Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_049942402.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049941799.1	10	MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_049956622.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049939998.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049956456.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049944683.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_049950141.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_049943046.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049958602.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049963321.1	7	Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
XP_049941753.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049961847.1	18	MetaCyc: PWY-7197;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7224;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_049964652.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049938733.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_049953961.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049946453.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049957794.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954305.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049942201.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049963465.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049938150.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049943425.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049964815.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049953310.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049953299.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049947316.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049949151.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_049960130.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049952888.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049943152.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049950707.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049963845.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049949516.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049945958.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049941683.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049960289.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049950869.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
XP_049963500.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049943110.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049938991.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049946113.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049937282.1	8	MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061	"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I"
XP_049952380.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7338	"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_049962878.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049964467.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049942030.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049961771.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049949154.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_049945207.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049961420.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049961532.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049963876.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049959066.1	5	Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94	"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_049938339.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049960118.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_049964749.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_049954199.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049963164.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049950677.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_049963211.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_049956133.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049956605.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953742.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049948632.1	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
XP_049960780.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154	"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin"
XP_049952567.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049940615.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049953289.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049949245.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049942910.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049948226.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049955702.1	5	Reactome: R-HSA-5668599;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756	"RHO GTPases Activate NADPH Oxidases";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation"
XP_049938071.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis"
XP_049955854.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049960480.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049952889.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism"
XP_049937659.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049942345.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049952105.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049962082.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049964605.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049946464.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049960779.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049962213.1	8	KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1	"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis"
XP_049938878.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049946185.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049939498.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049956664.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049951830.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049957509.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049953897.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049955734.1	3	Reactome: R-HSA-71262;MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8	"Carnitine synthesis";"L-carnitine biosynthesis";"Lysine degradation"
XP_049962245.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049938396.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049946581.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049958340.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049953556.1	19	Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-163765;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;Reactome: R-HSA-75105	"Neutrophil degranulation";"Propanoate metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis"
XP_049959401.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_049951725.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049955094.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049956702.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Synthesis of PA"
XP_049959377.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049961582.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049960869.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049955793.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049954592.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049940449.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation"
XP_049945973.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049940057.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049941540.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049964159.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049955427.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_049951487.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049963506.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049957415.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049947665.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049944676.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-450408	"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049958561.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049955296.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049957118.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
XP_049961529.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049940050.1	7	Reactome: R-HSA-4549356;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;MetaCyc: PWY-5265	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)"
XP_049951856.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049962164.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049963118.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049939487.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049959141.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049964479.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049959323.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049962702.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049937853.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049962051.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049963752.1	58	MetaCyc: PWY-7216;Reactome: R-HSA-77288;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7726;MetaCyc: PWY-7656;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6863;Reactome: R-HSA-77346;KEGG: 00930+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-5136;MetaCyc: PWY-5177;KEGG: 00280+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;MetaCyc: PWY-5789;MetaCyc: PWY-1361;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;Reactome: R-HSA-77310;Reactome: R-HSA-77305;KEGG: 00062+4.2.1.17+1.1.1.211;Reactome: R-HSA-77350;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35	"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Tryptophan metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to hexanol (engineered)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Caprolactam degradation";"Toluene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid beta-oxidation II (plant peroxisome)";"Glutaryl-coa degradation";"Valine, leucine and isoleucine degradation";"Acyl chain remodeling of CL";"Caprolactam degradation";"Aminobenzoate degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Butanoate metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoyl-coa degradation I (aerobic)";"Phenylalanine metabolism";"Butanoate metabolism";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"Carbon fixation pathways in prokaryotes";"Androstenedione degradation";"alpha-Linolenic acid metabolism";"Lysine degradation";"Geraniol degradation";"Fatty acid salvage";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid elongation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"beta-Alanine metabolism";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Lysine degradation"
XP_049960057.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049943958.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_049963261.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049950961.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049962339.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825	"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049953993.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049958938.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049960833.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_049949289.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049940599.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049959453.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049957438.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049947524.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049943173.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049961301.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049941756.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049945755.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism"
XP_049952882.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_049950013.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_049959204.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049941924.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049955214.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_049953212.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049951636.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049940364.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-73614;MetaCyc: PWY-7199;KEGG: 00983+2.7.1.21;KEGG: 00240+2.7.1.21	"G1/S-Specific Transcription";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049949281.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049949816.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049962175.1	15	Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9665251;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282	"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling"
XP_049954249.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-6453	"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis"
XP_049950127.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049953771.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049957564.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_049938233.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049943278.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049954459.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049951576.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049952707.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049937356.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049962498.1	5	MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)"
XP_049953545.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049949405.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049950866.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs"
XP_049948614.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049958458.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941746.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049941489.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049955474.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049942519.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940141.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049950871.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049954894.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049938626.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049949095.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585	"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Hedgehog 'on' state";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G"
XP_049942923.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940394.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049956719.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049958631.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049958423.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049938855.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681	"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling"
XP_049943614.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960194.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049938321.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580	"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence"
XP_049964840.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_049964122.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049938350.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination"
XP_049961300.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049944067.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780	"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome"
XP_049940586.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049956625.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049938706.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049943915.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049948617.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049957414.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049963149.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049962313.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049948475.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049961231.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049960262.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049964717.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_049953776.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049941918.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049959017.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049955375.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049954799.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049948840.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;MetaCyc: PWY-7221	"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis"
XP_049961175.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049954583.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049944092.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049959273.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049964608.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_049950913.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049961624.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049954062.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049959458.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049943950.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049949217.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism"
XP_049943856.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049952071.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_049960916.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049959596.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049953441.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_049962995.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049955828.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_049956424.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049941036.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6798695;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Neutrophil degranulation";"Th1 and Th2 cell differentiation"
XP_049950773.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_049938764.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_049937506.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049954252.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III"
XP_049951876.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049955726.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049959995.1	13	MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-6613	"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations I";"Folate polyglutamylation";"Metabolism of folate and pterines";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_049952080.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049943921.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049957992.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049939848.1	14	Reactome: R-HSA-434316;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;Reactome: R-HSA-500657;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-418217;Reactome: R-HSA-416476;MetaCyc: PWY-8052	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Acetylcholine regulates insulin secretion";"Ca2+ pathway";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis"
XP_049960237.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria"
XP_049938807.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049957737.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049938482.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168	"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)"
XP_049950530.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049962499.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_049962214.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049943086.1	7	MetaCyc: PWY-7782;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-3385	"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Glycerophospholipid metabolism";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I"
XP_049951626.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_049953075.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049954567.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049957609.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_049960720.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049950471.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049949519.1	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049951321.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049938246.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049951906.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049943334.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049958654.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049942303.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049937961.1	7	MetaCyc: PWY-7854;MetaCyc: PWY-6969;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"Chitin degradation to ethanol";"Pyruvate metabolism";"L-arabinose degradation IV"
XP_049958449.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049953800.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049964750.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_049958121.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049962278.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049954408.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049952068.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049958074.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049958138.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_049951682.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049939011.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049943812.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049963272.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5870;KEGG: 00130+1.14.99.60	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049955785.1	5	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway"
XP_049950442.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049956621.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049955910.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049938085.1	29	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-167152	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_049954582.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952809.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049951290.1	58	Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689901;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154	"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Metalloprotease DUBs";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin"
XP_049958935.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049948938.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049951180.1	11	MetaCyc: PWY-8052;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4	"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_049964864.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049948412.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis"
XP_049952503.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049950855.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_049939431.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049953390.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049964447.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049959374.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049940777.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049956665.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049950326.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049955321.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049962868.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049961308.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049959958.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7279	"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_049955107.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049959807.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_049961774.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049962542.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049962874.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049961431.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961641.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049956528.1	26	Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-1234158;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947	"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Circadian Clock";"Estrogen-dependent gene expression";"PPARA activates gene expression";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049962515.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-882	"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_049963988.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049937409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049941209.1	44	Reactome: R-HSA-445144;Reactome: R-HSA-6802955;Reactome: R-HSA-5654726;Reactome: R-HSA-5668599;Reactome: R-HSA-5654727;Reactome: R-HSA-6802946;Reactome: R-HSA-6811558;Reactome: R-HSA-9634638;Reactome: R-HSA-879415;Reactome: R-HSA-5663213;Reactome: R-HSA-3371453;Reactome: R-HSA-170968;Reactome: R-HSA-9627069;Reactome: R-HSA-8939211;Reactome: R-HSA-2559580;Reactome: R-HSA-112409;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-5654732;Reactome: R-HSA-375165;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-8940973;Reactome: R-HSA-6802952;Reactome: R-HSA-1295596;Reactome: R-HSA-2559582;Reactome: R-HSA-9649948;Reactome: R-HSA-982772;Reactome: R-HSA-202670;Reactome: R-HSA-2871796;Reactome: R-HSA-444257;Reactome: R-HSA-162658;Reactome: R-HSA-2029482;Reactome: R-HSA-74749;Reactome: R-HSA-9635465;Reactome: R-HSA-5675221;Reactome: R-HSA-2559585;Reactome: R-HSA-881907;Reactome: R-HSA-5674499;Reactome: R-HSA-198753;Reactome: R-HSA-6802948;Reactome: R-HSA-5654733;Reactome: R-HSA-5673001;Reactome: R-HSA-456926	"Signal transduction by L1";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of FGFR1 signaling";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR2 signaling";"Signaling by moderate kinase activity BRAF mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Advanced glycosylation endproduct receptor signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of HSF1-mediated heat shock response";"Frs2-mediated activation";"Regulation of the apoptosome activity";"ESR-mediated signaling";"Oxidative Stress Induced Senescence";"RAF-independent MAPK1/3 activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR3 signaling";"NCAM signaling for neurite out-growth";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"RUNX2 regulates osteoblast differentiation";"Signaling by BRAF and RAF fusions";"Spry regulation of FGF signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling downstream of RAS mutants";"Growth hormone receptor signaling";"ERKs are inactivated";"FCERI mediated MAPK activation";"RSK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of actin dynamics for phagocytic cup formation";"Signal attenuation";"Suppression of apoptosis";"Negative regulation of MAPK pathway";"Oncogene Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative feedback regulation of MAPK pathway";"ERK/MAPK targets";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR4 signaling";"RAF/MAP kinase cascade";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049958888.1	6	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049947008.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_049963518.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049957436.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049960440.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049960406.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049947953.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049940505.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049961889.1	8	KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086	"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_049944835.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049956779.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049955953.1	4	KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049949366.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049940747.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_049954734.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049951934.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_049956867.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-191859	"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"snRNP Assembly"
XP_049941922.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049952125.1	6	KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17	"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism"
XP_049961131.1	12	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-5250924	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression"
XP_049956660.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049947681.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049956936.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049955134.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049941104.1	4	Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-198693	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus"
XP_049938518.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049953971.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049960931.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049944058.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049954258.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049955098.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049948253.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049957789.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940581.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049962936.1	13	MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-7659	"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis"
XP_049942100.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049963267.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_049940216.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_049955476.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049954812.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049961010.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049955479.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049945111.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049960415.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049942306.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049961566.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049952861.1	7	MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25	"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch degradation V";"Starch and sucrose metabolism"
XP_049958922.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049957791.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937945.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049960171.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049952062.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049937309.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049962904.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049964352.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049939971.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941909.1	18	MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4	"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism"
XP_049953306.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_049946479.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049958075.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049940503.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049962299.1	9	KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6470;MetaCyc: PWY-6385;MetaCyc: PWY-5265;Reactome: R-HSA-446193	"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049940326.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049951185.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_049946207.1	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049957136.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049938076.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049950473.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049956312.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049961524.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049953901.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049941109.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049959563.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_049949972.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9630222	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding"
XP_049964602.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049939305.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049958223.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049944804.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049946590.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049960376.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049955418.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049937987.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960150.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049949738.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049951071.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049950061.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049956728.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049959050.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049954067.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049950286.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_049942344.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_049957130.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695	"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation"
XP_049957805.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049959795.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049942762.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049958768.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049943574.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049956654.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049960279.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049938800.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049941573.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049938346.1	13	Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-182218	"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation"
XP_049940680.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049937454.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049944156.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049950693.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049958124.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049940420.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049942101.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049950016.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049951765.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253	"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_049950680.1	17	KEGG: 04926+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-1221632;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5685938;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"Meiotic synapsis";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Single Strand Annealing (SSA)";"mTOR signaling pathway";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis"
XP_049948890.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_049942167.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049942229.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049956070.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
XP_049940104.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_049951082.1	7	KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686;MetaCyc: PWY-7790;Reactome: R-HSA-500753	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine biosynthesis"
XP_049960688.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049956649.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049952274.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049948210.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes"
XP_049962927.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049939967.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049960710.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049945573.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_049942062.1	10	Reactome: R-HSA-168179;Reactome: R-HSA-1236974;Reactome: R-HSA-5603041;Reactome: R-HSA-5602498;Reactome: R-HSA-9637628;Reactome: R-HSA-1461957;Reactome: R-HSA-6798695;Reactome: R-HSA-5686938;Reactome: R-HSA-166058;Reactome: R-HSA-168188	"Toll Like Receptor TLR1:TLR2 Cascade";"ER-Phagosome pathway";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR2/4)";"Modulation by Mtb of host immune system";"Beta defensins";"Neutrophil degranulation";"Regulation of TLR by endogenous ligand";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Toll Like Receptor TLR6:TLR2 Cascade"
XP_049940905.1	4	MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_049955511.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049962328.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049937308.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23	"Neutrophil degranulation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Galactose metabolism";"HS-GAG degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049956607.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049955589.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049955268.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049954882.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049941558.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049948907.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049961994.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049961208.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049942105.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049937904.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049963455.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049959263.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049946360.1	9	MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_049956001.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939	"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)"
XP_049950804.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049964657.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049941899.1	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_049959018.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049962367.1	8	MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates"
XP_049959421.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049954160.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049942420.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_049961512.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049950694.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049955780.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049956094.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049963895.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_049949061.1	6	MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Pentose phosphate pathway"
XP_049948351.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049964804.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_049956637.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049956708.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049951311.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049960317.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049946183.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049945400.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049963205.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049963453.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049954270.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049961722.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049954709.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049949495.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049950487.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049960179.1	20	KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6	"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation"
XP_049960379.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172	"NOD1/2 Signaling Pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"DSCAM interactions"
XP_049941431.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049940922.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_049946163.1	4	Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049940281.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049944749.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049963815.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049950381.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049944764.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049951863.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049950033.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049950926.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049948378.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961797.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049946169.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_049964660.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049939180.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049964194.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049956642.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_049937734.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_049950342.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049941132.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049954736.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049942208.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049959452.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049952230.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_049960090.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049939805.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049947155.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049964482.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049960348.1	12	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476	"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"DCC mediated attractive signaling";"Relaxin signaling pathway";"G alpha (q) signalling events"
XP_049938081.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049960995.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_049948579.1	5	MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;MetaCyc: PWY-5668;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Synthesis of PG"
XP_049962438.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_049963005.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049963877.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;MetaCyc: PWY-7511	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination"
XP_049940146.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049949339.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049949230.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-2151201	"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis"
XP_049957600.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049958064.1	29	Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395	"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER"
XP_049954093.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_049962740.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049937438.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049955843.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049957505.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049941554.1	14	Reactome: R-HSA-6798695;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507	"Neutrophil degranulation";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049956230.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049948414.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_049939204.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049949432.1	4	KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049960912.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049961859.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049947335.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049960235.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_049963215.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049961457.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540	"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1"
XP_049956812.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049942400.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Selenoamino acid metabolism"
XP_049946274.1	4	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism"
XP_049939477.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049962427.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049937822.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049938390.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049954232.1	6	MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049955939.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049955293.1	5	MetaCyc: PWY-5531;MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_049937596.1	7	MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31;Reactome: R-HSA-71336;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004	"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Pentose phosphate pathway";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I"
XP_049958259.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961109.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_049963384.1	13	KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation"
XP_049957248.1	13	Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227	"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_049942301.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049959270.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_049961729.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049951894.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049947151.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049952769.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049963190.1	33	Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-68877	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase"
XP_049951513.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049952564.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049946160.1	1	Reactome: R-HSA-156581	"Methylation"
XP_049961433.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951322.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049942650.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049960697.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049950337.1	6	Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis"
XP_049953855.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_049952316.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955845.1	5	Reactome: R-HSA-1234158;Reactome: R-HSA-8849473;Reactome: R-HSA-1234174;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664	"Regulation of gene expression by Hypoxia-inducible Factor";"PTK6 Expression";"Cellular response to hypoxia";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation"
XP_049938470.1	5	Reactome: R-HSA-73614;MetaCyc: PWY-7181;KEGG: 00240+2.4.2.4;KEGG: 00983+2.4.2.4;Reactome: R-HSA-73621	"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_049959222.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049937385.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049956098.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049939949.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_049939520.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_049958931.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049950128.1	13	MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6969	"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049963725.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049941592.1	12	KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13	"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methane metabolism"
XP_049956382.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952804.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049941731.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049942587.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953661.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging"
XP_049957914.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049942290.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049937820.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049957071.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049955213.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75955	"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation"
XP_049959615.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049947836.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049937486.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049953309.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049952253.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C"
XP_049938746.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049950897.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049957325.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049946173.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049938079.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-69017	"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6"
XP_049963497.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_049950055.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049940919.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049953853.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049954248.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053	"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II"
XP_049940605.1	10	Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-9648895;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049953695.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049962797.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049939173.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049949137.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_049948277.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_049937334.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-6782210	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049961738.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049943039.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049945672.1	4	Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_049939494.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049951948.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_049943285.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049945563.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049946634.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_049954324.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049963818.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049950664.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049959433.1	7	KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2	"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism"
XP_049950307.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049957610.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049963398.1	4	Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_049949465.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049962066.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049953447.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049944211.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049960176.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7291	"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_049949338.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049955262.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Kinesins";"Cilium Assembly";"COPI-mediated anterograde transport"
XP_049954850.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049939868.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049948497.1	32	Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-77075	"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_049947071.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049953049.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049938311.1	4	KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049962356.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_049963574.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049958318.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946	"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Meiotic synapsis";"Cohesin Loading onto Chromatin"
XP_049951351.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_049962643.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Kinesins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_049950330.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049941796.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049940674.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049952883.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_049950887.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049939895.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049955698.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049945256.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049937716.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049951241.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049943687.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049963233.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049964046.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049949362.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049951775.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049954348.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049961594.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049938031.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
YP_010417140.1	7	MetaCyc: PWY-3781;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-4302	"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Complex I biogenesis";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)"
XP_049959900.1	52	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-72203;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-749476;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-112382	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex"
XP_049952691.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049941260.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049946177.1	9	MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049952123.1	6	MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17	"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation"
XP_049949132.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049941597.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049939255.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049963327.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049964878.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049961364.1	3	KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17	"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism"
XP_049938320.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580	"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence"
XP_049960373.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049953210.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049962298.1	9	Reactome: R-HSA-5633231;KEGG: 00510+2.4.1.141;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6470;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6385	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis III (mycobacteria)"
XP_049947723.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049951406.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049947297.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049955264.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049964708.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725	"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049951182.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049957977.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049950332.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049963339.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049943180.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-110362	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair"
XP_049953235.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049955608.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_049961330.1	8	KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"Pentose phosphate pathway"
XP_049946520.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921	"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation"
XP_049962929.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049962423.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049941621.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049953124.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87	"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis"
XP_049959901.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_049961486.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049946593.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049942546.1	10	KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7391	"Butanoate metabolism";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)"
XP_049937362.1	10	MetaCyc: PWY-4321;MetaCyc: PWY-6535;KEGG: 00410+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6537;MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19	"L-glutamate degradation IV";"4-aminobutanoate degradation I";"beta-Alanine metabolism";"Degradation of GABA";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II";"4-aminobutanoate degradation V";"Propanoate metabolism";"Butanoate metabolism"
XP_049956362.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049949404.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049939903.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049944349.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594	"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events"
XP_049942417.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049940444.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049960230.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6807505	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes"
XP_049960144.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049954367.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049941148.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7338	"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_049962674.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_049952563.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049945754.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049953984.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049946457.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049961248.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049948457.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788	"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling"
XP_049963442.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"HCMV Early Events";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049950715.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049941679.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938	"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)"
XP_049942536.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049953879.1	7	Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-114608	"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation"
XP_049945927.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-1445148	"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Cilium Assembly";"Kinesins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049958939.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049959896.1	8	Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049951904.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049953763.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049964156.1	13	Reactome: R-HSA-8876725;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-532668;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371511	"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Josephin domain DUBs";"Aggrephagy";"HSF1 activation"
XP_049938810.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049937376.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049962045.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049954404.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049959150.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-180024	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"DARPP-32 events"
XP_049946164.1	4	Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049954043.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Tryptophan catabolism"
XP_049948053.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049957613.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049948576.1	5	MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5	"Cardiolipin biosynthesis I";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism"
XP_049958822.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation"
XP_049954333.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049939661.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049941432.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_049961710.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis"
XP_049943407.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049961628.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049954081.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049950790.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049941023.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049964861.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049953511.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049942488.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049937636.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049957323.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952082.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049942353.1	12	KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932	"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Selenate reduction"
XP_049946456.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049961055.1	4	Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049950958.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049958317.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519	"Meiotic synapsis";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression"
XP_049943002.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049937537.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049940133.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049960248.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049945683.1	11	Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"Ub-specific processing proteases";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049950655.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049938139.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8854214	"RAB geranylgeranylation";"TBC/RABGAPs"
XP_049952243.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049950258.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049960318.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049958372.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049954366.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049948580.1	5	MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;MetaCyc: PWY-5668;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Synthesis of PG"
XP_049962715.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049953834.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049956574.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049952070.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049960357.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049955325.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049947305.1	9	Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_049958027.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937508.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;Reactome: R-HSA-73817	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_049954159.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049956788.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_049953094.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049941596.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049942232.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049960714.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049938633.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049937788.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I"
XP_049953690.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049959369.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049952506.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_049950364.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049962601.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_049940708.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049959379.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049950527.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049937456.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049950642.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049939896.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049956781.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049949239.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049948496.1	32	Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-77075	"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_049957540.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049961064.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68952	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching";"DNA replication initiation"
XP_049958851.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-936837	"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Long-term potentiation";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases"
XP_049937302.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_049964723.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049952719.1	12	KEGG: 00620+2.3.3.9;MetaCyc: PWY-6728;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-7295;MetaCyc: PWY-6969;MetaCyc: PWY-5744;MetaCyc: PWY-7854;MetaCyc: PWY-7294	"Pyruvate metabolism";"Methylaspartate cycle";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"D-xylose degradation IV"
XP_049963473.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049964095.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049950036.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049948188.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049939806.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049956726.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049962651.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_049949578.1	5	Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-446388;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"Rho GTPase cycle"
XP_049959855.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049960100.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049962370.1	8	MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049956402.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049938421.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049956529.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049941625.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049939955.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049950645.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049958913.1	19	Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-936837	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases"
XP_049952847.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049953643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049941173.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049941322.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049959533.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049959136.1	33	Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-159231	"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049957045.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049940302.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049959943.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049938336.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049939596.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049959565.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_049950960.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049937741.1	9	Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-7039	"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule"
XP_049950250.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049951645.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049949954.1	7	MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation"
XP_049962998.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_049963556.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049963700.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049949138.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_049963359.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049955392.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049940354.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049962802.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049960050.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049942153.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049952168.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049955771.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049956627.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049953693.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049939185.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049940165.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049937739.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049960972.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049964072.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049955715.1	5	Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555	"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation"
XP_049954523.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049937879.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049957714.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049962689.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049937695.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049943172.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049950370.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_049939573.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_049938149.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049953331.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049954236.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049939644.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049961000.1	9	KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-6983;MetaCyc: PWY-6147	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I"
XP_049963715.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049942136.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_049949461.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049937847.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049955565.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049944684.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs"
XP_049951728.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954407.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049963704.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049940583.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049949952.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659	"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis"
XP_049958549.1	18	MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383	"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049946931.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049940065.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049938632.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy"
XP_049939391.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport"
XP_049944526.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;MetaCyc: PWY-7511	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination"
XP_049950421.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049940833.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049937827.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049963206.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049943627.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049949815.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049941816.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_049956311.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049960170.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049948886.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049949520.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049956891.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049963857.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_049955276.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049962428.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes"
XP_049960994.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_049960870.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049954326.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_049963820.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_049937418.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049950449.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049947145.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049946178.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_049959863.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049956228.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049963674.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049949545.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049963963.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_049956093.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049950348.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049937420.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049957954.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049943198.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_049964752.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_049950786.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049960380.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24	"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"mTOR signaling pathway"
XP_049941736.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049952974.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049962292.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049955301.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049953725.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_049960155.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049955895.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049948605.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787	"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'off' state"
XP_049957093.1	57	Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702	"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling"
XP_049956236.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049959336.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049960403.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049956075.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_049951732.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049942203.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_049946093.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-6886	"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Glycolysis";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)"
XP_049960316.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049963649.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049952674.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049942399.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism"
XP_049961327.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049963360.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_049938782.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_049954469.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection"
XP_049952887.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049950375.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_049950876.1	4	MetaCyc: PWY-5028;KEGG: 00340+3.5.2.7;Reactome: R-HSA-70921;MetaCyc: PWY-5030	"L-histidine degradation II";"Histidine metabolism";"Histidine catabolism";"L-histidine degradation III"
XP_049943416.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049959548.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049961147.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049953073.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_049942129.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049956653.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-68877	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase"
XP_049948667.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049947840.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049954323.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049956578.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049950304.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049963621.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_049950490.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049942911.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049955659.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"HIV Transcription Initiation"
XP_049942231.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049953070.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049953120.1	33	Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159236	"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049955116.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere"
XP_049939536.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049947387.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049963716.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049964795.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Ca2+ pathway"
XP_049951153.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_049941561.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049964767.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049941396.1	6	MetaCyc: PWY-922;KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_049960876.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049941271.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_049947330.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049960227.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049937555.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049953431.1	8	MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740	"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis"
XP_049963463.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049952890.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049963739.1	3	Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50	"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_049952031.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_049953875.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"RAF/MAP kinase cascade";"Neutrophil degranulation"
XP_049951865.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049938693.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049945753.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049951986.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049947198.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959811.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_049949515.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049949124.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852	"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy"
XP_049958175.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403	"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)"
XP_049948577.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;Reactome: R-HSA-1483148	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Synthesis of PG"
XP_049953994.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_049950929.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049952791.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049958333.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049938095.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360	"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_049962050.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049940508.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-162594	"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_049944147.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049953383.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049950917.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049958274.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049960591.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049956097.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049963571.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940208.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049954817.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049940623.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_049950827.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049938721.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049958611.1	10	MetaCyc: PWY-8067;MetaCyc: PWY-6839;MetaCyc: PWY-7510;MetaCyc: PWY-6682;MetaCyc: PWY-6322;MetaCyc: PWY-7769;KEGG: 00998+5.4.2.9;MetaCyc: PWY-5757;MetaCyc: PWY-7419;KEGG: 00440+5.4.2.9	"Methylphosphonate biosynthesis";"2-aminoethylphosphonate biosynthesis";"Rhizocticin A and B biosynthesis";"Dehydrophos biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Phosalacine biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Fosfomycin biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Phosphonate and phosphinate metabolism"
XP_049957155.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049937701.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049959380.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049956881.1	3	Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_049943217.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049940056.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049944320.1	5	MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20	"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Carbon fixation pathways in prokaryotes"
XP_049960099.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049953778.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049961004.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049958477.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049962703.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049937976.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049952424.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049955650.1	5	MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism"
XP_049946591.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049950472.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049952844.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049941126.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins"
XP_049959737.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049954906.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-202733	"Platelet sensitization by LDL";"Chylomicron remodeling";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"VLDL assembly";"Scavenging by Class H Receptors";"VLDL clearance";"Chylomicron assembly";"Scavenging by Class F Receptors";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall"
XP_049940396.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049950837.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_049937639.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049952124.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165	"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049956291.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049955631.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049958936.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049948610.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-182218	"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation"
XP_049948387.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049956083.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_049960404.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049962218.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049956854.1	3	Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_049960577.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049953125.1	4	Reactome: R-HSA-4755609;MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049946088.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049951879.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049963558.1	8	KEGG: 00790+4.1.99.22;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-947581;Reactome: R-HSA-5693571;MetaCyc: PWY-6823	"Folate biosynthesis";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Molybdenum cofactor biosynthesis";"Nonhomologous End-Joining (NHEJ)";"Molybdenum cofactor biosynthesis"
XP_049942918.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049956525.1	24	KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-444257;Reactome: R-HSA-392451;Reactome: R-HSA-389357;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;Reactome: R-HSA-165158	"Human papillomavirus infection";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"RSK activation";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"Activation of AKT2"
XP_049958342.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049958370.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_049950648.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049954671.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049960854.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_049941263.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049947040.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049939463.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery"
XP_049941196.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049951244.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049960226.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_049960705.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049948578.1	5	KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-7817;Reactome: R-HSA-1483148;MetaCyc: PWY-5668	"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"Cardiolipin biosynthesis I"
XP_049947502.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049958886.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049959947.1	8	MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Propanoate metabolism"
XP_049939282.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780	"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome"
XP_049943252.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049958865.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049940466.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049954471.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection"
XP_049960180.1	20	MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337	"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_049941957.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_049949394.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049963712.1	11	KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539	"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Ammonia assimilation cycle II";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism"
XP_049961198.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_049952775.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_049957884.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049955938.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049953508.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_049956876.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049964726.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049953720.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049943961.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1"
XP_049961392.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049950703.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_049943216.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049942154.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049946122.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049950343.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049950104.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049945597.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924;Reactome: R-HSA-210744;Reactome: R-HSA-73762	"Notch-HLH transcription pathway";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation"
XP_049956266.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049941152.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049962429.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes"
XP_049950070.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049961303.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049959740.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049950402.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049963939.1	11	KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9	"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism";"Riboflavin metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049949810.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049951686.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049953103.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049953442.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-186763	"MET receptor recycling";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"Downstream signal transduction"
XP_049947786.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049964797.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049949257.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049937817.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049938426.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049954731.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049962809.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049956107.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_049941199.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I"
XP_049951375.1	5	MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;Reactome: R-HSA-6798695	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I";"Neutrophil degranulation"
XP_049937877.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049949745.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049951729.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049964086.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049960855.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049961521.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049963544.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_049947293.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049953762.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049959316.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049964142.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049949332.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-168325	"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis"
XP_049952548.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049964250.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049939278.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;MetaCyc: PWY-7919	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)"
XP_049944174.1	29	Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-3371511	"Translesion synthesis by POLI";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HSF1 activation"
XP_049953866.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049955588.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049938047.1	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049942189.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049949573.1	5	Reactome: R-HSA-194840;Reactome: R-HSA-446388;Reactome: R-HSA-416482;Reactome: R-HSA-8964616;Reactome: R-HSA-193648	"Rho GTPase cycle";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G alpha (12/13) signalling events";"G beta:gamma signalling through CDC42";"NRAGE signals death through JNK"
XP_049960909.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_049938901.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049937525.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049956477.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_049950912.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049964792.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049956251.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_049939638.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049947756.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049937719.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049959319.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049960089.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-532668	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049952167.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049947365.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049963038.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049958868.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049951053.1	4	Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Spermidine biosynthesis III"
XP_049954238.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049963557.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936964	"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049952767.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049953400.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049961384.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049950914.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049960740.1	5	Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;MetaCyc: PWY-7511	"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Protein ubiquitination"
XP_049956673.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049937377.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049963047.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_049953960.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049960257.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049942489.1	7	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16	"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_049953672.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
XP_049947310.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049961551.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152	"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_049950060.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_049946648.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049942079.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_049940856.1	6	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_049964664.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049941321.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049954209.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049952153.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049964675.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-532668	"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049947569.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049938888.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049955149.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_049948278.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049939694.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_049940531.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_049964719.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049960719.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049942316.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_049958920.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049963275.1	12	KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5873	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_049938399.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049958046.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049950105.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049962889.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049953196.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049950834.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049950563.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049950106.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049962520.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-882	"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_049963742.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_049963564.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049960759.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049962944.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation"
XP_049949979.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_049942109.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_049946485.1	7	KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352	"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis"
XP_049958479.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049964092.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049961678.1	9	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation"
XP_049953314.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids"
XP_049949747.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049955104.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049958906.1	6	MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_049963786.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049953686.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049950413.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049943629.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049942145.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049962759.1	13	KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"EPHA-mediated growth cone collapse";"Thermogenesis";"EPHB-mediated forward signaling";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection"
XP_049963909.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049937519.1	5	KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Sphingolipid metabolism"
XP_049957959.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049960917.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049957591.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049941468.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049953437.1	8	MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5738	"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis"
XP_049949329.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227	"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA"
XP_049955990.1	5	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism"
XP_049941762.1	10	KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901	"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_049962934.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-6859	"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis"
XP_049950299.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049940549.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049964722.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049962266.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_049945679.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049941590.1	12	KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13	"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism"
XP_049960291.1	6	KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004	"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I"
XP_049938137.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049964550.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049963123.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049945681.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049949100.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049963168.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870	"Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins"
XP_049955211.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200	"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049947839.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049958616.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049938793.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049937995.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049961684.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis"
XP_049953844.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049964415.1	13	MetaCyc: PWY-6842;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-2261;MetaCyc: PWY-7112	"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification"
XP_049954261.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_049944154.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049947126.1	18	Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6	"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_049963230.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049960352.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049943948.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049940930.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049938099.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_049959020.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049962279.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049940448.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049941133.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049956721.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049957313.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049939256.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049942351.1	12	MetaCyc: PWY-6932;MetaCyc: PWY-6683;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25	"Selenate reduction";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Sulfite oxidation III";"Selenocompound metabolism";"Monobactam biosynthesis";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism"
XP_049940143.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049937872.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049949272.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049949712.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049961299.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049955635.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049954163.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049949921.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049953322.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_049955420.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049955564.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049954216.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_049941825.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_049962862.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_049954251.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51	"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism"
XP_049955499.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049949584.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049940016.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049949247.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049946008.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049943402.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049942480.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049952667.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049953316.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049947767.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049962183.1	15	Reactome: R-HSA-8863795;Reactome: R-HSA-9652282;Reactome: R-HSA-9665246;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665249;Reactome: R-HSA-9665233;Reactome: R-HSA-9665251	"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to lapatinib"
XP_049938383.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049942927.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049962800.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049954591.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049939776.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049947313.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049959225.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;Reactome: R-HSA-379716;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049962618.1	10	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-7328	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_049960459.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049944801.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049956003.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049949426.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_049950868.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_049939954.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941985.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049937364.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049939519.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_049944685.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049938349.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_049939900.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049963894.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049959926.1	4	Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260	"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049941172.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049960288.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049958127.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049960985.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049957373.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049960444.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_049964662.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049964780.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049937563.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049960638.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3	"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049960011.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049961395.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_049954237.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049952765.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049963751.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_049938530.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049956002.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049946231.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-72731;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049940636.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049956806.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049948101.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049940125.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049939493.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049941395.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis"
XP_049945572.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049960322.1	4	KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931	"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_049951374.1	5	MetaCyc: PWY-7210;Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism"
XP_049964087.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049960927.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049949637.1	18	MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7226	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_049953557.1	19	MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;Reactome: R-HSA-163765;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5	"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_049946184.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049952884.1	11	Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_049945939.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049963222.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049953514.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049938078.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-176409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_049964696.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049963974.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049958907.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022692	"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity"
XP_049942901.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049943996.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236	"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049956246.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049960181.1	20	MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337	"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_049954659.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049941514.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960721.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049952107.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049960859.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049949205.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049951958.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049942945.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049960158.1	6	KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane"
XP_049942296.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049952822.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049942575.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Protein ubiquitination"
XP_049940493.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049950005.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7177;MetaCyc: PWY-7185;Reactome: R-HSA-499943	"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates"
XP_049959935.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049951573.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049945674.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049964538.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049956403.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049937916.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900	"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4"
XP_049950329.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis"
XP_049958610.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9609690	"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Early Events"
XP_049937819.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049950108.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049955391.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699	"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels"
XP_049937472.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049939365.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049950964.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049951898.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049946243.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049957969.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049950994.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049940174.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049941783.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_049950318.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049949323.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049956709.1	8	KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"T cell receptor signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049958367.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049957337.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049955740.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736	"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors"
XP_049950826.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049942104.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049961537.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049962885.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049948830.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049956329.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049937617.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049942891.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049956962.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049939240.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049948856.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III"
XP_049953157.1	8	Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6783310;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Fanconi Anemia Pathway";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_049951277.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049956120.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049952658.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049960971.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049963082.1	7	MetaCyc: PWY-6610;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217	"Adenine salvage";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Purine metabolism";"Purine salvage"
XP_049961833.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049938784.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_049963758.1	32	Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-113418	"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex"
XP_049958600.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049939960.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049960008.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_049949760.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049963570.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952874.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_049958456.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962378.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049941692.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049941114.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-71737	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis"
XP_049951273.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049958336.1	13	Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52	"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation"
XP_049939646.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-241;Reactome: R-HSA-1475029	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide"
XP_049943151.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049958503.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049952004.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049958904.1	6	MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6364	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_049946043.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049957575.1	10	KEGG: 00670+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7187;Reactome: R-HSA-69205;MetaCyc: PWY-7210;MetaCyc: PWY-7199;MetaCyc: PWY-3841;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943	"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049963155.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049962373.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049956816.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049952750.1	6	MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_049946618.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049941704.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_049939510.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Kinesins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation"
XP_049953215.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049938244.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049946921.1	10	KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Galactose metabolism";"HS-GAG degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049964466.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049954060.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_049950373.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_049961734.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049962321.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440	"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network"
XP_049939639.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049962198.1	15	Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282	"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling"
XP_049949320.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049955969.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_049951953.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049951508.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049938510.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase"
XP_049957168.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049949746.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049961363.1	3	KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685	"Purine metabolism";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species"
XP_049962286.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049963252.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049941789.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-5696395;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214	"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_049956676.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049937823.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049938665.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049951376.1	5	MetaCyc: PWY-7210;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism"
XP_049958016.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_049952312.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049957482.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049956921.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049947594.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049960114.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049954815.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049949433.1	4	KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049940564.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049958326.1	18	Reactome: R-HSA-8953750;MetaCyc: PWY-7511;Reactome: R-HSA-5689901;Reactome: R-HSA-5693579;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554	"Transcriptional Regulation by E2F6";"Protein ubiquitination";"Metalloprotease DUBs";"Homologous DNA Pairing and Strand Exchange";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049942245.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049949508.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049946047.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_049964747.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_049946587.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049943489.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049942922.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049946001.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_049955921.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049956556.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-983168	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049950409.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049948996.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253	"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_049946589.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049954541.1	10	Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"RSK activation";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_049950936.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049941737.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049961148.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049962221.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049954322.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049959325.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049956939.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049949153.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_049942537.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049942502.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049962644.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049953474.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049954793.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049951357.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049950685.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049957388.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049955799.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049960022.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049959800.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049941538.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_049959864.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049958403.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049953856.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049963266.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049959605.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049958096.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049952941.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049956359.1	6	KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_049942206.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049937698.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049943177.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-110362	"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair"
XP_049961593.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049950877.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049958672.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049944237.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC"
XP_049962819.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049946045.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049958028.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049943016.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049946321.1	7	Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Translation initiation complex formation"
XP_049939503.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049952192.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049940446.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049939401.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049953808.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049937279.1	9	Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18	"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes"
XP_049960363.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049951380.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_049940861.1	15	MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;Reactome: R-HSA-70171	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycolysis"
XP_049940547.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049946137.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049952921.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_049942448.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049955370.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952672.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049938773.1	7	MetaCyc: PWY-7854;MetaCyc: PWY-6969;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-7295	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-arabinose degradation IV"
XP_049938716.1	11	MetaCyc: PWY-6352;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-168138;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_049939373.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049964515.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_049962803.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049956020.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_049940147.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049952065.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049950023.1	9	Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_049963805.1	24	Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148	"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Kinesins";"MHC class II antigen presentation";"Cilium Assembly";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049949597.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049949852.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_049962368.1	8	MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049941139.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049938815.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049943567.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049950071.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049959577.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049942525.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049939844.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_049937488.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049938241.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_049940306.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_049943164.1	21	Reactome: R-HSA-937041;Reactome: R-HSA-933542;Reactome: R-HSA-1169091;Reactome: R-HSA-168638;Reactome: R-HSA-5684264;Reactome: R-HSA-937039;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-5603027;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-933543;Reactome: R-HSA-168927;Reactome: R-HSA-5603029;Reactome: R-HSA-1810476;Reactome: R-HSA-975144;Reactome: R-HSA-5602636;Reactome: R-HSA-2871837;Reactome: R-HSA-5357905;Reactome: R-HSA-445989;Reactome: R-HSA-9020702	"IKK complex recruitment mediated by RIP1";"TRAF6 mediated NF-kB activation";"Activation of NF-kappaB in B cells";"NOD1/2 Signaling Pathway";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IRAK1 recruits IKK complex";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TICAM1, RIP1-mediated IKK complex recruitment";"IkBA variant leads to EDA-ID";"RIP-mediated NFkB activation via ZBP1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IKBKB deficiency causes SCID";"FCERI mediated NF-kB activation";"Regulation of TNFR1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling"
XP_049956606.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049963846.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049944979.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049958050.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049958638.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049949363.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049951021.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049963250.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049956303.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049942848.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049961514.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049963458.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049963787.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951127.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049948876.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049945646.1	19	Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-389359;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-114604;Reactome: R-HSA-418885	"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"Rho GTPase cycle";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"CD28 dependent Vav1 pathway";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"GPVI-mediated activation cascade";"DCC mediated attractive signaling"
XP_049940013.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049941437.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049940108.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049952241.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049939547.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049954539.1	10	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"RSK activation";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection"
XP_049950875.1	4	MetaCyc: PWY-5030;MetaCyc: PWY-5028;KEGG: 00340+3.5.2.7;Reactome: R-HSA-70921	"L-histidine degradation III";"L-histidine degradation II";"Histidine metabolism";"Histidine catabolism"
XP_049960225.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049953095.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
XP_049941479.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049962701.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049963667.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049958765.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_049953283.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_049958862.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049956970.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_049945855.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049959685.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049941541.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049952106.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049961794.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049963120.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049949330.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227	"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA"
XP_049959362.1	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_049950363.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049948074.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_049960264.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049939746.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_049959278.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049962798.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049937975.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049952020.1	6	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049964617.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049939991.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049947263.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049960646.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049946797.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837	"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation"
XP_049957281.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049962405.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_049947024.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049956855.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049964493.1	14	Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167242	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049956791.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049949201.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_049959950.1	8	Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27	"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism"
XP_049949277.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-917937;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport";"Neddylation"
XP_049958895.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049942110.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049937474.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
XP_049964158.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049954744.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049947235.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5856	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_049960361.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049939950.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_049954549.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-400206	"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha"
XP_049947051.1	7	Reactome: R-HSA-4549356;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;MetaCyc: PWY-5265	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)"
XP_049960125.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049963619.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049940720.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049938147.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049964448.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049950952.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5674400	"Macroautophagy";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049941791.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049964665.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049938327.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049937855.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049963224.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049958926.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960928.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049962211.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_049956877.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_049958393.1	10	KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166	"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_049962202.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049955800.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049950134.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049953522.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049961998.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049954754.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell"
XP_049942038.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049950562.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049937603.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049952017.1	7	KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism"
XP_049960999.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049961066.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049946002.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_049950980.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049961348.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_049940397.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049942299.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049937455.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049942585.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049942382.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049944028.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-5696397	"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049943457.1	9	KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049955980.1	5	MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_049946182.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049959376.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709	"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins"
XP_049949761.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_049948523.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049950482.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944	"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2"
XP_049944116.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049962585.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049959349.1	31	MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-5142;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-7388;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-6282;Reactome: R-HSA-75105	"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Biotin metabolism";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis"
XP_049954231.1	7	MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_049956316.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049953197.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049949920.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049943277.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049940060.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049949685.1	24	Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Kinesins";"Cilium Assembly";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049958591.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_049957634.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049961220.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049962277.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049960378.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049948103.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049950995.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy"
XP_049943889.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049943733.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_049942920.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049956805.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049959854.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis"
XP_049949490.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049950667.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_049949421.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049939904.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049953890.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049959048.1	16	MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-2221;Reactome: R-HSA-70263;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484	"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)"
XP_049939643.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_049940412.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049943194.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049962300.1	9	MetaCyc: PWY-5265;MetaCyc: PWY-6385;Reactome: R-HSA-446193;KEGG: 00550+2.4.1.227;KEGG: 00510+2.4.1.141;Reactome: R-HSA-5633231;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6470;MetaCyc: PWY-6471	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_049960637.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049953519.1	6	MetaCyc: PWY-622;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049941687.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_049960872.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049958522.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955636.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049947332.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049960117.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049949582.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049954161.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049937600.1	5	MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_049952881.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049942236.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049938881.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049960796.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049961432.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950265.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049946434.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049958450.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049941134.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049951867.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049954071.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049961455.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540	"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1"
XP_049962118.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049954750.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049960668.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049949284.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049941145.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049957900.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_049949372.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049940616.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049960416.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049964782.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049939551.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049945994.1	7	Reactome: R-HSA-1268020;Reactome: R-HSA-163210;MetaCyc: PWY-7980;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2	"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis"
XP_049951372.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination"
XP_049959430.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049952530.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049956384.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049952482.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049958301.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049949434.1	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_049957556.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_049948670.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_049963953.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049942220.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049962997.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049954087.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7338	"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_049962950.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049963111.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"G1/S-Specific Transcription";"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049959752.1	11	Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5696400	"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER"
XP_049955837.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110328	"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049937398.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_049964031.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049958082.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049960573.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_049954682.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049951196.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049961153.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049962291.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049951289.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_049964895.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049954792.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049964203.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941354.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049958457.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954988.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049960636.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049955834.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049948021.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049956233.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049959075.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049949098.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049952500.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_049951875.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_049950378.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049956686.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049938874.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049960820.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227	"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA"
XP_049962394.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795	"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling"
XP_049939962.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049942000.1	10	MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_049959402.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_049959019.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Neutrophil degranulation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049943027.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941457.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_049943028.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959898.1	8	Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049948012.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis"
XP_049963776.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049941919.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049961806.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049942207.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049939392.1	14	MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_049955362.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049939701.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049962609.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049961302.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049952263.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049955984.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049964814.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049956057.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049959850.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049956959.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049956799.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049943916.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049949471.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_049941749.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049952089.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049950965.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049960974.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049959532.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049943154.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049962432.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049941802.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049947734.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_049956839.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813	"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids"
XP_049943422.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049953635.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_049961104.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049937944.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_049953924.1	4	MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20	"Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism"
XP_049956379.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049939939.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049937790.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049950601.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049948507.1	2	KEGG: 00710+2.7.1.19;MetaCyc: PWY-5723	"Carbon fixation in photosynthetic organisms";"Rubisco shunt"
XP_049946060.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049951762.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049954551.1	11	Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114	"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Estrogen-dependent gene expression";"PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_049938429.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952718.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049940935.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049949282.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_049942737.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049951188.1	22	MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-6598;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7053;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049940684.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049943030.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049943138.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049940790.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049951034.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049942349.1	12	KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6683;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4	"Sulfur metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism";"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfite oxidation III";"Selenocompound metabolism"
XP_049951646.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049960881.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049955250.1	5	Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049949571.1	5	Reactome: R-HSA-446388;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049947939.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049943080.1	12	MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;MetaCyc: PWY-7343	"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I"
XP_049941393.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049949757.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049958946.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049954897.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049943147.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049961820.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_049952425.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049944687.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-975957	"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049944679.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-450408	"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049960474.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049950506.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_049958288.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049964762.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049949557.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049940971.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049940436.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731	"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_049953641.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049943436.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5656121	"HSF1 activation";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Translesion synthesis by POLI"
XP_049963703.1	11	MetaCyc: PWY-6964;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675	"Ammonia assimilation cycle II";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)"
XP_049954614.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049941031.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Neutrophil degranulation";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049941555.1	14	Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix"
XP_049942288.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Macroautophagy";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Intraflagellar transport";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation"
XP_049950830.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049956727.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049942179.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_049955260.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_049952215.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049962444.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049956248.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049954141.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049939179.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_049952959.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049954308.1	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_049962184.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049964883.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049938711.1	22	MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134	"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation"
XP_049961515.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049949524.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049956716.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049953490.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049939804.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049960976.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049963134.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_049951721.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049964024.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049957342.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049955831.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049941634.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049940068.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049950043.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses"
XP_049958560.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049962514.1	11	MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3881	"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis"
XP_049954885.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049963217.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049959448.1	14	Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-6453	"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Ether lipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Sphingolipid metabolism";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis"
XP_049957712.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049961177.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049959372.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346	"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis"
XP_049938108.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783	"Ether lipid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation"
XP_049938625.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049960932.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049960787.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049959803.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049952315.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952561.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049941219.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049959869.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049953121.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5578749	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs"
XP_049956417.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049955764.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049943433.1	29	Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Meiotic recombination";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049954958.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049954349.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049953532.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049940580.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049937428.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049949748.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408	"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism"
XP_049950840.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049946580.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049947800.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049942487.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049948624.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049940853.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049943434.1	29	Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453	"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Meiotic recombination";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response"
XP_049945676.1	10	Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_049950710.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049950854.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_049950528.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049958719.1	2	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_049960984.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049953624.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049942178.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_049961539.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941542.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049957148.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049952671.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049953102.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049964881.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049958696.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049962071.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_049960254.1	13	Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900	"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4"
XP_049947336.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049958392.1	10	MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II"
XP_049963881.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049942337.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_049937452.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049964019.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955550.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_049948875.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961897.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_049954387.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049963794.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049941747.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049956096.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049963822.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049957480.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049953521.1	2	KEGG: 00450+1.8.1.9;Reactome: R-HSA-499943	"Selenocompound metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049956046.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
YP_010417141.1	7	MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;MetaCyc: PWY-3781;MetaCyc: PWY-6692	"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation"
XP_049941671.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049950828.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049964604.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049939731.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749	"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs"
XP_049953996.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049958005.1	4	MetaCyc: PWY-2781;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75	"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis"
XP_049954065.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049937358.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049961059.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049960175.1	20	MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920	"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)"
XP_049958422.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_049951785.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5	"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_049947418.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049958944.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling"
XP_049958599.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049940683.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049955850.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049959408.1	17	Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-69166	"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate"
XP_049951826.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049943249.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049964186.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049949583.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049961035.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_049953265.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049946123.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049960967.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049955620.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049938400.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049962717.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049943017.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049953473.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_049955010.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604	"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling"
XP_049940966.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049950640.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049954271.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049953052.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_049942478.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049959903.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049953952.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049961835.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049949953.1	7	MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-5659;Reactome: R-HSA-446205	"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose"
XP_049941056.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049948586.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_049961587.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049952267.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049961076.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049964357.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049958984.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049941711.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049939350.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049960251.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049939927.1	14	MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-4302;Reactome: R-HSA-71403	"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Methylaspartate cycle";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)"
XP_049945862.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049953502.1	33	Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159230	"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA"
XP_049939688.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_049937457.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049963320.1	7	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-176187	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress"
XP_049950310.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049960450.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049955628.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049943390.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049941722.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049941441.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049952772.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049956392.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049963427.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941053.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049948099.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049950049.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049938605.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049940511.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049954656.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049950042.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines"
XP_049939467.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049941695.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049955985.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049951216.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049946362.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_049953506.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764	"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling"
XP_049959414.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_049958327.1	18	Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5689901;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;MetaCyc: PWY-7511;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632	"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Metalloprotease DUBs";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"Protein ubiquitination";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis"
XP_049961236.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049939219.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049951262.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049944150.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049959068.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049943032.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049957017.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049943179.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-73930	"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_049941267.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049942285.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049955870.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049964637.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8939236;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production"
XP_049953512.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049941560.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049963325.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049949927.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049948855.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_049943019.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049939696.1	182	Reactome: R-HSA-8876493;Reactome: R-HSA-936440;Reactome: R-HSA-2467813;Reactome: R-HSA-72702;Reactome: R-HSA-209543;Reactome: R-HSA-937041;Reactome: R-HSA-9013507;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975163;Reactome: R-HSA-72689;Reactome: R-HSA-5654726;Reactome: R-HSA-110312;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-5675482;Reactome: R-HSA-9613829;Reactome: R-HSA-201681;Reactome: R-HSA-975144;Reactome: R-HSA-912631;Reactome: R-HSA-9033241;Reactome: R-HSA-174178;Reactome: R-HSA-1169408;Reactome: R-HSA-8951664;Reactome: R-HSA-2408557;Reactome: R-HSA-8856825;Reactome: R-HSA-983168;Reactome: R-HSA-5357905;Reactome: R-HSA-8866652;Reactome: R-HSA-8849469;Reactome: R-HSA-205043;Reactome: R-HSA-9020702;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5696395;Reactome: R-HSA-2173795;Reactome: R-HSA-8856828;Reactome: R-HSA-2559582;Reactome: R-HSA-72764;Reactome: R-HSA-68949;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-2672351;Reactome: R-HSA-8863795;Reactome: R-HSA-182971;Reactome: R-HSA-192823;Reactome: R-HSA-3785653;Reactome: R-HSA-936964;Reactome: R-HSA-2559580;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-179409;Reactome: R-HSA-5684264;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-2173791;Reactome: R-HSA-901032;Reactome: R-HSA-5689896;Reactome: R-HSA-1358803;Reactome: R-HSA-2979096;Reactome: R-HSA-532668;Reactome: R-HSA-5689603;Reactome: R-HSA-6807004;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-174490;Reactome: R-HSA-1253288;Reactome: R-HSA-69601;Reactome: R-HSA-9013973;Reactome: R-HSA-6783310;Reactome: R-HSA-156902;Reactome: R-HSA-5689901;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-72706;Reactome: R-HSA-937039;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-1295596;Reactome: R-HSA-211733;Reactome: R-HSA-937072;Reactome: R-HSA-6791226;Reactome: R-HSA-5693565;Reactome: R-HSA-8875360;Reactome: R-HSA-156827;Reactome: R-HSA-2122947;Reactome: R-HSA-2691232;Reactome: R-HSA-9014325;Reactome: R-HSA-110320;Reactome: R-HSA-975957;Reactome: R-HSA-6782210;Reactome: R-HSA-8852276;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-4641263;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5654727;Reactome: R-HSA-174154;Reactome: R-HSA-400253;Reactome: R-HSA-6804756;Reactome: R-HSA-168927;Reactome: R-HSA-8939902;Reactome: R-HSA-917729;Reactome: R-HSA-450408;Reactome: R-HSA-9636383;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5675221;Reactome: R-HSA-69541;Reactome: R-HSA-445989;Reactome: R-HSA-2565942;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-8941858;Reactome: R-HSA-9633012;Reactome: R-HSA-5658442;Reactome: R-HSA-5696397;Reactome: R-HSA-9615710;Reactome: R-HSA-4641257;Reactome: R-HSA-5654732;Reactome: R-HSA-5357956;Reactome: R-HSA-5205685;Reactome: R-HSA-168928;Reactome: R-HSA-1799339;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-3134975;Reactome: R-HSA-8948747;Reactome: R-HSA-5696394;Reactome: R-HSA-975110;Reactome: R-HSA-2173796;Reactome: R-HSA-6804760;Reactome: R-HSA-5689880;Reactome: R-HSA-3322077;Reactome: R-HSA-3769402;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-450321;Reactome: R-HSA-9637628;Reactome: R-HSA-9646399;Reactome: R-HSA-168638;Reactome: R-HSA-209560;Reactome: R-HSA-977225;Reactome: R-HSA-162588;Reactome: R-HSA-5656121;Reactome: R-HSA-917937;Reactome: R-HSA-2559585;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8866654;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-937042;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-2173788;Reactome: R-HSA-5655862;Reactome: R-HSA-6781827;Reactome: R-HSA-180585;Reactome: R-HSA-2894862;Reactome: R-HSA-6804757;Reactome: R-HSA-1236382;Reactome: R-HSA-1236974;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-174048;Reactome: R-HSA-75815;Reactome: R-HSA-175474;Reactome: R-HSA-6781823	"InlA-mediated entry of Listeria monocytogenes into host cells";"Negative regulators of DDX58/IFIH1 signaling";"Separation of Sister Chromatids";"Ribosomal scanning and start codon recognition";"p75NTR recruits signalling complexes";"IKK complex recruitment mediated by RIP1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Formation of a pool of free 40S subunits";"Negative regulation of FGFR1 signaling";"Translesion synthesis by REV1";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Regulation of necroptotic cell death";"Chaperone Mediated Autophagy";"TCF dependent signaling in response to WNT";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of signaling by CBL";"Peroxisomal protein import";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ISG15 antiviral mechanism";"Neddylation";"Selenocysteine synthesis";"Cargo recognition for clathrin-mediated endocytosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of TNFR1 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Clathrin-mediated endocytosis";"Senescence-Associated Secretory Phenotype (SASP)";"Eukaryotic Translation Termination";"Orc1 removal from chromatin";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Stimuli-sensing channels";"Downregulation of ERBB2 signaling";"EGFR downregulation";"Viral mRNA Translation";"Myoclonic epilepsy of Lafora";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Oxidative Stress Induced Senescence";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"APC-Cdc20 mediated degradation of Nek2A";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"ER Quality Control Compartment (ERQC)";"Ovarian tumor domain proteases";"Downregulation of ERBB2:ERBB3 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"UCH proteinases";"Negative regulation of MET activity";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Membrane binding and targetting of GAG proteins";"Downregulation of ERBB4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TICAM1-dependent activation of IRF3/IRF7";"Fanconi Anemia Pathway";"Peptide chain elongation";"Metalloprotease DUBs";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"IRAK1 recruits IKK complex";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Spry regulation of FGF signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"InlB-mediated entry of Listeria monocytogenes into host cell";"L13a-mediated translational silencing of Ceruloplasmin expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Translesion Synthesis by POLH";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of FZD by ubiquitination";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of FGFR2 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Circadian Clock";"Regulation of TP53 Activity through Phosphorylation";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of RUNX2 expression and activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Prevention of phagosomal-lysosomal fusion";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of MAPK pathway";"Stabilization of p53";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of RUNX3 expression and activity";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of RAS by GAPs";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Late endosomal microautophagy";"Degradation of AXIN";"Negative regulation of FGFR3 signaling";"TNFR1-induced NFkappaB signaling pathway";"Pink/Parkin Mediated Mitophagy";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"SRP-dependent cotranslational protein targeting to membrane";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"Regulation of innate immune responses to cytosolic DNA";"Regulation of PTEN localization";"DNA Damage Recognition in GG-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of TP53 Activity through Methylation";"Ub-specific processing proteases";"Glycogen synthesis";"Deactivation of the beta-catenin transactivating complex";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Modulation by Mtb of host immune system";"Aggrephagy";"NOD1/2 Signaling Pathway";"NF-kB is activated and signals survival";"Amyloid fiber formation";"Budding and maturation of HIV virion";"Translesion synthesis by POLI";"Iron uptake and transport";"Oncogene Induced Senescence";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"E3 ubiquitin ligases ubiquitinate target proteins";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Downregulation of TGF-beta receptor signaling";"Translesion synthesis by POLK";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Vif-mediated degradation of APOBEC3G";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of TP53 Degradation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"ER-Phagosome pathway";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Ubiquitin-dependent degradation of Cyclin D";"Assembly Of The HIV Virion";"Formation of TC-NER Pre-Incision Complex"
XP_049952493.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_049952008.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049964863.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049950963.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049956558.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017	"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6"
XP_049959879.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049940163.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049957906.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049960578.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049942892.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049960173.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049960394.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049952581.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049941703.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049964907.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049957565.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049961495.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049951687.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049949109.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049955541.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049938427.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049942596.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695	"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation"
XP_049963052.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_049950919.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049937357.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049947091.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049949581.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049951042.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049941269.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_049950107.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049960913.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049955255.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_049959865.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049951310.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049951878.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049941976.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049963573.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953807.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049957040.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_049963828.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049941920.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049952275.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_049958213.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049943890.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049951068.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049950771.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_049944243.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049942704.1	16	Reactome: R-HSA-3134963;Reactome: R-HSA-5602680;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-6811558;Reactome: R-HSA-975871;Reactome: R-HSA-1236974;Reactome: R-HSA-5603037;Reactome: R-HSA-166058;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-975155;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-209543;Reactome: R-HSA-975138	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 deficiency (TLR5)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 cascade initiated on plasma membrane";"ER-Phagosome pathway";"IRAK4 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"MyD88 dependent cascade initiated on endosome";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_049961317.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049950414.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049937815.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049954546.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168	"RORA activates gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_049953738.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049959444.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_049962544.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049939250.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049960883.1	26	Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation"
XP_049962828.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049944248.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049951373.1	5	MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210	"UTP and CTP dephosphorylation I";"Purine metabolism";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049960826.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_049956119.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049945972.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049953898.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049964071.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049949418.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049955881.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049950469.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049946600.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049958377.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049955092.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049963935.1	8	Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049945680.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049963648.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-427413	"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression"
XP_049942468.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049943153.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049943673.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049955705.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_049943035.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940471.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049949629.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049941144.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049964176.1	8	Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_049955114.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049963910.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049963219.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049943146.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049937556.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049957627.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049956350.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049951307.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049953733.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049950829.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049956301.1	11	Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69017;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-1362277;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Transcription of E2F targets under negative control by DREAM complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_049953907.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_049950705.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_049944153.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049945183.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049944763.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198	"Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis"
XP_049943251.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049958391.1	10	MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055	"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_049937280.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_049956868.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4615885	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins"
XP_049942113.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049943713.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902	"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity"
XP_049958835.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_049956771.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049961346.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049952850.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049954247.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049946320.1	7	Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72662	"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_049939928.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954235.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049957892.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049959742.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049950967.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049944886.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049951040.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_049951690.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049954883.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049947193.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049961138.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049960952.1	7	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism"
XP_049960129.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049956834.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049952074.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049949370.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049961224.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049943105.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049953133.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049953438.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_049943155.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_049954309.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049952580.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049941277.1	7	MetaCyc: PWY-31;MetaCyc: PWY-6922;Reactome: R-HSA-70635;MetaCyc: PWY-46;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1	"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Arginine biosynthesis";"Urea cycle";"Arginine and proline metabolism"
XP_049948252.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049955662.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049956025.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049961201.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression"
XP_049947831.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049949496.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049959812.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049955129.1	15	Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246	"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib"
XP_049938622.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049944065.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049957165.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049950774.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_049950480.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049945401.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049938466.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049943862.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049961212.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049956062.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_049945941.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049946588.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049957404.1	11	Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-1268020;Reactome: R-HSA-111459	"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage"
XP_049954837.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049953688.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049939004.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049956850.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049963076.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049961898.1	15	MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-6142	"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway I";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049938341.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049959260.1	2	Reactome: R-HSA-192456;Reactome: R-HSA-975634	"Digestion of dietary lipid";"Retinoid metabolism and transport"
XP_049951877.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_049959304.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950047.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines"
XP_049958805.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049960640.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118	"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle"
XP_049948134.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049940849.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049937693.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049949634.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049949971.1	5	Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9630222	"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding"
XP_049954329.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049958131.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_049941334.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049956207.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049950539.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049937538.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049955085.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049949191.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_049956641.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_049955983.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049959741.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049947652.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049962311.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962996.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_049950666.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049952985.1	18	KEGG: 00280+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00620+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-71403;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-70268;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-5362517;KEGG: 00640+1.8.1.4;Reactome: R-HSA-6783984	"Valine, leucine and isoleucine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Pyruvate metabolism";"Glycine, serine and threonine metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Lysine catabolism";"Signaling by Retinoic Acid";"Propanoate metabolism";"Glycine degradation"
XP_049962716.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049957444.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049939249.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049942308.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049957895.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049940929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049952314.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937654.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049938990.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049963248.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049939751.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440	"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_049954654.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049958909.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049956048.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049944355.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049955373.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049946461.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049943688.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049948599.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049941032.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049956069.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_049958455.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049959867.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049940538.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049953523.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049962777.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829	"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049945450.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049950779.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049962002.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049953297.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049962543.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_049964542.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049946645.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049942885.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049946601.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049954879.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049959531.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049955697.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049960161.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049942734.1	18	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4	"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism"
XP_049952064.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049953261.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049939192.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049958094.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_049955766.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_049941433.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049945673.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_049941154.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-8060;Reactome: R-HSA-71336;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4	"Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway"
XP_049964903.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_049942450.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049951486.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049961204.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-75893;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826	"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Growth hormone receptor signaling";"Collagen degradation";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049941125.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-1445148	"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Cilium Assembly";"Kinesins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049948406.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049947913.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049959013.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049941427.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049948251.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049941901.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049947441.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049950431.1	26	Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049939742.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_049949337.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049953443.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_049941480.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049958380.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049961054.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049955232.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049944980.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049945448.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049952122.1	6	MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17	"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation"
XP_049942272.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049951989.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049953584.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049949406.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049953287.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049963957.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049963228.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049953685.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049963284.1	21	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7219;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Thiamine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_049954537.1	7	MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204	"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_049953134.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049941382.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049963980.1	13	MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-6545;Reactome: R-HSA-74259;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism"
XP_049945961.1	7	Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862	"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049949650.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049937269.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049940126.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049950296.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049954735.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_049954058.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049957197.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049961355.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049939956.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049946484.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049959449.1	14	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-6453	"Ether lipid metabolism";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis"
XP_049960393.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049955618.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049951509.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049952702.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049949328.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333	"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049959849.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes"
XP_049963121.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049952422.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049937801.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049960127.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049954215.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_049940548.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049961051.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049947998.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049963943.1	11	KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206	"Starch and sucrose metabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_049951846.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049953493.1	12	KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-6672;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes"
XP_049944803.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049956720.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049962227.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049962191.1	15	Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246	"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib"
XP_049938229.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049937914.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_049937633.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation"
XP_049960263.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049941252.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049963229.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049964820.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049964777.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049942233.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049942283.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_049946977.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049958557.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-210746	"Regulation of gene expression in beta cells";"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"
XP_049960513.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049953300.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049947333.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049947303.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_049956598.1	19	Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-8876725;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-3214858	"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Protein methylation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"RMTs methylate histone arginines"
XP_049958371.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049954344.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049961304.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049959503.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_049952351.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049946451.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049938401.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049938677.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049959411.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049953948.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling"
XP_049960435.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-203754	"Protein ubiquitination";"NOSIP mediated eNOS trafficking"
XP_049949517.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049952595.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049947879.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049952982.1	7	KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36	"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_049959729.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049954014.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation"
XP_049962807.1	5	Reactome: R-HSA-209543;Reactome: R-HSA-205043;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-209560	"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival"
XP_049963982.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049953388.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049960794.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049943186.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049954510.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_049961227.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049937722.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049950399.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049939499.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_049962424.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049954320.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049950263.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049958494.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049961137.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049963276.1	12	KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5857	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_049953004.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049942907.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049951019.1	9	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049961071.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049952715.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049957311.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_049956718.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049955477.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049957434.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049938208.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049954506.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-6803207	"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049938516.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049943033.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961219.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049952021.1	6	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049962443.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049949335.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049962721.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049951738.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049962497.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_049956961.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_049938348.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049955982.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049961232.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049950358.1	33	Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase"
XP_049963646.1	5	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413	"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression"
XP_049961872.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049946462.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049959868.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049940705.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049952845.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049937616.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049958375.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049949024.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049940633.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049964896.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049963985.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049951890.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558	"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RAF activation";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_049960162.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049937344.1	13	MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7112;MetaCyc: PWY-7533;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1	"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism"
XP_049951240.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049950658.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049961207.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049949653.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049948682.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Retinoid metabolism and transport";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049943548.1	27	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-5358749;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5250924;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-5610785;Reactome: R-HSA-198323;Reactome: R-HSA-196299;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-399956	"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"S37 mutants of beta-catenin aren't phosphorylated";"Thermogenesis";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"B-WICH complex positively regulates rRNA expression";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Human papillomavirus infection";"Truncations of AMER1 destabilize the destruction complex";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"GLI3 is processed to GLI3R by the proteasome";"AKT phosphorylates targets in the cytosol";"Beta-catenin phosphorylation cascade";"Human immunodeficiency virus 1 infection";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"CRMPs in Sema3A signaling"
XP_049958615.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049943458.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_049952212.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049961173.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation"
XP_049938712.1	22	MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-6598;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-7592;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6958;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049944226.1	9	Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-196780	"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism"
XP_049954585.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049940066.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049955256.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049940637.1	4	KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I"
XP_049943493.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049940001.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950045.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695	"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation"
XP_049949523.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049959754.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis"
XP_049964724.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049937553.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_049953193.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5744	"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation"
XP_049956696.1	18	MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms"
XP_049956038.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049944066.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_049954910.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_049950377.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049958399.1	14	Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167287	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery"
XP_049960479.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049940309.1	4	Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_049962093.1	7	Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8943724	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"HCMV Early Events";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription"
XP_049958395.1	10	MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055	"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis"
XP_049950357.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214	"snRNP Assembly";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins"
XP_049943945.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049959450.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049952501.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049958588.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049958035.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049959559.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_049939548.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049962738.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_049937485.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049940729.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049959930.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049959506.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_049941048.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049940567.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049941730.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049943546.1	9	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049961871.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049941516.1	30	Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-2644607;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-1170546;Reactome: R-HSA-195253;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-2122947;Reactome: R-HSA-174113;Reactome: R-HSA-9020702	"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Prolactin receptor signaling";"Degradation of beta-catenin by the destruction complex";"Iron uptake and transport";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling"
XP_049957292.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049959318.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049957430.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049959122.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049957181.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049952342.1	7	KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906;Reactome: R-HSA-71336;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Pentose phosphate pathway";"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049956818.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049939726.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049955159.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937915.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-196025	"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions"
XP_049964306.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953874.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"Neutrophil degranulation";"RAF/MAP kinase cascade";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049958438.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049959600.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049957946.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946	"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin"
XP_049964023.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253	"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex"
XP_049953281.1	4	KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;KEGG: 00010+3.1.3.9;Reactome: R-HSA-70263	"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_049949558.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049938936.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049962724.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049939195.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_049946070.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049944833.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049938053.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049954737.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049954400.1	57	Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534	"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4"
XP_049952090.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049941995.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_049963585.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049938717.1	11	KEGG: 00562+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;Reactome: R-HSA-168138;KEGG: 04070+2.7.1.137	"Inositol phosphate metabolism";"PI3K Cascade";"Macroautophagy";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Phosphatidylinositol signaling system"
XP_049963989.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049938067.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049942227.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049960136.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7606	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_049947782.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049960923.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049964633.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"ECM proteoglycans";"Laminin interactions"
XP_049955364.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049961627.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049960382.1	10	Reactome: R-HSA-2453902;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;MetaCyc: PWY-7394;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;Reactome: R-HSA-975634	"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Neutrophil degranulation";"Retinoid metabolism and transport"
XP_049937479.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049961060.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Polymerase switching"
XP_049950419.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049939402.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049955247.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049963604.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049951848.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049958981.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049960769.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049948584.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_049961379.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049949270.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049963326.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049951720.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049963239.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049944680.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-450408	"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049962317.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049948995.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_049955852.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049943049.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049943490.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049952087.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049944088.1	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_049950260.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049961809.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049954227.1	7	MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism"
XP_049952821.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049962383.1	6	MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9;Reactome: R-HSA-71240;MetaCyc: PWY-6309	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_049958947.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049948838.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049937366.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049945839.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;MetaCyc: PWY-8051	"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PS";"Anandamide biosynthesis I"
XP_049960265.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049956300.1	11	Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-212436	"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway"
XP_049954826.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049939500.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_049960372.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049948930.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_049963977.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
XP_049961389.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5620924	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Kinesins";"Intraflagellar transport"
XP_049942588.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049945848.1	9	MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049950651.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049952088.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;MetaCyc: PWY-7511;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049956391.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049942080.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049950852.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049939184.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049957451.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049938219.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049950672.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049948881.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
YP_010417144.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049960402.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049958119.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049944251.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049955083.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049952379.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7291	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_049956925.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955066.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049942315.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_049942191.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049940243.1	24	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Kinesins";"Cilium Assembly";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors"
XP_049957543.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049961633.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049953723.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049963014.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049950301.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049955038.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-72163	"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway"
XP_049943662.1	12	KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9	"Pentose and glucuronate interconversions";"Galactose metabolism";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism"
XP_049937482.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049948929.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049941161.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049951889.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747	"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"RAF activation";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated"
XP_049940509.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-69166	"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate"
XP_049954117.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049960256.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049951643.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049938156.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049955585.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049953524.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049956134.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049943165.1	21	Reactome: R-HSA-9020702;Reactome: R-HSA-5357905;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-5602636;Reactome: R-HSA-975144;Reactome: R-HSA-1810476;Reactome: R-HSA-5603029;Reactome: R-HSA-168927;Reactome: R-HSA-1236974;Reactome: R-HSA-933543;Reactome: R-HSA-5607764;Reactome: R-HSA-5603027;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-937039;Reactome: R-HSA-1169091;Reactome: R-HSA-933542;Reactome: R-HSA-168638;Reactome: R-HSA-937041	"Interleukin-1 signaling";"Regulation of TNFR1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"IKBKB deficiency causes SCID";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"RIP-mediated NFkB activation via ZBP1";"IkBA variant leads to EDA-ID";"TICAM1, RIP1-mediated IKK complex recruitment";"ER-Phagosome pathway";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"CLEC7A (Dectin-1) signaling";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IRAK1 recruits IKK complex";"Activation of NF-kappaB in B cells";"TRAF6 mediated NF-kB activation";"NOD1/2 Signaling Pathway";"IKK complex recruitment mediated by RIP1"
XP_049939750.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556	"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport"
XP_049954430.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049941873.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049939293.1	10	Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-983168	"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049962849.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049959028.1	3	Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_049961014.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049950978.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049962978.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049947992.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049963148.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049953219.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049948010.1	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085	"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate"
XP_049961423.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483	"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs"
XP_049953699.1	5	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Formation of apoptosome"
XP_049941177.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-196025	"Clathrin-mediated endocytosis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions"
XP_049944155.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049950034.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049960245.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049941072.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"G alpha (z) signalling events"
XP_049961093.1	8	KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5394;Reactome: R-HSA-209905;MetaCyc: PWY-6133;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;KEGG: 00790+1.14.16.2	"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis II";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Folate biosynthesis"
XP_049957189.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049937383.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_049952216.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6807505	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes"
XP_049958807.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049944686.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA"
XP_049959446.1	14	Reactome: R-HSA-75109;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-6453	"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis"
XP_049949544.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049960374.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049943025.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049942925.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952527.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049955341.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049956255.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049950338.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049939825.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049948583.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049941297.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049962548.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_049940271.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049958605.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049964739.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049942087.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049941265.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049938525.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049962873.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049961764.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049937715.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049938052.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049955844.1	5	Reactome: R-HSA-1234158;Reactome: R-HSA-8849473;Reactome: R-HSA-1234174;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664	"Regulation of gene expression by Hypoxia-inducible Factor";"PTK6 Expression";"Cellular response to hypoxia";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation"
XP_049962678.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049946054.1	3	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation"
XP_049950959.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049939878.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049956979.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049953016.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049940651.1	10	Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7661;MetaCyc: PWY-7922;Reactome: R-HSA-162699;Reactome: R-HSA-913709	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose";"O-linked glycosylation of mucins"
XP_049955519.1	9	Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-110331	"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Cleavage of the damaged purine"
XP_049958864.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049947340.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049945779.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049946171.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049939820.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049964151.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049960649.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_049960875.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049939275.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)"
XP_049963007.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049951278.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049939235.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049956960.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049961186.1	6	Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;Reactome: R-HSA-446199;MetaCyc: PWY-922	"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I"
XP_049939912.1	6	KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_049960244.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_049949600.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049944236.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-8939243	"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Signal transduction by L1";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049963135.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049943250.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049959524.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049960024.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049950923.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049944234.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049948250.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049941359.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_049956930.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049960423.1	6	MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate"
XP_049939290.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764	"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling"
XP_049941765.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954600.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049941748.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049948596.1	17	Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-4086398;Reactome: R-HSA-5689880;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-1169091	"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ca2+ pathway";"Ub-specific processing proteases";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells"
XP_049959916.1	52	Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-72203	"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA"
XP_049938412.1	6	MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane"
XP_049959782.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049948025.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049956478.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_049953226.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049937547.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049938136.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950835.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049950213.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049937504.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049950853.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049955552.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_049957294.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049938080.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176408	"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase"
XP_049959373.1	6	Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_049956874.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877	"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Kinesins";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase"
XP_049940742.1	14	MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-4302	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)"
XP_049958809.1	8	Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"Ion channel transport";"ATP biosynthesis";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation"
XP_049942147.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049962422.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049941964.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049941668.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049940887.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082	"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"PPARA activates gene expression";"RORA activates gene expression"
XP_049950359.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049955478.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049961552.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-113418	"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex"
XP_049941488.1	40	Reactome: R-HSA-72203;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-112382	"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex"
XP_049950543.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049950215.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_049937747.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation"
XP_049961533.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049957170.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049938049.1	5	Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-6855	"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)"
XP_049949758.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049955847.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049953878.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5218920	"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability"
XP_049956035.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049938365.1	14	KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5057;MetaCyc: PWY-5108;MetaCyc: PWY-5101;MetaCyc: PWY-5078;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5103	"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Glucosinolate biosynthesis";"L-leucine degradation III";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-valine degradation II";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis II";"L-isoleucine degradation II";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III"
XP_049962219.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049946418.1	10	KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385	"Methane metabolism";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_049941572.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049959324.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049941063.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190861	"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly"
XP_049952627.1	3	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_049962729.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis"
XP_049942046.1	10	Reactome: R-HSA-5603041;Reactome: R-HSA-1236974;Reactome: R-HSA-168179;Reactome: R-HSA-6798695;Reactome: R-HSA-1461957;Reactome: R-HSA-5686938;Reactome: R-HSA-9637628;Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-168188	"IRAK4 deficiency (TLR2/4)";"ER-Phagosome pathway";"Toll Like Receptor TLR1:TLR2 Cascade";"Neutrophil degranulation";"Beta defensins";"Regulation of TLR by endogenous ligand";"Modulation by Mtb of host immune system";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Toll Like Receptor TLR6:TLR2 Cascade"
XP_049946186.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049947232.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049957956.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049952421.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049953203.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex"
XP_049947804.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_049961074.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049963858.1	20	KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6	"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism"
XP_049951093.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049951949.1	4	KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion"
XP_049942302.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049951817.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049947260.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049939274.1	5	MetaCyc: PWY-7918;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_049950817.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049941534.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049960038.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_049960674.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049949441.1	9	KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901	"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation"
XP_049943199.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049964786.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049941624.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049950979.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049939995.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017	"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6"
XP_049943269.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049939911.1	6	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation"
XP_049941724.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049957626.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049958826.1	4	Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;MetaCyc: PWY-6906	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Chitin derivatives degradation"
XP_049939674.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049943022.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960282.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049953963.1	6	KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17	"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation"
XP_049953622.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049962439.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_049961747.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049938893.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049961538.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954392.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049937301.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049948611.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling"
XP_049949522.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049960953.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis"
XP_049939464.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049947318.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_049957129.1	2	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
XP_049963424.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950392.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049963050.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_049960266.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049943455.1	9	MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis"
XP_049958023.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049963114.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_049960645.1	7	Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049955977.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling"
XP_049945167.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_049957921.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049946951.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049949414.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049950312.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049954798.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049960926.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049948159.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049947419.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049947152.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049959320.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049959568.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_049963046.1	33	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-8939236;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-167152	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_049963567.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049938546.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049948829.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049947302.1	11	Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049938340.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049958902.1	6	KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6364	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_049963128.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562	"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)"
XP_049938618.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436	"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049949805.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049947834.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049938631.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049953234.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_049964177.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696397	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049938989.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049959804.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_049950053.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049962612.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049948622.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049952130.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049940140.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049955632.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049954810.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049957833.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049955747.1	8	KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Th1 and Th2 cell differentiation";"Synthesis of PG";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"T cell receptor signaling pathway"
XP_049955894.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049948411.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_049958940.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049957127.1	2	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
XP_049941726.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049950888.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049958416.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_049955297.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_049946216.1	5	Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3	"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine metabolism"
XP_049962374.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049955612.1	5	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5189;Reactome: R-HSA-6798695	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation"
XP_049949029.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049962861.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049957743.1	18	MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism"
XP_049937597.1	5	MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_049963579.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049955629.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049942102.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049964766.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049937598.1	5	MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_049953678.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging"
XP_049942756.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049955131.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049958400.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_049959049.1	16	MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-2221;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1622	"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycolysis";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Methane metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)"
XP_049951302.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049950420.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049951677.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049963594.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049955561.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049953708.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_049959382.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049961629.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_049960121.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049950649.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049941641.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049953722.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049938128.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049949472.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_049954406.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049938899.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049958832.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Interferon gamma signaling";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049959447.1	14	Reactome: R-HSA-1483213;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053	"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II"
XP_049944149.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049954765.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049954460.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049960356.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049949535.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049937493.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049951126.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049941493.1	25	Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-1445148	"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049957868.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049959386.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049947838.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049951054.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049941143.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049943021.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049956604.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940998.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049960452.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049958088.1	31	MetaCyc: PWY-5971;MetaCyc: PWY-8012;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-7388;Reactome: R-HSA-163765;MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-4381;MetaCyc: PWY-5989	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Pederin biosynthesis";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)"
XP_049958004.1	4	Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_049940967.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049941073.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_049951160.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_049945237.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049942921.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049938379.1	14	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2022377;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049941510.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049961390.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Intraflagellar transport"
XP_049954647.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049953640.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049953903.1	8	Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_049962369.1	8	Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049963661.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049941564.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_049948889.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_049938692.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049962108.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750	"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6"
XP_049938250.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_049958291.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814	"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes"
XP_049948379.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049949928.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049952605.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049959396.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049956250.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049938221.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049939374.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049963580.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049952190.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049961578.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049953218.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049954069.1	12	MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-7343	"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Galactose metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I"
XP_049964790.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049942582.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049960482.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3232142	"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins"
XP_049959728.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049937844.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049952006.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049956307.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049960362.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049958206.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049940246.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049953229.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049960978.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049955275.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049940118.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
XP_049956296.1	29	Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167158	"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex"
XP_049960966.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049958530.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953888.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049960970.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049960082.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049963169.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs"
XP_049955682.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747	"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"RAF activation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated"
XP_049951583.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_049940840.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049962673.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049954985.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049964161.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_049943551.1	5	Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111469	"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response"
XP_049959350.1	31	MetaCyc: PWY-6282;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-7663;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-8047;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-5366;MetaCyc: PWY-7388;Reactome: R-HSA-163765;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-5971;MetaCyc: PWY-8012;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-5142;MetaCyc: PWY-7723	"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Bryostatin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"Pederin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence"
XP_049962882.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049939497.1	14	Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049950861.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049941732.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049956196.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049958125.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695	"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Neutrophil degranulation"
XP_049955475.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049941384.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049960290.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049939490.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049954008.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049950261.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049952866.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049963942.1	11	MetaCyc: PWY-7206;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism"
XP_049962617.1	10	MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-7328	"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Galactose metabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_049951194.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049959617.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049940504.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049950492.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049954059.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_049961513.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049960283.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049942524.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049953886.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049946172.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926	"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049952194.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049956666.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049964068.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049950880.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049956559.1	12	MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6122;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"One carbon pool by folate";"Purine metabolism";"Biotin transport and metabolism";"Purine metabolism"
XP_049956790.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049963144.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049953078.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049955516.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation"
XP_049950327.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049950598.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049952739.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049949219.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049948843.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049946820.1	11	Reactome: R-HSA-9008059;Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-389948;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-210990;Reactome: R-HSA-388841;Reactome: R-HSA-912694;Reactome: R-HSA-114604	"Interleukin-37 signaling";"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"PD-1 signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"PECAM1 interactions";"Costimulation by the CD28 family";"Regulation of IFNA signaling";"GPVI-mediated activation cascade"
XP_049954319.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049950132.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049940579.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049941315.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-1170546	"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling"
XP_049955496.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049951676.1	9	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049957580.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049939390.1	14	Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Arachidonic acid metabolism"
XP_049948499.1	57	Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553	"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs"
XP_049952048.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049959439.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049955998.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)"
XP_049952748.1	6	Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049951096.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049958478.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049958439.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049962430.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049949468.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049941693.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049963788.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954111.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049964865.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049950641.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049937507.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049938410.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049941823.1	31	MetaCyc: PWYG-321;MetaCyc: PWY-8047;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWY-6113;MetaCyc: PWY-6519;MetaCyc: PWY-5367;Reactome: R-HSA-75105;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7388;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41	"";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Superpathway of mycolate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Biotin metabolism"
XP_049954259.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_049954602.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049938325.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049951852.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049956108.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I"
XP_049955560.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049939857.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049963639.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049938326.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937450.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049954332.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_049949978.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_049937898.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049937546.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049947573.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049939824.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049955791.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049955090.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049941355.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049960486.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6837	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_049939241.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049950783.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6	"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049959791.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_049942498.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049962949.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_049953178.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049941548.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049963622.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_049955128.1	15	Reactome: R-HSA-9665249;Reactome: R-HSA-9665233;Reactome: R-HSA-9665251;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795	"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling"
XP_049940592.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049947199.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049938946.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049958921.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049954545.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-3214858;Reactome: R-HSA-381340	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation"
XP_049942255.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049939403.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049953618.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049947317.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049943041.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961647.1	5	MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
XP_049957899.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049961125.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258	"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of DVL"
XP_049939550.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049945312.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_049937412.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049964025.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049958620.1	10	MetaCyc: PWY-8067;MetaCyc: PWY-6839;MetaCyc: PWY-7510;MetaCyc: PWY-6682;MetaCyc: PWY-6322;MetaCyc: PWY-7769;KEGG: 00998+5.4.2.9;MetaCyc: PWY-5757;MetaCyc: PWY-7419;KEGG: 00440+5.4.2.9	"Methylphosphonate biosynthesis";"2-aminoethylphosphonate biosynthesis";"Rhizocticin A and B biosynthesis";"Dehydrophos biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Phosalacine biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Fosfomycin biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Phosphonate and phosphinate metabolism"
XP_049951572.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049952799.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_049953282.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049950617.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049953696.1	5	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_049960973.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049954579.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049937814.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049943178.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-73933	"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)"
XP_049947386.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049961535.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049939831.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049941259.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049962242.1	5	KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism"
XP_049946087.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049955978.1	10	KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276	"Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"
XP_049940332.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049953525.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049952265.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049942505.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049941180.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049949521.1	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049955835.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049952705.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049945574.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049960827.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_049938082.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049942418.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049941046.1	6	MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221	"Starch degradation V";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation III";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)"
XP_049959924.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049943013.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049964191.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049939893.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_049953170.1	7	Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-983168	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049948456.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-2173788	"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling"
XP_049952536.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049950032.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049944677.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA"
XP_049961954.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049964076.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049957028.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049943575.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049960030.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049963244.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria"
XP_049949120.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049952237.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049951274.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049959134.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049949321.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049952066.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049961586.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049952132.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049959279.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049939779.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049937692.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_049947912.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049960238.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
XP_049955109.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049940473.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049963220.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049962315.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis"
XP_049960203.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049938528.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049948626.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049957324.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049963960.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049953802.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049951850.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049960355.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049943556.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049951735.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049939978.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049937874.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049943861.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049952523.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049959601.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_049953307.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_049950125.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049951405.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049962972.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049946174.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_049953889.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049955997.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-5649702	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049940010.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951331.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049952679.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952108.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049938051.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049955672.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049953941.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049941535.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049939778.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049964020.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941113.1	4	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation";"Pyrophosphate hydrolysis"
XP_049944245.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049941745.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049960729.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049949474.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049937270.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049946490.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049956784.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-8948751	"Degradation of AXIN";"Ub-specific processing proteases";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity"
XP_049939968.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049954960.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049962517.1	11	MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-7456	"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation"
XP_049939183.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049937870.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049952113.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049940015.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_049943389.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049953692.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049949470.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_049942304.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180746	"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein"
XP_049943725.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049942811.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049962769.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_049938036.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049963767.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049955441.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049962426.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049937369.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049953721.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049950772.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_049954197.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049941363.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049943115.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049940409.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049941793.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049939822.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049964748.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_049960028.1	13	Reactome: R-HSA-2424491;MetaCyc: PWY-6367;Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-2871796;KEGG: 00562+3.1.4.11;Reactome: R-HSA-202433	"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated MAPK activation";"Inositol phosphate metabolism";"Generation of second messenger molecules"
XP_049963126.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049959948.1	8	KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086	"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_049963911.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049943435.1	29	Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782135	"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Meiotic recombination";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Dual incision in TC-NER"
XP_049963182.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049956903.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049943872.1	16	Reactome: R-HSA-5693579;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-9018519;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Estrogen-dependent gene expression";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049950644.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049953761.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049964712.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049950331.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049959580.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049953510.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_049949726.1	14	Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-1622;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-2201;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1	"Metabolism of folate and pterines";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycine betaine degradation I";"Folate transformations I";"Photorespiration ";"Cyanoamino acid metabolism";"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism"
XP_049948894.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14	"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_049948601.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049958382.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049941622.1	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049958328.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049960689.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049946458.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049951685.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644	"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair"
XP_049939803.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049950661.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049951905.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049941744.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049956796.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049960422.1	6	KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820	"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)"
XP_049950795.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049953849.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049952115.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049958021.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049952626.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_049958429.1	17	MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-6644;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1	"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine catabolism";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Pyrimidine metabolism"
XP_049953151.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049937676.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_049959711.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049943568.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049950075.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049946004.1	6	MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism"
XP_049954250.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049964026.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049963816.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049952504.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049947928.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049955150.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_049962084.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049963992.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049958924.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049957865.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049938529.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049955630.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049960353.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049941245.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049961205.1	12	Reactome: R-HSA-177929;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-75893;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-5362798	"Signaling by EGFR";"Growth hormone receptor signaling";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"TNF signaling";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Release of Hh-Np from the secreting cell"
XP_049951045.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049960239.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049951265.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555	"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events"
XP_049938513.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049951903.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049960153.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049937566.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049954327.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_049950302.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049945402.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049953439.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049963727.1	11	KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-381	"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)"
XP_049964902.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049949525.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049943057.1	4	KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism"
XP_049947699.1	7	MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204	"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_049946578.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049952730.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049944182.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049953706.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_049947552.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049960487.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049964658.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049956106.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_049958612.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-9610379	"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"HCMV Late Events"
XP_049958044.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049953702.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049943036.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049949119.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049956355.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049955826.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049952400.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049949759.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049938153.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049959275.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049951037.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049940363.1	5	KEGG: 00240+2.7.1.21;KEGG: 00983+2.7.1.21;MetaCyc: PWY-7199;Reactome: R-HSA-73614;Reactome: R-HSA-69205	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"G1/S-Specific Transcription"
XP_049956964.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049942861.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049939492.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049955498.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049944675.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72662	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_049955089.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049952242.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049939689.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049946000.1	6	KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_049941807.1	10	MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041	"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle"
XP_049940434.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049942551.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6807878	"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"COPI-mediated anterograde transport"
XP_049937908.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049940304.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_049943960.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_049961995.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049940542.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049955279.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049953759.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049949250.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049939388.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_049962283.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049957460.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049953494.1	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_049953779.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049953962.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049960821.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464	"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins"
XP_049941850.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951171.1	11	KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;MetaCyc: PWY-8052	"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis"
XP_049937406.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049964663.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049963227.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049951981.1	12	MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4	"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism"
XP_049948434.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049944218.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049964753.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_049954854.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049955290.1	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-5531	"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_049947200.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941750.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049960222.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049951493.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049957576.1	7	MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698;MetaCyc: PWY-5697	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_049939913.1	6	MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism"
XP_049941729.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049962366.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432722	"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis"
XP_049947440.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049943664.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_049950654.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049940635.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049948013.1	6	MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis"
XP_049956540.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049955849.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049963271.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5870;KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5856	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_049962000.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952684.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049956811.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049956677.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049937408.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049961826.1	4	MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases"
XP_049948257.1	13	Reactome: R-HSA-5357956;Reactome: R-HSA-975163;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325	"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_049961721.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_049958446.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049951688.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049962450.1	11	Reactome: R-HSA-983231;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213	"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs"
XP_049954077.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049961545.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049955136.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049948616.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049960236.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049956669.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049957873.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA"
XP_049942406.1	15	Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-179409	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A"
XP_049964077.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049961162.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_049946013.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049941742.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049946217.1	5	KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage"
XP_049953462.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049940540.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049949649.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049949097.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049963350.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049942681.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049949352.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049941834.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7587	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)"
XP_049937483.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049945960.1	7	Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232	"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_049963140.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049943158.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049937793.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049938419.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049964192.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049955787.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049946643.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049949324.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049958369.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049946085.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049941105.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049956187.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049954816.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049954144.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049940565.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049938237.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049953949.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049959407.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049949976.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_049953887.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049960884.1	17	Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048	"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_049942421.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_049953298.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049948189.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049952763.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049946356.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049938263.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599	"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases"
XP_049939777.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049959633.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049964271.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049959368.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049940501.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049958724.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049938627.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049954095.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_049958275.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_049946153.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049960240.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria"
XP_049960261.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049964382.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049954139.1	24	Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-500657	"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"G-protein activation";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Ca2+ pathway";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors"
XP_049958841.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948	"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants"
XP_049938009.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-901032	"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
XP_049955611.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188	"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049941218.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049941627.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049957728.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_049938173.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049953594.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113	"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049959234.1	4	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;Reactome: R-HSA-379716	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation"
XP_049956817.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049950285.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_049956989.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_049953217.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049950489.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049961067.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049941342.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049964682.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049960051.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049952311.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049946310.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049959067.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-193048;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049962655.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_049950662.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049950334.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049954524.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_049964730.1	4	MetaCyc: PWY-5030;Reactome: R-HSA-70921;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5028	"L-histidine degradation III";"Histidine catabolism";"Histidine metabolism";"L-histidine degradation II"
XP_049953758.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049961625.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049963925.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
YP_010417145.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049956636.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_049947576.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049956000.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049961342.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_049954519.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049948538.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049959843.1	24	Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-420092	"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G-protein activation";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Ca2+ pathway";"G alpha (i) signalling events";"Glucagon-type ligand receptors"
XP_049963430.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049944146.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049963286.1	8	MetaCyc: PWY-7391;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_049948266.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049941602.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049952773.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_049945993.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049943991.1	29	Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565	"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Meiotic recombination";"HSF1 activation";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049941338.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_049943492.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049941738.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049937896.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049941045.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049944376.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049951215.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049939727.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049940063.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049953152.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049961523.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049953325.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_049961061.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation"
XP_049946455.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049950665.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049963247.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-606279	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049942225.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049939787.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049960861.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049960704.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049952916.1	4	Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241	"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import"
XP_049950129.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_049960992.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5689880	"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases"
XP_049940685.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049942081.1	6	MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis"
XP_049941895.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049963048.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_049956808.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049937330.1	14	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6811436	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049938821.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049964824.1	9	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-69656;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription"
XP_049950339.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049946307.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049953233.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_049942036.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I"
XP_049963750.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049960792.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049964659.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049963290.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049964622.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_049943214.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049959276.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049963260.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049958824.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-399719	"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Interferon gamma signaling";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors"
XP_049952569.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049941255.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610785	"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome"
XP_049952069.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049964745.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049962240.1	5	KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937	"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Iron uptake and transport"
XP_049958459.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951882.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_049943327.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049960540.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049943968.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_049944175.1	29	Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-912446;Reactome: R-HSA-5656121	"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Meiotic recombination";"Translesion synthesis by POLI"
XP_049954410.1	7	MetaCyc: PWY-3841;Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00790+1.5.1.3	"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"G1/S-Specific Transcription";"Folate biosynthesis"
XP_049940217.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_049947143.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049960280.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049952762.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049950366.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049959858.1	52	Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-1236974	"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway"
XP_049960083.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049958396.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040;MetaCyc: PWY-8072	"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"Alanine racemization"
XP_049953216.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049941254.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049954606.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049953675.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_049956132.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049963015.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049941533.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049960165.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049956295.1	29	Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_049947234.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049941102.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_049950712.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_049937484.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049958535.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_049959579.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049956336.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049957387.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049952771.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049953555.1	19	Reactome: R-HSA-6798695;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-163765;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-6969;Reactome: R-HSA-75105	"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis"
XP_049959378.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049961221.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049953308.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049953726.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049962608.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049951772.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-9610379	"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"HCMV Late Events"
XP_049938245.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049943565.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049940189.1	8	MetaCyc: PWY-7199;MetaCyc: PWY-6556;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;Reactome: R-HSA-6798695	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation"
XP_049955619.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049955836.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-171306	"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends"
XP_049949293.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_049960006.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049943959.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_049938526.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049946347.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_049940280.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_049939561.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049953691.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049938258.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_049964698.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_049938165.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049957528.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049961886.1	8	KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis"
XP_049942238.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955110.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Polymerase switching"
XP_049953302.1	15	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049955637.1	24	Reactome: R-HSA-9010642;Reactome: R-HSA-163560;KEGG: 04150+2.7.11.11;Reactome: R-HSA-164378;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-8963896;Reactome: R-HSA-9634600;Reactome: R-HSA-5621575;Reactome: R-HSA-392517;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-8853659;Reactome: R-HSA-5610780;Reactome: R-HSA-111931;Reactome: R-HSA-163615;Reactome: R-HSA-163358;Reactome: R-HSA-4420097	"ROBO receptors bind AKAP5";"Triglyceride catabolism";"mTOR signaling pathway";"PKA activation in glucagon signalling";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"HDL assembly";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"CD209 (DC-SIGN) signaling";"Rap1 signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"RET signaling";"Degradation of GLI1 by the proteasome";"PKA-mediated phosphorylation of CREB";"PKA activation";"PKA-mediated phosphorylation of key metabolic factors";"VEGFA-VEGFR2 Pathway"
XP_049940120.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049942860.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689	"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex"
XP_049949319.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049959451.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049955823.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036	"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_049957541.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_049952318.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049949466.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049949498.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049953464.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049947390.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_049957477.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049949628.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049960133.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049952182.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049939254.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049938380.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049953833.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049942436.1	17	Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-4381;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2	"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Glyoxylate assimilation";"Pyruvate metabolism";"Propanoate metabolism";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Aflatoxin biosynthesis"
XP_049937281.1	9	KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061	"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I"
XP_049954212.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049942313.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049946065.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049958815.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis"
XP_049946106.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049951368.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049941066.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_049959859.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis"
XP_049964703.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049941953.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049959133.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049956972.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049956169.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049960399.1	7	KEGG: 00730+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15	"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism"
XP_049964746.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_049937646.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049959310.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049956609.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049958844.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049944682.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-450408	"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049954198.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049953260.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049961077.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049951070.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049946515.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049957211.1	18	MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms"
XP_049937297.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049963474.1	34	Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-9639288;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-191859	"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Amino acids regulate mTORC1";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"snRNP Assembly"
XP_049943157.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049937737.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049964906.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049948686.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049953335.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049949349.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049961402.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049939765.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_049938091.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_049960896.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049952696.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"Galactose metabolism";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)"
XP_049945814.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049959280.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049950686.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049960360.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049949007.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049953509.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_049963330.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_049964110.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049938033.1	5	Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571	"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation"
XP_049955283.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049945675.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049960044.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049951634.1	25	Reactome: R-HSA-8939236;Reactome: R-HSA-8939247;Reactome: R-HSA-8940973;Reactome: R-HSA-8939256;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-8951936;Reactome: R-HSA-8877330;Reactome: R-HSA-8931987;Reactome: R-HSA-8939902;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8939246;Reactome: R-HSA-8949275;Reactome: R-HSA-8941333;Reactome: R-HSA-9616222;Reactome: R-HSA-8939243;Reactome: R-HSA-8941326;Reactome: R-HSA-8941284;Reactome: R-HSA-8941858;Reactome: R-HSA-8939245;Reactome: R-HSA-8935964;Reactome: R-HSA-8936459;Reactome: R-HSA-8941332;Reactome: R-HSA-8939242	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 regulates p14-ARF";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates bone development";"RUNX2 regulates chondrocyte maturation";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes"
XP_049949720.1	10	Reactome: R-HSA-9637628;Reactome: R-HSA-5602498;Reactome: R-HSA-1461957;Reactome: R-HSA-6798695;Reactome: R-HSA-5686938;Reactome: R-HSA-1236974;Reactome: R-HSA-168179;Reactome: R-HSA-5603041;Reactome: R-HSA-168188;Reactome: R-HSA-166058	"Modulation by Mtb of host immune system";"MyD88 deficiency (TLR2/4)";"Beta defensins";"Neutrophil degranulation";"Regulation of TLR by endogenous ligand";"ER-Phagosome pathway";"Toll Like Receptor TLR1:TLR2 Cascade";"IRAK4 deficiency (TLR2/4)";"Toll Like Receptor TLR6:TLR2 Cascade";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_049940395.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049944887.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049955086.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049941878.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049951859.1	8	Reactome: R-HSA-3270619;KEGG: 00790+4.1.99.22;Reactome: R-HSA-6798695;Reactome: R-HSA-947581;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;MetaCyc: PWY-6823	"IRF3-mediated induction of type I IFN";"Folate biosynthesis";"Neutrophil degranulation";"Molybdenum cofactor biosynthesis";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Molybdenum cofactor biosynthesis"
XP_049953673.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)"
XP_049957179.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049962136.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"Thermogenesis"
XP_049955851.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049962372.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049942477.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049947737.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049949131.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049949576.1	5	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-446388	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_049941776.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049939103.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049955944.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049953757.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049963187.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049960925.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049960795.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049957625.1	9	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection"
XP_049939441.1	18	MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-5362517;KEGG: 00010+1.8.1.4;Reactome: R-HSA-6783984	"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"Citrate cycle (TCA cycle)";"Glycine, serine and threonine metabolism";"Lysine degradation";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Propanoate metabolism";"Lysine catabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Glycine degradation"
XP_049952505.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_049960037.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049958795.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism"
XP_049941459.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049938890.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049953465.1	16	MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.4;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5749	"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Itaconate degradation"
XP_049944506.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049941894.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049951828.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049955099.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049942164.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049960582.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049947635.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049938181.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049949279.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049938101.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_049964442.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049944076.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049945868.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049958374.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049944229.1	9	MetaCyc: PWY-8086;Reactome: R-HSA-196780;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-70263	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis"
XP_049951032.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049953262.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049941420.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049956958.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049954318.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049948842.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049963880.1	13	Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Collagen chain trimerization";"Anchoring fibril formation";"ECM proteoglycans";"Collagen degradation"
XP_049940934.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049938118.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049940061.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049957973.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049957478.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049963640.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049957975.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049960648.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049937453.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049942112.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049961343.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_049952378.1	20	MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337	"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_049937417.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049964359.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049964816.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049959184.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049960398.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049938771.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_049962986.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_049949435.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049939556.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049948355.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049951121.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049941442.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049940506.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049955108.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049953389.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049953683.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049959347.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049960857.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049953460.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049960873.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049953391.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_049943419.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049956935.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049955950.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049963385.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049962875.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049954411.1	7	Reactome: R-HSA-1474151;MetaCyc: PWY-3841;Reactome: R-HSA-69205;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-196757	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines"
XP_049940477.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049954399.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-983168	"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049949631.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049947835.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049958501.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049962731.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049958803.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049949996.1	8	KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6580	"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_049955742.1	9	Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932	"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules"
XP_049956393.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049956380.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083	"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions"
XP_049947952.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049946576.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049954172.1	13	KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-4085001;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670	"Glycosaminoglycan degradation";"HS-GAG degradation";"Galactose metabolism";"Neutrophil degranulation";"Keratan sulfate degradation";"Sialic acid metabolism";"Other glycan degradation";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis"
XP_049964022.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049945759.1	6	MetaCyc: PWY-6606;MetaCyc: PWY-7442;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-6608	"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III"
XP_049957809.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049963312.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049956800.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049962329.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049959509.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049939368.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049954470.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Activation of RAC1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049962289.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049949184.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049950247.1	9	KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis"
XP_049952142.1	11	Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Cytosolic sensors of pathogen-associated DNA";"mTOR signaling pathway";"Thermogenesis";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049944003.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-6453	"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis"
XP_049938620.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation"
XP_049950430.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049954676.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049946046.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-606279	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049940207.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049937395.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)"
XP_049954011.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation"
XP_049948567.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049963432.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049946294.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049949626.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049960864.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049954214.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_049953231.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049959608.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049962258.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049938519.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_049959755.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-68962	"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Activation of the pre-replicative complex"
XP_049954229.1	7	KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6122	"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_049956232.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049958949.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049956118.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049957172.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049949273.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049952525.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049957761.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049937677.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_049959842.1	24	Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-381676	"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Ca2+ pathway";"Glucagon-type ligand receptors";"G-protein activation";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049944191.1	17	Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-3270619;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-1834949	"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"IRF3-mediated induction of type I IFN";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Cytosolic sensors of pathogen-associated DNA"
XP_049943734.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_049954990.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism"
XP_049939332.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049950151.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049947701.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049952313.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049942237.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049949975.1	7	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-5696394;Reactome: R-HSA-201722;Reactome: R-HSA-606279	"HATs acetylate histones";"UCH proteinases";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049949469.1	14	MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-4302;Reactome: R-HSA-71403;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1	"Methylaspartate cycle";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Butanoate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)"
XP_049942234.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049949423.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5610785	"Hedgehog 'on' state";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome"
XP_049959300.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049951254.1	13	KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-7112;Reactome: R-HSA-196836;MetaCyc: PWY-7533	"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis"
XP_049945823.1	15	Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-3769402	"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex"
XP_049948392.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049939574.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_049962969.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049957331.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049942305.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941019.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049957866.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049956789.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_049938371.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937661.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049963249.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049943677.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049937495.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049940333.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049958945.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049939521.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_049951980.1	18	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;Reactome: R-HSA-1482839	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE"
XP_049951051.1	4	KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_049960639.1	6	MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118	"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle"
XP_049964414.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049937505.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049944252.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049962736.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049938476.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes"
XP_049959381.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049941669.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049939488.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049944244.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049964793.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049948017.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049941828.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941757.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049945598.1	12	Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-350054	"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Notch-HLH transcription pathway"
XP_049956073.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_049951635.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049956099.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049959527.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049962741.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049961003.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049949012.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049961062.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation"
XP_049952526.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049954200.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049963658.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049939947.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049942699.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_049961510.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049950143.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_049939513.1	7	Reactome: R-HSA-8950505;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049956383.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049942235.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049948615.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049958405.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049959525.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049940906.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049953908.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_049951266.1	13	KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-2261;Reactome: R-HSA-196836;MetaCyc: PWY-7533	"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis"
XP_049955999.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-5696397	"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049951504.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-3371571	"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"HSF1-dependent transactivation"
XP_049949839.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049949813.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-212436	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway"
XP_049950819.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049963124.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049950476.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049955543.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_049962376.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_049960504.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049943406.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955911.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049940042.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049963821.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_049941467.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049937718.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049960840.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_049950966.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049960241.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-139915	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria"
XP_049939642.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049963457.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049955922.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049963657.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049962895.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049959538.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049956580.1	17	MetaCyc: PWY-6611;MetaCyc: PWY-6620;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-5532;MetaCyc: PWY-4202;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1	"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Purine catabolism";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Salinosporamide A biosynthesis";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism"
XP_049939553.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_049962220.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049950542.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049960413.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049951038.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049949326.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227	"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA"
XP_049957773.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049952109.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049958504.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_049938367.1	14	KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5078;MetaCyc: PWY-5103;MetaCyc: PWY-5108;MetaCyc: PWY-7767;MetaCyc: PWY-5076;MetaCyc: PWY-5057;MetaCyc: PWY-5104;KEGG: 00280+2.6.1.42;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00966+2.6.1.42	"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine degradation II";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"L-leucine degradation III";"L-valine degradation II";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine degradation";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"Glucosinolate biosynthesis"
XP_049942286.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Macroautophagy";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049941752.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049938411.1	6	MetaCyc: PWY-6367;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_049959945.1	8	KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-6901	"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation"
XP_049957457.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954038.1	7	Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205	"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049950423.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049964103.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_049964779.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049949155.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049949924.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049949617.1	10	MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9	"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Metabolism of folate and pterines";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes"
XP_049954416.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049951514.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049962015.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950445.1	6	KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020	"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import"
XP_049938141.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049942501.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049948872.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049956938.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049955942.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049955190.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049947153.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049943557.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049959339.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_049964768.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049950660.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049960670.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049939759.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation"
XP_049960268.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049946584.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049957539.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_049949734.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049939948.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049938177.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049960977.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049955670.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049954205.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049938211.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049954029.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049961777.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049961174.1	24	Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148	"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Kinesins";"Cilium Assembly";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049960405.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049952816.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948	"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants"
XP_049950903.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049945831.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049953737.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049941470.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049944750.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049937411.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049953444.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_049955846.1	5	Reactome: R-HSA-1234158;Reactome: R-HSA-8849473;Reactome: R-HSA-1234174;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176	"Regulation of gene expression by Hypoxia-inducible Factor";"PTK6 Expression";"Cellular response to hypoxia";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049937516.1	5	KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22	"Sphingolipid metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism"
XP_049949951.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_049939369.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049951238.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049956667.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049946170.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_049941197.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049964233.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049955923.1	8	Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Signaling by Hippo";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049949984.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_049962676.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148;Reactome: R-HSA-6798695	"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation"
XP_049940416.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049958786.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism"
XP_049961157.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_049955855.1	7	Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661	"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation"
XP_049938760.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049947827.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049951976.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049956623.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049957409.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_049950711.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049961199.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049962739.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049951731.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952819.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695	"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation"
XP_049955493.1	7	Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17	"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049963235.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049943982.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049938200.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_049956221.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049963946.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049960160.1	6	KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane"
XP_049959194.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049951039.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049961058.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_049941034.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049952832.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049953317.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049951190.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_049963853.1	5	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;Reactome: R-HSA-75109	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis"
XP_049958491.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049949599.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049952137.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049964648.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049941589.1	10	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7805;MetaCyc: PWY-7807;MetaCyc: PWY-7656;Reactome: R-HSA-71737;Reactome: R-HSA-9640463;KEGG: 00190+3.6.1.1;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Spodoptera littoralis pheromone biosynthesis";"Pyrophosphate hydrolysis";"Wax biosynthesis";"Oxidative phosphorylation";"Cutin, suberine and wax biosynthesis"
XP_049940197.1	33	Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-112382;Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-72086;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of RNA Pol II elongation complex";"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049945449.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049937909.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049941491.1	25	Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Kinesins";"Cilium Assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049953891.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_049937303.1	10	KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23	"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"HS-GAG degradation";"Galactose metabolism"
XP_049953077.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049941323.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049943163.1	21	Reactome: R-HSA-1169091;Reactome: R-HSA-933542;Reactome: R-HSA-168638;Reactome: R-HSA-937041;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-937039;Reactome: R-HSA-5357956;Reactome: R-HSA-5603027;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-933543;Reactome: R-HSA-168927;Reactome: R-HSA-1810476;Reactome: R-HSA-5603029;Reactome: R-HSA-975144;Reactome: R-HSA-5602636;Reactome: R-HSA-445989;Reactome: R-HSA-5357905;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"TRAF6 mediated NF-kB activation";"NOD1/2 Signaling Pathway";"IKK complex recruitment mediated by RIP1";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IRAK1 recruits IKK complex";"TNFR1-induced NFkappaB signaling pathway";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TICAM1, RIP1-mediated IKK complex recruitment";"RIP-mediated NFkB activation via ZBP1";"IkBA variant leads to EDA-ID";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IKBKB deficiency causes SCID";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of TNFR1 signaling";"FCERI mediated NF-kB activation";"Interleukin-1 signaling"
XP_049952058.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049949974.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049962967.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049949655.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049962139.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049937480.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049951179.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049963653.1	13	Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-3000157;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178	"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"NCAM1 interactions";"Laminin interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Integrin cell surface interactions";"Collagen degradation";"Collagen chain trimerization";"Anchoring fibril formation";"ECM proteoglycans"
XP_049950010.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_049952381.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7291	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_049964788.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049954285.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049943137.1	7	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16	"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_049963329.1	3	KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691	"Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I"
XP_049950886.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049959817.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049954838.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049960651.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_049958476.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049958312.1	11	MetaCyc: PWY-7185;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7821;MetaCyc: PWY-6596;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5	"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Pyrimidine metabolism"
XP_049954786.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049942416.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049952701.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_049958823.1	4	MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049948357.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049943414.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049963167.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049940303.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_049960124.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049938931.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049955593.1	10	MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15	"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049946349.1	6	MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism";"Vitamin B6 metabolism";"Serine biosynthesis"
XP_049947828.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049956421.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049961577.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049941253.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049954796.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049950484.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049954064.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049962625.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049943328.1	9	KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049940181.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049958103.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049957829.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049953707.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049954325.1	10	MetaCyc: PWY-6369;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-4661	"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_049939856.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049949226.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049955970.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049961200.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_049946438.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049955512.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049959562.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_049943405.1	5	MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_049957812.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049949000.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049948377.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049938070.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049949285.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049939304.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049954379.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_049961235.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049952859.1	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6724	"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation II"
XP_049954046.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049959997.1	13	MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-6613;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate polyglutamylation";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes"
XP_049952007.1	13	Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1	"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway"
XP_049943980.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049962159.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049939720.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_049962425.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049964848.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049963496.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049951197.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049960223.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049960739.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-901032	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)"
XP_049942137.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_049954542.1	10	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RSK activation"
XP_049944069.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049937414.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950298.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049956506.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"Estrogen-dependent gene expression";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation"
XP_049957793.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955132.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049962204.1	12	MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-6672;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1	"Chitin degradation to ethanol";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis"
XP_049937905.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049952704.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049941598.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049953290.1	14	Reactome: R-HSA-196757;MetaCyc: PWY-1622;MetaCyc: PWY-2161;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1	"Metabolism of folate and pterines";"Formaldehyde assimilation I (serine pathway)";"Folate polyglutamylation";"Methane metabolism";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate transformations I";"Cyanoamino acid metabolism";"One carbon pool by folate"
XP_049964796.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049960269.1	37	Reactome: R-HSA-2132295;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-983170;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-204005;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159230	"MHC class II antigen presentation";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"COPII-mediated vesicle transport";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA"
XP_049959907.1	52	Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-749476;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-75953	"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation"
XP_049946633.1	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40	"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Entner-Doudoroff pathway I";"Purine metabolism"
XP_049939652.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049953845.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049953735.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049937986.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940855.1	4	Reactome: R-HSA-5679001;Reactome: R-HSA-382556;Reactome: R-HSA-189483;MetaCyc: PWY-6972	"Defective ABCC2 causes Dubin-Johnson syndrome";"ABC-family proteins mediated transport";"Heme degradation";"Oleandomycin activation/inactivation"
XP_049958733.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049950889.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049960365.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049953899.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_049950365.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049948495.1	32	Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-113418	"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex"
XP_049940134.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049964760.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049962682.1	7	KEGG: 00071+1.3.8.7;Reactome: R-HSA-77348;Reactome: R-HSA-77346;Reactome: R-HSA-1989781;Reactome: R-HSA-77288;MetaCyc: PWY-7094;KEGG: 00280+1.3.8.7	"Fatty acid degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"PPARA activates gene expression";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid salvage";"Valine, leucine and isoleucine degradation"
XP_049941098.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049957835.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049964754.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_049960945.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_049939525.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-69091	"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching"
XP_049954230.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049954116.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228	"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix"
XP_049959348.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_049964319.1	6	Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2160916	"HS-GAG degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Hyaluronan uptake and degradation"
XP_049963087.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049942180.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049947833.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049957437.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049945962.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_049939670.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049940798.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049960660.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049964001.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049949983.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_049948687.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049944743.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049950814.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049962808.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-205043	"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus"
XP_049939206.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049945975.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049952996.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049956109.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049963959.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049958738.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_049946445.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049943913.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049949727.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049941320.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049951275.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049946092.1	15	MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-6142	"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis";"Entner-Doudoroff pathway I";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049964197.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049958186.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049962085.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049952030.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049961488.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049937518.1	20	MetaCyc: PWY-7220;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7198;Reactome: R-HSA-380270;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7197	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of mitotic centrosome proteins and complexes";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_049937405.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049954234.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049941179.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_049956923.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955130.1	15	Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9665251;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285	"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2"
XP_049949287.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049956231.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049951726.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960930.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049941047.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049959274.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049942254.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049953105.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049962297.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049954976.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049945847.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_049963423.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049944090.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049940600.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_049943038.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049943047.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049944063.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049956074.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_049958227.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_049949817.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049937862.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049940196.1	33	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-167152	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_049949214.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049961519.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049959611.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049949334.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049949353.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049960991.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5689880	"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Ub-specific processing proteases"
XP_049946519.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049958022.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_049958069.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_049944765.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049940301.1	4	KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism"
XP_049939376.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049939821.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049959539.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049939375.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049960659.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049951533.1	17	Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-139915;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-111448;Reactome: R-HSA-2559585;Reactome: R-HSA-9616222;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1912408	"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Activation of PUMA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of NOXA and translocation to mitochondria";"Oncogene Induced Senescence";"Transcriptional regulation of granulopoiesis";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Pre-NOTCH Transcription and Translation"
XP_049948914.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049950099.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
XP_049948155.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049959096.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049950803.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049937449.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049961485.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049939943.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049942271.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049944830.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049963592.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049949271.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049959535.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049963181.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049939378.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049962778.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-381426	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049959029.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049941350.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_049954310.1	16	Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-9009391;Reactome: R-HSA-512988;Reactome: R-HSA-912526;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-912631;Reactome: R-HSA-416476;Reactome: R-HSA-8853659;Reactome: R-HSA-194840	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Extra-nuclear estrogen signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin receptor SHC signaling";"Interleukin-7 signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Regulation of signaling by CBL";"G alpha (q) signalling events";"RET signaling";"Rho GTPase cycle"
XP_049944230.1	9	Reactome: R-HSA-196780;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency"
XP_049946574.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049956588.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950674.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049942725.1	10	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722	"Thermogenesis";"Ub-specific processing proteases";"Human cytomegalovirus infection";"HATs acetylate histones";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex"
XP_049951209.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049938394.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049957312.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_049948102.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049947314.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049950297.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049960730.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049941908.1	18	MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788	"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PC"
XP_049963054.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049954797.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049937745.1	8	MetaCyc: PWY-5723;Reactome: R-HSA-8950505;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;MetaCyc: PWY-1861;Reactome: R-HSA-163754;Reactome: R-HSA-6791462	"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P"
XP_049950663.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_049955882.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049964656.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049938883.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937545.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049938515.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049959303.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52	"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049958031.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_049953533.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049959847.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling"
XP_049937640.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049963578.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049955127.1	15	Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795	"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling"
XP_049945621.1	3	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049950706.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_049955292.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-5531;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism"
XP_049959739.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049937396.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation"
XP_049959597.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER"
XP_049963987.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049950529.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049952319.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049947477.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049941996.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205	"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription"
XP_049956081.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049953828.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049954637.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049937421.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049948548.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049940102.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_049946596.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049952952.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049954601.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049943456.1	9	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Inositol phosphate metabolism"
XP_049952830.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888	"VLDL clearance";"Scavenging by Class H Receptors";"LDL clearance";"VLDL assembly";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron remodeling";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Chylomicron clearance";"Scavenging by Class F Receptors";"Chylomicron assembly"
XP_049962597.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_049948190.1	8	Reactome: R-HSA-4641263;Reactome: R-HSA-5340588;Reactome: R-HSA-4608870;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398;Reactome: R-HSA-8856828;Reactome: R-HSA-373080	"Regulation of FZD by ubiquitination";"RNF mutants show enhanced WNT signaling and proliferation";"Asymmetric localization of PCP proteins";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway";"Clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)"
XP_049937740.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049946575.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049949004.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049961194.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553	"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of DVL";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs"
XP_049960716.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049940064.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049958606.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049962737.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_049941194.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049963587.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049943111.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049939439.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT"
XP_049939780.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049950035.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049958734.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049960969.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049957788.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049963328.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049951834.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049963705.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049945678.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049956171.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049958739.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_049938969.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049942529.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049963459.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049960337.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_049942370.1	19	MetaCyc: PWY-6728;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-1622;Reactome: R-HSA-71403;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-561;MetaCyc: PWY-6969	"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049946592.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049938718.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049950696.1	1	Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049941052.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049959095.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049958766.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_049941469.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049946344.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049939906.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049951869.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049953155.1	8	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6783310;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Fanconi Anemia Pathway";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049955878.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049952875.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_049963183.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049959902.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049959560.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_049941413.1	5	Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955	"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049953680.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_049939239.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_049964900.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049959522.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_049962445.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049941775.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049940816.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_049949647.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049963720.1	11	MetaCyc: PWY-381;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2	"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism"
XP_049960519.1	5	MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317	"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_049955073.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049956170.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049960641.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-163560	"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Triglyceride catabolism"
XP_049952531.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049960009.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_049951571.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049946483.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049955563.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049957795.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950447.1	6	KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism"
XP_049946152.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049938856.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049958076.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_049953865.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049960371.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049937397.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_049942908.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049941829.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049964624.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049951234.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049949499.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049961664.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049950930.1	6	Reactome: R-HSA-8862803;Reactome: R-HSA-2151201;Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species"
XP_049947412.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049939693.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_049958215.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083	"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions"
XP_049941648.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049937710.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049953332.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049937811.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling"
XP_049937320.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_049963287.1	8	MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis"
XP_049952559.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049960042.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049943570.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049960797.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049937723.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049956199.1	7	MetaCyc: PWY-8088;MetaCyc: PWY-2942;MetaCyc: PWY-5097;Reactome: R-HSA-389661;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941	"Dipicolinate biosynthesis";"L-lysine biosynthesis III";"L-lysine biosynthesis VI";"Glyoxylate metabolism and glycine degradation";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis II"
XP_049937830.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049951829.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049942437.1	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Aflatoxin biosynthesis"
XP_049950044.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975	"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA"
XP_049961288.1	14	Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397	"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049963647.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins"
XP_049963269.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049950699.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049957243.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049941270.1	3	Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129	"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)"
XP_049956554.1	12	Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_049951959.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049940023.1	3	Reactome: R-HSA-8849471;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049961856.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049937609.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049939216.1	10	KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11	"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism"
XP_049960871.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049940510.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-110362	"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair"
XP_049954627.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243	"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049944068.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049949686.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Kinesins";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049937876.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049956698.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_049958523.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959231.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049946019.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049938329.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_049960498.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049957066.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049947557.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049940254.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-879415	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling"
XP_049947896.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycolysis";"Purine metabolism"
XP_049962451.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-69231	"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1"
XP_049959887.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049961167.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049957897.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049950063.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049958804.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism"
XP_049950695.1	1	Reactome: R-HSA-73943	"Reversal of alkylation damage by DNA dioxygenases"
XP_049951450.1	9	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"G1/S-Specific Transcription";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation"
XP_049938154.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049947366.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049961574.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049947208.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049959504.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049964800.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049961344.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_049942300.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954225.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-1632852	"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy"
XP_049957624.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049956586.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049943001.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049959308.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049958562.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_049954953.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049937424.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049955579.1	4	KEGG: 00340+4.3.1.3;MetaCyc: PWY-5030;Reactome: R-HSA-70921;MetaCyc: PWY-5028	"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism";"L-histidine degradation II"
XP_049963207.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049947360.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_049954794.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049964035.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_049964356.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049946179.1	7	MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis"
XP_049951263.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049944181.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049963789.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049954914.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_049947246.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049943997.1	56	Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534	"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4"
XP_049946582.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049954413.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049956668.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049947158.1	6	MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-7356	"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)"
XP_049955729.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049940276.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049945112.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049941170.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049959537.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049937685.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049954865.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049963541.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049938378.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952483.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049953991.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_049943318.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049939306.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049941527.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049942284.1	10	MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;MetaCyc: PWY-5890	"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-10 biosynthesis"
XP_049958526.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940314.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049941445.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049963581.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049951827.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049951510.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049947154.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049964069.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049942024.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049953154.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_049958860.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-399719	"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Interferon gamma signaling";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors"
XP_049959521.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_049948139.1	15	MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-6142	"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049954904.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-975634	"Chylomicron remodeling";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class H Receptors";"VLDL assembly";"LDL clearance";"VLDL clearance";"Chylomicron assembly";"Chylomicron clearance";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport"
XP_049952855.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_049946345.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049961161.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_049939934.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049938761.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_049949121.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049962623.1	18	MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7221;Reactome: R-HSA-5624138;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6	"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of myristoylated proteins to the cilium";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_049958892.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049938157.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049947061.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049954805.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049949315.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049949350.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049958715.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_049961525.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049956836.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049941973.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049945815.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049958861.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049954900.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049959996.1	13	MetaCyc: PWY-5497;MetaCyc: PWY-7909;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5030	"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate polyglutamylation";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III"
XP_049962937.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7102	"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)"
XP_049953053.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_049952818.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049956315.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049958300.1	16	Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-196025;Reactome: R-HSA-164939;Reactome: R-HSA-8856828;Reactome: R-HSA-167590	"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Recycling pathway of L1";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"Formation of annular gap junctions";"Nef mediated downregulation of CD28 cell surface expression";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation"
XP_049950938.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049953177.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
XP_049964852.1	6	MetaCyc: PWY-5497;Reactome: R-HSA-70921;KEGG: 00670+2.1.2.5;KEGG: 00340+2.1.2.5;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030	"Purine nucleobases degradation II (anaerobic)";"Histidine catabolism";"One carbon pool by folate";"Histidine metabolism";"One carbon pool by folate";"L-histidine degradation III"
XP_049957033.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049953876.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"Neutrophil degranulation";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049947118.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Anandamide biosynthesis I"
XP_049941443.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049938595.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049960141.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049961160.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_049956168.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049956991.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049951723.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049957819.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049945882.1	3	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation"
XP_049962327.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049947062.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049950050.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049938707.1	22	MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7053;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-7592;MetaCyc: PWY-6598	"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis"
XP_049954511.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_049949233.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049937407.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049947052.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_049958559.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049952942.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_049960879.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049948663.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_049952266.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049961206.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049955779.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049955940.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049955019.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049944767.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049940199.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049945399.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049962730.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_049952612.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562	"ABC-family proteins mediated transport";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)"
XP_049943712.1	56	Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346	"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis"
XP_049947334.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049955587.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049960814.1	7	Reactome: R-HSA-1660516;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660499	"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane"
XP_049960880.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049960825.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_049963401.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049963441.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation"
XP_049952575.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049960788.1	15	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)"
XP_049955664.1	11	Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_049950932.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049955741.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049959841.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391	"G-protein activation";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Ca2+ pathway";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling"
XP_049951409.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049954240.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053	"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II"
XP_049943998.1	13	KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6969	"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049937502.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049941631.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
YP_010417135.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049943048.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955545.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron assembly";"Chylomicron clearance";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"VLDL assembly";"LDL clearance";"VLDL clearance";"Platelet sensitization by LDL";"Chylomicron remodeling";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling"
XP_049953983.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Synthesis of PC"
XP_049951003.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829	"Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy"
XP_049951929.1	13	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5218920	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"VEGFR2 mediated vascular permeability"
XP_049938451.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_049951957.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049947106.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049957247.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953752.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049963563.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049959944.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049962932.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974	"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Degradation of DVL";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway"
XP_049943573.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049951541.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049937342.1	13	KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18	"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450"
XP_049953736.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049956579.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049957007.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049950668.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049959578.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049941439.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049942253.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049954031.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049943763.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-201688	"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL"
XP_049962668.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_049957907.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049941696.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938	"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)"
XP_049949376.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049945259.1	24	Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"Ca2+ pathway";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_049939182.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049951411.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049961648.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049960286.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049957449.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049959022.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049954012.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725	"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049941050.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049945238.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049963743.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049963273.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5855	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_049964781.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049952173.1	57	Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-75815	"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D"
XP_049955954.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049939745.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049946091.1	15	MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-6886	"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Rubisco shunt";"Purine metabolism";"Glycolysis";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)"
XP_049950479.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049945596.1	12	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-73762;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression"
XP_049954940.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049958806.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_049950344.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049960836.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049942144.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049950521.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049947509.1	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_049950443.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049943286.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049941626.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049960397.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049954522.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_049940428.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049950977.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_049957298.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049964880.1	4	Reactome: R-HSA-917937;Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874	"Iron uptake and transport";"Heme degradation";"Porphyrin and chlorophyll metabolism";"Heme degradation I"
XP_049941049.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049959500.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049937702.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049941759.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049946444.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049954535.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892	"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_049963279.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049960233.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049951505.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_049963803.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049942354.1	12	Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Selenocompound metabolism";"Sulfite oxidation III";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Purine metabolism";"Purine metabolism";"Selenate reduction";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Transport and synthesis of PAPS"
XP_049959302.1	13	KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52	"Other glycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049951718.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049960464.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049938303.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049943962.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_049958518.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049958003.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049950599.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049963226.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049962151.1	26	Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Kinesins";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_049961997.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049942217.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049941387.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962280.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049954612.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049949799.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049962305.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049938762.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049949381.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049952166.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
YP_010417139.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049963216.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049962138.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049941824.1	31	MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6282;Reactome: R-HSA-75105;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-5366;Reactome: R-HSA-163765;MetaCyc: PWY-7388;MetaCyc: PWY-7858	"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Biotin metabolism";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"ChREBP activates metabolic gene expression";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II"
XP_049961012.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049950219.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049951896.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049940062.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049962017.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049963875.1	52	Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-6782210	"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049962281.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049960851.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_049938569.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049946487.1	7	Reactome: R-HSA-1483226;MetaCyc: PWY-6351;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352	"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis"
XP_049939634.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_049954360.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_049940593.1	57	Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_049960754.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049949136.1	7	Reactome: R-HSA-174403;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis"
XP_049963053.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_049962060.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049955289.1	5	MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_049946642.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049959708.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049955220.1	11	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Oxidative Stress Induced Senescence";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049961509.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049943031.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951309.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049954169.1	6	MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049958519.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049946064.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049950372.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_049963588.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049952565.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049958252.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_049959661.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049954432.1	10	MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_049953687.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049963289.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049941811.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049960465.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049941739.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049953452.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049954959.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049963221.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049963110.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049963194.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049957972.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049942008.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13	"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism"
XP_049956797.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049938308.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049941421.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049950305.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049952566.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049951304.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049939854.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049950308.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049951902.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049963975.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049956071.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
XP_049956059.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049938362.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049949654.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049941515.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940475.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049942268.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway"
XP_049962433.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049941492.1	25	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Kinesins";"Cilium Assembly";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins"
XP_049937824.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049954788.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049952689.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049954120.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049952582.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049938585.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049938398.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049951050.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049941187.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049942589.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962546.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049937573.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168276	"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways"
XP_049943723.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049955907.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049960370.1	9	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-446343;Reactome: R-HSA-446353;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Cell-extracellular matrix interactions";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049962902.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049956699.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049938333.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937930.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049956426.1	5	MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_049940101.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049942111.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049941347.1	7	MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049955452.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_049948504.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049959556.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_049960159.1	6	KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane"
XP_049962677.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049942223.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049939379.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049955912.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049952749.1	6	KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780	"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin transport and metabolism"
XP_049953135.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049951965.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049952673.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049941372.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049957792.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049963833.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049952560.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049938152.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049959960.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049951935.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_049956306.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049963115.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049949333.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049949982.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_049959614.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049951897.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049946599.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049937895.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_049954273.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049952524.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049937700.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_049962700.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049963766.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049942592.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049950841.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049963918.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049949598.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049950309.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049964669.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049937365.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049941755.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049963817.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049954482.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950508.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049950058.1	17	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049942909.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049961517.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049959404.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049956700.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Ether lipid metabolism";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Synthesis of PA"
XP_049954566.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049939170.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049941790.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049938232.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049954431.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability"
XP_049947846.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049941763.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes"
XP_049954586.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049954829.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049962446.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049951559.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049941242.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049954768.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049959678.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049938884.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049957369.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_049957102.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_049945686.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049959311.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049941379.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049950262.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049943009.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049950300.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049942174.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_049944800.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049959094.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049938366.1	14	Reactome: R-HSA-70895;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5104;MetaCyc: PWY-5076;MetaCyc: PWY-7767;MetaCyc: PWY-5108;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5101	"Branched-chain amino acid catabolism";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-valine degradation II";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"L-isoleucine biosynthesis II"
XP_049939461.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation"
XP_049940598.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_049958698.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049941055.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049937825.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049960094.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049942567.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Protein ubiquitination"
XP_049963107.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049961465.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049953517.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049955941.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049958923.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049940283.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
XP_049963025.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049959301.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_049959437.1	7	MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2	"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049963288.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049955095.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049948110.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_049939244.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_049954370.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049961522.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049940164.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049961580.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049963680.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049938161.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049959152.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation"
XP_049949123.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_049956626.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049950918.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049939946.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049942219.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049961398.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959361.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049946454.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049958029.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952570.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049937985.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954598.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_049957167.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049958714.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes"
XP_049940541.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049959135.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049964661.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049961211.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_049951041.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs"
XP_049955903.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049951154.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049943762.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Signal transduction by L1";"WNT mediated activation of DVL"
XP_049950448.1	6	KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes"
XP_049959487.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049960518.1	5	MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6	"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_049949369.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049963753.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049941111.1	33	MetaCyc: PWY-1801;MetaCyc: PWY-5082;MetaCyc: PWY-3162;KEGG: 00680+1.1.1.284;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6802;MetaCyc: PWY-5076;MetaCyc: PWY-7111;MetaCyc: PWY-5486;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00592+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00350+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6871;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5480;Reactome: R-HSA-71384;MetaCyc: PWY-6587;MetaCyc: PWY-6342;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-7118;MetaCyc: PWY-6333;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-7798;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-5751	"Formaldehyde oxidation II (glutathione-dependent)";"L-methionine degradation III";"L-tryptophan degradation V (side chain pathway)";"Methane metabolism";"Metabolism of xenobiotics by cytochrome P450";"L-phenylalanine degradation III";"Salidroside biosynthesis";"L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Pyruvate fermentation to ethanol II";"Chloroalkane and chloroalkene degradation";"(S)-propane-1,2-diol degradation";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"L-isoleucine degradation II";"Tyrosine metabolism";"Glycine, serine and threonine metabolism";"3-methylbutanol biosynthesis (engineered)";"Naphthalene degradation";"Pyruvate fermentation to ethanol I";"Ethanol oxidation";"Pyruvate fermentation to ethanol III";"Noradrenaline and adrenaline degradation";"Glycolysis / Gluconeogenesis";"L-valine degradation II";"Chitin degradation to ethanol";"Acetaldehyde biosynthesis I";"Retinol metabolism";"Serotonin degradation";"Protein S-nitrosylation and denitrosylation";"Drug metabolism - cytochrome P450";"Butanol and isobutanol biosynthesis (engineered)";"Phenylethanol biosynthesis"
XP_049951280.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049941153.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049962330.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432722	"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis"
XP_049952029.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_049954823.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049962801.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049963119.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049947371.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950656.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049960731.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049955557.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049952794.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049953650.1	5	KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049953491.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049942479.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049950704.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_049942107.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049964720.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049947036.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049960839.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049954210.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049942540.1	16	Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1250342;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-6811558;Reactome: R-HSA-1251985;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1963640	"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Nuclear signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"GRB2 events in ERBB2 signaling"
XP_049951825.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049953947.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049954548.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082	"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Estrogen-dependent gene expression";"PPARA activates gene expression";"RORA activates gene expression"
XP_049955812.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_049938678.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049950863.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049956468.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049955701.1	5	Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-5668599	"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases"
XP_049960366.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049942528.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049950467.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049962125.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049942226.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049963147.1	5	Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_049959338.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049958830.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049943710.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049950279.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049960026.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049959790.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_049964751.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049958126.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049949806.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_049962705.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049943957.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1"
XP_049956257.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049938159.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049950659.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049956386.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049939291.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091	"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells"
XP_049939223.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049938628.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049939462.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-3821;Reactome: R-HSA-5609977	"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_049963425.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049964882.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049954855.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049946946.1	7	Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049964721.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049962799.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049952126.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049949251.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049963814.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049937341.1	13	KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-2261;Reactome: R-HSA-196836;MetaCyc: PWY-7533	"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis"
XP_049964353.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937278.1	9	KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II"
XP_049939554.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_049954317.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049960081.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049955556.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049937731.1	4	KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583;Reactome: R-HSA-446199;MetaCyc: PWY-6129	"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis"
XP_049937382.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226	"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049950011.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049951901.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049955952.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049949428.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049948542.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049962377.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049959153.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation"
XP_049961808.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049961033.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049955513.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049960903.1	4	Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049956809.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049953872.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049961822.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049954963.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049950844.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049941308.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_049962726.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049962143.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049944766.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049943454.1	9	Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-7039	"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule"
XP_049937919.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049941612.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049964140.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049938617.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049942434.1	5	MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_049956385.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049962079.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049962479.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049962236.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049960824.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_049962268.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049957831.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049959337.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049940752.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049944145.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049960798.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049948107.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049949814.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-212436	"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway"
XP_049964809.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049949356.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049944217.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049962275.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049960481.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049957371.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_049948154.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_049962012.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049941444.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049956830.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_049945236.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049946463.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049944456.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049951004.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049942314.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_049958006.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049962867.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049949986.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_049963847.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049941365.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly"
XP_049961249.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049959893.1	6	KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;MetaCyc: PWY-7980	"Photosynthesis";"Cristae formation";"Oxidative phosphorylation";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis"
XP_049954395.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_049958655.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049959751.1	11	Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation"
XP_049958983.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049954500.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-1442490	"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"Collagen degradation"
XP_049950915.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049937560.1	4	KEGG: 00440+2.6.1.37;MetaCyc: PWY-6832;Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Phosphonate and phosphinate metabolism";"2-aminoethylphosphonate degradation II";"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049942228.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049956060.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049964474.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049951332.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049960929.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049950397.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049953484.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049962314.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049958122.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049953463.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049958447.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049941016.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049952343.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049958617.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049945940.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049949601.1	8	Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049963708.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049949286.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049952402.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_049946181.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049962276.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049937742.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049955703.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049959613.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049948018.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049947231.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049940307.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_049954239.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-5667	"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I"
XP_049957844.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049939986.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis"
XP_049953501.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049964897.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049953268.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049955877.1	3	Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741	"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049951261.1	11	MetaCyc: PWY-7124;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403	"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)"
XP_049949431.1	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes"
XP_049938127.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049959805.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_049948535.1	5	MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4	"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism"
XP_049946305.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_049948419.1	12	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-5250924	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression"
XP_049961142.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049938373.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049947747.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049960154.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049957810.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951214.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049960863.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049940035.1	4	Reactome: R-HSA-9031525;MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-983168	"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049941475.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049962722.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049939298.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049945333.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049937585.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049950618.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049945756.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism"
XP_049959959.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_049951511.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049956049.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_049937858.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049963234.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049948468.1	9	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes"
XP_049949246.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049962296.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049963262.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049951303.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049950684.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049938155.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049950673.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049941743.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049958176.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049941330.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049938613.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049963340.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049949997.1	8	MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-2301;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4	"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis"
XP_049961039.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049938337.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049949514.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049949231.1	10	Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-111457	"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria"
XP_049951211.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049950692.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Dual incision in TC-NER"
XP_049943949.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049953792.1	7	Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258	"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Degradation of DVL"
XP_049961013.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953981.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-8948751	"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of PTEN stability and activity"
XP_049938334.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-6708;KEGG: 00130+2.5.1.39;Reactome: R-HSA-1268020;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5856	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Mitochondrial protein import";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_049944087.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)"
XP_049944216.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049948612.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049948602.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049953764.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049945999.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"One carbon pool by folate"
XP_049946006.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049953998.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418555	"Peptide ligand-binding receptors";"G alpha (s) signalling events"
XP_049944799.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049938548.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049953263.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049955542.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049950857.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049950360.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049951047.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049950719.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_049937306.1	10	Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916	"MPS VII - Sly syndrome";"Neutrophil degranulation";"HS-GAG degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation"
XP_049963037.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Promoter Escape"
XP_049959333.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049957790.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955559.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049939030.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049947825.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049948416.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_049962375.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049955951.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_049950268.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049949342.1	20	Reactome: R-HSA-380972;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;KEGG: 05165+2.7.11.1	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Macroautophagy";"Human papillomavirus infection"
XP_049950839.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049939125.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049957781.1	3	Reactome: R-HSA-5678520;Reactome: R-HSA-193368;Reactome: R-HSA-159418	"Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Recycling of bile acids and salts"
XP_049952820.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946	"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants"
XP_049962480.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049954710.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049961410.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049945766.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049958623.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049939236.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049952110.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049942924.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049943043.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049958943.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049950679.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex"
XP_049937374.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_049958769.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049951895.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049946117.1	2	MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis"
XP_049937378.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_049962671.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049956561.1	12	MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1	"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Purine metabolism";"One carbon pool by folate";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism"
XP_049954182.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049952770.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049956037.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049945398.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049946468.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049960506.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049955500.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_049937785.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049943421.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049961588.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049958337.1	13	MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation"
XP_049962014.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049964079.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_049950367.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049949213.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049963836.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049954578.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049958767.1	2	KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5	"Pentose and glucuronate interconversions";"Fructose and mannose metabolism"
XP_049954245.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049952067.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049952298.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049950321.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049960914.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049951100.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_049962984.1	31	MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-7723;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-5366;Reactome: R-HSA-163765;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-8047;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-6282;Reactome: R-HSA-75105	"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Biotin metabolism";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"ChREBP activates metabolic gene expression";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis"
XP_049961607.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941366.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049949361.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049950802.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049954819.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049957585.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Eukaryotic Translation Termination"
XP_049952247.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_049955996.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049963040.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_049952518.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049950264.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049938050.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_049952764.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049953831.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049962484.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049938386.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049955234.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423	"Chylomicron clearance";"Scavenging by Class F Receptors";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Chylomicron remodeling";"VLDL clearance";"Scavenging by Class H Receptors";"LDL clearance";"VLDL assembly"
XP_049964070.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049949071.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_049949497.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049952857.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941	"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Neutrophil degranulation";"Starch degradation V";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen degradation II"
XP_049962749.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049949156.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049942449.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049961746.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049961609.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049960177.1	20	MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7340	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_049953982.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-201688	"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL"
XP_049951382.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_049953919.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049949407.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049942068.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049941041.1	17	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-8953750;Reactome: R-HSA-176187;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1	"Thermogenesis";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Human cytomegalovirus infection";"mTOR signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Signaling by SCF-KIT";"Transcriptional Regulation by E2F6";"Activation of ATR in response to replication stress";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway"
XP_049954092.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_049944001.1	14	MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5667	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I"
XP_049958445.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_049942190.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049956980.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049947367.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049951683.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049941472.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049964242.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959459.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049960475.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049940138.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049937826.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049951470.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049951506.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling"
XP_049963714.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049951689.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049950526.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049937605.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049940679.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049940012.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049943981.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049940686.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049939740.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_049963010.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_049958087.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049940447.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049953964.1	6	MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17	"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation"
XP_049956361.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049954880.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049952423.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049937425.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049955518.1	9	Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Defective OGG1 Localization";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049938267.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049963125.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049943300.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049937558.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_049942177.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049943761.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243	"Synthesis of PC";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049953074.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049955235.1	19	Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-432142;Reactome: R-HSA-8963901	"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class F Receptors";"Chylomicron assembly";"VLDL clearance";"Scavenging by Class H Receptors";"LDL clearance";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Platelet sensitization by LDL";"Chylomicron remodeling"
XP_049950398.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049962690.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049948582.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049948533.1	5	KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4	"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism"
XP_049963243.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258	"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL"
XP_049956178.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049954570.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049950540.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049956088.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049950346.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049963582.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049959866.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049960603.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049944528.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049937899.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895	"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis"
XP_049951360.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049957875.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049955937.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049940245.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049953904.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_049958534.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049964791.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049950415.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049940530.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_049953985.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049960364.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049938072.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049953048.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049938008.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049961458.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097	"Activation of RAC1";"Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway"
XP_049938852.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_049957268.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049962490.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
XP_049952261.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049954655.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049962664.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049940900.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049938102.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"Neutrophil degranulation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049937958.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation"
XP_049956880.1	3	Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_049955558.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049950657.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049961474.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049950266.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049957962.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049962153.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049947832.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049959612.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049942230.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049941383.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049957368.1	12	Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-1251985	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4"
XP_049946361.1	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)"
XP_049941830.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049956080.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049958510.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049960267.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049951891.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-196299	"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade"
XP_049961448.1	4	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation elongation"
XP_049963246.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049953858.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines"
XP_049951885.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049957146.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-73863	"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination"
XP_049954409.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049948600.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049949476.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049959508.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049963443.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049960650.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049956603.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959210.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049963709.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049961469.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049942215.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex"
XP_049937845.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049947778.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049942169.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_049960822.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049961257.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_049960944.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049963568.1	7	Reactome: R-HSA-9018681;Reactome: R-HSA-9020265;Reactome: R-HSA-9018676;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9018896;Reactome: R-HSA-9023661	"Biosynthesis of protectins";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of E-series 18(R)-resolvins"
XP_049939909.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049956538.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049956390.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049946352.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation"
XP_049951648.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049945933.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation"
XP_049955431.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049959781.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049962434.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049955258.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049947328.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049960358.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049942415.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049960712.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049952807.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049947312.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049956177.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049942676.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049954233.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049943680.1	8	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049958406.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049960489.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049942175.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049941474.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049950789.1	40	Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-72203;Reactome: R-HSA-5578749	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs"
XP_049951972.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049942056.1	15	Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565	"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049945677.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049953953.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049951581.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952	"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions"
XP_049942017.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049960163.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049956507.1	30	Reactome: R-HSA-8939902;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-2644607;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-2122947;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-1170546;Reactome: R-HSA-180534	"Regulation of RUNX2 expression and activity";"Circadian Clock";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH1 Intracellular Domain Regulates Transcription";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Degradation of GLI1 by the proteasome";"Prolactin receptor signaling";"Vpu mediated degradation of CD4"
XP_049946826.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis"
XP_049959536.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049939705.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049941189.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049938420.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_049955964.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049941038.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049961146.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049959441.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049961931.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049948477.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049948566.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049962309.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049941987.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"HCMV Early Events"
XP_049942166.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049941600.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049961960.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_049963812.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049955551.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_049942675.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049941198.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411	"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_049937993.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049953211.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049962613.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049953225.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_049960102.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049958998.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049960065.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049962779.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_049953724.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049958752.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049961404.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156581	"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation"
XP_049956581.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049955126.1	15	Reactome: R-HSA-9652282;Reactome: R-HSA-8863795;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-9665251;Reactome: R-HSA-9665249;Reactome: R-HSA-9665233	"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab"
XP_049939514.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049957034.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1	"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Purine metabolism"
XP_049943724.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049958000.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049944232.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049941735.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049951035.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049952231.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049960108.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049944525.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049938354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049955125.1	15	Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795;Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986	"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2"
XP_049939930.1	13	MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism"
XP_049963494.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959412.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_049961576.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049964355.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952695.1	6	MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12	"Stachyose degradation";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_049964647.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049963949.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_049961070.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049948862.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049956919.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952879.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_049946012.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049955814.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049951048.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049954957.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049938804.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049964036.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049952836.1	4	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism"
XP_049949260.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_049937574.1	6	MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;MetaCyc: PWY-7077;Reactome: R-HSA-446210	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049949429.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049962290.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049943549.1	9	Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049938787.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_049945120.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049941118.1	40	MetaCyc: PWY-7216;MetaCyc: PWY-6883;MetaCyc: PWY-7656;MetaCyc: PWY-7726;MetaCyc: PWY-7779;MetaCyc: PWY-6945;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-6946;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7007;MetaCyc: PWY-5177;MetaCyc: PWY-5136;MetaCyc: PWY-5138;MetaCyc: PWY-5789;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-7654;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7094;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17	"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Spodoptera littoralis pheromone biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl tert-butyl ether degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Benzoate degradation";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Toluene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Tryptophan metabolism";"2-methylpropene degradation";"Methyl ketone biosynthesis (engineered)";"Glutaryl-coa degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aminobenzoate degradation";"Caprolactam degradation";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Benzoyl-coa degradation I (aerobic)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid salvage";"Geraniol degradation";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"beta-Alanine metabolism";"Propanoate metabolism"
XP_049962181.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049940582.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049957144.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049937351.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049942523.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-191859	"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"snRNP Assembly"
XP_049955093.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049951272.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049938011.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-77595;Reactome: R-HSA-191859;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72203;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-72086;Reactome: R-HSA-77588;Reactome: R-HSA-975957;Reactome: R-HSA-159227;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-975956;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167242	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Processing of Intronless Pre-mRNAs";"snRNP Assembly";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"mRNA Capping";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP independent Mature mRNA";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049950714.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049962547.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049950486.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049963285.1	21	MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7224;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7219;MetaCyc: PWY-7184;MetaCyc: PWY-7221	"CMP phosphorylation";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis"
XP_049964267.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049940445.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049962464.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049951950.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049956655.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5578749	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs"
XP_049956675.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049964162.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Neutrophil degranulation";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049947861.1	7	MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2	"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049952254.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-69017	"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6"
XP_049953900.1	5	Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines"
XP_049954611.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049942224.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049951489.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049940474.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049962212.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_049938828.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049952953.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1"
XP_049949919.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049937725.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049948629.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049939092.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049943519.1	30	Reactome: R-HSA-389357;Reactome: R-HSA-392451;Reactome: R-HSA-198693;Reactome: R-HSA-198323;Reactome: R-HSA-199418;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-111447;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-8876198;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-69202;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-8948751;Reactome: R-HSA-5628897;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634638;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-211163;Reactome: R-HSA-1358803;Reactome: R-HSA-9614399;Reactome: R-HSA-6804758;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400	"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"AKT phosphorylates targets in the cytosol";"Negative regulation of the PI3K/AKT network";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"Activation of BAD and translocation to mitochondria";"Human immunodeficiency virus 1 infection";"RUNX2 regulates genes involved in cell migration";"RAB GEFs exchange GTP for GDP on RABs";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"CTLA4 inhibitory signaling";"Cyclin E associated events during G1/S transition";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"Regulation of PTEN stability and activity";"TP53 Regulates Metabolic Genes";"Thermogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of TP53 Degradation";"AKT-mediated inactivation of FOXO1A";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of localization of FOXO transcription factors";"Regulation of TP53 Activity through Acetylation";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049960718.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049939879.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049947816.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276	"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_049952060.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049943171.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049954414.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049963627.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049960319.1	3	MetaCyc: PWY-7761;KEGG: 00760+3.6.1.22;MetaCyc: PWY-5381	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_049953809.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049944527.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049938059.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937949.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_049959456.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049944885.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049960386.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049964899.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490	"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation"
XP_049942171.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049954853.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049952811.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049952419.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167287;Reactome: R-HSA-983168	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049961617.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049946644.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049961807.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049953051.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049963938.1	11	MetaCyc: PWY-7206;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Riboflavin metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism"
XP_049964727.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049958099.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049937947.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049960713.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049956101.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049949125.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049953877.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-2871809	"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"FCERI mediated Ca+2 mobilization"
XP_049956710.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"T cell receptor signaling pathway";"Human cytomegalovirus infection"
XP_049964222.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_049941810.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049951618.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049963559.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049948344.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049947331.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049939600.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049947951.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049937615.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049941565.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049942157.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049952184.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049954603.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049943026.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955380.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049945767.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049964010.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049938023.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310	"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway"
XP_049962447.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049947636.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049956504.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049939251.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049950259.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049946044.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049957952.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049953871.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049937831.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049957684.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049945310.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049953674.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049954858.1	5	KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_049962901.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049956027.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049956807.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049949473.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049962615.1	10	KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-7328	"Galactose metabolism";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_049962776.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_049958334.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049954208.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049953114.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049947574.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962285.1	5	Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_049961385.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049964629.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_049947577.1	5	Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720	"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis"
XP_049950891.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049960013.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin"
XP_049960164.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049962791.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049939766.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049954330.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049938802.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049951410.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049964875.1	10	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_049959482.1	11	MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;Reactome: R-HSA-500753	"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis"
XP_049939645.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049963660.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049960178.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337	"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_049963608.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049956955.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis"
XP_049942019.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049956918.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049960717.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049940443.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049938098.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_049945119.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950805.1	7	KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_049956198.1	7	MetaCyc: PWY-2942;MetaCyc: PWY-5097;Reactome: R-HSA-389661;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941	"L-lysine biosynthesis III";"L-lysine biosynthesis VI";"Glyoxylate metabolism and glycine degradation";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis II"
XP_049955400.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049953264.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049958086.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243	"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049960242.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049956317.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049944390.1	14	KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-1622;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661	"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I";"Photorespiration ";"Cyanoamino acid metabolism";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycine betaine degradation I"
XP_049956711.1	8	KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"T cell receptor signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049963872.1	52	Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-5578749;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-749476;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-5250924;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-5617472	"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049943003.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049941792.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_049957191.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049938679.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049937821.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049954760.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049951088.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_049963283.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049940590.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_049937564.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049942048.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049963928.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049954581.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049948492.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_049943066.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049950879.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049961337.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination"
XP_049959351.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-5142;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-5366;Reactome: R-HSA-163765;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-7663;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6282;Reactome: R-HSA-75105	"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Pederin biosynthesis";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"ChREBP activates metabolic gene expression";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis"
XP_049952902.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049941057.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049954290.1	3	KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049938512.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049950026.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049956628.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049955822.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_049937694.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_049963591.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049938630.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049954272.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049943088.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis"
XP_049961203.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049940034.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049962052.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049941656.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049953362.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049941251.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049956084.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_049958123.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049951549.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049957203.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049952264.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049941536.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049950362.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049964562.1	7	Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134	"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV"
XP_049950015.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049955848.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049958548.1	18	KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7115	"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049956527.1	24	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;Reactome: R-HSA-5674400;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-392451;Reactome: R-HSA-389357;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-1257604	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Human papillomavirus infection";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"RHO GTPases activate PKNs";"Constitutive Signaling by AKT1 E17K in Cancer";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"Activation of AKT2";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"RSK activation";"PIP3 activates AKT signaling"
XP_049938980.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049961027.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049938624.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_049956948.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937404.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_049961579.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049952849.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049945934.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions"
XP_049942073.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049964611.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049951193.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049958355.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049955231.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049957290.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951625.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049946579.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049943969.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_049956608.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_049949648.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049958987.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049961511.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049956889.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049962205.1	12	KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7857	"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis"
XP_049956004.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049959000.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049962596.1	24	Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Kinesins";"Cilium Assembly";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049948035.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049959604.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049962541.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049940585.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049941537.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700	"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_049947083.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049937602.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049959413.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049960673.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049943870.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049938481.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
YP_010417133.1	7	MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;MetaCyc: PWY-3781;MetaCyc: PWY-6692	"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation"
XP_049951036.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049950369.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_049942482.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049963263.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049948620.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049959140.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049940584.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049953710.1	9	MetaCyc: PWY-5757;MetaCyc: PWY-7769;MetaCyc: PWY-6322;KEGG: 00440+4.1.1.82;MetaCyc: PWY-6682;MetaCyc: PWY-7510;MetaCyc: PWY-8067;MetaCyc: PWY-6839;KEGG: 00998+4.1.1.82	"Fosfomycin biosynthesis";"Phosalacine biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Phosphonate and phosphinate metabolism";"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Methylphosphonate biosynthesis";"2-aminoethylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2"
XP_049947843.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049954206.1	11	Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2"
XP_049956425.1	5	MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_049960078.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_049947342.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049952549.1	12	KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"Relaxin signaling pathway";"Human papillomavirus infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway"
XP_049955839.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-110328	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049947623.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049964654.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049962581.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_049950046.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN"
XP_049939292.1	10	Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-983168	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049957830.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-5578749	"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs"
XP_049948664.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049954167.1	6	MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221	"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049962626.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049962067.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049958827.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II"
XP_049956999.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049951973.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049961699.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049960093.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049947262.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-180534	"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4"
XP_049954589.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049963526.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049949005.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049955165.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Neddylation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049962970.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049948115.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049956902.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049958452.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049959862.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049940539.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049950975.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049950906.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049962469.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_049961603.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049956190.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049954821.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049962994.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_049951727.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960862.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049939929.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049954881.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049954228.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121	"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049943136.1	7	KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16	"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_049955633.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049944265.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049959816.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
XP_049960014.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049955634.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049939786.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049961508.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049954886.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049951862.1	4	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049958506.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_049941556.1	14	Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4"
XP_049947465.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_049952193.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049962610.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049957604.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049957469.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049943922.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049942054.1	10	Reactome: R-HSA-166058;Reactome: R-HSA-168188;Reactome: R-HSA-1236974;Reactome: R-HSA-168179;Reactome: R-HSA-5603041;Reactome: R-HSA-5602498;Reactome: R-HSA-9637628;Reactome: R-HSA-1461957;Reactome: R-HSA-6798695;Reactome: R-HSA-5686938	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Toll Like Receptor TLR6:TLR2 Cascade";"ER-Phagosome pathway";"Toll Like Receptor TLR1:TLR2 Cascade";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR2/4)";"Modulation by Mtb of host immune system";"Beta defensins";"Neutrophil degranulation";"Regulation of TLR by endogenous ligand"
XP_049956243.1	8	Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription"
XP_049953344.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049956849.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049955825.1	14	Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598	"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis"
XP_049957603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049953739.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049960878.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049945309.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049963707.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049962993.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_049952806.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049951551.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_049954345.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049956302.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049962513.1	11	MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8	"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism"
XP_049960505.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049939672.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049947338.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049961895.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_049940472.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049944250.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049952640.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049939366.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049938135.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049941760.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049958313.1	11	MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5381;MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00240+3.1.3.5	"UTP and CTP dephosphorylation I";"Purine metabolism";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Pyrimidine metabolism"
XP_049956313.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049939877.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049939660.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049951213.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049951046.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049943231.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049939218.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049953806.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049959051.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049962586.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049959999.1	11	MetaCyc: PWY-6174;MetaCyc: PWY-6859;MetaCyc: PWY-922;MetaCyc: PWY-7102;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-7560;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-5123;MetaCyc: PWY-6383	"Mevalonate pathway II (archaea)";"All-trans-farnesol biosynthesis";"Mevalonate pathway I";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Methylerythritol phosphate pathway II";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_049943015.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049953513.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049937813.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049955135.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049951616.1	11	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-72163	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway"
XP_049961598.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle"
XP_049957566.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049946459.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049954651.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049963452.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049952397.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049953440.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_049937577.1	34	Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-69656	"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049945981.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049956100.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_049950303.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049953847.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_049941340.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049940059.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049950676.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_049947753.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049958736.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049941733.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049954691.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049948589.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids"
XP_049961399.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049958015.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937626.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049941993.1	10	MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559	"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway"
XP_049938125.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049939277.1	5	MetaCyc: PWY-7919;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_049960250.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049949261.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049962948.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049946447.1	16	Reactome: R-HSA-1250196;Reactome: R-HSA-1963640;Reactome: R-HSA-1250347;Reactome: R-HSA-6811558;Reactome: R-HSA-1251985;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642	"SHC1 events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Nuclear signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"Signaling by ERBB4";"PI3K events in ERBB2 signaling"
XP_049951097.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane"
XP_049961361.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049938606.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_049950048.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049961063.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-113501	"DNA replication initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049943166.1	21	Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5357905;Reactome: R-HSA-445989;Reactome: R-HSA-5602636;Reactome: R-HSA-975144;Reactome: R-HSA-5603029;Reactome: R-HSA-1810476;Reactome: R-HSA-168927;Reactome: R-HSA-1236974;Reactome: R-HSA-933543;Reactome: R-HSA-5607764;Reactome: R-HSA-5603027;Reactome: R-HSA-5357956;Reactome: R-HSA-5684264;Reactome: R-HSA-937039;Reactome: R-HSA-202424;Reactome: R-HSA-937041;Reactome: R-HSA-168638;Reactome: R-HSA-1169091;Reactome: R-HSA-933542	"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Regulation of TNFR1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IKBKB deficiency causes SCID";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IkBA variant leads to EDA-ID";"RIP-mediated NFkB activation via ZBP1";"TICAM1, RIP1-mediated IKK complex recruitment";"ER-Phagosome pathway";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"CLEC7A (Dectin-1) signaling";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"TNFR1-induced NFkappaB signaling pathway";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IRAK1 recruits IKK complex";"Downstream TCR signaling";"IKK complex recruitment mediated by RIP1";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells";"TRAF6 mediated NF-kB activation"
XP_049953968.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_049939535.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049953701.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging"
XP_049944227.1	9	Reactome: R-HSA-70263;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1	"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes"
XP_049937627.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049954604.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049956971.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049939224.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049961430.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960115.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049950845.1	30	Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-2564830;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-73863	"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination"
XP_049940167.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049954770.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049947837.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049941851.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049948831.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049963268.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_049956782.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049960817.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710	"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy"
XP_049948839.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049960043.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049947311.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049953905.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_049956043.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049941250.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049958105.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049946187.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049962848.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049946280.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049945685.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049958444.1	6	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_049954082.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049937812.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049952477.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions"
XP_049942500.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049963737.1	3	Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50	"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_049950311.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049963659.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049953950.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling"
XP_049947589.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049959505.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049939942.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955913.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049941688.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_049961271.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049948908.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049960807.1	6	Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling"
XP_049948883.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049959609.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049952945.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049950057.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049959484.1	4	MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_049953811.1	26	Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049946448.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049939669.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453	"Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response"
XP_049959998.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049948936.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049944274.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049939936.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049948621.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049949575.1	5	Reactome: R-HSA-446388;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-416482	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"Rho GTPase cycle";"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events"
XP_049952255.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049951952.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049962896.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049959281.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049948627.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049950818.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049960202.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049953461.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049949430.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049963112.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"G0 and Early G1";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049946007.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049947272.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_049964096.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049943947.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049951336.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049949449.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049953830.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049942926.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049949244.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049937415.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049943029.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049946232.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049940607.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049951282.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049960962.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049959436.1	7	MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539	"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism"
XP_049948665.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049955239.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049952812.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049943181.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110362	"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair"
XP_049942209.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049948441.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049939673.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049955087.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049952867.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049958167.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049937892.1	7	KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484	"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_049960112.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049956795.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049957479.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049963545.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_049964850.1	8	Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5154;MetaCyc: PWY-4983;MetaCyc: PWY-5	"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis"
XP_049937359.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049951678.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049957893.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049942362.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049937510.1	20	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7205;Reactome: R-HSA-380270	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Recruitment of mitotic centrosome proteins and complexes"
XP_049964666.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049942552.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214815	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones"
XP_049954964.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049955867.1	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
XP_049962521.1	11	MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205	"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose"
XP_049949627.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049945095.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1	"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism"
XP_049943564.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049951199.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_049958115.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_049938402.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049957955.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049941988.1	52	Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-749476;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-72203;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-73762	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation"
XP_049938010.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049942798.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049938269.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049955586.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049960285.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049949336.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049938096.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049960975.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049938720.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1	"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism"
XP_049946248.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049952568.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049960315.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049959892.1	52	Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-72203;Reactome: R-HSA-73780	"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Chain Elongation"
XP_049957717.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049954140.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-416476	"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Ca2+ pathway";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events"
XP_049962452.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-5685938	"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)"
XP_049943023.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049957440.1	29	Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_049937675.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_049939253.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049954433.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049951049.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049951092.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049954424.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049963498.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049956701.1	7	MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PG";"Synthesis of PA";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Ether lipid metabolism"
XP_049941917.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049949638.1	18	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7224;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6	"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes"
XP_049954856.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049940218.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_049952401.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049952018.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_049949317.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049937554.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_049939662.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049939466.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049960128.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049961602.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049940888.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049942516.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049938708.1	22	MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592	"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)"
XP_049948689.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049952133.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049953169.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_049940410.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049964733.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049942404.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049958260.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049952571.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049961136.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049946059.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049952131.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049956086.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049963984.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049950885.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049960377.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049952451.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049945645.1	19	Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-3928662;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-114604;Reactome: R-HSA-5626467;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970	"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"EPHB-mediated forward signaling";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"Rho GTPase cycle";"DCC mediated attractive signaling";"GPVI-mediated activation cascade";"RHO GTPases activate IQGAPs";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1"
XP_049945893.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_049939692.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_049959569.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049946465.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049954834.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049960243.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_049960032.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049954047.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_049956259.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049950927.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049945874.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049959528.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049940624.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497	"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"Cilium Assembly";"MHC class II antigen presentation";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049952898.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049945875.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049950836.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_049951201.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049962241.1	5	Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3	"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes"
XP_049952061.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049957775.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049939178.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049959507.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049941594.1	12	KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13	"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methane metabolism"
XP_049945166.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_049954481.1	7	MetaCyc: PWY-7836;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80	"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_049963810.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049951640.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049955908.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049937861.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049946142.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049964695.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049950652.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049960354.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049949371.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049962952.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049959314.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-191859	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly"
XP_049960073.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049942135.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049942877.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049951404.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049943563.1	4	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049960186.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049950109.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049955553.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_049944231.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049963223.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049954884.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049950256.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049959367.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049959808.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049949537.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049962540.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049957984.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049964529.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049955658.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_049959738.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049961132.1	12	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_049940343.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049953205.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-422356	"Ion homeostasis";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Regulation of insulin secretion"
XP_049960472.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049964778.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049957201.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049941436.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049962209.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism"
XP_049938870.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049954078.1	20	MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337	"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_049964468.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049956724.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_049942424.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_049951531.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_049959529.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049952471.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049940287.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_049960503.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049963941.1	11	KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545	"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049960778.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049946423.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_049946357.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049964537.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049941357.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937816.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049961386.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049937780.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049943894.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049942490.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049960084.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049963662.1	17	Reactome: R-HSA-113418;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167287;KEGG: 04660+3.1.3.16	"Formation of the Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"HIV elongation arrest and recovery";"T cell receptor signaling pathway"
XP_049939969.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_049939237.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6	"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism"
XP_049941281.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049940733.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049946486.1	7	MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049954518.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8866652	"Regulation of TNFR1 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_049946346.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_049946555.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049958982.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049941613.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_049949360.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049955671.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049950379.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049939997.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049956407.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049938266.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049952183.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049952238.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049958598.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049958116.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049961456.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import"
XP_049950352.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination"
XP_049953549.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049939802.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049947309.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049939496.1	14	Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049939377.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049947496.1	10	Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6554;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167	"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol"
XP_049949114.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_049956602.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049959139.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_049952766.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049958581.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049961130.1	12	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-5250924;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049957166.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049964668.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049951956.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049956423.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049940305.1	4	KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism"
XP_049955686.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049952914.1	4	Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241	"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import"
XP_049945757.1	6	MetaCyc: PWY-6606;MetaCyc: PWY-7442;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism"
XP_049952613.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049957902.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049964716.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049948015.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049950702.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049960027.1	13	MetaCyc: PWY-8052;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;MetaCyc: PWY-6367;Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system";"DAP12 signaling";"Generation of second messenger molecules";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049939552.1	1	Reactome: R-HSA-193670	"p75NTR negatively regulates cell cycle via SC1"
XP_049964195.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049950643.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049960113.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049958842.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_049959496.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049943106.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049958373.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049942548.1	18	MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"Anandamide biosynthesis I"
XP_049940433.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049943034.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049958394.1	10	MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II"
XP_049941801.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049938176.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049952072.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049944152.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049940976.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049951644.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049946838.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_049948176.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049941438.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049941478.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049959662.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049963504.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_049951492.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_049951132.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049939823.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049949577.1	5	Reactome: R-HSA-194840;Reactome: R-HSA-446388;Reactome: R-HSA-416482;Reactome: R-HSA-8964616;Reactome: R-HSA-193648	"Rho GTPase cycle";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G alpha (12/13) signalling events";"G beta:gamma signalling through CDC42";"NRAGE signals death through JNK"
XP_049949359.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049959370.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049943058.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049963937.1	11	MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism"
XP_049950152.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049941207.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049953644.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049950925.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049963232.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049939724.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049958877.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049948885.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_049950433.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9619483	"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs"
XP_049952918.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049956560.1	12	KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"One carbon pool by folate";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Biotin transport and metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_049938814.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049962496.1	5	MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_049953352.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049957283.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049957094.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553	"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs"
XP_049938552.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation"
XP_049939760.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049941539.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049938666.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049960789.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049963129.1	18	MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643	"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II"
XP_049937913.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_049963495.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049953732.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049953951.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049951167.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049950931.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049964638.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_049940507.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-69166	"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate"
XP_049963940.1	11	MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism"
XP_049960647.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049939937.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049959942.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049941473.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049956056.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049943259.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049958607.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049961759.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-210747	"Regulation of gene expression in beta cells";"Regulation of gene expression in early pancreatic precursor cells"
XP_049950650.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049957128.1	2	KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_049956389.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049948893.1	5	KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305	"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D"
XP_049952350.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049947253.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049943040.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950371.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_049960690.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049960040.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049940997.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049941926.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049948498.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_049957933.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049964655.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049943339.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940470.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049957894.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049964093.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049937307.1	10	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_049964808.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_049960856.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049963113.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049947949.1	9	Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-975634	"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"HS-GAG biosynthesis";"Retinoid metabolism and transport"
XP_049955483.1	8	Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4983;MetaCyc: PWY-5	"Urea cycle";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis"
XP_049951629.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049951195.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049952919.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049958381.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049948531.1	5	MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4	"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Geraniol degradation"
XP_049963512.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049949556.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049937957.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049962606.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049943014.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049959409.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049940555.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049951637.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049962863.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_049943037.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049942347.1	12	KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6683	"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Sulfur metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III"
XP_049948547.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049949729.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_049954536.1	7	MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204	"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_049945758.1	6	KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6606	"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II"
XP_049937614.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049952023.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553	"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs"
XP_049946469.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049937300.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049938522.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049959004.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049959293.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049950335.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049952805.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049941879.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049964425.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049947265.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049939729.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049960135.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7338	"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_049947955.1	29	Reactome: R-HSA-6803207;Reactome: R-HSA-912446;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-69541;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;Reactome: R-HSA-349425;Reactome: R-HSA-5693548;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-6804757;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Meiotic recombination";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Homologous DNA Pairing and Strand Exchange";"Stabilization of p53";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"Autodegradation of the E3 ubiquitin ligase COP1";"Sensing of DNA Double Strand Breaks";"Human papillomavirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Degradation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Methylation";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Thermogenesis";"G2/M DNA damage checkpoint"
XP_049952240.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049951442.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_049950361.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049937917.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-190873	"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation"
XP_049953801.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049939168.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049943552.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111457	"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria"
XP_049952670.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049961454.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763	"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction"
XP_049956061.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049947238.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_049942503.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049942483.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049956191.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049950538.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049958010.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049963724.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049938996.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049943024.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953228.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049961453.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540	"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1"
XP_049939465.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049948937.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049939242.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_049958601.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049937575.1	34	Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-112382	"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex"
XP_049944808.1	3	Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_049960023.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049951291.1	58	Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5689901;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Metalloprotease DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity"
XP_049959870.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049955332.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049953965.1	6	MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17	"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation"
XP_049939126.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_049960451.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049943946.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049959994.1	13	MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3	"Folate transformations I";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Metabolism of folate and pterines";"Folate polyglutamylation";"One carbon pool by folate"
XP_049954121.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049959523.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049944100.1	6	KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Rubisco shunt";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049937649.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049957149.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049940142.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049950475.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049963507.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049941699.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049940429.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049963161.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049945003.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_049949322.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049954887.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049954284.1	2	Reactome: R-HSA-2129379;Reactome: R-HSA-189085	"Molecules associated with elastic fibres";"Digestion of dietary carbohydrate"
XP_049951679.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049950809.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049942526.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049957572.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-7383;MetaCyc: PWY-8072	"D-Alanine metabolism";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization"
XP_049948500.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174154	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin"
XP_049958505.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049942781.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049950670.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_049951900.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049959375.1	6	MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation"
XP_049949536.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049963740.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_049963444.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049959440.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049948598.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049941713.1	4	KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_049946821.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049938545.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049944805.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049946531.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049961575.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049957628.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049956298.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049943547.1	9	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049956273.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049948404.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_049959770.1	11	Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3"
XP_049956957.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049949288.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049963990.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049951208.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049941921.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049952792.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049940693.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049955763.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049952085.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049938220.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049956937.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049962840.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_049951548.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049957249.1	13	MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism"
XP_049940193.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049958697.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049940329.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483	"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1"
XP_049955865.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049954626.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_049937375.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049941518.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049958894.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049955323.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049938319.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049947503.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049959636.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049949995.1	8	Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-2301;MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_049952418.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery"
XP_049954142.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049948873.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049942657.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049957589.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049949165.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049954045.1	12	MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-6936;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7	"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism"
XP_049946450.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049941767.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049953781.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049957660.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049956085.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_049962100.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690	"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"HCMV Early Events"
XP_049958008.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049960669.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049939420.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049963402.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;Reactome: R-HSA-1474151	"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049938524.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049938175.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049954115.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919	"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils"
XP_049958441.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049951933.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049939243.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049957901.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_049939730.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
XP_049961042.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049943420.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049958563.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049941264.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049942176.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049955285.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_049962890.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_049949243.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049952972.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049944981.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049959603.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049948793.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049959771.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049950517.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049960683.1	11	Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801	"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049960979.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049938511.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497	"Attenuation phase";"Estrogen-dependent gene expression";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049946322.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049942138.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_049961503.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049953227.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049947826.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049940606.1	10	Reactome: R-HSA-72731;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-381042;Reactome: R-HSA-156827;Reactome: R-HSA-382556;Reactome: R-HSA-9648895;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Recycling of eIF2:GDP";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"PERK regulates gene expression";"L13a-mediated translational silencing of Ceruloplasmin expression";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049956814.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049948613.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049952700.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_049940566.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049958753.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049954010.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049939438.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_049939926.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6798695	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation"
XP_049949651.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049957669.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049941659.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049943569.1	10	MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855167;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;MetaCyc: PWY-6366;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365;MetaCyc: PWY-6554	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_049949130.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049950376.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-429947;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049951854.1	8	MetaCyc: PWY-6823;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-947581;Reactome: R-HSA-6798695;KEGG: 00790+4.1.99.22;Reactome: R-HSA-3270619	"Molybdenum cofactor biosynthesis";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Molybdenum cofactor biosynthesis";"Neutrophil degranulation";"Folate biosynthesis";"IRF3-mediated induction of type I IFN"
XP_049943045.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049963472.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049960897.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049940628.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049954267.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049952917.1	4	Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9	"Peroxisomal protein import";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism"
XP_049963675.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049963912.1	1	Reactome: R-HSA-1234176	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049960473.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_049945257.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_049960770.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049937762.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_049955401.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049944681.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_049951546.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049938231.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049941585.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049953980.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853	"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes"
XP_049952111.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049955961.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049962723.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_049950211.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049938621.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049954042.1	12	Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-1187;MetaCyc: PWY-601;MetaCyc: PWY-2821;MetaCyc: PWY-6936	"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)"
XP_049959610.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049947853.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220	"Cilium Assembly";"Kinesins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins"
XP_049947185.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049947146.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049952075.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049947560.1	1	Reactome: R-HSA-5673001	"RAF/MAP kinase cascade"
XP_049947315.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049955949.1	4	MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_049952753.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_049944228.1	9	Reactome: R-HSA-196780;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-70263	"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis"
XP_049956290.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049956430.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049942896.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049941458.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049946577.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049956095.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049963961.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049964030.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049964175.1	8	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_049942504.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049956036.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049950483.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049937429.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049938310.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049941800.1	26	Reactome: R-HSA-8866654;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-6804114;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-4615885	"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Dual incision in TC-NER";"SUMOylation of DNA replication proteins"
XP_049947288.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049962449.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973	"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation"
XP_049937565.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049963652.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049963811.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049946467.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049961830.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049958341.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049952885.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-163680	"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"AMPK inhibits chREBP transcriptional activation activity"
XP_049963017.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049953684.1	5	KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049941356.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049953315.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049953744.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049942348.1	12	MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6932	"Sulfate activation for sulfonation";"Purine metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Selenocompound metabolism";"Sulfite oxidation III";"Monobactam biosynthesis";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction"
XP_049960877.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049948413.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_049950380.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049940224.1	8	Reactome: R-HSA-3270619;KEGG: 00790+4.1.99.22;Reactome: R-HSA-6798695;Reactome: R-HSA-947581;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;MetaCyc: PWY-6823	"IRF3-mediated induction of type I IFN";"Folate biosynthesis";"Neutrophil degranulation";"Molybdenum cofactor biosynthesis";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Molybdenum cofactor biosynthesis"
XP_049962124.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049940857.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049961770.1	9	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)"
XP_049941758.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049949715.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049954962.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049941195.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049960056.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049956166.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049942170.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049961223.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049940067.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049954547.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-3214858	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"PPARA activates gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines"
XP_049954675.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049942338.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_049964344.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049962210.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism"
XP_049943042.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962013.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049939632.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049954802.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049941268.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049950928.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049940969.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049956587.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049963049.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_049940550.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_049953671.1	5	MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049963566.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6807505	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes"
XP_049958517.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049947757.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049955838.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends"
XP_049950911.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049956215.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049941388.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960345.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049948880.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_049953681.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_049952848.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049954034.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049963730.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049962675.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049950212.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_049946583.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049952699.1	12	MetaCyc: PWY-7854;MetaCyc: PWY-5744;MetaCyc: PWY-6969;MetaCyc: PWY-7294;MetaCyc: PWY-7295;KEGG: 00720+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-7118;MetaCyc: PWY-6728;KEGG: 00620+2.3.3.9;KEGG: 00660+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"D-xylose degradation IV";"L-arabinose degradation IV";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"Chitin degradation to ethanol";"Methylaspartate cycle";"Pyruvate metabolism";"C5-Branched dibasic acid metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_049954331.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049962605.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_049946312.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049944002.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-5667	"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I"
XP_049954661.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049956249.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912	"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane"
XP_049937305.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049956815.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049961540.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049955510.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049961159.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049939387.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_049942221.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049955625.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_049963019.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049964758.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049952716.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049941298.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049957655.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049953548.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_049943087.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Plasmalogen biosynthesis"
XP_049952005.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049941725.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049964510.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049949341.1	20	Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-166208;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400	"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"mTORC1-mediated signalling";"Relaxin signaling pathway";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"Thermogenesis";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"mTOR signaling pathway";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Macroautophagy";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049963958.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049961338.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049962448.1	11	Reactome: R-HSA-983231;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213	"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs"
XP_049941249.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049939389.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_049956348.1	4	KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557	"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis"
XP_049947724.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049940591.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049963775.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049937272.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049964509.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049962599.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178	"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans"
XP_049958866.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049953846.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049951094.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049942114.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049946953.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049940437.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001	"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade"
XP_049961434.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049938535.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049950416.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049951641.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049961518.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049958398.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152	"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_049956464.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049952262.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049963561.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049963991.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Hedgehog 'on' state"
XP_049961487.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049961280.1	9	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-1362277	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex"
XP_049958287.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049943248.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_049948884.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049943351.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049957629.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950123.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049950507.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049938316.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049951181.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049955790.1	4	MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047	"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol"
XP_049944457.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049959606.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049938857.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049954534.1	5	MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism"
XP_049938816.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049959435.1	7	KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2	"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis"
XP_049955294.1	5	MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-5531	"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_049938239.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049948820.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049960671.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049947852.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049945850.1	4	Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_049950069.1	8	MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-241	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049949635.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049953305.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049961069.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049964078.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049954274.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049946598.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049941718.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049958092.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049954119.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049939762.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049938471.1	5	KEGG: 00240+2.4.2.4;KEGG: 00983+2.4.2.4;MetaCyc: PWY-7181;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine catabolism"
XP_049948476.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049960152.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049940589.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049949427.1	4	KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049942355.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_049964849.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation"
XP_049957188.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049938062.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049962282.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049951737.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion"
XP_049942425.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_049954446.1	12	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483	"Thermogenesis";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Macroautophagy";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs"
XP_049941910.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049951407.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049957797.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049942192.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_049962371.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049952810.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049937323.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049954857.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049951449.1	7	MetaCyc: PWY-6614;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-3841	"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate";"G1/S-Specific Transcription";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)"
XP_049956794.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049937277.1	9	KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533	"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Gliotoxin biosynthesis"
XP_049952599.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049950340.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049964354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049959312.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049948681.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"HS-GAG degradation";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049961440.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049953214.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049950716.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_049959238.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049954041.1	12	MetaCyc: PWY-6842;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801	"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
XP_049949594.1	42	KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6944;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-1361;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-6863;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7007;MetaCyc: PWY-7778;MetaCyc: PWY-6583;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-5138;MetaCyc: PWY-5136;MetaCyc: PWY-7216;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6945;MetaCyc: PWY-7656;MetaCyc: PWY-7726;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17+1.1.1.35	"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Limonene and pinene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Fatty acid salvage";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"beta-Alanine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Caprolactam degradation";"Aminobenzoate degradation";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to hexanol (engineered)";"Toluene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl ketone biosynthesis (engineered)";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"Tryptophan metabolism";"Fatty acid degradation";"Glutaryl-coa degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid beta-oxidation II (plant peroxisome)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Spodoptera littoralis pheromone biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl tert-butyl ether degradation";"Benzoate degradation"
XP_049951187.1	22	MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7728	"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"
XP_049953873.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-373753	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions"
XP_049955597.1	6	Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"ChREBP activates metabolic gene expression"
XP_049952703.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049952529.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049956422.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049939518.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_049953857.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_049941358.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953251.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049961117.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_049937271.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049955669.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049963745.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049952642.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049953076.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049947592.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049940896.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_049940632.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049954590.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049953104.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049963189.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_049958732.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049959899.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083629	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_049951192.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049960156.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane"
XP_049949283.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049950131.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_049941248.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049961234.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049959581.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049942683.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049942318.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049954044.1	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-6309	"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_049962600.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions"
XP_049947337.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049940479.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049948634.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_049939522.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049952944.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049953153.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049950345.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049960126.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049950878.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049953709.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_049950098.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049939882.1	4	Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-3232142	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of ubiquitinylation proteins"
XP_049943824.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049939640.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049962922.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_049941064.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Cilium Assembly";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_049939641.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049950333.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049951570.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049956022.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049957611.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_049937791.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471	"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_049948415.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis"
XP_049962855.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049960234.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049949580.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049956135.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049943970.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_049960253.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049962167.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049954315.1	3	Reactome: R-HSA-202433;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049938709.1	22	MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7592;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis"
XP_049955191.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049952960.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049941037.1	180	Reactome: R-HSA-168638;Reactome: R-HSA-209560;Reactome: R-HSA-977225;Reactome: R-HSA-162588;Reactome: R-HSA-5676590;Reactome: R-HSA-3322077;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-450321;Reactome: R-HSA-9646399;Reactome: R-HSA-9637628;Reactome: R-HSA-937042;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-2173788;Reactome: R-HSA-180585;Reactome: R-HSA-5655862;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-1236382;Reactome: R-HSA-2894862;Reactome: R-HSA-1236974;Reactome: R-HSA-110314;Reactome: R-HSA-174048;Reactome: R-HSA-5696400;Reactome: R-HSA-75815;Reactome: R-HSA-175474;Reactome: R-HSA-6781823;Reactome: R-HSA-5656121;Reactome: R-HSA-2559585;Reactome: R-HSA-8854050;Reactome: R-HSA-917937;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-4641263;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5654727;Reactome: R-HSA-400253;Reactome: R-HSA-174154;Reactome: R-HSA-6804756;Reactome: R-HSA-168927;Reactome: R-HSA-8939902;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-156827;Reactome: R-HSA-2691232;Reactome: R-HSA-9014325;Reactome: R-HSA-2122947;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-975957;Reactome: R-HSA-8852276;Reactome: R-HSA-5654732;Reactome: R-HSA-5205685;Reactome: R-HSA-5357956;Reactome: R-HSA-1799339;Reactome: R-HSA-168928;Reactome: R-HSA-450302;Reactome: R-HSA-5696394;Reactome: R-HSA-8948747;Reactome: R-HSA-3134975;Reactome: R-HSA-975110;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-6804760;Reactome: R-HSA-2173796;Reactome: R-HSA-450408;Reactome: R-HSA-9636383;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5675221;Reactome: R-HSA-69541;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-445989;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-9633012;Reactome: R-HSA-4641257;Reactome: R-HSA-9615710;Reactome: R-HSA-5696397;Reactome: R-HSA-5684264;Reactome: R-HSA-69231;Reactome: R-HSA-2173791;Reactome: R-HSA-901032;Reactome: R-HSA-5607764;Reactome: R-HSA-2979096;Reactome: R-HSA-1358803;Reactome: R-HSA-5689896;Reactome: R-HSA-532668;Reactome: R-HSA-5689603;Reactome: R-HSA-8863795;Reactome: R-HSA-2173789;Reactome: R-HSA-182971;Reactome: R-HSA-936964;Reactome: R-HSA-192823;Reactome: R-HSA-3785653;Reactome: R-HSA-5358346;Reactome: R-HSA-2559580;Reactome: R-HSA-5632684;Reactome: R-HSA-179409;Reactome: R-HSA-5610785;Reactome: R-HSA-937039;Reactome: R-HSA-72706;Reactome: R-HSA-349425;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-1295596;Reactome: R-HSA-211733;Reactome: R-HSA-6791226;Reactome: R-HSA-937072;Reactome: R-HSA-5693565;Reactome: R-HSA-180534;Reactome: R-HSA-6807004;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1253288;Reactome: R-HSA-69601;Reactome: R-HSA-174490;Reactome: R-HSA-6783310;Reactome: R-HSA-9013973;Reactome: R-HSA-5689901;Reactome: R-HSA-156902;Reactome: R-HSA-2871837;Reactome: R-HSA-937041;Reactome: R-HSA-975956;Reactome: R-HSA-9013507;Reactome: R-HSA-72689;Reactome: R-HSA-975163;Reactome: R-HSA-9010553;Reactome: R-HSA-5654726;Reactome: R-HSA-110312;Reactome: R-HSA-5678895;Reactome: R-HSA-5675482;Reactome: R-HSA-5689877;Reactome: R-HSA-8876493;Reactome: R-HSA-2467813;Reactome: R-HSA-936440;Reactome: R-HSA-209543;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-5656169;Reactome: R-HSA-5668541;Reactome: R-HSA-2173795;Reactome: R-HSA-5696395;Reactome: R-HSA-9604323;Reactome: R-HSA-72764;Reactome: R-HSA-2559582;Reactome: R-HSA-8856828;Reactome: R-HSA-5685942;Reactome: R-HSA-68949;Reactome: R-HSA-5693607;Reactome: R-HSA-2672351;Reactome: R-HSA-9613829;Reactome: R-HSA-912631;Reactome: R-HSA-174178;Reactome: R-HSA-9033241;Reactome: R-HSA-201681;Reactome: R-HSA-975144;Reactome: R-HSA-2408557;Reactome: R-HSA-8951664;Reactome: R-HSA-1169408;Reactome: R-HSA-8856825;Reactome: R-HSA-983168;Reactome: R-HSA-205043;Reactome: R-HSA-8849469;Reactome: R-HSA-5357905;Reactome: R-HSA-8866652;Reactome: R-HSA-9020702;Reactome: R-HSA-5654733	"NOD1/2 Signaling Pathway";"NF-kB is activated and signals survival";"Amyloid fiber formation";"Budding and maturation of HIV virion";"NIK-->noncanonical NF-kB signaling";"Glycogen synthesis";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Aggrephagy";"Modulation by Mtb of host immune system";"IRAK2 mediated activation of TAK1 complex";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Downregulation of TGF-beta receptor signaling";"Vif-mediated degradation of APOBEC3G";"Translesion synthesis by POLK";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"ER-Phagosome pathway";"Recognition of DNA damage by PCNA-containing replication complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Dual Incision in GG-NER";"Ubiquitin-dependent degradation of Cyclin D";"Assembly Of The HIV Virion";"Formation of TC-NER Pre-Incision Complex";"Translesion synthesis by POLI";"Oncogene Induced Senescence";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Iron uptake and transport";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of FZD by ubiquitination";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of FGFR2 signaling";"Circadian Clock";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of TP53 Activity through Phosphorylation";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of RUNX2 expression and activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"L13a-mediated translational silencing of Ceruloplasmin expression";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR3 signaling";"Pink/Parkin Mediated Mitophagy";"TNFR1-induced NFkappaB signaling pathway";"SRP-dependent cotranslational protein targeting to membrane";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"activated TAK1 mediates p38 MAPK activation";"DNA Damage Recognition in GG-NER";"Regulation of PTEN localization";"Regulation of innate immune responses to cytosolic DNA";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"Regulation of TP53 Activity through Methylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Prevention of phagosomal-lysosomal fusion";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of MAPK pathway";"Stabilization of p53";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Degradation of AXIN";"Late endosomal microautophagy";"Gap-filling DNA repair synthesis and ligation in GG-NER";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cyclin D associated events in G1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"ER Quality Control Compartment (ERQC)";"CLEC7A (Dectin-1) signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Downregulation of ERBB2:ERBB3 signaling";"Ovarian tumor domain proteases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"UCH proteinases";"Downregulation of ERBB2 signaling";"TGF-beta receptor signaling activates SMADs";"EGFR downregulation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Viral mRNA Translation";"Myoclonic epilepsy of Lafora";"Hedgehog ligand biogenesis";"Oxidative Stress Induced Senescence";"Hedgehog 'on' state";"APC-Cdc20 mediated degradation of Nek2A";"GLI3 is processed to GLI3R by the proteasome";"IRAK1 recruits IKK complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Autodegradation of the E3 ubiquitin ligase COP1";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Spry regulation of FGF signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Vpu mediated degradation of CD4";"Negative regulation of MET activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Downregulation of ERBB4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Membrane binding and targetting of GAG proteins";"Fanconi Anemia Pathway";"TICAM1-dependent activation of IRF3/IRF7";"Metalloprotease DUBs";"Peptide chain elongation";"FCERI mediated NF-kB activation";"IKK complex recruitment mediated by RIP1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Formation of a pool of free 40S subunits";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Regulation of expression of SLITs and ROBOs";"Negative regulation of FGFR1 signaling";"Translesion synthesis by REV1";"Defective CFTR causes cystic fibrosis";"Regulation of necroptotic cell death";"Josephin domain DUBs";"InlA-mediated entry of Listeria monocytogenes into host cells";"Separation of Sister Chromatids";"Negative regulators of DDX58/IFIH1 signaling";"p75NTR recruits signalling complexes";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Termination of translesion DNA synthesis";"TNFR2 non-canonical NF-kB pathway";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER";"Negative regulation of NOTCH4 signaling";"Eukaryotic Translation Termination";"Senescence-Associated Secretory Phenotype (SASP)";"Clathrin-mediated endocytosis";"HDR through Homologous Recombination (HRR)";"Orc1 removal from chromatin";"Processing of DNA double-strand break ends";"Stimuli-sensing channels";"Chaperone Mediated Autophagy";"Regulation of signaling by CBL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Peroxisomal protein import";"TCF dependent signaling in response to WNT";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Selenocysteine synthesis";"Neddylation";"ISG15 antiviral mechanism";"Cargo recognition for clathrin-mediated endocytosis";"Antigen processing: Ubiquitination & Proteasome degradation";"NRIF signals cell death from the nucleus";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of TNFR1 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Interleukin-1 signaling";"Negative regulation of FGFR4 signaling"
XP_049949211.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049937784.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049942422.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_049946466.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049947829.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049937531.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049943658.1	8	MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"ATP biosynthesis";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation"
XP_049957441.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049953881.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381042	"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression"
XP_049962947.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049960815.1	7	KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_049953869.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049941316.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049963746.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049947485.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049964006.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049940495.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049944148.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_049959936.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049939966.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049949220.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049953472.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049938425.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049944976.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_049964725.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049956869.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049964330.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049937828.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049949006.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049937848.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049960414.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049951893.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049937451.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049950341.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049953794.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049962699.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049943004.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049939768.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049951408.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049938623.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436	"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049957282.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049951647.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049960823.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_049940554.1	22	MetaCyc: PWY-621;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5054;MetaCyc: PWY-6981;MetaCyc: PWY-7347;MetaCyc: PWY-5514;MetaCyc: PWY-6142;KEGG: 00500+5.3.1.9;MetaCyc: PWY-3801;Reactome: R-HSA-6798695;Reactome: R-HSA-70171;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-6992;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7238;Reactome: R-HSA-70263;MetaCyc: PWY-5659;Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-622;MetaCyc: PWY-7385	"Sucrose degradation III (sucrose invertase)";"Glycolysis / Gluconeogenesis";"D-sorbitol biosynthesis I";"Chitin biosynthesis";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Neutrophil degranulation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation IV (sucrose phosphorylase)";"1,5-anhydrofructose degradation";"Pentose phosphate pathway";"Sucrose biosynthesis II";"Gluconeogenesis";"GDP-mannose biosynthesis";"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Starch biosynthesis";"1,3-propanediol biosynthesis (engineered)"
XP_049940160.1	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
XP_049939512.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX"
XP_049941898.1	4	KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_049955444.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049953835.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049952112.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049959753.1	11	Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782135	"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual incision in TC-NER"
XP_049942317.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950867.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
XP_049950103.1	18	Reactome: R-HSA-379726;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;KEGG: 00970+6.1.1.1;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557	"Mitochondrial tRNA aminoacylation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Aminoacyl-tRNA biosynthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis"
XP_049954213.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_049938083.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049953689.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049952420.1	16	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-8951664	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Neddylation"
XP_049943871.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049951183.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049952808.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049947842.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
YP_010417137.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049937268.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049945992.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049955595.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049948137.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049951507.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049950444.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049950306.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049963109.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-2173796	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_049955259.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_049954138.1	24	Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-381676	"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Ca2+ pathway";"Glucagon-type ligand receptors";"G-protein activation";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049937363.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049958276.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049953554.1	19	Reactome: R-HSA-6798695;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-163765;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-6969;Reactome: R-HSA-75105	"Neutrophil degranulation";"Methylaspartate cycle";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis"
XP_049952798.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049950022.1	9	Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_049959809.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049950401.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049950216.1	6	MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis"
XP_049942088.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049939478.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_049939541.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_049950825.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049961072.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049954368.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049938550.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049938144.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049957293.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049954057.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049939400.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049961592.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049950862.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049961222.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049963231.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049956524.1	24	Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-389357;Reactome: R-HSA-392451;Reactome: R-HSA-444257;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"RSK activation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_049964741.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049961387.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049964091.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049964862.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049953363.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049938048.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_049957491.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049937637.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_049963813.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049953854.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049956526.1	24	KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;Reactome: R-HSA-165158	"Human papillomavirus infection";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"RSK activation";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"Activation of AKT2"
XP_049953311.1	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Proline catabolism"
XP_049957707.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049951642.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049950446.1	6	KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020	"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import"
XP_049939288.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049945684.1	11	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-5689880	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Ub-specific processing proteases"
XP_049958497.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049949221.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049938551.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049960590.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049950470.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049962746.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049940438.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731	"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_049962938.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7182	"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I"
XP_049963051.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049954599.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049962055.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049937873.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049949325.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049960539.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049961011.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049957256.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049963691.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756;Reactome: R-HSA-5668599	"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases"
XP_049940502.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049955554.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_049954669.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049939181.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049952415.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049958474.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049940631.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049961349.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_049951202.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_049956047.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049950561.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049962312.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960580.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049940014.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049962622.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049949206.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049957617.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049943881.1	16	Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548	"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks"
XP_049964823.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_049964851.1	8	MetaCyc: PWY-4983;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-4984;Reactome: R-HSA-70635	"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Urea cycle"
XP_049946585.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049952714.1	12	KEGG: 00660+4.1.3.25;MetaCyc: PWY-6728;MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-5749;MetaCyc: PWY-7295;MetaCyc: PWY-7854;MetaCyc: PWY-5744;MetaCyc: PWY-6969;MetaCyc: PWY-7294	"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Chitin degradation to ethanol";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"L-arabinose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"D-xylose degradation IV"
XP_049946990.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049954122.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049955675.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"RAF activation";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding"
XP_049938069.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_049952706.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049941258.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049958196.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_049963499.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049947111.1	4	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"DNA methylation"
XP_049960696.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049953213.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049959511.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_049941262.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049959949.1	8	MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268	"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism"
XP_049938148.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049946636.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049950733.1	8	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049959084.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049964477.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049948625.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049952817.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135	"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation"
XP_049952860.1	7	MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-70221	"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation V";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)"
XP_049957774.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_049948857.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049960389.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport"
XP_049960743.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049948669.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_049937423.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049946429.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049953868.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049937487.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049956585.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049942535.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049938527.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049949980.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_049963878.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049958825.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049953005.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049951734.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049951719.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049949574.1	5	Reactome: R-HSA-194840;Reactome: R-HSA-446388;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-8964616	"Rho GTPase cycle";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42"
XP_049946452.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049939710.1	18	MetaCyc: PWY-5690;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-561;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-5392	"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II"
XP_049946586.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049963018.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049951880.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_049937517.1	5	KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22	"Sphingolipid metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism"
XP_049949009.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049959363.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_049960101.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049948912.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049941440.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049957708.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049941550.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937539.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049959294.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049943708.1	28	Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5685938	"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Meiotic recombination";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"HSF1 activation";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)"
XP_049937758.1	4	MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849	"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin III"
XP_049944802.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049955497.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049939603.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049956835.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049937859.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049949749.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4551638	"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins"
XP_049950815.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049941728.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049948349.1	12	MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;Reactome: R-HSA-3322077	"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Galactose metabolism";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Glycogen synthesis"
XP_049961541.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961416.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049942430.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049957075.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049956922.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049951367.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049956862.1	3	MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049962704.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049954171.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049937430.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049940782.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049961368.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination"
XP_049937808.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049938126.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049962046.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049961233.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049958511.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049951243.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049957385.1	6	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation"
XP_049952200.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-2206291;Reactome: R-HSA-2024096	"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation"
XP_049963827.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049963324.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049958937.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049950347.1	6	Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)"
XP_049937599.1	5	MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_049950400.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049958499.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049959897.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_049960471.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049950477.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049951936.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_049962672.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049948575.1	5	Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-7817	"Synthesis of PG";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049942293.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049937911.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049960802.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-532668;Reactome: R-HSA-5678895	"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of RUNX2 expression and activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective CFTR causes cystic fibrosis"
XP_049943491.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049950775.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_049954346.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049950791.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049952984.1	18	MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00640+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-6783984	"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycine, serine and threonine metabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Propanoate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Lysine catabolism";"Glycine degradation"
XP_049948668.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_049947072.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049937786.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-179409	"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A"
XP_049961339.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049939112.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960025.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049954569.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049958781.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049956327.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049944678.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"Translation initiation complex formation"
XP_049952886.1	11	Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1	"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis"
XP_049951198.1	18	Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167158	"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex"
XP_049943764.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695	"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Signal transduction by L1";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation"
XP_049947389.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_049950474.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049962083.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049952484.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7117	"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_049938674.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_049937410.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049941681.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049962758.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_049945828.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798	"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Activation of SMO";"Release of Hh-Np from the secreting cell"
XP_049962584.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049959410.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_049960728.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049958401.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049955584.1	10	Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15	"Synthesis of PA";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism"
XP_049937857.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049960885.1	17	Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Neddylation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049938629.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049961187.1	6	MetaCyc: PWY-922;Reactome: R-HSA-446199;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33	"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis"
XP_049957623.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049942216.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049957542.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation"
XP_049961196.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049943189.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5626467	"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs"
XP_049956683.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-191859	"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"snRNP Assembly"
XP_049960894.1	4	KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049939763.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049941029.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_049942948.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049951446.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049943825.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049943985.1	29	Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-6782135	"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Meiotic recombination";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"Dual incision in TC-NER"
XP_049953832.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049948181.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049940440.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001	"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade"
XP_049937601.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049949011.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049958525.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049960320.1	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
XP_049958502.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049949351.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049954550.1	11	Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108	"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049947906.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049952622.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049962611.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049942210.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049941849.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049949475.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049940529.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_049941701.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049954241.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411	"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_049953694.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging"
XP_049939826.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049959014.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049955596.1	6	Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_049944840.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049937343.1	13	Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7112;MetaCyc: PWY-7533;Reactome: R-HSA-196836	"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism"
XP_049954207.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049940209.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049946449.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049941325.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_049939813.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049944077.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049940435.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049950525.1	11	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167152	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_049951881.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049961581.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049961213.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049957442.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-73863	"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination"
XP_049956793.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049960381.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-3000171;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-2453902;MetaCyc: PWY-5691	"Neutrophil degranulation";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions";"Amyloid fiber formation";"Purine metabolism";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I"
XP_049941030.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049947550.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_049963668.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049958402.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049948569.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049941549.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940275.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049954007.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)"
XP_049937906.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049964879.1	4	Reactome: R-HSA-189483;Reactome: R-HSA-917937;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18	"Heme degradation";"Iron uptake and transport";"Heme degradation I";"Porphyrin and chlorophyll metabolism"
XP_049937544.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049957445.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy"
XP_049949252.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049958524.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961411.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_049952687.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049941896.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049954030.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049963141.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049941257.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049943044.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049937730.1	4	MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;Reactome: R-HSA-4755583	"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_049958905.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775	"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Long-term potentiation";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ion homeostasis"
XP_049954989.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_049938702.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049949652.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049937419.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049961391.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation"
XP_049949467.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049949280.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049958908.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049962182.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049943760.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-8939243	"Synthesis of PC";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049952708.1	12	MetaCyc: PWY-5749;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-6728;KEGG: 00620+2.3.3.9;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7294;MetaCyc: PWY-6969;MetaCyc: PWY-5744;MetaCyc: PWY-7854;MetaCyc: PWY-7295	"Itaconate degradation";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Methylaspartate cycle";"Pyruvate metabolism";"C5-Branched dibasic acid metabolism";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"L-arabinose degradation IV"
XP_049948999.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049954412.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049953224.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_049963759.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-72203	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"mRNA Capping";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA"
XP_049951512.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049964109.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049939631.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049961711.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis"
XP_049953791.1	7	Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400	"Degradation of DVL";"RHO GTPases Activate Formins";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway"
XP_049961238.1	4	MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_049960111.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049941956.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049960661.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination"
XP_049942919.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962467.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381183	"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_049954540.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049941273.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049960685.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_049959933.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049958735.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049949238.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_049951781.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049943342.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049948135.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049944524.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049957490.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049938775.1	6	Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3	"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes"
XP_049962516.1	11	MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-5659;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Fructose and mannose metabolism"
XP_049937910.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049958903.1	6	MetaCyc: PWY-6364;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_049951855.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049961185.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_049961345.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049960151.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049939691.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_049937959.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049950328.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049937503.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049945881.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_049955842.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049955562.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049962905.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049942855.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049954405.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_049951155.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049953969.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_049957000.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_049950996.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049956777.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049941349.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049960982.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049947415.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049957326.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049953970.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049956997.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049957267.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049962288.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049952019.1	6	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049943657.1	3	KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049943566.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049954849.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049940025.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049937878.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
YP_010417138.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049942933.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_049957213.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049949216.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049952239.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049948633.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_049955728.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049958900.1	6	MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_049941727.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379	"Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres"
XP_049941897.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049938544.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049942034.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049963778.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049946067.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049952191.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049954164.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049941754.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049948861.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049951377.1	5	MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine metabolism"
XP_049954759.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049953093.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049951494.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049958624.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049953623.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049949215.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049951281.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049938619.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049959277.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049963347.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049948534.1	5	MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4	"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism"
XP_049956963.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049962044.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807	"T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling"
XP_049943914.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049938713.1	22	MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-6598;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7049	"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)"
XP_049957266.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049937743.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_049957898.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049958999.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049960088.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-532668	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049955590.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049949200.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_049962839.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_049962955.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049941710.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049946470.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049952858.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941	"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II"
XP_049959934.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049962222.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049963741.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049958314.1	11	MetaCyc: PWY-7185;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7821;MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00240+3.1.3.5	"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Pyrimidine metabolism"
XP_049963738.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_049956338.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049956943.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049949157.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049960819.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-9610379	"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"HCMV Late Events"
XP_049937606.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049963270.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049942517.1	6	Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049937607.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049938133.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049939671.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049960662.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_049938722.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049950422.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049964718.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_049937696.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_049955269.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049952880.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049942289.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049949008.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049964067.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_049956952.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049961057.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation"
XP_049951271.1	4	KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642	"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation"
XP_049960246.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049942346.1	12	KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932	"Purine metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Sulfite oxidation III";"Selenocompound metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Selenate reduction"
XP_049961520.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049950816.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049959309.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049941911.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049939921.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049961591.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049940749.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_049953780.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049955866.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis"
XP_049962851.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_049954009.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049947011.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049960715.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049939761.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049958039.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425	"Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049941642.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049961290.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135	"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Dual incision in TC-NER"
XP_049939637.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049946003.1	6	KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_049957336.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-156581	"Ub-specific processing proteases";"Methylation"
XP_049938935.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049963431.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049943432.1	29	Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"Meiotic recombination";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER"
XP_049956778.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049951853.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049941591.1	12	KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13	"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis / Gluconeogenesis"
XP_049950515.1	3	KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001;MetaCyc: PWY-1269	"Lipopolysaccharide biosynthesis";"Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_049941712.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049941936.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049952396.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis"
XP_049960385.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049953741.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049951653.1	11	MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III"
XP_049942943.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049942917.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049962265.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_049951730.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049956563.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049941741.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation"
XP_049951575.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049958090.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049951186.1	22	MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134	"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation"
XP_049950021.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135	"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation"
XP_049953015.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049957967.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049964763.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049945425.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049940293.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049955598.1	6	Reactome: R-HSA-9640463;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"Wax biosynthesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_049954425.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049943990.1	29	Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511	"Translesion synthesis by POLI";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HSF1 activation"
XP_049955788.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049951443.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_049947764.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_049959598.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049937759.1	4	MetaCyc: PWY-7849;MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97	"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism"
XP_049943823.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049960304.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049952797.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049939980.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049954580.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049952079.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049950671.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049946215.1	5	KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532	"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)"
XP_049954795.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049947196.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_049958120.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049954391.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049954489.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049964358.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049963873.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-167160	"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_049947174.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049956780.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049956969.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049962382.1	6	KEGG: 00380+1.14.13.9;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-7765;MetaCyc: PWY-5651;MetaCyc: PWY-7717	"Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_049950488.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049939187.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049956819.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049954068.1	12	MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801	"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Pentose and glucuronate interconversions";"Galactose metabolism";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)"
XP_049958376.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049945239.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049964311.1	6	Reactome: R-HSA-2024096;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916	"HS-GAG degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation"
XP_049962347.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_049963265.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049937318.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049959335.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049961075.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049959894.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049960709.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049950620.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049956381.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379	"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres"
XP_049960811.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049959148.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049939945.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049937401.1	18	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049950953.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5674400	"Macroautophagy";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049952547.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049948887.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_049964187.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049959682.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049962775.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes"
XP_049939675.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049961016.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049950485.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049942497.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049945896.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049946143.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049952983.1	18	Reactome: R-HSA-71403;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00020+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00640+1.8.1.4;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-70895;Reactome: R-HSA-389661;Reactome: R-HSA-204174	"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycine, serine and threonine metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"Glycine degradation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Lysine catabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049955936.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049947548.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049939702.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049950051.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049952257.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049958637.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049939597.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049939908.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_049955756.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049941163.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_049949327.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408	"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism"
XP_049942035.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049949256.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-69166	"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate"
XP_049961666.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049960895.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049956457.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_049942532.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049959326.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049963793.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049961536.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049948590.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-69017	"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6"
XP_049960910.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_049953734.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049940187.1	8	Reactome: R-HSA-73614;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-6556;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5	"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes"
XP_049937732.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049939771.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049960858.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049949099.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049954660.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049943020.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049964018.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049950052.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049954543.1	10	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"RSK activation";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection"
XP_049960949.1	7	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14	"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes"
YP_010417134.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049959927.1	4	Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260	"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049961209.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206302	"HS-GAG degradation";"CS/DS degradation";"MPS I - Hurler syndrome"
XP_049946090.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-5484	"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycolysis";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_049943628.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049961163.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_049958802.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049939542.1	14	KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6606;KEGG: 00983+1.17.3.2;MetaCyc: PWY-5695;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-6607;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5497;KEGG: 00232+1.17.3.2	"Purine metabolism";"Guanosine nucleotides degradation II";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Theophylline degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Caffeine metabolism"
XP_049943847.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
YP_010417136.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049953760.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049958901.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_049943727.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049938858.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049951279.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049942020.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_049953902.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_049953642.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049940051.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_049952631.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049960255.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049949010.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049961745.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049958893.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049963456.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049951609.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049964813.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049960157.1	6	Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66	"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049953489.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_049941123.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049946494.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049961534.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049959510.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_049942072.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049937557.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_049947173.1	18	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism";"Anandamide biosynthesis II"
XP_049956347.1	3	Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117	"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis"
XP_049956314.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049938063.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049952528.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049948214.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049952961.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_049955322.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049957496.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049954066.1	12	KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-7343	"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I"
XP_049948105.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049938158.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049939167.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049953080.1	5	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_049954584.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049944233.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049950126.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049953740.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049950782.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6	"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049956810.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049964121.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049943415.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049955695.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049958608.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049938634.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_049950516.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049958828.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_049959151.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-164378	"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling"
XP_049956848.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049948623.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049943622.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049950322.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049937427.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049942029.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis"
XP_049942481.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049961887.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049939367.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049948882.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049962519.1	11	MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659	"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis"
XP_049951330.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049952630.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049940103.1	17	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049939435.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049938907.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049954165.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049959990.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049937792.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471	"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_049937875.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049950146.1	5	Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-75896;Reactome: R-HSA-9033500	"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins"
XP_049948093.1	25	Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Kinesins";"MHC class II antigen presentation";"Cilium Assembly";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049950463.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049941378.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_049954415.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049946460.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049964709.1	14	Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598	"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis"
XP_049946433.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049941623.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049960924.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049960401.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049954851.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_049964341.1	10	Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_049957022.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_049941243.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049946293.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049941430.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049942014.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049951631.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049947815.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049961421.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049959463.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049942352.1	12	Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278	"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism";"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III"