Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_044268779.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044264117.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859	"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly"
XP_044260585.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044270267.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1	"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism"
XP_044260881.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_044261832.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815	"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D"
XP_044261977.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044257488.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044265379.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_044270362.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_044253230.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044253405.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044261570.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044253137.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA"
XP_044253353.1	12	KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;KEGG: 00620+2.3.3.9;MetaCyc: PWY-5744;MetaCyc: PWY-5749;MetaCyc: PWY-6969;MetaCyc: PWY-7854;MetaCyc: PWY-7294;MetaCyc: PWY-6728;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7295;MetaCyc: PWY-7118	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate assimilation";"Itaconate degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"D-xylose degradation IV";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"L-arabinose degradation IV";"Chitin degradation to ethanol"
XP_044265748.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044258229.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044257786.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044271742.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044256936.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044258974.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_044257943.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044258887.1	4	KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_044257956.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044269161.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044261702.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion"
XP_044266543.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_044267255.1	12	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism"
XP_044257004.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_044262573.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044265004.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition"
XP_044262446.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-983168	"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044265925.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044262416.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_044268164.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044256862.1	4	Reactome: R-HSA-6807047;MetaCyc: PWY-8026;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis"
XP_044261356.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_044261066.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer"
XP_044266799.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044252518.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044257468.1	5	Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221	"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway"
XP_044258139.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_044253389.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044271912.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_044254705.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044252603.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_044265744.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044263174.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044262316.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_044254364.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044261348.1	6	Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_044263317.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044269254.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_044262746.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_044268192.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044257696.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044256360.1	10	KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11	"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
XP_044258149.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044271911.1	4	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_044260765.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_044257398.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044268241.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044266884.1	9	MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52	"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_044254336.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044266445.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763	"Nephrin family interactions";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction"
XP_044259498.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_044265929.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044263179.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044268909.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_044266453.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044258169.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775	"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Ion homeostasis"
XP_044259814.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044263977.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044257005.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_044261177.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044269856.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972	"Thermogenesis";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_044262747.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044257029.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_044256786.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_044257808.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044256702.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_044261425.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_044270976.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_044261573.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044267417.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_044252995.1	12	MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_044271790.1	4	KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_044262797.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_044255224.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_044261791.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_044254086.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044261577.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_044252795.1	10	KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5497	"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)"
XP_044263256.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044260183.1	4	MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_044267837.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_044261683.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_044259307.1	10	KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_044252752.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580	"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_044259151.1	10	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-437239	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Recycling pathway of L1"
XP_044266302.1	9	KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5	"Phenylalanine metabolism";"Novobiocin biosynthesis";"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis"
XP_044263651.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044260790.1	5	Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946	"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants"
XP_044270768.1	6	KEGG: 00562+2.7.1.150;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.150;MetaCyc: PWY-6352	"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis"
XP_044259173.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044263946.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_044256143.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic"
XP_044272630.1	6	Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795	"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling"
XP_044263438.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_044254695.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044263713.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044261526.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044270907.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044271905.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453	"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis"
XP_044261675.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257243.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_044270146.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_044259422.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_044269048.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972	"Neutrophil degranulation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"mTOR signalling";"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_044269381.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_044257042.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_044267796.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_044266316.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044261935.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7587	"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
XP_044262592.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP"
XP_044270472.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044257535.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044263358.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044264172.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044253018.1	5	MetaCyc: PWY-7185;MetaCyc: PWY-7210;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6	"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"Pyrimidine metabolism";"Purine metabolism"
XP_044268777.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_044266377.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044263866.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556	"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Neddylation";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport"
XP_044254362.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044260944.1	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism"
XP_044260680.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_044259581.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044257456.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_044260477.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159230	"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA"
XP_044268604.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044264917.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044255826.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044272756.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044265608.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044271278.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_044269232.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044265877.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044258003.1	9	MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94	"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_044262240.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_044254854.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044270405.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044259623.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_044260702.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044256265.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044256641.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_044266139.1	13	Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320	"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"ECM proteoglycans";"Collagen degradation";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Signaling by PDGF";"Extracellular matrix organization";"Laminin interactions";"Anchoring fibril formation"
XP_044258429.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_044271736.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044254683.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044253932.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_044269072.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_044268521.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_044255223.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_044252723.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044265054.1	5	Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168	"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)"
XP_044268608.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044270900.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044254159.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044263621.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-432040	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_044270997.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044257161.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044265288.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044266515.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044267341.1	12	MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_044272466.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_044265430.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_044268001.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;MetaCyc: PWY-7250	"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_044263435.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044263972.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044264969.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044270382.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044258792.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044259608.1	4	KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755583	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_044267911.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_044257633.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging"
XP_044261031.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_044270729.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_044261980.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044267925.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-975957	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044261102.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044265675.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044269398.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044271719.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044266533.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_044272326.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-77288;MetaCyc: PWY-7094;Reactome: R-HSA-77346;KEGG: 00280+1.3.8.7;Reactome: R-HSA-77348;KEGG: 00071+1.3.8.7	"PPARA activates gene expression";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid salvage";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Valine, leucine and isoleucine degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid degradation"
XP_044258430.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_044254815.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044269702.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044264080.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_044259115.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044253443.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090	"Collagen degradation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures"
XP_044265742.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_044260332.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_044259746.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_044268547.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044261227.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044253720.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044260982.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044257537.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044257650.1	13	KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Ethanol oxidation";"Pyruvate metabolism";"Propanoate metabolism"
XP_044257764.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044264923.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_044253857.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044259883.1	4	MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_044265191.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044259408.1	8	MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism"
XP_044265116.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044265751.1	15	Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6807505	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes"
XP_044262270.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044253943.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_044262429.1	17	KEGG: 00020+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383	"Citrate cycle (TCA cycle)";"Methane metabolism";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_044271737.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044271529.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044265708.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_044253701.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_044260569.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044261681.1	12	Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-193692	"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Regulated proteolysis of p75NTR"
XP_044252941.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044255941.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044271421.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044260406.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044253436.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044256459.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044268840.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181	"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB"
XP_044261937.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044258376.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044255966.1	8	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination"
XP_044254037.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_044259001.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044265579.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_044265674.1	5	KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_044259989.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044265892.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044268927.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_044257593.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_044267402.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_044263896.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044272229.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044269123.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044258060.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044268373.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044262431.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_044263766.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_044266065.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_044264175.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_044272515.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257086.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044269562.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044258305.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_044270996.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044252888.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044266072.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044253827.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines"
XP_044256113.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985	"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose"
XP_044272564.1	17	MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_044261499.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044265041.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-6859;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659	"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis"
XP_044266665.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_044265991.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044254289.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044269151.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044255972.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044261416.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044254046.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_044263634.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044269491.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_044261495.1	57	Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764	"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling"
XP_044270746.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_044254751.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition"
XP_044270908.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044263418.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044258368.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_044269255.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_044266337.1	7	MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_044270176.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044266429.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044260777.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_044267550.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_044266672.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044269367.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044252652.1	14	MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1	"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Photorespiration ";"Cyanoamino acid metabolism"
XP_044267293.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_044269873.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044268796.1	7	MetaCyc: PWY-6922;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-31	"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Arginine and proline metabolism";"Urea cycle";"Arginine biosynthesis";"Urea cycle";"Canavanine degradation"
XP_044269861.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_044258553.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780	"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome"
XP_044264799.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044269454.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044255083.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044263306.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_044263489.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044263421.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044256837.1	11	Reactome: R-HSA-171007;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097	"p38MAPK events";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_044255059.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044263063.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044263853.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_044255525.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044271192.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044257304.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044265884.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_044264660.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044258641.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044265920.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_044255945.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044263599.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044272487.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044256815.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_044261111.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044265292.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044267307.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_044254954.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044254780.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044255060.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044271140.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044269729.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044263856.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_044256771.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044256138.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_044268163.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044265535.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_044267626.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044266522.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_044267627.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044267921.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044270452.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_044265912.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044255227.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_044272216.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044256054.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044258136.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_044269827.1	2	Reactome: R-HSA-210746;Reactome: R-HSA-210745	"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells"
XP_044257426.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044264518.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_044255229.1	5	MetaCyc: PWY-7176;MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2	"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism"
XP_044261594.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_044262315.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044256848.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044270785.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_044264038.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_044257996.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_044270978.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes"
XP_044252673.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044267529.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044264697.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_044269915.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017	"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_044257894.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044257289.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485	"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis"
XP_044267091.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044267518.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044265543.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044258347.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9614399	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors"
XP_044266472.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044262279.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_044272269.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_044261107.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044265826.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_044271982.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044269366.1	17	Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-174414	"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere"
XP_044264190.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_044262579.1	6	KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241	"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Peroxisomal protein import"
XP_044266748.1	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
XP_044264466.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-933541	"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation"
XP_044254627.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044271259.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_044266821.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044258186.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736	"Long-term potentiation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors"
XP_044271367.1	8	Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5738;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-5740	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis"
XP_044263510.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044270931.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_044271055.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_044258662.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_044253685.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_044271944.1	44	Reactome: R-HSA-6802946;Reactome: R-HSA-5663213;Reactome: R-HSA-5654733;Reactome: R-HSA-2559580;Reactome: R-HSA-6802948;Reactome: R-HSA-5674499;Reactome: R-HSA-2559582;KEGG: 04150+2.7.11.24;Reactome: R-HSA-8940973;Reactome: R-HSA-450341;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-9627069;Reactome: R-HSA-1295596;Reactome: R-HSA-881907;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-6802952;Reactome: R-HSA-202670;Reactome: R-HSA-170968;Reactome: R-HSA-162658;Reactome: R-HSA-9634638;Reactome: R-HSA-5654726;Reactome: R-HSA-8943724;Reactome: R-HSA-3371453;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;Reactome: R-HSA-445144;Reactome: R-HSA-8939211;Reactome: R-HSA-74749;Reactome: R-HSA-5674135;Reactome: R-HSA-2029482;Reactome: R-HSA-444257;Reactome: R-HSA-9635465;Reactome: R-HSA-5668599;Reactome: R-HSA-6811558;Reactome: R-HSA-982772;Reactome: R-HSA-2871796;Reactome: R-HSA-375165;Reactome: R-HSA-198753;Reactome: R-HSA-456926;Reactome: R-HSA-879415;Reactome: R-HSA-5654727	"Signaling by moderate kinase activity BRAF mutants";"RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR4 signaling";"Oxidative Stress Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Senescence-Associated Secretory Phenotype (SASP)";"mTOR signaling pathway";"RUNX2 regulates osteoblast differentiation";"Activation of the AP-1 family of transcription factors";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Regulation of the apoptosome activity";"Spry regulation of FGF signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"Signaling by BRAF and RAF fusions";"ERKs are inactivated";"Frs2-mediated activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR1 signaling";"Regulation of PTEN gene transcription";"Regulation of HSF1-mediated heat shock response";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"Signal transduction by L1";"ESR-mediated signaling";"Signal attenuation";"MAP2K and MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"RSK activation";"Suppression of apoptosis";"RHO GTPases Activate NADPH Oxidases";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Growth hormone receptor signaling";"FCERI mediated MAPK activation";"NCAM signaling for neurite out-growth";"ERK/MAPK targets";"Thrombin signalling through proteinase activated receptors (PARs)";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR2 signaling"
XP_044255372.1	26	Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973	"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_044265404.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044263283.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_044256443.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism"
XP_044261344.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044262403.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044258344.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_044259747.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044259846.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_044260137.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044255591.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044259487.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_044266530.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044267231.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044271756.1	6	MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
XP_044265196.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044255936.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044269065.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_044260130.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_044272470.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044266927.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044258137.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_044266718.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_044272389.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044254591.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044258907.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044255393.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257174.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044272189.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044268701.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_044255805.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044266902.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_044252671.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044268480.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_044261700.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044256461.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044254748.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183	"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_044256555.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044269767.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044270793.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044268065.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044272454.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044266707.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044252863.1	17	MetaCyc: PWY-6611;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-7179;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine metabolism";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism"
XP_044272283.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044264333.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_044260497.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948	"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants"
XP_044270857.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_044259658.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044255934.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044263684.1	5	KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism"
XP_044269710.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044256552.1	8	Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
XP_044254706.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044256969.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044252650.1	3	Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_044259412.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044270576.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_044258316.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_044253406.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044259175.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044262265.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044258976.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_044255496.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044264925.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044256109.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_044252460.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044257374.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044269505.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044271327.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_044256400.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-189085	"ABC transporters in lipid homeostasis";"Digestion of dietary carbohydrate"
XP_044263603.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044260871.1	15	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence"
XP_044256396.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_044272696.1	8	Reactome: R-HSA-4641263;Reactome: R-HSA-373080;Reactome: R-HSA-8856828;Reactome: R-HSA-5340588;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-4608870;Reactome: R-HSA-4086398	"Regulation of FZD by ubiquitination";"Class B/2 (Secretin family receptors)";"Clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"Ca2+ pathway"
XP_044271082.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044271133.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044254756.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044267240.1	25	Reactome: R-HSA-8877330;Reactome: R-HSA-8941858;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8934593;Reactome: R-HSA-8951936;Reactome: R-HSA-8939236;Reactome: R-HSA-8939246;Reactome: R-HSA-8939247;Reactome: R-HSA-8939242;Reactome: R-HSA-8941326;Reactome: R-HSA-8939256;Reactome: R-HSA-8936459;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245;Reactome: R-HSA-8939243;Reactome: R-HSA-8941332;Reactome: R-HSA-8941284;Reactome: R-HSA-9616222;Reactome: R-HSA-8931987;Reactome: R-HSA-8878166;Reactome: R-HSA-8949275;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519	"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX3 expression and activity";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates chondrocyte maturation";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates estrogen receptor mediated transcription";"Transcriptional regulation by RUNX2";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression"
XP_044253653.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_044264801.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044271688.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_044268999.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_044254653.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044255997.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044256904.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044262005.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920	"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability"
XP_044266642.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044267192.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044255814.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044261076.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_044267234.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_044252912.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044254877.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044271042.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_044257976.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_044267903.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044269654.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044262347.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044270180.1	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_044268311.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044260359.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044258423.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044268650.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_044260572.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_044269453.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044262311.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044255637.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044256861.1	4	MetaCyc: PWY-8026;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72	"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis"
XP_044270162.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044255373.1	26	Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862	"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_044262298.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044259369.1	6	KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)"
XP_044263912.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044252924.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044271397.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044253746.1	12	MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism"
XP_044254511.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044259436.1	4	Reactome: R-HSA-8849471;Reactome: R-HSA-2029482;Reactome: R-HSA-164944;Reactome: R-HSA-4420097	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of actin dynamics for phagocytic cup formation";"Nef and signal transduction";"VEGFA-VEGFR2 Pathway"
XP_044262838.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044254493.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044267818.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044264674.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_044254602.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_044267624.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044258348.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044265833.1	8	MetaCyc: PWY-4984;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-7400;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1	"Urea cycle";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis"
XP_044269573.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_044266706.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044253911.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044260538.1	3	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984	"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_044257580.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_044256772.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044255260.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044254337.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044254824.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044266444.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-428540	"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Activation of RAC1"
XP_044266447.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753	"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions"
XP_044261362.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_044272547.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044272833.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_044268586.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_044267795.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_044272344.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_044272627.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044268296.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507	"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation"
XP_044260630.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857	"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Keratan sulfate degradation"
XP_044272831.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_044263620.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_044257184.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044256116.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_044270184.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044270762.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_044267773.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_044270599.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_044254228.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044272794.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044260407.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044262212.1	8	KEGG: 00220+6.3.4.5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-4984;MetaCyc: PWY-5	"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Canavanine biosynthesis"
XP_044268000.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044270312.1	6	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044272047.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044272471.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044261979.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044265524.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044260146.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044270204.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044253133.1	7	KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_044272261.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis"
XP_044259108.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044267932.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_044263779.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044256680.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_044258210.1	6	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_044261772.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_044261035.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044263956.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_044263954.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044258378.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044267521.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044270301.1	12	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Thermogenesis";"G alpha (12/13) signalling events";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human papillomavirus infection"
XP_044263872.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044252959.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044259000.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_044259339.1	5	Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621	"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_044260931.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044257340.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254873.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044252751.1	8	MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6580	"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_044260688.1	24	Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-418217	"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta"
XP_044261224.1	14	MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044265705.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044269835.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_044258604.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259012.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_044271091.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_044257846.1	8	KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_044265699.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_044269351.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
XP_044264082.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044263715.1	12	MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5872	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_044266652.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044256769.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044268735.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_044262274.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044258264.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044269122.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044260862.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599	"Carnitine metabolism";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_044270767.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_044253107.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044267282.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044260938.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_044262239.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044254194.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044263437.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_044255380.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_044267088.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_044259611.1	4	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_044254693.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_044263790.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044272360.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs"
XP_044262361.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044254380.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_044253941.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044272163.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044262946.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044256515.1	7	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis"
XP_044258570.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440	"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_044259234.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_044256757.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_044265651.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044262517.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257657.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044266187.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044261597.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_044254249.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_044268837.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044261129.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044262764.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044266544.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044272666.1	9	Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18	"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_044261255.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044264084.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_044257708.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_044270163.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044264096.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044260567.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044257784.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044261695.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation"
XP_044266698.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044269239.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_044268657.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_044264057.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044263214.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_044254845.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044268436.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044272005.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_044263470.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"DNA Damage Recognition in GG-NER";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_044255813.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044272476.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044255268.1	4	MetaCyc: PWY-5691;MetaCyc: PWY-7849;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394	"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Purine metabolism";"Urate conversion to allantoin II"
XP_044264121.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044270906.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044266689.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044254104.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_044268938.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044268491.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044259646.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044270196.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_044252701.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_044253385.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044268531.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044267261.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_044255367.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_044264815.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044264024.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044266380.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044265407.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_044257655.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044263669.1	6	Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781	"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"PPARA activates gene expression"
XP_044264517.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_044253134.1	7	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_044255627.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044256095.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044270445.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044256828.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_044253225.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044263582.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_044254996.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044254747.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781	"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression"
XP_044260292.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044257824.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-5610785;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-8853659;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-983231;Reactome: R-HSA-163358;Reactome: R-HSA-8963896;Reactome: R-HSA-111931;Reactome: R-HSA-5621575;Reactome: R-HSA-5610787;Reactome: R-HSA-9634600;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-442720;Reactome: R-HSA-392517;Reactome: R-HSA-5610780;Reactome: R-HSA-432040;Reactome: R-HSA-9010642;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163560	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"GLI3 is processed to GLI3R by the proteasome";"DARPP-32 events";"PKA activation in glucagon signalling";"RET signaling";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"Factors involved in megakaryocyte development and platelet production";"PKA-mediated phosphorylation of key metabolic factors";"HDL assembly";"PKA-mediated phosphorylation of CREB";"CD209 (DC-SIGN) signaling";"Hedgehog 'off' state";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Rap1 signalling";"Degradation of GLI1 by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"ROBO receptors bind AKAP5";"mTOR signaling pathway";"Triglyceride catabolism"
XP_044268028.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis"
XP_044267517.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044260333.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_044268166.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044261660.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044266036.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044270749.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044269910.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_044252515.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044265425.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_044267621.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044268194.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044258431.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_044260919.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044257445.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044268110.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_044268576.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_044272349.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044268831.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_044255752.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_044259503.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_044258962.1	8	Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207	"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_044261829.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_044260456.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044253790.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044260655.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044259233.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_044257712.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-167590	"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation"
XP_044265046.1	12	MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation"
XP_044265656.1	12	Reactome: R-HSA-8853383;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23	"Lysosomal oligosaccharide catabolism";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Other glycan degradation";"Other glycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism"
XP_044258417.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044266382.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044256237.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044266781.1	21	MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7221;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7205;MetaCyc: PWY-7219	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"CMP phosphorylation";"Adenosine ribonucleotides de novo biosynthesis"
XP_044264342.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044254769.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_044258460.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044259041.1	9	KEGG: 00510+2.4.1.141;MetaCyc: PWY-6385;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-6470;Reactome: R-HSA-5633231	"N-Glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_044256098.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044261400.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165	"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_044255931.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044255360.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044253565.1	7	Reactome: R-HSA-418594;Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-114608	"G alpha (i) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation"
XP_044270993.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044259861.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044267866.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044258380.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044264335.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_044262567.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044264424.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044255520.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_044267555.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044263355.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044269909.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_044271251.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044252821.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_044264321.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044262052.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044269283.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_044259727.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_044252412.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_044267907.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044267465.1	4	Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
XP_044253723.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044268713.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044269340.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044259788.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044253780.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72165	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway"
XP_044261144.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552	"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin"
XP_044270371.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167242	"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_044271424.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044269524.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044260743.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044253660.1	10	MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-7112	"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification"
XP_044265649.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044260609.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044252553.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_044269955.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044257375.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044261268.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_044265985.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044258379.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044257688.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_044253390.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044267446.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044252778.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044255804.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044256147.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253	"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock"
XP_044268970.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_044269608.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044270509.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_044260996.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_044255277.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_044252320.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044267087.1	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;MetaCyc: PWY-7511	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Protein ubiquitination"
XP_044253762.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044271893.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_044256959.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044261439.1	12	Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_044262166.1	6	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism"
XP_044261520.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_044265055.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-7863;MetaCyc: PWY-5523;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism"
XP_044270023.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_044265724.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6369;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism"
XP_044252623.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_044263915.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044260336.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044254223.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044255046.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_044271810.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_044269374.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_044255237.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes"
XP_044257332.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_044254106.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044272297.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_044257534.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044269614.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-432040	"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Hedgehog 'off' state";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_044267725.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044254413.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_044257245.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_044257663.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_044252806.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044259951.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044268790.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044270560.1	18	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_044261779.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044271351.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_044267702.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-205043	"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus"
XP_044260131.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_044252923.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044266104.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044265770.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044257953.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044271117.1	8	Reactome: R-HSA-6783310;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Fanconi Anemia Pathway";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044254526.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044267913.1	4	KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_044267890.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044272195.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
XP_044267048.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044269683.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044252619.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044265207.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044252559.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044268259.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_044252930.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044269468.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044255889.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044259005.1	13	MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916	"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation"
XP_044267753.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044262134.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_044261396.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044257292.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_044253404.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044266828.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044262273.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044265254.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_044271780.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044260404.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044255358.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044270201.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044258543.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_044261936.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044272388.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044255580.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044255980.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044257540.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_044258440.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044268068.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044259527.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"IRF3-mediated induction of type I IFN";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Human cytomegalovirus infection";"Cytosolic sensors of pathogen-associated DNA";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044253325.1	5	KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification"
XP_044269898.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044260360.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044255620.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_044272044.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044256787.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_044266890.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044254185.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_044270995.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044268514.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_044263949.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044264538.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_044255361.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044267272.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044258694.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044258005.1	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_044257664.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_044254885.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_044261704.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_044260453.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044262677.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254220.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044258827.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_044260592.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257860.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044270244.1	4	KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_044272148.1	13	Reactome: R-HSA-202433;MetaCyc: PWY-8052;Reactome: R-HSA-2871809;Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-2029485	"Generation of second messenger molecules";"2-arachidonoylglycerol biosynthesis";"FCERI mediated Ca+2 mobilization";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis"
XP_044272532.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA"
XP_044271519.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044272722.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_044271389.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044256488.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044266986.1	4	KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_044253839.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044267511.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044262208.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044255428.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044263933.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044260470.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_044256559.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044264758.1	13	KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism"
XP_044262262.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044271906.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_044265009.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_044256386.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism"
XP_044270307.1	12	Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1	"G alpha (12/13) signalling events";"Rho GTPase cycle";"Thermogenesis";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human cytomegalovirus infection"
XP_044259653.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"HCMV Early Events";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism"
XP_044268940.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044260297.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_044268193.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044270363.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_044258188.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_044267839.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044260226.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044271907.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587	"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
XP_044253792.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044254090.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514	"Chitin degradation I (archaea)";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_044271895.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_044257750.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044260868.1	15	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks"
XP_044258122.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044268374.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044255329.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044261008.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044270844.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_044261706.1	32	Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events"
XP_044255454.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_044265545.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044253912.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044265743.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044261840.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_044264809.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_044266103.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_044253574.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68962	"DNA replication initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex"
XP_044260288.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044258821.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044267072.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044263601.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_044268577.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_044269299.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_044267752.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044267784.1	16	Reactome: R-HSA-9664565;Reactome: R-HSA-1251985;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1963640;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631	"Signaling by ERBB2 KD Mutants";"Nuclear signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility"
XP_044254480.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044262597.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044260752.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044263139.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044264199.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_044263135.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-111465	"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins"
XP_044252459.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_044271897.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_044254560.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044263739.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_044267553.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044253295.1	5	Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation"
XP_044262164.1	6	KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_044264781.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_044258612.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044272099.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044256097.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044271738.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044266134.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044262756.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_044257809.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044263178.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_044255879.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044272419.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_044270580.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_044255313.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044260239.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044257783.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044258868.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044253791.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044266413.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044267650.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_044252461.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_044259415.1	8	MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481	"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate"
XP_044256369.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_044261115.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044255583.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044261611.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_044260661.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044252927.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044264309.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_044268466.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination"
XP_044257714.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044266777.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_044255973.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044269087.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_044255993.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Androgen biosynthesis"
XP_044265894.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044257267.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257397.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044268647.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_044263159.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_044262904.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_044255584.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044266647.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044256915.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044267898.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044272357.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044264893.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044258207.1	6	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_044260257.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044264352.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_044258665.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949	"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin"
XP_044253845.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044266190.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044257909.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_044263700.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_044262310.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044262242.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044264171.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044252434.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Neddylation";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D"
XP_044270020.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6796648	"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes"
XP_044266451.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044255002.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_044262444.1	7	Reactome: R-HSA-983168;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_044253440.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_044269564.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044271747.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044257594.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044263981.1	4	Reactome: R-HSA-70921;KEGG: 00340+4.3.1.3;MetaCyc: PWY-5030;MetaCyc: PWY-5028	"Histidine catabolism";"Histidine metabolism";"L-histidine degradation III";"L-histidine degradation II"
XP_044254350.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044269324.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination"
XP_044269318.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_044261682.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-196025	"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions"
XP_044272653.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_044254713.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_044252570.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044269387.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044268803.1	52	Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-5250924;Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-75955	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"B-WICH complex positively regulates rRNA expression";"MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation"
XP_044259885.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044260301.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_044264785.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044265663.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254173.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_044266303.1	19	Reactome: R-HSA-114604;Reactome: R-HSA-418885;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-983231;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-182971;Reactome: R-HSA-3928662;Reactome: R-HSA-194840	"GPVI-mediated activation cascade";"DCC mediated attractive signaling";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Factors involved in megakaryocyte development and platelet production";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"EGFR downregulation";"EPHB-mediated forward signaling";"Rho GTPase cycle"
XP_044265688.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_044252898.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-75815	"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D"
XP_044272039.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044263321.1	56	Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902	"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Neddylation";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity"
XP_044264192.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044258467.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044268243.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044269549.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259225.1	17	MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_044265206.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044271430.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044266372.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044253124.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_044257294.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_044260204.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044268766.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_044266406.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_044263291.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_044268367.1	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_044259518.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_044255717.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044253596.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044254323.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_044257087.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044263638.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044260040.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044272587.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_044262621.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_044269182.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_044259333.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_044268882.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_044265376.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044271365.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_044253950.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_044258321.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_044267882.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257444.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044260632.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_044263267.1	6	Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613	"Mitochondrial protein import";"ATP biosynthesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Cristae formation"
XP_044272012.1	14	MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-5484	"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)"
XP_044272445.1	7	MetaCyc: PWY-5695;Reactome: R-HSA-6798695;MetaCyc: PWY-6596;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205	"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
XP_044263655.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044271626.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044267428.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044261239.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044256313.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044266364.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_044258978.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_044255806.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044268910.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044264343.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044267263.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_044253299.1	9	Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901	"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_044262138.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044261331.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_044254632.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_044267184.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044263644.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044265693.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_044255718.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254985.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_044263209.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_044253969.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044265215.1	5	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism"
XP_044253364.1	4	MetaCyc: PWY-7919;Reactome: R-HSA-901032;KEGG: 00513+3.2.1.113;KEGG: 00510+3.2.1.113	"Protein N-glycosylation processing phase (plants and animals)";"ER Quality Control Compartment (ERQC)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_044267202.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_044269565.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_044252735.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_044266415.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044262640.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044263652.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044259150.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_044261698.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044258324.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_044260642.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044257409.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828	"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis"
XP_044270864.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_044259822.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_044272188.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044269578.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044263380.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_044269400.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044263431.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_044267557.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044271739.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044261589.1	12	KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Methane metabolism";"Glycolysis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_044254753.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events"
XP_044266929.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_044261005.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044255901.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes"
XP_044257528.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044269390.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044266035.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044256108.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044265064.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_044254267.1	9	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_044266557.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_044263413.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_044266988.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Macroautophagy";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044260927.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044266428.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044261826.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_044257002.1	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_044253661.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112	"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification"
XP_044265723.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044266188.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044268070.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling"
XP_044261600.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044258456.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_044261705.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_044264374.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044269876.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_044271754.1	6	MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17	"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism"
XP_044271835.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_044261825.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_044254501.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_044267675.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044266716.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_044259631.1	6	MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_044261872.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_044257595.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044266734.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Neutrophil degranulation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D"
XP_044253696.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168	"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256478.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044272615.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044253765.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044253149.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044270901.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044262264.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044262436.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_044266208.1	13	MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5537	"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V"
XP_044271583.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_044267444.1	6	MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_044256583.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044258001.1	9	MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7385;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94	"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_044268783.1	13	MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism"
XP_044269315.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044255897.1	8	KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-71336;Reactome: R-HSA-5659996	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Rubisco shunt";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P"
XP_044261896.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_044270308.1	12	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Human papillomavirus infection";"Thermogenesis";"G alpha (12/13) signalling events";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044266897.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044260223.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044271036.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044252877.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_044267873.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044264187.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044255900.1	14	Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-399997;Reactome: R-HSA-4086398;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-434316;Reactome: R-HSA-500657;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-418217	"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Acetylcholine regulates insulin secretion";"Ca2+ pathway";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Presynaptic function of Kainate receptors";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta"
XP_044266820.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044267498.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044272811.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044259063.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044255225.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_044263558.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044271262.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044260479.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_044268246.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044268574.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_044252676.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_044257343.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259622.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_044253515.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5651801	"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair"
XP_044259815.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044265604.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044258782.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044265520.1	22	KEGG: 00500+5.3.1.9;Reactome: R-HSA-6798695;MetaCyc: PWY-6981;MetaCyc: PWY-7347;MetaCyc: PWY-5384;MetaCyc: PWY-7238;Reactome: R-HSA-70263;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5054;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70171;MetaCyc: PWY-6992;MetaCyc: PWY-7385;MetaCyc: PWY-5659;MetaCyc: PWY-5514;MetaCyc: PWY-3801;MetaCyc: PWY-622;MetaCyc: PWY-621;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-8013	"Starch and sucrose metabolism";"Neutrophil degranulation";"Chitin biosynthesis";"Sucrose biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose biosynthesis II";"Gluconeogenesis";"Pentose phosphate pathway";"D-sorbitol biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"1,5-anhydrofructose degradation";"1,3-propanediol biosynthesis (engineered)";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Starch biosynthesis";"Sucrose degradation III (sucrose invertase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_044253888.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_044269709.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044262566.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_044261108.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044259994.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
XP_044253744.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_044271407.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044254459.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483	"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs"
XP_044255522.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_044253418.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_044253437.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044253952.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_044259112.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044264676.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_044252939.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044253358.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044262225.1	6	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_044268061.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_044260490.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135	"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation"
XP_044257412.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_044268446.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044259336.1	23	Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-456926	"Ca2+ pathway";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G alpha (q) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_044271650.1	11	MetaCyc: PWY-6608;MetaCyc: PWY-6596;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6999;MetaCyc: PWY-6606;Reactome: R-HSA-8851680;MetaCyc: PWY-5695	"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Purine catabolism";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Guanosine nucleotides degradation II";"Butyrophilin (BTN) family interactions";"Inosine 5'-phosphate degradation"
XP_044254830.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_044262210.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044265302.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_044260200.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044258273.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044259519.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_044265519.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_044269385.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044256107.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_044272354.1	14	Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397	"Translesion synthesis by POLI";"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_044253348.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_044257576.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_044269248.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044253036.1	3	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_044264021.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_044260978.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044262276.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044256875.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_044256558.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044270306.1	12	Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885	"Rho GTPase cycle";"G alpha (12/13) signalling events";"Thermogenesis";"Human papillomavirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"DCC mediated attractive signaling"
XP_044260080.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044258933.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044263940.1	7	KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-7807;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-7805	"Purine metabolism";"Purine salvage";"Glyphosate degradation III";"Adenine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation"
XP_044257677.1	5	MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis"
XP_044262623.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_044258419.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_044265091.1	40	Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167246	"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript"
XP_044262326.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_044259231.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044265336.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044267962.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044259825.1	27	Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-159231;Reactome: R-HSA-77588;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-159227;Reactome: R-HSA-975956;Reactome: R-HSA-111367;Reactome: R-HSA-72187;Reactome: R-HSA-112382;Reactome: R-HSA-159230;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-975957;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-191859;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Transport of the SLBP independent Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA 3'-end processing";"Formation of RNA Pol II elongation complex";"Transport of the SLBP Dependant Mature mRNA";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"snRNP Assembly";"RNA Polymerase II Transcription Termination"
XP_044271787.1	2	Reactome: R-HSA-211999;Reactome: R-HSA-211981	"CYP2E1 reactions";"Xenobiotics"
XP_044253265.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044260519.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044257467.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_044261459.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_044258418.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_044266371.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044254084.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044255462.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044272285.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_044268573.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_044267383.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044271947.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044256243.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_044271981.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_044259544.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6798695	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation"
XP_044261140.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044257285.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-2871809	"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Ca2+ pathway";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization"
XP_044259314.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_044256014.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_044258116.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571	"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation"
XP_044260194.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_044255431.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044263691.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5632684	"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Hedgehog 'on' state"
XP_044260090.1	3	Reactome: R-HSA-427389;Reactome: R-HSA-8953750;Reactome: R-HSA-73772	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape"
XP_044255469.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044264167.1	17	KEGG: 04660+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167246;KEGG: 04658+3.1.3.16;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242	"T cell receptor signaling pathway";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Th1 and Th2 cell differentiation";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_044261202.1	40	KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6435;MetaCyc: PWY-7779;MetaCyc: PWY-7654;MetaCyc: PWY-7094;MetaCyc: PWY-7007;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-6944;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7656;MetaCyc: PWY-6883;KEGG: 00592+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-5136;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7778;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00903+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7401	"Caprolactam degradation";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Tryptophan metabolism";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"4-hydroxybenzoate biosynthesis III (plants)";"Methyl tert-butyl ether degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid salvage";"Methyl ketone biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Benzoyl-coa degradation I (aerobic)";"Androstenedione degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol II (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Toluene degradation";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Fermentation to 2-methylbutanoate";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"2-methylpropene degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Glutaryl-coa degradation";"Limonene and pinene degradation";"Phenylalanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)"
XP_044264053.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_044256827.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044271313.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_044272042.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044269310.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044271364.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_044254988.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044272613.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044253972.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044269002.1	13	KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-1660662	"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism"
XP_044262309.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_044262905.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_044271785.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044257778.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_044253551.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_044264361.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_044272528.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044257859.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044254957.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044270999.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044259168.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_044262766.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044254720.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044259730.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044254028.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_044254888.1	11	MetaCyc: PWY-5381;MetaCyc: PWY-7185;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5	"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Purine metabolism"
XP_044262437.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_044255097.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_044271328.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_044255493.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044270886.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_044271834.1	18	KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00380+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-389661;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;KEGG: 00260+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-6783984	"Lysine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Glycolysis / Gluconeogenesis";"Lysine catabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Glycine, serine and threonine metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine degradation"
XP_044259868.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_044257313.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_044266311.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_044253544.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_044263248.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044262492.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044272495.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044257463.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044258639.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044259950.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_044259670.1	6	MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_044252569.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044272628.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044265883.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_044260334.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044258168.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044258458.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044260510.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044256767.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044266210.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725	"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_044269391.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044257858.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044267246.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes"
XP_044262296.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044255433.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_044256241.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044272118.1	5	KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556	"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"ROS and RNS production in phagocytes"
XP_044267820.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044256908.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044260015.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-8955332	"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Gap junction assembly";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin"
XP_044260163.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_044271464.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044266926.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044257659.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044264118.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854	"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly"
XP_044272011.1	14	MetaCyc: PWY-6901;MetaCyc: PWY-2221;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-1622	"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)"
XP_044265366.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044260641.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_044264022.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044253215.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_044264988.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_044269285.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044263233.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_044265442.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_044254186.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_044266417.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_044267680.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I"
XP_044266688.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_044260833.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation"
XP_044266414.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044259553.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044269214.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-983168	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044266075.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_044254177.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_044258452.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044257287.1	13	Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-4086398	"Effects of PIP2 hydrolysis";"Ion homeostasis";"Regulation of insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway"
XP_044257141.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044255008.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044255286.1	8	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy"
XP_044272705.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044258638.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044266398.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044261433.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044254785.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044271276.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-7388;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-8047;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7858	"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Pederin biosynthesis";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II"
XP_044269579.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044272386.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044266663.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_044271710.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine"
XP_044252994.1	12	MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism"
XP_044257666.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044269828.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044259661.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_044260759.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_044257434.1	16	Reactome: R-HSA-1660499;Reactome: R-HSA-9009391;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695	"Synthesis of PIPs at the plasma membrane";"Extra-nuclear estrogen signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"Rho GTPase cycle";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"RET signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling"
XP_044272815.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_044261796.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism"
XP_044254721.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_044268537.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_044263270.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044263212.1	12	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417	"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_044269507.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044261794.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_044257349.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044264754.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52	"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation"
XP_044272296.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044265887.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_044254384.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_044256177.1	7	Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;MetaCyc: PWY-6368	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation"
XP_044268121.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1	"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism"
XP_044263708.1	7	KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661;Reactome: R-HSA-71064	"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism"
XP_044260722.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044258507.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_044252884.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044253357.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044268007.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_044270964.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044267174.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_044258174.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044267492.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_044272322.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044269684.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044259194.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044260977.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044264714.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_044257608.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes"
XP_044269338.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044270977.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_044254512.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044257132.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_044264228.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044265044.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044271053.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044270095.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044266839.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044254203.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044264603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044265881.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_044264523.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044262754.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria"
XP_044260551.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044256316.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044254567.1	4	KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_044260020.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044255379.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_044266119.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044257382.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044270164.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044264564.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044272614.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044259504.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_044258969.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_044264675.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044268640.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044261470.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_044253167.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269043.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044266193.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044254596.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_044259420.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_044258203.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692	"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity"
XP_044260207.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044260350.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_044257293.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_044269897.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation"
XP_044272273.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044271112.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_044270423.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation"
XP_044271514.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-918233;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"HATs acetylate histones";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase"
XP_044272088.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044265014.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044271433.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044265954.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044255974.1	30	Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-8951664;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-2644607;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862	"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"Neddylation";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_044261962.1	13	Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-166208;Reactome: R-HSA-3371571	"Macroautophagy";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"mTOR signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"mTORC1-mediated signalling";"HSF1-dependent transactivation"
XP_044255365.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044260312.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044267709.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044257133.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_044269060.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044272265.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044253305.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism"
XP_044258733.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_044259524.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_044256213.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_044257886.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_044271648.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_044272287.1	58	Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5689901;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695	"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Metalloprotease DUBs";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Neutrophil degranulation"
XP_044254518.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044265727.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044271616.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044258463.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_044262295.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044268591.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_044257164.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044268855.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167242	"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_044255500.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044265644.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-8955332	"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Kinesins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin"
XP_044255828.1	11	Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-611105	"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport"
XP_044259844.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044257163.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044257325.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044264556.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044257807.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044264170.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044258875.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044262377.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_044256166.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_044267891.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044254894.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044268789.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044270569.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_044260552.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_044258346.1	4	Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017	"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_044256754.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends"
XP_044271264.1	3	Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
XP_044253964.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044265327.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044268841.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_044260757.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044256796.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044261028.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044257630.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_044255033.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044265977.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044272589.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044272270.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_044257609.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes"
XP_044255909.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_044268776.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_044264404.1	13	KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism"
XP_044267352.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256822.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_044269033.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-164378	"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling"
XP_044269444.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044263816.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_044262857.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044266238.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044259378.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044259543.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_044271176.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_044269401.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_044261694.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044252925.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044264834.1	5	Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-901032	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)"
XP_044261993.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
XP_044254107.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_044265580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269554.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044255927.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044253726.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044260896.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_044269256.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_044265261.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257995.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425	"Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_044260335.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044268594.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044261471.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_044258739.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_044263388.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044263991.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_044263683.1	5	KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation"
XP_044262725.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044264796.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044271723.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_044255519.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044255015.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044263010.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_044264370.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044267292.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_044265299.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_044263814.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_044262125.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_044272085.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044266144.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044265660.1	12	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972	"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Macroautophagy";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_044272038.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044269183.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_044261929.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_044264471.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_044269098.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"Neutrophil degranulation";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_044260440.1	20	KEGG: 00640+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-5172;MetaCyc: PWY-6728;MetaCyc: PWY-5537;Reactome: R-HSA-75105	"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis"
XP_044265969.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044254178.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_044252338.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044261038.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044272758.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044269603.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044252960.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044264327.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-180585	"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G"
XP_044259625.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753	"Neutrophil degranulation";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions"
XP_044254940.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044256394.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044257847.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis"
XP_044265446.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_044253504.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700	"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_044268889.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044252744.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_044264524.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_044262858.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044272747.1	17	KEGG: 05170+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756	"Human immunodeficiency virus 1 infection";"Meiotic synapsis";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Thermogenesis";"Human papillomavirus infection";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation"
XP_044261541.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044255849.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044258812.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044255801.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044254089.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514	"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_044267998.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044266402.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044257779.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_044262352.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_044263637.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044268113.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_044265160.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044255691.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_044258166.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044253489.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044260509.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044269619.1	16	Reactome: R-HSA-166058;Reactome: R-HSA-5602498;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-9020702;Reactome: R-HSA-1257604;Reactome: R-HSA-975871;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-5603041;Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-975155;Reactome: R-HSA-1236974;Reactome: R-HSA-5602680	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"Interleukin-1 signaling";"PIP3 activates AKT signaling";"MyD88 cascade initiated on plasma membrane";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 dependent cascade initiated on endosome";"ER-Phagosome pathway";"MyD88 deficiency (TLR5)"
XP_044255907.1	5	Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_044253102.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044262040.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044258282.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044268011.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_044271618.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044260369.1	3	KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism"
XP_044253373.1	7	Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_044257284.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044268067.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044256007.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044255708.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044270723.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_044265901.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044267649.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_044269253.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_044266192.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044258627.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044257306.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044260266.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_044260091.1	3	Reactome: R-HSA-427389;Reactome: R-HSA-8953750;Reactome: R-HSA-73772	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape"
XP_044262548.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044264622.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_044257907.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_044260618.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044254041.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_044256513.1	7	KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7176	"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Pyrimidine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis"
XP_044261529.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044266900.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044267073.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044270293.1	24	Reactome: R-HSA-444257;Reactome: R-HSA-114604;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-202424;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-9634635;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-165158	"RSK activation";"GPVI-mediated activation cascade";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Integrin signaling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Downstream TCR signaling";"Thermogenesis";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-stimulated signaling through PRKCZ";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"Activation of AKT2"
XP_044265056.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_044252469.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_044260465.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_044264734.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044259191.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044272748.1	17	Reactome: R-HSA-6783310;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Fanconi Anemia Pathway";"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway";"Meiotic synapsis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_044267226.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_044268955.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519	"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression"
XP_044269646.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_044254019.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044265749.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044259848.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_044260133.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_044263205.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044271781.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044267313.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044264757.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation"
XP_044257661.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044272826.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-8001	"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_044254587.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044260224.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044266395.1	22	MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7035;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7619;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7592;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044253580.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_044269147.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044270046.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_044258167.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_044255959.1	4	MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27	"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism"
XP_044266418.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044271533.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044263932.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044266391.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044270043.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044271446.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins"
XP_044257821.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044269676.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_044267351.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256592.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_044257344.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044262043.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044264878.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway"
XP_044257838.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_044267960.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949	"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin"
XP_044256407.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_044268925.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044267273.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_044254813.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044253803.1	13	KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Thermogenesis"
XP_044253582.1	8	MetaCyc: PWY-7717;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-5651;MetaCyc: PWY-7765;MetaCyc: PWY-7734;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Quinoxaline-2-carboxylate biosynthesis";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_044271048.1	29	Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5696400	"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Dual Incision in GG-NER"
XP_044255589.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044262826.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044268736.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_044258555.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044255753.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_044272538.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_044256395.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044252322.1	11	Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-450341;Reactome: R-HSA-5617472;Reactome: R-HSA-8862803;Reactome: R-HSA-1912408;Reactome: R-HSA-2559582;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of the AP-1 family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Pre-NOTCH Transcription and Translation";"Senescence-Associated Secretory Phenotype (SASP)";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_044272522.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044263281.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_044271755.1	6	KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221	"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_044254861.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044256378.1	10	MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)"
XP_044258171.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044269000.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_044262530.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044272325.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044257379.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044260735.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044262299.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044259714.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044262394.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-1989781	"Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"PPARA activates gene expression"
XP_044258286.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044267872.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044260983.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044260903.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044264216.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_044272172.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044259647.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044269638.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression"
XP_044268355.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_044253775.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259110.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044267396.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044264654.1	3	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695	"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation"
XP_044261272.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_044254351.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_044252590.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044263535.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044263624.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044253855.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044261828.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_044270972.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044267319.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade"
XP_044262345.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_044254875.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044257929.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044254204.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044270850.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_044263677.1	10	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"PERK regulates gene expression";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044255207.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044253853.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044272380.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044267462.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044268832.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044271431.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044264338.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044269145.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4	"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine metabolism"
XP_044272517.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044271725.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_044268806.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68962	"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Activation of the pre-replicative complex"
XP_044264772.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044263188.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_044265339.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044254841.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_044261104.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044257840.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044269681.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044261041.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044268391.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-200425	"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Carnitine metabolism"
XP_044268761.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_044255453.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044265662.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044255430.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044256370.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_044257878.1	33	Reactome: R-HSA-71384;MetaCyc: PWY-6871;MetaCyc: PWY-7798;MetaCyc: PWY-7396;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5480;MetaCyc: PWY-1801;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-5057;MetaCyc: PWY-7111;KEGG: 00071+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-6587;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-5751;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-5486;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-7013;MetaCyc: PWY-6342;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00010+1.1.1.1	"Ethanol oxidation";"3-methylbutanol biosynthesis (engineered)";"Protein S-nitrosylation and denitrosylation";"Butanol and isobutanol biosynthesis (engineered)";"Methane metabolism";"Pyruvate fermentation to ethanol I";"Formaldehyde oxidation II (glutathione-dependent)";"Metabolism of xenobiotics by cytochrome P450";"L-isoleucine degradation II";"Glycine, serine and threonine metabolism";"Acetaldehyde biosynthesis I";"L-valine degradation II";"Pyruvate fermentation to isobutanol (engineered)";"Fatty acid degradation";"L-tryptophan degradation V (side chain pathway)";"Tyrosine metabolism";"L-leucine degradation III";"Drug metabolism - cytochrome P450";"Salidroside biosynthesis";"Pyruvate fermentation to ethanol III";"Retinol metabolism";"L-methionine degradation III";"Phenylethanol biosynthesis";"Chloroalkane and chloroalkene degradation";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol II";"Naphthalene degradation";"Serotonin degradation";"(S)-propane-1,2-diol degradation";"Noradrenaline and adrenaline degradation";"alpha-Linolenic acid metabolism";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis"
XP_044272008.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_044269591.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_044258564.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044253266.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044264658.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_044262304.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044266019.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_044257460.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_044257643.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_044262871.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044264141.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_044252815.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_044261849.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044258315.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_044266090.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044271291.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_044264347.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044252436.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_044272180.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044266753.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_044256793.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044253898.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044258081.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736	"Long-term potentiation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors"
XP_044264864.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044270970.1	11	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_044264677.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_044270492.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756	"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_044260812.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044258247.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044267076.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044263740.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044265123.1	37	Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-9639288;Reactome: R-HSA-2467813;Reactome: R-HSA-204005;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-983170;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214	"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amino acids regulate mTORC1";"Separation of Sister Chromatids";"COPII-mediated vesicle transport";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins"
XP_044257644.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_044264181.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_044267708.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044262774.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044263148.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_044254619.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_044266549.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_044254176.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_044254229.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044254171.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_044261795.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044262599.1	5	KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;Reactome: R-HSA-70895	"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism"
XP_044264240.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044261641.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_044263688.1	7	KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_044254537.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044261401.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044265939.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044255458.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044262804.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214	"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins"
XP_044268482.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_044252807.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044262551.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044258361.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_044269587.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044265592.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_044258331.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_044269701.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044262793.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_044261174.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-8939243;Reactome: R-HSA-2559580	"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence"
XP_044261640.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_044259387.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_044258327.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044257151.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044267770.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044260309.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044253126.1	12	MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4	"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Glycerophospholipid metabolism"
XP_044265277.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_044268791.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"Kinesins"
XP_044268457.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_044264655.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044270073.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044260866.1	15	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends"
XP_044253683.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_044268362.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_044263680.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_044266829.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044271741.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044257918.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_044260513.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044268056.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044272366.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_044265414.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_044263629.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044258238.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044270898.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044269918.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044261656.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044260875.1	4	KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_044265827.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_044272659.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_044270413.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044253366.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_044266211.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_044253231.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044253949.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044259174.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044260727.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044267256.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409	"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_044255435.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
XP_044264116.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746	"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"HCMV Late Events";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein"
XP_044269187.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044255778.1	5	KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_044255378.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_044257979.1	5	MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_044256841.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044259004.1	15	Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407	"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_044254687.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins"
XP_044252429.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044258185.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_044254541.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044271743.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044255457.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044254758.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142	"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins"
XP_044257717.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_044270904.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044255960.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044254152.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044264726.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044262252.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044257915.1	14	MetaCyc: PWY-5103;MetaCyc: PWY-5104;KEGG: 00270+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5101;KEGG: 00966+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5057;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078	"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis IV";"Cysteine and methionine metabolism";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"Glucosinolate biosynthesis";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis V";"L-valine degradation II";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II"
XP_044253267.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044257928.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044263157.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382	"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex"
XP_044259062.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_044255310.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044254133.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044253422.1	5	Reactome: R-HSA-1483148;MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5	"Synthesis of PG";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism"
XP_044265328.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044267101.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044257372.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044262041.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044259629.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-75893	"Activated NOTCH1 Transmits Signal to the Nucleus";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling"
XP_044263967.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044260167.1	18	Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167287	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery"
XP_044261847.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_044267475.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_044269165.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044257527.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_044256749.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044272429.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044265142.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044263286.1	52	Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-72165;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-8851708	"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM"
XP_044262250.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-8049;MetaCyc: PWY-8047;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-7388;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41	"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism"
XP_044259612.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_044260879.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery"
XP_044266145.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_044263585.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044269373.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_044271962.1	16	Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-196025;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"Formation of annular gap junctions";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_044263625.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044259294.1	5	Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)"
XP_044270840.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_044259488.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_044261644.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058	"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling"
XP_044264992.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044266651.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044252655.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044261927.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_044261180.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_044255994.1	5	Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94	"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis"
XP_044262478.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_044270321.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044263461.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044269282.1	5	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_044258580.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation"
XP_044265784.1	4	Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260	"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_044256347.1	33	Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-165054	"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA"
XP_044263985.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044266178.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044255990.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176407	"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_044263679.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA"
XP_044269363.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_044265264.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_044262814.1	4	MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_044272120.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_044267289.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044253220.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_044267939.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044264475.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044260494.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-445355	"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_044259829.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_044256142.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_044270019.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044257690.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_044272159.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_044255682.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_044263978.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044266955.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044270313.1	6	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_044257149.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044258032.1	3	Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_044264915.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044271776.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044252576.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_044257590.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044271000.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044264227.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044270610.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516	"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation"
XP_044257642.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_044261444.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_044265750.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044259363.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044270896.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044262534.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044263417.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044271773.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_044255942.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044265775.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044261324.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044253656.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-198323	"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol"
XP_044262864.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-983168	"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044266147.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044254617.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_044253227.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_044270311.1	6	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044269166.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044263520.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044254423.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_044260503.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_044257402.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044271041.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044264079.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044266509.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69481	"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Neutrophil degranulation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"G2/M Checkpoints"
XP_044269711.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_044252594.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044258980.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_044270764.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_044256130.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044253731.1	12	KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;MetaCyc: PWY-6613;MetaCyc: PWY-6122;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9	"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate"
XP_044272363.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_044258637.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044263419.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044266532.1	5	MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I"
XP_044263167.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_044270909.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044256056.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_044264180.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_044257159.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_044252824.1	17	MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7197	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_044253431.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_044265643.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_044271707.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_044266165.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044263177.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044270566.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168271	"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_044271833.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044269160.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044269419.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_044258767.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044259682.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044255489.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock";"Downregulation of TGF-beta receptor signaling"
XP_044258275.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044253306.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_044265314.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-3232142	"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of ubiquitinylation proteins"
XP_044261330.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399	"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy"
XP_044253250.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_044255747.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044259996.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_044269099.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_044270418.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation"
XP_044271429.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044263583.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_044270536.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_044259991.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044268281.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_044264060.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_044263210.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_044270186.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044267927.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"ISG15 antiviral mechanism";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044266070.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044268395.1	17	Reactome: R-HSA-69231;Reactome: R-HSA-1912408;Reactome: R-HSA-113501;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-111448;Reactome: R-HSA-139915	"Cyclin D associated events in G1";"Pre-NOTCH Transcription and Translation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of NOXA and translocation to mitochondria";"Activation of PUMA and translocation to mitochondria"
XP_044269341.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044267522.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044271057.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_044263422.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044265335.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044253649.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044270034.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_044255259.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044261987.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87	"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis"
XP_044253471.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044271294.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044261781.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_044261445.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044260836.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-6282;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5989;MetaCyc: PWY-7746;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-8049;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-5973;MetaCyc: PWY-6519	"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I"
XP_044264804.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044253788.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044252958.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_044259272.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044268862.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044265538.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_044252632.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044257326.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044259749.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044261595.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_044264876.1	4	Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044267191.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044255731.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis"
XP_044267260.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_044262790.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044262717.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_044263686.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_044261659.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044252802.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044260658.1	29	Reactome: R-HSA-69541;Reactome: R-HSA-3371453;Reactome: R-HSA-349425;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-6803204;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-69473;Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803207	"Stabilization of p53";"Regulation of HSF1-mediated heat shock response";"Autodegradation of the E3 ubiquitin ligase COP1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"G2/M DNA damage checkpoint";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"Human papillomavirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_044256444.1	5	MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_044258271.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044263882.1	6	Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"ESR-mediated signaling"
XP_044267608.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044254523.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_044265641.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_044256406.1	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_044260164.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_044252825.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_044265184.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044263771.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_044252832.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_044258061.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044267819.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044266798.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044265717.1	14	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
XP_044258823.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044253680.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_044263264.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_044254729.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044261418.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044254331.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254871.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044255799.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044254620.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_044258789.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044257324.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044261176.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044265340.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044268010.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_044264589.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044258243.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_044258285.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044256666.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044255587.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044264001.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044267169.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044266425.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044260144.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_044265667.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044256840.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044258811.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044259823.1	10	MetaCyc: PWY-7394;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;MetaCyc: PWY-5691;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;MetaCyc: PWY-7849	"Urate conversion to allantoin II";"Neutrophil degranulation";"Purine metabolism";"Urate conversion to allantoin I";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III"
XP_044269404.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_044263774.1	17	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044263061.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044270318.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_044256897.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044270325.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_044259680.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044255917.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603	"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases"
XP_044260663.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902	"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"G2/M Checkpoints";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Neddylation";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity"
XP_044258552.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_044259270.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044255716.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044264954.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044271619.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044262278.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_044259546.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_044270097.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044272830.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_044254635.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044263277.1	6	MetaCyc: PWY-5789;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_044258732.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_044266409.1	11	MetaCyc: PWY-6969;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7124	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)"
XP_044259477.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_044255529.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_044270409.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044256346.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408	"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation"
XP_044270281.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044256877.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044255208.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044265734.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044264085.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_044255374.1	26	Reactome: R-HSA-2894862;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"Circadian Clock";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"HATs acetylate histones"
XP_044255940.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044263931.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044265687.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044263471.1	33	Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638	"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins"
XP_044269064.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_044258579.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_044260861.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044260346.1	40	Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044260331.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_044258606.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_044261540.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044254694.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044266033.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044265673.1	5	KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Heme biosynthesis"
XP_044265605.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044270827.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044258402.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_044259092.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_044256610.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_044265927.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044270911.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044263864.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044267339.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044262740.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport"
XP_044253360.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044255533.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044256233.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044266769.1	4	MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210	"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_044253563.1	7	Reactome: R-HSA-140837;Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-416476	"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events"
XP_044256933.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_044259116.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044268360.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_044268692.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_044257959.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_044259624.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_044270738.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044259338.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532	"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)"
XP_044265885.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_044264469.1	5	Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936440	"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling"
XP_044256949.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_044257098.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044265130.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044261599.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044264248.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044253817.1	6	Reactome: R-HSA-8862803;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-8950505;MetaCyc: PWY-6854	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)"
XP_044262167.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism"
XP_044271395.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044258276.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044268191.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044267853.1	11	Reactome: R-HSA-975634;KEGG: 00240+4.2.1.70;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;MetaCyc: PWY-6019;Reactome: R-HSA-3656253	"Retinoid metabolism and transport";"Pyrimidine metabolism";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Pseudouridine degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_044258041.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_044272536.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_044265122.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_044259381.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044256790.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044261266.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044263695.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_044265893.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044267493.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044269185.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044256460.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044268822.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching";"Termination of translesion DNA synthesis"
XP_044262672.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044264427.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-75815	"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D"
XP_044269672.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044262784.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_044260253.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156581	"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation"
XP_044261842.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044257433.1	16	Reactome: R-HSA-912631;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-389357;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-1257604	"Regulation of signaling by CBL";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"RET signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"PIP3 activates AKT signaling"
XP_044269492.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_044267288.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044266972.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_044268870.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044267794.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_044260294.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_044272332.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044262032.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_044252427.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044268161.1	11	Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597	"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events"
XP_044268274.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044271304.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_044256368.1	10	Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11	"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
XP_044259889.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746	"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein"
XP_044266200.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044266826.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044271040.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044268844.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044271325.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_044256803.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)"
XP_044259389.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_044252948.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044268273.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044267817.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044270271.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-381033;Reactome: R-HSA-8957275	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation"
XP_044266177.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044252804.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_044261422.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_044266175.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_044253823.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044256020.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603	"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases"
XP_044267790.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044264377.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044254492.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044264982.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044254111.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044260304.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_044271360.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_044265728.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044253577.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044270064.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593	"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity"
XP_044260576.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044253229.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044270611.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-114516	"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation"
XP_044254409.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_044270933.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_044259618.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044271838.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_044257339.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259998.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_044261097.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044271515.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-918233;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-201722	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"HATs acetylate histones";"Circadian Clock";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_044271704.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_044253976.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_044262433.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_044271813.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044260782.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_044260311.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044252404.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603	"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Neddylation";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases"
XP_044271908.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I"
XP_044271255.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044270865.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_044253121.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044264863.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044272117.1	5	MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
XP_044272126.1	14	MetaCyc: PWY-6901;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1622	"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)"
XP_044253249.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922	"Hedgehog 'off' state";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium"
XP_044265032.1	14	Reactome: R-HSA-4419969;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_044269754.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044258204.1	10	Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-447038	"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"NrCAM interactions"
XP_044271924.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_044254989.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044263386.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044267689.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_044270079.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044263720.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_044270934.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514	"Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_044253303.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_044261894.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_044262405.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044265876.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044262002.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_044264304.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_044266408.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044261382.1	10	MetaCyc: PWY-7996;MetaCyc: PWY-5891;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5844;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-5890	"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-10 biosynthesis"
XP_044268527.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044259849.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044255937.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044265068.1	10	MetaCyc: PWY-7328;MetaCyc: PWY-7344;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Galactose catabolism"
XP_044262100.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044259126.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_044263802.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044266638.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044260258.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044265802.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_044257167.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_044261065.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_044270195.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_044269450.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044257126.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044254346.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044261488.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_044264061.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_044255720.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044257892.1	7	Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-114608	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"Platelet degranulation"
XP_044257920.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_044260550.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_044265290.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_044257531.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044263228.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing"
XP_044252808.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044253768.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044267172.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044264922.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_044265921.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_044264088.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_044253966.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903	"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy"
XP_044255656.1	14	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_044260408.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_044267083.1	15	Reactome: R-HSA-9665245;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-1227986;Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665247	"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib"
XP_044269483.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044263414.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_044268040.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_044261651.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_044253933.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_044265258.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_044271534.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044253280.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044257129.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_044265816.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_044258115.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044269899.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation"
XP_044256204.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044269854.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044260225.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044256393.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044260783.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044259476.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_044272264.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_044258044.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_044263487.1	24	Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418217	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta"
XP_044255540.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044267181.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044271520.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044258455.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_044259742.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_044264376.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044266816.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4615885	"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins"
XP_044258461.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_044259277.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044260398.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_044265119.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-68962	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex"
XP_044256236.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044258447.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044264711.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_044259809.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_044258881.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044265132.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_044266728.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_044254746.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781	"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression"
XP_044253940.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044259654.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2"
XP_044262734.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254599.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8854214	"RAB geranylgeranylation";"TBC/RABGAPs"
XP_044257376.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044257695.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044259111.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044265491.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044252656.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044254571.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044262391.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_044266648.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_044264317.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_044263607.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044252883.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044265399.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_044266093.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_044261007.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044266646.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_044264238.1	6	MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606	"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Guanosine nucleotides degradation II"
XP_044271581.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_044260807.1	1	KEGG: 00030+1.1.1.47	"Pentose phosphate pathway"
XP_044271243.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044264525.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_044268666.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_044262406.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044253651.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_044256145.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-400253	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"Circadian Clock"
XP_044253978.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044259605.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044269839.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044261916.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_044262372.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044269157.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044267286.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044270766.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044264673.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044257378.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044257131.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_044266135.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_044267164.1	11	Reactome: R-HSA-912694;Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-389948	"Regulation of IFNA signaling";"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Interleukin-37 signaling";"PECAM1 interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"PD-1 signaling"
XP_044255412.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044256499.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269152.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044271234.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044265319.1	52	Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168	"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044270960.1	30	Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_044266640.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044264833.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-901032;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_044254867.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044264113.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_044258588.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_044262760.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_044253741.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_044266088.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044265882.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_044263646.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_044257128.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044267186.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044259298.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044252736.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_044265441.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_044266321.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044264659.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044265726.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044266117.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_044267284.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044261991.1	3	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_044264078.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-6978;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5857;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-5856;Reactome: R-HSA-2142789	"Ubiquinol-9 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
XP_044258511.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044266854.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044265746.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044259632.1	12	Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"TNF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_044257674.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_044262170.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism"
XP_044262582.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6	"Peroxisomal protein import";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism"
XP_044253820.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_044262092.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559	"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione degradation (DUG pathway"
XP_044257483.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044268428.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044261267.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044269499.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044271839.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"T cell receptor signaling pathway";"Thermogenesis"
XP_044256446.1	5	KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_044267190.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044254300.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044258205.1	6	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_044264439.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040	"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation"
XP_044268488.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044267125.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_044260441.1	20	MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-6728;Reactome: R-HSA-75105;MetaCyc: PWY-5537;Reactome: R-HSA-163765;KEGG: 00640+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;KEGG: 00660+6.2.1.5	"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Mitochondrial protein import";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"C5-Branched dibasic acid metabolism"
XP_044254689.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044257565.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044253759.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577	"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21"
XP_044266318.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_044264249.1	9	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication"
XP_044268768.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-179409	"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A"
XP_044271923.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_044263657.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044268792.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_044261178.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_044259034.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044263198.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044260486.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_044264696.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044257408.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_044257348.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044272166.1	6	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811434	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044263391.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_044266546.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044272585.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044257244.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_044254697.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_044260527.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044268153.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044269776.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_044266154.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044261167.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-8939243;Reactome: R-HSA-2559580	"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence"
XP_044264625.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044254407.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_044266230.1	13	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-216083	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Collagen degradation";"NCAM1 interactions";"Extracellular matrix organization";"Signaling by PDGF";"Laminin interactions";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions"
XP_044270910.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044257377.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044262787.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044253277.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_044253873.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561	"Ether lipid metabolism";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Glycerophospholipid metabolism";"Choline biosynthesis III"
XP_044260120.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044268245.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044261322.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_044265253.1	8	MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-2426168	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)"
XP_044272598.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044258562.1	7	KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms"
XP_044262301.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044256638.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044260648.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044269818.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044253700.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044261693.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_044265952.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044255593.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044259610.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_044264062.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_044265729.1	10	Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6361	"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_044254618.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044261332.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044256960.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044272275.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044272597.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044254436.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_044263147.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_044271642.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_044256045.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_044270450.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_044256458.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044256481.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_044257333.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_044272648.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_044272346.1	4	KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221	"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_044266300.1	5	Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation"
XP_044271686.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_044268533.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
XP_044265243.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044265134.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220	"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins"
XP_044254829.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_044264214.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_044269150.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044261518.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044259554.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044255608.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1	"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism"
XP_044268249.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_044271901.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_044258585.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis"
XP_044253610.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044270041.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_044268430.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_044253977.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044262297.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_044256836.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7291;Reactome: R-HSA-9033241	"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import"
XP_044264099.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044252803.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_044265190.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_044263955.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044266541.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660	"PKA activation";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway"
XP_044259679.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044266051.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_044266412.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044271385.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044256210.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_044271295.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044263746.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044264671.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044269712.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044266634.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_044259334.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044270565.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044269293.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044261130.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044261134.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044260415.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044268589.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_044257296.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_044253375.1	7	Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_044260256.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044253268.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044259202.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_044258413.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_044266383.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_044259306.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044263524.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044256595.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_044253808.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA"
XP_044254777.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044256024.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-1855204	"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol"
XP_044265611.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044264312.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_044253787.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044260172.1	31	MetaCyc: PWY-6113;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-6799;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-8049;MetaCyc: PWY-8047;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7746;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-7663	"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)"
XP_044257485.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044256252.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-2129379	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres"
XP_044266518.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_044268292.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_044264254.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044260912.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_044266693.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_044261571.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044267551.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044262305.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044256797.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044271505.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044253380.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_044254603.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_044254266.1	9	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_044265048.1	10	KEGG: 04150+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane"
XP_044271252.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044255336.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_044260750.1	10	MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901	"Entner-Doudoroff pathway I";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_044261620.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044270851.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044269548.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257369.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_044259882.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_044266259.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044268063.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_044262751.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_044258317.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_044258274.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044271902.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_044255058.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044258809.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_044258202.1	10	Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Long-term potentiation";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_044263586.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044264065.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044252563.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_044268197.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins"
XP_044264336.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_044271290.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044260834.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
XP_044272278.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044262445.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-983168	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044259648.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044265738.1	5	MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_044254846.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044264345.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044269328.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044253485.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044267912.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_044265949.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044253931.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_044261181.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_044264042.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044257125.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044258353.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_044261315.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_044264918.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044267161.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_044271972.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_044255622.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_044263945.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_044264350.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_044257529.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044264100.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044253813.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044258241.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_044265342.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_044254226.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044266598.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044259810.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_044258642.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
XP_044270897.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044262697.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_044263138.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044256498.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044262918.1	15	MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901	"Entner-Doudoroff pathway I";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation"
XP_044258411.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044254047.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044253951.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation"
XP_044256770.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044254660.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044270110.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044261666.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259392.1	8	MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate"
XP_044258199.1	10	Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_044266523.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_044264891.1	7	KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17	"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044253169.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044268839.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins"
XP_044270974.1	7	MetaCyc: PWY-7158;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208	"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine metabolism"
XP_044257857.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960	"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC"
XP_044263284.1	52	Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-5601884;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-1834949;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-72163	"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway"
XP_044264474.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044263875.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044261804.1	9	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_044269557.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044254568.1	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_044271406.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044254533.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_044255848.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044258697.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044268655.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044265821.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044266323.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044256206.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_044262758.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_044252574.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_044268478.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_044260935.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_044261099.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044269371.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_044261033.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044259644.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2"
XP_044257897.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142	"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins"
XP_044253550.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_044265767.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044257599.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_044265439.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044258170.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044253413.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044258598.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044267182.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_044257381.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044260170.1	31	MetaCyc: PWY-7663;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-6282;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWY-7746;MetaCyc: PWY-7388;MetaCyc: PWY-6799;MetaCyc: PWY-7723;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-8049;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-6519;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-5142	"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway"
XP_044265793.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_044271735.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044268563.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044266746.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_044268069.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044253442.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_044255041.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_044267502.1	12	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_044260753.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_044270790.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044271394.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044266436.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044253297.1	5	Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation"
XP_044261934.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-7587	"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
XP_044258532.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_044263815.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_044262269.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044254864.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044257387.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044257660.1	13	KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;MetaCyc: PWY-7118;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00010+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Ethanol oxidation";"Glycolysis / Gluconeogenesis"
XP_044270420.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events"
XP_044269149.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044271894.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_044255929.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044264337.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044259094.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_044266137.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_044267466.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044256399.1	52	Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-72165;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-5578749	"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Minor Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs"
XP_044264054.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044256874.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_044264565.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-174437	"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand"
XP_044272624.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044267089.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_044271599.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044265525.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
XP_044259888.1	31	MetaCyc: PWY-7663;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168	"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)"
XP_044257713.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044272595.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_044257835.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6122	"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_044257685.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044252745.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044271292.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044258582.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044259688.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_044259190.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044260575.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257628.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_044265331.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044255938.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044264723.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044264140.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044260072.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_044268858.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044262018.1	3	MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway"
XP_044265897.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_044258141.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_044263880.1	4	Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-176187	"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Activation of ATR in response to replication stress"
XP_044253595.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044255928.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256734.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_044255226.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_044254224.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044272810.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044271532.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044269153.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044259633.1	12	Reactome: R-HSA-75893;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-193692	"TNF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR"
XP_044252952.1	11	MetaCyc: PWY-6549;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2	"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism"
XP_044255954.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044267536.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_044264865.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-383280;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_044259526.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044254091.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6	"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_044265424.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044260496.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946	"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants"
XP_044270462.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes"
XP_044261983.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044266260.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044263439.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_044252528.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_044266545.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044267049.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_044258599.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044269031.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1	"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism"
XP_044255134.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_044264348.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044263626.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044265172.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-532668;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Neddylation";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome"
XP_044262008.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_044266691.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_044271116.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044268885.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044272551.1	8	KEGG: 00240+3.5.4.5;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-6556;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I"
XP_044264989.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_044267461.1	5	MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044265194.1	4	Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144	"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_044264563.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044256148.1	11	Reactome: R-HSA-3214858;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"RMTs methylate histone arginines";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044257156.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044265265.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_044259715.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044264311.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_044259380.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044260934.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044268248.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044254269.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway"
XP_044266400.1	11	Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-5913	"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)"
XP_044252776.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044267236.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_044257811.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044262205.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044253111.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044257012.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044259516.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_044264153.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044252890.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044269875.1	4	MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_044261988.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044253470.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044259370.1	6	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)"
XP_044265291.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044268404.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-6453	"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis"
XP_044262373.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-176407	"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_044269783.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044261601.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044266590.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044257888.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044269846.1	11	Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972	"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_044258817.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044261770.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081	"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling"
XP_044253729.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_044254298.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_044270579.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_044262796.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_044255206.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044253368.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044260514.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044257591.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044252935.1	11	Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism"
XP_044263020.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044265732.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269168.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044254469.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044264194.1	17	Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-3270619;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-1834949	"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"IRF3-mediated induction of type I IFN";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Cytosolic sensors of pathogen-associated DNA"
XP_044261103.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044252512.1	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_044272757.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044266958.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606	"NOTCH3 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044263361.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044260376.1	7	Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-7782;MetaCyc: PWY-3385;MetaCyc: PWY-7886	"Synthesis of PE";"Synthesis of PC";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_044272116.1	5	MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
XP_044267214.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044255673.1	179	Reactome: R-HSA-5357956;Reactome: R-HSA-5675221;Reactome: R-HSA-3134975;Reactome: R-HSA-6781827;Reactome: R-HSA-1358803;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-174178;Reactome: R-HSA-1236382;Reactome: R-HSA-5696394;Reactome: R-HSA-937042;Reactome: R-HSA-195253;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-937039;Reactome: R-HSA-5610783;Reactome: R-HSA-110320;Reactome: R-HSA-5654733;Reactome: R-HSA-2894862;Reactome: R-HSA-209543;Reactome: R-HSA-912631;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-8849469;Reactome: R-HSA-8941858;Reactome: R-HSA-6804760;Reactome: R-HSA-5684264;Reactome: R-HSA-211733;Reactome: R-HSA-5696395;Reactome: R-HSA-8856828;Reactome: R-HSA-5696397;Reactome: R-HSA-5675482;Reactome: R-HSA-8939236;Reactome: R-HSA-72706;Reactome: R-HSA-3785653;Reactome: R-HSA-8948747;Reactome: R-HSA-168927;Reactome: R-HSA-532668;Reactome: R-HSA-917729;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-1253288;Reactome: R-HSA-9613829;Reactome: R-HSA-5654732;Reactome: R-HSA-187577;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-69541;Reactome: R-HSA-174184;Reactome: R-HSA-9013507;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-975163;Reactome: R-HSA-2173788;Reactome: R-HSA-937072;Reactome: R-HSA-3322077;Reactome: R-HSA-5689901;Reactome: R-HSA-69231;Reactome: R-HSA-5656121;Reactome: R-HSA-6791226;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-445989;Reactome: R-HSA-174084;Reactome: R-HSA-5205685;Reactome: R-HSA-168928;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-182971;Reactome: R-HSA-8866652;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-174048;Reactome: R-HSA-937041;Reactome: R-HSA-1234176;Reactome: R-HSA-2565942;Reactome: R-HSA-3769402;Reactome: R-HSA-68827;Reactome: R-HSA-9014325;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-2691232;Reactome: R-HSA-5696400;Reactome: R-HSA-5689896;Reactome: R-HSA-1169408;Reactome: R-HSA-175474;Reactome: R-HSA-2467813;Reactome: R-HSA-1799339;Reactome: R-HSA-5607761;Reactome: R-HSA-110312;Reactome: R-HSA-156827;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5655862;Reactome: R-HSA-2122948;Reactome: R-HSA-75815;Reactome: R-HSA-9633012;Reactome: R-HSA-2644606;Reactome: R-HSA-9033241;Reactome: R-HSA-9615710;Reactome: R-HSA-209560;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-975144;Reactome: R-HSA-5362768;Reactome: R-HSA-8866654;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-975957;Reactome: R-HSA-382556;Reactome: R-HSA-5357905;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-5693607;Reactome: R-HSA-975110;Reactome: R-HSA-6807004;Reactome: R-HSA-400253;Reactome: R-HSA-2408557;Reactome: R-HSA-2871837;Reactome: R-HSA-1295596;Reactome: R-HSA-5610780;Reactome: R-HSA-901032;Reactome: R-HSA-179409;Reactome: R-HSA-2173791;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-1169091;Reactome: R-HSA-6783310;Reactome: R-HSA-5656169;Reactome: R-HSA-8876493;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-162588;Reactome: R-HSA-6782135;Reactome: R-HSA-72689;Reactome: R-HSA-9637628;Reactome: R-HSA-2173795;Reactome: R-HSA-192823;Reactome: R-HSA-174490;Reactome: R-HSA-69017;Reactome: R-HSA-917937;Reactome: R-HSA-5668541;Reactome: R-HSA-4641263;Reactome: R-HSA-4641257;Reactome: R-HSA-5654727;Reactome: R-HSA-201681;Reactome: R-HSA-5607764;Reactome: R-HSA-156902;Reactome: R-HSA-5693565;Reactome: R-HSA-5689877;Reactome: R-HSA-168638;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-2173796;Reactome: R-HSA-6804757;Reactome: R-HSA-205043;Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-936964;Reactome: R-HSA-6781823;Reactome: R-HSA-2559585;Reactome: R-HSA-2672351;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323	"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of MAPK pathway";"Regulation of innate immune responses to cytosolic DNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Downregulation of ERBB2:ERBB3 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"DNA Damage Recognition in GG-NER";"IRAK2 mediated activation of TAK1 complex";"Degradation of beta-catenin by the destruction complex";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"IRAK1 recruits IKK complex";"Degradation of GLI2 by the proteasome";"Translesion Synthesis by POLH";"Negative regulation of FGFR4 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"p75NTR recruits signalling complexes";"Regulation of signaling by CBL";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of RUNX3 expression and activity";"Regulation of TP53 Activity through Methylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Formation of Incision Complex in GG-NER";"Clathrin-mediated endocytosis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of necroptotic cell death";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Myoclonic epilepsy of Lafora";"Regulation of PTEN localization";"TICAM1, RIP1-mediated IKK complex recruitment";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Neddylation";"Asymmetric localization of PCP proteins";"Downregulation of ERBB4 signaling";"Chaperone Mediated Autophagy";"Negative regulation of FGFR3 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"Stabilization of p53";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downregulation of TGF-beta receptor signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Glycogen synthesis";"Metalloprotease DUBs";"Cyclin D associated events in G1";"Translesion synthesis by POLI";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Pink/Parkin Mediated Mitophagy";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"EGFR downregulation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"APC/C:Cdc20 mediated degradation of Cyclin B";"IKK complex recruitment mediated by RIP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PLK1 Activity at G2/M Transition";"Deactivation of the beta-catenin transactivating complex";"CDT1 association with the CDC6:ORC:origin complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Dual Incision in GG-NER";"Ovarian tumor domain proteases";"ISG15 antiviral mechanism";"Assembly Of The HIV Virion";"Separation of Sister Chromatids";"SRP-dependent cotranslational protein targeting to membrane";"Dectin-1 mediated noncanonical NF-kB signaling";"Translesion synthesis by REV1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of PTEN stability and activity";"UCH proteinases";"Translesion synthesis by POLK";"Activated NOTCH1 Transmits Signal to the Nucleus";"Ubiquitin-dependent degradation of Cyclin D";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Peroxisomal protein import";"Late endosomal microautophagy";"NF-kB is activated and signals survival";"Hedgehog 'on' state";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"E3 ubiquitin ligases ubiquitinate target proteins";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ABC-family proteins mediated transport";"Regulation of TNFR1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Processing of DNA double-strand break ends";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Negative regulation of MET activity";"Circadian Clock";"Selenocysteine synthesis";"FCERI mediated NF-kB activation";"Spry regulation of FGF signaling";"Degradation of GLI1 by the proteasome";"ER Quality Control Compartment (ERQC)";"APC-Cdc20 mediated degradation of Nek2A";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"Activation of NF-kappaB in B cells";"Fanconi Anemia Pathway";"Termination of translesion DNA synthesis";"InlA-mediated entry of Listeria monocytogenes into host cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Budding and maturation of HIV virion";"Dual incision in TC-NER";"Formation of a pool of free 40S subunits";"Modulation by Mtb of host immune system";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Viral mRNA Translation";"Membrane binding and targetting of GAG proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Iron uptake and transport";"TNFR2 non-canonical NF-kB pathway";"Regulation of FZD by ubiquitination";"Degradation of AXIN";"Negative regulation of FGFR2 signaling";"TCF dependent signaling in response to WNT";"CLEC7A (Dectin-1) signaling";"Peptide chain elongation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Josephin domain DUBs";"NOD1/2 Signaling Pathway";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of TP53 Degradation";"NRIF signals cell death from the nucleus";"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Formation of TC-NER Pre-Incision Complex";"Oncogene Induced Senescence";"Stimuli-sensing channels";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling"
XP_044268541.1	5	MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_044252297.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_044263818.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044265834.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_044258578.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation"
XP_044255930.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044255238.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_044259820.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_044265263.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044258724.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_044269410.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_044252314.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_044256115.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_044271044.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_044272365.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_044263572.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_044272378.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_044270390.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection"
XP_044270517.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_044259890.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4615885	"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins"
XP_044259982.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_044267775.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_044262565.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_044254398.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044253654.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_044255916.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_044270171.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044267751.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044271524.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044263285.1	52	Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-5250924;Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"B-WICH complex positively regulates rRNA expression";"MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044268297.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-176187	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress"
XP_044264725.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044252709.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044266108.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_044265129.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044253293.1	8	Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Dual incision in TC-NER"
XP_044272390.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044267303.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044254352.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_044271758.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044268536.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_044271066.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044253724.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044260583.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044272186.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044270394.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044271221.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044271727.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_044262589.1	5	KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;MetaCyc: PWY-7918	"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)"
XP_044265053.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-7863;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843	"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism"
XP_044258826.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_044270185.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044261992.1	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_044269477.1	4	MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_044259980.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_044271617.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_044256104.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044259502.1	2	Reactome: R-HSA-3785653;Reactome: R-HSA-3322077	"Myoclonic epilepsy of Lafora";"Glycogen synthesis"
XP_044271913.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044254321.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044266057.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044258644.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_044259751.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_044270559.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_044255276.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044253278.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044254414.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044266656.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_044255400.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044272709.1	10	Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23	"MPS VII - Sly syndrome";"Neutrophil degranulation";"Other glycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism"
XP_044270082.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_044256053.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044258855.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723	"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Rubisco shunt"
XP_044262922.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_044268609.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044267183.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044270869.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_044257465.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044268238.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044255751.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_044267139.1	5	Reactome: R-HSA-2173789;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport";"UCH proteinases";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_044261745.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044265338.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044269148.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044264703.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase"
XP_044268342.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_044254146.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_044266542.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human papillomavirus infection"
XP_044269389.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044255359.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044256198.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044271733.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_044253613.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044259289.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_044265000.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044257998.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044268162.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044253970.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044255278.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044270112.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_044259494.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044263633.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044260628.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044272137.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044259964.1	6	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism"
XP_044258489.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_044270422.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events"
XP_044272280.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_044263143.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_044262435.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_044263305.1	11	MetaCyc: PWY-7560;MetaCyc: PWY-6859;MetaCyc: PWY-6174;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7102;MetaCyc: PWY-6383;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-5123;MetaCyc: PWY-7391;MetaCyc: PWY-7524	"Methylerythritol phosphate pathway II";"All-trans-farnesol biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Trans, trans-farnesyl diphosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)"
XP_044261792.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_044272187.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044268584.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_044258323.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_044269200.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_044254844.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044272662.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_044267840.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044259722.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044257275.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044263785.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044265765.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044261113.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_044269530.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044270017.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_044262308.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044258103.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_044261179.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_044267554.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044253407.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044256812.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044261032.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044265632.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044255796.1	14	MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-6728;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Butanoate metabolism"
XP_044258291.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044260291.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044268295.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_044252921.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044269446.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_044271420.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044261029.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044266536.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_044270093.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044254499.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044264064.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044262268.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044267936.1	10	MetaCyc: PWY-5022;Reactome: R-HSA-916853;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-4321;MetaCyc: PWY-6537;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19	"4-aminobutanoate degradation V";"Degradation of GABA";"Butanoate metabolism";"4-aminobutanoate degradation I";"L-glutamate degradation IV";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"beta-Alanine metabolism";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism"
XP_044262335.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_044269933.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_044260100.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_044253038.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044259493.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_044272293.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044264561.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044264037.1	3	Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_044267347.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044256580.1	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268	"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_044267193.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044271504.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511	"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Meiotic recombination";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"HSF1 activation"
XP_044263363.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044256141.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_044254151.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044265433.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044253050.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_044253897.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_044267844.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044262206.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044262618.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044271314.1	3	KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism"
XP_044254076.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044266136.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_044260981.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044261394.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_044256085.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_044255459.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044268109.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_044252573.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044266520.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_044262267.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044257805.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044264756.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis"
XP_044253963.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_044253668.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_044269159.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044264892.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044271841.1	9	KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52	"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_044267940.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044257127.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_044264599.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER"
XP_044258766.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044256212.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism"
XP_044263166.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_044262718.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_044262735.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044256111.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044266687.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_044257276.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044253789.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044267170.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044256093.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044254827.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685	"Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species"
XP_044257018.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_044263521.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044261320.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_044265301.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_044261590.1	12	MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway"
XP_044254651.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044266574.1	8	MetaCyc: PWY-5789;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-6142	"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_044252975.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044258794.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044262802.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044259617.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044266435.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_044260203.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044265822.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-73980;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-76066;Reactome: R-HSA-168325	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis"
XP_044258159.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044266421.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044254995.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_044265283.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044272828.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-8001	"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_044255460.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044262327.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044252525.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism"
XP_044254597.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_044272545.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044256388.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_044265891.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_044264268.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044265918.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_044259937.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044266157.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-163359	"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon signaling in metabolic regulation"
XP_044271621.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044265396.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"rRNA processing in the mitochondrion"
XP_044262876.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044256806.1	16	MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5749	"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Itaconate degradation"
XP_044255781.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044258330.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_044257217.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044271261.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044253383.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044265008.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_044271440.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044271463.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_044269164.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_044254357.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_044254460.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044260409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044256549.1	7	MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Neolacto-series glycosphingolipids biosynthesis"
XP_044266426.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044252726.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_044270147.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs"
XP_044265787.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044256784.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044263420.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044266785.1	4	Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_044260429.1	7	Reactome: R-HSA-1483226;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11	"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_044255919.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044272036.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044256894.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044259626.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_044269281.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044267213.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_044270491.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_044259413.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044262353.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044261841.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Neddylation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport"
XP_044263478.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated"
XP_044271546.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840	"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Rho GTPase cycle"
XP_044257389.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044268542.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Processing of DNA double-strand break ends"
XP_044267431.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044255316.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044262044.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044264081.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_044268980.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044255888.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_044253588.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_044261519.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044252887.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044260411.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044272208.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_044266312.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_044264119.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_044266151.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044262812.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044269044.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044263873.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044256872.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044253801.1	13	Reactome: R-HSA-6802946;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1	"Signaling by moderate kinase activity BRAF mutants";"Human cytomegalovirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Thermogenesis"
XP_044255429.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_044268578.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_044256112.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044259396.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_044261426.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044253532.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_044256773.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_044267002.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_044271961.1	16	Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-196025;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-5140745	"Recycling pathway of L1";"Clathrin-mediated endocytosis";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Formation of annular gap junctions";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_044258388.1	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_044252299.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_044265168.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044261805.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_044253833.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044260455.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044268332.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_044271940.1	44	KEGG: 04150+2.7.11.24;Reactome: R-HSA-8940973;Reactome: R-HSA-450341;Reactome: R-HSA-9649948;Reactome: R-HSA-5663213;Reactome: R-HSA-5654733;Reactome: R-HSA-6802946;Reactome: R-HSA-5674499;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-202670;Reactome: R-HSA-162658;Reactome: R-HSA-170968;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-8943724;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-5673001;Reactome: R-HSA-1295596;Reactome: R-HSA-881907;Reactome: R-HSA-112409;Reactome: R-HSA-2029482;Reactome: R-HSA-5674135;Reactome: R-HSA-445144;Reactome: R-HSA-8939211;Reactome: R-HSA-74749;Reactome: R-HSA-6802955;Reactome: R-HSA-3371453;Reactome: R-HSA-5675221;Reactome: R-HSA-198753;Reactome: R-HSA-375165;Reactome: R-HSA-456926;Reactome: R-HSA-879415;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-444257;Reactome: R-HSA-9635465;Reactome: R-HSA-5668599;Reactome: R-HSA-2871796;Reactome: R-HSA-982772	"mTOR signaling pathway";"RUNX2 regulates osteoblast differentiation";"Activation of the AP-1 family of transcription factors";"Signaling downstream of RAS mutants";"RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR4 signaling";"Signaling by moderate kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"ERKs are inactivated";"Golgi Cisternae Pericentriolar Stack Reorganization";"Frs2-mediated activation";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Regulation of PTEN gene transcription";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"RAF/MAP kinase cascade";"Spry regulation of FGF signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"RAF-independent MAPK1/3 activation";"Regulation of actin dynamics for phagocytic cup formation";"MAP2K and MAPK activation";"Signal transduction by L1";"ESR-mediated signaling";"Signal attenuation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of HSF1-mediated heat shock response";"Negative regulation of MAPK pathway";"ERK/MAPK targets";"NCAM signaling for neurite out-growth";"Thrombin signalling through proteinase activated receptors (PARs)";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RSK activation";"Suppression of apoptosis";"RHO GTPases Activate NADPH Oxidases";"FCERI mediated MAPK activation";"Growth hormone receptor signaling"
XP_044253273.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044252602.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_044261413.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044257371.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044265282.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044263381.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044268148.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_044271643.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_044258370.1	5	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_044252606.1	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Formation of apoptosome"
XP_044256935.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044270902.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044263145.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_044253584.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044263011.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_044263362.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044271039.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044254470.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044258333.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_044253579.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_044256131.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_044265381.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044257088.1	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_044272616.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_044262023.1	12	Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-6936;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-7901	"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine"
XP_044256681.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_044263687.1	7	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism"
XP_044272087.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_044253236.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_044252918.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044269447.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_044264017.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_044254598.1	7	MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23	"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_044266386.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044253349.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_044256167.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044264752.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044258752.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044265740.1	10	Reactome: R-HSA-4719377;MetaCyc: PWY-7661;Reactome: R-HSA-162699;Reactome: R-HSA-913709;Reactome: R-HSA-4719360;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;Reactome: R-HSA-4717374	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"O-linked glycosylation of mucins";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_044272387.1	10	KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695	"Glycosaminoglycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation"
XP_044254652.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044255810.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044262923.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_044257930.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044268538.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_044252916.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044267880.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_044271620.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044263344.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044266376.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044262877.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044265270.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_044260290.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044255653.1	33	Reactome: R-HSA-933542;Reactome: R-HSA-975155;Reactome: R-HSA-975163;Reactome: R-HSA-937042;Reactome: R-HSA-209560;Reactome: R-HSA-937072;Reactome: R-HSA-6811558;Reactome: R-HSA-975144;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-937039;Reactome: R-HSA-209543;Reactome: R-HSA-5689880;Reactome: R-HSA-975138;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-205043;Reactome: R-HSA-975110;Reactome: R-HSA-168927;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-166058;Reactome: R-HSA-9014325;Reactome: R-HSA-937041;Reactome: R-HSA-193692;Reactome: R-HSA-5689896;Reactome: R-HSA-9645460;Reactome: R-HSA-933541;Reactome: R-HSA-975871;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;MetaCyc: PWY-7511	"TRAF6 mediated NF-kB activation";"MyD88 dependent cascade initiated on endosome";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex";"NF-kB is activated and signals survival";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"IRAK1 recruits IKK complex";"p75NTR recruits signalling complexes";"Ub-specific processing proteases";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"NRIF signals cell death from the nucleus";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IKK complex recruitment mediated by RIP1";"Regulated proteolysis of p75NTR";"Ovarian tumor domain proteases";"Alpha-protein kinase 1 signaling pathway";"TRAF6 mediated IRF7 activation";"MyD88 cascade initiated on plasma membrane";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"Protein ubiquitination"
XP_044272362.1	17	Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-1169091;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-5689880;Reactome: R-HSA-4086398	"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"Downstream TCR signaling";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of NF-kappaB in B cells";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"Ub-specific processing proteases";"Ca2+ pathway"
XP_044259515.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_044269335.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044252742.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_044271195.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044259836.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_044258608.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044256348.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168333	"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_044265281.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_044269545.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044267304.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044258412.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_044264111.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_044258841.1	3	KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_044270784.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044258173.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044267615.1	18	MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6642	"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation"
XP_044258715.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_044262341.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044270026.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131	"Collagen degradation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR"
XP_044267513.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_044256491.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044256636.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044272407.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_044270304.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Thermogenesis"
XP_044264728.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044258888.1	4	Reactome: R-HSA-6787450;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_044254637.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044252341.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044263770.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_044265803.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_044262174.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-5667;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA"
XP_044253831.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044258878.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044257741.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044271144.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044268409.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044272071.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_044263122.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044258272.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044255047.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_044270317.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_044271468.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044254227.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044261843.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
XP_044261933.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51	"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_044258125.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932	"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB"
XP_044271185.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044252886.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044256759.1	5	Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_044263012.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_044266401.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044253549.1	83	Reactome: R-HSA-210993;Reactome: R-HSA-512988;Reactome: R-HSA-8875360;Reactome: R-HSA-375165;Reactome: R-HSA-5654699;Reactome: R-HSA-5654700;Reactome: R-HSA-1257604;Reactome: R-HSA-5654704;Reactome: R-HSA-5654693;Reactome: R-HSA-2871796;Reactome: R-HSA-8875656;Reactome: R-HSA-5655302;Reactome: R-HSA-1236382;Reactome: R-HSA-391160;Reactome: R-HSA-9634285;Reactome: R-HSA-9645135;Reactome: R-HSA-74749;Reactome: R-HSA-8853659;Reactome: R-HSA-389359;Reactome: R-HSA-74751;Reactome: R-HSA-2219530;Reactome: R-HSA-5654726;Reactome: R-HSA-5654688;Reactome: R-HSA-8851805;Reactome: R-HSA-5654732;Reactome: R-HSA-167044;Reactome: R-HSA-9664565;Reactome: R-HSA-8853338;Reactome: R-HSA-1295596;Reactome: R-HSA-1839117;Reactome: R-HSA-6807004;Reactome: R-HSA-1963640;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-8856828;Reactome: R-HSA-5654719;Reactome: R-HSA-109704;Reactome: R-HSA-912631;Reactome: R-HSA-5654733;Reactome: R-HSA-2179392;Reactome: R-HSA-1250196;Reactome: R-HSA-2428933;Reactome: R-HSA-5654727;Reactome: R-HSA-2424491;Reactome: R-HSA-180292;Reactome: R-HSA-5654706;Reactome: R-HSA-8875555;Reactome: R-HSA-5637810;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-9027284;Reactome: R-HSA-8853334;Reactome: R-HSA-5654689;Reactome: R-HSA-2029482;Reactome: R-HSA-1963642;Reactome: R-HSA-2871809;Reactome: R-HSA-5655253;Reactome: R-HSA-9607240;Reactome: R-HSA-9028731;Reactome: R-HSA-8865999;Reactome: R-HSA-5654710;Reactome: R-HSA-5655291;Reactome: R-HSA-112412;Reactome: R-HSA-180336;Reactome: R-HSA-9028335;Reactome: R-HSA-8851907;Reactome: R-HSA-186763;Reactome: R-HSA-8856825;Reactome: R-HSA-8983432;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712;Reactome: R-HSA-182971;Reactome: R-HSA-354194;Reactome: R-HSA-5654720;Reactome: R-HSA-9034864;Reactome: R-HSA-2730905;Reactome: R-HSA-179812;Reactome: R-HSA-9026519;Reactome: R-HSA-1433559;Reactome: R-HSA-1250347;Reactome: R-HSA-5654695;Reactome: R-HSA-5663213;Reactome: R-HSA-983695	"Tie2 Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"NCAM signaling for neurite out-growth";"SHC-mediated cascade:FGFR2";"FRS-mediated FGFR2 signaling";"PIP3 activates AKT signaling";"SHC-mediated cascade:FGFR3";"FRS-mediated FGFR1 signaling";"FCERI mediated MAPK activation";"MET receptor recycling";"Signaling by FGFR1 in disease";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signal regulatory protein family interactions";"Constitutive Signaling by Overexpressed ERBB2";"STAT5 Activation";"Signal attenuation";"RET signaling";"CD28 dependent Vav1 pathway";"Insulin receptor signalling cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR1 signaling";"SHC-mediated cascade:FGFR1";"MET activates RAS signaling";"Negative regulation of FGFR3 signaling";"Signalling to RAS";"Signaling by ERBB2 KD Mutants";"Signaling by FGFR3 point mutants in cancer";"Spry regulation of FGF signaling";"Signaling by cytosolic FGFR1 fusion mutants";"Negative regulation of MET activity";"GRB2 events in ERBB2 signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"Clathrin-mediated endocytosis";"SHC-mediated cascade:FGFR4";"PI3K Cascade";"Regulation of signaling by CBL";"Negative regulation of FGFR4 signaling";"EGFR Transactivation by Gastrin";"SHC1 events in ERBB2 signaling";"SHC-related events triggered by IGF1R";"Negative regulation of FGFR2 signaling";"DAP12 signaling";"GAB1 signalosome";"FRS-mediated FGFR3 signaling";"MET activates RAP1 and RAC1";"Constitutive Signaling by EGFRvIII";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"Erythropoietin activates RAS";"Signaling by FGFR3 fusions in cancer";"PI-3K cascade:FGFR1";"Regulation of actin dynamics for phagocytic cup formation";"PI3K events in ERBB2 signaling";"FCERI mediated Ca+2 mobilization";"Signaling by FGFR2 in disease";"FLT3 Signaling";"Activated NTRK2 signals through FRS2 and FRS3";"MET activates PTPN11";"PI-3K cascade:FGFR3";"Signaling by FGFR4 in disease";"SOS-mediated signalling";"SHC1 events in EGFR signaling";"Activated NTRK2 signals through PI3K";"MET activates PI3K/AKT signaling";"Downstream signal transduction";"Cargo recognition for clathrin-mediated endocytosis";"Interleukin-15 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling";"EGFR downregulation";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI-3K cascade:FGFR4";"Activated NTRK3 signals through RAS";"Role of LAT2/NTAL/LAB on calcium mobilization";"GRB2 events in EGFR signaling";"Activated NTRK2 signals through RAS";"Regulation of KIT signaling";"SHC1 events in ERBB4 signaling";"PI-3K cascade:FGFR2";"RHO GTPases Activate WASPs and WAVEs";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_044272418.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_044255851.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044257003.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044261643.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_044257898.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins"
XP_044260092.1	3	Reactome: R-HSA-73772;Reactome: R-HSA-8953750;Reactome: R-HSA-427389	"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_044262209.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044271831.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044268699.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_044271305.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_044256022.1	30	Reactome: R-HSA-199418;Reactome: R-HSA-198323;Reactome: R-HSA-389357;Reactome: R-HSA-198693;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8941332;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-111447;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-9634638;Reactome: R-HSA-69656;Reactome: R-HSA-5674400;Reactome: R-HSA-211163;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-8948751;Reactome: R-HSA-8876198;Reactome: R-HSA-1358803;Reactome: R-HSA-5218920;Reactome: R-HSA-9614399;Reactome: R-HSA-389513;Reactome: R-HSA-6804759;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804758	"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the cytosol";"CD28 dependent PI3K/Akt signaling";"AKT phosphorylates targets in the nucleus";"Relaxin signaling pathway";"RUNX2 regulates genes involved in cell migration";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"Activation of BAD and translocation to mitochondria";"Thermogenesis";"Cyclin E associated events during G1/S transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A:Cdk2-associated events at S phase entry";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT-mediated inactivation of FOXO1A";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Regulation of PTEN stability and activity";"RAB GEFs exchange GTP for GDP on RABs";"Downregulation of ERBB2:ERBB3 signaling";"VEGFR2 mediated vascular permeability";"Regulation of localization of FOXO transcription factors";"CTLA4 inhibitory signaling";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of TP53 Degradation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Acetylation"
XP_044264908.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-205043	"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus"
XP_044270518.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_044264795.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044263665.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900	"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_044260416.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044256011.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044272512.1	14	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-8854518;Reactome: R-HSA-141444	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044272526.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044252734.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_044255258.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044260101.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_044256926.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_044267828.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044262441.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_044263224.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044255585.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044265383.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044256239.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044261978.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044270188.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044262452.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_044252961.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044262395.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"PPARA activates gene expression";"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_044263204.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044269840.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044268341.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_044255375.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-400253	"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock"
XP_044264328.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044272070.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_044260780.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_044258862.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_044270991.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044256584.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044272281.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_044271419.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044255955.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044265984.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_044262241.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044265294.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044272374.1	15	MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221	"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Pyruvate metabolism";"Glycolysis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_044265378.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044252680.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044261730.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044254630.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107	"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_044261928.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_044269589.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044252944.1	11	Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964	"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II"
XP_044255746.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044271518.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044262956.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044264289.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044269022.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044257020.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044260142.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_044264063.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044259869.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_044257110.1	11	Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-975634	"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport"
XP_044257045.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_044256899.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044266416.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044253505.1	16	Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580	"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Oxidative Stress Induced Senescence"
XP_044262544.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044260199.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044258610.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044260976.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044262135.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_044264355.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044259578.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044264798.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044254648.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_044252408.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044266152.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044268512.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044257770.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044266454.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744	"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation"
XP_044260926.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044256895.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044263387.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044272635.1	9	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"mTOR signalling";"Macroautophagy"
XP_044268774.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_044256242.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_044254684.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_044266066.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044255802.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044261313.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_044259541.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_044269205.1	6	KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346	"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_044269309.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044272754.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression"
XP_044253872.1	7	Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7039	"Synthesis of PG";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule"
XP_044255299.1	5	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_044253877.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_044263316.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_044266481.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_044260865.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks"
XP_044260147.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044261277.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_044264383.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044270319.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044267330.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044255645.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_044254488.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044272213.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044258457.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044258099.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001	"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade"
XP_044257388.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network"
XP_044256750.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_044254902.1	33	Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-180746	"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein"
XP_044254188.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_044268406.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_044271119.1	8	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6783310;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Fanconi Anemia Pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044264351.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044270089.1	29	Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167172	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome"
XP_044252621.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_044271038.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044266313.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_044267469.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044269574.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044259821.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_044264737.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_044266540.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044253403.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044255628.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044267314.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044255001.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_044267524.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044265919.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_044270179.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_044272267.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system"
XP_044260362.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044256983.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044263909.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044258134.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_044270088.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_044255044.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044261184.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_044269163.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044256613.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_044253279.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044253289.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_044263183.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_044267188.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_044272062.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_044257673.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044261231.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_044272069.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_044260485.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044267168.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044269451.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_044260424.1	4	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism"
XP_044252653.1	14	KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2201;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661	"Cyanoamino acid metabolism";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I"
XP_044261243.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044268236.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6791226;Reactome: R-HSA-6784531;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus";"Protein ubiquitination"
XP_044263146.1	5	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310	"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway"
XP_044253552.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_044257849.1	8	KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1	"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis"
XP_044265679.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_044252567.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_044267786.1	16	Reactome: R-HSA-9664565;Reactome: R-HSA-1251985;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1963640;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631	"Signaling by ERBB2 KD Mutants";"Nuclear signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility"
XP_044267683.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_044259114.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044266670.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044270458.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044254950.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044263266.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_044265183.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_044268407.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_044272041.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_044269154.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044257040.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_044269956.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044266099.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_044254865.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044269850.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044257406.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_044253049.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044266061.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044262688.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044256968.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044271277.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044260907.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_044255630.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044265382.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044261780.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044262201.1	10	Reactome: R-HSA-69205;MetaCyc: PWY-7187;MetaCyc: PWY-7199;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-3841;MetaCyc: PWY-7198	"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_044259979.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044261530.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044271405.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_044268808.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044272237.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167161	"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation"
XP_044259525.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044256423.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_044256864.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_044261098.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044272829.1	10	MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism"
XP_044256930.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_044267429.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044253804.1	13	KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Signaling by moderate kinase activity BRAF mutants";"Relaxin signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Thermogenesis"
XP_044264391.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436	"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044261572.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044259067.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044257532.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044261489.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_044268290.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_044252724.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_044255581.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044256217.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_044257443.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044256954.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044252814.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044269484.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044258979.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_044256466.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_044258540.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_044260487.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_044255243.1	20	Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual Incision in GG-NER"
XP_044254083.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044257903.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044257662.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044271991.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_044271840.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"T cell receptor signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_044261708.1	32	Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167172	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome"
XP_044265730.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044260811.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044271386.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044271517.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-68962	"HSF1 activation";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Meiotic recombination";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex"
XP_044263789.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_044267151.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_044269602.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044269475.1	4	MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26	"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_044263469.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_044263231.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_044259563.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044262306.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_044270344.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044272291.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_044261256.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044256367.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_044266158.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-8964616	"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"G-protein activation";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42"
XP_044259957.1	7	MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_044253719.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044260182.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044269167.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044265189.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044265069.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821	"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"D-galactose detoxification"
XP_044256482.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_044264239.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_044271206.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044268744.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044253507.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519	"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Estrogen-dependent gene expression"
XP_044259760.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829	"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_044257687.1	5	Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_044262917.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis";"Rubisco shunt";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)"
XP_044260925.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044260169.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044256253.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044268579.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_044269785.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_044254744.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044268869.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044255311.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044264097.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044256928.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_044261878.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_044265603.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044261692.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044268821.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_044260582.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044261383.1	10	MetaCyc: PWY-5844;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5890;MetaCyc: PWY-5895;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163	"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_044254354.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_044258270.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044260330.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044262266.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044261534.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044263658.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044263128.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_044263622.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-432040	"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_044258577.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_044269613.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling"
XP_044260956.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_044265118.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044256480.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_044258206.1	6	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors"
XP_044261395.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044256025.1	9	MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-1855204	"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol"
XP_044262336.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_044261275.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_044267242.1	5	MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044265725.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044259993.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_044257945.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044272497.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044260819.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044269513.1	17	Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174184	"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_044270320.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044257842.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044263171.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044258790.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_044262300.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044267886.1	17	MetaCyc: PWY-4202;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1	"Arsenate detoxification I (mammalian)";"Purine catabolism";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine salvage";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II"
XP_044254368.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_044256422.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044266111.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044259847.1	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
XP_044258043.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_044270612.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-114516	"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation"
XP_044259099.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation"
XP_044270754.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044262397.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation"
XP_044256898.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044270114.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_044270419.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044253272.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044271593.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044253583.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_044258791.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_044257973.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_044254040.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_044255106.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_044271460.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044260758.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044259366.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044269263.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_044268445.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237	"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2"
XP_044263623.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044254494.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044258211.1	6	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_044259090.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-6824	"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis"
XP_044259391.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism"
XP_044266782.1	21	MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7219;MetaCyc: PWY-7221;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7205	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"CMP phosphorylation"
XP_044256137.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044268253.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044269124.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044260872.1	15	Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_044272073.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_044258208.1	6	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_044267736.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952	"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation"
XP_044267556.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_044265334.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044257575.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044257771.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3108214	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"HCMV Late Events";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins"
XP_044253800.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_044263523.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044265278.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044257158.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044255613.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044267455.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_044263062.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis"
XP_044254402.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044268284.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_044255618.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044258695.1	11	Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;Reactome: R-HSA-1632852;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137	"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"Macroautophagy";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system"
XP_044272167.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_044265409.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_044271130.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044263727.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_044264144.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_044272395.1	11	Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5663213	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs"
XP_044252904.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_044255213.1	6	KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7077	"Galactose metabolism";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation"
XP_044258885.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044271598.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044270025.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295	"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Collagen degradation";"MHC class II antigen presentation"
XP_044260679.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044256220.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_044270748.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044271622.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044268034.1	6	MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-6952	"Glycerol degradation I";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation"
XP_044269284.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_044269186.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044265926.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044272190.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044265557.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_044261114.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_044271205.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044266052.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_044270990.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044265140.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_044269071.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_044258836.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044264094.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044271129.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-140875	"Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation"
XP_044272825.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_044261919.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044257390.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044254972.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044270732.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044261071.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_044267116.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_044254520.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_044252589.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044269156.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044270975.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044259954.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044265230.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044260662.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236	"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_044253968.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044259789.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257016.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_044266641.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044261432.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044258108.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324	"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_044257449.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044266073.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044258140.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_044259828.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_044268431.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_044252766.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044256664.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044255946.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044260602.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_044268863.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_044257346.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044270294.1	24	Reactome: R-HSA-5218921;Reactome: R-HSA-165158;Reactome: R-HSA-2730905;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5625740;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-354192;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-444257;Reactome: R-HSA-114604	"VEGFR2 mediated cell proliferation";"Activation of AKT2";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Degradation";"RHO GTPases activate PKNs";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"PIP3 activates AKT signaling";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Integrin signaling";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"RSK activation";"GPVI-mediated activation cascade"
XP_044253769.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044263953.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044252407.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_044259912.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044265297.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044254500.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_044254330.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-3861;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8	"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism"
XP_044257350.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044259752.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044272498.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044257162.1	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5108;MetaCyc: PWY-6672;MetaCyc: PWY-7857;MetaCyc: PWY-7118;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis"
XP_044266918.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_044253029.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044264134.1	6	Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-114508	"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis"
XP_044258446.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044270355.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044270191.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_044270577.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_044257291.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485	"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ca2+ pathway";"Regulation of insulin secretion";"Ion homeostasis";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis"
XP_044260128.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044252534.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_044253937.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_044261925.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044255109.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_044256168.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044259368.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation"
XP_044268794.1	7	Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044266422.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_044267148.1	6	KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)"
XP_044267579.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044264138.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_044254360.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044266961.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_044255536.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044258325.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_044252797.1	10	KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-1722	"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_044268002.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;MetaCyc: PWY-7250	"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_044255257.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044269508.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044271637.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_044272301.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_044268388.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852	"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy"
XP_044271143.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044253176.1	17	Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169	"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis"
XP_044272525.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044258377.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044263663.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_044271685.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_044262783.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-350054	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway"
XP_044252287.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044267238.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044254710.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Transcription of the HIV genome"
XP_044254960.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-881907;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors"
XP_044271043.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_044260185.1	4	MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_044260004.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
XP_044254879.1	10	MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Inositol phosphate metabolism";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism"
XP_044259740.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_044269066.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044255775.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_044257385.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044266539.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044267245.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_044257919.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044272832.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_044268190.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044263206.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_044265747.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044272191.1	6	Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731	"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_044259721.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044255962.1	8	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044255318.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044260564.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044255455.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044260451.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044266780.1	21	MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7219;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7220	"CMP phosphorylation";"Thiamine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_044253409.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044266661.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044272226.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_044265731.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044259364.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_044254428.1	7	Reactome: R-HSA-4549356;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis"
XP_044254738.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_044257442.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044256105.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044264616.1	4	MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_044268120.1	3	KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle"
XP_044271531.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044267309.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade"
XP_044266273.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555	"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events"
XP_044263594.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044270094.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044257410.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_044257573.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044268244.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044252596.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044263175.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044255011.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044256554.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_044257631.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_044268550.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044259152.1	10	KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"RSK activation";"Thermogenesis";"Recycling pathway of L1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_044254397.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044269382.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_044269703.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_044270965.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044254880.1	10	KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-7003	"Inositol phosphate metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol"
XP_044260895.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044270820.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_044266699.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044268572.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_044268410.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_044264303.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_044260488.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_044266384.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_044259500.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044271600.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044252851.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_044271001.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044266381.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044256736.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044265806.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis"
XP_044272809.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044253802.1	13	Reactome: R-HSA-6802955;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Thermogenesis";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044253646.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-383280	"Circadian Clock";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway"
XP_044258284.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_044256091.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044263164.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_044260952.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_044268571.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_044258369.1	5	KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
XP_044260282.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_044263862.1	5	KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_044271587.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_044256721.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044252738.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_044252618.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044264066.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240	"Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism"
XP_044268298.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress"
XP_044263970.1	33	Reactome: R-HSA-674695;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-8939236;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044255384.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_044260749.1	10	MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;KEGG: 00710+2.7.2.3	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
XP_044260348.1	40	Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_044255989.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044266608.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044269723.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044264916.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044259850.1	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
XP_044261691.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_044269137.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_044260493.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948	"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants"
XP_044271783.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)"
XP_044253269.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044270739.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_044272596.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_044265330.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044266356.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_044264382.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044269020.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044261652.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis"
XP_044260014.1	182	Reactome: R-HSA-5696394;Reactome: R-HSA-1236382;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-72764;Reactome: R-HSA-937042;Reactome: R-HSA-195253;Reactome: R-HSA-937039;Reactome: R-HSA-5610783;Reactome: R-HSA-975956;Reactome: R-HSA-5357956;Reactome: R-HSA-6782210;Reactome: R-HSA-1358803;Reactome: R-HSA-3134975;Reactome: R-HSA-5675221;Reactome: R-HSA-6781827;Reactome: R-HSA-6804756;Reactome: R-HSA-174178;Reactome: R-HSA-917729;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-532668;Reactome: R-HSA-72702;Reactome: R-HSA-1253288;Reactome: R-HSA-5654732;Reactome: R-HSA-9613829;Reactome: R-HSA-187577;Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-2894862;Reactome: R-HSA-110320;Reactome: R-HSA-2559582;Reactome: R-HSA-8849469;Reactome: R-HSA-8941858;Reactome: R-HSA-209543;Reactome: R-HSA-2559580;Reactome: R-HSA-912631;Reactome: R-HSA-5696395;Reactome: R-HSA-8856828;Reactome: R-HSA-5696397;Reactome: R-HSA-6804760;Reactome: R-HSA-5684264;Reactome: R-HSA-211733;Reactome: R-HSA-72649;Reactome: R-HSA-8948747;Reactome: R-HSA-168927;Reactome: R-HSA-5675482;Reactome: R-HSA-3785653;Reactome: R-HSA-72706;Reactome: R-HSA-8939236;Reactome: R-HSA-3322077;Reactome: R-HSA-5689901;Reactome: R-HSA-69231;Reactome: R-HSA-937072;Reactome: R-HSA-72695;Reactome: R-HSA-5656121;Reactome: R-HSA-6791226;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9013507;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-69541;Reactome: R-HSA-2173788;Reactome: R-HSA-975163;Reactome: R-HSA-174048;Reactome: R-HSA-937041;Reactome: R-HSA-1234176;Reactome: R-HSA-8866652;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-9014325;Reactome: R-HSA-3769402;Reactome: R-HSA-2565942;Reactome: R-HSA-68827;Reactome: R-HSA-2691232;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-175474;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-1799339;Reactome: R-HSA-5689896;Reactome: R-HSA-5696400;Reactome: R-HSA-445989;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5205685;Reactome: R-HSA-8863795;Reactome: R-HSA-5678895;Reactome: R-HSA-168928;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-182971;Reactome: R-HSA-75815;Reactome: R-HSA-9633012;Reactome: R-HSA-5655862;Reactome: R-HSA-2122948;Reactome: R-HSA-9615710;Reactome: R-HSA-9033241;Reactome: R-HSA-209560;Reactome: R-HSA-2644606;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-975144;Reactome: R-HSA-5607761;Reactome: R-HSA-110312;Reactome: R-HSA-156827;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-400253;Reactome: R-HSA-6807004;Reactome: R-HSA-5610780;Reactome: R-HSA-901032;Reactome: R-HSA-2408557;Reactome: R-HSA-2871837;Reactome: R-HSA-1295596;Reactome: R-HSA-179409;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-2173791;Reactome: R-HSA-9645460;Reactome: R-HSA-5362768;Reactome: R-HSA-8866654;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-975957;Reactome: R-HSA-382556;Reactome: R-HSA-5357905;Reactome: R-HSA-5693607;Reactome: R-HSA-975110;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-2173795;Reactome: R-HSA-9637628;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-917937;Reactome: R-HSA-174490;Reactome: R-HSA-192823;Reactome: R-HSA-4641257;Reactome: R-HSA-4641263;Reactome: R-HSA-201681;Reactome: R-HSA-156902;Reactome: R-HSA-5607764;Reactome: R-HSA-5654727;Reactome: R-HSA-6783310;Reactome: R-HSA-1169091;Reactome: R-HSA-5656169;Reactome: R-HSA-8876493;Reactome: R-HSA-69601;Reactome: R-HSA-72689;Reactome: R-HSA-6782135;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-162588;Reactome: R-HSA-8856825;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-9646399;Reactome: R-HSA-936964;Reactome: R-HSA-6781823;Reactome: R-HSA-2559585;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-2672351;Reactome: R-HSA-168638;Reactome: R-HSA-5693565;Reactome: R-HSA-5689877;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-2173796;Reactome: R-HSA-450321;Reactome: R-HSA-205043	"DNA Damage Recognition in GG-NER";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex";"Degradation of beta-catenin by the destruction complex";"IRAK1 recruits IKK complex";"Degradation of GLI2 by the proteasome";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TNFR1-induced NFkappaB signaling pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of MAPK pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Activity through Phosphorylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Neddylation";"Asymmetric localization of PCP proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ribosomal scanning and start codon recognition";"Downregulation of ERBB4 signaling";"Negative regulation of FGFR3 signaling";"Chaperone Mediated Autophagy";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Translesion Synthesis by POLH";"Senescence-Associated Secretory Phenotype (SASP)";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of RUNX3 expression and activity";"p75NTR recruits signalling complexes";"Oxidative Stress Induced Senescence";"Regulation of signaling by CBL";"Formation of Incision Complex in GG-NER";"Clathrin-mediated endocytosis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Methylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Translation initiation complex formation";"Regulation of PTEN localization";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of necroptotic cell death";"Myoclonic epilepsy of Lafora";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Glycogen synthesis";"Metalloprotease DUBs";"Cyclin D associated events in G1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Formation of the ternary complex, and subsequently, the 43S complex";"Translesion synthesis by POLI";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Stabilization of p53";"Downregulation of TGF-beta receptor signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"APC/C:Cdc20 mediated degradation of Cyclin B";"IKK complex recruitment mediated by RIP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Deactivation of the beta-catenin transactivating complex";"Regulation of PLK1 Activity at G2/M Transition";"CDT1 association with the CDC6:ORC:origin complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Assembly Of The HIV Virion";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"SRP-dependent cotranslational protein targeting to membrane";"Ovarian tumor domain proteases";"Dual Incision in GG-NER";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Pink/Parkin Mediated Mitophagy";"Downregulation of ERBB2 signaling";"Defective CFTR causes cystic fibrosis";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"EGFR downregulation";"Ubiquitin-dependent degradation of Cyclin D";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translesion synthesis by POLK";"Activated NOTCH1 Transmits Signal to the Nucleus";"Late endosomal microautophagy";"Peroxisomal protein import";"NF-kB is activated and signals survival";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Hedgehog 'on' state";"G2/M Checkpoints";"Regulation of RAS by GAPs";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Translesion synthesis by REV1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of PTEN stability and activity";"UCH proteinases";"Circadian Clock";"Negative regulation of MET activity";"Degradation of GLI1 by the proteasome";"ER Quality Control Compartment (ERQC)";"Selenocysteine synthesis";"FCERI mediated NF-kB activation";"Spry regulation of FGF signaling";"APC-Cdc20 mediated degradation of Nek2A";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Alpha-protein kinase 1 signaling pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"E3 ubiquitin ligases ubiquitinate target proteins";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ABC-family proteins mediated transport";"Regulation of TNFR1 signaling";"Processing of DNA double-strand break ends";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Modulation by Mtb of host immune system";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Iron uptake and transport";"Membrane binding and targetting of GAG proteins";"Viral mRNA Translation";"Degradation of AXIN";"Regulation of FZD by ubiquitination";"TCF dependent signaling in response to WNT";"Peptide chain elongation";"CLEC7A (Dectin-1) signaling";"Negative regulation of FGFR2 signaling";"Fanconi Anemia Pathway";"Activation of NF-kappaB in B cells";"Termination of translesion DNA synthesis";"InlA-mediated entry of Listeria monocytogenes into host cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of a pool of free 40S subunits";"Dual incision in TC-NER";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Budding and maturation of HIV virion";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Aggrephagy";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Formation of TC-NER Pre-Incision Complex";"Oncogene Induced Senescence";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Stimuli-sensing channels";"NOD1/2 Signaling Pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Josephin domain DUBs";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NRIF signals cell death from the nucleus"
XP_044254716.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_044264247.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044259293.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_044253323.1	14	MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1	"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation"
XP_044269119.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044252906.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_044253869.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044259082.1	14	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Ether lipid metabolism"
XP_044267571.1	11	MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Nicotinate and nicotinamide metabolism"
XP_044258035.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_044254429.1	3	MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_044252823.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044269224.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044255750.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_044258393.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_044260518.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044252562.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_044257424.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044258623.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_044264310.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_044269539.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044266214.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044252337.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044265332.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044263587.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044259818.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_044266008.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044253774.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044261334.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044266597.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044272795.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257160.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_044263269.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044263600.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044256268.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_044260657.1	29	Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-5693548;Reactome: R-HSA-6803204;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-349425;Reactome: R-HSA-3371453;Reactome: R-HSA-69541;Reactome: R-HSA-6803207;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;KEGG: 04926+2.7.11.1;Reactome: R-HSA-912446;KEGG: 05170+2.7.11.1	"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Methylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of HSF1-mediated heat shock response";"Stabilization of p53";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human papillomavirus infection";"Thermogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Relaxin signaling pathway";"Meiotic recombination";"Human immunodeficiency virus 1 infection"
XP_044271772.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions";"ECM proteoglycans"
XP_044265650.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044270959.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_044261605.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_044256048.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_044266074.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044262443.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_044260389.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044261602.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044252889.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044267496.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044266877.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044263191.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_044268468.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_044266732.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044262602.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044255933.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044272778.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-2151201	"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis"
XP_044265940.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044257118.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_044254410.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_044266960.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044265187.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_044260574.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044265948.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_044257697.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044263192.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-606279	"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_044272040.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044269155.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044262916.1	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70171	"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis"
XP_044259113.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044272279.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_044266314.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_044266407.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044263714.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-7233	"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_044264392.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Gap junction assembly";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044257560.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044260943.1	9	MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-5663;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664	"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_044255815.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044255817.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044271496.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044261533.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254569.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044252561.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_044254087.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_044263994.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-8953750	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6"
XP_044266971.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_044255943.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044260939.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_044255588.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044271819.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044265869.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044265107.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044258611.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044269921.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044255652.1	33	Reactome: R-HSA-209560;Reactome: R-HSA-937042;Reactome: R-HSA-6811558;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-1257604;Reactome: R-HSA-933542;Reactome: R-HSA-975155;Reactome: R-HSA-975163;Reactome: R-HSA-166058;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-937041;Reactome: R-HSA-193692;Reactome: R-HSA-933541;Reactome: R-HSA-5689896;Reactome: R-HSA-9645460;Reactome: R-HSA-975871;Reactome: R-HSA-450302;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-209543;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-975138;Reactome: R-HSA-168927;Reactome: R-HSA-975110;Reactome: R-HSA-205043;Reactome: R-HSA-450321	"NF-kB is activated and signals survival";"IRAK2 mediated activation of TAK1 complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"PIP3 activates AKT signaling";"TRAF6 mediated NF-kB activation";"MyD88 dependent cascade initiated on endosome";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"IKK complex recruitment mediated by RIP1";"Regulated proteolysis of p75NTR";"TRAF6 mediated IRF7 activation";"Ovarian tumor domain proteases";"Alpha-protein kinase 1 signaling pathway";"MyD88 cascade initiated on plasma membrane";"activated TAK1 mediates p38 MAPK activation";"Protein ubiquitination";"Interleukin-1 signaling";"Ub-specific processing proteases";"p75NTR recruits signalling complexes";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TICAM1, RIP1-mediated IKK complex recruitment";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"NRIF signals cell death from the nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_044253782.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_044266420.1	11	MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7268	"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_044259153.1	10	Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"RSK activation";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human papillomavirus infection";"Thermogenesis"
XP_044270932.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_044268291.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_044264212.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_044257879.1	33	KEGG: 00071+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00982+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7798;MetaCyc: PWY-7396;MetaCyc: PWY-6871;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5480;MetaCyc: PWY-1801;MetaCyc: PWY-6333;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5057;MetaCyc: PWY-5079;MetaCyc: PWY-5486;MetaCyc: PWY-6313;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-6342;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-6802;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5082;KEGG: 00625+1.1.1.1	"Fatty acid degradation";"L-tryptophan degradation V (side chain pathway)";"Tyrosine metabolism";"L-leucine degradation III";"Drug metabolism - cytochrome P450";"Ethanol oxidation";"Protein S-nitrosylation and denitrosylation";"Butanol and isobutanol biosynthesis (engineered)";"3-methylbutanol biosynthesis (engineered)";"Methane metabolism";"Pyruvate fermentation to ethanol I";"Formaldehyde oxidation II (glutathione-dependent)";"Acetaldehyde biosynthesis I";"Metabolism of xenobiotics by cytochrome P450";"L-isoleucine degradation II";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to isobutanol (engineered)";"L-valine degradation II";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol II";"Serotonin degradation";"Naphthalene degradation";"(S)-propane-1,2-diol degradation";"Noradrenaline and adrenaline degradation";"alpha-Linolenic acid metabolism";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis";"Retinol metabolism";"Phenylethanol biosynthesis";"L-methionine degradation III";"Chloroalkane and chloroalkene degradation"
XP_044265953.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044262263.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044257288.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-983695	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_044269911.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044259423.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_044263382.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044266855.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044269506.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044269935.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_044261486.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044268648.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044267063.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044269647.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044268260.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_044269352.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification"
XP_044265993.1	19	Reactome: R-HSA-380320;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7205;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7226	"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Recruitment of mitotic centrosome proteins and complexes";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_044269174.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_044263162.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_044269841.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044265148.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_044257686.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling"
XP_044267577.1	58	MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00903+4.2.1.17;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7778;Reactome: R-HSA-1482798;MetaCyc: PWY-5789;KEGG: 00410+4.2.1.17;KEGG: 00310+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00720+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77350;MetaCyc: PWY-5109;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-6883;MetaCyc: PWY-6583;MetaCyc: PWY-5136;KEGG: 00623+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-1361;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7094;Reactome: R-HSA-77346;MetaCyc: PWY-7654;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-6946;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;Reactome: R-HSA-77285;MetaCyc: PWY-7606;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;Reactome: R-HSA-77305;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945	"Glutaryl-coa degradation";"Fatty acid elongation";"Geraniol degradation";"Phenylalanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Limonene and pinene degradation";"Tryptophan metabolism";"2-methylpropene degradation";"Acyl chain remodeling of CL";"3-hydroxypropanoate/4-hydroxybutanate cycle";"beta-Alanine metabolism";"Lysine degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Carbon fixation pathways in prokaryotes";"Fatty acid degradation";"Butanoate metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fermentation to 2-methylbutanoate";"Fatty acid elongation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Lysine degradation";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation II (plant peroxisome)";"Toluene degradation";"Caprolactam degradation";"Fatty acid degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid salvage";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Geraniol degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Benzoate degradation";"Tryptophan metabolism";"Aminobenzoate degradation";"Benzoate degradation";"Caprolactam degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)"
XP_044265947.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_044271530.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044263602.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_044253578.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044257279.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_044254926.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044264205.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_044259388.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409	"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_044272405.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-428890	"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling"
XP_044272423.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_044261037.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_044254542.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044254175.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_044264800.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044269844.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090	"Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures"
XP_044260103.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_044259619.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044266778.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044257439.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044264223.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_044264288.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044254345.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044259390.1	12	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_044261503.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044265255.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_044260174.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044268306.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_044254225.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044265121.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_044256551.1	8	Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7524	"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)"
XP_044266916.1	3	KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_044271904.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_044260338.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044254264.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway"
XP_044271145.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044262261.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044267166.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044263213.1	12	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417	"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_044262713.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044260968.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_044263885.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044264886.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-383280;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_044266118.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_044256366.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_044266529.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_044271792.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_044272121.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_044272222.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044253910.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044265262.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress"
XP_044269640.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044271580.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_044269907.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_044259880.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044266593.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_044263324.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_044268511.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044254674.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_044264544.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044255759.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044254994.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_044261588.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_044255523.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_044254608.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_044265678.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_044260202.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044265286.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044265805.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)"
XP_044265998.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_044263636.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044266534.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113	"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1"
XP_044261527.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269569.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131	"Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR"
XP_044253457.1	5	Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500;Reactome: R-HSA-75896	"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis"
XP_044271809.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_044266431.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044269688.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044265164.1	13	MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate"
XP_044266336.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_044264305.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_044257901.1	10	Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5676590	"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling"
XP_044261949.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_044264698.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044266449.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044259100.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044253367.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_044264098.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044271193.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044258567.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_044253232.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044265333.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044257780.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_044269913.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044270459.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044266552.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-5578749	"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs"
XP_044260062.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_044253174.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044257338.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044257843.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis"
XP_044252907.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_044270078.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044263498.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044269853.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044269118.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044260281.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_044255382.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_044271722.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044260495.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-114608	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Platelet degranulation"
XP_044264130.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403	"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)"
XP_044262203.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044262878.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044268419.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044266013.1	13	Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896	"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"Aggrephagy";"Josephin domain DUBs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"HSF1 activation";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Protein methylation";"Ovarian tumor domain proteases"
XP_044270065.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_044270789.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044254481.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044271002.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_044263640.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044270187.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044263007.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044254018.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044263193.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_044252330.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044257290.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-5578775	"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Ion homeostasis"
XP_044267146.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044261786.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_044257678.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_044252340.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044258658.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044261223.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044257281.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044266519.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_044271610.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_044257772.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation"
XP_044258613.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_044256689.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638	"p38MAPK events";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway"
XP_044254419.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044256191.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_044271081.1	10	KEGG: 00640+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6535;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-5022;Reactome: R-HSA-916853	"Propanoate metabolism";"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation I";"4-aminobutanoate degradation III";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation V";"Degradation of GABA"
XP_044264986.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_044272524.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044271720.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044260227.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044272626.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044257530.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044264416.1	13	KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)"
XP_044265242.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044267833.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044254547.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044262549.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044269456.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_044265607.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044264055.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044270866.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_044259738.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_044264369.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044272701.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044257044.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)"
XP_044266914.1	5	KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis"
XP_044260396.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_044262794.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_044267006.1	7	MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043	"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_044268247.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044268337.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044260171.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D"
XP_044261895.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_044258597.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_044269190.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_044262204.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044272288.1	58	Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5689901;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-69601	"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Neutrophil degranulation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Metalloprotease DUBs";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_044256211.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism"
XP_044259197.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044266727.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044254103.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044257561.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044271383.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044261423.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044269030.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660	"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (i) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway"
XP_044262224.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_044253388.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044259160.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044263653.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_044266878.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044264251.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_044256781.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044257812.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044263776.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044255263.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044260929.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044264344.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044272604.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044270194.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_044267418.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_044265992.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044267827.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044269073.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044265337.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044256556.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044254411.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_044259050.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044254750.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)"
XP_044266576.1	8	MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_044265610.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044258073.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324	"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_044261241.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-7746;MetaCyc: PWY-6282;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7388;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-8049	"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"ChREBP activates metabolic gene expression";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Pederin biosynthesis"
XP_044259873.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_044261109.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044262029.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_044261121.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
XP_044256785.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044254860.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110314	"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex"
XP_044252608.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044265875.1	26	Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-6804114;Reactome: R-HSA-4615885;Reactome: R-HSA-174417;Reactome: R-HSA-8866654;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-69205;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-1362277;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-69091	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SUMOylation of DNA replication proteins";"Telomere C-strand (Lagging Strand) Synthesis";"E3 ubiquitin ligases ubiquitinate target proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"G1/S-Specific Transcription";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Transcription of E2F targets under negative control by DREAM complex";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Polymerase switching"
XP_044271142.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044262462.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_044263009.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_044270303.1	12	Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1	"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Thermogenesis"
XP_044256693.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_044272098.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044269075.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750	"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"HCMV Early Events";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6"
XP_044263221.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044253414.1	34	Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-427413;Reactome: R-HSA-69202;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167161	"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression";"Cyclin E associated events during G1/S transition";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation"
XP_044269718.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044269132.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044259304.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation"
XP_044255758.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044256196.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040	"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation"
XP_044257140.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044253779.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination"
XP_044272282.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_044266184.1	13	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"Human papillomavirus infection";"Thermogenesis";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044267350.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044262193.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_044256834.1	2	Reactome: R-HSA-420499;Reactome: R-HSA-418594	"Class C/3 (Metabotropic glutamate/pheromone receptors)";"G alpha (i) signalling events"
XP_044255671.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044268111.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_044253962.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_044261634.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_044259032.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_044271527.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044265293.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044261333.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044254134.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044264270.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044261922.1	5	MetaCyc: PWY-6289;KEGG: 00770+2.7.8.7;Reactome: R-HSA-199220;MetaCyc: PWY-6012;MetaCyc: PWY-6012-1	"Petrobactin biosynthesis";"Pantothenate and CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein metabolism";"Acyl carrier protein activation"
XP_044264023.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044253600.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044255647.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
XP_044252502.1	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_044270316.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_044267167.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044270309.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_044268585.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_044268849.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044272158.1	13	Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;Reactome: R-HSA-202433;Reactome: R-HSA-2871809;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-2029485;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039	"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"Generation of second messenger molecules";"FCERI mediated Ca+2 mobilization";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_044263257.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_044254686.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins"
XP_044272537.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_044254284.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_044256037.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044271330.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190861	"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Recycling pathway of L1";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Gap junction assembly"
XP_044257844.1	8	Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1	"Glycolysis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis"
XP_044257672.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_044260104.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_044271798.1	4	KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_044262165.1	6	KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_044266410.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044257656.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044261106.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044260692.1	4	Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_044255204.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044259762.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_044263019.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044260379.1	25	Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467	"Recycling pathway of L1";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Kinesins";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs"
XP_044254681.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_044269158.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044267000.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_044265745.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044253469.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044261596.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_044272426.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-6842	"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II"
XP_044272763.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_044260643.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_044263999.1	4	KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_044256824.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_044262414.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044261421.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_044261893.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_044269498.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044258959.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_044257645.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_044258483.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044255048.1	4	Reactome: R-HSA-446388;Reactome: R-HSA-3000170;Reactome: R-HSA-373753;Reactome: R-HSA-114608	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"Syndecan interactions";"Nephrin family interactions";"Platelet degranulation"
XP_044266671.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_044268285.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_044260577.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044263477.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558	"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_044267062.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044269593.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044267863.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044267380.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044272384.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044258853.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_044256783.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044255024.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044253248.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787	"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'off' state"
XP_044261112.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044266174.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044263132.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_044259729.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_044262856.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044259997.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport"
XP_044272694.1	4	MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50	"Spermidine biosynthesis III";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_044272037.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_044271458.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_044272552.1	8	MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-6556	"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II"
XP_044269135.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis"
XP_044267439.1	18	MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"(R)-cysteate degradation"
XP_044260377.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-3385;MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Synthesis of PC"
XP_044256015.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_044266997.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-0;MetaCyc: PWY-6117	"Arginine and proline metabolism";"Putrescine degradation III";"Spermine and spermidine degradation I"
XP_044265208.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044271020.1	3	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_044257337.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044266385.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044263479.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5467340	"Mitotic Prometaphase";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex"
XP_044268434.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_044252862.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044257023.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269334.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_044258152.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-399719	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors"
XP_044269169.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044263574.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044269082.1	4	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142;Reactome: R-HSA-4549349;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_044256465.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044255153.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044264713.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_044269655.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044266474.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044260897.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044254525.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044268283.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_044256823.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_044271762.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044267371.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044264363.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044269920.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044254715.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_044268167.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044265260.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_044270856.1	5	MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-7279	"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)"
XP_044261531.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044261696.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044260979.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044254358.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044257336.1	19	Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026	"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Chylomicron assembly";"VLDL assembly";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Chylomicron clearance"
XP_044270145.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling"
XP_044257834.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044255492.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044260508.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044255049.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_044267283.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_044255586.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044262364.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044269799.1	7	MetaCyc: PWY-6724;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Starch degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_044263913.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044259230.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_044256094.1	7	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044267012.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044271612.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_044254342.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_044268359.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_044262046.1	4	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism"
XP_044259990.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_044269514.1	17	Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_044257974.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_044253730.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044267443.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_044265011.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044261658.1	7	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism"
XP_044272193.1	6	Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731	"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_044270170.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044271582.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044262844.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044264921.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044256557.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044262609.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_044269113.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044255623.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044269460.1	11	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)"
XP_044252648.1	3	Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_044266089.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044258474.1	6	MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_044263137.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044254739.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044253432.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_044269452.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044272202.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044264316.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_044270939.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044253465.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_044269459.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_044262581.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044272430.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_044257999.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044256149.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-3214858	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines"
XP_044265671.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044255385.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_044265661.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_044260957.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_044253276.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044258047.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-111932	"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF activation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB"
XP_044268188.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044267187.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044258332.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism"
XP_044270858.1	13	Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061	"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I"
XP_044265252.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044265311.1	10	MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_044267674.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044270845.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_044272359.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing"
XP_044263905.1	34	Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-9639288;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859	"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"Amino acids regulate mTORC1";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly"
XP_044260864.1	17	MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5744;Reactome: R-HSA-2426168	"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Fatty acid biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)"
XP_044263519.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044271487.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795	"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling"
XP_044270642.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044272465.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044258972.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044261497.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_044256950.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044266209.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_044267287.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044257425.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_044255995.1	5	Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579	"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_044270202.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256099.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044267623.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044270992.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044256553.1	8	KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I"
XP_044265285.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044265668.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_044269237.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974	"Neddylation";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"G2/M Checkpoints";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway"
XP_044264521.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044253587.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_044258740.1	6	MetaCyc: PWY-6907;MetaCyc: PWY-6898;Reactome: R-HSA-196819;MetaCyc: PWY-7356;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism"
XP_044272733.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_044257080.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044269395.1	7	MetaCyc: PWY-8004;MetaCyc: PWY-6855;Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_044257725.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044265401.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044257299.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044253935.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_044253150.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044253062.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044258731.1	9	KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549	"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Arginine biosynthesis";"L-glutamine biosynthesis III"
XP_044265161.1	13	KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3	"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Folate polyglutamylation";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes"
XP_044259827.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_044267816.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044266411.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044254286.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044268304.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044269303.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044254631.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854	"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly"
XP_044272253.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044261012.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_044270266.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555	"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events"
XP_044264346.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044258646.1	7	Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346	"Ligand-receptor interactions";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Hedgehog ligand biogenesis"
XP_044266690.1	6	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_044271302.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_044252468.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_044271495.1	11	Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631	"RAF/MAP kinase cascade";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility"
XP_044263190.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_044262162.1	6	MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_044262169.1	6	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism"
XP_044259109.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044253408.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044256939.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044262408.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_044271459.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_044265248.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_044257157.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_044265210.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_044255749.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_044261909.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044268239.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044272056.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044269874.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_044262950.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044255592.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044257282.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044259337.1	5	MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_044253423.1	5	KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;MetaCyc: PWY-5269;MetaCyc: PWY-5668	"Glycerophospholipid metabolism";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I"
XP_044262962.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_044272171.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044263282.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_044254825.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_044261185.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_044255377.1	26	Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973	"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_044256679.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_044258918.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044272769.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_044254961.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-881907;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors"
XP_044253960.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044272302.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_044258303.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_044253425.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044259271.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044266943.1	12	Reactome: R-HSA-71032;KEGG: 00630+6.4.1.3;KEGG: 00720+6.4.1.3;Reactome: R-HSA-196780;KEGG: 00280+6.4.1.3;MetaCyc: PWYG-321;Reactome: R-HSA-3371599;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.3	"Propionyl-CoA catabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Valine, leucine and isoleucine degradation";"";"Defective HLCS causes multiple carboxylase deficiency";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism"
XP_044266553.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044255619.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_044268033.1	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_044259195.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044253352.1	12	KEGG: 00660+4.1.3.25;MetaCyc: PWY-6728;MetaCyc: PWY-7295;MetaCyc: PWY-7118;MetaCyc: PWY-7294;MetaCyc: PWY-7854;MetaCyc: PWY-5749;MetaCyc: PWY-6969;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;KEGG: 00620+2.3.3.9;MetaCyc: PWY-5744	"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"L-arabinose degradation IV";"Chitin degradation to ethanol";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Itaconate degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate assimilation"
XP_044257699.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041	"VLDL clearance";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Chylomicron assembly";"Retinoid metabolism and transport";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling"
XP_044252993.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_044264960.1	11	Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_044267129.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044257437.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044260691.1	4	MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_044252568.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044261918.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044264797.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044261424.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044256955.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_044272196.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044268809.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044266419.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044253386.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044260029.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044269257.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_044265127.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044270140.1	4	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_044272007.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_044266315.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044260302.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_044272106.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_044253359.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_044255719.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044253294.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652	"Dual incision in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_044269713.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_044267949.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044265804.1	13	KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916	"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation"
XP_044271942.1	44	Reactome: R-HSA-3371453;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;Reactome: R-HSA-445144;Reactome: R-HSA-74749;Reactome: R-HSA-5674135;Reactome: R-HSA-2029482;Reactome: R-HSA-112409;Reactome: R-HSA-982772;Reactome: R-HSA-2871796;Reactome: R-HSA-9635465;Reactome: R-HSA-444257;Reactome: R-HSA-5668599;Reactome: R-HSA-6811558;Reactome: R-HSA-5654727;Reactome: R-HSA-375165;Reactome: R-HSA-198753;Reactome: R-HSA-456926;Reactome: R-HSA-879415;Reactome: R-HSA-2559580;Reactome: R-HSA-6802948;Reactome: R-HSA-5674499;Reactome: R-HSA-2559582;Reactome: R-HSA-6802946;Reactome: R-HSA-5663213;Reactome: R-HSA-5654733;Reactome: R-HSA-450341;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.24;Reactome: R-HSA-8940973;Reactome: R-HSA-1295596;Reactome: R-HSA-881907;Reactome: R-HSA-5673001;Reactome: R-HSA-9627069;Reactome: R-HSA-9634638;Reactome: R-HSA-5654726;Reactome: R-HSA-8943724;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-6802952;Reactome: R-HSA-202670;Reactome: R-HSA-162658;Reactome: R-HSA-170968	"Regulation of HSF1-mediated heat shock response";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Signal transduction by L1";"Signal attenuation";"MAP2K and MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"RAF-independent MAPK1/3 activation";"Growth hormone receptor signaling";"FCERI mediated MAPK activation";"Suppression of apoptosis";"RSK activation";"RHO GTPases Activate NADPH Oxidases";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR2 signaling";"NCAM signaling for neurite out-growth";"ERK/MAPK targets";"Thrombin signalling through proteinase activated receptors (PARs)";"Advanced glycosylation endproduct receptor signaling";"Oxidative Stress Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling by moderate kinase activity BRAF mutants";"RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR4 signaling";"Activation of the AP-1 family of transcription factors";"Signaling downstream of RAS mutants";"mTOR signaling pathway";"RUNX2 regulates osteoblast differentiation";"Spry regulation of FGF signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"RAF/MAP kinase cascade";"Regulation of the apoptosome activity";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR1 signaling";"Regulation of PTEN gene transcription";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"Signaling by BRAF and RAF fusions";"ERKs are inactivated";"Golgi Cisternae Pericentriolar Stack Reorganization";"Frs2-mediated activation"
XP_044270578.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_044272084.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044265159.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_044256782.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_044257407.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation"
XP_044264802.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044271774.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_044259713.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044270728.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)"
XP_044255452.1	13	Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-6370;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061	"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I"
XP_044262379.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination"
XP_044260924.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044262003.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044272523.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044270862.1	13	MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061	"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I"
XP_044263289.1	3	MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099	"L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling"
XP_044266925.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044269556.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044256447.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_044260094.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044260870.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination"
XP_044257955.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_044256266.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044270340.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_044260205.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044255498.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044264780.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044266351.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_044266060.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044271899.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_044264426.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044255754.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_044270912.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044268525.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_044262752.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_044270998.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044270431.1	31	MetaCyc: PWY-5989;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-7664;MetaCyc: PWY-5142;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-8047;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-7388	"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)"
XP_044258144.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719	"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Ion homeostasis";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors"
XP_044257900.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764	"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling"
XP_044266505.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044253856.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044253959.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044261790.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_044264906.1	21	MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_044265067.1	10	MetaCyc: PWY-7328;MetaCyc: PWY-7344;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Galactose catabolism"
XP_044268038.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_044258877.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044270246.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"Cis-zeatin biosynthesis"
XP_044267798.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_044269397.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044263584.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_044256315.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044263265.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_044255616.1	12	MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278	"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Transport and synthesis of PAPS";"Sulfur metabolism";"Purine metabolism";"Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III"
XP_044270464.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044261701.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_044268006.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_044253675.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_044270763.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_044258193.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837	"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases"
XP_044263207.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_044263722.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044263158.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_044257722.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044261428.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_044261183.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_044272438.1	9	MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70263	"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis"
XP_044272716.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044262463.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919	"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils"
XP_044255230.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_044266478.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044260026.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-6798695	"Synthesis of PC";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Neutrophil degranulation"
XP_044256892.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044257335.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044253243.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044254645.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044256338.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_044271586.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044252457.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044260296.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044261986.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87	"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis"
XP_044254216.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_044253125.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_044256881.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_044257400.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044254643.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044268926.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044270096.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044269112.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044265047.1	12	KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9	"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_044264504.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044267888.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-2467813	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids"
XP_044258133.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324	"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_044265899.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_044254270.1	9	Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_044256816.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_044258004.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7385;MetaCyc: PWY-7902	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis"
XP_044265125.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_044269829.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_044257716.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044271635.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_044253173.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044254361.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044267954.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_044272647.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044253725.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044257298.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044272697.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044257024.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269482.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044270469.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044262630.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_044259061.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_044265043.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044271196.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044264931.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_044253281.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044257091.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_044264290.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044257214.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_044266322.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_044260728.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044252768.1	6	KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis"
XP_044252571.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044253000.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_044269622.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis"
XP_044267926.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Translation initiation complex formation"
XP_044265502.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_044267204.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_044262136.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_044268418.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_044268411.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_044271350.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_044257911.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_044270989.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044266982.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044263232.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_044266560.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_044265752.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238	"Tat-mediated elongation of the HIV-1 transcript";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation"
XP_044270226.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044261690.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044265410.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044269685.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044272808.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_044267244.1	5	MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_044254949.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044254776.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044270243.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"Zeatin biosynthesis"
XP_044259694.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_044263943.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044272286.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport"
XP_044255421.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_044260145.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044263865.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_044272385.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044253503.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8936459	"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_044262413.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044269620.1	16	Reactome: R-HSA-166058;Reactome: R-HSA-5602498;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-975871;Reactome: R-HSA-9020702;Reactome: R-HSA-1257604;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-975138;Reactome: R-HSA-5603041;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-5602680;Reactome: R-HSA-1236974	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"MyD88 cascade initiated on plasma membrane";"Interleukin-1 signaling";"PIP3 activates AKT signaling";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR5)";"ER-Phagosome pathway"
XP_044272734.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_044255706.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167160	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_044261793.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_044259938.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044267503.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044263173.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044270039.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_044263156.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_044260423.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_044268195.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256008.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044266333.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_044256219.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_044264329.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044258172.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044261036.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044267456.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044264871.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8939236;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production"
XP_044260719.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_044264617.1	4	KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine"
XP_044259655.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044252551.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044253013.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_044254187.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_044253961.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044271832.1	14	MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6901	"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation"
XP_044259995.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport"
XP_044268282.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_044267150.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_044260525.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044264895.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_044256132.1	12	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_044261427.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044269412.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044266987.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_044268540.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_044270564.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044272406.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_044262143.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044256896.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044270323.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044256209.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_044252874.1	12	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism"
XP_044253381.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_044267235.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_044269208.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_044252789.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_044263235.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_044262213.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044267464.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_044271387.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044262393.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"PPARA activates gene expression";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_044265195.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044256345.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins"
XP_044265114.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044270988.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044257670.1	13	KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-5132	"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Ethanol oxidation";"Propanoate metabolism";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis"
XP_044261995.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_044271254.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044269411.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044261569.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_044272192.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001	"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade"
XP_044259499.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044262866.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044262921.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_044260869.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks"
XP_044252868.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_044267783.1	16	Reactome: R-HSA-1251985;Reactome: R-HSA-9664565;Reactome: R-HSA-1963640;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-1250342;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795	"Nuclear signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"GRB2 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB4 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling"
XP_044261903.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044269378.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_044260491.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695	"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation"
XP_044254490.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044258292.1	4	KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I";"Formation of xylulose-5-phosphate"
XP_044263541.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044268122.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163359	"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation"
XP_044259104.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044267074.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044259033.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_044262404.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044265785.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_044261508.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044262727.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_044255012.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044262243.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_044254881.1	10	MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1	"Glycerol degradation to butanol";"Glycolysis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Inositol phosphate metabolism"
XP_044254198.1	10	MetaCyc: PWY-7198;MetaCyc: PWY-3841;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7199;MetaCyc: PWY-7187;Reactome: R-HSA-69205	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Folate transformations II (plants)";"Pyrimidine metabolism";"One carbon pool by folate";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription"
XP_044262913.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044269090.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_044262407.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044254341.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_044272268.1	6	MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_044267647.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_044261273.1	14	Reactome: R-HSA-205043;Reactome: R-HSA-6798695;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2122948	"NRIF signals cell death from the nucleus";"Neutrophil degranulation";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_044266863.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_044260832.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_044252822.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12	"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism"
XP_044263863.1	5	KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_044262302.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044254986.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_044265093.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_044260162.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_044264213.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_044271052.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044261689.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_044253781.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_044256970.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044257384.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044271061.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044270849.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_044269852.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044270786.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_044262248.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_044255392.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259572.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_044255658.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_044269222.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044258935.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_044254181.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
XP_044257597.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication"
XP_044270232.1	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_044254962.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044261902.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044258729.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044257781.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_044267924.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044262421.1	7	MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702	"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I"
XP_044265707.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_044257314.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_044263992.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_044264334.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044264425.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044267707.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_044257689.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_044265039.1	13	MetaCyc: PWY-7410;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-7709;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-5123	"Ipsdienol biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_044260118.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044253652.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_044259570.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_044267640.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_044269497.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044264609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044261852.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_044269592.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044253745.1	40	MetaCyc: PWY-5177;KEGG: 00903+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5789;MetaCyc: PWY-7778;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6883;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7779;MetaCyc: PWY-7654;MetaCyc: PWY-7094;MetaCyc: PWY-7007;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5138;MetaCyc: PWY-6944;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7656;MetaCyc: PWY-7606;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945	"Glutaryl-coa degradation";"Limonene and pinene degradation";"Phenylalanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"2-methylpropene degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Fatty acid elongation";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Toluene degradation";"Pyruvate fermentation to butanol I";"Methyl tert-butyl ether degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid salvage";"Methyl ketone biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Androstenedione degradation";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Benzoate degradation";"Tryptophan metabolism";"Caprolactam degradation";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)"
XP_044263619.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231	"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production"
XP_044260361.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044258800.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044270581.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_044269862.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_044255451.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_044262351.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_044254265.1	9	Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_044266045.1	4	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis"
XP_044262755.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_044253662.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112	"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification"
XP_044265595.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-432722	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis"
XP_044270203.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044253387.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_044257658.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044270508.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_044271435.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044253258.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044263165.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_044267977.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_044254594.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_044257466.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044254951.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_044261326.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044261699.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_044254704.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044256581.1	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268	"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_044261290.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044265537.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044254108.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_044266213.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_044272074.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-1655829	"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_044262172.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_044265323.1	12	Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression"
XP_044260498.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946	"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants"
XP_044257627.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044262759.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_044265616.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_044258063.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932	"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB"
XP_044267681.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_044254696.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_044256317.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044268189.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044264438.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_044269231.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044268254.1	14	KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-3781;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-6969	"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_044267685.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_044260694.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-6453	"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis"
XP_044259983.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_044269680.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044264169.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044266427.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044264924.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044264522.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044259955.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044269001.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_044258181.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044263006.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_044256629.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_044258319.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_044266166.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044265706.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_044256817.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_044268303.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044267665.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044260358.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044263631.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044264793.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044260571.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_044254317.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044272770.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_044259501.1	2	Reactome: R-HSA-3785653;Reactome: R-HSA-3322077	"Myoclonic epilepsy of Lafora";"Glycogen synthesis"
XP_044257939.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505	"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_044257089.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044259196.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044256391.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044265769.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044272364.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_044258258.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_044265244.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044266189.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044264283.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism"
XP_044269089.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_044265287.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_044264792.1	3	Reactome: R-HSA-901032;Reactome: R-HSA-532668;MetaCyc: PWY-7511	"ER Quality Control Compartment (ERQC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein ubiquitination"
XP_044263354.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044262497.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044260175.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044252782.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044271681.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044255055.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_044267228.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044268476.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_044271623.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044272501.1	25	Reactome: R-HSA-163359;Reactome: R-HSA-381771;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-392170	"Glucagon signaling in metabolic regulation";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12"
XP_044260894.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044265903.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044262348.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_044272221.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044268387.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9619483	"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs"
XP_044268556.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044259106.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044252406.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044258187.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_044260105.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_044266043.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_044271191.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044260797.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044262271.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044268561.1	15	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence"
XP_044268062.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_044253170.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_044253721.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044262965.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Neutrophil degranulation";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044252425.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1"
XP_044257882.1	15	Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity"
XP_044262924.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_044258020.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044261981.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044266405.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_044261564.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_044269682.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044256907.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044263628.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044268316.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044256825.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_044253814.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044258781.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_044257572.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_044257303.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044266573.1	8	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7117	"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_044253623.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-432720	"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Negative regulation of MET activity";"EGFR downregulation";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
XP_044255560.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044271384.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044263627.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044254882.1	10	KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-5484	"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Inositol phosphate metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)"
XP_044254540.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044264340.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044262234.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044258051.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044259383.1	8	MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481	"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate"
XP_044264258.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_044258042.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_044263495.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044264143.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_044258618.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_044268416.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044265269.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256756.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_044252453.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044271577.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044266388.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-167160	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_044257312.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_044265326.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044260534.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269706.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044260283.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_044265162.1	13	KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3	"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Folate polyglutamylation";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes"
XP_044263399.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_044269032.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1	"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism"
XP_044261703.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044263966.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_044271060.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044253614.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044270100.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_044263287.1	52	Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-73863;Reactome: R-HSA-77075	"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_044267301.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_044258675.1	14	MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_044255657.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589	"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_044269417.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044272771.1	8	MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_044267639.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_044263756.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044262378.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_044270429.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_044257219.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_044271896.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044263767.1	4	KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047	"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol"
XP_044257563.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044270322.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044254274.1	19	Reactome: R-HSA-8876725;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Protein methylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_044267415.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044268366.1	5	Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4	"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism"
XP_044272546.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044255582.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044268871.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044268549.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044257283.1	13	Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-381676	"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_044257669.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044271526.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044264727.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044272383.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044262095.1	17	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044263678.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253	"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex"
XP_044265928.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044255488.1	3	Reactome: R-HSA-8939211;Reactome: R-HSA-9022699;Reactome: R-HSA-3371497	"ESR-mediated signaling";"MECP2 regulates neuronal receptors and channels";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_044269502.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_044252288.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044272112.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_044253143.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40	"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
XP_044265117.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044269100.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling"
XP_044256829.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_044259398.1	8	KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268	"Cysteine and methionine metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism"
XP_044272045.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044257124.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_044255774.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_044256110.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_044268583.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_044252855.1	17	MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1	"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Guanine and guanosine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II"
XP_044258547.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044259461.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044271083.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044259793.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_044270776.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"MASTL Facilitates Mitotic Progression";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_044268997.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"Collagen degradation";"MHC class II antigen presentation"
XP_044267165.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044253007.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_044271194.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_044262442.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends"
XP_044264607.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044255069.1	18	Reactome: R-HSA-8866911;Reactome: R-HSA-69231;Reactome: R-HSA-8878166;Reactome: R-HSA-9616222;Reactome: R-HSA-198323;Reactome: R-HSA-8852276;Reactome: R-HSA-69656;Reactome: R-HSA-69563;Reactome: R-HSA-2559586;Reactome: R-HSA-69202;Reactome: R-HSA-187577;Reactome: R-HSA-9617828;Reactome: R-HSA-5674400;Reactome: R-HSA-2559582;Reactome: R-HSA-8941855;Reactome: R-HSA-69895;Reactome: R-HSA-6804116;Reactome: R-HSA-6785807	"TFAP2 (AP-2) family regulates transcription of cell cycle factors";"Cyclin D associated events in G1";"Transcriptional regulation by RUNX2";"Transcriptional regulation of granulopoiesis";"AKT phosphorylates targets in the cytosol";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cyclin A:Cdk2-associated events at S phase entry";"p53-Dependent G1 DNA Damage Response";"DNA Damage/Telomere Stress Induced Senescence";"Cyclin E associated events during G1/S transition";"SCF(Skp2)-mediated degradation of p27/p21";"FOXO-mediated transcription of cell cycle genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX3 regulates CDKN1A transcription";"Transcriptional activation of cell cycle inhibitor p21";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"Interleukin-4 and Interleukin-13 signaling"
XP_044263843.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044266324.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044265182.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044262227.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044252732.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044260347.1	40	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes"
XP_044261924.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044253732.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_044260581.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044255371.1	26	Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575	"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"HATs acetylate histones";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling"
XP_044257899.1	10	Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation"
XP_044255309.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044267445.1	6	KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165	"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_044256878.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044268390.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-9619483	"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs"
XP_044254754.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition"
XP_044271848.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_044265188.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044252552.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_044258537.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044259060.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_044253854.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044259286.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044255491.1	6	Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_044267797.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_044256472.1	6	KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
XP_044259379.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044266122.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044272695.1	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III"
XP_044253805.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_044262293.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044261006.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044258381.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis"
XP_044271557.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044254842.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_044258816.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044264678.1	9	Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-5649702;Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9656255	"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Localization";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding"
XP_044253223.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044261240.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044266990.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5689880	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Ub-specific processing proteases"
XP_044256788.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044271470.1	11	KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7124;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-6549;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42	"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_044257486.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044258326.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis"
XP_044269300.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_044260300.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044261257.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)"
XP_044261034.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044264894.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_044253747.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044252339.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044264152.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044256023.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1	"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism"
XP_044271726.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_044265951.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044262914.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044267349.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044254654.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044262337.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_044255932.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044267199.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044257935.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_044267416.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044257724.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044258135.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_044268892.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_044253893.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_044269216.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_044269308.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044259171.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044252926.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044271007.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044252796.1	10	MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-5030	"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III"
XP_044264508.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_044262440.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"G2/M DNA damage checkpoint"
XP_044268864.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044270432.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044252677.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_044254349.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044261182.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_044268459.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_044272603.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044261458.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_044269375.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_044263741.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044270983.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044267838.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_044253618.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044255383.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_044262050.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_044270774.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-1368082	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression"
XP_044260201.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044268492.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044256238.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044272488.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044263979.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044254595.1	6	KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;Reactome: R-HSA-1660499;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_044269930.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_044262157.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_044268451.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044264349.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_044272350.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044271523.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044257021.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044261455.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_044272227.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_044264102.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044266827.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044267999.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044253822.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044257341.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044254283.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900	"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_044253490.1	7	MetaCyc: PWY-6123;MetaCyc: PWY-7219;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III"
XP_044271297.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044268565.1	11	Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-5913	"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)"
XP_044266387.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044253852.1	18	MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561	"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methylaspartate cycle";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_044261598.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_044269797.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044257383.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044253012.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_044269455.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044254606.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044263968.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044262189.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044266959.1	12	Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-73762;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_044261623.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_044267516.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044259627.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_044268548.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044258459.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_044265131.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_044269936.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044272097.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_044262217.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541	"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway"
XP_044266071.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044259316.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044258237.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044272382.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044256114.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_044271293.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044265546.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_044260512.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044254412.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_044262392.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976	"Xenobiotics";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols"
XP_044261089.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_044257152.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_044255497.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044265886.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_044252917.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044254755.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205	"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription"
XP_044256473.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_044264465.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-9013973	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7"
XP_044266191.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044254866.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044255456.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044255490.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_044269900.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_044261247.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_044252604.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_044256240.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044258000.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044265023.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044261521.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044256144.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-3214858;Reactome: R-HSA-400253	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"RMTs methylate histone arginines";"Circadian Clock"
XP_044253326.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_044265766.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044272341.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044259535.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_044254878.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044259372.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044264991.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_044265259.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_044266176.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_044267440.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044269396.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044257632.1	5	Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism"
XP_044260515.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044254268.1	9	KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_044256838.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044258142.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_044258320.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_044257861.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044263920.1	3	KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
XP_044260023.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044261269.1	4	KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_044269117.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044268695.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_044272290.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_044266915.1	5	KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_044267037.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044270189.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_044263249.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044268682.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_044257154.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_044263288.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044252309.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044265768.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044256612.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_044257225.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_044260405.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044267409.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
XP_044253288.1	9	KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)"
XP_044254745.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044264101.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044269344.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_044259448.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability"
XP_044270987.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044260760.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_044252919.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044270444.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044256076.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_044268108.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_044256550.1	8	MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781	"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression"
XP_044265690.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044257541.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044257902.1	10	Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607764	"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling"
XP_044262422.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044253165.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044266686.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_044259636.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-381426	"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_044261855.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044261976.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044264920.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044264188.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044266644.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044269598.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044256655.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_044269402.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044257370.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044254685.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins"
XP_044257854.1	6	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_044262765.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044259748.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044258253.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_044263480.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-141444	"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"RAF activation";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044257698.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_044257022.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044265703.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_044264414.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_044261143.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772	"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling"
XP_044265776.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_044266975.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_044266272.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044268481.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_044262447.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044256906.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044270446.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044256392.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044265192.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_044257934.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_044253374.1	7	Reactome: R-HSA-5362517;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_044252331.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044262110.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044269610.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044253948.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044256485.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_044265398.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_044259397.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044254230.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044257806.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044265136.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_044255245.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044261657.1	7	KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_044268653.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_044265417.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044264056.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044260664.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044268420.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044264176.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_044267915.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044270167.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_044259425.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_044254945.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044261522.1	19	KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-6969	"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_044254730.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044269354.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_044263434.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044263385.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044262168.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism"
XP_044261789.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_044259375.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044263364.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044271481.1	11	Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling"
XP_044263302.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044252920.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044262232.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_044253247.1	20	Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-166208;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165159	"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"mTORC1-mediated signalling";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Human papillomavirus infection";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"mTOR signalling"
XP_044258143.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044267519.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044265408.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_044256847.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044272367.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044270775.1	9	Reactome: R-HSA-191859;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206	"snRNP Assembly";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha"
XP_044260457.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044255267.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044271349.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_044270270.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-381426	"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_044262550.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044265737.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_044260736.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044266317.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044256207.1	18	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044252998.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_044268775.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_044258541.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_044265657.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044255648.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_044260579.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044268588.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_044263855.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_044255216.1	5	Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
XP_044269463.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044255715.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-5626467	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs"
XP_044263476.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467340	"Mitotic Prometaphase";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex"
XP_044263140.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044271388.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044263939.1	7	MetaCyc: PWY-7805;MetaCyc: PWY-6605;Reactome: R-HSA-6798695;MetaCyc: PWY-6610;MetaCyc: PWY-7807;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7	"(aminomethyl)phosphonate degradation";"Adenine and adenosine salvage II";"Neutrophil degranulation";"Adenine salvage";"Glyphosate degradation III";"Purine salvage";"Purine metabolism"
XP_044272260.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044259579.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044261994.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_044270924.1	6	Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_044256934.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_044269116.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044266044.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
XP_044267061.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044253690.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_044270843.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_044266538.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044258068.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044255152.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_044255155.1	10	MetaCyc: PWY-6365;MetaCyc: PWY-6366;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-983231;KEGG: 04070+2.7.1.159	"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Factors involved in megakaryocyte development and platelet production";"Phosphatidylinositol signaling system"
XP_044271712.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_044272046.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044262042.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_044253424.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_044271247.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044263433.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044253484.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044266876.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044268425.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044254369.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044260499.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_044269246.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044258313.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_044252520.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044255963.1	8	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6"
XP_044263532.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044257654.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044260874.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis"
XP_044261405.1	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_044262020.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044267132.1	5	Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-6798695	"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation"
XP_044265950.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044265405.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044254248.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_044259963.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism"
XP_044259517.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_044264201.1	5	Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841	"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)"
XP_044254393.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044258252.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_044267855.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044259367.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_044260560.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257810.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044263319.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-400253	"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock"
XP_044256683.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_044269120.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044272404.1	6	Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_044257877.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_044263223.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044270867.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_044256205.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190861	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Recycling pathway of L1";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Gap junction assembly"
XP_044260734.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044268312.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044263359.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044267340.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044272704.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044255779.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044257837.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044271422.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044265229.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044262430.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044260123.1	19	Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484	"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"VLDL assembly";"Retinoid metabolism and transport";"Chylomicron assembly";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"LDL clearance";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Chylomicron clearance";"Scavenging by Class F Receptors"
XP_044258640.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044252527.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_044256543.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427	"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins"
XP_044261633.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_044271084.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_044258850.1	8	Reactome: R-HSA-8950505;Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-6791462;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-6791055	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P"
XP_044252386.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044258741.1	6	Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6907;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2	"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine metabolism"
XP_044263345.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044268435.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_044259936.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044258148.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_044252885.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044267776.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_044257399.1	5	MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_044272427.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism"
XP_044253553.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_044272502.1	25	Reactome: R-HSA-163359;Reactome: R-HSA-381771;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-392170	"Glucagon signaling in metabolic regulation";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12"
XP_044262303.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_044270519.1	9	Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_044263993.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6"
XP_044271230.1	14	MetaCyc: PWY-3781;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-7279	"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)"
XP_044257538.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044269206.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism"
XP_044267382.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_044263262.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_044265994.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044258244.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_044265700.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044259042.1	9	KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.141;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6385;MetaCyc: PWY-5265;MetaCyc: PWY-6471;MetaCyc: PWY-6470;Reactome: R-HSA-5633231	"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_044265402.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044257693.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_044256199.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_044258484.1	14	MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044258372.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_044258991.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_044271168.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044258209.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736	"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors"
XP_044257539.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044253497.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044258920.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_044262518.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044261523.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_044254749.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781	"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression"
XP_044258901.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044263777.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044252289.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044263881.1	10	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_044259803.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_044267160.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_044269236.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044253517.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_044253486.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044272723.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044263141.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_044265753.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_044266309.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_044263365.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044271689.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_044269372.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_044255461.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044270269.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling"
XP_044260492.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135	"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation"
XP_044260681.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044266514.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044272629.1	6	Reactome: R-HSA-983168;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity"
XP_044263793.1	4	MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558	"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine"
XP_044260395.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044254272.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044267955.1	14	Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397	"Translesion synthesis by POLI";"Polymerase switching";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_044264166.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044252905.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_044255376.1	26	Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606	"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Circadian Clock";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044261975.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044262246.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044260542.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044262096.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_044266150.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044265440.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_044269707.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939	"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)"
XP_044257676.1	5	MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis"
XP_044261982.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044259411.1	7	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-212300	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"HCMV Early Events";"PRC2 methylates histones and DNA"
XP_044260255.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044269420.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044265794.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_044260308.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044263473.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_044260095.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_044265715.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8852276;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044267607.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044262355.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044265115.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044271708.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_044267212.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044259671.1	6	MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;MetaCyc: PWY-7765	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_044270166.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_044261443.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
XP_044254066.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044263632.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044269376.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_044253975.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044255944.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044262851.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632	"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis"
XP_044263769.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_044268582.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_044252854.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events"
XP_044263950.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_044260124.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_044265298.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_044271721.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044256873.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_044253506.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation"
XP_044254987.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044256457.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044254671.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_044270392.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044272305.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_044265828.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_044263161.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_044258953.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-72163	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mRNA Splicing - Major Pathway"
XP_044257150.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_044254385.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_044263874.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044272300.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044260748.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_044272514.1	14	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
XP_044256330.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes"
XP_044258329.1	7	MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_044259087.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044258726.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_044260310.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044267676.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044264600.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044257065.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-432142	"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"Retinoid metabolism and transport";"Chylomicron assembly";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"LDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"VLDL clearance";"Platelet sensitization by LDL"
XP_044257446.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044259649.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044259198.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044256768.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044259170.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_044259956.1	7	MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism"
XP_044257277.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_044263817.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044262006.1	9	Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044263982.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044261538.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044266729.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_044257863.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044253838.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_044268257.1	4	Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14	"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism"
XP_044262863.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044269686.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044257017.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_044261537.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044258968.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_044262036.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_044265124.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044260580.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044264572.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167200	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_044264122.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044258374.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_044254565.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_044255364.1	8	Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Photosynthesis";"Ion channel transport";"Amino acids regulate mTORC1"
XP_044254085.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044260987.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044267345.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044267262.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_044268240.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044272356.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198	"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis"
XP_044262294.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_044268008.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_044264245.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044255528.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044270863.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_044256645.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053	"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II"
XP_044267578.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044261122.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044262423.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044253264.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_044260324.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044260536.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044259947.1	10	MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7791;Reactome: R-HSA-500753;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686;KEGG: 00240+6.3.5.5	"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_044260863.1	17	MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2	"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Fatty acid biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"Aflatoxin biosynthesis"
XP_044266319.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_044253686.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_044267338.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044268032.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118;MetaCyc: PWY-4261	"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerol degradation I"
XP_044272792.1	15	Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167243	"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery"
XP_044265193.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_044258544.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_044254396.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044270596.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_044271644.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_044271646.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_044269842.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044260878.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_044258322.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_044263234.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_044254566.1	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_044272458.1	10	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_044272451.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256092.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044269779.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044257592.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044267830.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044269339.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044269027.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660	"PKA activation";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway"
XP_044269238.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_044266797.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044267254.1	12	MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409	"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_044255621.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_044268874.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_044259573.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_044267622.1	29	Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801	"Dual Incision in GG-NER";"HSF1 activation";"Translesion synthesis by POLI";"Meiotic recombination";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair"
XP_044268500.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs"
XP_044255614.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044272793.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044261417.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044263757.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044253676.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_044270489.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044261655.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044252831.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044260289.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_044256151.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044263255.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044268979.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257566.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_044264904.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044272271.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_044253221.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044264341.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044271784.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_044263263.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_044259609.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_044263768.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_044255823.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-983168	"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Neddylation";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044263797.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation"
XP_044270947.1	9	Reactome: R-HSA-2173789;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535	"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer"
XP_044272710.1	10	MetaCyc: PWY-6807;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Other glycan degradation";"Sphingolipid metabolism"
XP_044262662.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044270575.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044252983.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_044267453.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044267996.1	12	MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-6708	"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_044259424.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044266091.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044265045.1	12	KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-7238	"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Sucrose biosynthesis II"
XP_044265133.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-196299	"Mitotic Prometaphase";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade"
XP_044257904.1	11	MetaCyc: PWY-6453;MetaCyc: PWY-8055;Reactome: R-HSA-2029485;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4	"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism"
XP_044255655.1	14	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_044257373.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044258255.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044258251.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_044264890.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_044260063.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_044269798.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044266556.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_044257991.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044258037.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_044268880.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68952	"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation"
XP_044258929.1	11	Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2173796;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Notch-HLH transcription pathway"
XP_044264618.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_044255009.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044269490.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection"
XP_044254387.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044261128.1	10	Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Ub-specific processing proteases";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"HATs acetylate histones";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_044265841.1	8	MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-4983;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"Urea cycle";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"Urea cycle"
XP_044268361.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_044270514.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044263580.1	10	MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;Reactome: R-HSA-1989781	"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"PPARA activates gene expression"
XP_044264052.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination"
XP_044260139.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044269690.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044269860.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044269831.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3	"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism"
XP_044266999.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_044263160.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_044267159.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_044257347.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044262753.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria"
XP_044265733.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044261349.1	6	KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
XP_044261234.1	6	Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-6174	"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)"
XP_044261100.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044258462.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_044260367.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_044256208.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_044253228.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044263645.1	8	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;MetaCyc: PWY-5269;Reactome: R-HSA-1483148	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Synthesis of PG"
XP_044269262.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_044270963.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044256467.1	6	MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077;MetaCyc: PWY-7900	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_044265997.1	10	Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-983231	"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production"
XP_044262762.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044253410.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044266917.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_044258475.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044257952.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_044253402.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044259943.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_044260060.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_044267586.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044257715.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_044255539.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044254271.1	16	Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5693616	"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_044265587.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_044272420.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_044253421.1	5	KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-5269;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Synthesis of PG";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044258581.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736	"MHC class II antigen presentation";"Gap junction assembly";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Kinesins";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
XP_044270081.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_044264031.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_044260460.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159227	"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA"
XP_044255154.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;Reactome: R-HSA-983231;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855204;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6365;MetaCyc: PWY-6366;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_044262349.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044258055.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571	"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation"
XP_044259695.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_044263699.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_044265284.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_044259630.1	12	Reactome: R-HSA-2691232;Reactome: R-HSA-75893;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044265403.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044268580.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_044269146.1	8	Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1	"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II"
XP_044263573.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_044267090.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_044257997.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044258076.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_044272134.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_044266182.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_044263374.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044270391.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044270302.1	12	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Thermogenesis";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044263357.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044258158.1	17	Reactome: R-HSA-9022692;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-4615885;Reactome: R-HSA-174178;KEGG: 05163+2.7.11.1;Reactome: R-HSA-141444	"Regulation of MECP2 expression and activity";"Human papillomavirus infection";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Thermogenesis";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA replication proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human cytomegalovirus infection";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044261469.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044252470.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_044268868.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044269836.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_044258769.1	10	Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_044272777.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111463	"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs"
XP_044257278.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_044262606.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044272768.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044261942.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-3371571	"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"HSF1-dependent transactivation"
XP_044255935.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044270421.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation"
XP_044261456.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_044253224.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044260873.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_044260695.1	12	MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism"
XP_044263215.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044268509.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949	"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin"
XP_044268605.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044271625.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044253168.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044263008.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044266731.1	13	MetaCyc: PWY-7821;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.66	"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine catabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism"
XP_044266403.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044263208.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_044252984.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_044257671.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_044272194.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044256349.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_044265126.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044269365.1	17	Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606	"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_044258304.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_044258337.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220	"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Kinesins";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Gap junction assembly";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins"
XP_044267285.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044267189.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044265295.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_044260723.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044255939.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044254205.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044269555.1	5	KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_044252430.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044267851.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044267666.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044257936.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044272735.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044269162.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044268055.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044272706.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044269346.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_044256283.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044255386.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_044258195.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_044258385.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_044258212.1	6	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_044265163.1	13	MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030	"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate polyglutamylation";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"L-histidine degradation III"
XP_044256900.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044270055.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_044269689.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044271887.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044264755.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52	"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation"
XP_044257226.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_044270899.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044263630.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044271711.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_044271728.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_044264566.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_044271100.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-5687128	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"MAPK6/MAPK4 signaling"
XP_044259495.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_044264712.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_044260603.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044268606.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_044256437.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044262453.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_044260537.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_044259421.1	8	MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Propanoate metabolism"
XP_044263670.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"HDACs deacetylate histones";"HCMV Early Events"
XP_044264562.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044256748.1	52	Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-5601884;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping"
XP_044272179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044254299.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_044256905.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044268575.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_044266970.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_044253283.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044252575.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044264083.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_044256416.1	5	KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074	"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Butanoate metabolism";"Mevalonate degradation"
XP_044252335.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044255468.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044265256.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044269756.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044270770.1	6	KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I"
XP_044263995.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6"
XP_044268403.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667;Reactome: R-HSA-1483166	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA"
XP_044254942.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044269418.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_044253699.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044256665.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044264718.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044256049.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_044253947.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_044256927.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_044271744.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044265625.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044267430.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044253974.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044255807.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044254483.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_044262039.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_044262245.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044268919.1	14	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2022377;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_044263372.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702	"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Hedgehog 'on' state";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling"
XP_044260751.1	40	KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6945;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-6944;MetaCyc: PWY-5138;MetaCyc: PWY-7094;MetaCyc: PWY-7779;MetaCyc: PWY-7654;MetaCyc: PWY-6435;MetaCyc: PWY-7606;MetaCyc: PWY-5109;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-5136;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-5789	"Benzoate degradation";"Tryptophan metabolism";"Geraniol degradation";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Aminobenzoate degradation";"Caprolactam degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Benzoyl-coa degradation I (aerobic)";"Androstenedione degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid salvage";"Methyl tert-butyl ether degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fermentation to 2-methylbutanoate";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation II (plant peroxisome)";"Toluene degradation";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Limonene and pinene degradation";"Glutaryl-coa degradation";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"2-methylpropene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_044268612.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044253832.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044263671.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690	"HDACs deacetylate histones";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events"
XP_044262033.1	22	MetaCyc: PWY-7728;MetaCyc: PWY-7035;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7592;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6958	"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_044259374.1	8	KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27	"Pyruvate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis"
XP_044269493.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_044255447.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_044252631.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_044265722.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_044271381.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044261271.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_044265739.1	5	MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_044271771.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions";"ECM proteoglycans"
XP_044256278.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_044256118.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044264315.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_044266423.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_044259726.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_044264018.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_044264868.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044271190.1	20	Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7288	"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_044264470.1	5	Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964	"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_044271989.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044267870.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_044271910.1	8	KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2	"Photosynthesis";"ATP biosynthesis";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Oxidative phosphorylation"
XP_044253722.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044261013.1	9	MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-7852;MetaCyc: PWY-6703	"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis"
XP_044252517.1	5	MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_044253576.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168333	"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_044268700.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_044263127.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_044255174.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044258780.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_044260558.1	31	MetaCyc: PWY-8049;MetaCyc: PWY-8047;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-7388;MetaCyc: PWY-6799;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7858;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-7663;MetaCyc: PWY-8012;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5989;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1	"Pederin biosynthesis";"Bryostatin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"Mupirocin biosynthesis";"";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_044261771.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090	"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures"
XP_044267664.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044255780.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044256026.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_044269826.1	2	Reactome: R-HSA-210746;Reactome: R-HSA-210745	"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells"
XP_044261642.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_044256807.1	16	MetaCyc: PWY-5538;KEGG: 00020+6.2.1.4;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384	"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Itaconate degradation";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_044267857.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_044266633.1	9	Reactome: R-HSA-68949;Reactome: R-HSA-1362277;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_044272173.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044265257.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_044259962.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_044264794.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044263914.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044267227.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044265279.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_044266807.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4086400	"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"PCP/CE pathway"
XP_044258428.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_044264198.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_044259542.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_044258545.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_044260696.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053	"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II"
XP_044256637.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044269386.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044261142.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044264953.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044253705.1	7	Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-7586	"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_044262190.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921	"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation"
XP_044265313.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-7328	"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_044260165.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_044259790.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044272355.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044269070.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_044262163.1	6	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism"
XP_044268539.1	5	KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_044270424.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8854050	"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_044259811.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_044260578.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044260776.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_044258542.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_044256096.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044268856.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044264987.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_044258890.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044271307.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_044260511.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044252790.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_044272373.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40	"Glycolysis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
XP_044266819.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044260933.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044252741.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_044268112.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_044263639.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8854050	"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_044259123.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_044265171.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_044264035.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_044257968.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_044265434.1	7	MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-2201	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Folate transformations I"
XP_044258851.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603	"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases"
XP_044255315.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044266288.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_044258876.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044264985.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_044252840.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044258757.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761	"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Neddylation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_044259003.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044267580.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy"
XP_044268793.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-561;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_044259976.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044265652.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044267241.1	25	Reactome: R-HSA-8949275;Reactome: R-HSA-8878166;Reactome: R-HSA-8931987;Reactome: R-HSA-8941284;Reactome: R-HSA-8941332;Reactome: R-HSA-9616222;Reactome: R-HSA-8939243;Reactome: R-HSA-9018519;Reactome: R-HSA-8951911;Reactome: R-HSA-8934593;Reactome: R-HSA-8941333;Reactome: R-HSA-8941858;Reactome: R-HSA-8877330;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-8939902;Reactome: R-HSA-8940973;Reactome: R-HSA-8939256;Reactome: R-HSA-8936459;Reactome: R-HSA-8941326;Reactome: R-HSA-8939242;Reactome: R-HSA-8939236;Reactome: R-HSA-8939247;Reactome: R-HSA-8939246;Reactome: R-HSA-8951936	"RUNX3 Regulates Immune Response and Cell Migration";"Transcriptional regulation by RUNX2";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in cell migration";"Transcriptional regulation of granulopoiesis";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Estrogen-dependent gene expression";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX2 expression and activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF"
XP_044268447.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044267400.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_044263303.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044263360.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044268023.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044269388.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044261848.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044260143.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_044267268.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-8852276	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_044269755.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044265312.1	10	MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;Reactome: R-HSA-70370	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism"
XP_044268842.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_044264496.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044256318.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes"
XP_044270568.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_044257598.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_044263144.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_044268039.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044261314.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_044258318.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_044270471.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044265059.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_044257311.1	57	Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-195253	"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Neutrophil degranulation";"Neddylation";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex"
XP_044267841.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044266424.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044269097.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_044260102.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_044271812.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044257342.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044265309.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044271434.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044255604.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044269730.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_044261335.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044253045.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_044267651.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044257610.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_044261984.1	6	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
XP_044255902.1	9	KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780	"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Biotin transport and metabolism"
XP_044268838.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins"
XP_044254613.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044264468.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964	"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_044261225.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044262161.1	6	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism"
XP_044263861.1	5	MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_044272165.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-112382	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex"
XP_044256344.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-180746	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"HCMV Late Events";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein"
XP_044262425.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_044254692.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044258977.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_044264831.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_044265536.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044267243.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I"
XP_044271724.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_044264339.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044263705.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044258373.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044267869.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_044260442.1	19	MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;Reactome: R-HSA-75105;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-5172;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5	"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)"
XP_044256235.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044266251.1	7	MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_044263924.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044265982.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_044266133.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044266153.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044258328.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism"
XP_044258696.1	11	Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;Reactome: R-HSA-1632852;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137	"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"Macroautophagy";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system"
XP_044264149.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_044257848.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Starch and sucrose metabolism";"Streptomycin biosynthesis"
XP_044253770.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_044264225.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044257153.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044259712.1	4	Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_044255590.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044268610.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044257684.1	7	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_044257286.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509	"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling"
XP_044261105.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044261203.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_044258609.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_044253913.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044256701.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_044259767.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044265015.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044261117.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_044255527.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044260397.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_044257839.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044263791.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044264354.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044257334.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044263876.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044265523.1	56	Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68827	"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex"
XP_044268405.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5667	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I"
XP_044271862.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044266942.1	12	Reactome: R-HSA-196780;Reactome: R-HSA-71032;KEGG: 00630+6.4.1.3;KEGG: 00720+6.4.1.3;KEGG: 00280+6.4.1.3;MetaCyc: PWYG-321;MetaCyc: PWY-7384;MetaCyc: PWY-6728;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.3;MetaCyc: PWY-5743	"Biotin transport and metabolism";"Propionyl-CoA catabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"3-hydroxypropanoate cycle"
XP_044258179.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000	"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF activation"
XP_044258161.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892	"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation"
XP_044260168.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_044257675.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_044252737.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_044256028.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_044255327.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044254600.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8854214	"RAB geranylgeranylation";"TBC/RABGAPs"
XP_044262591.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_044256653.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044269130.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044271647.1	28	Reactome: R-HSA-3371511;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-68962	"HSF1 activation";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex"
XP_044252560.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_044266146.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044261845.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_044269201.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_044260932.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_044264602.1	14	MetaCyc: PWY-7601;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_044270113.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_044271303.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_044259884.1	6	KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
XP_044268733.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044262588.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044268392.1	10	Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-163680	"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity"
XP_044258432.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044261857.1	6	KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-5723;MetaCyc: PWY-1861	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_044255176.1	5	MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_044272516.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044255246.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044257994.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_044257041.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_044253187.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044267905.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044263668.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-166058	"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_044258857.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044256489.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044253575.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044256682.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_044256722.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044253263.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044269896.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_044260601.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044260178.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187	"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress"
XP_044267520.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044254135.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events"
XP_044253754.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167161	"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation"
XP_044255816.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044266950.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_044263124.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044254682.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_044261591.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_044262071.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044264516.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_044271740.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_044252816.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_044258621.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044258192.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044268611.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044257295.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_044266325.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_044255568.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044268654.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation"
XP_044252982.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_044272095.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757	"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation"
XP_044265642.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_044255908.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_044269415.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-140875	"Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation"
XP_044265704.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044265296.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_044254062.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_044261438.1	7	Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Mitochondrial protein import";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044262520.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044259509.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-983231	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production"
XP_044272004.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_044252678.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_044257787.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044262852.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044264672.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_044272096.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_044264975.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044255532.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044266430.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044264384.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044262564.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044269380.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044267185.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044271447.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044265329.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044269349.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_044258180.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_044269481.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044269864.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972	"Thermogenesis";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_044253876.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_044271909.1	10	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_044266128.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044260478.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142	"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins"
XP_044261578.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_044259851.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_044264026.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_044269131.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044260320.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_044262146.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044269021.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_044256635.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_044265655.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
XP_044270475.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_044269843.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044264371.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044260506.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044271611.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_044262651.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044264990.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_044268734.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_044265741.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_044262307.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044253874.1	7	Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483166	"Synthesis of PG";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA"
XP_044255534.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044258596.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044256027.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044261049.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044257785.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044255312.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044260254.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044272774.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044260568.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044257227.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_044254209.1	6	KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6731;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Glycogen degradation II";"Starch degradation III";"Sucrose biosynthesis II"
XP_044265689.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044258234.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_044253748.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044272410.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044265040.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-6859;MetaCyc: PWY-7141;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7736	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis"
XP_044269611.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Hedgehog 'off' state";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling"
XP_044269889.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)"
XP_044253298.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway"
XP_044261419.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044257574.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_044266116.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_044256981.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1"
XP_044261639.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044272333.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044260867.1	15	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_044253684.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_044256106.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044254752.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69205	"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription"
XP_044256544.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Neddylation";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_044271775.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044267897.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044259992.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_044254359.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044258828.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_044265120.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-174430	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation"
XP_044253468.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044267060.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044266014.1	33	Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-69202;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-8939236;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-6781827	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Cyclin E associated events during G1/S transition";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_044266087.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044254408.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_044266450.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044268452.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044256842.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044258254.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_044257665.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_044256146.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_044269416.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-140875	"Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation"
XP_044254887.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_044257564.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044257862.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044259681.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044259965.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-437239	"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Recycling pathway of L1"
XP_044263293.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044272262.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_044256755.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749	"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"HCMV Early Events";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs"
XP_044267414.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_044252554.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_044271253.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044254353.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_044253682.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_044257646.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_044257667.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_044259365.1	8	MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_044255236.1	5	MetaCyc: PWY-7177;MetaCyc: PWY-7176;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185	"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I"
XP_044258257.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174184	"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_044267329.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_044265176.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_044272455.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044266053.1	6	Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-114508	"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis"
XP_044262763.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044262314.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044266645.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_044267232.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_044267028.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_044265280.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044253219.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_044254044.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044267316.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20	"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044268564.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_044254045.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044260439.1	20	Reactome: R-HSA-163765;KEGG: 00640+6.2.1.5;Reactome: R-HSA-1268020;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5172;Reactome: R-HSA-75105;MetaCyc: PWY-5537	"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle";"Acetyl-coa biosynthesis III (from citrate)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V"
XP_044266521.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_044265139.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_044258138.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_044260693.1	4	MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_044272782.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044270984.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044272334.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044258091.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837	"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Ion homeostasis";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases"
XP_044253677.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_044268603.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044252892.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044254491.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_044266292.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_044254605.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044257019.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_044261766.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_044266446.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-373753	"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Nephrin family interactions"