Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
EFA08873.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB25768.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
EFA00316.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EFA05365.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
KYB26540.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA07975.2	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8	"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
EFA05757.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EFA01657.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EFA06720.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA10612.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EEZ97595.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EFA08353.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
EFA11394.1	11	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
EFA10058.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA08636.2	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
EFA13018.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
EFA05014.1	19	MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-75105;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695	"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation"
EFA06832.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EEZ98249.2	9	MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-7385	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)"
EFA12820.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EFA10678.2	1	Reactome: R-HSA-390696	"Adrenoceptors"
KYB25531.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA00328.1	29	Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
KYB28556.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
KYB26519.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
KYB28995.1	7	MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
EFA04698.2	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
EFA03502.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
KYB26689.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism"
EFA10392.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
EEZ98638.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
EFA12394.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EFA05270.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
EEZ98471.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
EFA01516.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA04221.1	5	Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109	"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Triglyceride biosynthesis"
EFA06737.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
EFA10689.2	4	Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379	"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres"
EFA00380.1	6	KEGG: 00562+2.7.1.150;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.150;MetaCyc: PWY-6352;Reactome: R-HSA-1660517	"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane"
KYB26700.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
KYB29221.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB25441.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
EFA03006.2	8	Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Other types of O-glycan biosynthesis"
KYB25661.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA01641.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
EFA12365.1	1	Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH2"
EFA07588.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EFA06225.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
KYB28312.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
EEZ99590.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA08470.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
KYB27681.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
KYB28357.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EFA09221.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA01147.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
EFA05513.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA00935.2	16	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
EFA06236.2	3	Reactome: R-HSA-532668;Reactome: R-HSA-901032;MetaCyc: PWY-7511	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination"
KYB29538.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
EFA09533.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA03871.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4549349	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
EFA06448.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
EFA10255.2	12	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-6811436	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic"
EFA04235.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EFA08981.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
EFA07540.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA04272.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
EEZ97738.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6	"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism"
EFA05437.1	4	KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6	"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
EFA06336.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA08972.2	16	Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884	"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX"
KYB24980.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA09960.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
EEZ98119.2	5	Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-901042	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle"
EFA05644.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
KYB25072.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
EFA10307.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
KYB24938.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
EEZ99018.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB24625.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
EFA05403.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151	"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
KYB29593.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EFA10308.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EFA06636.1	8	Reactome: R-HSA-191273;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-7391	"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)"
KYB25925.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
EFA11522.2	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
KYB26922.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA03756.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA11284.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EEZ97220.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
KYB26629.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EEZ98564.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EFA02059.2	5	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis"
EFA04908.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
EEZ97821.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA08274.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA10915.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
KYB26516.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA02345.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C"
EFA04563.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA02257.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
EFA01373.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA07645.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EFA07522.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
EFA10361.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
KYB27609.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
EFA02241.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation"
EFA01633.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EFA03957.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ97735.1	5	MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-7279	"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)"
EFA04998.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA01926.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
EFA00425.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage V";"Purine salvage";"Surfactant metabolism"
EFA02829.1	14	MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6969	"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
EFA07539.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
EFA11302.1	19	Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-3000480	"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Chylomicron clearance";"LDL clearance";"LDL remodeling";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors"
EFA08807.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB26640.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
KYB25734.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EFA08343.2	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism"
EFA10119.2	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
EEZ99198.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EEZ99555.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
EFA05916.2	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
EFA09828.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB25553.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670	"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway"
EFA05022.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
KXZ75802.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA11870.2	5	MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
EFA02162.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
KYB26704.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA04455.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA07580.2	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
EEZ99210.2	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
KYB28376.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
EFA00132.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
EFA10972.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
KYB25350.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
KYB27767.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1474228;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Degradation of the extracellular matrix";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EFA03343.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EEZ97680.1	6	KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
KYB28360.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-936837	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases"
EFA11181.1	5	MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism"
KYB26522.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
KYB24975.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
KYB29334.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB25207.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation"
EFA07141.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
KYB25781.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EFA05192.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
KYB26324.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
EFA04496.1	1	Reactome: R-HSA-8949613	"Cristae formation"
KYB27702.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EEZ99480.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6370;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261	"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle"
KYB27096.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EFA07113.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
KYB24940.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
EFA10149.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EFA01439.2	11	Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events"
EFA01675.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
EFA06528.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA11837.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
KYB28285.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
KYB27811.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA11188.2	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
EEZ97675.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
EFA05348.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
EFA02651.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
EFA00209.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
EFA01820.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport"
KYB27725.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
EFA05870.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
KYB29684.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
KYB26065.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA08627.2	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
EFA08240.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
EFA09953.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
EFA06304.1	10	MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7571;MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Butanoate metabolism";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies"
EFA10641.2	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I"
KYB25587.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA03942.2	5	MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
EEZ99888.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
EFA08560.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842	"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II"
EFA02911.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
KYB27843.1	1	Reactome: R-HSA-156588	"Glucuronidation"
KYB28697.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170	"ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions"
EFA10575.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
EFA00433.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA01611.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
KYB25031.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EEZ99271.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
KYB28414.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EEZ99738.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
EFA09821.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
EFA06696.2	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
EFA03630.2	25	Reactome: R-HSA-8877330;Reactome: R-HSA-8940973;Reactome: R-HSA-8941284;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-8939246;Reactome: R-HSA-8939256;Reactome: R-HSA-8941858;Reactome: R-HSA-8935964;Reactome: R-HSA-8949275;Reactome: R-HSA-8939236;Reactome: R-HSA-8941326;Reactome: R-HSA-8941333;Reactome: R-HSA-8941332;Reactome: R-HSA-8951936;Reactome: R-HSA-8939247;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245	"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates chondrocyte maturation";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in WNT signaling";"Regulation of RUNX3 expression and activity";"RUNX1 regulates expression of components of tight junctions";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates bone development";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling"
EFA05646.1	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
EEZ98589.1	1	Reactome: R-HSA-8951664	"Neddylation"
EEZ99635.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
EFA09017.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
EFA07964.1	20	KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724	"Thermogenesis";"Macroautophagy";"mTOR signaling pathway";"Human cytomegalovirus infection";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription"
EEZ99331.1	26	Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-190840	"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
EFA03256.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA03611.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
KYB25916.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA11129.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5	"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes"
EFA10642.1	14	MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
EFA10460.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex"
EFA01338.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA06624.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
EFA03495.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
KYB26853.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
EFA01478.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EEZ99794.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
KYB29555.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA09144.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
KYB29474.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ97690.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA05256.2	6	MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36	"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
EFA03596.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
EFA06999.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
EEZ97196.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
EFA09871.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA03803.1	1	Reactome: R-HSA-8951664	"Neddylation"
EEZ97929.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ99071.2	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
EEZ99233.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-264870	"Nephrin family interactions";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins"
EFA08733.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
EEZ97983.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
EFA02072.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA03682.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
EFA08646.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB25637.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EFA11211.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA06669.1	7	MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Adenine salvage";"Purine metabolism";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
EFA07467.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
KYB28049.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
EFA03362.2	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
KYB26129.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
KYB29331.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ98143.1	27	Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-975957;Reactome: R-HSA-111367;Reactome: R-HSA-77595;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-72203;Reactome: R-HSA-159227;Reactome: R-HSA-167200;Reactome: R-HSA-77588;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-975956;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-112382	"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SLBP independent Processing of Histone Pre-mRNAs";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of the SLBP independent Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of RNA Pol II elongation complex"
EEZ98784.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA02019.1	3	Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EEZ97708.2	6	Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species"
EFA09107.1	12	KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416	"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
EFA08973.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
EFA09226.1	14	MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1	"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes"
EFA08832.2	15	MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40	"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism"
EFA08192.2	5	Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
EFA10466.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
KYB25265.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA08458.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
KYB27219.1	18	MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation"
KYB26217.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA02475.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
EFA03540.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
EFA06650.2	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
KYB28426.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB25508.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
EFA05812.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA00382.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA01443.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
KYB29205.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EFA08997.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ99260.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA06003.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
EFA05480.2	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
KYB26691.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EFA01328.2	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
KYB29698.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EFA00536.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EFA10186.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB26110.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
KYB27252.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
EFA11848.2	1	Reactome: R-HSA-8964038	"LDL clearance"
EFA05560.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
EFA10104.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA08381.1	4	MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism"
EEZ99137.2	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
KYB26615.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ97868.2	27	Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214	"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins"
EFA05853.2	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807	"T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling"
KYB29220.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
KYB27856.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA02215.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ98372.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity"
EFA00320.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA02449.2	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
EFA11590.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692	"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity"
KYB24587.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
EFA07427.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB25840.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA04829.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EFA04205.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EEZ97826.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
EFA11023.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA11131.1	7	KEGG: 00240+2.7.4.14;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
EEZ97344.2	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
EFA11457.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
KYB26216.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB29336.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA09306.2	1	Reactome: R-HSA-8951664	"Neddylation"
EFA07439.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA12204.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
KYB26603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA06873.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
KYB25931.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA02562.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EFA05016.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
KYB27623.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA09578.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
EFA02113.2	7	Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166	"Synthesis of PG";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA"
EFA04640.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
EFA11005.2	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
EEZ97419.2	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
EEZ98942.2	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
EEZ98451.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
KYB26442.1	1	Reactome: R-HSA-3295583	"TRP channels"
EFA05618.2	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
EFA06831.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA02132.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I"
EFA04179.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
EFA07985.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA07410.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897	"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"Macroautophagy";"Thermogenesis";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes"
EFA02618.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EEZ99545.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
EFA03918.2	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
KYB29485.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA05319.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA08080.1	1	Reactome: R-HSA-5676934	"Protein repair"
EEZ98265.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
EFA09480.2	4	Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-983168	"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA02374.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
EFA08767.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
EFA05894.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
EEZ99366.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
EFA03409.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
KYB26192.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
KYB29442.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397	"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
KYB29141.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
KYB29313.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA06874.2	12	MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527	"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Glycogen synthesis";"Glycerolipid metabolism";"Stachyose degradation"
KYB29509.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB26424.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
EFA00552.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA11124.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
EFA00568.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
KYB28316.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA00389.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
EFA00785.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
EFA11928.2	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA08874.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB28984.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
KYB25900.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
EFA04122.1	18	KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1	"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Sulfolactate degradation III";"Tyrosine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II";"Arginine and proline metabolism"
EFA05269.2	6	Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
KYB25455.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
EFA07516.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
KYB29004.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206302;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS I - Hurler syndrome";"CS/DS degradation"
KYB29225.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
EFA05171.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EEZ97564.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408	"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
KYB29371.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis"
EFA08239.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
EEZ98859.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
KYB26720.1	6	MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Porphyrin and chlorophyll metabolism"
KYB26570.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA05938.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
KYB27861.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
EFA08621.1	10	MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2	"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism"
KYB27854.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
EFA06574.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
KYB26568.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA06332.2	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
EFA01867.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
EFA00550.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
EFA10253.2	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
EFA10835.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events"
EFA05486.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
EFA09212.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
KYB25868.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB25520.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
EFA10139.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
EFA00359.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
EFA06198.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9656256;Reactome: R-HSA-9656255	"Cleavage of the damaged purine";"Defective OGG1 Localization";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing";"Defective OGG1 Substrate Binding"
EFA12075.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA02438.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ97420.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)"
KYB27475.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
KYB26594.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
EFA01451.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
KYB25321.1	5	Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154	"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase"
EFA12967.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
EFA05109.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
KYB25457.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168	"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB26468.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"Separation of Sister Chromatids";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
EFA11788.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ99082.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EFA00369.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
EFA05477.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
EFA00146.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
EFA12798.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA00435.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA07751.2	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
EFA11162.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-912631	"MET activates RAP1 and RAC1";"MET receptor recycling";"Downstream signal transduction";"Regulation of signaling by CBL"
EFA01620.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA04106.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
KYB26254.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)"
EEZ98406.2	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
KYB28574.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA04653.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
KYB25237.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
EFA10954.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
EFA10845.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
KYB26219.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA12048.1	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-7836	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis"
EFA08094.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
EFA10741.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA03355.2	5	MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism"
EEZ99856.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA01479.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EFA07458.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
KYB29565.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EEZ99274.1	10	Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091	"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells"
EEZ98882.2	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
EFA04681.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA00753.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
EFA02575.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA02777.2	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
EFA07386.2	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
EFA10595.2	11	MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-6728;MetaCyc: PWY-7268;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42	"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes"
EFA10728.2	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
KYB27799.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA06205.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
EFA03551.1	22	MetaCyc: PWY-6433;MetaCyc: PWY-6958;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-7726;MetaCyc: PWY-5353;MetaCyc: PWY-7053;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-6598	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis"
EEZ98391.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
EEZ97193.2	15	MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901	"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation"
EFA12271.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EFA00769.1	8	Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
EEZ98354.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
KYB29661.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
KYB27959.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
EFA00586.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EFA02095.1	10	KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7187;Reactome: R-HSA-69205;MetaCyc: PWY-7199;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184	"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
EFA06635.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
KYB26171.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism"
EFA03569.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
KYB28841.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
KYB28254.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7177;MetaCyc: PWY-7176	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis"
KYB26713.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"DNA replication initiation";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
EFA02735.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
EFA08585.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
KYB29870.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
KYB26304.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EFA08776.1	7	MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
KYB29374.1	7	MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"UTP and CTP dephosphorylation I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
EEZ97359.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA09573.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
EEZ97847.2	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
EFA07754.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
EFA07023.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
KYB27842.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA05074.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
EFA03919.1	13	KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7187;Reactome: R-HSA-74259;KEGG: 00740+3.6.1.9	"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine catabolism";"Riboflavin metabolism"
KYB25389.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
EFA00166.1	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
EFA00138.1	5	Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181	"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB"
KYB25718.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA11857.1	7	KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;MetaCyc: PWY-5695	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Inosine 5'-phosphate degradation"
EEZ97178.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA11293.1	18	Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
KYB26675.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EEZ98080.1	4	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505	"Cristae formation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
EFA01792.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5381;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-7821;MetaCyc: PWY-6608	"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation III"
EFA05523.2	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
KYB25198.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
KYB29298.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
EFA02261.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
EEZ99433.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA05327.2	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
EFA10424.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA11295.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EEZ98580.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
EFA07920.2	14	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
EEZ99263.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
EFA05534.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA02739.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EFA09532.2	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
KYB25037.1	3	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539;Reactome: R-HSA-156588	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism";"Glucuronidation"
EFA00408.1	5	Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"Vitamin B6 metabolism"
EFA07806.1	3	KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
EFA02866.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
EFA11447.2	33	Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-191859	"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly"
EFA06341.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
EFA07449.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
KYB27107.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA11787.2	29	Reactome: R-HSA-6803207;Reactome: R-HSA-6804760;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-6803204;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693579;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69541;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-349425;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Human cytomegalovirus infection";"Homologous DNA Pairing and Strand Exchange";"mTOR signaling pathway";"Thermogenesis";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Stabilization of p53";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"Autodegradation of the E3 ubiquitin ligase COP1";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation"
KYB28817.1	5	Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
EFA03028.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EFA03095.1	9	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-1362277;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-69017;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
EEZ98854.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ99539.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA07715.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA12953.2	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
EFA04664.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
KYB28983.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
EFA06996.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
KYB26701.1	4	Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
KYB28048.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA13374.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA03814.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110312	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1"
EEZ99099.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EFA07841.1	10	Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"HS-GAG degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
EFA07069.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"CS/DS degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series"
EFA09884.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA11078.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
EFA05796.2	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
KXZ75611.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA05218.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EFA03699.2	4	Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-4420097	"Downstream signal transduction";"Nephrin family interactions";"Activation of RAC1";"VEGFA-VEGFR2 Pathway"
EFA01203.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EFA09011.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EFA03386.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA01481.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
KYB25393.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA03954.2	11	Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670	"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway"
EFA11183.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
KYB27877.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
KYB29184.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
KYB26569.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA02862.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EFA03427.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping"
KYB24596.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
EFA09973.1	11	MetaCyc: PWY-6606;MetaCyc: PWY-5695;Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-6596;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4	"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Purine catabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism"
EFA05468.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
EFA07009.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB27699.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA06749.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA11495.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA02056.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA12050.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
EFA00803.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
EFA06131.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB26993.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EFA05963.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
EFA03253.1	19	Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-418885;Reactome: R-HSA-2029482;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-5627123;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220	"VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"DCC mediated attractive signaling";"Regulation of actin dynamics for phagocytic cup formation";"EGFR downregulation";"GPVI-mediated activation cascade";"Myogenesis";"RHO GTPases activate IQGAPs";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate PAKs";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins"
EFA04469.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
EFA10961.1	3	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
EFA08217.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA11119.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
KYB26426.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA06047.1	7	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription"
EEZ98801.1	18	MetaCyc: PWY-8053;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I"
EFA12941.2	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
EEZ97459.2	3	MetaCyc: PWY-7511;Reactome: R-HSA-6783310;Reactome: R-HSA-983168	"Protein ubiquitination";"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA12570.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
KYB26545.1	57	Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5658442	"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs"
EFA04088.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
EFA06902.2	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA10720.1	11	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes"
EFA01782.2	27	Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5619107	"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
EEZ99030.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
EFA01794.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-3881;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205	"Defective MPI causes MPI-CDG (CDG-1b)";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose"
EFA00286.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
KYB29726.1	5	MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159	"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
EFA05895.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
EFA10944.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
KYB26007.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
KYB28196.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
EFA06060.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA03901.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA00163.1	14	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-2022377;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
EFA10020.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
EFA07499.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EFA00653.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
EFA06537.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EEZ97919.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA07906.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA09055.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA05531.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EEZ99111.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
EEZ98209.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
KYB28936.1	1	Reactome: R-HSA-173599	"Formation of the active cofactor, UDP-glucuronate"
EFA04216.2	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
EFA02211.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs"
EFA06113.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA02474.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA00476.1	9	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol"
EEZ97278.1	4	MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism"
KYB25936.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
EFA02628.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA08214.1	10	Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111459	"Regulation of the apoptosome activity";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage"
KYB26306.1	3	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
EFA05342.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
KYB29312.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
EFA10417.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling"
EEZ98737.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174084	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C"
EFA05201.1	31	MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;Reactome: R-HSA-75105;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-7723;MetaCyc: PWY-7858;MetaCyc: PWYG-321;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-5989;Reactome: R-HSA-9029558	"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Bacterial bioluminescence";"(5Z)-dodecenoate biosynthesis II";"";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
EEZ97729.2	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
EEZ99702.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EEZ98246.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
EFA11249.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB27482.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA03870.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
EFA06614.2	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
EFA04036.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
EFA06072.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB29873.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
KYB28935.1	6	KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22	"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions"
EEZ99834.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EEZ97225.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
EFA02203.1	13	Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes"
EEZ97379.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
EFA02342.2	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
EFA02607.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA01607.2	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
EFA09021.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB26935.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA04901.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300	"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors"
EFA08644.2	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
EFA01725.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA03346.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
KYB27637.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
EFA08990.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
KYB29706.1	19	Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-381426	"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Chylomicron clearance";"LDL clearance";"VLDL assembly";"LDL remodeling";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
KYB28728.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
EFA03109.1	18	MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642	"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Tyrosine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation"
EFA09273.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
EEZ98125.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA10538.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-6784531	"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus"
EFA11548.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EEZ99110.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
EFA04110.1	6	KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
KYB25937.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EFA11489.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
EFA08297.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA08000.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
KYB29659.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA08911.2	56	Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-8939236	"Downstream TCR signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
EEZ99493.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints"
KYB29867.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EFA01115.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
EFA08014.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
EEZ97207.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA11361.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA04852.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
KYB26517.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EFA01834.2	7	MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790	"UMP biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II"
EFA11555.2	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EEZ97926.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB25521.1	10	MetaCyc: PWY-5022;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-4321;Reactome: R-HSA-916853;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19	"4-aminobutanoate degradation V";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"L-glutamate degradation IV";"Degradation of GABA";"4-aminobutanoate degradation I";"Butanoate metabolism";"Propanoate metabolism";"4-aminobutanoate degradation III";"beta-Alanine metabolism"
EFA08273.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA09922.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EFA11880.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
KYB28973.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684	"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Hedgehog 'on' state"
EFA01250.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA05002.2	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
EFA03288.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
KYB29337.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA11012.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport"
KYB27443.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EEZ97316.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
KYB28637.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EFA07173.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
KYB25590.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA01287.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR"
EFA05442.2	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
EFA09381.2	11	Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436	"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic"
EFA11497.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
KYB25818.1	12	Reactome: R-HSA-196780;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2	"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism"
KXZ75822.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA12884.2	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
EFA04752.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
EFA03166.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
KYB29855.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
EFA01213.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
EFA05648.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Unwinding of DNA";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
EEZ97465.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
EFA12113.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ97967.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EFA00147.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA09312.2	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
EEZ98531.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
EFA03098.1	4	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;MetaCyc: PWY-5188	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)"
EFA08992.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
EFA02339.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA07359.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA00473.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
KYB25440.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA06560.1	40	Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation"
KYB27433.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
EEZ99944.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
EFA10560.2	1	Reactome: R-HSA-176974	"Unwinding of DNA"
EEZ97204.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
EEZ98858.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EFA06672.2	11	Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)"
EFA11496.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EFA13414.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB26371.1	1	Reactome: R-HSA-156588	"Glucuronidation"
KYB28779.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378	"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling"
EFA03337.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
EFA01688.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA01882.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA13134.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-174362;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550	"Selenocompound metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Selenate reduction";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Purine metabolism";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
EFA11523.2	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
EFA00434.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA02512.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
EFA03079.2	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
KYB28399.1	1	Reactome: R-HSA-8876725	"Protein methylation"
EFA09970.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits"
EFA03369.2	9	Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928	"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis"
EFA06447.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
KYB27585.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EFA06224.2	10	Reactome: R-HSA-4719360;Reactome: R-HSA-162699;MetaCyc: PWY-7661;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4717374;MetaCyc: PWY-7922	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
EFA07517.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation"
EFA02717.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
EFA03625.2	11	Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation"
KYB26647.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EFA00915.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
KYB25378.1	29	Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-6782135	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER"
EFA09584.2	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
KYB27919.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
EEZ99889.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
KYB25143.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EFA04639.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
KYB29213.1	14	MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
EFA08819.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
KYB28955.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ97331.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB26651.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
EFA03339.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA10712.2	11	Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events"
EFA05125.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EFA07201.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EFA08601.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling"
KYB27927.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
KYB25432.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
KYB26972.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EFA07112.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA08711.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-499943	"tRNA processing in the nucleus";"Interconversion of nucleotide di- and triphosphates"
EFA03831.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
EFA00904.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
EEZ97248.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
EFA01104.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
KYB25636.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EFA11317.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA07303.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"PPARA activates gene expression"
KYB27620.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA10286.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EFA10607.2	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
EFA12933.2	13	MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1	"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Propanoate metabolism";"Ethanol oxidation";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis"
KYB25888.1	3	MetaCyc: PWY-7511;KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Protein ubiquitination";"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA12018.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EFA02110.1	179	Reactome: R-HSA-69017;Reactome: R-HSA-201681;Reactome: R-HSA-5357905;Reactome: R-HSA-8863795;Reactome: R-HSA-2672351;Reactome: R-HSA-2979096;Reactome: R-HSA-69231;Reactome: R-HSA-168928;Reactome: R-HSA-5632684;Reactome: R-HSA-182971;Reactome: R-HSA-75815;Reactome: R-HSA-162588;Reactome: R-HSA-2173796;Reactome: R-HSA-382556;Reactome: R-HSA-450302;Reactome: R-HSA-72764;Reactome: R-HSA-5654732;Reactome: R-HSA-975110;Reactome: R-HSA-6781827;Reactome: R-HSA-2871837;Reactome: R-HSA-6783310;Reactome: R-HSA-5689901;Reactome: R-HSA-975144;Reactome: R-HSA-2691232;Reactome: R-HSA-5362768;Reactome: R-HSA-8856825;Reactome: R-HSA-2173791;Reactome: R-HSA-6781823;Reactome: R-HSA-110320;Reactome: R-HSA-2559582;Reactome: R-HSA-68827;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-5205685;Reactome: R-HSA-72706;Reactome: R-HSA-69541;Reactome: R-HSA-5656169;Reactome: R-HSA-2122947;Reactome: R-HSA-174113;Reactome: R-HSA-3134975;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-8849469;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-2644606;Reactome: R-HSA-5696397;Reactome: R-HSA-8939902;Reactome: R-HSA-6807004;Reactome: R-HSA-5687128;Reactome: R-HSA-937039;Reactome: R-HSA-1253288;Reactome: R-HSA-5693607;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-179409;Reactome: R-HSA-975956;Reactome: R-HSA-532668;Reactome: R-HSA-912631;Reactome: R-HSA-5685942;Reactome: R-HSA-2894862;Reactome: R-HSA-168927;Reactome: R-HSA-5696395;Reactome: R-HSA-936964;Reactome: R-HSA-2559580;Reactome: R-HSA-9613829;Reactome: R-HSA-8875360;Reactome: R-HSA-9604323;Reactome: R-HSA-8948747;Reactome: R-HSA-5610780;Reactome: R-HSA-6804757;Reactome: R-HSA-5610785;Reactome: R-HSA-5675482;Reactome: R-HSA-9033241;Reactome: R-HSA-2173788;Reactome: R-HSA-72689;Reactome: R-HSA-8866654;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-2408557;Reactome: R-HSA-4641263;Reactome: R-HSA-8876493;Reactome: R-HSA-192823;Reactome: R-HSA-168638;Reactome: R-HSA-5654733;Reactome: R-HSA-5693565;Reactome: R-HSA-5658442;Reactome: R-HSA-205043;Reactome: R-HSA-8866652;Reactome: R-HSA-8951664;Reactome: R-HSA-3785653;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-9633012;Reactome: R-HSA-6782210;Reactome: R-HSA-9636383;Reactome: R-HSA-209560;Reactome: R-HSA-5654727;Reactome: R-HSA-5689877;Reactome: R-HSA-6791226;Reactome: R-HSA-211733;Reactome: R-HSA-3322077;Reactome: R-HSA-450408;Reactome: R-HSA-977225;Reactome: R-HSA-110314;Reactome: R-HSA-2559585;Reactome: R-HSA-9013507;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-936440;Reactome: R-HSA-156827;Reactome: R-HSA-5358346;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-901032;Reactome: R-HSA-174178;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-975957;Reactome: R-HSA-937042;Reactome: R-HSA-2173795;Reactome: R-HSA-937041;Reactome: R-HSA-9010553;Reactome: R-HSA-2565942;Reactome: R-HSA-110312;Reactome: R-HSA-174184;Reactome: R-HSA-1799339;Reactome: R-HSA-6804760;Reactome: R-HSA-5696394;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-9013973;Reactome: R-HSA-8948751;Reactome: R-HSA-9646399;Reactome: R-HSA-1236382;Reactome: R-HSA-9615710;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-1169408;Reactome: R-HSA-8854050;Reactome: R-HSA-5684264;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-917937;Reactome: R-HSA-5689896;Reactome: R-HSA-1358803;Reactome: R-HSA-8939236;Reactome: R-HSA-5357956;Reactome: R-HSA-180534;Reactome: R-HSA-3769402;Reactome: R-HSA-9645460;Reactome: R-HSA-2467813;Reactome: R-HSA-975163;Reactome: R-HSA-400253;Reactome: R-HSA-174490;Reactome: R-HSA-5654726;Reactome: R-HSA-5696400;Reactome: R-HSA-2122948;Reactome: R-HSA-445989;Reactome: R-HSA-5675221;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9637628;Reactome: R-HSA-1295596;Reactome: R-HSA-174084;Reactome: R-HSA-937072;Reactome: R-HSA-4608870;Reactome: R-HSA-175474;Reactome: R-HSA-174048;Reactome: R-HSA-156902;Reactome: R-HSA-983168	"CDK-mediated phosphorylation and removal of Cdc6";"TCF dependent signaling in response to WNT";"Regulation of TNFR1 signaling";"Downregulation of ERBB2 signaling";"Stimuli-sensing channels";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Hedgehog 'on' state";"EGFR downregulation";"Ubiquitin-dependent degradation of Cyclin D";"Budding and maturation of HIV virion";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"ABC-family proteins mediated transport";"activated TAK1 mediates p38 MAPK activation";"Eukaryotic Translation Termination";"Negative regulation of FGFR3 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"FCERI mediated NF-kB activation";"Fanconi Anemia Pathway";"Metalloprotease DUBs";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Formation of TC-NER Pre-Incision Complex";"Translesion Synthesis by POLH";"Senescence-Associated Secretory Phenotype (SASP)";"CDT1 association with the CDC6:ORC:origin complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Pink/Parkin Mediated Mitophagy";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Stabilization of p53";"Termination of translesion DNA synthesis";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of innate immune responses to cytosolic DNA";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of RUNX2 expression and activity";"Negative regulation of MET activity";"MAPK6/MAPK4 signaling";"IRAK1 recruits IKK complex";"Downregulation of ERBB4 signaling";"Processing of DNA double-strand break ends";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"APC-Cdc20 mediated degradation of Nek2A";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of signaling by CBL";"HDR through Homologous Recombination (HRR)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TICAM1, RIP1-mediated IKK complex recruitment";"Formation of Incision Complex in GG-NER";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Oxidative Stress Induced Senescence";"Chaperone Mediated Autophagy";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN localization";"Degradation of GLI1 by the proteasome";"Regulation of TP53 Degradation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of necroptotic cell death";"Peroxisomal protein import";"Downregulation of TGF-beta receptor signaling";"Formation of a pool of free 40S subunits";"E3 ubiquitin ligases ubiquitinate target proteins";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Selenocysteine synthesis";"Regulation of FZD by ubiquitination";"InlA-mediated entry of Listeria monocytogenes into host cells";"Viral mRNA Translation";"NOD1/2 Signaling Pathway";"Negative regulation of FGFR4 signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RAS by GAPs";"NRIF signals cell death from the nucleus";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Neddylation";"Myoclonic epilepsy of Lafora";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Prevention of phagosomal-lysosomal fusion";"NF-kB is activated and signals survival";"Negative regulation of FGFR2 signaling";"Josephin domain DUBs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Glycogen synthesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Amyloid fiber formation";"Recognition of DNA damage by PCNA-containing replication complex";"Oncogene Induced Senescence";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Negative regulators of DDX58/IFIH1 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Hedgehog ligand biogenesis";"Translesion synthesis by POLI";"Dual incision in TC-NER";"ER Quality Control Compartment (ERQC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"IRAK2 mediated activation of TAK1 complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IKK complex recruitment mediated by RIP1";"Regulation of expression of SLITs and ROBOs";"Regulation of PLK1 Activity at G2/M Transition";"Translesion synthesis by REV1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of TP53 Activity through Methylation";"DNA Damage Recognition in GG-NER";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of PTEN stability and activity";"Aggrephagy";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Late endosomal microautophagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"ISG15 antiviral mechanism";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Iron uptake and transport";"Ovarian tumor domain proteases";"Downregulation of ERBB2:ERBB3 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR1-induced NFkappaB signaling pathway";"Vpu mediated degradation of CD4";"Deactivation of the beta-catenin transactivating complex";"Alpha-protein kinase 1 signaling pathway";"Separation of Sister Chromatids";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Circadian Clock";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR1 signaling";"Dual Incision in GG-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulation of MAPK pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"G2/M Checkpoints";"Modulation by Mtb of host immune system";"Spry regulation of FGF signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Asymmetric localization of PCP proteins";"Assembly Of The HIV Virion";"APC/C:Cdc20 mediated degradation of Cyclin B";"Peptide chain elongation";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA10591.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
EFA11311.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
EFA10355.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
EFA08227.2	4	KEGG: 00510+3.2.1.113;KEGG: 00513+3.2.1.113;Reactome: R-HSA-901032;MetaCyc: PWY-7919	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"ER Quality Control Compartment (ERQC)";"Protein N-glycosylation processing phase (plants and animals)"
EEZ99630.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
EFA07465.1	13	Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5689877;Reactome: R-HSA-8876725;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5689896;Reactome: R-HSA-8866654;Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511	"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Josephin domain DUBs";"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Ovarian tumor domain proteases";"E3 ubiquitin ligases ubiquitinate target proteins";"ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"HSF1 activation"
EFA00746.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
KYB29172.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997	"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion"
EEZ97433.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB26420.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA10322.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
EFA06119.2	10	MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I"
EFA00688.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EEZ98123.1	6	Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Cysteine and methionine metabolism"
KYB28443.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EFA07329.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
KYB27796.1	4	MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895	"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism"
KYB26069.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ98206.2	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis"
EFA03938.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA06223.2	5	KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pyruvate metabolism"
EEZ97171.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA05962.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
EFA06727.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA02784.1	5	KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
KYB26276.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
EFA11444.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EEZ98001.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
EFA02742.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EFA05007.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB28730.1	4	Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Trna splicing II";"Trna splicing I"
EFA03408.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
KYB25740.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER"
EEZ98852.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
EEZ99511.2	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
KYB26383.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Negative regulation of MAPK pathway"
EFA03421.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB29038.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
EFA08846.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EEZ97706.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
KYB27895.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA06187.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332	"MHC class II antigen presentation";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin"
EFA11272.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EFA05245.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA05471.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
KYB27749.1	5	MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
KYB28433.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
EFA01630.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EFA00883.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
EFA08590.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-6807505	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes"
EFA03809.2	1	Reactome: R-HSA-8951664	"Neddylation"
EFA02961.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA08768.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
EEZ99701.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
EFA10291.2	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
EEZ99804.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EEZ99277.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
KYB25872.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
KYB29064.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
KYB27090.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA04621.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
KYB25960.1	1	Reactome: R-HSA-211981	"Xenobiotics"
KYB26572.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
KYB24712.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA05320.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EFA04568.2	15	Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
EFA03618.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EEZ97375.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
KYB25876.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
KYB27277.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EFA13447.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA06618.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EEZ98408.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;MetaCyc: PWY-6309;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-5651	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
EFA02260.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
EFA11094.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EFA08909.2	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
KYB29308.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
KXZ75834.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
KYB28737.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EEZ97857.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-5620922	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
KXZ75821.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA06622.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
KYB26921.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA11142.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
EEZ99757.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA08612.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
KYB27827.1	7	KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;MetaCyc: PWY-6471;KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;MetaCyc: PWY-6470;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
EFA01562.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
KYB25846.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA06457.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
EFA03542.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
EEZ97944.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
EFA07130.1	3	MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96	"L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis"
EEZ98530.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB29666.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA05276.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA10489.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA08149.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB27187.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-8853884	"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX"
KYB25889.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA06888.2	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
EFA01427.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EEZ97224.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
KYB27571.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
EEZ97989.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-179409	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A"
EFA04308.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA11184.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
EFA09358.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
EFA05559.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EEZ98584.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EFA01004.2	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB25034.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA06006.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
EEZ98591.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EFA11748.1	10	MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;Reactome: R-HSA-69205;MetaCyc: PWY-7199	"Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage"
EFA10179.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA03073.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
EFA04822.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB29735.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ97382.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
EFA02992.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EFA02473.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EFA00809.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
KYB28874.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EFA10172.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA00145.2	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway"
EFA08054.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
EFA04241.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
KYB29370.1	8	KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism"
EFA10722.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
EFA04915.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA12496.1	5	KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-6798695;MetaCyc: PWY-8060;Reactome: R-HSA-71336	"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway"
EFA00694.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA00319.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
EEZ98156.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EEZ99803.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EFA02892.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
KYB27088.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA06592.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EFA07055.2	33	Reactome: R-HSA-167162;Reactome: R-HSA-8939236;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-69656;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-69273;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167158	"RNA Polymerase II HIV Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex"
KYB26622.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression"
KYB25388.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
KYB24961.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA09341.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EFA05817.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
KYB28677.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EFA09424.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EFA09890.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EFA11240.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
KYB28283.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
EFA04459.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
KYB25358.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB26862.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB27794.1	6	KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Chitin derivatives degradation"
KYB27970.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA01139.2	4	KEGG: 00670+2.1.2.10;Reactome: R-HSA-500753;KEGG: 00260+2.1.2.10;Reactome: R-HSA-73621	"One carbon pool by folate";"Pyrimidine biosynthesis";"Glycine, serine and threonine metabolism";"Pyrimidine catabolism"
EEZ99924.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
KYB25428.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
KYB28367.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
EFA04527.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
EEZ97381.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ98766.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EEZ97505.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB28439.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
EFA06414.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB28438.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
EFA02592.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA01706.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EFA10743.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
KYB27439.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
EFA10422.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
EFA06307.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
KYB25334.1	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;MetaCyc: PWY-7511;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Protein ubiquitination";"mRNA Splicing - Major Pathway"
EFA10463.1	3	Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
KYB28198.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EFA09095.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288	"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1"
EFA10726.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EFA05307.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EFA06770.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EFA08936.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
KYB27442.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EFA04965.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA10196.1	4	KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
EFA10583.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA07971.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
KYB27386.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA01731.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
EFA08151.1	42	KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6883;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7656;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6944;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7216;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00592+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-7401;MetaCyc: PWY-1361;MetaCyc: PWY-5138;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863	"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Benzoate degradation";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Lysine degradation";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Glutaryl-coa degradation";"Fatty acid degradation";"2-methylpropene degradation";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Spodoptera littoralis pheromone biosynthesis";"beta-Alanine metabolism";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Androstenedione degradation";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Limonene and pinene degradation";"Methyl tert-butyl ether degradation";"alpha-Linolenic acid metabolism";"Phenylalanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Aminobenzoate degradation";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)"
EFA09428.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB26900.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201	"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis"
EFA02248.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
EEZ98189.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EEZ99668.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events"
EEZ97351.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)"
EFA12491.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA05094.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
EFA01349.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
EFA02439.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB26348.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
EFA01025.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
EFA04079.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA03859.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
EFA11215.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
EFA11738.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
KYB26858.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA02026.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
EFA01091.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EFA04447.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
EFA10911.2	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
EEZ97977.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
KYB28628.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
EFA04708.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
EFA02518.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
KYB25660.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA07053.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
KYB28639.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EFA00018.1	30	Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-2564830;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-674695	"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events"
EEZ97760.2	7	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)"
EFA12135.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EFA02872.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
EFA12938.2	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
EFA03903.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
KYB29015.1	1	MetaCyc: PWY-6938	"NADH repair"
KYB27182.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EEZ99572.2	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
EFA09999.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA03341.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5658442	"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs"
EFA07621.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
KYB29367.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
EEZ98452.1	5	MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
EFA06923.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
KYB27114.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EFA05322.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EFA05564.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
EFA05745.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EFA10858.2	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
KYB28200.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EFA07181.2	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
EFA01515.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA10201.2	16	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EFA08854.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
EFA09929.2	6	KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle"
KYB27274.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA07309.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA05967.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ98702.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-2559586	"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence"
EEZ97798.2	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
EFA03570.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA09314.2	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
KYB29062.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
KYB29866.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EFA04054.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4641257	"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN"
KYB27481.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EEZ98454.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
KYB25616.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
EFA10819.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
KYB26826.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex"
KYB28494.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
EFA09191.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-9615017	"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
EFA04932.1	12	KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13	"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway"
EFA06334.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA09870.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EFA04885.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
KYB26649.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
EFA05234.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
KYB28979.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA05502.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
EFA01351.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB25099.1	6	Reactome: R-HSA-532668;MetaCyc: PWY-7919;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-2564830;Reactome: R-HSA-4793954	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Cytosolic iron-sulfur cluster assembly";"Defective MOGS causes MOGS-CDG (CDG-2b)"
EEZ97803.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
EEZ98670.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EFA03939.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA11584.2	11	Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-202733	"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall"
EFA10268.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation"
KYB28201.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA03629.2	11	Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-432040	"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins"
EFA07489.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA01864.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA08050.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
EFA09750.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
EFA07817.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
KYB28824.1	1	Reactome: R-HSA-8876725	"Protein methylation"
KYB29291.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
EFA08980.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB26050.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB26314.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EFA01765.1	19	Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-3214858;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RMTs methylate histone arginines";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
EEZ98806.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
KYB28918.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
KYB28696.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083	"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions"
EFA11360.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane"
EFA05436.2	17	Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;MetaCyc: PWY-4381;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780	"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Jadomycin biosynthesis";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Biotin transport and metabolism"
EFA02996.1	5	KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33	"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis"
EFA05359.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA06576.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EFA04974.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
EFA01173.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
KYB29049.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
EFA00824.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA08544.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA04049.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EFA09827.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
EEZ97863.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EEZ99726.1	18	MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-7226	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I"
EFA08701.2	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
KYB27812.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
KYB27179.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
EEZ97602.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
KYB27220.1	18	KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416	"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)"
EFA09067.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-1799339	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane"
EEZ99766.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
KYB26355.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
EFA08682.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
KYB27195.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
EFA07677.2	7	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
EFA03251.1	9	KEGG: 00400+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00130+2.6.1.5	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis"
EFA05105.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8939902	"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity"
KYB27644.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
EFA03645.2	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
EEZ97639.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442	"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs"
EFA00642.2	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EFA10581.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EEZ98187.1	8	Reactome: R-HSA-6791462;Reactome: R-HSA-163754;Reactome: R-HSA-8950505;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-6791055;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336	"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Pentose phosphate pathway"
EFA09947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB29717.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EFA06957.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EFA06856.2	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase"
KYB25257.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
EFA05264.2	6	MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
EFA07221.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
EFA11727.2	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
EFA06431.1	3	Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206	"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha"
EFA03025.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
EFA08779.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
EEZ98937.1	5	MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage"
KYB29624.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-159227	"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA"
EFA03225.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EFA09966.2	1	Reactome: R-HSA-8951664	"Neddylation"
KYB25236.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
EEZ99162.2	11	Reactome: R-HSA-1834949;Reactome: R-HSA-8866654;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Cytosolic sensors of pathogen-associated DNA";"E3 ubiquitin ligases ubiquitinate target proteins";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
KYB27157.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
EFA07642.2	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
EFA04760.2	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
EFA00133.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
EFA05431.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
KYB28387.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA10545.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA12962.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB25229.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I"
EFA04620.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
EFA08139.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
EFA10137.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA11369.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
KYB28994.1	7	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
EFA02571.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
EEZ98703.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EEZ97198.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EEZ99706.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
KYB25372.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA09154.2	5	Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090	"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Collagen degradation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures"
KYB29416.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA09848.2	10	KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04150+2.7.1.153	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"mTOR signaling pathway"
EFA05568.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA10816.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EFA01155.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA05073.1	42	MetaCyc: PWY-6945;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-6883;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7779;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00360+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-5109;MetaCyc: PWY-6944;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7606;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-1361;MetaCyc: PWY-5138;MetaCyc: PWY-7401;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35	"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Propanoate metabolism";"Benzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Lysine degradation";"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid degradation";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"2-methylpropene degradation";"Fatty acid degradation";"Glutaryl-coa degradation";"Methyl tert-butyl ether degradation";"Limonene and pinene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Phenylalanine metabolism";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Fatty acid salvage";"Fermentation to 2-methylbutanoate";"Androstenedione degradation";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Caprolactam degradation"
KYB28159.1	6	Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway"
KYB28293.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
EEZ98644.1	7	MetaCyc: PWY-6385;Reactome: R-HSA-5633231;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470	"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
EFA04773.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
EEZ97516.1	8	MetaCyc: PWY-5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-4983;Reactome: R-HSA-70635	"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle"
EFA11359.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
KYB28309.1	2	Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2	"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway"
EFA11773.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EFA05194.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EEZ99075.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EEZ99704.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
EFA07809.2	10	MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"L-histidine degradation III";"Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)"
KYB27979.1	9	Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
KYB29402.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
EFA13288.2	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
EEZ97886.2	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation"
EFA02619.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
EFA10060.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EEZ97275.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA07860.2	12	KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4	"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism"
EFA08121.1	6	KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
EFA11371.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EEZ98528.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
KYB27790.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
EFA10425.2	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
EFA06899.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB25057.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
EFA02346.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
EFA03420.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA06728.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
KYB26672.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA04581.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
EFA05305.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EFA08161.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EEZ98588.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EFA04754.2	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
KYB27741.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
KYB25213.1	10	MetaCyc: PWY-6372;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
EFA09425.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7338;MetaCyc: PWY-7288	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
KYB26664.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
EFA04151.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EFA03068.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
EFA03876.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
KYB27852.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
EFA02659.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
EFA01958.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
EFA05490.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis"
EEZ99138.2	3	KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
EEZ98876.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
EFA00847.2	7	KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
EEZ98450.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
KYB28308.1	2	Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2	"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway"
KYB29271.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-5619107	"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
EFA11536.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EEZ99554.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
KYB26507.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
EFA07541.2	6	Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
EFA11398.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
KYB27910.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
KYB26614.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA05226.1	40	Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-76042;Reactome: R-HSA-6803529	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing"
KYB29167.1	6	MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-7356	"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)"
EEZ97241.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EEZ97891.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-983189	"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Kinesins"
EFA07160.1	13	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-6728	"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle"
EFA04486.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
EFA03148.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-5368286;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis"
EFA02143.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA04692.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
EFA05255.1	1	Reactome: R-HSA-446193	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
KYB29042.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
EFA00846.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
EFA03430.2	18	MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC"
EEZ98122.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
KYB26172.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle"
EFA08462.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
KYB27097.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA03752.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036	"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
EFA12932.2	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
EFA10126.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA06534.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation"
KYB24612.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA01628.1	8	KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-6791461;Reactome: R-HSA-5659996;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Rubisco shunt";"RPIA deficiency: failed conversion of RU5P to R5P";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
EFA05994.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
EEZ97230.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression"
KYB26936.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB27319.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Golgi Cisternae Pericentriolar Stack Reorganization";"Ca2+ pathway";"cGMP effects"
EFA03261.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA09146.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
KYB27572.1	4	Reactome: R-HSA-9609523;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
EFA06064.2	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
EFA10928.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA04046.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EEZ98465.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
EFA05714.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613	"Oxidative phosphorylation";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation"
EFA12926.2	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
EFA01125.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA07459.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EEZ97297.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
EFA07822.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA11668.2	8	MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5154;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5	"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Canavanine biosynthesis"
EEZ97189.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B"
EEZ99471.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EFA06707.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
KYB24942.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA07520.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA04185.1	4	Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
EFA00490.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
KYB27787.1	9	KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263	"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis"
KYB28197.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EFA08890.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA04705.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA07188.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EEZ98236.2	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
KYB27151.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
KYB27132.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production"
KYB24960.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA06463.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
KYB27271.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-8853884	"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX"
KYB25196.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
EFA05441.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA04019.2	1	Reactome: R-HSA-8949613	"Cristae formation"
KYB26733.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
KYB26273.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
EFA07659.2	56	Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling"
EFA04470.1	12	Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-73762	"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Notch-HLH transcription pathway";"RNA Polymerase I Transcription Initiation"
KYB26462.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EFA04489.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EFA05958.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EEZ97932.2	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
KYB27348.1	10	Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111463	"Respiratory electron transport";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs"
EFA05415.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
EFA02044.2	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
EFA12381.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
KYB25022.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
EFA04609.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
KYB25413.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
EFA05530.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
KYB26317.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EFA11062.1	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
EEZ98343.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
KYB27240.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
EFA02701.2	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
EFA11053.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EEZ97603.1	5	Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"mTORC1-mediated signalling";"HSF1-dependent transactivation";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
EFA12825.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EFA04100.2	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
EFA08517.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis IV (plant cytosol)"
EFA10173.2	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
KYB27757.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788	"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling"
EFA11223.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
KYB27557.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-8939236	"Downstream TCR signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
EFA10313.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
EFA02043.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
EFA11170.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EFA03802.2	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
EEZ97653.2	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
EFA04121.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ99144.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
EEZ99907.2	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
KYB27169.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-1268020	"Complex I biogenesis";"Mitochondrial protein import"
EEZ98379.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EEZ98936.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism"
KYB26694.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
KYB28559.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
EFA03311.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EFA06695.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
EFA11086.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
EFA08703.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
EFA06330.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
KYB26367.1	14	KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-75109;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483191	"Ether lipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"Synthesis of PE";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Synthesis of PC"
EFA07805.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EEZ98060.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
EEZ99829.2	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
EFA04761.2	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
EFA09710.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
EFA13216.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
EFA08071.1	6	MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
EFA00475.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
KYB29101.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-7117	"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
EEZ97323.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
EFA08261.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EFA00843.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
EFA03646.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA04256.2	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
EFA03277.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
KYB25474.1	1	Reactome: R-HSA-156588	"Glucuronidation"
KYB26008.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
EFA11105.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
KYB29037.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6804756	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation"
EFA03061.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA10257.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA03479.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
EFA07655.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
EFA10478.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB29263.1	10	Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"RSK activation";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Recycling pathway of L1";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
EEZ99586.2	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
EFA09153.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490	"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation"
EFA12917.2	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
EFA03584.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-5619107	"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
EEZ98979.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB28879.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
EFA12023.2	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
KYB26880.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
KYB25566.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA09796.1	14	MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
KYB28537.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
KYB25999.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
EEZ97575.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin"
KYB28735.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
KYB25047.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
EFA06546.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EFA07481.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA02476.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport"
EFA09668.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
EFA06741.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling"
EEZ98063.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
EEZ97412.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EFA00136.2	3	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
EFA05099.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
EFA11413.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA10249.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
EEZ98144.2	27	Reactome: R-HSA-73856;Reactome: R-HSA-167158;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-77588;Reactome: R-HSA-167200;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-72203;Reactome: R-HSA-191859;Reactome: R-HSA-975956;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-159236;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-975957;Reactome: R-HSA-111367;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"RNA Polymerase II Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Processing of Capped Intron-Containing Pre-mRNA";"snRNP Assembly";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SLBP independent Processing of Histone Pre-mRNAs";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
EFA01001.1	17	MetaCyc: PWY-5695;MetaCyc: PWY-5532;MetaCyc: PWY-6627;MetaCyc: PWY-6611;MetaCyc: PWY-6644;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-6608;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1	"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Guanine and guanosine salvage";"Purine metabolism";"Pyrimidine metabolism";"Purine catabolism";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II"
EEZ99070.2	24	Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Recycling pathway of L1";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs"
KYB24697.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
KYB28867.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
KYB26872.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA07012.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
EFA00063.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
KYB29653.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA09197.2	14	Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944	"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2"
EFA03279.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
EFA07486.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA02422.2	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
KYB27246.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
EFA02499.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
KYB24967.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EFA10381.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
EFA06125.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ99810.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA05391.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
KYB28837.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
EFA09781.1	16	Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665	"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Gap junction degradation";"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"LDL clearance";"EPH-ephrin mediated repulsion of cells"
EFA05036.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
KYB28573.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295	"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism";"MHC class II antigen presentation"
EFA04432.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA11126.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EFA03247.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
EFA09638.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA02494.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA"
EFA03478.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
EFA00965.2	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
KYB27152.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
KYB25453.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5080;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs"
KYB24563.1	42	Reactome: R-HSA-2559586;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-73728;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-427359	"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Meiotic recombination";"Transcriptional regulation by small RNAs";"HDACs deacetylate histones";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA methylation";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Meiotic synapsis";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Opening";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression"
EFA01192.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
KYB27845.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
EFA02258.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
EFA01258.2	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
EFA07762.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
EFA00805.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"MASTL Facilitates Mitotic Progression";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
KYB25489.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EFA10671.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA00996.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
EFA07527.2	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
EFA05252.2	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
KYB25045.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
EFA05193.2	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EFA10430.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
KYB28368.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
EFA03550.1	32	Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-168325	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis"
EEZ97210.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ99549.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
KYB28978.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29383.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
KYB26338.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EFA02176.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
EFA01375.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
EEZ98728.1	18	Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-1799339	"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane"
EFA08519.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EFA06722.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA10667.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA03187.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
EFA04808.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA05083.2	18	Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409	"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
EFA01612.2	1	Reactome: R-HSA-191859	"snRNP Assembly"
EFA07264.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA09822.2	24	Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-380320	"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Separation of Sister Chromatids";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes"
KYB25431.1	4	MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism"
EFA13640.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
KYB26730.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA07437.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EEZ99936.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29382.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
EEZ97809.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
EFA08812.2	14	Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135	"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER"
EFA07519.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB27923.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones"
EFA07320.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
EFA05000.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
EFA08288.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA01370.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EFA06705.2	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism"
EFA04844.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EFA06497.2	1	Reactome: R-HSA-156588	"Glucuronidation"
KYB28883.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
KYB24969.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EFA13516.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
KYB25451.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA11425.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423	"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"LDL clearance";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"LDL remodeling";"VLDL assembly"
EFA05481.2	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
KXZ75610.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA11222.2	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
EFA09033.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
EFA04529.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA06541.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EEZ98849.2	15	Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176409	"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins"
KYB25356.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB27402.1	13	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;Reactome: R-HSA-4420097	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"VEGFA-VEGFR2 Pathway"
EFA05047.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EEZ98316.2	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA06084.2	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
EFA03533.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EFA03160.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA06167.2	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
KYB29720.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EFA07840.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB26337.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EFA05213.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
EFA11132.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB28647.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA08228.2	10	MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;Reactome: R-HSA-70171	"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis"
EFA04777.2	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EFA04039.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EFA02057.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
EFA05242.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB25968.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
KYB25336.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
KYB28033.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA06382.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
KYB26140.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA01773.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA05479.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
KYB28377.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
EFA03278.1	3	KEGG: 00250+1.4.1.1;Reactome: R-HSA-71403;KEGG: 00430+1.4.1.1	"Alanine, aspartate and glutamate metabolism";"Citric acid cycle (TCA cycle)";"Taurine and hypotaurine metabolism"
KYB28667.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB29142.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
KYB27531.1	4	KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation"
EEZ97219.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
EFA11035.1	1	Reactome: R-HSA-264876	"Insulin processing"
EFA06175.2	5	MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-6168;Reactome: R-HSA-196843	"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism"
EFA05408.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA12228.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA11159.2	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
EEZ99988.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EFA08276.1	13	Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
EFA09228.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events"
EFA10048.1	8	KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"T cell receptor signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
EFA11580.2	3	Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines"
KYB26560.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
EFA01753.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EFA03019.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
EFA03626.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EEZ97806.1	6	KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23	"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation"
EEZ98974.2	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
EFA06262.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
KYB28909.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA06982.2	1	Reactome: R-HSA-3295583	"TRP channels"
EFA10147.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
EFA05912.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978	"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)"
EFA07058.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
EFA02198.2	7	KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;MetaCyc: PWY-6471;MetaCyc: PWY-6470;MetaCyc: PWY-5265;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13	"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis"
EFA08806.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
KYB25935.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517	"Ca2+ pathway";"cGMP effects";"Rap1 signalling"
EEZ97432.2	6	Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex"
EEZ98930.1	4	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism"
EFA05664.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EFA00470.2	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
EEZ97959.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
EEZ98339.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
EFA05881.2	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
EFA07462.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA06803.2	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
KYB26787.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA03827.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EEZ98366.2	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
EFA12821.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
KYB25244.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EFA09734.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
KYB26085.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
EFA06321.2	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
EFA02417.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA06082.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA07440.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA07505.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EFA09266.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EFA03783.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic"
KYB26452.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ98804.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EFA04934.2	6	Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
EFA11927.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA12368.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA12126.2	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EFA12019.1	12	KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1	"Propanoate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism"
EFA03342.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
KYB26709.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
EFA03071.2	1	Reactome: R-HSA-1483166	"Synthesis of PA"
EFA07333.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EFA07887.2	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
KYB25650.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA04661.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
EEZ98866.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ99280.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EFA10438.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
KYB26772.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
KYB28004.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
EEZ97223.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
EFA05580.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA06587.2	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
EFA00625.1	1	Reactome: R-HSA-8876725	"Protein methylation"
EEZ98444.2	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
KYB27844.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA08405.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EFA10055.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EEZ99732.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
KYB28452.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
EFA07590.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EFA06066.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA05355.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA10957.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EFA01588.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EFA05203.2	31	Reactome: R-HSA-75105;MetaCyc: PWY-5147;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-7858;MetaCyc: PWYG-321;MetaCyc: PWY-7723;MetaCyc: PWY-5142;MetaCyc: PWY-6519;Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-4381;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-8049;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-5366;MetaCyc: PWY-7663	"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)"
EFA01136.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
EFA00504.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EEZ98647.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
EFA00451.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
EFA04453.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
KYB25552.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"G alpha (s) signalling events"
EFA10479.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EEZ97873.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
EEZ98675.1	7	MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism"
EEZ98597.1	13	Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902	"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)"
EFA09280.1	8	MetaCyc: PWY-6580;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-4661;MetaCyc: PWY-2301;MetaCyc: PWY-6372	"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
EFA07146.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane"
EFA03528.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
EEZ97998.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
KYB29375.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EEZ99767.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
EFA07500.2	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
EFA04537.1	1	Reactome: R-HSA-400253	"Circadian Clock"
EEZ97256.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
EFA04414.1	11	MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Tunicamycin biosynthesis"
EEZ99123.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
EFA01613.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA05873.2	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA12465.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA04660.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
EFA10352.2	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
EFA03316.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
KYB29537.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
KYB25197.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
EFA06115.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
EFA10347.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EEZ97400.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EFA11484.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
KYB27071.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
EFA09131.1	14	MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201	"Folate polyglutamylation";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Folate transformations I"
EFA00172.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
EEZ97257.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III"
EFA02397.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
EFA01732.2	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
EFA08452.1	2	KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384	"Pentose phosphate pathway";"Ethanol oxidation"
EEZ99199.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA12824.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
KYB27323.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
KYB25585.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA09437.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EFA11598.1	5	Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-376172	"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"DSCAM interactions"
EEZ98007.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
EFA03295.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
KXZ75754.1	1	Reactome: R-HSA-211981	"Xenobiotics"
EFA01249.2	27	Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-165054	"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA"
KYB26551.1	1	Reactome: R-HSA-1296061	"HCN channels"
EFA02533.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
EFA10011.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
KYB28746.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
EFA06952.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA04691.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA05532.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
KYB26824.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
EEZ98813.2	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport"
EFA00117.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA00422.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA09507.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693	"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling"
EFA11411.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EFA06648.2	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA"
EFA00242.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
KYB25415.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA07795.2	5	KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210	"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
KYB28863.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670	"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway"
EFA06988.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
KYB25392.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA06430.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
KYB27584.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EFA01344.2	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
KYB27768.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
KXZ75661.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
EFA06147.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
EFA08550.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
KYB27109.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
EFA04853.2	4	MetaCyc: PWY-7511;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Protein ubiquitination";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
EFA09133.1	3	MetaCyc: PWY-1269;Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism";"Lipopolysaccharide biosynthesis"
EFA03518.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-1268020	"Complex I biogenesis";"Mitochondrial protein import"
EFA04917.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
EFA01304.1	16	Reactome: R-HSA-3134963;Reactome: R-HSA-975138;Reactome: R-HSA-5603041;Reactome: R-HSA-975155;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-1257604;Reactome: R-HSA-5603037;Reactome: R-HSA-166058;Reactome: R-HSA-1236974;Reactome: R-HSA-1810476;Reactome: R-HSA-5602498;Reactome: R-HSA-975871;Reactome: R-HSA-975110;Reactome: R-HSA-6811558;Reactome: R-HSA-5602680	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"ER-Phagosome pathway";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 deficiency (TLR5)"
EFA00297.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EFA02517.2	26	Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657	"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Estrogen-dependent gene expression";"Attenuation phase";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes"
EEZ97656.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-7417	"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)"
KYB26193.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EEZ98442.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
KYB25309.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-6798695	"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation"
EFA02454.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
KYB25345.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
KYB26642.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5675221	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway"
EFA10789.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB25746.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
EFA11037.2	7	Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism"
EFA03418.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
KYB29552.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA09048.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
KYB29090.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EFA12664.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EFA05959.1	13	Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883	"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II"
EFA00608.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA08302.2	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
EFA09636.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
EFA01832.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA07893.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB29539.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
KYB26446.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
EFA03966.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA06343.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EFA09915.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EFA10815.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
KYB28091.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EEZ98522.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA00856.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ98112.1	7	MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
EFA00829.2	7	Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939	"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)"
EEZ97328.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB26518.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EEZ98497.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA08800.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA02262.1	4	MetaCyc: PWY-7394;MetaCyc: PWY-5691;MetaCyc: PWY-7849;KEGG: 00230+4.1.1.97	"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Purine metabolism"
KYB25286.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
EFA02907.2	1	Reactome: R-HSA-977443	"GABA receptor activation"
EFA07649.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA04613.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA06415.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
EFA07987.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
KYB27483.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210	"Regulation of HSF1-mediated heat shock response";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Translesion Synthesis by POLH";"Meiotic recombination";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
EFA08867.1	1	Reactome: R-HSA-264876	"Insulin processing"
EFA09317.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
KYB25739.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289	"Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation"
KYB27666.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
EFA06842.1	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
KYB26266.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EEZ98478.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB24711.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
KYB28333.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
EFA06694.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
EFA07381.1	1	Reactome: R-HSA-8949613	"Cristae formation"
KYB25373.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA02213.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
EFA07535.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
KYB26719.1	5	Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
EFA06863.2	13	KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Other glycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
EFA07279.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
KYB25938.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
KYB26318.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EFA08270.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EFA08993.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
KYB25522.1	10	KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-4321;Reactome: R-HSA-916853;MetaCyc: PWY-5022	"Propanoate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation III";"beta-Alanine metabolism";"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"L-glutamate degradation IV";"Degradation of GABA";"4-aminobutanoate degradation V"
EFA01243.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
EFA01805.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EFA05475.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EFA10506.1	16	MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-7218;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-5723;Reactome: R-HSA-70263	"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Gluconeogenesis"
EFA01288.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131	"Collagen degradation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR"
EFA07468.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-3232142;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of ubiquitinylation proteins";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
EFA06524.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA09594.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
EFA07958.1	17	Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair"
EEZ98330.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
EEZ98734.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
EFA11512.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA03917.1	21	MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7219;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7197	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation"
EFA10576.2	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
EFA07993.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
KYB29713.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
EFA04530.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB24597.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
EEZ99113.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EFA08780.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
EEZ97645.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
KYB29439.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
KYB29415.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
KYB26491.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA"
EFA07317.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane"
EFA02190.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
KYB25592.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
KYB29410.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling"
EFA04093.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
KYB27522.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB27777.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554	"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
EFA10912.2	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
EFA06331.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EFA04668.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
EFA08115.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
KYB25540.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
EFA04132.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA09907.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
KYB26628.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA06557.2	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
KYB25672.1	8	MetaCyc: PWY-7765;MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00630+3.5.1.9;MetaCyc: PWY-5651;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-7734	"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis"
KYB25893.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
EFA06724.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EEZ99967.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ99807.2	19	Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-6802946	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"RAF activation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants"
EFA00684.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
EFA05370.2	56	Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949	"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin"
KYB25245.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA10695.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EFA07749.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA03458.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA03437.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA01898.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA10229.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
EFA11546.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EFA05803.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EFA06763.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
EFA09147.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EFA09161.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5632684	"Activation of SMO";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state"
EFA05992.2	22	Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-195253	"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex"
EFA09517.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
EFA02482.1	18	KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-561;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37	"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism"
EFA03236.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EEZ99094.1	11	Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-72163;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862	"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
KYB27418.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
EFA12309.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism"
EEZ97976.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
EFA09849.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058	"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling"
KYB27036.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EEZ98443.2	6	MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6907	"Thiamine salvage III";"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)"
EFA10746.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA11391.2	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
EFA08795.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EFA11491.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA03647.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
EFA06197.2	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
KYB27324.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
EFA00911.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
KYB27573.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EFA05457.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA00579.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
EFA08456.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA06200.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837	"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation"
EFA05474.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
EFA06325.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EFA13323.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA04947.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
EFA07684.2	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
EFA04352.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
EFA10622.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6361;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis"
EFA11099.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
EEZ99272.2	16	Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-141430	"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex"
EFA07471.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
KYB26998.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
EFA08843.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
KYB29349.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
EFA11336.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
KXZ75838.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EFA06723.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA01121.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
KYB26017.1	1	Reactome: R-HSA-8964038	"LDL clearance"
EFA12371.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA06716.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
KYB26118.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
KYB29359.1	182	Reactome: R-HSA-1169408;Reactome: R-HSA-9013973;Reactome: R-HSA-8948751;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-8852276;Reactome: R-HSA-1236382;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5684264;Reactome: R-HSA-5696394;Reactome: R-HSA-6804760;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-9637628;Reactome: R-HSA-174084;Reactome: R-HSA-1295596;Reactome: R-HSA-983168;Reactome: R-HSA-937072;Reactome: R-HSA-4608870;Reactome: R-HSA-175474;Reactome: R-HSA-174048;Reactome: R-HSA-156902;Reactome: R-HSA-8939236;Reactome: R-HSA-1358803;Reactome: R-HSA-5357956;Reactome: R-HSA-3769402;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-5689896;Reactome: R-HSA-2122948;Reactome: R-HSA-445989;Reactome: R-HSA-187577;Reactome: R-HSA-5675221;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-9645460;Reactome: R-HSA-2467813;Reactome: R-HSA-174490;Reactome: R-HSA-400253;Reactome: R-HSA-975163;Reactome: R-HSA-5654726;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6791226;Reactome: R-HSA-211733;Reactome: R-HSA-977225;Reactome: R-HSA-3322077;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-2559585;Reactome: R-HSA-9013507;Reactome: R-HSA-202424;Reactome: R-HSA-72702;Reactome: R-HSA-8951664;Reactome: R-HSA-9633012;Reactome: R-HSA-6782210;Reactome: R-HSA-9636383;Reactome: R-HSA-209560;Reactome: R-HSA-5654727;Reactome: R-HSA-5689877;Reactome: R-HSA-174154;Reactome: R-HSA-3785653;Reactome: R-HSA-1234176;Reactome: R-HSA-2173795;Reactome: R-HSA-937041;Reactome: R-HSA-110312;Reactome: R-HSA-174184;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2565942;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-156827;Reactome: R-HSA-936440;Reactome: R-HSA-5358346;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-937042;Reactome: R-HSA-975957;Reactome: R-HSA-901032;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-179409;Reactome: R-HSA-975956;Reactome: R-HSA-532668;Reactome: R-HSA-1253288;Reactome: R-HSA-5693607;Reactome: R-HSA-1236974;Reactome: R-HSA-912631;Reactome: R-HSA-5685942;Reactome: R-HSA-2894862;Reactome: R-HSA-4641257;Reactome: R-HSA-2644606;Reactome: R-HSA-5696397;Reactome: R-HSA-8849469;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-937039;Reactome: R-HSA-6807004;Reactome: R-HSA-8939902;Reactome: R-HSA-2408557;Reactome: R-HSA-195253;Reactome: R-HSA-8876493;Reactome: R-HSA-4641263;Reactome: R-HSA-2173788;Reactome: R-HSA-5675482;Reactome: R-HSA-9033241;Reactome: R-HSA-72689;Reactome: R-HSA-8866654;Reactome: R-HSA-1169091;Reactome: R-HSA-8866652;Reactome: R-HSA-192823;Reactome: R-HSA-168638;Reactome: R-HSA-5693565;Reactome: R-HSA-5654733;Reactome: R-HSA-5658442;Reactome: R-HSA-205043;Reactome: R-HSA-72695;Reactome: R-HSA-2559580;Reactome: R-HSA-5696395;Reactome: R-HSA-168927;Reactome: R-HSA-936964;Reactome: R-HSA-6804757;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9613829;Reactome: R-HSA-8875360;Reactome: R-HSA-9604323;Reactome: R-HSA-8948747;Reactome: R-HSA-5654732;Reactome: R-HSA-975110;Reactome: R-HSA-6781827;Reactome: R-HSA-2173796;Reactome: R-HSA-450302;Reactome: R-HSA-382556;Reactome: R-HSA-72764;Reactome: R-HSA-975144;Reactome: R-HSA-2691232;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-6783310;Reactome: R-HSA-5689901;Reactome: R-HSA-5357905;Reactome: R-HSA-8863795;Reactome: R-HSA-69017;Reactome: R-HSA-201681;Reactome: R-HSA-162588;Reactome: R-HSA-182971;Reactome: R-HSA-75815;Reactome: R-HSA-2672351;Reactome: R-HSA-2979096;Reactome: R-HSA-69231;Reactome: R-HSA-168928;Reactome: R-HSA-5632684;Reactome: R-HSA-2122947;Reactome: R-HSA-5656169;Reactome: R-HSA-72649;Reactome: R-HSA-6804756;Reactome: R-HSA-174113;Reactome: R-HSA-3134975;Reactome: R-HSA-5655862;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-5205685;Reactome: R-HSA-8856825;Reactome: R-HSA-2173791;Reactome: R-HSA-6781823;Reactome: R-HSA-110320;Reactome: R-HSA-2559582;Reactome: R-HSA-68827;Reactome: R-HSA-69541;Reactome: R-HSA-72706	"ISG15 antiviral mechanism";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of PTEN stability and activity";"Aggrephagy";"Late endosomal microautophagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of RUNX3 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"DNA Damage Recognition in GG-NER";"Regulation of TP53 Activity through Methylation";"Ub-specific processing proteases";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Modulation by Mtb of host immune system";"Autodegradation of Cdh1 by Cdh1:APC/C";"Spry regulation of FGF signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Asymmetric localization of PCP proteins";"Assembly Of The HIV Virion";"APC/C:Cdc20 mediated degradation of Cyclin B";"Peptide chain elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of ERBB2:ERBB3 signaling";"TNFR1-induced NFkappaB signaling pathway";"Deactivation of the beta-catenin transactivating complex";"Vpu mediated degradation of CD4";"Iron uptake and transport";"Ovarian tumor domain proteases";"Activated NOTCH1 Transmits Signal to the Nucleus";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of MAPK pathway";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Alpha-protein kinase 1 signaling pathway";"Separation of Sister Chromatids";"Membrane binding and targetting of GAG proteins";"Circadian Clock";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Negative regulation of FGFR1 signaling";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Amyloid fiber formation";"Glycogen synthesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Oncogene Induced Senescence";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Downstream TCR signaling";"Ribosomal scanning and start codon recognition";"Neddylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Prevention of phagosomal-lysosomal fusion";"NF-kB is activated and signals survival";"Negative regulation of FGFR2 signaling";"Josephin domain DUBs";"APC/C:Cdc20 mediated degradation of Securin";"Myoclonic epilepsy of Lafora";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IKK complex recruitment mediated by RIP1";"Translesion synthesis by REV1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Regulation of PLK1 Activity at G2/M Transition";"Dual incision in TC-NER";"Translesion synthesis by POLI";"L13a-mediated translational silencing of Ceruloplasmin expression";"Negative regulators of DDX58/IFIH1 signaling";"Hedgehog ligand biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"IRAK2 mediated activation of TAK1 complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ER Quality Control Compartment (ERQC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"APC-Cdc20 mediated degradation of Nek2A";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downregulation of ERBB4 signaling";"Processing of DNA double-strand break ends";"ER-Phagosome pathway";"Regulation of signaling by CBL";"HDR through Homologous Recombination (HRR)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of AXIN";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"IRAK1 recruits IKK complex";"Negative regulation of MET activity";"Regulation of RUNX2 expression and activity";"Selenocysteine synthesis";"Degradation of beta-catenin by the destruction complex";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of FZD by ubiquitination";"Downregulation of TGF-beta receptor signaling";"Regulation of necroptotic cell death";"Peroxisomal protein import";"Formation of a pool of free 40S subunits";"E3 ubiquitin ligases ubiquitinate target proteins";"Activation of NF-kappaB in B cells";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Viral mRNA Translation";"NOD1/2 Signaling Pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of FGFR4 signaling";"Regulation of RAS by GAPs";"NRIF signals cell death from the nucleus";"Formation of the ternary complex, and subsequently, the 43S complex";"Oxidative Stress Induced Senescence";"Formation of Incision Complex in GG-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of TP53 Degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Chaperone Mediated Autophagy";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN localization";"Negative regulation of FGFR3 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"activated TAK1 mediates p38 MAPK activation";"ABC-family proteins mediated transport";"Eukaryotic Translation Termination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Fanconi Anemia Pathway";"Metalloprotease DUBs";"Regulation of TNFR1 signaling";"Downregulation of ERBB2 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"TCF dependent signaling in response to WNT";"Budding and maturation of HIV virion";"EGFR downregulation";"Ubiquitin-dependent degradation of Cyclin D";"Stimuli-sensing channels";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Hedgehog 'on' state";"NOTCH1 Intracellular Domain Regulates Transcription";"Termination of translesion DNA synthesis";"Translation initiation complex formation";"Regulation of TP53 Activity through Phosphorylation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of innate immune responses to cytosolic DNA";"Translesion synthesis by POLK";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Pink/Parkin Mediated Mitophagy";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Formation of TC-NER Pre-Incision Complex";"Translesion Synthesis by POLH";"Senescence-Associated Secretory Phenotype (SASP)";"CDT1 association with the CDC6:ORC:origin complex";"Stabilization of p53";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EFA01582.2	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
KYB26625.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Separation of Sister Chromatids";"Cilium Assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Kinesins";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy"
KYB27624.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB25669.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA09905.2	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
EFA01340.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
EFA11263.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-2132295	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation"
EFA00114.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
EFA07408.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
KXZ75917.1	7	MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
KYB28437.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
EFA11602.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
KYB29551.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA10597.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB28411.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EFA03472.1	1	Reactome: R-HSA-8951664	"Neddylation"
EEZ97530.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
EFA13038.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
EEZ97484.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
EEZ98786.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB26892.1	14	Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924;Reactome: R-HSA-2467813;Reactome: R-HSA-1632852	"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Separation of Sister Chromatids";"Macroautophagy"
EFA04635.2	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
EFA13584.2	8	KEGG: 04660+2.7.10.2;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"T cell receptor signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
KYB27131.1	10	MetaCyc: PWY-5849;MetaCyc: PWY-5891;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-7996	"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I"
EEZ98513.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
KXZ75660.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
EFA01564.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
KXZ75737.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
EFA08581.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
EFA08917.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA00421.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
EFA03379.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
EFA03487.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA02010.1	1	Reactome: R-HSA-156588	"Glucuronidation"
KYB25871.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
EFA01325.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EEZ99522.2	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
KYB26571.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA07198.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
KYB26515.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA03598.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
KYB27868.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
KYB29638.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
KYB27803.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
EFA10737.2	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
EFA06522.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
EFA03067.1	1	Reactome: R-HSA-5676934	"Protein repair"
EFA10485.1	1	Reactome: R-HSA-8949613	"Cristae formation"
EFA08385.2	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
EFA00826.2	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EFA05090.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
KYB29061.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
EEZ98089.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA05681.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579	"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange"
EFA09487.1	12	MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
EFA13210.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EFA10969.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
KYB27587.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EFA07904.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EFA08069.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
EFA00828.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847	"UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones"
KYB25845.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA06191.2	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
EFA02356.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
EFA11363.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EFA04922.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB26567.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA12890.2	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
EFA05186.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA00339.1	8	MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1	"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine salvage";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II"
EFA03967.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA10102.2	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA06381.2	8	Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676	"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
KYB28971.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EFA01369.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
KYB27978.1	9	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
EFA00783.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA09309.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EFA08271.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EFA12616.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
KYB29800.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA11141.2	27	Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-5619107	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
EFA06836.2	13	Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
EFA05977.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs"
EEZ98980.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA02466.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EFA00405.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EFA03441.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
KYB25745.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
EFA10926.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA02278.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EFA01987.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
KYB28974.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
EFA02005.2	5	MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis"
EFA09778.2	6	Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
EFA03406.1	1	Reactome: R-HSA-446199	"Synthesis of Dolichyl-phosphate"
EFA05049.2	14	Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665;Reactome: R-HSA-6798695;Reactome: R-HSA-977225	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells";"Neutrophil degranulation";"Amyloid fiber formation"
EFA03463.2	12	MetaCyc: PWY-5743;MetaCyc: PWY-7384;Reactome: R-HSA-71032;MetaCyc: PWYG-321;KEGG: 00640+6.4.1.3;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.3;Reactome: R-HSA-3371599;KEGG: 00280+6.4.1.3;Reactome: R-HSA-196780;KEGG: 00630+6.4.1.3;MetaCyc: PWY-6728	"3-hydroxypropanoate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propionyl-CoA catabolism";"";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Valine, leucine and isoleucine degradation";"Biotin transport and metabolism";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle"
EEZ97218.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
EFA04626.2	14	Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
EFA02795.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EFA02729.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA12136.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EFA00011.2	6	Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8874211	"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes"
EFA00305.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
EFA08717.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
EFA10830.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
KYB25970.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
EFA05321.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EEZ99264.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
EFA06942.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA08955.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
EFA05068.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
EFA03937.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA07434.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
EFA12251.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
EFA01876.2	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
EFA05103.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
EFA12998.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EFA10582.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
KYB28051.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
EFA01868.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
KYB27567.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EEZ99709.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
KYB25598.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
EFA06247.2	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
EFA00043.2	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EFA05862.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
EFA06676.2	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
EFA06805.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
EFA02878.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA08516.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975	"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA"
EFA02249.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
EFA05645.1	1	Reactome: R-HSA-525793	"Myogenesis"
EFA06970.1	4	MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20	"Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism"
EEZ99189.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EFA02145.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
KYB25791.1	17	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"Meiotic synapsis";"Processing of DNA double-strand break ends"
EFA13616.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EFA07110.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-983168	"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB26030.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
KYB24935.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40	"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism"
EFA01477.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
EEZ97194.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
KYB25588.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB29823.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EEZ98455.2	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
KYB28050.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
KYB27085.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA08249.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA05324.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
EFA04473.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
EFA07651.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
EEZ97810.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
KYB26937.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EFA10708.1	44	Reactome: R-HSA-112409;Reactome: R-HSA-8939211;Reactome: R-HSA-9649948;Reactome: R-HSA-445144;Reactome: R-HSA-5674499;Reactome: R-HSA-5654727;Reactome: R-HSA-375165;Reactome: R-HSA-982772;Reactome: R-HSA-879415;Reactome: R-HSA-198753;Reactome: R-HSA-202670;Reactome: R-HSA-2559585;Reactome: R-HSA-2871796;Reactome: R-HSA-162658;Reactome: R-HSA-5673001;Reactome: R-HSA-3371453;Reactome: R-HSA-8943724;Reactome: R-HSA-456926;Reactome: R-HSA-881907;Reactome: R-HSA-9634638;Reactome: R-HSA-5674135;Reactome: R-HSA-5654732;Reactome: R-HSA-6802948;Reactome: R-HSA-5668599;Reactome: R-HSA-5654726;Reactome: R-HSA-2029482;Reactome: R-HSA-74749;Reactome: R-HSA-170968;Reactome: R-HSA-5675221;Reactome: R-HSA-9627069;Reactome: R-HSA-6802952;Reactome: R-HSA-444257;Reactome: R-HSA-2559582;Reactome: R-HSA-450341;Reactome: R-HSA-6802955;Reactome: R-HSA-2559580;Reactome: R-HSA-6802946;Reactome: R-HSA-5654733;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-9635465;KEGG: 04150+2.7.11.24;Reactome: R-HSA-8940973;Reactome: R-HSA-1295596	"RAF-independent MAPK1/3 activation";"ESR-mediated signaling";"Signaling downstream of RAS mutants";"Signal transduction by L1";"Negative feedback regulation of MAPK pathway";"Negative regulation of FGFR2 signaling";"NCAM signaling for neurite out-growth";"Growth hormone receptor signaling";"Advanced glycosylation endproduct receptor signaling";"ERK/MAPK targets";"ERKs are inactivated";"Oncogene Induced Senescence";"FCERI mediated MAPK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"RAF/MAP kinase cascade";"Regulation of HSF1-mediated heat shock response";"Regulation of PTEN gene transcription";"Thrombin signalling through proteinase activated receptors (PARs)";"Gastrin-CREB signalling pathway via PKC and MAPK";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAP2K and MAPK activation";"Negative regulation of FGFR3 signaling";"Signaling by high-kinase activity BRAF mutants";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR1 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Signal attenuation";"Frs2-mediated activation";"Negative regulation of MAPK pathway";"Regulation of the apoptosome activity";"Signaling by BRAF and RAF fusions";"RSK activation";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of the AP-1 family of transcription factors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Oxidative Stress Induced Senescence";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR4 signaling";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Suppression of apoptosis";"mTOR signaling pathway";"RUNX2 regulates osteoblast differentiation";"Spry regulation of FGF signaling"
EFA00436.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB27641.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
KYB27916.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA09565.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB27758.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism"
EEZ99435.2	10	Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2197563	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription"
EFA09231.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
KYB25695.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA10061.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA01280.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
EFA06186.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
EFA06829.2	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
KYB25253.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
KYB28202.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EEZ99114.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA03226.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB25482.1	7	MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25	"Starch degradation II";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch and sucrose metabolism"
EFA02053.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EFA05154.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA07855.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-429947;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
EFA07176.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
EFA03628.1	11	Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378	"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling"
EFA11147.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA00919.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-936440;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555	"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation"
EFA09390.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
KYB24939.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
EFA00652.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4549349	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
EEZ98574.2	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
EFA09145.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
KYB25638.1	2	Reactome: R-HSA-6809371;Reactome: R-HSA-420499	"Formation of the cornified envelope";"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EFA03529.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
KYB27920.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
EFA05697.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA08995.1	9	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II"
EFA06894.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
KYB25596.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EEZ98651.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
EFA05121.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
KYB29132.1	9	KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III"
EEZ97534.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EEZ98203.2	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
KYB26957.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
EFA10288.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200	"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
EFA12936.1	7	MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25	"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
EFA00406.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
KYB28382.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
EFA01355.2	11	Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604	"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling"
EEZ97472.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EEZ97427.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
KYB29360.1	182	Reactome: R-HSA-912631;Reactome: R-HSA-5685942;Reactome: R-HSA-2894862;Reactome: R-HSA-179409;Reactome: R-HSA-5676590;Reactome: R-HSA-532668;Reactome: R-HSA-975956;Reactome: R-HSA-5693607;Reactome: R-HSA-1253288;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-937039;Reactome: R-HSA-6807004;Reactome: R-HSA-8939902;Reactome: R-HSA-2644606;Reactome: R-HSA-4641257;Reactome: R-HSA-5696397;Reactome: R-HSA-8849469;Reactome: R-HSA-69601;Reactome: R-HSA-8866652;Reactome: R-HSA-5693565;Reactome: R-HSA-5654733;Reactome: R-HSA-192823;Reactome: R-HSA-168638;Reactome: R-HSA-205043;Reactome: R-HSA-72695;Reactome: R-HSA-5658442;Reactome: R-HSA-8876493;Reactome: R-HSA-4641263;Reactome: R-HSA-2408557;Reactome: R-HSA-195253;Reactome: R-HSA-72689;Reactome: R-HSA-8866654;Reactome: R-HSA-2173788;Reactome: R-HSA-5675482;Reactome: R-HSA-9033241;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-6804757;Reactome: R-HSA-5610785;Reactome: R-HSA-9613829;Reactome: R-HSA-8948747;Reactome: R-HSA-9604323;Reactome: R-HSA-8875360;Reactome: R-HSA-2559580;Reactome: R-HSA-168927;Reactome: R-HSA-5696395;Reactome: R-HSA-936964;Reactome: R-HSA-975144;Reactome: R-HSA-5362768;Reactome: R-HSA-2691232;Reactome: R-HSA-6783310;Reactome: R-HSA-2871837;Reactome: R-HSA-5689901;Reactome: R-HSA-5654732;Reactome: R-HSA-6781827;Reactome: R-HSA-975110;Reactome: R-HSA-2173796;Reactome: R-HSA-72764;Reactome: R-HSA-450302;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-182971;Reactome: R-HSA-162588;Reactome: R-HSA-69231;Reactome: R-HSA-2979096;Reactome: R-HSA-2672351;Reactome: R-HSA-5632684;Reactome: R-HSA-168928;Reactome: R-HSA-5357905;Reactome: R-HSA-8863795;Reactome: R-HSA-201681;Reactome: R-HSA-69017;Reactome: R-HSA-6804756;Reactome: R-HSA-72649;Reactome: R-HSA-3134975;Reactome: R-HSA-174113;Reactome: R-HSA-5655862;Reactome: R-HSA-2122947;Reactome: R-HSA-5656169;Reactome: R-HSA-69541;Reactome: R-HSA-72706;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-5205685;Reactome: R-HSA-6781823;Reactome: R-HSA-2173791;Reactome: R-HSA-8856825;Reactome: R-HSA-2559582;Reactome: R-HSA-68827;Reactome: R-HSA-110320;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5684264;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-1169408;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-1236382;Reactome: R-HSA-9615710;Reactome: R-HSA-8948751;Reactome: R-HSA-9013973;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-5607761;Reactome: R-HSA-5696394;Reactome: R-HSA-6804760;Reactome: R-HSA-983168;Reactome: R-HSA-175474;Reactome: R-HSA-4608870;Reactome: R-HSA-937072;Reactome: R-HSA-174048;Reactome: R-HSA-156902;Reactome: R-HSA-69481;Reactome: R-HSA-1295596;Reactome: R-HSA-174084;Reactome: R-HSA-9637628;Reactome: R-HSA-187577;Reactome: R-HSA-5675221;Reactome: R-HSA-2122948;Reactome: R-HSA-445989;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-9645460;Reactome: R-HSA-2467813;Reactome: R-HSA-5654726;Reactome: R-HSA-5696400;Reactome: R-HSA-975163;Reactome: R-HSA-400253;Reactome: R-HSA-174490;Reactome: R-HSA-8939236;Reactome: R-HSA-1358803;Reactome: R-HSA-3769402;Reactome: R-HSA-180534;Reactome: R-HSA-5357956;Reactome: R-HSA-5689896;Reactome: R-HSA-917937;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-2559585;Reactome: R-HSA-202424;Reactome: R-HSA-9013507;Reactome: R-HSA-110314;Reactome: R-HSA-211733;Reactome: R-HSA-6791226;Reactome: R-HSA-3322077;Reactome: R-HSA-450408;Reactome: R-HSA-977225;Reactome: R-HSA-9636383;Reactome: R-HSA-6782210;Reactome: R-HSA-9633012;Reactome: R-HSA-5654727;Reactome: R-HSA-5689877;Reactome: R-HSA-209560;Reactome: R-HSA-1234176;Reactome: R-HSA-3785653;Reactome: R-HSA-174154;Reactome: R-HSA-72702;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-110312;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2565942;Reactome: R-HSA-2173795;Reactome: R-HSA-937041;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-937042;Reactome: R-HSA-975957;Reactome: R-HSA-174178;Reactome: R-HSA-901032;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-936440;Reactome: R-HSA-156827;Reactome: R-HSA-5358346	"Regulation of signaling by CBL";"HDR through Homologous Recombination (HRR)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"APC-Cdc20 mediated degradation of Nek2A";"NIK-->noncanonical NF-kB signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Processing of DNA double-strand break ends";"Downregulation of ERBB4 signaling";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"IRAK1 recruits IKK complex";"Negative regulation of MET activity";"Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of AXIN";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of FGFR4 signaling";"Viral mRNA Translation";"NOD1/2 Signaling Pathway";"NRIF signals cell death from the nucleus";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of RAS by GAPs";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of FZD by ubiquitination";"Selenocysteine synthesis";"Degradation of beta-catenin by the destruction complex";"Formation of a pool of free 40S subunits";"E3 ubiquitin ligases ubiquitinate target proteins";"Downregulation of TGF-beta receptor signaling";"Regulation of necroptotic cell death";"Peroxisomal protein import";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Regulation of TP53 Degradation";"GLI3 is processed to GLI3R by the proteasome";"Chaperone Mediated Autophagy";"Regulation of PTEN localization";"Negative regulation of NOTCH4 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Oxidative Stress Induced Senescence";"TICAM1, RIP1-mediated IKK complex recruitment";"Formation of Incision Complex in GG-NER";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Fanconi Anemia Pathway";"FCERI mediated NF-kB activation";"Metalloprotease DUBs";"Negative regulation of FGFR3 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Eukaryotic Translation Termination";"activated TAK1 mediates p38 MAPK activation";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"EGFR downregulation";"Budding and maturation of HIV virion";"Cyclin D associated events in G1";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Stimuli-sensing channels";"Hedgehog 'on' state";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of TNFR1 signaling";"Downregulation of ERBB2 signaling";"TCF dependent signaling in response to WNT";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of TP53 Activity through Phosphorylation";"Translation initiation complex formation";"Regulation of innate immune responses to cytosolic DNA";"SCF-beta-TrCP mediated degradation of Emi1";"Translesion synthesis by POLK";"NOTCH1 Intracellular Domain Regulates Transcription";"Termination of translesion DNA synthesis";"Stabilization of p53";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Pink/Parkin Mediated Mitophagy";"Formation of TC-NER Pre-Incision Complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Cargo recognition for clathrin-mediated endocytosis";"Senescence-Associated Secretory Phenotype (SASP)";"CDT1 association with the CDC6:ORC:origin complex";"Translesion Synthesis by POLH";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ISG15 antiviral mechanism";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Late endosomal microautophagy";"Regulation of PTEN stability and activity";"TICAM1-dependent activation of IRF3/IRF7";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"Dectin-1 mediated noncanonical NF-kB signaling";"DNA Damage Recognition in GG-NER";"Regulation of TP53 Activity through Methylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Assembly Of The HIV Virion";"Asymmetric localization of PCP proteins";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Peptide chain elongation";"G2/M Checkpoints";"Spry regulation of FGF signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Modulation by Mtb of host immune system";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of MAPK pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Alpha-protein kinase 1 signaling pathway";"Separation of Sister Chromatids";"Negative regulation of FGFR1 signaling";"Dual Incision in GG-NER";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Circadian Clock";"Membrane binding and targetting of GAG proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of ERBB2:ERBB3 signaling";"Deactivation of the beta-catenin transactivating complex";"Vpu mediated degradation of CD4";"TNFR1-induced NFkappaB signaling pathway";"Ovarian tumor domain proteases";"Iron uptake and transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Oncogene Induced Senescence";"Downstream TCR signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Glycogen synthesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Amyloid fiber formation";"Prevention of phagosomal-lysosomal fusion";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Negative regulation of FGFR2 signaling";"Josephin domain DUBs";"NF-kB is activated and signals survival";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Myoclonic epilepsy of Lafora";"APC/C:Cdc20 mediated degradation of Securin";"Ribosomal scanning and start codon recognition";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Translesion synthesis by REV1";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Regulation of PLK1 Activity at G2/M Transition";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IKK complex recruitment mediated by RIP1";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"IRAK2 mediated activation of TAK1 complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER Quality Control Compartment (ERQC)";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Negative regulators of DDX58/IFIH1 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Hedgehog ligand biogenesis"
EFA02865.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
EFA04520.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
EFA11869.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
EFA07066.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
EFA06061.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA10585.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA08028.2	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
EEZ98305.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA00894.1	1	Reactome: R-HSA-373760	"L1CAM interactions"
KYB25454.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)"
EFA10731.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
EFA06486.2	6	Reactome: R-HSA-400253;MetaCyc: PWY-7927;Reactome: R-HSA-1614558;KEGG: 00920+2.8.1.1;MetaCyc: PWY-5350;Reactome: R-HSA-2151201	"Circadian Clock";"Sulfide oxidation IV (mitochondria)";"Degradation of cysteine and homocysteine";"Sulfur metabolism";"Thiosulfate disproportionation IV (rhodanese)";"Transcriptional activation of mitochondrial biogenesis"
EFA00356.2	1	Reactome: R-HSA-5617833	"Cilium Assembly"
EFA04441.1	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
EFA13370.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EEZ98137.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA01638.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
EFA09643.1	4	MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072	"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization"
EFA04506.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
EFA11378.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
EFA06909.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
EFA12181.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
KYB26997.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497	"Platelet sensitization by LDL";"Chylomicron remodeling";"Scavenging by Class F Receptors";"VLDL clearance";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"LDL remodeling";"LDL clearance";"Chylomicron clearance";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors"
EFA04972.1	19	KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-6969;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37	"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Pyruvate metabolism"
KYB26510.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
EFA01589.2	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
KYB25556.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378	"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling"
EFA05024.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
EEZ99237.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
KYB25021.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EFA01263.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
EFA06357.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA03159.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
EFA10394.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
KYB25760.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
KYB26650.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
EFA05820.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
EFA07280.1	11	MetaCyc: PWY-6859;MetaCyc: PWY-7391;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-6174;Reactome: R-HSA-191273;KEGG: 00900+5.3.3.2;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-922;MetaCyc: PWY-7524	"All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)"
EFA07117.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EFA09264.2	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
EFA00584.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
KYB27110.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7589	"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)"
KYB25771.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA05897.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
EFA02812.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA04324.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ97214.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA13692.2	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
EEZ97987.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
EFA05577.2	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
KYB25071.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins"
EFA03398.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EEZ97925.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin"
KYB26388.1	10	Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
EFA08376.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
KYB28925.1	17	Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210	"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
EFA02668.2	8	Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
EFA01469.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
EEZ97229.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148	"Mitotic Prometaphase";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Gap junction assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
KYB26197.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EFA04896.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA08849.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
EEZ99453.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
KYB25145.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EFA10943.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA03565.2	4	MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
KXZ75683.1	12	KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416	"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
EFA08584.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
EFA01865.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA11561.2	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
EFA07378.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA12881.2	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
EFA04898.1	5	KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305	"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D"
EFA08719.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EEZ97370.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
EEZ99808.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ99517.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
KYB29508.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ97401.2	1	Reactome: R-HSA-5635838	"Activation of SMO"
EFA01616.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EEZ98785.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA12460.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I"
EFA01911.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
EEZ97605.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
EFA06410.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
EEZ98676.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
EFA00591.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
EFA07586.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
KYB25532.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA00685.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
KYB28464.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
KYB28440.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA00323.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EFA03150.1	52	Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
EFA07587.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EFA12413.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EEZ99200.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EFA10251.2	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
EEZ99473.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EFA01493.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
KYB26600.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA02388.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
EFA10768.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
EFA03620.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
EFA08206.2	8	MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
KYB25778.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes"
EFA00508.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
EFA01806.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
EFA09444.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA02135.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA02535.2	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EFA03750.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5392	"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II"
EFA10918.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
EEZ99675.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
KYB26031.1	4	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00970+6.1.1.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Aminoacyl-tRNA biosynthesis";"Folate biosynthesis"
EFA10939.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
KYB26469.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
EFA07763.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901	"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation"
EFA06359.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
EFA10237.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
KYB26474.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA07750.2	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex"
EFA05884.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA12997.1	11	Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-75955	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation"
KYB25712.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
EFA10996.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-2151201;Reactome: R-HSA-3214858;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1368082	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional activation of mitochondrial biogenesis";"RMTs methylate histone arginines";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Circadian Clock";"RORA activates gene expression"
KYB29134.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EFA08670.2	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
EFA00084.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
EFA07122.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
EEZ97277.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB28199.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EFA06877.2	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
KYB28374.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
EFA06293.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA00603.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6796648	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes"
EFA11044.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
EFA00906.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ97980.2	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
KYB25335.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA04339.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EFA01736.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA01617.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA04683.1	14	Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7254;MetaCyc: PWY-561	"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Oxidative phosphorylation";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation"
KYB29733.1	1	Reactome: R-HSA-5578775	"Ion homeostasis"
EFA03009.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
EFA05960.2	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
EEZ97202.2	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
KYB28010.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
EEZ97352.2	4	MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
EFA02908.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1"
EFA09678.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
EFA02305.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA05525.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA00737.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EFA12278.1	12	MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
EFA05377.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
EFA10047.2	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
EFA06693.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
EFA10054.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA01677.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
KYB26002.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385	"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)"
EFA07149.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA09585.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
KYB28643.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
KYB28884.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
EEZ98663.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
EFA01262.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
EFA08218.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
EFA04508.1	8	MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142	"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
EFA05233.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
EFA10059.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB26275.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
EFA01964.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB28676.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EFA05205.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
EFA01760.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
EFA04946.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
KYB25357.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA08945.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
KYB27541.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
EFA07911.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
KYB29903.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA04016.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
EFA07843.2	10	KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695	"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"HS-GAG degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation"
EFA00624.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
EFA00128.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA10125.2	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes"
EFA06294.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA00605.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-5619107	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
KYB28006.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ99063.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
EEZ98296.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA02977.2	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA00567.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
EFA05082.1	4	KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16	"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism"
EEZ98657.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
EEZ97450.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
EFA00450.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EFA04686.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA08453.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
EFA05189.1	6	Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253	"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock"
EFA10155.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29092.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
KYB26617.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
EFA06291.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
EFA04892.1	3	Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271	"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
EEZ97876.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783	"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome"
KYB27556.1	57	Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837	"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation"
KXZ75648.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
KYB26307.1	20	MetaCyc: PWY-5856;MetaCyc: PWY-7922;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;Reactome: R-HSA-5173105;MetaCyc: PWY-5855;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;Reactome: R-HSA-5083633;MetaCyc: PWY-5872;MetaCyc: PWY-5871;KEGG: 00515+2.4.1.109;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;MetaCyc: PWY-7921	"Ubiquinol-9 biosynthesis (prokaryotic)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"O-linked glycosylation";"Ubiquinol-7 biosynthesis (prokaryotic)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Mannose type O-glycan biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Protein O-mannosylation I (yeast)"
KYB26820.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB27786.1	14	Reactome: R-HSA-399997;MetaCyc: PWY-6351;Reactome: R-HSA-4086398;MetaCyc: PWY-8052;Reactome: R-HSA-500657;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-434316;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367	"Acetylcholine regulates insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"PLC beta mediated events";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism"
EFA03164.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA08527.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
EFA12950.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA07237.1	7	MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3	"Folate transformations II (plants)";"Folate transformations I";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate polyglutamylation";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes"
KYB26487.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA01434.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA12349.2	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway"
EFA10106.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EEZ97313.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
EFA09116.1	10	Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644	"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair"
EFA01248.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
EEZ98848.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA13316.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA04531.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB26252.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
KYB29170.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-622	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis"
EFA06747.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA07318.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
EFA08175.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EFA03156.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ98713.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
EFA08404.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA00378.2	6	KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I"
EFA11494.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA07842.1	10	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23	"Neutrophil degranulation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Galactose metabolism"
KYB29836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29699.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EFA06070.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EFA00341.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Neutrophil degranulation"
EFA12812.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EFA05567.1	4	KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
EFA11133.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EFA08132.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA06933.2	9	Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.25;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23	"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism"
EFA02108.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
EFA06250.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EEZ98162.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ97473.2	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
EFA12882.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria"
EFA09576.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69091	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching"
EFA01191.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
EFA12840.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
KYB24989.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
EEZ99821.1	11	MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2	"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism"
KYB25554.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359	"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation"
EFA04786.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA10738.2	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
EFA02333.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EEZ98075.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
KYB27183.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
EFA03060.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA02617.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EFA04623.2	10	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-6799198;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69205	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Complex I biogenesis";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching";"G1/S-Specific Transcription"
EFA09169.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
EFA04159.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation"
EEZ97329.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA07482.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB26875.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
EFA05604.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway"
EFA11080.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722	"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis"
EEZ97576.1	6	MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1	"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms"
EEZ98116.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
EEZ99735.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
EFA07476.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
KYB28384.1	6	Reactome: R-HSA-5609978;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12	"Defective GALT can cause Galactosemia";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism"
EEZ99059.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA04759.2	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
EFA03107.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA07432.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
EEZ97816.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
EFA04897.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
EFA11622.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
KYB25039.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
KYB28596.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha"
EFA02216.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ98950.2	33	MetaCyc: PWY-6802;MetaCyc: PWY-5079;MetaCyc: PWY-7013;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-7798;MetaCyc: PWY-5078;MetaCyc: PWY-6342;MetaCyc: PWY-5057;MetaCyc: PWY-5082;MetaCyc: PWY-1801;KEGG: 00260+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00350+1.1.1.1;Reactome: R-HSA-71384;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6871;KEGG: 00680+1.1.1.284;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5480;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-6313;MetaCyc: PWY-3162;MetaCyc: PWY-6333;MetaCyc: PWY-6587	"Salidroside biosynthesis";"L-phenylalanine degradation III";"(S)-propane-1,2-diol degradation";"Chloroalkane and chloroalkene degradation";"L-leucine degradation III";"Fatty acid degradation";"Phenylethanol biosynthesis";"Protein S-nitrosylation and denitrosylation";"L-isoleucine degradation II";"Noradrenaline and adrenaline degradation";"L-valine degradation II";"L-methionine degradation III";"Formaldehyde oxidation II (glutathione-dependent)";"Glycine, serine and threonine metabolism";"alpha-Linolenic acid metabolism";"Metabolism of xenobiotics by cytochrome P450";"Chitin degradation to ethanol";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"Tyrosine metabolism";"Ethanol oxidation";"Glycolysis / Gluconeogenesis";"3-methylbutanol biosynthesis (engineered)";"Methane metabolism";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)";"Pyruvate fermentation to ethanol I";"Retinol metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"L-tryptophan degradation V (side chain pathway)";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol III"
EFA00158.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
EFA07054.2	14	MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-1483191	"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Sphingolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PC"
KYB26394.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA08856.2	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"G0 and Early G1"
KYB28926.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174437;Reactome: R-HSA-69166	"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate"
KYB29556.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EFA03133.1	6	KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
KYB28056.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EFA04169.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA01569.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176409	"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins"
EFA03093.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Ub-specific processing proteases";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
KYB25254.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
EFA07755.2	6	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
EEZ99191.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA09272.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
KYB27000.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
EFA06518.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
EFA10040.1	1	Reactome: R-HSA-8951664	"Neddylation"
KYB25316.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA10016.2	6	KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;MetaCyc: PWY-7165	"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)"
EFA06771.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Selenocompound metabolism"
EFA06943.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB25187.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA10132.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
EFA12467.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
KYB25486.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
EEZ99510.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
KYB25767.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
KYB26333.1	4	MetaCyc: PWY-5030;Reactome: R-HSA-70921;KEGG: 00340+4.3.1.3;MetaCyc: PWY-5028	"L-histidine degradation III";"Histidine catabolism";"Histidine metabolism";"L-histidine degradation II"
KYB27586.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EFA07854.2	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
EFA09534.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
KYB29721.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EFA01784.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EFA08704.1	1	Reactome: R-HSA-8951664	"Neddylation"
KYB25565.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EFA08256.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA08097.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
KYB25235.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
EFA06745.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EFA00645.1	8	Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750	"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6"
EFA02821.2	1	Reactome: R-HSA-211981	"Xenobiotics"
EFA02541.1	6	Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-6731;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1	"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation V";"Starch degradation III";"Glycogen degradation II";"Starch and sucrose metabolism"
EFA05670.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
KYB25144.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EEZ99659.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
EFA09426.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EEZ98981.2	10	KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism"
KYB29567.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
EFA00571.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
EFA12827.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EFA06106.1	6	Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606	"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation II"
KYB26663.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EEZ99270.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB28317.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB25934.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
KYB29654.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427	"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins"
KYB29592.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EFA04406.2	13	Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-416572;Reactome: R-HSA-4420097	"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway"
EFA02064.2	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
EFA07129.2	6	MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5743	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle"
KYB25426.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA11678.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA03774.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB28985.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
EEZ97347.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
EFA02444.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA04983.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA07687.2	22	MetaCyc: PWY-621;MetaCyc: PWY-6981;Reactome: R-HSA-70263;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-5659;MetaCyc: PWY-8013;MetaCyc: PWY-5054;MetaCyc: PWY-5384;MetaCyc: PWY-6142;KEGG: 00500+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-6992;Reactome: R-HSA-6798695;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5514;MetaCyc: PWY-622;Reactome: R-HSA-5628897	"Sucrose degradation III (sucrose invertase)";"Chitin biosynthesis";"Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"D-sorbitol biosynthesis I";"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"1,5-anhydrofructose degradation";"Neutrophil degranulation";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Starch biosynthesis";"TP53 Regulates Metabolic Genes"
EFA04400.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-5855	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)"
KYB25950.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
EFA05476.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EFA02123.1	8	Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
KYB25027.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EFA08543.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EFA05235.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
EEZ97398.2	32	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-167290	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation"
EEZ98716.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EFA09305.2	5	Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
EFA04229.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EEZ98057.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
EFA05856.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EFA11834.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB28401.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5619107	"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
EFA12420.2	20	Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
KYB27801.1	17	Reactome: R-HSA-9639288;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689	"Amino acids regulate mTORC1";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits"
EFA04525.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7589	"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)"
EEZ98328.2	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
EFA09998.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
EFA03956.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA08008.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EEZ97851.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
EEZ99918.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
EFA00313.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
EFA11450.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA07968.1	12	MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
EFA06840.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA03627.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
KYB29922.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
EFA03147.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
EFA01357.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA10794.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA04772.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
KYB26087.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
EFA03438.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA02007.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
EFA08595.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA00204.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA07752.1	8	Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
EFA03064.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
KYB29649.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EEZ99820.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
EFA01165.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EFA09738.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EFA02124.1	10	KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;MetaCyc: PWY-6365;MetaCyc: PWY-6362;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855167;MetaCyc: PWY-6366;Reactome: R-HSA-1855204;MetaCyc: PWY-4661	"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
KYB26083.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
EFA06898.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
EFA02300.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA06042.1	26	Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-6804114;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-8866654;Reactome: R-HSA-5656169;Reactome: R-HSA-69205;Reactome: R-HSA-4615885;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-174414;Reactome: R-HSA-1362277;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-5358565	"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"E3 ubiquitin ligases ubiquitinate target proteins";"Termination of translesion DNA synthesis";"G1/S-Specific Transcription";"SUMOylation of DNA replication proteins";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Processive synthesis on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
KYB26661.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EFA12359.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
KYB24867.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA06311.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
EEZ99485.2	4	KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
EEZ99479.1	13	KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6370;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261	"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle"
EFA03885.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EFA00411.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
EEZ98297.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685	"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy"
EEZ97696.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB29333.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA11143.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
EEZ97247.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
KYB25998.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EFA06578.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA07851.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
KYB26357.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA03021.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
KYB24844.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
EFA03825.1	13	MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
EFA02897.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
EFA07428.1	6	KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980	"Photosynthesis";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Cristae formation";"ATP biosynthesis"
EFA03829.2	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
KYB26686.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
EEZ98759.2	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
EFA02017.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
EFA02290.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
KYB26199.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
EFA08251.1	5	KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
EFA02685.2	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation"
EFA10861.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA13274.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
KYB25635.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
KYB26644.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
EFA06615.2	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
EFA07507.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
KYB29566.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
KYB25046.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
EFA11589.2	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
EFA03634.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EFA13468.1	12	MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
EFA07988.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA08534.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
EFA05071.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
EFA08805.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
KYB26428.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway"
KYB27940.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA05626.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
EFA09832.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EFA08150.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
EFA00210.2	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
KYB28989.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
EFA01959.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
EFA11366.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA09807.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
EFA03383.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA08829.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
KYB29663.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
EFA00429.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA03329.2	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
EFA04076.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EFA02214.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA02141.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EFA06934.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA13202.2	7	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-606279	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere"
KYB28977.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
EFA01802.1	6	Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1	"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
EFA01862.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
EFA06004.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA07281.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EFA10303.2	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
EFA08129.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ97538.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
EFA09748.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA04827.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA04536.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB27308.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ98314.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA00606.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167238	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation"
EFA11877.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA05662.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EEZ97715.2	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
KYB28233.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA05528.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EEZ99846.2	1	MetaCyc: PWY-7379	"Mrna capping II"
EFA11279.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
EEZ99978.2	7	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
KYB26971.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
KYB29869.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EEZ99212.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EEZ97353.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
EFA03392.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA06978.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA00070.1	7	Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism"
KYB28764.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
EEZ99942.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
EFA06374.2	8	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
EFA08397.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
EEZ97395.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA05079.1	7	MetaCyc: PWY-7625;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226	"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI"
EEZ99703.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
EFA01663.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA05536.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
KYB26006.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
KYB26397.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
EFA07148.1	17	Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167238	"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation"
EEZ97742.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import"
EFA01634.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EEZ97870.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA07880.1	7	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-114608;Reactome: R-HSA-8957275	"G alpha (q) signalling events";"G alpha (i) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"Platelet degranulation";"Post-translational protein phosphorylation"
EFA00423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA08473.1	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
EFA08143.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB24713.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084	"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C"
KYB29642.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
EFA05606.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
EFA10219.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
EEZ97421.2	5	MetaCyc: PWY-6289;Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012	"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism"
EFA13273.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
EFA03675.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB27570.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
EFA04040.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
KYB25688.1	1	Reactome: R-HSA-211981	"Xenobiotics"
EFA04217.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
KYB29732.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-114508	"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis"
KYB26049.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA08613.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
KYB27583.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA13680.1	12	MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
KYB24968.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
KYB25288.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
EFA08820.2	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
EFA03300.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EFA00376.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA05248.1	31	MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-6282;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-5366;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-5147;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWYG-321;MetaCyc: PWY-5142;MetaCyc: PWY-6519;Reactome: R-HSA-199220;MetaCyc: PWY-7723	"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence"
EFA08615.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
KYB28734.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
KYB25464.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
EFA05539.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EFA11079.1	57	Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome"
KYB27221.1	18	MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism"
EFA02578.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
EFA13129.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
EFA01863.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA07553.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
KYB26857.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-110373	"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
KYB27680.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA03004.2	4	Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160	"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
EFA11083.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
KYB26427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB29413.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
EFA04316.2	6	MetaCyc: PWY-6952;MetaCyc: PWY-4261;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560	"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism"
EFA08638.2	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
EFA07894.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA05694.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
EFA03559.1	5	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events"
EFA08447.2	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
EFA05335.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA10111.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA03167.2	1	Reactome: R-HSA-912446	"Meiotic recombination"
EFA09569.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6	"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism"
EFA13430.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
EEZ97694.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EEZ99483.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EEZ98479.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
EFA02993.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
KYB25584.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EEZ98071.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA00947.2	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA00121.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA11424.2	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
EFA10481.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA01833.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
KYB28065.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
KYB28740.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889	"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes"
EFA06726.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA11234.1	5	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
EFA04028.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA03462.2	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
EFA06939.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA05374.1	10	MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-1042;Reactome: R-HSA-70263	"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis"
EFA03070.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
KXZ75916.1	13	MetaCyc: PWY-8052;Reactome: R-HSA-2871796;MetaCyc: PWY-6351;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039	"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis";"DAP12 signaling";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule"
EFA05804.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
KYB28460.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
EFA11572.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EEZ99315.1	6	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism"
EFA09029.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA05060.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741	"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
EFA13378.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA07282.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EFA04048.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EFA10183.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EEZ98115.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)"
EFA02324.2	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA04485.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA08658.1	6	Reactome: R-HSA-983168;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
EFA03333.2	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
EFA06035.2	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
EFA00569.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
EFA10110.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA07510.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
KYB25674.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
KYB25563.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
EFA00432.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-7117	"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
KYB26079.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
KYB25409.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
EFA04928.2	27	Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4085377	"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins"
EFA11878.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome"
EFA01244.2	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
KYB26669.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
EFA10709.2	14	MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-4302;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1	"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes"
EFA02202.1	13	Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1	"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes"
EFA10018.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EEZ97227.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling"
KYB25969.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
EFA06830.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EEZ99788.2	5	Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I"
KYB26274.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
EEZ97719.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
KYB27153.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
EEZ99805.2	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
EFA11416.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA05993.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3108214	"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins"
EFA07698.1	5	Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361	"Methionine salvage pathway";"Regulation of the apoptosome activity";"Formation of apoptosome";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
EEZ99316.1	6	KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23	"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism"
EFA05453.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EFA07026.1	5	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Heme biosynthesis"
EFA07554.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
EFA01850.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
EFA10323.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
EFA01900.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
KYB27808.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
EFA08116.2	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs"
KYB28908.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA05396.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EFA04314.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
KYB25985.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA09850.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EFA03198.1	15	Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-9665233;Reactome: R-HSA-9664565;Reactome: R-HSA-9665251;Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-9665249;Reactome: R-HSA-9665247;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795	"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling"
EFA04003.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
KYB27335.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261	"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I"
EFA11310.1	6	MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
EFA09167.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EFA06383.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-174437	"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand"
EEZ98405.2	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
EFA09795.1	14	MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
EEZ97452.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
EFA05671.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA02242.2	6	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling"
EFA01951.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA04833.1	25	Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-983189	"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"MHC class II antigen presentation";"Cilium Assembly";"Separation of Sister Chromatids";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins"
EFA08056.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA04092.2	13	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-1474244	"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"ECM proteoglycans";"Integrin cell surface interactions";"NCAM1 interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Extracellular matrix organization"
EFA03144.1	13	MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5392	"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II"
EEZ97678.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
EEZ98563.1	10	KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257	"Human cytomegalovirus infection";"Recycling pathway of L1";"mTOR signaling pathway";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"RSK activation"
EFA11529.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA02689.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA00806.2	9	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-191859	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"snRNP Assembly"
EEZ99615.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EFA13040.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
EFA12724.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
EFA03371.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
EFA02903.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
EFA06725.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA03761.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
EFA01430.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
EEZ99037.2	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
EEZ99507.1	7	MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1	"L-tyrosine biosynthesis IV";"Folate biosynthesis";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
EFA03686.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
EFA04762.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA08448.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB28375.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
EFA01829.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
KYB27902.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA00304.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
KYB27703.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB28707.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA02513.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
EFA10984.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ98905.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397	"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER"
EFA07537.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
EEZ97191.2	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
EEZ97366.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA09604.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB27523.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378	"G alpha (s) signalling events";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling"
EFA13496.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
EFA10056.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA02112.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA06562.1	7	KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7219	"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis"
EFA04528.1	7	MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255	"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)"
EEZ99676.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EFA04342.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081	"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling"
EFA00108.1	5	Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
EFA12161.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
KYB29411.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
KYB27138.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-189200	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Cellular hexose transport"
EFA05720.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
EFA06422.2	10	MetaCyc: PWY-3821;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
EFA07902.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
KYB29409.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
EFA01233.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
EEZ98503.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex"
KYB28529.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
KYB27775.1	7	Reactome: R-HSA-1483166;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485	"Synthesis of PA";"Choline biosynthesis III";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis"
EFA08835.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA05466.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
EFA11116.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EFA07025.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EEZ99784.2	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7409	"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Synthesis of PA";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
EFA03872.2	5	Reactome: R-HSA-983168;Reactome: R-HSA-5689877;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-977225	"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Amyloid fiber formation"
KYB26196.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
KYB26613.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA01082.1	8	MetaCyc: PWY-5740;MetaCyc: PWY-7573;MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739	"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis"
EFA08568.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
EEZ98004.1	14	MetaCyc: PWY-5076;MetaCyc: PWY-5057;MetaCyc: PWY-5101;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5104	"L-leucine degradation III";"L-valine degradation II";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis IV"
EEZ98819.2	7	Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-983170;Reactome: R-HSA-381033	"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Platelet degranulation";"PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones"
EFA07031.1	52	Reactome: R-HSA-1834949;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-73780;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167290;Reactome: R-HSA-167246	"Cytosolic sensors of pathogen-associated DNA";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Chain Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript"
EFA07356.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-975871	"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane"
EFA03490.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ99705.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
KYB28638.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EFA09253.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
KXZ75826.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA07388.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
KYB29621.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
EFA08699.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
EFA07171.1	19	MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-380270;Reactome: R-HSA-380320;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7197	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation"
EFA05917.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EFA12235.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA06519.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-162658;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-180534	"Regulation of RUNX3 expression and activity";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4"
EFA12118.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
KYB25902.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
EFA12114.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA04077.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA10433.2	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EFA01652.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
KYB28379.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
EFA07236.1	13	MetaCyc: PWY-2201;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3	"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"One carbon pool by folate";"L-histidine degradation III";"Folate polyglutamylation";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes"
KYB25844.1	1	Reactome: R-HSA-8951664	"Neddylation"
EEZ98191.1	11	Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-168138;KEGG: 04070+2.7.1.137;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-1632852;Reactome: R-HSA-1660517	"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Macroautophagy";"Synthesis of PIPs at the late endosome membrane"
EFA09866.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
EEZ99088.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling"
EFA02827.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA03072.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
KYB27599.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
EEZ98502.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EFA03680.2	3	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EFA05603.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA12946.2	1	Reactome: R-HSA-8949613	"Cristae formation"
EFA05514.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
EFA07493.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB26978.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
KYB26527.1	6	Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383	"MPS VII - Sly syndrome";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism"
EFA01913.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
EFA10388.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EFA05896.1	52	Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-73780;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-1834949;Reactome: R-HSA-72163;Reactome: R-HSA-5617472	"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Chain Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase I Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
EEZ98803.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EEZ99081.2	1	Reactome: R-HSA-1483255	"PI Metabolism"
EFA05339.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA06698.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
EFA10345.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
KYB27426.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA02050.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
EFA07572.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
KYB25476.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA09395.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA06721.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EEZ99578.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
EFA13035.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
KYB28722.1	1	Reactome: R-HSA-8951664	"Neddylation"
EEZ99004.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180534	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4"
EFA09042.2	7	Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214	"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs"
KYB28369.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
KYB24934.1	15	MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-6142	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
EFA10568.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
EFA04607.2	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
KYB25676.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
KYB25252.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
EFA09462.2	4	Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-879415	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling"
EFA10320.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
EFA11019.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Signaling by Hippo";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
EFA12886.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
KYB28463.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
KYB29477.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
EFA06561.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA00581.2	27	Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-191859	"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly"
EFA12804.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
KYB25190.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA04017.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EFA02100.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
KYB25738.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289	"Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation"
EEZ99502.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA10239.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
KYB26602.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state"
EFA07995.2	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
EEZ98188.2	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
EFA04630.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EFA02167.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA08991.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
EFA00780.2	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
KYB26001.1	52	Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-167238;Reactome: R-HSA-76066;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-1834949;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-72086	"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping"
EFA09869.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EFA05323.2	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
EFA06559.2	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
EFA05130.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA01836.2	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
EFA02554.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EFA11596.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB29603.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA09006.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
EFA08798.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323	"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling"
EFA07324.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA06469.1	33	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
EFA08935.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA12575.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I"
EFA08015.1	3	MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
KYB26590.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
KYB25941.1	15	MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-6142	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
EFA06279.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EEZ98051.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
EFA04161.2	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
EFA02105.1	30	KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-199418;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-392451;Reactome: R-HSA-9634638;Reactome: R-HSA-8948751;Reactome: R-HSA-6804758;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-8876198;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-69656;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-111447;Reactome: R-HSA-1358803;Reactome: R-HSA-5218920;Reactome: R-HSA-389513;Reactome: R-HSA-8941332;Reactome: R-HSA-211163;Reactome: R-HSA-6804759;Reactome: R-HSA-5628897	"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Negative regulation of the PI3K/AKT network";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"G beta:gamma signalling through PI3Kgamma";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Acetylation";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"RAB GEFs exchange GTP for GDP on RABs";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Cyclin A:Cdk2-associated events at S phase entry";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Cyclin E associated events during G1/S transition";"Activation of BAD and translocation to mitochondria";"Downregulation of ERBB2:ERBB3 signaling";"VEGFR2 mediated vascular permeability";"CTLA4 inhibitory signaling";"RUNX2 regulates genes involved in cell migration";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Metabolic Genes"
KYB25814.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176407	"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
KYB27349.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111459	"Formation of apoptosome";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage"
EFA08852.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
KYB25344.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
EEZ99220.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EFA08713.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
EFA04612.2	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
EEZ97594.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
KYB28090.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA09803.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA12734.1	4	KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26	"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
EEZ97866.2	31	MetaCyc: PWYG-321;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-6519;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-5147;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-8049;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388	"";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Pederin biosynthesis";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)"
EFA00102.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EEZ97800.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EFA09595.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
KYB26399.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EFA09537.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-168325	"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis"
KYB26038.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA01329.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB26414.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
KYB29328.1	5	MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
KYB25744.1	14	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
EFA06014.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA04753.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA00770.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA09340.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
EEZ98177.2	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
EFA12891.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Translesion Synthesis by POLH";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
EFA09160.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
EFA00701.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA11192.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EEZ99347.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EFA03728.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
KYB28361.1	5	MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
EFA08690.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
EFA10254.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA09711.2	29	Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-3371453;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Regulation of HSF1-mediated heat shock response";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
EFA06979.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
EFA13381.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
KYB26764.1	52	Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-174154	"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin"
KYB28630.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159227	"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA"
KYB29704.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-381426	"Chylomicron assembly";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"LDL clearance";"Chylomicron clearance";"VLDL assembly";"LDL remodeling";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
EFA12064.1	11	Reactome: R-HSA-432142;Reactome: R-HSA-391160;Reactome: R-HSA-512988;Reactome: R-HSA-210990;Reactome: R-HSA-114604;Reactome: R-HSA-389948;Reactome: R-HSA-9008059;Reactome: R-HSA-909733;Reactome: R-HSA-388841;Reactome: R-HSA-912694;Reactome: R-HSA-877312	"Platelet sensitization by LDL";"Signal regulatory protein family interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PECAM1 interactions";"GPVI-mediated activation cascade";"PD-1 signaling";"Interleukin-37 signaling";"Interferon alpha/beta signaling";"Costimulation by the CD28 family";"Regulation of IFNA signaling";"Regulation of IFNG signaling"
EFA13240.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29852.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
EFA08865.1	8	KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
KYB29837.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA07935.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
EFA07671.2	7	Reactome: R-HSA-69205;Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-1474151	"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
EFA08190.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
EEZ99262.2	4	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC";"Glycerophospholipid metabolism"
EFA06309.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
EFA11212.2	13	Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-112043	"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"PLC beta mediated events"
EEZ98826.2	4	Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
KYB26716.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
EFA03597.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EFA06298.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EFA08366.2	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
EFA05230.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EEZ98237.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
KYB29890.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
KYB28942.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
KYB27425.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
EEZ98538.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EFA11345.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA02331.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601	"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
KYB27813.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA09255.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
KYB29364.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746	"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein"
EFA11577.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EFA05868.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
EFA04570.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-68884	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Mitotic Telophase/Cytokinesis"
EFA04103.1	12	Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-193692	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR"
EFA01120.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB26215.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA03092.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
EFA08352.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EFA01230.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
EFA06841.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
EFA11746.1	1	Reactome: R-HSA-8949613	"Cristae formation"
EFA01735.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
EEZ97195.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
KYB29108.1	10	Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-447038	"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions"
EFA02756.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Polymerase switching";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
EEZ99208.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
KYB29211.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)"
KYB25475.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EEZ98192.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EFA02808.2	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
KYB27034.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA04299.1	11	MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)"
EFA03776.2	4	KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism"
EFA07686.2	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
EFA10333.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ97751.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EFA00686.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA09609.1	16	MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-1622;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6142	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
EEZ98853.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EFA00073.1	17	Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B"
EFA11047.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
KYB29656.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-1433557;Reactome: R-HSA-512988;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695;Reactome: R-HSA-194840;Reactome: R-HSA-9009391;Reactome: R-HSA-912526	"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"RET signaling";"G alpha (q) signalling events";"Signaling by SCF-KIT";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling";"Rho GTPase cycle";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling"
EFA09888.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ99477.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
KYB28818.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA10621.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
EFA12665.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EFA10605.2	12	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
KYB27466.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EFA11879.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EFA00352.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EEZ98535.2	12	Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-177929;Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-5362798;Reactome: R-HSA-75893;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-982772	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Signaling by EGFR";"Regulated proteolysis of p75NTR";"Collagen degradation";"Release of Hh-Np from the secreting cell";"TNF signaling";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Growth hormone receptor signaling"
EFA01113.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
EFA04392.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA07272.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
EFA02310.1	29	Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
EFA05865.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174184	"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
EFA02136.2	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
EEZ98592.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
EFA13272.2	15	Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5339716	"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin"
EFA02790.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EFA09206.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA12580.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA03762.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA07362.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EFA03759.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
EFA03560.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EEZ97197.1	4	Reactome: R-HSA-72731;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
EFA12612.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA11380.2	13	MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101	"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"CS/DS degradation"
KYB25657.1	10	KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-9639288;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Amino acids regulate mTORC1";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series"
EFA04902.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
KYB29003.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
KYB27092.1	3	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4;Reactome: R-HSA-6798163	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism";"Choline catabolism"
EFA05833.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-8939236	"Downstream TCR signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
KYB25398.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
KYB28546.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
KYB29089.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EFA09347.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA06380.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
KYB28165.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
KYB26178.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ98845.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
EFA06233.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
EFA12193.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I"
KYB27676.1	8	Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7391	"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)"
EFA10400.2	5	KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556	"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes"
EFA08461.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
EEZ99054.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
EFA03157.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689	"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex"
EFA01965.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA11202.1	16	KEGG: 00640+6.2.1.4;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-5690;MetaCyc: PWY-6728	"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Itaconate degradation";"TCA cycle II (plants and fungi)";"Methylaspartate cycle"
EFA06494.1	5	KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403	"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling"
KYB27612.1	7	MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway"
KYB29463.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
EFA06887.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
EFA02835.2	3	Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
EFA00372.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA00168.2	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
EFA00827.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
EFA00720.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
KYB26843.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EEZ97405.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EFA06839.2	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
EFA02661.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EEZ97797.2	9	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
EFA10490.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB28281.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
KYB26259.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA07156.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA06700.2	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport"
KYB26120.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
EFA05098.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
KYB26778.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KXZ75734.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
EEZ99326.2	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
KYB26547.1	1	Reactome: R-HSA-156588	"Glucuronidation"
KYB27499.1	1	Reactome: R-HSA-5676934	"Protein repair"
EFA05807.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
EEZ97169.2	9	Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-2871809	"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization"
EFA04600.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
KYB28774.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EEZ98404.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EFA00035.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
EFA04888.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis"
EFA01003.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones"
EFA01008.1	8	MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27	"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Glycolysis / Gluconeogenesis"
KYB29835.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA07164.1	10	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
EFA03370.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
EFA09218.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA06929.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation"
EEZ97849.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
KYB25112.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
KYB27259.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
EFA04284.1	56	Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-187577	"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21"
KYB29358.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-8051	"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I"
EEZ98642.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EFA00574.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA01372.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
KYB27009.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB29798.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
EFA10428.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA04156.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
EFA07389.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
EFA06889.2	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
KYB26059.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA02348.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
KYB25414.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA04291.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
EFA02851.1	33	Reactome: R-HSA-975110;Reactome: R-HSA-933541;Reactome: R-HSA-450302;Reactome: R-HSA-975144;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-975155;Reactome: R-HSA-5689880;Reactome: R-HSA-937039;Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-1257604;Reactome: R-HSA-975138;Reactome: R-HSA-933542;Reactome: R-HSA-937041;Reactome: R-HSA-975871;MetaCyc: PWY-7511;Reactome: R-HSA-166058;Reactome: R-HSA-6811558;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-205043;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-193692;Reactome: R-HSA-168927;Reactome: R-HSA-5689896;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-975163	"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated IRF7 activation";"activated TAK1 mediates p38 MAPK activation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"MyD88 dependent cascade initiated on endosome";"Ub-specific processing proteases";"IRAK1 recruits IKK complex";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"PIP3 activates AKT signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated NF-kB activation";"IKK complex recruitment mediated by RIP1";"MyD88 cascade initiated on plasma membrane";"Protein ubiquitination";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NRIF signals cell death from the nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulated proteolysis of p75NTR";"TICAM1, RIP1-mediated IKK complex recruitment";"Ovarian tumor domain proteases";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
EFA07821.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA09896.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA11290.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
EFA04252.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
EFA07350.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA01222.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA06474.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA10788.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
KYB26631.1	10	KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977	"Galactose metabolism";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
EFA11443.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA00691.2	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
KYB28074.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
EEZ98120.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
KYB26671.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination"
KYB29838.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29047.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
EFA07663.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
KYB25864.1	23	Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-418217	"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"G alpha (z) signalling events";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta"
KYB27535.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA07116.1	1	Reactome: R-HSA-74217	"Purine salvage"
KYB27211.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ97861.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
EFA06670.2	10	KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-5609977	"Galactose metabolism";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
KYB27619.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events"
KYB27228.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
KYB28517.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation"
KYB25044.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes"
EFA06699.2	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
EFA08474.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
EFA01051.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EFA05204.2	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-5147;Reactome: R-HSA-75105;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-4381;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-7663;MetaCyc: PWY-5366;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012	"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis"
EFA08847.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling"
EFA01122.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EEZ98825.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA03670.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
KYB29695.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA07284.1	12	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
EFA06626.2	1	Reactome: R-HSA-8951664	"Neddylation"
EFA00152.1	24	KEGG: 04926+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-9634635	"Relaxin signaling pathway";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Integrin signaling";"RSK activation";"VEGFR2 mediated cell proliferation";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ"
EFA01741.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
EFA10650.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
KYB27419.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
EFA10002.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EFA02558.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EFA04120.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
EFA11812.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism"
EEZ97482.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
EFA04363.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
KYB26512.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
EFA05976.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
EFA05195.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EFA07996.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-113501	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
EFA04919.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
EFA04105.2	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
EEZ98964.2	1	Reactome: R-HSA-1483191	"Synthesis of PC"
EFA02515.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
EFA07756.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB27802.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
KYB27245.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
EFA08906.2	10	MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2	"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism"
EFA06019.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Protein ubiquitination"
EEZ97228.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA07230.2	7	Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084	"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
KYB27853.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
EFA00464.1	1	Reactome: R-HSA-8951664	"Neddylation"
KYB28627.1	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
EFA06443.1	3	KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
EFA09930.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EFA07823.1	33	Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-5663220	"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"RHO GTPases Activate Formins"
KYB26425.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
KYB25306.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA01284.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
EFA00566.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
EFA02177.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117	"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis"
EFA09313.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism"
EFA07343.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA01282.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA01129.2	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
EFA10166.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
EFA07480.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB27055.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
KYB26419.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
EEZ99023.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
KXZ75551.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EFA12234.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic"
KYB26873.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA05373.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
EFA08664.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
EFA08765.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
KYB28459.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EFA08119.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
EFA11214.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EFA10103.2	1	Reactome: R-HSA-156588	"Glucuronidation"
EEZ99558.2	11	Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
EEZ98594.1	17	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6	"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes"
KYB25108.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA10974.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
EEZ99348.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-5617833	"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Gap junction assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Cilium Assembly"
EFA06812.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
KYB25018.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EFA09518.2	56	Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation"
EFA07503.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EFA04002.2	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
EFA02997.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
KYB26045.1	1	Reactome: R-HSA-8964038	"LDL clearance"
EFA02267.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
EEZ97388.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
KYB28650.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA00049.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
KYB27086.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB28980.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA10600.1	3	MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
EFA06063.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
KYB24696.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
EFA01492.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB26511.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
EFA03940.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA09605.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
EFA02441.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EFA03390.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
EFA09496.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
EFA05375.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA09251.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA04619.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA06663.1	24	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Separation of Sister Chromatids";"Cilium Assembly";"Mitotic Prometaphase";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
EFA01517.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
EFA06310.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
EFA10998.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA02147.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB28470.1	52	Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-1834949;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-5578749	"Estrogen-dependent gene expression";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"Cytosolic sensors of pathogen-associated DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs"
EEZ97756.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA12397.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EEZ97659.2	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-7282	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
EFA10154.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
EEZ99783.2	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA11292.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Separation of Sister Chromatids";"Cilium Assembly";"MHC class II antigen presentation";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Kinesins";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy"
EFA06593.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA08098.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EFA10685.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EFA09469.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
EFA01887.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
EFA11790.2	9	MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
EFA06046.2	2	Reactome: R-HSA-432722;MetaCyc: PWY-7942	"Golgi Associated Vesicle Biogenesis";"5-oxo-L-proline metabolism"
EFA11114.1	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
KYB26430.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EFA09019.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
EFA06495.2	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043	"Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis"
KYB25697.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA00587.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EFA09904.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
KYB29131.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
EFA07406.1	6	Reactome: R-HSA-2029485;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-1250196;Reactome: R-HSA-1489509	"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling"
EFA02038.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
KYB25901.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA01848.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
KYB29542.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
KYB29332.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB27934.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
KYB28975.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
EFA02804.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
EFA05251.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EFA02232.2	1	Reactome: R-HSA-373753	"Nephrin family interactions"
KYB28976.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
EFA09724.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
KYB25410.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
EFA04274.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
EFA05847.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
EFA07131.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
EEZ97252.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
KYB28119.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
EFA05249.2	31	MetaCyc: PWY-7663;MetaCyc: PWY-5366;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-5989;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;MetaCyc: PWY-6282;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-8047;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWYG-321;MetaCyc: PWY-7858;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;Reactome: R-HSA-75105	"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"";"(5Z)-dodecenoate biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis"
KYB29169.1	6	MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
EFA06327.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
EFA06295.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EFA07446.2	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
KYB29048.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
EFA01238.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
EFA04649.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA12923.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA06281.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
EEZ98096.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EFA02315.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA09715.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade"
EEZ99689.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
EFA04812.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA12963.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KYB25597.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
EEZ97799.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
EFA02681.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
EFA05892.1	2	KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19	"Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism"
EEZ97355.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
EFA12146.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
KYB27111.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerolipid metabolism"
KYB26048.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA12217.1	6	MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)"
KYB27188.1	13	Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Signaling by PDGF";"NCAM1 interactions";"Integrin cell surface interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Collagen degradation";"Collagen chain trimerization";"Extracellular matrix organization";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
EFA01286.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090	"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Collagen degradation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures"
EFA08377.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
KYB25715.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
KYB29658.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EFA00170.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
EFA11312.2	1	Reactome: R-HSA-525793	"Myogenesis"
EFA08645.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
EFA02321.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones"
KYB26081.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EFA02054.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
KYB29177.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EFA06320.2	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
KYB27164.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EFA08782.2	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
EEZ97621.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA09203.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA06308.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
EFA03667.1	1	Reactome: R-HSA-419771	"Opsins"
KYB27658.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
EFA11530.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7854	"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
EFA12878.2	1	Reactome: R-HSA-8951664	"Neddylation"
KYB29821.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
EEZ97931.1	8	KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Galactose metabolism"
EFA06092.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA12961.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EEZ97693.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EFA02222.2	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
EFA12096.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
EFA00283.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
EFA03902.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA09757.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
KYB29228.1	12	Reactome: R-HSA-982772;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-1442490;Reactome: R-HSA-193692;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606	"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Release of Hh-Np from the secreting cell";"Collagen degradation";"Regulated proteolysis of p75NTR";"Signaling by EGFR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
EFA08802.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
KXZ75832.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
EEZ97424.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
EFA03199.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
EFA00308.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
EEZ98092.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
EFA07994.1	4	KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834	"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Spermidine biosynthesis III"
KYB28389.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
EFA00171.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation"
KYB27078.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862	"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
KYB26848.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
EFA06481.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
EFA00178.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EEZ98830.1	6	MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis"
EFA06434.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
EFA04231.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-8853884	"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX"
KYB29693.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
EFA10214.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
EEZ97941.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA07675.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
KYB26194.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
KYB25176.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EFA00721.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA09802.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA02556.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA10733.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EFA00397.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-112382	"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex"
EEZ99905.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
EFA03396.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
KYB29839.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29297.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EFA02834.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
KYB28116.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
KYB26838.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock"
EFA05346.2	5	Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955	"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
KYB26528.1	12	MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292	"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"MPS VII - Sly syndrome"
KYB29060.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
EFA11218.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
KYB29665.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA08605.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA07189.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EFA03659.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
EFA07178.2	11	Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862	"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
EFA00333.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
KYB29810.1	2	Reactome: R-HSA-189200;Reactome: R-HSA-435368	"Cellular hexose transport";"Zinc efflux and compartmentalization by the SLC30 family"
EFA08278.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
EFA06120.1	6	Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211	"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling"
KYB25772.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA06748.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA08827.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA07193.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
KYB27779.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
KYB27855.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA05446.1	18	Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167243	"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery"
EEZ98562.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
KYB27628.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
EEZ99831.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA02601.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
KYB29417.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EFA11744.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation"
EFA05733.1	17	MetaCyc: PWY-6398;KEGG: 00232+1.14.14.1;KEGG: 00380+1.14.14.1;KEGG: 00590+1.14.14.1;KEGG: 00591+1.14.14.1;MetaCyc: PWY-6992;Reactome: R-HSA-211981;KEGG: 00140+1.14.14.1;KEGG: 00982+1.14.14.1;MetaCyc: PWY-7466;MetaCyc: PWY-5451;KEGG: 00980+1.14.14.1;KEGG: 00071+1.14.14.1;MetaCyc: PWY-7826;MetaCyc: PWY-5665;KEGG: 00627+1.14.14.1;KEGG: 00830+1.14.14.1	"Melatonin degradation I";"Caffeine metabolism";"Tryptophan metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"1,5-anhydrofructose degradation";"Xenobiotics";"Steroid hormone biosynthesis";"Drug metabolism - cytochrome P450";"Acetone degradation III (to propane-1,2-diol)";"Acetone degradation I (to methylglyoxal)";"Metabolism of xenobiotics by cytochrome P450";"Fatty acid degradation";"Amaryllidacea alkaloids biosynthesis";"Vanillin biosynthesis I";"Aminobenzoate degradation";"Retinol metabolism"
KXZ75899.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-110373	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
EEZ97345.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange"
EFA04921.1	4	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
EFA10118.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA10929.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EFA10717.1	8	KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Photosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
EEZ98805.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA12319.2	13	Reactome: R-HSA-202433;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2029485	"Generation of second messenger molecules";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis"
EEZ97509.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
EFA09345.2	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
EFA11368.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA09995.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"RHO GTPases Activate Formins"
EFA13575.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
EFA04319.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
EFA05273.2	4	Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling"
EFA10130.2	7	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6724	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation V";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation II"
EFA10435.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
KYB26690.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
EFA10462.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EFA03165.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
KYB26349.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
EFA11381.2	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
EFA01590.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EFA08198.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
KYB28887.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
KYB25152.1	32	Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-72165	"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway"
EEZ97485.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
EFA03505.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EFA01592.2	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
EFA02270.2	8	Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis"
EFA09129.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EFA05246.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
KYB28383.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
EFA06251.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EFA05368.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
KYB25721.1	17	Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-69091	"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching"
KYB24820.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EFA05491.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EEZ98712.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA04846.1	4	Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4717374	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
EFA03729.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EFA10675.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ99809.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EFA11148.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EEZ97827.2	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
EFA10488.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
EFA03811.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
KYB26391.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA02004.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897	"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes"
EFA04526.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB25189.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
EFA02415.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
KYB27756.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA07231.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA08342.2	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
EFA05473.2	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
EFA07961.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EEZ98764.2	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
KYB26000.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5628897	"Estrogen-dependent gene expression";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes"
EEZ99359.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EFA06784.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
EFA06719.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA08618.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-182218	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Ion channel transport";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation"
KYB29730.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EFA00388.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA06854.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-933541	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation"
EFA11006.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EFA12799.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EEZ98124.2	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
EEZ99828.2	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
EEZ97239.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EFA11687.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
EFA04948.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
KYB28295.1	10	Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;MetaCyc: PWY-7394;Reactome: R-HSA-975634	"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Purine metabolism";"Retinoid cycle disease events";"Urate conversion to allantoin III";"Amyloid fiber formation";"Neutrophil degranulation";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Retinoid metabolism and transport"
EFA04060.1	3	Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12	"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism"
EFA05672.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA11294.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
KXZ75736.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
EFA07881.1	7	Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-140837;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"G alpha (i) signalling events"
EFA11365.1	31	MetaCyc: PWY-7663;MetaCyc: PWY-5366;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-8049;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-6519;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWYG-321;MetaCyc: PWY-7858;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-5147	"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Pederin biosynthesis";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)"
EFA10684.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EFA01283.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
KYB24996.1	7	Reactome: R-HSA-5693571;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
EEZ99725.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
EFA09634.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
EFA07529.2	1	Reactome: R-HSA-3295583	"TRP channels"
EEZ98485.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EFA07775.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
EFA13218.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-174084	"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C"
EFA08649.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EFA10574.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
KXZ75649.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EFA10955.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
EFA05409.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
EFA05182.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA07169.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EFA13662.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
KYB25736.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
KYB28465.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
KYB27184.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
KYB25589.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA09124.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA10127.2	5	MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
EFA08691.1	18	MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Synthesis of PA"
EFA00437.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
EFA05239.1	5	KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688	"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism"
EFA09449.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
EFA00407.2	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
KYB25634.1	2	Reactome: R-HSA-211981;Reactome: R-HSA-211999	"Xenobiotics";"CYP2E1 reactions"
EFA07850.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
KYB28064.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
KYB26566.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EFA03058.1	8	Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of RAC1";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
EFA13005.2	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EFA11358.1	3	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH"
EFA10821.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA02347.1	1	Reactome: R-HSA-8951664	"Neddylation"
KYB27212.1	18	KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00960+2.6.1.1	"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis"
KYB27333.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
EFA10391.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
KYB28924.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
EFA10810.2	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EFA07367.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
KYB26466.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
EFA03586.1	6	MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-196780	"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism"
EFA00463.1	1	Reactome: R-HSA-8951664	"Neddylation"
KYB26189.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
KYB28152.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA00672.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
EFA09217.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EFA01543.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
KYB28881.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
EFA04074.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
KYB27862.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
KYB25762.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
KYB28528.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
EFA09483.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I"
KYB24843.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
EFA11030.1	6	Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
EEZ99469.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-432040	"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins"
KYB27643.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
EFA09572.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
EFA01289.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490	"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation"
EFA07387.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
KYB27370.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
EFA07487.1	17	Reactome: R-HSA-3270619;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"IRF3-mediated induction of type I IFN";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
KYB28736.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EFA12366.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EFA02157.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
KYB25930.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
KYB28284.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
EFA10439.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
KYB26654.1	5	MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22	"Stachyose degradation";"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
EFA07407.1	6	Reactome: R-HSA-1489509;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"DAG and IP3 signaling";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
KYB27642.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
EFA13677.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
EFA00676.2	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
KYB26929.1	25	Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736	"Kinesins";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors"
EFA01854.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B"
EFA12149.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
KYB29856.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
KYB25395.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EFA01132.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
KYB24949.1	9	Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5218920	"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability"
EFA09975.1	10	MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I"
EFA06492.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
EFA03065.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
KYB29507.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB26305.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EFA04890.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EFA07957.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA07157.1	1	Reactome: R-HSA-156588	"Glucuronidation"
KYB28558.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
EFA08842.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40	"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism"
EFA06399.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA03052.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
EFA10321.2	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
EFA11061.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I"
EFA01723.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
EFA01968.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EFA03020.2	14	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)"
EEZ97187.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
EFA04575.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EFA01124.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
EFA00945.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
EFA00920.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA12722.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"MAP2K and MAPK activation";"Neutrophil degranulation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
EFA01593.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
EFA02034.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903	"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy"
EFA10063.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
EEZ99465.2	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
EFA07030.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
KYB27316.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475	"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis"
EFA12261.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
EFA04065.1	5	Reactome: R-HSA-917937;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664	"Iron uptake and transport";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Neddylation"
KYB27099.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA11313.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA09052.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EFA06407.2	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
EFA02847.1	30	Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-195253	"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Neddylation";"Iron uptake and transport";"Vpu mediated degradation of CD4";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex"
KYB26108.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA06729.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
EFA08457.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
EFA11039.2	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
KYB29133.1	9	Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7902;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94	"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
EFA07836.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
EFA08558.1	11	Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340	"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation"
EFA04170.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
KYB29178.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
KYB26173.1	13	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions"
EFA06850.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EFA07261.2	52	Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling"
EFA07177.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA02605.2	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EFA04061.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes"
KYB26258.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
EFA00547.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA05810.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
KYB27721.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
EFA09978.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
KYB25899.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
EFA09906.2	28	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK"
EFA08916.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-110314	"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Polymerase switching";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex"
KYB26439.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA09559.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
KYB29174.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
EFA09262.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
EEZ97734.1	9	Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535	"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer"
EFA00120.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
KYB27717.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
EEZ97852.2	10	Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-201688	"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Synthesis of PC";"WNT mediated activation of DVL"
EFA08204.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EEZ98133.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
KYB29705.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938	"Platelet sensitization by LDL";"Chylomicron remodeling";"Scavenging by Class F Receptors";"VLDL clearance";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"LDL remodeling";"LDL clearance";"Chylomicron clearance";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand"
KYB28432.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
EFA10294.2	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
EFA11905.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
EEZ98161.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA10680.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
EFA06030.2	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
EEZ98997.2	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
EFA02178.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EEZ97812.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
KYB26086.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
KYB28301.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA06292.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB27445.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
KYB27242.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EFA04916.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EFA11379.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EEZ97282.2	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER"
KYB28664.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
EFA11346.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
EEZ97360.2	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
KYB28799.1	6	Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017	"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Neutrophil degranulation";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
KYB25675.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
EFA10112.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA09539.1	11	MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;Reactome: R-HSA-71403	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)"
EFA11562.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA01142.2	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
KYB25555.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359	"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation"
KYB27720.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
KYB25719.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB29097.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
EEZ99218.2	1	Reactome: R-HSA-390696	"Adrenoceptors"
EEZ99525.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
KYB26195.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
KYB26451.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ97311.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis"
EFA04346.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EEZ98484.1	9	MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
KYB27467.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EFA13254.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
KYB28656.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EFA07316.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
EFA09949.2	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
EFA08318.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
KYB27012.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB26070.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB27037.1	1	Reactome: R-HSA-211981	"Xenobiotics"
EFA01361.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-1268020;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105	"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Mitochondrial protein import";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport"
KYB25942.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EFA03106.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
EFA01500.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA02434.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"G0 and Early G1"
KYB25898.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
EFA01870.2	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
EEZ98185.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978	"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)"
EFA08170.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
EFA08624.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
EFA06039.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EEZ97330.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA00549.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
EEZ97295.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA04519.2	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
EFA05170.2	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
KYB29475.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
EFA06480.1	5	KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
EFA02859.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EFA05578.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
EFA09680.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA00987.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA00031.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
EFA02771.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA05357.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
EFA13034.1	9	Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-7442	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis"
EFA10792.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
EFA02325.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
EFA02633.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
KYB28422.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
EFA06459.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
EFA00505.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
EFA07576.2	9	Reactome: R-HSA-3642279;Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790	"TGFBR2 MSI Frameshift Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer"
KYB25932.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EFA11417.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EFA12889.2	6	Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-73930	"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
EFA10997.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
EFA03141.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
EFA06896.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
KYB29722.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EFA02416.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
KYB25711.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
EFA08946.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
EFA06446.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
EFA10312.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
EFA04253.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
EEZ97850.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
EEZ99482.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EEZ97358.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EEZ97848.1	9	MetaCyc: PWY-6964;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-381;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2	"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism"
KYB25576.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
EFA02443.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
KYB25955.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
EFA12063.2	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
EFA04064.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EFA00424.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB26202.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA08415.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EEZ98701.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EEZ98196.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
EEZ97697.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EFA03366.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
EFA05404.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
EFA05744.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
KYB28595.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340	"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"snRNP Assembly";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation"
EFA03250.2	17	MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-6644;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-6608	"Guanine and guanosine salvage";"Purine metabolism";"Pyrimidine metabolism";"Purine catabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III"
EFA03003.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
EFA08801.2	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
EFA05871.2	57	Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Degradation of DVL";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis"
EFA09610.1	16	MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-1042;MetaCyc: PWY-5723;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-7218	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
EFA01483.2	1	Reactome: R-HSA-8951664	"Neddylation"
EFA03097.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
KYB26618.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
EFA06253.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-9018519	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Estrogen-dependent gene expression"
EFA11241.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
EFA12610.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EFA13608.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EFA04962.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EFA10817.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
KYB29057.1	5	Reactome: R-HSA-5368286;Reactome: R-HSA-9033241;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-8866654	"Mitochondrial translation initiation";"Peroxisomal protein import";"Mitochondrial translation elongation";"Mitochondrial translation termination";"E3 ubiquitin ligases ubiquitinate target proteins"
KYB27031.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EFA02898.2	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
EEZ97363.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
EFA08934.1	1	Reactome: R-HSA-1296061	"HCN channels"
KYB28092.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA07463.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB28836.1	8	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
KYB29462.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
EFA11531.2	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
KYB25250.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
KYB29165.1	1	Reactome: R-HSA-446193	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
KYB26470.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
EFA00823.2	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
EFA07528.2	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
EFA00083.2	14	MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5080;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs"
EFA11193.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation"
EFA04382.1	60	MetaCyc: PWY-7401;KEGG: 00380+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-5138;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6863;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00930+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7779;Reactome: R-HSA-77350;KEGG: 00362+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;Reactome: R-HSA-1482798;Reactome: R-HSA-77348;MetaCyc: PWY-6883;MetaCyc: PWY-7007;Reactome: R-HSA-77346;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7778;Reactome: R-HSA-77305;KEGG: 00310+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00280+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;KEGG: 00281+4.2.1.17;Reactome: R-HSA-77285;Reactome: R-HSA-77310;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-5136	"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Tryptophan metabolism";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Fatty acid elongation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Valine, leucine and isoleucine degradation";"Fermentation to 2-methylbutanoate";"Caprolactam degradation";"Androstenedione degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Phenylalanine metabolism";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"Methyl tert-butyl ether degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Benzoate degradation";"Aminobenzoate degradation";"Fatty acid salvage";"Acyl chain remodeling of CL";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Pyruvate fermentation to butanol II (engineered)";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Glutaryl-coa degradation";"2-methylpropene degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Lysine degradation";"Butanoate metabolism";"Fatty acid elongation";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Tryptophan metabolism";"Butanoate metabolism";"beta-Alanine metabolism";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Geraniol degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Benzoate degradation";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Lysine degradation";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)"
KYB28956.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB28880.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
KYB25639.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
EFA03763.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EFA05857.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EFA06966.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
KYB29135.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA05143.1	22	MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7727;Reactome: R-HSA-75876;MetaCyc: PWY-5353;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7606;MetaCyc: PWY-7053	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)"
EFA10643.2	14	MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
EFA12180.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
KYB27385.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EEZ97487.2	12	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic"
EFA09707.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
KYB25020.1	7	KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism"
KXZ75837.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
KYB27971.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA00066.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB26881.1	1	Reactome: R-HSA-8951664	"Neddylation"
EFA08449.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
EFA10037.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
KYB24943.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-5083630	"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3"
EFA10857.2	5	Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;MetaCyc: PWY-5381	"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)"
EFA06449.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
KYB26668.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
EFA12797.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA13033.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response"
KYB27563.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
EFA11876.2	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA"
EFA09994.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
KYB28954.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
KYB25473.1	1	Reactome: R-HSA-156588	"Glucuronidation"
EFA02989.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EEZ99723.1	10	KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;MetaCyc: PWY-5691;Reactome: R-HSA-977225;MetaCyc: PWY-7394;Reactome: R-HSA-975634	"Purine metabolism";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Neutrophil degranulation";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Amyloid fiber formation";"Urate conversion to allantoin II";"Retinoid metabolism and transport"
KYB26842.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA04992.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EFA02207.2	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
EFA06668.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
EEZ98800.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
KYB27378.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EFA12663.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
EEZ98695.2	27	Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231	"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript"
KYB28792.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events"
EFA05162.2	8	Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689	"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex"
EFA02268.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EFA10421.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
KYB26619.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
KYB26384.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
KYB29586.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
KYB28833.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
EFA01748.1	10	MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis"
EEZ98621.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
EFA08168.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
EFA06296.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
EFA12412.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
KYB24936.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
EEZ98095.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
KYB28557.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
EFA02192.2	5	Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism"
EFA06118.2	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
EFA06843.2	4	Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-379716	"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation"
EFA05509.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
KYB29729.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
EFA05867.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
EFA04770.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
KYB27139.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA03044.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EFA04567.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EEZ99317.2	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
EFA09438.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EFA10548.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EFA10968.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
EFA13305.2	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
KYB29198.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
EFA11426.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
KYB27860.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA08786.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EFA01604.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EFA04592.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
EFA11745.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
KYB25512.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EEZ99710.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
EFA10326.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
KYB28089.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EFA00963.1	14	KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-499943;KEGG: 00980+2.5.1.18;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1	"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Interconversion of nucleotide di- and triphosphates";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate and aldarate metabolism";"Glutathione metabolism"
EEZ98476.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
EEZ98394.2	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
EFA07448.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
EFA10197.1	11	MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-5154;Reactome: R-HSA-500753	"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis"
EFA01079.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
EFA10454.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
KYB29718.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EFA11619.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EFA09688.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
EFA09524.2	56	Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-1169091	"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells"
EFA07302.1	29	Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167152	"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat"
EFA13206.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
EFA06520.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
KYB27618.1	25	Reactome: R-HSA-8939256;Reactome: R-HSA-8941858;Reactome: R-HSA-8935964;Reactome: R-HSA-8878166;Reactome: R-HSA-8941284;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-8939246;Reactome: R-HSA-8877330;Reactome: R-HSA-8940973;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245;Reactome: R-HSA-8951936;Reactome: R-HSA-8939247;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-8941332;Reactome: R-HSA-8939236;Reactome: R-HSA-8949275;Reactome: R-HSA-8941333;Reactome: R-HSA-8941326	"RUNX1 regulates transcription of genes involved in WNT signaling";"Regulation of RUNX3 expression and activity";"RUNX1 regulates expression of components of tight junctions";"Transcriptional regulation by RUNX2";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates bone development"
KYB26074.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EFA12725.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
KYB26774.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
KYB29412.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
EFA03151.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
KYB26214.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-7233	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
EFA04011.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
EFA12034.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EFA02013.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EFA03145.1	7	MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-46;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;Reactome: R-HSA-70635	"Canavanine degradation";"Arginine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Urea cycle"
EEZ99016.2	15	MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
EFA01279.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
KYB29719.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EFA03754.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
KYB29272.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state"
EFA00708.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
KYB29418.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EEZ97825.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EFA01818.1	5	KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527	"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation"
KYB27925.1	9	MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351	"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
EFA01002.1	4	KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030	"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
EFA04087.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
EFA10325.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
EFA09658.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
KYB25775.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EFA12165.2	3	Reactome: R-HSA-383280;Reactome: R-HSA-983231;Reactome: R-HSA-8939236	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
KYB26165.1	17	MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7205	"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation"
EFA04644.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EFA05209.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EFA04973.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
EFA08230.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EFA07884.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EFA09893.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
KYB25129.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EFA11550.2	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
EEZ97354.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
EFA10123.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
EFA00260.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EEZ98181.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
KYB24970.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EFA09410.1	8	Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6783310	"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Fanconi Anemia Pathway"
EEZ98809.1	6	KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1622	"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)"
KYB25776.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EEZ97589.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EFA02978.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EFA05173.2	10	MetaCyc: PWY-5895;MetaCyc: PWY-5890;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-5891;MetaCyc: PWY-5849	"Menaquinol-13 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-6 biosynthesis"
EFA06967.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
EFA09968.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"