813318.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049792853.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049790340.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049799941.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049812048.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049794827.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049790685.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_049813447.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411	"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere"
XP_049791059.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049791156.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049814284.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049793853.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049815078.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049814664.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049808585.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_049814991.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049805003.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049804664.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-9656256;Reactome: R-HSA-9656255;Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-5649702;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049806648.1	6	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_049797643.1	15	MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Purine metabolism";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)"
XP_049800355.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815731.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_049815008.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049807806.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049809114.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049808278.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049811867.1	4	Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_049809851.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state";"PKA activation in glucagon signalling"
XP_049792381.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_049797623.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049801503.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049815358.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049788519.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049805561.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049801148.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049793538.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802310.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049808499.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049816134.1	18	MetaCyc: PWY-6545;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;Reactome: R-HSA-5624138;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7205	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Trafficking of myristoylated proteins to the cilium";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation"
XP_049802539.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049795402.1	6	KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1	"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049802535.1	3	MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049807433.1	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_049801746.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049816865.1	10	MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-3821	"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification"
XP_049802251.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049813025.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049809773.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049793173.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049807678.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049812881.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805709.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049793174.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049811619.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397	"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049788886.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_049808237.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049793961.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049790546.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049795639.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847	"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones"
XP_049789692.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049811778.1	8	MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_049806531.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049794002.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049812890.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_049792788.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049789510.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049815833.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049807824.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049809262.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049810792.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049810207.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049803689.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049815830.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049810425.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049797775.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049813239.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-203754	"Protein ubiquitination";"NOSIP mediated eNOS trafficking"
XP_049799078.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049808548.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049790330.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049796449.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049812180.1	8	MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943;MetaCyc: PWY-7197	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_049805378.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049805198.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049814614.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049797962.1	1	Reactome: R-HSA-156581	"Methylation"
XP_049807420.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6783310;Reactome: R-HSA-606279	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049805787.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049813824.1	8	KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1	"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism"
XP_049812372.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049810526.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049812663.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049805790.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049791645.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-8873719	"TBC/RABGAPs";"RAB geranylgeranylation"
XP_049802701.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049805846.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049802156.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049801123.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049808465.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049788946.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_049806856.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049805146.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049814392.1	4	KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049803491.1	18	MetaCyc: PWY-7416;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC"
XP_049812443.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379	"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"HCMV Late Events"
XP_049802042.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049811748.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049814171.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049813325.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049805273.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049797098.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism"
XP_049807929.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049813256.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_049801695.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation"
XP_049801077.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049800840.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049814497.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_049813011.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049792363.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049795403.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049799117.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049802467.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049807228.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049800522.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049813535.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049804606.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049814901.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049802001.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049807432.1	3	KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262;MetaCyc: PWY-6100	"Lysine degradation";"Carnitine synthesis";"L-carnitine biosynthesis"
XP_049804491.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049807972.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049807622.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049800688.1	4	KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
XP_049801271.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6	"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism"
XP_049797969.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_049793207.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793582.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-110362	"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair"
XP_049790530.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049800112.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049800169.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049790695.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049807797.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049801426.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049806830.1	15	Reactome: R-HSA-9652282;Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665245;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810	"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII"
XP_049793280.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049812371.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_049809863.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049808550.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049807004.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049791754.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_049811382.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049814154.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049808124.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049789517.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049802116.1	7	Reactome: R-HSA-5689603;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-171319;Reactome: R-HSA-5696394	"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases";"HATs acetylate histones";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER"
XP_049811552.1	3	MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099	"L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling"
XP_049801932.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049801263.1	40	Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-76042;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167158	"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex"
XP_049804451.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049802705.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_049803524.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049795532.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-8086;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049797955.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_049793468.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049806612.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049804005.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049814942.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049788552.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049811345.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049793106.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049793102.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049800842.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049815231.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049813711.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049791704.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049815843.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049804947.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049808505.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049815292.1	8	Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
XP_049791866.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049797516.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049813454.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858	"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II"
XP_049809397.1	11	Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrogen metabolism"
XP_049812574.1	6	KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane"
XP_049801767.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_049793701.1	12	Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6683	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Purine metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III"
XP_049789103.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049805536.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049804532.1	24	KEGG: 04150+2.7.11.11;Reactome: R-HSA-9010642;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-9634600;Reactome: R-HSA-432040;Reactome: R-HSA-163358;Reactome: R-HSA-8853659;Reactome: R-HSA-392517;Reactome: R-HSA-163560;Reactome: R-HSA-180024;Reactome: R-HSA-5610785;Reactome: R-HSA-422356;Reactome: R-HSA-442720;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-8963896;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-111931;Reactome: R-HSA-4420097;Reactome: R-HSA-5621575;Reactome: R-HSA-163615	"mTOR signaling pathway";"ROBO receptors bind AKAP5";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA-mediated phosphorylation of key metabolic factors";"RET signaling";"Rap1 signalling";"Triglyceride catabolism";"DARPP-32 events";"GLI3 is processed to GLI3R by the proteasome";"Regulation of insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"HDL assembly";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA-mediated phosphorylation of CREB";"VEGFA-VEGFR2 Pathway";"CD209 (DC-SIGN) signaling";"PKA activation"
XP_049804065.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049792934.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049795145.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-4661;MetaCyc: PWY-6365;MetaCyc: PWY-6362;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6366;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol"
XP_049788575.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049793171.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049793120.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049811242.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_049816631.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_049802293.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049802946.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049789035.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport"
XP_049803181.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049791763.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049806833.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049792880.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049804051.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049811372.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_049805994.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049810409.1	11	Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049802649.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-174178	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Neddylation";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049789315.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049815376.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049810096.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049816143.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049809962.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167242	"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049816902.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049805002.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049793337.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049813466.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049797656.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis"
XP_049811480.1	10	KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_049791087.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049788872.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049804401.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049793543.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049790677.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049791706.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_049792719.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049809701.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049808497.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049809963.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_049800635.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049807654.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159227	"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA"
XP_049805266.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049808137.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
XP_049811737.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049801789.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049811939.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_049804892.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049800411.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049813635.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049809126.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049789627.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049810358.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_049815631.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049804054.1	7	MetaCyc: PWY-4984;MetaCyc: PWY-31;MetaCyc: PWY-46;Reactome: R-HSA-70635;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1	"Urea cycle";"Canavanine degradation";"Putrescine biosynthesis III";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine biosynthesis"
XP_049812007.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049812176.1	8	Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7210	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049792328.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049814759.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"